SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXK_A_IMNA2001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1au7 PROTEIN PIT-1

(Rattus
norvegicus) 		PF00046
(Homeobox)
PF00157
(Pou) 		4 SER A  68
PHE A  50
ALA A  60
LEU A  53
 None
 1.17A 2bxkA-1au7A:
undetectable		 2bxkA-1au7A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebp EPO RECEPTOR

(Homo sapiens) 		PF00041
(fn3)
PF09067
(EpoR_lig-bind) 		4 PHE A 194
ALA A 129
ARG A 130
LEU A 218
 None
 0.92A 2bxkA-1ebpA:
undetectable		 2bxkA-1ebpA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fc4 2-AMINO-3-KETOBUTYRA
TE CONENZYME A
LIGASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 SER A 138
PHE A 119
LEU A 177
ASP A 211
 PLP  A1201 ( 4.0A)
None
None
None
 1.17A 2bxkA-1fc4A:
0.4		 2bxkA-1fc4A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gh6 RETINOBLASTOMA-ASSOC
IATED PROTEIN

(Homo sapiens) 		PF01857
(RB_B)
PF01858
(RB_A) 		4 LYS B 530
PHE B 526
LEU B 572
ASP B 479
 None
 1.12A 2bxkA-1gh6B:
1.0		 2bxkA-1gh6B:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl9 REVERSE GYRASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 SER B 528
PHE B 242
LEU B 220
ASP B 185
 None
 1.17A 2bxkA-1gl9B:
0.8		 2bxkA-1gl9B:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqj ALPHA-D-GLUCURONIDAS
E

(Cellvibrio
japonicus) 		PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M) 		4 TRP A 324
ALA A 326
LEU A 375
ASP A 303
 None
 1.02A 2bxkA-1gqjA:
2.3		 2bxkA-1gqjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3n 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
SYNTHASE II

(Thermus
thermophilus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PHE A 405
ALA A 348
LEU A 168
ASP A  85
 None
 1.10A 2bxkA-1j3nA:
undetectable		 2bxkA-1j3nA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfr HEMOGLOBIN

(Paramphistomum
epiclitum) 		PF00042
(Globin) 		4 SER A 110
PHE A 115
ALA A  31
LEU A  70
 None
HEM  A 148 (-4.8A)
None
HEM  A 148 (-4.6A)
 1.15A 2bxkA-1kfrA:
3.2		 2bxkA-1kfrA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lva SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR

(Moorella
thermoacetica) 		PF09105
(SelB-wing_1)
PF09106
(SelB-wing_2)
PF09107
(SelB-wing_3) 		4 SER A 589
PHE A 593
ALA A 598
LEU A 613
 None
 0.92A 2bxkA-1lvaA:
0.0		 2bxkA-1lvaA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no7 MAJOR CAPSID PROTEIN

(Human
alphaherpesvirus
1) 		PF03122
(Herpes_MCP) 		4 SER A 757
ALA A 498
LEU A 958
ASP A 562
 None
 1.16A 2bxkA-1no7A:
0.0		 2bxkA-1no7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pg7 MURINE ANTIBODY 6A6
FAB FRAGMENT

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER X  74
PHE X  29
ALA X  24
LEU X  34
 None
 1.05A 2bxkA-1pg7X:
undetectable		 2bxkA-1pg7X:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rur IMMUNOGLOBULIN 13G5,
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER H  74
PHE H  29
ALA H  24
LEU H  34
 None
 1.10A 2bxkA-1rurH:
undetectable		 2bxkA-1rurH:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw0 CONSERVED
HYPOTHETICAL PROTEIN

(Salmonella
enterica) 		PF02578
(Cu-oxidase_4) 		4 SER A  91
PHE A 112
ALA A 151
LEU A 202
 None
 1.10A 2bxkA-1rw0A:
undetectable		 2bxkA-1rw0A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smk MALATE
DEHYDROGENASE,
GLYOXYSOMAL

