SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXG_B_IBPB2002
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1al8 | GLYCOLATE OXIDASE (Spinaciaoleracea) |
PF01070(FMN_dh) | 5 | ALA A 246ALA A 247LEU A 65LEU A 228ALA A 151 | None | 1.01A | 2bxgB-1al8A:undetectable | 2bxgB-1al8A:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ciy | CRYIA(A) (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 6 | ALA A 165ALA A 164LEU A 103LEU A 141ALA A 144LEU A 199 | None | 1.43A | 2bxgB-1ciyA:1.0 | 2bxgB-1ciyA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ctt | CYTIDINE DEAMINASE (Escherichiacoli) |
PF00383(dCMP_cyt_deam_1)PF08211(dCMP_cyt_deam_2) | 5 | ALA A 61ALA A 88LEU A 249ALA A 31LEU A 57 | None | 0.95A | 2bxgB-1cttA:undetectable | 2bxgB-1cttA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dqs | PROTEIN(3-DEHYDROQUINATESYNTHASE) (Aspergillusnidulans) |
PF01761(DHQ_synthase) | 5 | LEU A 367LEU A 301ALA A 302LEU A 391VAL A 390 | None | 1.05A | 2bxgB-1dqsA:0.0 | 2bxgB-1dqsA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f6y | 5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE (Moorellathermoacetica) |
PF00809(Pterin_bind) | 6 | ALA A 228ALA A 226LEU A 223ALA A 218SER A 201VAL A 200 | None | 1.46A | 2bxgB-1f6yA:undetectable | 2bxgB-1f6yA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fc4 | 2-AMINO-3-KETOBUTYRATE CONENZYME ALIGASE (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | ARG A 382ALA A 383ALA A 386LEU A 345VAL A 352 | None | 0.74A | 2bxgB-1fc4A:undetectable | 2bxgB-1fc4A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kij | DNA GYRASE SUBUNIT B (Thermusthermophilus) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 5 | ALA A 348ALA A 345LEU A 340LEU A 327ALA A 270 | None | 1.06A | 2bxgB-1kijA:0.0 | 2bxgB-1kijA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyh | HYPOTHETICAL 29.9KDA PROTEIN INSIGY-CYDD INTERGENICREGION (Bacillussubtilis) |
PF01256(Carb_kinase) | 5 | ALA A 46ALA A 50LEU A 55LEU A 58ALA A 30 | None | 1.01A | 2bxgB-1kyhA:undetectable | 2bxgB-1kyhA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mtp | SERINE PROTEINASEINHIBITOR (SERPIN),CHAIN A (Thermobifidafusca) |
PF00079(Serpin) | 5 | LEU A 286LEU A 279ALA A 284LEU A 271VAL A 276 | None | 1.05A | 2bxgB-1mtpA:undetectable | 2bxgB-1mtpA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qcj | POKEWEED ANTIVIRALPROTEIN (Phytolaccaamericana) |
PF00161(RIP) | 5 | ALA A 27LEU A 23LEU A 71ALA A 178SER A 212 | None | 1.06A | 2bxgB-1qcjA:undetectable | 2bxgB-1qcjA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1soj | CGMP-INHIBITED3',5'-CYCLICPHOSPHODIESTERASE B (Homo sapiens) |
PF00233(PDEase_I) | 5 | ALA A 855ALA A 858LEU A 727ALA A 819VAL A 886 | None | 0.99A | 2bxgB-1sojA:undetectable | 2bxgB-1sojA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szi | MANNOSE-6-PHOSPHATERECEPTOR BINDINGPROTEIN 1 (Mus musculus) |
