SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXM_A_IMNA2001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b2h PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Salmonella
enterica) 		PF00496
(SBP_bac_5) 		4 ALA A 445
PHE A 446
ALA A 469
LEU A 427
 None
 0.72A 2bxmA-1b2hA:
0.8		 2bxmA-1b2hA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i6q LACTOFERRIN

(Camelus
dromedarius) 		PF00405
(Transferrin) 		4 ALA A 529
PHE A 530
ALA A 534
LEU A 564
 None
 0.94A 2bxmA-1i6qA:
0.0		 2bxmA-1i6qA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j2r HYPOTHETICAL
ISOCHORISMATASE
FAMILY PROTEIN YECD

(Escherichia
coli) 		PF00857
(Isochorismatase) 		4 ALA A  53
ALA A  48
ARG A  47
LEU A  27
 None
 0.94A 2bxmA-1j2rA:
undetectable		 2bxmA-1j2rA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN

(Salmonella
enterica) 		PF00654
(Voltage_CLC) 		4 ALA A 370
PHE A 371
ALA A 375
LEU A 254
 None
 0.40A 2bxmA-1kplA:
1.0		 2bxmA-1kplA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lva SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR

(Moorella
thermoacetica) 		PF09105
(SelB-wing_1)
PF09106
(SelB-wing_2)
PF09107
(SelB-wing_3) 		4 SER A 589
PHE A 593
ALA A 598
LEU A 613
 None
 0.83A 2bxmA-1lvaA:
0.4		 2bxmA-1lvaA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE

(Enterobacter
cloacae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ALA A 197
PHE A 198
ALA A 202
LEU A 331
 None
 0.56A 2bxmA-1ovmA:
0.0		 2bxmA-1ovmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ps9 2,4-DIENOYL-COA
REDUCTASE

(Escherichia
coli) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 ALA A 387
PHE A 388
ALA A 392
LEU A 376
 None
 0.57A 2bxmA-1ps9A:
0.0		 2bxmA-1ps9A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qjm LACTOFERRIN

(Equus caballus) 		PF00405
(Transferrin) 		4 ALA A 529
PHE A 530
ALA A 534
LEU A 564
 None
 0.91A 2bxmA-1qjmA:
undetectable		 2bxmA-1qjmA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rif DNA HELICASE UVSW

(Escherichia
virus T4) 		PF04851
(ResIII) 		4 ALA A 174
ALA A 146
ARG A 150
LEU A 143
 None
 0.82A 2bxmA-1rifA:
undetectable		 2bxmA-1rifA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rwr FILAMENTOUS
HEMAGGLUTININ

(Bordetella
pertussis) 		PF05860
(Haemagg_act) 		4 SER A 174
ALA A 182
PHE A 160
LEU A 124
 None
 0.89A 2bxmA-1rwrA:
undetectable		 2bxmA-1rwrA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb8 WBPP

(Pseudomonas
aeruginosa) 		PF01370
(Epimerase) 		4 ALA A  50
PHE A  49
ALA A  25
LEU A  57
 NAD  A 342 (-4.1A)
None
NAD  A 342 (-4.2A)
None
 0.89A 2bxmA-1sb8A:
undetectable		 2bxmA-1sb8A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szq 2-METHYLCITRATE
DEHYDRATASE

(Escherichia
coli) 		PF03972
(MmgE_PrpD) 		4 ALA A  89
PHE A  90
ALA A  94
ARG A  97
 None
 0.85A 2bxmA-1szqA:
undetectable		 2bxmA-1szqA:
21.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		4 ALA A 210
PHE A 211
ALA A 215
LEU A 238
 DKA  A1002 (-3.3A)
None
None
DKA  A1003 (-4.3A)
 0.24A 2bxmA-1tf0A:
38.4		 2bxmA-1tf0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkc TRANSKETOLASE

(Saccharomyces
cerevisiae) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ALA A 430
PHE A 431
ALA A 433
LEU A 135
 None
 0.75A 2bxmA-1tkcA:
3.8		 2bxmA-1tkcA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vax URIC ACID OXIDASE

(Arthrobacter
globiformis) 		PF01014
(Uricase) 		4 PHE A  82
ALA A  78
ARG A  79
LEU A  27
 None
 0.92A 2bxmA-1vaxA:
undetectable		 2bxmA-1vaxA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wsu SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR

(Moorella
thermoacetica) 		PF09107
(SelB-wing_3) 		4 SER A 589
PHE A 593
ALA A 598
LEU A 613
 None
 0.88A 2bxmA-1wsuA:
undetectable		 2bxmA-1wsuA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xcf TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Escherichia
coli) 		PF00290
(Trp_syntA) 		4 SER A   6
PHE A   8
ALA A  18
LEU A 209
 None
 0.92A 2bxmA-1xcfA:
undetectable		 2bxmA-1xcfA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8q UBIQUITIN-LIKE 2
ACTIVATING ENZYME
E1B

(Homo sapiens) 		PF00899
(ThiF)
PF14732
(UAE_UbL)
PF16195
(UBA2_C) 		4 ALA B 319
PHE B 322
ALA B 358
ARG B 362
 None
 0.85A 2bxmA-1y8qB:
undetectable		 2bxmA-1y8qB:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0g WINDBEUTEL PROTEIN

(Drosophila
melanogaster) 		PF07749
(ERp29)
PF07912
(ERp29_N) 		4 ALA A1064
PHE A1065
ALA A1069
LEU A1076
 None
 0.86A 2bxmA-2c0gA:
2.6		 2bxmA-2c0gA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cb4 MOSQUITOCIDAL TOXIN

(Lysinibacillus
sphaericus) 		no annotation 4 ALA A  44
PHE A 200
ALA A 175
LEU A  95
 None
 0.78A 2bxmA-2cb4A:
undetectable		 2bxmA-2cb4A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cx1 HYPOTHETICAL PROTEIN
APE0525

(Aeropyrum
pernix) 		PF01472
(PUA)
PF09183
(DUF1947) 		4 SER A 148
ALA A 144
ALA A 129
LEU A 131
 None
 0.93A 2bxmA-2cx1A:
undetectable		 2bxmA-2cx1A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dht 409AA LONG
HYPOTHETICAL
NADP-DEPENDENT
ISOCITRATE
DEHYDROGENASE

(Sulfurisphaera
tokodaii) 		PF00180
(Iso_dh) 		4 ALA A 233
PHE A 234
ALA A 238
LEU A 291
 None
 0.30A 2bxmA-2dhtA:
undetectable		 2bxmA-2dhtA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwu GLUTAMATE RACEMASE

(Bacillus
anthracis) 		PF01177
(Asp_Glu_race) 		5 SER A 244
PHE A 248
ALA A 252
ARG A 254
LEU A  20
 None
 1.41A 2bxmA-2dwuA:
undetectable		 2bxmA-2dwuA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3v NEURAL CELL ADHESION
MOLECULE 1, 140 KDA
ISOFORM

(Homo sapiens) 		PF00041
(fn3) 		4 SER A 101
PHE A 103
ALA A  25
LEU A  76
 None
 0.83A 2bxmA-2e3vA:
undetectable		 2bxmA-2e3vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7m HYALURONIDASE

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		4 SER A 635
ALA A 645
ALA A 760
ARG A 690
 None
None
None
GAL  A1770 ( 2.8A)
 0.90A 2bxmA-2j7mA:
undetectable		 2bxmA-2j7mA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ja2 GLUTAMYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00749
(tRNA-synt_1c) 		4 ALA A 361
PHE A 362
ALA A 366
LEU A 344
 None
 0.61A 2bxmA-2ja2A:
undetectable		 2bxmA-2ja2A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mgy TRANSLOCATOR PROTEIN

(Mus musculus) 		PF03073
(TspO_MBR) 		4 ALA A 119
ALA A 125
ARG A 128
LEU A  84
 None
 0.79A 2bxmA-2mgyA:
2.9		 2bxmA-2mgyA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oca ATP-DEPENDENT DNA
HELICASE UVSW

(Escherichia
virus T4) 		PF00271
(Helicase_C)
PF04851
(ResIII) 		4 ALA A 174
ALA A 146
ARG A 150
LEU A 143
 None
 0.82A 2bxmA-2ocaA:
undetectable		 2bxmA-2ocaA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbk KSHV PROTEASE