(Citrullus
lanatus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 PHE A 278
ALA A 281
LEU A 314
ASP A 213
 None
 1.12A 2bxkA-1smkA:
undetectable		 2bxkA-1smkA:
19.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		4 PHE A 211
ALA A 215
ARG A 218
LEU A 238
 None
None
CIT  A2001 (-4.0A)
DKA  A1003 (-4.3A)
 1.00A 2bxkA-1tf0A:
38.5		 2bxkA-1tf0A:
99.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txo PUTATIVE BACTERIAL
ENZYME

(Mycobacterium
tuberculosis) 		PF13672
(PP2C_2) 		4 ALA A 180
ARG A 181
LEU A   6
ASP A 126
 None
 1.05A 2bxkA-1txoA:
undetectable		 2bxkA-1txoA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uaz ARCHAERHODOPSIN-1

(Halorubrum
chaoviator) 		PF01036
(Bac_rhodopsin) 		4 SER A 113
ALA A 166
ARG A 169
LEU A 106
 None
 1.14A 2bxkA-1uazA:
2.6		 2bxkA-1uazA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vj0 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Thermotoga
maritima) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 SER A 205
PHE A 175
ALA A 174
LEU A 260
 None
 1.10A 2bxkA-1vj0A:
undetectable		 2bxkA-1vj0A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xat XENOBIOTIC
ACETYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00132
(Hexapep) 		4 PHE A  40
ALA A  44
ARG A  45
LEU A  57
 None
 1.17A 2bxkA-1xatA:
undetectable		 2bxkA-1xatA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xcf TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Escherichia
coli) 		PF00290
(Trp_syntA) 		4 SER A   6
PHE A   8
ALA A  18
LEU A 209
 None
 0.98A 2bxkA-1xcfA:
undetectable		 2bxkA-1xcfA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhe AEROBIC RESPIRATION
CONTROL PROTEIN ARCA

(Escherichia
coli) 		PF00072
(Response_reg) 		4 PHE A  23
ALA A 114
ARG A 113
LEU A  50
 None
 1.12A 2bxkA-1xheA:
undetectable		 2bxkA-1xheA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ag1 BENZALDEHYDE LYASE

(Pseudomonas
fluorescens) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 SER A 243
PHE A 412
ALA A 391
LEU A 400
 None
 1.16A 2bxkA-2ag1A:
undetectable		 2bxkA-2ag1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b92 INTERFERON-INDUCED
GUANYLATE-BINDING
PROTEIN 1

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		4 SER A 305
ALA A 117
LEU A 148
ASP A 108
 SER  A 305 ( 0.0A)
ALA  A 117 ( 0.0A)
LEU  A 148 ( 0.6A)
ASP  A 108 ( 0.6A)
 1.08A 2bxkA-2b92A:
undetectable		 2bxkA-2b92A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dha FLJ20171 PROTEIN

(Homo sapiens) 		PF00076
(RRM_1) 		4 PHE A 186
ALA A 226
ARG A 228
LEU A 241
 None
 1.15A 2bxkA-2dhaA:
undetectable		 2bxkA-2dhaA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dj1 PROTEIN
DISULFIDE-ISOMERASE
A4

(Mus musculus) 		PF00085
(Thioredoxin) 		4 SER A  85
PHE A  87
ALA A 103
LEU A  98
 None
 1.06A 2bxkA-2dj1A:
undetectable		 2bxkA-2dj1A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dou PROBABLE
N-SUCCINYLDIAMINOPIM
ELATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 SER A   8
PHE A  10
ALA A 340
ASP A 324
 None
 0.91A 2bxkA-2douA:
undetectable		 2bxkA-2douA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3v NEURAL CELL ADHESION
MOLECULE 1, 140 KDA
ISOFORM

(Homo sapiens) 		PF00041
(fn3) 		4 SER A 101
PHE A 103
ALA A  25
LEU A  76
 None
 0.84A 2bxkA-2e3vA:
undetectable		 2bxkA-2e3vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hes YDR267CP

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 PHE X 323
ALA X 313
LEU X  27
ASP X 318
 None
 1.06A 2bxkA-2hesX:
undetectable		 2bxkA-2hesX:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3g PDZ AND LIM DOMAIN
PROTEIN 7

(Homo sapiens) 		PF00595
(PDZ) 		4 SER A  31
PHE A  16
ARG A  71
LEU A  77
 None
 0.86A 2bxkA-2q3gA:
undetectable		 2bxkA-2q3gA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfv ISOCITRATE
DEHYDROGENASE [NADP]