PF03036(Perilipin) | 6 | ALA A 265ALA A 269LEU A 273LEU A 405ALA A 401LEU A 262 | None | 1.39A | 2bxgB-1sziA:2.5 | 2bxgB-1sziA:17.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ALA A 21LEU A 139LEU A 155ALA A 158LYS A 159 | None | 1.02A | 2bxgB-1tf0A:47.3 | 2bxgB-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 9 | ARG A 209ALA A 210ALA A 213LEU A 331LEU A 347ALA A 350SER A 480LEU A 481VAL A 482 | DKA A1001 ( 4.6A)DKA A1002 (-3.3A)DKA A1001 ( 4.0A)NoneDKA A1002 ( 4.3A)DKA A1002 ( 3.8A)DKA A1002 (-3.4A)NoneDKA A1002 (-4.2A) | 0.40A | 2bxgB-1tf0A:47.3 | 2bxgB-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | LEU A 347LYS A 351SER A 480LEU A 481VAL A 482 | DKA A1002 ( 4.3A)DKA A1002 (-2.6A)DKA A1002 (-3.4A)NoneDKA A1002 (-4.2A) | 0.90A | 2bxgB-1tf0A:47.3 | 2bxgB-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ue8 | 367AA LONGHYPOTHETICALCYTOCHROME P450 (Sulfurisphaeratokodaii) |
PF00067(p450) | 5 | ALA A 323ALA A 327LEU A 331ALA A 222SER A 309 | HEM A 410 (-3.4A)NoneNoneNoneNone | 0.93A | 2bxgB-1ue8A:undetectable | 2bxgB-1ue8A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v19 | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermusthermophilus) |
PF00294(PfkB) | 5 | ALA A 7LEU A 113ALA A 117SER A 139LEU A 138 | None | 1.05A | 2bxgB-1v19A:undetectable | 2bxgB-1v19A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vz0 | CHROMOSOME-PARTITIONING PROTEIN SPO0J (Thermusthermophilus) |
PF02195(ParBc) | 5 | ALA A 175ALA A 178ALA A 164SER A 119VAL A 121 | None | 0.82A | 2bxgB-1vz0A:undetectable | 2bxgB-1vz0A:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zlj | DORMANCY SURVIVALREGULATOR (Mycobacteriumtuberculosis) |
PF00196(GerE) | 5 | ARG A 197ALA A 201ALA A 200LEU A 188LEU A 158 | None | 1.04A | 2bxgB-1zljA:undetectable | 2bxgB-1zljA:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fr1 | ERYTHROMYCINSYNTHASE, ERYAI (Saccharopolysporaerythraea) |
PF08659(KR) | 6 | ALA A1542LEU A1549LEU A1544ALA A1591LEU A1778VAL A1777 | None | 1.40A | 2bxgB-2fr1A:undetectable | 2bxgB-2fr1A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwr | DNA-BINDING RESPONSEREGULATOR MTRA (Mycobacteriumtuberculosis) |
PF00072(Response_reg)PF00486(Trans_reg_C) | 6 | ALA A 41ALA A 44LEU A 48LEU A 9ALA A 33LEU A 55 | None | 1.33A | 2bxgB-2gwrA:undetectable | 2bxgB-2gwrA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k3o | TUSP1 (Nephilaantipodiana) |
PF12042(RP1-2) | 5 | ALA A 82ALA A 85LEU A 107ALA A 45SER A 14 | None | 1.03A | 2bxgB-2k3oA:3.2 | 2bxgB-2k3oA:12.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o69 | IRON-UTILIZATIONPERIPLASMIC PROTEIN (Haemophilusinfluenzae) |
PF01547(SBP_bac_1) | 5 | ALA A 231ALA A 230LEU A 249SER A 236LEU A 233 | None | 1.03A | 2bxgB-2o69A:undetectable | 2bxgB-2o69A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oix | XANTHOMONAS OUTERPROTEIN D (Xanthomonaseuvesicatoria) |
