SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXE_B_1FLB2003_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cbk | PROTEIN(7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE) (Haemophilusinfluenzae) |
PF01288(HPPK) | 5 | LEU A 94LEU A 19LEU A 23ILE A 26ALA A 7 | None | 1.15A | 2bxeB-1cbkA:undetectable | 2bxeB-1cbkA:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dvk | PRP18 (Saccharomycescerevisiae) |
PF02840(Prp18) | 5 | LEU A 147LEU A 121ARG A 235LEU A 236ALA A 142 | None | 0.97A | 2bxeB-1dvkA:undetectable | 2bxeB-1dvkA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dvk | PRP18 (Saccharomycescerevisiae) |
PF02840(Prp18) | 5 | LEU A 147LEU A 121LEU A 236ILE A 233ALA A 142 | None | 1.12A | 2bxeB-1dvkA:undetectable | 2bxeB-1dvkA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1faw | HEMOGLOBIN (ALPHASUBUNIT) (Anser anser) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ILE A 76ALA A 65 | NoneNoneHEM A 150 (-3.4A)NoneHEM A 150 ( 4.0A) | 1.00A | 2bxeB-1fawA:2.4 | 2bxeB-1fawA:13.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfu | LACCASE 1 (Coprinopsiscinerea) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | LEU A 385PHE A 331LEU A 400HIS A 403ILE A 464 | NoneNAG A 602 ( 4.5A)NoneNoneNone | 1.03A | 2bxeB-1hfuA:undetectable | 2bxeB-1hfuA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jjf | ENDO-1,4-BETA-XYLANASE Z (Ruminiclostridiumthermocellum) |
PF00756(Esterase) | 5 | LEU A 269LEU A 84LEU A 120ILE A 117ALA A 276 | None | 1.11A | 2bxeB-1jjfA:undetectable | 2bxeB-1jjfA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kj9 | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE 2 (Escherichiacoli) |
PF02222(ATP-grasp) | 5 | LEU A 308PHE A 307LEU A 34ARG A 33ALA A 301 | None | 1.06A | 2bxeB-1kj9A:undetectable | 2bxeB-1kj9A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kr4 | PROTEIN TM1056, CUTA (Thermotogamaritima) |
PF03091(CutA1) | 5 | LEU A 75HIS A 79LEU A 27ILE A 33ALA A 59 | None | 1.02A | 2bxeB-1kr4A:undetectable | 2bxeB-1kr4A:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o5j | PERIPLASMIC DIVALENTCATION TOLERANCEPROTEIN (Thermotogamaritima) |
PF03091(CutA1) | 5 | LEU A 69HIS A 73LEU A 21ILE A 27ALA A 53 | None | 0.96A | 2bxeB-1o5jA:undetectable | 2bxeB-1o5jA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r20 | ULTRASPIRACLEPROTEIN (Heliothisvirescens) |
PF00104(Hormone_recep) | 5 | LEU A 399LEU A 369ARG A 420LEU A 421ALA A 416 | None | 0.91A | 2bxeB-1r20A:undetectable | 2bxeB-1r20A:17.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 7 | TYR A 150LEU A 219ARG A 222PHE A 223HIS A 242ARG A 257ALA A 291 | DKA A1003 (-4.4A)NoneCIT A2001 ( 2.9A)NoneDKA A1003 (-3.7A)DKA A1003 (-4.1A)CIT A2001 ( 3.9A) | 0.82A | 2bxeB-1tf0A:47.7 | 2bxeB-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 9 | TYR A 150LEU A 219PHE A 223LEU A 238HIS A 242ARG A 257LEU A 260ILE A 264ALA A 291 | DKA A1003 (-4.4A)NoneNoneDKA A1003 (-4.3A)DKA A1003 (-3.7A)DKA A1003 (-4.1A)NoneNoneCIT A2001 ( 3.9A) | 0.34A | 2bxeB-1tf0A:47.7 | 2bxeB-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhf | PERIPLASMIC DIVALENTCATION TOLERANCEPROTEIN (Thermotogamaritima) |