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 SER A 239
PHE A 241
ALA A 202
LEU A 209
 None
 0.95A 2bxkA-2qfvA:
undetectable		 2bxkA-2qfvA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdt LEVANSUCRASE

(Bacillus
subtilis) 		PF02435
(Glyco_hydro_68) 		4 PHE A 107
ALA A 167
ARG A 176
LEU A  90
 None
 0.79A 2bxkA-2vdtA:
undetectable		 2bxkA-2vdtA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6d DYNAMIN FAMILY
PROTEIN

(Nostoc
punctiforme) 		PF00350
(Dynamin_N) 		4 SER A 626
PHE A 624
ALA A 470
ASP A 543
 None
 0.91A 2bxkA-2w6dA:
3.7		 2bxkA-2w6dA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ws9 P1

(Equine rhinitis
A virus) 		PF00073
(Rhv)
no annotation 		4 SER 3  17
PHE 1  38
ALA 1  67
LEU 1  71
 None
 1.03A 2bxkA-2ws93:
undetectable		 2bxkA-2ws93:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpi ANAPHASE-PROMOTING
COMPLEX SUBUNIT CUT9

(Schizosaccharomyces
pombe) 		PF12895
(ANAPC3)
PF13181
(TPR_8)
PF13424
(TPR_12) 		4 SER A 400
PHE A 396
ALA A 392
LEU A 384
 None
 1.07A 2bxkA-2xpiA:
undetectable		 2bxkA-2xpiA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ybu ACIDIC MAMMALIAN
CHITINASE

(Homo sapiens) 		PF00704
(Glyco_hydro_18) 		4 SER A 341
ALA A 357
LEU A 387
ASP A 365
 None
 1.15A 2bxkA-2ybuA:
undetectable		 2bxkA-2ybuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak8 DNA PROTECTION
DURING STARVATION
PROTEIN

(Salmonella
enterica) 		PF00210
(Ferritin) 		4 SER A 152
PHE A 148
ALA A 139
LEU A  32
 None
 0.92A 2bxkA-3ak8A:
2.3		 2bxkA-3ak8A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b3j HISTONE-ARGININE
METHYLTRANSFERASE
CARM1

(Rattus
norvegicus) 		PF06325
(PrmA) 		4 PHE A 344
ALA A 389
LEU A 349
ASP A 393
 None
 0.96A 2bxkA-3b3jA:
undetectable		 2bxkA-3b3jA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8i PA4872 OXALOACETATE
DECARBOXYLASE

(Pseudomonas
aeruginosa) 		PF13714
(PEP_mutase) 		4 PHE A  70
ALA A  74
ARG A  76
LEU A  47
 None
 1.15A 2bxkA-3b8iA:
undetectable		 2bxkA-3b8iA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clw CONSERVED EXPORTED
PROTEIN

(Bacteroides
fragilis) 		PF14587
(Glyco_hydr_30_2) 		4 SER A  46
TRP A 332
ALA A 374
LEU A 369
 None
 1.12A 2bxkA-3clwA:
undetectable		 2bxkA-3clwA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctt MALTASE-GLUCOAMYLASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 SER A 597
TRP A 674
ALA A 652
LEU A 558
 None
 0.87A 2bxkA-3cttA:
undetectable		 2bxkA-3cttA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3edy TRIPEPTIDYL-PEPTIDAS
E 1

(Homo sapiens) 		PF09286
(Pro-kuma_activ) 		4 SER A 125
PHE A 138
ALA A 136
LEU A 173
 None
 1.03A 2bxkA-3edyA:
undetectable		 2bxkA-3edyA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f41 PHYTASE

(Mitsuokella
multacida) 		PF14566
(PTPlike_phytase) 		4 PHE A 437
ALA A 471
LEU A 476
ASP A 463
 None
 1.10A 2bxkA-3f41A:
3.1		 2bxkA-3f41A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gde DNA LIGASE