PF02902(Peptidase_C48) | 5 | ALA A 425LEU A 451ALA A 446SER A 411LEU A 412 | None | 1.06A | 2bxgB-2oixA:undetectable | 2bxgB-2oixA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pa6 | ENOLASE (Methanocaldococcusjannaschii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ALA A 349LEU A 140LEU A 380ALA A 383VAL A 365 | None | 0.94A | 2bxgB-2pa6A:2.1 | 2bxgB-2pa6A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ptz | ENOLASE (Trypanosomabrucei) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ALA A 353LEU A 132LEU A 384ALA A 387VAL A 369 | None | 1.02A | 2bxgB-2ptzA:undetectable | 2bxgB-2ptzA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q9u | A-TYPE FLAVOPROTEIN (Giardiaintestinalis) |
no annotation | 5 | ALA A 344ALA A 312LEU A 277LEU A 399ALA A 395 | None | 1.04A | 2bxgB-2q9uA:undetectable | 2bxgB-2q9uA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rdy | BH0842 PROTEIN (Bacillushalodurans) |
PF14498(Glyco_hyd_65N_2) | 5 | ALA A 482LEU A 486LEU A 553ALA A 556LYS A 557 | None | 0.94A | 2bxgB-2rdyA:undetectable | 2bxgB-2rdyA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9m | POLYMERASE X (Deinococcusradiodurans) |
PF14520(HHH_5)PF14716(HHH_8) | 5 | ALA A 457LEU A 442ALA A 445LEU A 472VAL A 475 | None | 1.05A | 2bxgB-2w9mA:undetectable | 2bxgB-2w9mA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ypq | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE AROG (Mycobacteriumtuberculosis) |
PF01474(DAHP_synth_2) | 5 | ALA A 241LEU A 107ALA A 110LEU A 196VAL A 197 | TRP A1464 ( 3.9A)TRP A1464 ( 4.4A)TRP A1464 (-3.6A)NoneNone | 1.04A | 2bxgB-2ypqA:undetectable | 2bxgB-2ypqA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z55 | ARCHAERHODOPSIN-2 (Halobacteriumsp. AUS-2) |
PF01036(Bac_rhodopsin) | 5 | ALA A 212LEU A 216LEU A 193ALA A 189VAL A 196 | None | 0.91A | 2bxgB-2z55A:2.5 | 2bxgB-2z55A:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ady | DOTD (Legionellapneumophila) |
PF16816(DotD) | 5 | ALA A 99ALA A 101LEU A 41LEU A 128ALA A 83 | None | 1.07A | 2bxgB-3adyA:undetectable | 2bxgB-3adyA:12.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3azq | AMINOPEPTIDASE (Streptomycesmorookaense) |
PF00326(Peptidase_S9) | 6 | ALA A 636ALA A 639LEU A 658LEU A 586ALA A 616LEU A 533 | None | 1.01A | 2bxgB-3azqA:undetectable | 2bxgB-3azqA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3azq | AMINOPEPTIDASE (Streptomycesmorookaense) |
PF00326(Peptidase_S9) | 5 | ARG A 635ALA A 636ALA A 639LEU A 586ALA A 616 | None | 0.80A | 2bxgB-3azqA:undetectable | 2bxgB-3azqA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bed | PTS SYSTEM, IIACOMPONENT (Enterococcusfaecalis) |
PF03610(EIIA-man) | 5 | ALA A 97ALA A 100LEU A 111LEU A 5LEU A 18 | None | 0.93A | 2bxgB-3bedA:undetectable | 2bxgB-3bedA:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bjx | HALOCARBOXYLIC ACIDDEHALOGENASE DEHI (Pseudomonasputida) |
PF10778(DehI) | 6 | ALA A 65ALA A 68LEU A 72LEU A 119ALA A 228SER A 56 | None | 1.43A | 2bxgB-3bjxA:undetectable | 2bxgB-3bjxA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eh1 | PROTEIN TRANSPORTPROTEIN SEC24B (Homo sapiens) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | ALA A1023ALA A1026LEU A1042ALA A1041VAL A1078 | None | 0.98A | 2bxgB-3eh1A:undetectable | 2bxgB-3eh1A:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eo2 | NEUROEPITHELIALCELL-TRANSFORMINGGENE 1 PROTEIN (Homo sapiens) |
