SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXF_B_DZPB2001
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b1y | PROTEIN(BETA-AMYLASE) (Hordeum vulgare) |
PF01373(Glyco_hydro_14) | 5 | ILE A 294ASN A 338LEU A 411VAL A 375LEU A 365 | None | 1.15A | 2bxfB-1b1yA:undetectable | 2bxfB-1b1yA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6v | CHIMERIC GERMLINEPRECURSOR OFOXY-COPE CATALYTICANTIBODY AZ-28(LIGHT CHAIN) (Homo sapiens;Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | TYR L 86LEU L 104GLU L 79LEU L 78ARG L 61 | NoneNone CD L 501 (-2.4A)None CD L 504 ( 4.3A) | 1.33A | 2bxfB-1d6vL:undetectable | 2bxfB-1d6vL:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jm7 | BREAST CANCER TYPE 1SUSCEPTIBILITYPROTEIN (Homo sapiens) |
PF00097(zf-C3HC4) | 5 | ILE A 21LEU A 87VAL A 83GLU A 23LEU A 30 | None | 1.33A | 2bxfB-1jm7A:undetectable | 2bxfB-1jm7A:11.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7g | GDP-D-MANNOSE-4,6-DEHYDRATASE (Arabidopsisthaliana) |
PF16363(GDP_Man_Dehyd) | 5 | ILE A 70LEU A 84VAL A 55GLU A 46LEU A 49 | None | 1.03A | 2bxfB-1n7gA:undetectable | 2bxfB-1n7gA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7k | DEOXYRIBOSE-PHOSPHATE ALDOLASE (Aeropyrumpernix) |
PF01791(DeoC) | 5 | LEU A 29LEU A 67VAL A 73CYH A 53GLU A 45 | None | 1.30A | 2bxfB-1n7kA:undetectable | 2bxfB-1n7kA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pem | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2ALPHA CHAIN (Salmonellaenterica) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF08343(RNR_N) | 5 | LEU A 512ASN A 580LEU A 442GLU A 436ARG A 440 | None | 1.32A | 2bxfB-1pemA:2.7 | 2bxfB-1pemA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qap | QUINOLINIC ACIDPHOSPHORIBOSYLTRANSFERASE (Salmonellaenterica) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ILE A 78LEU A 106VAL A 85GLU A 74LEU A 87 | None | 1.34A | 2bxfB-1qapA:undetectable | 2bxfB-1qapA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r3n | BETA-ALANINESYNTHASE (Lachanceakluyveri) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | LEU A 440ILE A 443LEU A 134VAL A 153LEU A 137 | None | 1.27A | 2bxfB-1r3nA:undetectable | 2bxfB-1r3nA:19.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 9 | ILE A 388ASN A 391PHE A 403TYR A 411LEU A 430VAL A 433GLU A 450LEU A 453ARG A 485 | None | 0.87A | 2bxfB-1tf0A:47.4 | 2bxfB-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | LEU A 387ILE A 388ASN A 391PHE A 403GLU A 450ARG A 485 | None | 0.93A | 2bxfB-1tf0A:47.4 | 2bxfB-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vaj | HYPOTHETICAL PROTEINPH0010 (Pyrococcushorikoshii) |
PF01871(AMMECR1) | 5 | PHE A 191LEU A 13VAL A 110GLU A 43LEU A 75 | None | 1.32A | 2bxfB-1vajA:undetectable | 2bxfB-1vajA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1woz | 177AA LONG CONSERVEDHYPOTHETICAL PROTEIN(ST1454) (Sulfurisphaeratokodaii) |