(Human
gammaherpesvirus
8) 		PF00716
(Peptidase_S21) 		4 ALA A  75
PHE A  76
ALA A  80
LEU A 106
 None
 0.94A 2bxmA-2pbkA:
undetectable		 2bxmA-2pbkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pzk PUTATIVE NUCLEOTIDE
SUGAR EPIMERASE/
DEHYDRATASE

(Bordetella
bronchiseptica) 		PF01370
(Epimerase) 		4 ALA A  34
PHE A  33
ALA A   9
LEU A  41
 NAD  A 401 (-3.9A)
None
NAD  A 401 (-4.1A)
None
 0.94A 2bxmA-2pzkA:
undetectable		 2bxmA-2pzkA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqk NEUROPILIN-2

(Homo sapiens) 		PF00431
(CUB)
PF00754
(F5_F8_type_C) 		4 SER A 461
ALA A 465
ALA A 506
ARG A 507
 None
 0.94A 2bxmA-2qqkA:
undetectable		 2bxmA-2qqkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr6 IMP
DEHYDROGENASE/GMP
REDUCTASE

(Corynebacterium
glutamicum) 		PF00478
(IMPDH) 		4 SER A  56
ALA A 297
PHE A  64
ALA A 293
 None
 0.80A 2bxmA-2qr6A:
undetectable		 2bxmA-2qr6A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9h H(+)/CL(-) EXCHANGE
TRANSPORTER CLCA

(Escherichia
coli) 		PF00654
(Voltage_CLC) 		4 ALA A 370
PHE A 371
ALA A 375
LEU A 254
 None
 0.42A 2bxmA-2r9hA:
1.3		 2bxmA-2r9hA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfa TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 6

(Mus musculus) 		PF12796
(Ank_2)
PF13637
(Ank_4) 		4 SER A  62
ALA A  52
ALA A  86
LEU A  83
 None
 0.84A 2bxmA-2rfaA:
undetectable		 2bxmA-2rfaA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vsa MOSQUITOCIDAL TOXIN

(Lysinibacillus
sphaericus) 		PF05588
(Botulinum_HA-17)
PF14200
(RicinB_lectin_2) 		4 ALA A  44
PHE A 200
ALA A 175
LEU A  95
 None
 0.84A 2bxmA-2vsaA:
undetectable		 2bxmA-2vsaA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1b DELTA-AMINOLEVULINIC
ACID DEHYDRATASE

(Mus musculus) 		PF00490
(ALAD) 		4 PHE A  36
ALA A 211
ARG A 209
LEU A  50
 None
 0.93A 2bxmA-2z1bA:
undetectable		 2bxmA-2z1bA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z37 CHITINASE

(Brassica juncea) 		PF00182
(Glyco_hydro_19) 		4 ALA A 178
PHE A 179
ALA A 183
LEU A 147
 None
 0.94A 2bxmA-2z37A:
undetectable		 2bxmA-2z37A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak8 DNA PROTECTION
DURING STARVATION
PROTEIN

(Salmonella
enterica) 		PF00210
(Ferritin) 		4 SER A 152
PHE A 148
ALA A 139
LEU A  32
 None
 0.86A 2bxmA-3ak8A:
3.5		 2bxmA-3ak8A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE EPSILON SUBUNIT

(Methanosarcina
barkeri) 		PF02552
(CO_dh) 		4 ALA G  21
PHE G 151
ALA G  27
LEU G 166
 None
 0.91A 2bxmA-3cf4G:
undetectable		 2bxmA-3cf4G:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctt MALTASE-GLUCOAMYLASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 SER A 597
TRP A 674
ALA A 652
LEU A 558
 None
 0.85A 2bxmA-3cttA:
undetectable		 2bxmA-3cttA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hb7 ISOCHORISMATASE
HYDROLASE

(Alkaliphilus
metalliredigens) 		PF00857
(Isochorismatase) 		4 SER A 132
ALA A 103
PHE A 102
LEU A 111
 NA  A 202 (-3.6A)
None
None
None
 0.92A 2bxmA-3hb7A:
undetectable		 2bxmA-3hb7A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ikm DNA POLYMERASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00476
(DNA_pol_A) 		4 ALA A 143
TRP A1118
ALA A1115
LEU A1159
 None
 0.79A 2bxmA-3ikmA:
2.2		 2bxmA-3ikmA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Thermus
thermophilus) 		PF01425
(Amidase) 		4 ALA E 146
ALA E 154
ARG E  27
LEU E 106
 None
 0.82A 2bxmA-3kfuE:
undetectable		 2bxmA-3kfuE:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lws AROMATIC AMINO ACID
BETA-ELIMINATING
LYASE/THREONINE
ALDOLASE