PF00621(RhoGEF) | 5 | LEU A 228LEU A 260ALA A 262LEU A 350VAL A 349 | None | 0.98A | 2bxgB-3eo2A:undetectable | 2bxgB-3eo2A:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eua | PUTATIVEFRUCTOSE-AMINOACID-6-PHOSPHATE DEGLYCASE (Bacillussubtilis) |
PF01380(SIS) | 5 | ALA A 96ALA A 93LEU A 114LEU A 79ALA A 105 | None | 1.01A | 2bxgB-3euaA:undetectable | 2bxgB-3euaA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fkr | L-2-KETO-3-DEOXYARABONATE DEHYDRATASE (Azospirillumbrasilense) |
PF00701(DHDPS) | 5 | ARG A 309ALA A 308LEU A 304LEU A 277VAL A 315 | None | 1.03A | 2bxgB-3fkrA:undetectable | 2bxgB-3fkrA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gqp | HEMOGLOBIN SUBUNITALPHA (Felis catus) |
PF00042(Globin) | 5 | ALA A 69LEU A 76SER A 84LEU A 136VAL A 135 | NoneNoneNoneHEM A 143 (-4.9A)None | 1.05A | 2bxgB-3gqpA:2.0 | 2bxgB-3gqpA:14.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic9 | DIHYDROLIPOAMIDEDEHYDROGENASE (Colwelliapsychrerythraea) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 6 | ALA A 60ALA A 57LEU A 54LEU A 193ALA A 189SER A 65 | None | 1.34A | 2bxgB-3ic9A:3.4 | 2bxgB-3ic9A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m16 | TRANSALDOLASE (Oleispiraantarctica) |
PF00923(TAL_FSA) | 5 | ALA A 244LEU A 266LEU A 12ALA A 11VAL A 18 | None | 0.99A | 2bxgB-3m16A:undetectable | 2bxgB-3m16A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n4h | PUTATIVE TAUTOMERASE (Corynebacteriumglutamicum) |
PF14552(Tautomerase_2) | 6 | ALA A 34ALA A 32LEU A 81ALA A 27LEU A 38VAL A 39 | PR7 A 1 ( 3.5A)NoneNoneNonePR7 A 1 ( 4.7A)PR7 A 1 ( 3.6A) | 1.21A | 2bxgB-3n4hA:undetectable | 2bxgB-3n4hA:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nhz | TWO COMPONENT SYSTEMTRANSCRIPTIONALREGULATOR MTRA (Mycobacteriumtuberculosis) |
PF00072(Response_reg) | 6 | ALA A 41ALA A 44LEU A 48LEU A 9ALA A 33LEU A 55 | None | 1.28A | 2bxgB-3nhzA:undetectable | 2bxgB-3nhzA:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nyq | MALONYL-COA LIGASE (Streptomycescoelicolor) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | ALA A 138LEU A 160ALA A 159LEU A 191VAL A 192 | None | 0.98A | 2bxgB-3nyqA:undetectable | 2bxgB-3nyqA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o6c | PYRIDOXINE5'-PHOSPHATESYNTHASE (Campylobacterjejuni) |
PF03740(PdxJ) | 5 | ALA A 79LEU A 80LEU A 117ALA A 120VAL A 124 | None | 0.97A | 2bxgB-3o6cA:undetectable | 2bxgB-3o6cA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3og4 | INTERLEUKIN-29 (Homo sapiens) |
PF15177(IL28A) | 5 | ALA A 34ALA A 37LEU A 91ALA A 90LEU A 83 | None | 0.89A | 2bxgB-3og4A:undetectable | 2bxgB-3og4A:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qp9 | TYPE I POLYKETIDESYNTHASE PIKAII (Streptomycesvenezuelae) |
PF08659(KR) | 5 | ALA A 244ALA A 247LEU A 258LEU A 289ALA A 296 | None | 0.97A | 2bxgB-3qp9A:undetectable | 2bxgB-3qp9A:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rij | SC_2CX5 (Thermusthermophilus) |