PF01923(Cob_adeno_trans) | 5 | ILE A 77PHE A 27LEU A 34GLU A 60LEU A 61 | None | 1.34A | 2bxfB-1wozA:2.2 | 2bxfB-1wozA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xxi | DNA POLYMERASE IIISUBUNIT GAMMA (Escherichiacoli) |
PF12169(DNA_pol3_gamma3)PF13177(DNA_pol3_delta2) | 5 | LEU B 218LEU B 203VAL B 232GLU B 194LEU B 191 | None | 1.25A | 2bxfB-1xxiB:3.5 | 2bxfB-1xxiB:20.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ysx | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ILE A 388ASN A 391CYH A 392PHE A 403TYR A 411 | 4EB A1000 ( 4.6A)4EB A1000 (-3.5A)4EB A1000 (-3.2A)4EB A1000 ( 4.1A)4EB A1000 (-3.3A) | 0.81A | 2bxfB-1ysxA:4.8 | 2bxfB-1ysxA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ysx | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | LEU A 387ASN A 391CYH A 392PHE A 403TYR A 411 | None4EB A1000 (-3.5A)4EB A1000 (-3.2A)4EB A1000 ( 4.1A)4EB A1000 (-3.3A) | 0.93A | 2bxfB-1ysxA:4.8 | 2bxfB-1ysxA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z68 | FIBROBLASTACTIVATION PROTEIN,ALPHA SUBUNIT (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | ILE A 367ASN A 399PHE A 401TYR A 450GLU A 396 | None | 1.10A | 2bxfB-1z68A:2.0 | 2bxfB-1z68A:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zch | HYPOTHETICALOXIDOREDUCTASE YCND (Bacillussubtilis) |
PF00881(Nitroreductase) | 5 | ILE A 49LEU A 63CYH A 80LEU A 148ARG A 56 | None | 1.28A | 2bxfB-1zchA:undetectable | 2bxfB-1zchA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cd0 | PROTEIN (BENCE-JONESPROTEIN WIL, AVARIABLE DOMAIN FROMLAMBDA-6 TYPEIMMUNOGLOBULIN LIGHTCHAIN) (Homo sapiens) |
PF07686(V-set) | 5 | TYR A 86LEU A 104VAL A 106LEU A 78ARG A 61 | None | 1.21A | 2bxfB-2cd0A:undetectable | 2bxfB-2cd0A:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ef4 | ARGINASE (Thermusthermophilus) |
PF00491(Arginase) | 5 | LEU A 75VAL A 142GLU A 153LEU A 151ARG A 71 | None | 1.23A | 2bxfB-2ef4A:undetectable | 2bxfB-2ef4A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fqx | MEMBRANE LIPOPROTEINTMPC (Treponemapallidum) |
PF02608(Bmp) | 5 | ASN A 125LEU A 130VAL A 293GLU A 289LEU A 288 | None | 1.31A | 2bxfB-2fqxA:undetectable | 2bxfB-2fqxA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hj0 | PUTATIVE CITRATELYASE, ALFA SUBUNIT (Streptococcusmutans) |
PF04223(CitF) | 5 | PHE A 274VAL A 322GLU A 319LEU A 316ARG A 292 | None | 1.18A | 2bxfB-2hj0A:undetectable | 2bxfB-2hj0A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i88 | COLICIN-E1 (Escherichiacoli) |
PF01024(Colicin) | 5 | ILE A 451PHE A 393LEU A 504VAL A 500LEU A 483 | None | 1.32A | 2bxfB-2i88A:2.1 | 2bxfB-2i88A:16.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3m | PROLYL-TRNASYNTHETASE (Enterococcusfaecalis) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF04073(tRNA_edit) | 5 | ILE A 406TYR A 40VAL A 20GLU A 218ARG A 151 | NoneNoneNoneNoneATP A 701 (-2.5A) | 1.29A | 2bxfB-2j3mA:undetectable | 2bxfB-2j3mA:24.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8x | URACIL-DNAGLYCOSYLASE (Humangammaherpesvirus4) |