(Exiguobacterium
sibiricum) 		PF01212
(Beta_elim_lyase) 		4 ALA A 220
PHE A 221
ALA A 225
LEU A 215
 None
 0.77A 2bxmA-3lwsA:
undetectable		 2bxmA-3lwsA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mb2 4-OXALOCROTONATE
TAUTOMERASE FAMILY
ENZYME - BETA
SUBUNIT

(Chloroflexus
aurantiacus) 		no annotation 4 ALA B  20
PHE B  21
ALA B  25
LEU B   3
 None
 0.68A 2bxmA-3mb2B:
undetectable		 2bxmA-3mb2B:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtr NEURAL CELL ADHESION
MOLECULE 1

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set) 		4 SER A 591
PHE A 593
ALA A 515
LEU A 566
 None
 0.88A 2bxmA-3mtrA:
undetectable		 2bxmA-3mtrA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ose SERINE/THREONINE-PRO
TEIN KINASE MARK1

(Homo sapiens) 		PF02149
(KA1) 		4 SER A 776
ALA A 781
PHE A 782
ALA A 786
 None
 0.69A 2bxmA-3oseA:
undetectable		 2bxmA-3oseA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ri6 O-ACETYLHOMOSERINE
SULFHYDRYLASE

(Wolinella
succinogenes) 		PF01053
(Cys_Met_Meta_PP) 		4 ALA A 243
PHE A 244
ALA A 248
LEU A 218
 None
 0.91A 2bxmA-3ri6A:
undetectable		 2bxmA-3ri6A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tch PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ALA A 471
PHE A 472
ALA A 495
LEU A 453
 None
 0.75A 2bxmA-3tchA:
2.1		 2bxmA-3tchA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tz6 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ALA A 265
PHE A 264
ARG A 272
LEU A 317
 None
 0.80A 2bxmA-3tz6A:
undetectable		 2bxmA-3tz6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wgc L-ALLO-THREONINE
ALDOLASE

(Aeromonas
jandaei) 		PF01212
(Beta_elim_lyase) 		4 ALA A 214
PHE A 215
ALA A 219
LEU A 209
 None
 0.85A 2bxmA-3wgcA:
undetectable		 2bxmA-3wgcA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a45 ALPHA-N-ACETYLGLUCOS
AMINIDASE FAMILY
PROTEIN

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		4 SER A1368
ALA A1379
ALA A1486
ARG A1423
 None
None
None
NGA  A2494 (-2.6A)
 0.72A 2bxmA-4a45A:
undetectable		 2bxmA-4a45A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ax2 RAP1B

(Serratia
marcescens) 		PF16695
(Tai4) 		4 ALA A  64
PHE A  65
ALA A  69
LEU A  55
 None
 0.68A 2bxmA-4ax2A:
3.1		 2bxmA-4ax2A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3i FATTY ACID
BETA-OXIDATION
COMPLEX ALPHA-CHAIN
FADB

(Mycobacterium
tuberculosis) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ALA A 696
PHE A 697
ALA A 701
LEU A 645
 None
 0.82A 2bxmA-4b3iA:
2.5		 2bxmA-4b3iA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dhi UBIQUITIN
THIOESTERASE
OTUBAIN-LIKE

(Caenorhabditis
elegans) 		PF10275
(Peptidase_C65) 		4 ALA B  64
PHE B  65
ALA B  69
LEU B  53
 None
 0.69A 2bxmA-4dhiB:
2.9		 2bxmA-4dhiB:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e72 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF11738
(DUF3298) 		4 ALA A 166
PHE A 167
ALA A 171
LEU A 211
 None
 0.94A 2bxmA-4e72A:
undetectable		 2bxmA-4e72A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g8k 2-5A-DEPENDENT
RIBONUCLEASE