PF04073(tRNA_edit) | 5 | ALA A 34ALA A 37LEU A 27LEU A 136SER A 51 | None | 0.83A | 2bxgB-3rijA:undetectable | 2bxgB-3rijA:15.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1t | ASPARTOKINASE (Mycobacteriumtuberculosis) |
PF01842(ACT)PF13840(ACT_7) | 6 | ALA A 118LEU A 119LEU A 152ALA A 148LEU A 158VAL A 9 | None | 1.29A | 2bxgB-3s1tA:undetectable | 2bxgB-3s1tA:14.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1t | ASPARTOKINASE (Mycobacteriumtuberculosis) |
PF01842(ACT)PF13840(ACT_7) | 6 | ALA A 155ALA A 118LEU A 119LEU A 152ALA A 148VAL A 9 | None | 1.44A | 2bxgB-3s1tA:undetectable | 2bxgB-3s1tA:14.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swe | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Haemophilusinfluenzae) |
PF00275(EPSP_synthase) | 6 | ALA A 244ALA A 245LEU A 315LEU A 268ALA A 271VAL A 275 | None | 1.42A | 2bxgB-3sweA:undetectable | 2bxgB-3sweA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uog | ALCOHOLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 6 | ALA A 186ALA A 188LEU A 306ALA A 302LEU A 164VAL A 159 | None | 1.37A | 2bxgB-3uogA:undetectable | 2bxgB-3uogA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v7i | PUTATIVE POLYKETIDESYNTHASE (Streptomycescoelicolor) |
PF00195(Chal_sti_synt_N) | 5 | ALA A 370LEU A 310ALA A 359LEU A 389VAL A 243 | None | 0.95A | 2bxgB-3v7iA:undetectable | 2bxgB-3v7iA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcy | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Aliivibriofischeri) |
PF00275(EPSP_synthase) | 6 | ALA A 243ALA A 244LEU A 314LEU A 267ALA A 270VAL A 274 | None | 1.49A | 2bxgB-3vcyA:undetectable | 2bxgB-3vcyA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vh1 | UBIQUITIN-LIKEMODIFIER-ACTIVATINGENZYME ATG7 (Saccharomycescerevisiae) |
PF00899(ThiF)PF16420(ATG7_N) | 6 | ALA A 460LEU A 462LEU A 335ALA A 515SER A 340LEU A 329 | None | 1.45A | 2bxgB-3vh1A:undetectable | 2bxgB-3vh1A:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vre | HEMOGLOBIN SUBUNITALPHA (Mammuthusprimigenius) |
PF00042(Globin) | 6 | ALA A 69LEU A 73LEU A 76SER A 84LEU A 136VAL A 135 | None | 1.46A | 2bxgB-3vreA:2.1 | 2bxgB-3vreA:14.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zou | FARNESYLPYROPHOSPHATESYNTHASE (Pseudomonasaeruginosa) |
PF00348(polyprenyl_synt) | 5 | ALA A 68ALA A 69ALA A 16LEU A 124VAL A 123 | None | 0.99A | 2bxgB-3zouA:2.4 | 2bxgB-3zouA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4arx | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 6 | ALA A 165ALA A 164LEU A 103LEU A 141ALA A 144LEU A 199 | None | 1.46A | 2bxgB-4arxA:3.3 | 2bxgB-4arxA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ay7 | METHYLCOBALAMIN:COENZYME MMETHYLTRANSFERASE (Methanosarcinamazei) |
PF01208(URO-D) | 5 | ALA A 182ALA A 185LEU A 118LEU A 81ALA A 84 | None | 0.72A | 2bxgB-4ay7A:undetectable | 2bxgB-4ay7A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwk | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN-3 (Neurosporacrassa) |
no annotation | 5 | ALA A 406LEU A 423LEU A 396ALA A 395VAL A 506 | None | 1.07A | 2bxgB-4bwkA:undetectable | 2bxgB-4bwkA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fqd | NIKO PROTEIN (Streptomycestendae) |