(Archaeoglobus
fulgidus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 PHE A 310
ARG A 270
LEU A 314
ASP A 537
 None
PO4  A 556 ( 4.8A)
None
None
 1.15A 2bxkA-3gdeA:
2.1		 2bxkA-3gdeA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1t TYPE I SITE-SPECIFIC
RESTRICTION-MODIFICA
TION SYSTEM, R
(RESTRICTION)
SUBUNIT

(Vibrio
vulnificus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF13588
(HSDR_N_2) 		4 PHE A 533
ALA A 561
ARG A 378
LEU A 523
 None
 1.13A 2bxkA-3h1tA:
undetectable		 2bxkA-3h1tA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isp HTH-TYPE
TRANSCRIPTIONAL
REGULATOR
RV1985C/MT2039

(Mycobacterium
tuberculosis) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		4 PHE A 173
ALA A 190
ARG A 216
LEU A 178
 None
 1.16A 2bxkA-3ispA:
undetectable		 2bxkA-3ispA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mtr NEURAL CELL ADHESION
MOLECULE 1

(Homo sapiens) 		PF00041
(fn3)
PF07679
(I-set) 		4 SER A 591
PHE A 593
ALA A 515
LEU A 566
 None
 0.89A 2bxkA-3mtrA:
undetectable		 2bxkA-3mtrA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mx7 FAS APOPTOTIC
INHIBITORY MOLECULE
1

(Homo sapiens) 		PF06905
(FAIM1) 		4 PHE A  54
ALA A  63
LEU A  79
ASP A  14
 None
 0.92A 2bxkA-3mx7A:
undetectable		 2bxkA-3mx7A:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozy PUTATIVE MANDELATE
RACEMASE

(Bordetella
bronchiseptica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 SER A 145
ALA A 141
ARG A 140
LEU A 348
 None
 1.16A 2bxkA-3ozyA:
undetectable		 2bxkA-3ozyA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd8 PROBABLE
BACTERIOFERRITIN
BFRB

(Mycobacterium
tuberculosis) 		PF00210
(Ferritin) 		4 SER A  50
PHE A  48
ALA A  95
LEU A  92
 None
 1.07A 2bxkA-3qd8A:
2.7		 2bxkA-3qd8A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)

(Trypanosoma
brucei) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		4 SER A 353
PHE A 357
ALA A 375
LEU A 372
 FAD  A 501 (-3.4A)
FAD  A 501 (-3.7A)
None
None
 1.07A 2bxkA-3qd9A:
1.5		 2bxkA-3qd9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shw TIGHT JUNCTION
PROTEIN ZO-1

(Homo sapiens) 		PF00595
(PDZ)
PF00625
(Guanylate_kin)
PF07653
(SH3_2) 		4 PHE A 543
ALA A 559
ARG A 571
LEU A 535
 None
 1.15A 2bxkA-3shwA:
undetectable		 2bxkA-3shwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN

(Thermoproteus
tenax) 		no annotation 4 SER A 119
ALA A 104
ARG A 107
LEU A 110
 None
 1.10A 2bxkA-3tekA:
2.2		 2bxkA-3tekA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A

(Bacillus
subtilis) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		4 PHE A 919
ALA A 913
ARG A 914
LEU A 860
 None
 1.06A 2bxkA-3u44A:
undetectable		 2bxkA-3u44A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vup BETA-1,4-MANNANASE

(Aplysia kurodai) 		PF00150
(Cellulase) 		4 SER A 241
PHE A 256
ALA A 208
LEU A 159
 None
 1.16A 2bxkA-3vupA:
undetectable		 2bxkA-3vupA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wmt PROBABLE FERULOYL
ESTERASE B-1

(Aspergillus
oryzae) 		PF07519
(Tannase) 		4 PHE A 331
ALA A 323
ARG A 335
ASP A 286
 None
 0.84A 2bxkA-3wmtA:
undetectable		 2bxkA-3wmtA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0x TRANSCRIPTION FACTOR
FAPR

(Staphylococcus
aureus) 		PF03061
(4HBT) 		4 SER A 136
ALA A 154
ARG A 155
LEU A 125
 None
 1.08A 2bxkA-4a0xA:
undetectable		 2bxkA-4a0xA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b93 VESICLE-ASSOCIATED
MEMBRANE PROTEIN 7