(Homo sapiens) 		PF12796
(Ank_2)
PF13857
(Ank_5) 		4 ALA A 128
PHE A 129
ALA A 133
LEU A 187
 None
 0.93A 2bxmA-4g8kA:
undetectable		 2bxmA-4g8kA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9x PROTEIN UL141

(Human
betaherpesvirus
5) 		PF16758
(UL141) 		5 ALA A 138
PHE A  83
ALA A  81
ARG A  80
LEU A 107
 None
 1.32A 2bxmA-4i9xA:
undetectable		 2bxmA-4i9xA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j6e UDP-2,3-DIACYLGLUCOS
AMINE
PYROPHOSPHATASE LPXI

(Caulobacter
vibrioides) 		PF06230
(DUF1009) 		4 ALA A 264
ALA A 237
ARG A 236
LEU A 212
 None
 0.91A 2bxmA-4j6eA:
undetectable		 2bxmA-4j6eA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgv NUCLEAR RECEPTOR
SUBFAMILY 4 GROUP A
MEMBER 1

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 ALA A 488
PHE A 489
ALA A 452
LEU A 449
 None
 0.77A 2bxmA-4jgvA:
undetectable		 2bxmA-4jgvA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmw GLUTATHIONE
TRANSFERASE

(Phanerochaete
chrysosporium) 		PF13417
(GST_N_3) 		4 ALA A 116
PHE A 117
ALA A 121
LEU A 207
 None
 0.50A 2bxmA-4lmwA:
1.7		 2bxmA-4lmwA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0f IGG RECEPTOR FCRN
LARGE SUBUNIT P51

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 ALA A  23
PHE A  24
TRP A  25
LEU A  68
 None
 0.92A 2bxmA-4n0fA:
2.4		 2bxmA-4n0fA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6b SERINE
ACETYLTRANSFERASE
APOENZYME

(Glycine max) 		PF00132
(Hexapep)
PF06426
(SATase_N) 		4 PHE A 151
ALA A 124
ARG A 126
LEU A  60
 None
 0.91A 2bxmA-4n6bA:
2.1		 2bxmA-4n6bA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nmw PIMELYL-[ACYL-CARRIE
R PROTEIN] METHYL
ESTER ESTERASE

(Salmonella
enterica) 		PF00561
(Abhydrolase_1) 		4 SER A 240
ALA A 244
PHE A 245
LEU A  79
 None
 0.88A 2bxmA-4nmwA:
undetectable		 2bxmA-4nmwA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q88 UNCHARACTERIZED
PROTEIN

(Bacteroides
vulgatus) 		PF07470
(Glyco_hydro_88) 		4 ALA A 360
PHE A 361
ALA A 365
ARG A 368
 None
 0.69A 2bxmA-4q88A:
undetectable		 2bxmA-4q88A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlv ANKYRIN-1, ANKYRIN-2

(Homo sapiens;
Mus musculus) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		4 SER A2646
ALA A2636
ALA A2669
LEU A2666
 None
 0.72A 2bxmA-4rlvA:
undetectable		 2bxmA-4rlvA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uph SULFATASE (SULFURIC
ESTER HYDROLASE)
PROTEIN

(Agrobacterium
tumefaciens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 SER A 348
ALA A  59
PHE A  58
ALA A 414
 None
 0.93A 2bxmA-4uphA:
undetectable		 2bxmA-4uphA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yip SUPEROXIDE DISMUTASE
[MN/FE]

(Streptococcus
mutans) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 ALA A 115
PHE A 116
ALA A 120
ARG A 123
 None
 0.30A 2bxmA-4yipA:
undetectable		 2bxmA-4yipA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d95 AMINOTRANSFERASE
CLASS-III

(Sphaerobacter
thermophilus) 		PF00202
(Aminotran_3) 		4 ALA A 397
PHE A 398
ALA A 444
LEU A 441
 None
 0.92A 2bxmA-5d95A:
undetectable		 2bxmA-5d95A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejj UFM1-SPECIFIC
PROTEASE

(Caenorhabditis
elegans) 		PF07910
(Peptidase_C78) 		4 ALA A 274
PHE A 275
ALA A 279
LEU A 166
 None
 0.65A 2bxmA-5ejjA:
undetectable		 2bxmA-5ejjA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ema SORTING NEXIN-27