PF00275(EPSP_synthase) | 6 | ALA A 45ALA A 43LEU A 228LEU A 201ALA A 204LEU A 111 | None | 1.35A | 2bxgB-4fqdA:undetectable | 2bxgB-4fqdA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g25 | PENTATRICOPEPTIDEREPEAT-CONTAININGPROTEIN AT2G32230,MITOCHONDRIAL (Arabidopsisthaliana) |
PF16953(PRORP)PF17177(PPR_long) | 5 | ALA A 227ALA A 230LEU A 218LEU A 252ALA A 251 | None | 1.00A | 2bxgB-4g25A:undetectable | 2bxgB-4g25A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4go5 | ASPARTOKINASE (Mycobacteriumtuberculosis) |
PF01842(ACT)PF13840(ACT_7) | 6 | ALA X 155ALA X 118LEU X 119LEU X 152ALA X 148VAL X 9 | None | 1.44A | 2bxgB-4go5X:undetectable | 2bxgB-4go5X:16.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpp | PROBABLE GLUTAMINESYNTHETASE (Pseudomonasaeruginosa) |
PF00120(Gln-synt_C)PF16952(Gln-synt_N_2) | 5 | ALA A 345ALA A 348LEU A 404LEU A 277ALA A 276 | None | 0.79A | 2bxgB-4hppA:undetectable | 2bxgB-4hppA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imr | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Agrobacteriumfabrum) |
PF13561(adh_short_C2) | 5 | ALA A 235LEU A 232LEU A 31ALA A 34VAL A 38 | None | 0.98A | 2bxgB-4imrA:undetectable | 2bxgB-4imrA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l7m | PUTATIVEUNCHARACTERIZEDPROTEIN (Thermococcusonnurineus) |
PF13646(HEAT_2) | 5 | ALA A 116LEU A 77SER A 140LEU A 139VAL A 138 | None | 1.07A | 2bxgB-4l7mA:2.1 | 2bxgB-4l7mA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lc3 | PUTATIVEUDP-4-AMINO-4-DEOXY-L-ARABINOSE--OXOGLUTARATEAMINOTRANSFERASE (Burkholderiacenocepacia) |
PF01041(DegT_DnrJ_EryC1) | 5 | ARG A 171LEU A 247LEU A 46ALA A 45VAL A 55 | None | 0.98A | 2bxgB-4lc3A:undetectable | 2bxgB-4lc3A:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nuf | MALTOSE ABCTRANSPORTERPERIPLASMIC PROTEIN,NUCLEAR RECEPTORSUBFAMILY 0 GROUP BMEMBER 2 CHIMERICCONSTRUCT (Escherichiacoli;Mus musculus) |
PF00104(Hormone_recep)PF13416(SBP_bac_8) | 5 | LEU A1156LEU A1103ALA A1104LEU A1066VAL A1065 | None | 1.03A | 2bxgB-4nufA:2.0 | 2bxgB-4nufA:22.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 8 | ALA A 210ALA A 213LEU A 331LEU A 347LYS A 351SER A 480LEU A 481VAL A 482 | NoneNPS A 602 (-3.3A)NoneNPS A 602 ( 4.2A)NoneNoneNoneNone | 0.74A | 2bxgB-4po0A:48.9 | 2bxgB-4po0A:74.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 7 | ARG A 209ALA A 210ALA A 213LEU A 331SER A 480LEU A 481VAL A 482 | NPS A 602 (-3.6A)NoneNPS A 602 (-3.3A)NoneNoneNoneNone | 0.87A | 2bxgB-4po0A:48.9 | 2bxgB-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q73 | PROLINEDEHYDROGENASE (Bradyrhizobiumdiazoefficiens) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 5 | ALA A 690ALA A 693LEU A 583LEU A 665ALA A 612 | None | 0.89A | 2bxgB-4q73A:undetectable | 2bxgB-4q73A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uaq | PROTEIN TRANSLOCASESUBUNIT SECA 2 (Mycobacteriumtuberculosis) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 5 | ALA A 76ALA A 78LEU A 95ALA A 98VAL A 35 | None | 1.00A | 2bxgB-4uaqA:undetectable | 2bxgB-4uaqA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8j | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 6 | ALA A 165ALA A 164LEU A 103LEU A 141ALA A 144LEU A 199 | None | 1.47A | 2bxgB-4w8jA:3.0 | 2bxgB-4w8jA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5af3 | VAPBC49 (Mycobacteriumtuberculosis) |