PF03167(UDG) | 5 | LEU A 200ILE A 201LEU A 148VAL A 86LEU A 88 | None | 1.06A | 2bxfB-2j8xA:undetectable | 2bxfB-2j8xA:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nym | SERINE/THREONINE-PROTEIN PHOSPHATASE 2ACATALYTIC SUBUNITALPHA ISOFORM (Homo sapiens) |
PF00149(Metallophos) | 5 | LEU C 170ILE C 174LEU C 158VAL C 45LEU C 177 | None | 1.22A | 2bxfB-2nymC:undetectable | 2bxfB-2nymC:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p67 | LAO/AO TRANSPORTSYSTEM KINASE (Escherichiacoli) |
PF03308(ArgK) | 5 | ILE A 246LEU A 196VAL A 198GLU A 248LEU A 236 | None | 1.30A | 2bxfB-2p67A:undetectable | 2bxfB-2p67A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qsr | TRANSCRIPTION-REPAIRCOUPLING FACTOR (Streptococcuspneumoniae) |
PF03461(TRCF) | 5 | ILE A1160PHE A1099LEU A1080VAL A1083GLU A1159 | None | 1.09A | 2bxfB-2qsrA:undetectable | 2bxfB-2qsrA:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v0o | FCH DOMAIN ONLYPROTEIN 2 (Homo sapiens) |
PF00611(FCH) | 5 | ILE A 227LEU A 97GLU A 46LEU A 94ARG A 42 | None | 1.22A | 2bxfB-2v0oA:3.5 | 2bxfB-2v0oA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu5 | SUCCINATEDEHYDROGENASEFLAVOPROTEIN SUBUNIT (Escherichiacoli) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | LEU A 24LEU A 145GLU A 98LEU A 99ARG A 21 | None | 1.25A | 2bxfB-2wu5A:2.0 | 2bxfB-2wu5A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yjt | ATP-DEPENDENT RNAHELICASE SRMB (Escherichiacoli) |
PF00271(Helicase_C) | 5 | LEU D 232LEU D 239GLU D 263LEU D 264ARG D 260 | None | 1.31A | 2bxfB-2yjtD:undetectable | 2bxfB-2yjtD:13.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzm | D-ALANINE--D-ALANINELIGASE (Thermusthermophilus) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | LEU A 298LEU A 242VAL A 250GLU A 199LEU A 198 | None | 1.22A | 2bxfB-2yzmA:undetectable | 2bxfB-2yzmA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cb0 | 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE (Brucellamelitensis) |
PF01613(Flavin_Reduct) | 5 | LEU A 60ILE A 59CYH A 131VAL A 33LEU A 46 | NoneNoneNoneNoneFMN A 200 (-3.8A) | 1.12A | 2bxfB-3cb0A:undetectable | 2bxfB-3cb0A:12.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cfi | TYPE II SECRETORYPATHWAY, PSEUDOPILINEPSJ (Vibriovulnificus) |
PF11612(T2SSJ) | 5 | ASN B 86LEU B 120VAL B 145GLU B 175LEU B 176 | None | 1.25A | 2bxfB-3cfiB:undetectable | 2bxfB-3cfiB:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cue | TRANSPORT PROTEINPARTICLE 18 KDASUBUNIT (Saccharomycescerevisiae) |
PF04099(Sybindin) | 6 | LEU C 51TYR C 75LEU C 91VAL C 89CYH C 81LEU C 44 | None | 1.19A | 2bxfB-3cueC:undetectable | 2bxfB-3cueC:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cxm | URACIL-DNAGLYCOSYLASE (Leishmanianaiffi) |
PF03167(UDG) | 5 | LEU A 318ILE A 319LEU A 264VAL A 201LEU A 203 | None | 1.11A | 2bxfB-3cxmA:undetectable | 2bxfB-3cxmA:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3etc | AMP-BINDING PROTEIN (Methanosarcinaacetivorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | ILE A 494LEU A 514VAL A 518GLU A 468LEU A 471 | None | 1.04A | 2bxfB-3etcA:undetectable | 2bxfB-3etcA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxh | INTEGRON GENECASSETTE PROTEINHFX_CASS2 (unculturedbacterium) |