PF03091(CutA1) | 5 | LEU A 69HIS A 73LEU A 21ILE A 27ALA A 53 | None | 0.95A | 2bxeB-1vhfA:undetectable | 2bxeB-1vhfA:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2amc | PHENYLALANYL-TRNASYNTHETASE ALPHACHAIN (Thermusthermophilus) |
PF01409(tRNA-synt_2d) | 5 | LEU A 244PHE A 245LEU A 110LEU A 317ALA A 323 | None | 1.06A | 2bxeB-2amcA:undetectable | 2bxeB-2amcA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3z | INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE (Sulfolobussolfataricus) |
PF00218(IGPS) | 5 | TYR A 69LEU A 33ARG A 36LEU A 231ALA A 77 | None | 1.12A | 2bxeB-2c3zA:undetectable | 2bxeB-2c3zA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dc0 | PROBABLE AMIDASE (Thermusthermophilus) |
PF01425(Amidase) | 5 | LEU A 3PHE A 218LEU A 70LEU A 104ILE A 222 | None | 0.99A | 2bxeB-2dc0A:undetectable | 2bxeB-2dc0A:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dh3 | 4F2 CELL-SURFACEANTIGEN HEAVY CHAIN (Homo sapiens) |
PF00128(Alpha-amylase) | 5 | LEU A 192PHE A 189LEU A 143LEU A 129ILE A 163 | None | 0.82A | 2bxeB-2dh3A:undetectable | 2bxeB-2dh3A:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2drw | D-AMINO ACID AMIDASE (Ochrobactrumanthropi) |
PF00144(Beta-lactamase) | 5 | LEU A 259PHE A 255LEU A 265LEU A 72ALA A 67 | None | 1.05A | 2bxeB-2drwA:undetectable | 2bxeB-2drwA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eia | EIAV CAPSID PROTEINP26 (Equineinfectiousanemia virus) |
PF00607(Gag_p24) | 5 | TYR A 129LEU A 32LEU A 57LEU A 71ALA A 136 | None | 1.08A | 2bxeB-2eiaA:undetectable | 2bxeB-2eiaA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fmy | CARBON MONOXIDEOXIDATION SYSTEMTRANSCRIPTIONREGULATOR COOA-1 (Carboxydothermushydrogenoformans) |
PF00027(cNMP_binding)PF13545(HTH_Crp_2) | 5 | LEU A 206ARG A 200LEU A 148LEU A 214ILE A 197 | None | 1.13A | 2bxeB-2fmyA:undetectable | 2bxeB-2fmyA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g37 | PROLINEDEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (Thermusthermophilus) |
PF01619(Pro_dh) | 5 | LEU A 150ARG A 117LEU A 146LEU A 100ALA A 114 | None | 1.15A | 2bxeB-2g37A:undetectable | 2bxeB-2g37A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j8x | URACIL-DNAGLYCOSYLASE (Humangammaherpesvirus4) |
PF03167(UDG) | 5 | TYR A 93PHE A 236LEU A 137LEU A 147ILE A 87 | None | 1.06A | 2bxeB-2j8xA:undetectable | 2bxeB-2j8xA:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jj7 | HEMOLYSIN IIREGULATORY PROTEIN (Bacillus cereus) |
PF00440(TetR_N) | 5 | LEU A 133PHE A 142LEU A 87ILE A 177ALA A 82 | None | 1.11A | 2bxeB-2jj7A:3.2 | 2bxeB-2jj7A:14.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjm | GLYCOSYLTRANSFERASE, GROUP 1FAMILY PROTEIN (Bacillusanthracis) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 5 | LEU A 335LEU A 201LEU A 276ILE A 299ALA A 328 | None | 0.98A | 2bxeB-2jjmA:undetectable | 2bxeB-2jjmA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kbb | TALIN-1 (Mus musculus) |
no annotation | 5 | LEU A1775LEU A1716LEU A1712ILE A1709ALA A1735 | None | 1.09A | 2bxeB-2kbbA:3.3 | 2bxeB-2kbbA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o6i | HD DOMAIN PROTEIN (Enterococcusfaecalis) |