(Rattus
norvegicus) 		PF00595
(PDZ) 		4 SER A  82
PHE A  55
ARG A 122
LEU A 128
 None
 0.83A 2bxmA-5emaA:
undetectable		 2bxmA-5emaA:
10.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		4 ALA A 210
PHE A 211
ARG A 218
LEU A 238
 None
 0.89A 2bxmA-5ghkA:
39.1		 2bxmA-5ghkA:
79.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4v GLUTAMATE--TRNA
LIGASE

(Xanthomonas
oryzae) 		no annotation 4 SER A 405
ALA A 391
ARG A 392
LEU A 428
 None
 0.74A 2bxmA-5h4vA:
undetectable		 2bxmA-5h4vA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6j PIERISIN-1

(Pieris rapae) 		no annotation 4 ALA A  15
PHE A 168
ALA A 144
LEU A  68
 None
 0.81A 2bxmA-5h6jA:
undetectable		 2bxmA-5h6jA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6n PIERISIN-1

(Pieris rapae) 		no annotation 4 ALA A  15
PHE A 168
ALA A 144
LEU A  68
 None
 0.78A 2bxmA-5h6nA:
undetectable		 2bxmA-5h6nA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb4 NUP192,NUCLEOPORIN
NUP192

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 ALA B1337
PHE B1338
ALA B1342
LEU B1321
 None
 0.47A 2bxmA-5hb4B:
3.5		 2bxmA-5hb4B:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5id3 MITOCHONDRIAL
CALCIUM UNIPORTER

(Caenorhabditis
elegans) 		PF04678
(MCU) 		4 ALA A 220
PHE A 219
ALA A 215
ARG A 213
 None
 0.88A 2bxmA-5id3A:
undetectable		 2bxmA-5id3A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iys PHYTOENE SYNTHASE

(Enterococcus
hirae) 		PF00494
(SQS_PSY) 		4 ALA A  50
PHE A  51
ALA A  55
LEU A 110
 None
 0.85A 2bxmA-5iysA:
undetectable		 2bxmA-5iysA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jhq TANKYRASE-1

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13606
(Ank_3) 		4 SER A 266
ALA A 256
ALA A 289
LEU A 286
 None
 0.90A 2bxmA-5jhqA:
undetectable		 2bxmA-5jhqA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpq ES8

(Chaetomium
thermophilum) 		no annotation 4 LYS t  83
ALA t 186
ARG t 185
LEU t  68
 U  2 259 ( 2.0A)
None
U  2 208 ( 1.6A)
None
 0.92A 2bxmA-5jpqt:
2.9		 2bxmA-5jpqt:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5klp ORF34

(Pseudomonas
syringae) 		PF03421
(Acetyltransf_14) 		4 ALA A 203
ALA A 154
ARG A 134
LEU A 121
 None
 0.82A 2bxmA-5klpA:
undetectable		 2bxmA-5klpA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lqd ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE

(Streptomyces
venezuelae) 		PF00982
(Glyco_transf_20) 		4 ALA A 206
PHE A 207
ALA A 211
LEU A 191
 None
 0.89A 2bxmA-5lqdA:
undetectable		 2bxmA-5lqdA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93

(Porphyromonas
gingivalis) 		no annotation 4 LYS A  70
ALA A  52
PHE A  51
LEU A 107
 None
 0.94A 2bxmA-5m11A:
undetectable		 2bxmA-5m11A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrw POTASSIUM-TRANSPORTI
NG ATPASE
POTASSIUM-BINDING
SUBUNIT

(Escherichia
coli) 		PF03814
(KdpA) 		4 SER A 119
ALA A 238
PHE A 236
LEU A 195
 None
 0.93A 2bxmA-5mrwA:
undetectable		 2bxmA-5mrwA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6c D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Homo sapiens) 		no annotation 4 ALA A 223
PHE A 222
ALA A 248
LEU A 245
 None
 0.94A 2bxmA-5n6cA:
undetectable		 2bxmA-5n6cA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0s GLUCOSYLCERAMIDASE