no annotation | 5 | LEU A 35TYR A 49LEU A 20CYH A 103LEU A 96 | None | 1.32A | 2bxfB-3fxhA:2.2 | 2bxfB-3fxhA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hl0 | MALEYLACETATEREDUCTASE (Agrobacteriumfabrum) |
PF00465(Fe-ADH) | 5 | ILE A 27CYH A 88LEU A 92VAL A 37LEU A 50 | None | 0.96A | 2bxfB-3hl0A:undetectable | 2bxfB-3hl0A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ho6 | TOXIN A (Clostridioidesdifficile) |
PF11713(Peptidase_C80) | 5 | ILE A 42TYR A 171LEU A 175VAL A 153GLU A 134 | None | 1.26A | 2bxfB-3ho6A:undetectable | 2bxfB-3ho6A:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ifs | GLUCOSE-6-PHOSPHATEISOMERASE (Bacillusanthracis) |
PF00342(PGI) | 5 | LEU A 162ILE A 158LEU A 115VAL A 117LEU A 129 | None | 1.25A | 2bxfB-3ifsA:undetectable | 2bxfB-3ifsA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iqt | SIGNAL TRANSDUCTIONHISTIDINE-PROTEINKINASE BARA (Escherichiacoli) |
PF01627(Hpt) | 5 | LEU A 878ILE A 882LEU A 837VAL A 840LEU A 863 | None | 1.08A | 2bxfB-3iqtA:2.9 | 2bxfB-3iqtA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kds | CELL DIVISIONPROTEIN FTSH (Thermotogamaritima) |
PF00004(AAA)PF01434(Peptidase_M41) | 5 | ILE E 301LEU E 210VAL E 214GLU E 175LEU E 173 | None | 0.92A | 2bxfB-3kdsE:2.4 | 2bxfB-3kdsE:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ljf | IRON SUPEROXIDEDISMUTASE (Pseudoalteromonashaloplanktis) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 5 | ILE A 11TYR A 76LEU A 80GLU A 15LEU A 14 | None | 1.31A | 2bxfB-3ljfA:undetectable | 2bxfB-3ljfA:14.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nek | NITROGENREPRESSOR-LIKEPROTEIN MJ0159 (Methanocaldococcusjannaschii) |
PF01995(DUF128) | 5 | LEU A 410VAL A 408GLU A 470LEU A 469ARG A 466 | None | 1.34A | 2bxfB-3nekA:undetectable | 2bxfB-3nekA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o7b | RIBOSOME BIOGENESISNEP1 RNAMETHYLTRANSFERASE (Archaeoglobusfulgidus) |
PF03587(EMG1) | 5 | LEU A 127ILE A 128ASN A 95VAL A 82LEU A 73 | None | 1.26A | 2bxfB-3o7bA:undetectable | 2bxfB-3o7bA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ob8 | BETA-GALACTOSIDASE (Kluyveromyceslactis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N) | 5 | LEU A 348ILE A 347PHE A 580TYR A 639GLU A 302 | None | 1.34A | 2bxfB-3ob8A:undetectable | 2bxfB-3ob8A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3om8 | PROBABLE HYDROLASE (Pseudomonasaeruginosa) |
PF00561(Abhydrolase_1) | 5 | LEU A 15LEU A 100VAL A 104LEU A 77ARG A 60 | NoneEDO A 266 (-3.7A)NoneNoneNone | 1.18A | 2bxfB-3om8A:undetectable | 2bxfB-3om8A:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqv | GERANYLGERANYLPYROPHOSPHATESYNTHASE (Corynebacteriumglutamicum) |