(Mus musculus) 		PF00957
(Synaptobrevin)
PF13774
(Longin) 		4 PHE A  86
ALA A  94
ARG A  93
LEU A  15
 None
 1.03A 2bxkA-4b93A:
1.3		 2bxkA-4b93A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0p COP9 SIGNALOSOME
COMPLEX SUBUNIT 4

(Homo sapiens) 		PF01399
(PCI) 		4 SER A 172
ALA A 164
ARG A 198
LEU A 156
 None
 0.95A 2bxkA-4d0pA:
2.4		 2bxkA-4d0pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN

(Bacteroides
uniformis) 		PF12866
(DUF3823) 		4 SER A 216
ALA A 245
ARG A 246
LEU A 137
 None
None
PEG  A 305 (-3.2A)
None
 1.04A 2bxkA-4eiuA:
undetectable		 2bxkA-4eiuA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ell RETINOBLASTOMA-ASSOC
IATED PROTEIN

(Homo sapiens) 		PF01857
(RB_B)
PF01858
(RB_A) 		4 LYS A 530
PHE A 526
LEU A 572
ASP A 479
 None
 1.05A 2bxkA-4ellA:
undetectable		 2bxkA-4ellA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksf MALONYL-COA
DECARBOXYLASE

(Agrobacterium
vitis) 		PF05292
(MCD)
PF17408
(MCD_N) 		4 SER A  46
ALA A  57
LEU A 124
ASP A  36
 None
 1.11A 2bxkA-4ksfA:
undetectable		 2bxkA-4ksfA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lru GLYOXALASE III
(GLUTATHIONE-INDEPEN
DENT)

(Candida
albicans) 		PF01965
(DJ-1_PfpI) 		4 SER A  17
PHE A  15
LEU A 109
ASP A 169
 None
 1.00A 2bxkA-4lruA:
undetectable		 2bxkA-4lruA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lu4 PUTATIVE CELL
FILAMENTATION
PROTEIN

(Bartonella
quintana) 		PF02661
(Fic) 		4 SER A 127
PHE A 131
ALA A 135
LEU A 163
 None
 1.04A 2bxkA-4lu4A:
undetectable		 2bxkA-4lu4A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mbg CAAX
FARNESYLTRANSFERASE
BETA SUBUNIT RAM1

(Aspergillus
fumigatus) 		PF00432
(Prenyltrans) 		4 SER B 463
PHE B 465
ALA B 505
LEU B 263
 None
 1.07A 2bxkA-4mbgB:
undetectable		 2bxkA-4mbgB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mgq GLYCOSYL HYDROLASE
FAMILY 10

(Prevotella
bryantii) 		PF02018
(CBM_4_9) 		4 SER A 214
PHE A 228
ALA A 230
LEU A 178
 None
 1.13A 2bxkA-4mgqA:
undetectable		 2bxkA-4mgqA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0i GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF01425
(Amidase) 		4 PHE A 365
ALA A 427
LEU A 361
ASP A 150
 None
None
None
GLN  A 501 ( 4.7A)
 1.14A 2bxkA-4n0iA:
undetectable		 2bxkA-4n0iA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nn1 TRANSCRIPTIONAL
REGULATOR

(Mycobacterium
tuberculosis) 		PF00440
(TetR_N) 		4 SER A 101
PHE A  20
ALA A  16
ARG A  13
 None
 1.15A 2bxkA-4nn1A:
2.6		 2bxkA-4nn1A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nuz ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F2

(Streptococcus
pyogenes) 		no annotation 4 SER A 887
PHE A 825
ALA A 829
LEU A 792
 None
 1.15A 2bxkA-4nuzA:
4.0		 2bxkA-4nuzA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p56 PUTATIVE
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		4 PHE A  45
TRP A 274
LEU A 266
ASP A 236
 None
None
None
RMN  A 401 (-2.8A)
 0.89A 2bxkA-4p56A:
undetectable		 2bxkA-4p56A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pcs ALPHA-L-FUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01120
(Alpha_L_fucos) 		4 SER A 180
PHE A 228
ALA A 246
LEU A 250
 None
 1.17A 2bxkA-4pcsA:
undetectable		 2bxkA-4pcsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qme AMINOPEPTIDASE N