PF04255(DUF433) | 5 | ALA A 74ALA A 76LEU A 32LEU A 25ALA A 21 | None | 1.07A | 2bxgB-5af3A:undetectable | 2bxgB-5af3A:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cbm | M17 FAMILYAMINOPEPTIDASE (Plasmodiumfalciparum) |
PF00883(Peptidase_M17) | 5 | ALA A 313ALA A 314LEU A 357LEU A 407ALA A 410 | None | 1.01A | 2bxgB-5cbmA:undetectable | 2bxgB-5cbmA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwc | DESIGNED HELICALREPEAT PROTEIN (syntheticconstruct) |
no annotation | 5 | ALA A 95ALA A 98ALA A 145LEU A 106VAL A 105 | None | 1.00A | 2bxgB-5cwcA:3.7 | 2bxgB-5cwcA:18.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 7 | ALA A 209ALA A 212LEU A 330LEU A 346ALA A 349SER A 479LEU A 480 | CZE A 613 ( 4.4A)CZE A 613 ( 3.7A)CZE A 613 ( 4.2A)CZE A 613 ( 3.8A)CZE A 613 ( 4.7A)NoneNone | 0.60A | 2bxgB-5dqfA:49.6 | 2bxgB-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 7 | ALA A 209LEU A 330LEU A 346ALA A 349LYS A 350SER A 479LEU A 480 | CZE A 613 ( 4.4A)CZE A 613 ( 4.2A)CZE A 613 ( 3.8A)CZE A 613 ( 4.7A)CZE A 613 (-4.1A)NoneNone | 0.88A | 2bxgB-5dqfA:49.6 | 2bxgB-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | ARG A 208ALA A 209ALA A 212LEU A 330LEU A 346 | CZE A 613 ( 3.5A)CZE A 613 ( 4.4A)CZE A 613 ( 3.7A)CZE A 613 ( 4.2A)CZE A 613 ( 3.8A) | 0.83A | 2bxgB-5dqfA:49.6 | 2bxgB-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ed7 | TEGUMENT PROTEINUL21 (Humanalphaherpesvirus1) |
PF03252(Herpes_UL21) | 5 | ALA A 401ALA A 404LEU A 459LEU A 435VAL A 520 | None | 1.02A | 2bxgB-5ed7A:2.4 | 2bxgB-5ed7A:18.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 9 | ALA A 210ALA A 213LEU A 331LEU A 347ALA A 350LYS A 351SER A 480LEU A 481VAL A 482 | None | 0.80A | 2bxgB-5ghkA:46.4 | 2bxgB-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hws | 2-DEHYDROPANTOATE2-REDUCTASE (Thermococcuskodakarensis) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | LEU A 290ALA A 293LYS A 294LEU A 194VAL A 193 | None | 0.98A | 2bxgB-5hwsA:undetectable | 2bxgB-5hwsA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jp3 | XANTHOMONAS OUTERPROTEIN D (Xanthomonaseuvesicatoria) |
PF02902(Peptidase_C48) | 5 | ALA A 425LEU A 451ALA A 446SER A 411LEU A 412 | None | 1.07A | 2bxgB-5jp3A:undetectable | 2bxgB-5jp3A:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1s | OXIDOREDUCTASE,ZINC-BINDINGDEHYDROGENASE FAMILY (Myxococcusxanthus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 175LEU A 181LEU A 207ALA A 210VAL A 215 | None | 1.04A | 2bxgB-5k1sA:undetectable | 2bxgB-5k1sA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2p | ARYLESTERASE (Sulfolobussolfataricus) |