PF00348(polyprenyl_synt) | 5 | LEU A 286LEU A 207VAL A 211LEU A 197ARG A 282 | None | 1.30A | 2bxfB-3qqvA:2.4 | 2bxfB-3qqvA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tlp | PROTEIN POLYBROMO-1 (Homo sapiens) |
PF00439(Bromodomain) | 5 | LEU A 494VAL A 498CYH A 511GLU A 583LEU A 586 | None | 1.20A | 2bxfB-3tlpA:3.3 | 2bxfB-3tlpA:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr7 | URACIL-DNAGLYCOSYLASE (Coxiellaburnetii) |
PF03167(UDG) | 5 | LEU A 176ILE A 177LEU A 124VAL A 62LEU A 64 | None | 1.10A | 2bxfB-3tr7A:undetectable | 2bxfB-3tr7A:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vth | HYDROGENASEMATURATION FACTOR (Caldanaerobactersubterraneus) |
PF00708(Acylphosphatase)PF01300(Sua5_yciO_yrdC)PF07503(zf-HYPF) | 5 | LEU A 684ILE A 688LEU A 699VAL A 697LEU A 717 | None | 1.32A | 2bxfB-3vthA:undetectable | 2bxfB-3vthA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdg | URACIL-DNAGLYCOSYLASE (Staphylococcusaureus) |
PF03167(UDG) | 5 | LEU A 167ILE A 168LEU A 115VAL A 54LEU A 56 | None | 1.05A | 2bxfB-3wdgA:undetectable | 2bxfB-3wdgA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x1o | ROQUIN-1 (Homo sapiens) |
no annotation | 5 | LEU A 307LEU A 249VAL A 245LEU A 204ARG A 280 | None | 1.34A | 2bxfB-3x1oA:undetectable | 2bxfB-3x1oA:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4buh | CLONE M0418 SCFV (Homo sapiens) |
PF07686(V-set) | 5 | TYR A 228LEU A 248VAL A 250LEU A 220ARG A 203 | None | 1.33A | 2bxfB-4buhA:undetectable | 2bxfB-4buhA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cad | RAS AND A-FACTORCONVERTING ENZYME 1,RCE1 (Methanococcusmaripaludis) |
PF02517(Abi) | 5 | LEU C 229ILE C 230ASN C 233VAL C 96LEU C 92 | NoneNoneBOG C 301 (-3.0A)NoneNone | 1.32A | 2bxfB-4cadC:2.8 | 2bxfB-4cadC:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ckr | EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1 (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | ILE A 780CYH A 772LEU A 839VAL A 836LEU A 743 | None | 1.27A | 2bxfB-4ckrA:undetectable | 2bxfB-4ckrA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2u | PHO RADA INTEIN (Pyrococcushorikoshii) |
PF14890(Intein_splicing) | 5 | LEU A 76ILE A 77LEU A 170VAL A 95LEU A 87 | None | 1.02A | 2bxfB-4e2uA:undetectable | 2bxfB-4e2uA:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gx0 | TRKA DOMAIN PROTEIN (Geobactersulfurreducens) |
PF02080(TrkA_C)PF02254(TrkA_N)PF07885(Ion_trans_2) | 5 | PHE A 136VAL A 178GLU A 124LEU A 125ARG A 192 | None | 1.29A | 2bxfB-4gx0A:3.1 | 2bxfB-4gx0A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hh1 | APPA PROTEIN (Rhodobactersphaeroides) |
PF04940(BLUF) | 5 | LEU A 91ILE A 90CYH A 19GLU A 89ARG A 22 | None | 1.22A | 2bxfB-4hh1A:undetectable | 2bxfB-4hh1A:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iqh | DYSFERLIN (Homo sapiens) |
PF00168(C2) | 5 | LEU A 94PHE A 103LEU A 67VAL A 123LEU A 3 | None | 1.34A | 2bxfB-4iqhA:undetectable | 2bxfB-4iqhA:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iyo | CYSTATHIONINEGAMMA-LYASE-LIKEPROTEIN, LYS201AMODIFIED (Xanthomonasoryzae) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU B 118PHE B 133VAL B 105LEU B 129ARG B 123 | None | 1.33A | 2bxfB-4iyoB:undetectable | 2bxfB-4iyoB:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jip | GTN REDUCTASE (Agrobacteriumtumefaciens) |