(Neisseria
meningitidis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 PHE A 827
ALA A 844
ARG A 803
ASP A 798
 None
 1.00A 2bxkA-4qmeA:
undetectable		 2bxkA-4qmeA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 SER A2204
PHE A2208
ALA A2152
LEU A2192
 None
 1.01A 2bxkA-4rh7A:
undetectable		 2bxkA-4rh7A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wgj BEPC PROTEIN

(Bartonella
tribocorum) 		PF02661
(Fic) 		4 SER A 127
PHE A 131
ALA A 135
LEU A 163
 None
 1.07A 2bxkA-4wgjA:
undetectable		 2bxkA-4wgjA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE

(Clitoria
ternatea) 		PF00201
(UDPGT) 		4 SER A 198
ALA A 206
LEU A 230
ASP A 114
 None
 1.14A 2bxkA-4whmA:
undetectable		 2bxkA-4whmA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afd N-ACETYLNEURAMINATE
LYASE

(Aliivibrio
salmonicida) 		PF00701
(DHDPS) 		4 TRP A  65
ALA A  62
LEU A  97
ASP A  27
 None
 1.15A 2bxkA-5afdA:
undetectable		 2bxkA-5afdA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ax7 PYRUVYL TRANSFERASE
1

(Schizosaccharomyces
pombe) 		PF04230
(PS_pyruv_trans) 		4 SER A 144
PHE A 151
ALA A  94
LEU A 153
 None
 1.13A 2bxkA-5ax7A:
undetectable		 2bxkA-5ax7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ema SORTING NEXIN-27

(Rattus
norvegicus) 		PF00595
(PDZ) 		4 SER A  82
PHE A  55
ARG A 122
LEU A 128
 None
 0.75A 2bxkA-5emaA:
undetectable		 2bxkA-5emaA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 PHE A 509
ALA A 589
ARG A 587
LEU A 574
 None
 1.07A 2bxkA-5ereA:
undetectable		 2bxkA-5ereA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		4 SER A 435
PHE A 437
ALA A 439
ARG A 440
 None
 1.08A 2bxkA-5gslA:
undetectable		 2bxkA-5gslA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4v GLUTAMATE--TRNA
LIGASE

(Xanthomonas
oryzae) 		no annotation 4 SER A 405
ALA A 391
ARG A 392
LEU A 428
 None
 0.71A 2bxkA-5h4vA:
undetectable		 2bxkA-5h4vA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpq ES8

(Chaetomium
thermophilum) 		no annotation 4 LYS t  83
ALA t 186
ARG t 185
LEU t  68
 U  2 259 ( 2.0A)
None
U  2 208 ( 1.6A)
None
 1.00A 2bxkA-5jpqt:
2.9		 2bxkA-5jpqt:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10

(Saccharomyces
cerevisiae) 		PF13519
(VWA_2) 		4 SER A  63
PHE A  65
ALA A   5
LEU A  98
 None
 1.12A 2bxkA-5ln1A:
undetectable		 2bxkA-5ln1A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtv EH DOMAIN-CONTAINING
PROTEIN 4

(Mus musculus) 		PF00350
(Dynamin_N)
PF16880
(EHD_N) 		4 PHE A 210
ALA A 182
LEU A  65
ASP A 173
 None
 1.11A 2bxkA-5mtvA:
undetectable		 2bxkA-5mtvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nnp N-TERMINAL
ACETYLTRANSFERASE-LI
KE PROTEIN

(Chaetomium
thermophilum) 		PF12569
(NARP1)
PF13432
(TPR_16) 		4 PHE A 305
ALA A 309
LEU A 341
ASP A 290
 None
None
None
GOL  B 201 (-4.3A)
 0.98A 2bxkA-5nnpA:
undetectable		 2bxkA-5nnpA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o16 AMBC

(Sorangium
cellulosum) 		no annotation 4 PHE A 290
ALA A 272
LEU A 221
ASP A 268
 None
 1.11A 2bxkA-5o16A:
undetectable		 2bxkA-5o16A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol8 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 SER A 172
PHE A 350
ALA A 354
LEU A 164
 None
 1.12A 2bxkA-5ol8A:
undetectable		 2bxkA-5ol8A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ufh LACI-TYPE
TRANSCRIPTIONAL
REGULATOR