(Thermoanaerobacterium
xylanolyticum) 		PF04685
(DUF608)
PF12215
(Glyco_hydr_116N)
PF17168
(DUF5127) 		4 SER A 112
ALA A 319
PHE A 213
LEU A 338
 None
 0.83A 2bxmA-5o0sA:
2.4		 2bxmA-5o0sA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ovo ADP-RIBOSYL-(DINITRO
GEN REDUCTASE)
HYDROLASE

(Azospirillum
brasilense) 		no annotation 4 ALA A  88
PHE A  87
ALA A  83
LEU A  68
 None
 0.92A 2bxmA-5ovoA:
undetectable		 2bxmA-5ovoA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tc1 MATURATION PROTEIN

(Escherichia
virus MS2) 		PF03863
(Phage_mat-A) 		4 SER M 151
ALA M 383
ALA M 159
LEU M 206
 None
 0.87A 2bxmA-5tc1M:
1.5		 2bxmA-5tc1M:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um6 UBIQUITIN-ACTIVATING
ENZYME E1 1

(Schizosaccharomyces
pombe) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		4 SER A 730
PHE A 822
ALA A 826
LEU A 612
 None
 0.92A 2bxmA-5um6A:
undetectable		 2bxmA-5um6A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf3 CAPSID VERTEX
PROTEIN GP24

(Escherichia
virus T4) 		PF07068
(Gp23) 		4 ALA a 117
PHE a 116
ALA a 131
LEU a 128
 None
 0.80A 2bxmA-5vf3a:
undetectable		 2bxmA-5vf3a:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vip MDCD

(Pseudomonas
aeruginosa) 		PF01039
(Carboxyl_trans) 		4 ALA B 151
ALA B 112
ARG B 111
LEU B 143
 None
 0.92A 2bxmA-5vipB:
undetectable		 2bxmA-5vipB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7i PALMITOYLTRANSFERASE
ZDHHC17

(Homo sapiens) 		PF12796
(Ank_2) 		4 SER A 242
ALA A 232
ALA A 265
LEU A 262
 None
 0.85A 2bxmA-5w7iA:
undetectable		 2bxmA-5w7iA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wpa SPLICING FACTOR,
PROLINE- AND
GLUTAMINE-RICH

(Homo sapiens) 		no annotation 4 ALA A 318
PHE A 317
ALA A 348
LEU A 299
 None
 0.87A 2bxmA-5wpaA:
undetectable		 2bxmA-5wpaA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wrp PYRUVATE KINASE

(Mycobacterium
tuberculosis) 		no annotation 4 SER A 376
ALA A 384
ARG A 385
LEU A 392
 PO4  A 501 (-2.6A)
None
None
None
 0.92A 2bxmA-5wrpA:
undetectable		 2bxmA-5wrpA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wwo ESSENTIAL NUCLEAR
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF05291
(Bystin) 		4 ALA A 420
PHE A 421
ALA A 425
LEU A 460
 None
 0.90A 2bxmA-5wwoA:
2.6		 2bxmA-5wwoA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xww AMPHB

(Streptomyces
nodosus) 		no annotation 4 ALA A  78
PHE A  76
ARG A  51
LEU A  69
 None
 0.73A 2bxmA-5xwwA:
undetectable		 2bxmA-5xwwA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y4d ANKYRIN-1,ANKYRIN-2,
ANKYRIN-2

(Homo sapiens;
Mus musculus) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4) 		4 SER A2646
ALA A2636
ALA A2669
LEU A2666
 None
 0.69A 2bxmA-5y4dA:
undetectable		 2bxmA-5y4dA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y4f ANKYRIN-2

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		4 SER A 645
ALA A 635
ALA A 668
LEU A 665
 None
 0.74A 2bxmA-5y4fA:
undetectable		 2bxmA-5y4fA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9d SERINE/THREONINE-PRO
TEIN KINASE
MARK1,SERINE/THREONI
NE-PROTEIN KINASE
MARK1

(Homo sapiens) 		no annotation 4 SER A 776
ALA A 781
PHE A 782
ALA A 786
 None
 0.89A 2bxmA-6c9dA:
undetectable		 2bxmA-6c9dA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fai ESSENTIAL NUCLEAR
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 ALA i 420
PHE i 421
ALA i 425
LEU i 460
 None
 0.94A 2bxmA-6faii:
2.6		 2bxmA-6faii:
9.30