PF00724(Oxidored_FMN) | 5 | ILE A 229PHE A 289LEU A 248VAL A 252LEU A 189 | None | 1.26A | 2bxfB-4jipA:undetectable | 2bxfB-4jipA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq8 | CYTOCHROME P450 19A1 (Homo sapiens) |
PF00067(p450) | 5 | ILE A 132ASN A 135LEU A 122CYH A 299ARG A 115 | HEM A 601 (-3.8A)NoneNoneNoneHEM A 601 ( 2.6A) | 1.31A | 2bxfB-4kq8A:undetectable | 2bxfB-4kq8A:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m4z | SRC-LIKE-ADAPTER 2 (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 5 | LEU A 110ASN A 113TYR A 96LEU A 119GLU A 106 | None | 1.33A | 2bxfB-4m4zA:undetectable | 2bxfB-4m4zA:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n1a | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 5 | LEU A 944ASN A 942VAL A 940GLU A 954ARG A 947 | None | 1.31A | 2bxfB-4n1aA:undetectable | 2bxfB-4n1aA:21.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 9 | LEU A 387ASN A 391PHE A 403TYR A 411LEU A 430VAL A 433GLU A 450LEU A 453ARG A 485 | NPS A 601 ( 4.7A)NPS A 601 (-4.3A)NoneNPS A 601 (-4.3A)NPS A 601 ( 4.0A)NoneNoneNPS A 601 (-4.7A)None | 0.68A | 2bxfB-4po0A:49.5 | 2bxfB-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qik | ROQUIN-1 (Homo sapiens) |
no annotation | 5 | LEU A 307LEU A 249VAL A 245LEU A 204ARG A 280 | None | 1.33A | 2bxfB-4qikA:2.5 | 2bxfB-4qikA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qus | ACETYLTRANSFERASEYPEA (Escherichiacoli) |
PF00583(Acetyltransf_1) | 5 | ILE A 105LEU A 44VAL A 58GLU A 92LEU A 91 | None | 1.34A | 2bxfB-4qusA:undetectable | 2bxfB-4qusA:13.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5q | CRISPR-ASSOCIATEDEXONUCLEASE, CAS4FAMILY (Pyrobaculumcalidifontis) |
PF01930(Cas_Cas4) | 5 | ILE A 133TYR A 97LEU A 101VAL A 107LEU A 3 | None | 1.18A | 2bxfB-4r5qA:undetectable | 2bxfB-4r5qA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z31 | ROQUIN-2 (Homo sapiens) |
no annotation | 5 | LEU A 304LEU A 246VAL A 242LEU A 201ARG A 277 | None | 1.32A | 2bxfB-4z31A:2.7 | 2bxfB-4z31A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zlc | ROQUIN-2 (Homo sapiens) |
no annotation | 5 | LEU A 304LEU A 246VAL A 242LEU A 201ARG A 277 | None | 1.29A | 2bxfB-4zlcA:2.2 | 2bxfB-4zlcA:13.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 8 | ASN A 390PHE A 402TYR A 410LEU A 429VAL A 432GLU A 449LEU A 452ARG A 484 | None | 0.78A | 2bxfB-5dqfA:50.1 | 2bxfB-5dqfA:76.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 7 | LEU A 386ASN A 390PHE A 402TYR A 410VAL A 432GLU A 449ARG A 484 | None | 0.73A | 2bxfB-5dqfA:50.1 | 2bxfB-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dzs | SHIKIMATEDEHYDROGENASE(NADP(+)) (Clostridioidesdifficile) |