(Bifidobacterium
animalis) 		PF13377
(Peripla_BP_3) 		4 SER A  73
ALA A  81
LEU A  67
ASP A 286
 None
None
None
GOL  A 401 ( 2.9A)
 1.13A 2bxkA-5ufhA:
undetectable		 2bxkA-5ufhA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uq1 SPEEDY PROTEIN A

(Homo sapiens) 		PF11357
(Spy1) 		4 PHE B 113
ALA B 111
ARG B 110
LEU B 167
 None
 1.13A 2bxkA-5uq1B:
undetectable		 2bxkA-5uq1B:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usc PREPHENATE
DEHYDROGENASE

(Bacillus
anthracis) 		PF02153
(PDH) 		4 PHE A 128
ALA A 118
LEU A  90
ASP A 191
 None
 1.07A 2bxkA-5uscA:
undetectable		 2bxkA-5uscA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wjc KINETOCHORE PROTEIN
MIS16

(Schizosaccharomyces
pombe) 		no annotation 4 SER A 343
ARG A 317
LEU A 297
ASP A 303
 None
 0.98A 2bxkA-5wjcA:
undetectable		 2bxkA-5wjcA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wrp PYRUVATE KINASE

(Mycobacterium
tuberculosis) 		no annotation 4 SER A 376
ALA A 384
ARG A 385
LEU A 392
 PO4  A 501 (-2.6A)
None
None
None
 1.01A 2bxkA-5wrpA:
undetectable		 2bxkA-5wrpA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xep CHITINASE-3-LIKE
PROTEIN 1

(Mus musculus) 		no annotation 4 SER A 334
ALA A 350
LEU A 380
ASP A 358
 None
 1.09A 2bxkA-5xepA:
undetectable		 2bxkA-5xepA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xn6 OS02G0668100 PROTEIN
OS07G0580900 PROTEIN

(Oryza sativa) 		PF00348
(polyprenyl_synt) 		4 SER A 122
ALA C 161
LEU A  33
ASP C 119
 None
 1.01A 2bxkA-5xn6A:
1.8		 2bxkA-5xn6A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwb 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Colwellia
psychrerythraea) 		PF00275
(EPSP_synthase) 		4 SER A  59
PHE A  82
ALA A 105
LEU A  34
 None
 1.13A 2bxkA-5xwbA:
undetectable		 2bxkA-5xwbA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zc2 -

(-) 		no annotation 4 SER B  69
PHE B  74
ALA B  35
ARG B  42
 FMN  B 401 (-3.4A)
None
None
None
 1.11A 2bxkA-5zc2B:
2.2		 2bxkA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ans UNCHARACTERIZED
PROTEIN

(Burkholderia
cenocepacia) 		PF06742
(DUF1214) 		4 ALA A 185
ARG A 106
LEU A 187
ASP A 144
 None
 1.15A 2bxkA-6ansA:
undetectable		 2bxkA-6ansA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c90 EXOSOME RNA HELICASE
MTR4,EXOSOME RNA
HELICASE MTR4

(Homo sapiens) 		no annotation 4 LYS A 198
PHE A 187
ALA A 171
LEU A 282
 None
 1.01A 2bxkA-6c90A:
2.3		 2bxkA-6c90A:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9m N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo sapiens) 		no annotation 4 LYS A   1
SER A   5
PHE A  14
ASP A 110
 None
 1.15A 2bxkA-6c9mA:
2.4		 2bxkA-6c9mA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cf8 LYTIC
TRANSGLYCOSYLASE

(Campylobacter
jejuni) 		no annotation 4 PHE A 188
ALA A 192
LEU A 224
ASP A 171
 None
 1.02A 2bxkA-6cf8A:
undetectable		 2bxkA-6cf8A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN

(Streptococcus
pyogenes;
Vibrio cholerae) 		no annotation 4 SER A 887
PHE A 825
ALA A 829
LEU A 792
 None
 1.11A 2bxkA-6en3A:
4.1		 2bxkA-6en3A:
8.72