PF07859(Abhydrolase_3) | 5 | ALA A 85ALA A 157LEU A 161ALA A 125LEU A 88 | None | 0.86A | 2bxgB-5l2pA:undetectable | 2bxgB-5l2pA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mr6 | XIAF PROTEIN (Streptomycessp.) |
PF08028(Acyl-CoA_dh_2) | 6 | ALA A 236ALA A 235LEU A 317LEU A 307ALA A 310VAL A 68 | None | 1.08A | 2bxgB-5mr6A:undetectable | 2bxgB-5mr6A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5msw | THIOESTER REDUCTASEDOMAIN-CONTAININGPROTEIN (Segniliparusrugosus) |
PF00501(AMP-binding)PF00550(PP-binding) | 5 | ALA A 216ALA A 217LEU A 198LEU A 182ALA A 185 | None | 1.01A | 2bxgB-5mswA:undetectable | 2bxgB-5mswA:19.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 9 | ARG A 208ALA A 209ALA A 212LEU A 330LEU A 346ALA A 349SER A 479LEU A 480VAL A 481 | None | 0.58A | 2bxgB-5oriA:49.1 | 2bxgB-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ux5 | BIFUNCTIONAL PROTEINPROLINE UTILIZATIONA (PUTA) (Corynebacteriumfreiburgense) |
PF00171(Aldedh)PF01619(Pro_dh) | 5 | ALA A 625ALA A 628LEU A 529LEU A 600ALA A 558 | None | 0.71A | 2bxgB-5ux5A:undetectable | 2bxgB-5ux5A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyl | INNER TEGUMENTPROTEIN (Humanalphaherpesvirus1) |
PF03970(Herpes_UL37_1) | 5 | ALA A 104ALA A 107LEU A 88LEU A 152ALA A 151 | None | 0.88A | 2bxgB-5vylA:undetectable | 2bxgB-5vylA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wi5 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE 1 (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 5 | ALA A 245ALA A 247LEU A 293LEU A 385VAL A 386 | None | 1.05A | 2bxgB-5wi5A:undetectable | 2bxgB-5wi5A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wy4 | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
no annotation | 5 | ARG A 319LEU A 358ALA A 329LEU A 296VAL A 297 | None | 1.04A | 2bxgB-5wy4A:undetectable | 2bxgB-5wy4A:8.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6o | DNA DAMAGECHECKPOINT PROTEINLCD1 (Saccharomycescerevisiae) |
no annotation | 5 | ALA G 318LEU G 275SER G 381LEU G 379VAL G 378 | None | 1.02A | 2bxgB-5x6oG:undetectable | 2bxgB-5x6oG:9.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xpz | FERMITIN FAMILYHOMOLOG 2 (Mus musculus) |
PF00373(FERM_M) | 5 | ALA A 86ALA A 88LEU A 90LEU A 20VAL A 35 | None | 1.02A | 2bxgB-5xpzA:3.6 | 2bxgB-5xpzA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxo | PERIPLASMICBETA-GLUCOSIDASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | ALA A 513ALA A 464SER A 446LEU A 447VAL A 448 | None | 0.81A | 2bxgB-5xxoA:2.3 | 2bxgB-5xxoA:8.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | DNA-DEPENDENTPROTEIN KINASECATALYTIC SUBUNIT (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08163(NUC194) | 5 | ALA C3987ALA C3990ALA C3780SER C3906LEU C3910 | None | 0.99A | 2bxgB-5y3rC:undetectable | 2bxgB-5y3rC:9.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 7 | ALA A 210LEU A 331LEU A 347ALA A 350SER A 480LEU A 481VAL A 482 | None | 0.67A | 2bxgB-5yxeA:46.8 | 2bxgB-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 8 | ARG A 209ALA A 210ALA A 213LEU A 331LEU A 347ALA A 350LEU A 481VAL A 482 | None | 0.54A | 2bxgB-5yxeA:46.8 | 2bxgB-5yxeA:11.11 |