PF08501(Shikimate_dh_N) | 5 | LEU A 164ILE A 163LEU A 124VAL A 122GLU A 169 | None | 1.23A | 2bxfB-5dzsA:undetectable | 2bxfB-5dzsA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5f | ROQUIN-1 (Mus musculus) |
no annotation | 5 | LEU A 307LEU A 249VAL A 245LEU A 204ARG A 280 | None | 1.29A | 2bxfB-5f5fA:undetectable | 2bxfB-5f5fA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fbu | PHOSPHOENOLPYRUVATESYNTHASE (Listeriamonocytogenes) |
PF00391(PEP-utilizers)PF01326(PPDK_N) | 5 | LEU A 604ILE A 605ASN A 608TYR A 833LEU A 528 | None | 1.08A | 2bxfB-5fbuA:3.1 | 2bxfB-5fbuA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fwj | HISTONE DEMETHYLASEJARID1C (Homo sapiens) |
PF02373(JmjC)PF02375(JmjN)PF02928(zf-C5HC2) | 5 | ILE A 515LEU A 576VAL A 537GLU A 546LEU A 545 | None | 1.21A | 2bxfB-5fwjA:undetectable | 2bxfB-5fwjA:20.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 8 | ASN A 391PHE A 403TYR A 411LEU A 430VAL A 433GLU A 450LEU A 453ARG A 485 | None | 0.76A | 2bxfB-5ghkA:46.6 | 2bxfB-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 6 | LEU A 387ASN A 391TYR A 411VAL A 433GLU A 450ARG A 485 | None | 0.95A | 2bxfB-5ghkA:46.6 | 2bxfB-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hr4 | MMEI (Methylophilusmethylotrophus) |
no annotation | 5 | ILE C 321ASN C 368LEU C 426GLU C 376ARG C 375 | NoneSFG C1002 (-4.1A)NoneNoneNone | 1.29A | 2bxfB-5hr4C:undetectable | 2bxfB-5hr4C:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jk6 | PHENYLALANINE-4-HYDROXYLASE (Dictyosteliumdiscoideum) |
PF00351(Biopterin_H) | 5 | LEU A 412ILE A 411LEU A 296GLU A 410ARG A 401 | None | 1.13A | 2bxfB-5jk6A:undetectable | 2bxfB-5jk6A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jvb | PHOSPHONATE ABCTRANSPORTER,PERIPLASMICPHOSPHONATE-BINDINGPROTEIN (Trichodesmiumerythraeum) |
no annotation | 5 | LEU A 49ASN A 32PHE A 240GLU A 40LEU A 39 | None | 1.30A | 2bxfB-5jvbA:undetectable | 2bxfB-5jvbA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kbc | DSBA (Chlamydiatrachomatis) |
PF13462(Thioredoxin_4) | 5 | LEU A 155ASN A 158TYR A 98LEU A 66GLU A 35 | None | 1.10A | 2bxfB-5kbcA:undetectable | 2bxfB-5kbcA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l1t | PENTALENOLACTONESYNTHASE (Streptomycesarenae) |
PF00067(p450) | 5 | LEU A 247ILE A 272PHE A 365GLU A 271LEU A 329 | None | 1.30A | 2bxfB-5l1tA:undetectable | 2bxfB-5l1tA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2x | DNA-DIRECTEDPRIMASE/POLYMERASEPROTEIN (Homo sapiens) |
no annotation | 5 | LEU A 134ILE A 135CYH A 139TYR A 284CYH A 150 | None | 0.83A | 2bxfB-5l2xA:undetectable | 2bxfB-5l2xA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mtz | RIBONUCLEASE Z (Saccharomycescerevisiae) |
PF13691(Lactamase_B_4) | 5 | LEU A 718ILE A 756PHE A 692VAL A 489LEU A 507 | None | 1.15A | 2bxfB-5mtzA:undetectable | 2bxfB-5mtzA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nn7 | URACIL-DNAGLYCOSYLASE (Humangammaherpesvirus8) |
no annotation | 5 | LEU A 197ILE A 198LEU A 145VAL A 83LEU A 85 | None | 1.07A | 2bxfB-5nn7A:undetectable | 2bxfB-5nn7A:9.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 9 | ILE A 387ASN A 390PHE A 402TYR A 410LEU A 429VAL A 432GLU A 449LEU A 452ARG A 484 | None | 0.88A | 2bxfB-5oriA:49.4 | 2bxfB-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 7 | LEU A 386ILE A 387TYR A 410VAL A 432GLU A 449LEU A 452ARG A 484 | None | 1.14A | 2bxfB-5oriA:49.4 | 2bxfB-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uic | TWO-COMPONENTRESPONSE REGULATOR (Francisellatularensis) |
PF00072(Response_reg) | 5 | LEU A 105LEU A 29VAL A 27GLU A 18LEU A 17 | None | 1.30A | 2bxfB-5uicA:undetectable | 2bxfB-5uicA:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v9p | LYSINE-SPECIFICDEMETHYLASE 5A (Homo sapiens) |
PF00628(PHD)PF01388(ARID)PF02373(JmjC)PF02375(JmjN)PF02928(zf-C5HC2)PF08429(PLU-1) | 5 | ILE A 484LEU A 545VAL A 506GLU A 515LEU A 514 | None | 1.12A | 2bxfB-5v9pA:undetectable | 2bxfB-5v9pA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8p | HOMOSERINEO-ACETYLTRANSFERASE (Mycobacteroidesabscessus) |
PF00561(Abhydrolase_1) | 5 | LEU A 183VAL A 320CYH A 345GLU A 369LEU A 370 | None | 1.23A | 2bxfB-5w8pA:undetectable | 2bxfB-5w8pA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNIT (Komagataellaphaffii) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | LEU A1023TYR A 898VAL A 992CYH A 996ARG A1027 | None | 1.27A | 2bxfB-5xogA:2.4 | 2bxfB-5xogA:15.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xqw | FAB FRAGMENT OFCATALYTIC ANTIBODY7B9, LIGHT CHAIN (Mus musculus) |
no annotation | 5 | TYR L 86LEU L 104GLU L 79LEU L 78ARG L 61 | None | 1.27A | 2bxfB-5xqwL:undetectable | 2bxfB-5xqwL:9.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yax | SCFV1 ANTIBODY (Homo sapiens) |
no annotation | 5 | TYR A1102LEU A1124VAL A1126LEU A1094ARG A1075 | None | 1.18A | 2bxfB-5yaxA:undetectable | 2bxfB-5yaxA:14.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yo8 | TETRAPRENYL-BETA-CURCUMENE SYNTHASE (Bacillusalcalophilus) |
no annotation | 5 | ILE A 307VAL A 241GLU A 287LEU A 290ARG A 300 | None | 1.32A | 2bxfB-5yo8A:2.4 | 2bxfB-5yo8A:8.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 8 | ASN A 391PHE A 403TYR A 411LEU A 430VAL A 433GLU A 450LEU A 453ARG A 485 | None | 0.90A | 2bxfB-5yxeA:47.3 | 2bxfB-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 8 | LEU A 387ASN A 391PHE A 403TYR A 411VAL A 433GLU A 450LEU A 453ARG A 485 | None | 0.96A | 2bxfB-5yxeA:47.3 | 2bxfB-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bgz | LYSINE-SPECIFICDEMETHYLASE 5A,LINKED KDM5A JMJDOMAIN (Homo sapiens) |
no annotation | 5 | ILE A 484LEU A 545VAL A 506GLU A 515LEU A 514 | None | 1.26A | 2bxfB-6bgzA:undetectable | 2bxfB-6bgzA:7.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ek6 | LYSINE-SPECIFICDEMETHYLASE5B,LYSINE-SPECIFICDEMETHYLASE 5B (Homo sapiens) |
no annotation | 5 | ILE A 500LEU A 561VAL A 522GLU A 531LEU A 530 | DMS A 805 (-4.9A)NoneNoneDMS A 805 ( 4.6A)None | 1.30A | 2bxfB-6ek6A:undetectable | 2bxfB-6ek6A:7.86 |