PF01966(HD) | 5 | LEU A 204HIS A 21LEU A 208ILE A 211ALA A 182 | None | 1.05A | 2bxeB-2o6iA:undetectable | 2bxeB-2o6iA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oqa | LUFFACULIN 1 (Luffaacutangula) |
PF00161(RIP) | 5 | LEU A 238ARG A 162LEU A 25ILE A 18ALA A 158 | None | 1.12A | 2bxeB-2oqaA:undetectable | 2bxeB-2oqaA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pi5 | DNA-DIRECTED RNAPOLYMERASE (Escherichiavirus T7) |
PF00940(RNA_pol)PF14700(RPOL_N) | 5 | LEU A 512PHE A 509LEU A 497ILE A 341ALA A 336 | None | 1.14A | 2bxeB-2pi5A:3.8 | 2bxeB-2pi5A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pzi | PROBABLESERINE/THREONINE-PROTEIN KINASE PKNG (Mycobacteriumtuberculosis) |
PF00069(Pkinase)PF16918(PknG_TPR)PF16919(PknG_rubred) | 5 | LEU A 202ARG A 199PHE A 201LEU A 267ALA A 296 | None | 1.10A | 2bxeB-2pziA:undetectable | 2bxeB-2pziA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qps | ALPHA-AMYLASE TYPE AISOZYME (Hordeum vulgare) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 5 | TYR A 185LEU A 117LEU A 161HIS A 152LEU A 165 | None | 1.13A | 2bxeB-2qpsA:undetectable | 2bxeB-2qpsA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r80 | HEMOGLOBIN SUBUNITALPHA-A (Columba livia) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ILE A 76ALA A 65 | NoneNoneHEM A 150 (-3.3A)NoneHEM A 150 ( 4.0A) | 0.99A | 2bxeB-2r80A:2.3 | 2bxeB-2r80A:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vha | PERIPLASMIC BINDINGTRANSPORT PROTEIN (Shigellaflexneri) |
PF00497(SBP_bac_3) | 5 | LEU A 10PHE A 222LEU A 63ILE A 19ALA A 53 | None | 1.13A | 2bxeB-2vhaA:undetectable | 2bxeB-2vhaA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vvr | RIBOSE-5-PHOSPHATEISOMERASE B (Escherichiacoli) |
PF02502(LacAB_rpiB) | 5 | LEU A 105PHE A 107ARG A 26LEU A 23ILE A 19 | None | 0.96A | 2bxeB-2vvrA:undetectable | 2bxeB-2vvrA:14.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wdw | PUTATIVE HEXOSEOXIDASE (Nonomuraeagerenzanensis) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | TYR A 453PHE A 267LEU A 375LEU A 400ILE A 297 | None | 1.12A | 2bxeB-2wdwA:undetectable | 2bxeB-2wdwA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z63 | TOLL-LIKE RECEPTOR4, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF11921(DUF3439)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 83LEU A 85LEU A 66ILE A 48ALA A 97 | None | 1.09A | 2bxeB-2z63A:undetectable | 2bxeB-2z63A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z65 | TOLL-LIKE RECEPTOR4, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF11921(DUF3439)PF13306(LRR_5)PF13855(LRR_8) | 5 | LEU A 83LEU A 85LEU A 66ILE A 48ALA A 97 | None | 1.07A | 2bxeB-2z65A:undetectable | 2bxeB-2z65A:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3at6 | ALPHAA-GLOBIN (Podocnemisunifilis) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ILE A 76ALA A 65 | NoneNoneHEM A 142 (-3.3A)NoneHEM A 142 (-3.5A) | 1.08A | 2bxeB-3at6A:undetectable | 2bxeB-3at6A:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aw8 | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXYLASE, ATPASESUBUNIT (Thermusthermophilus) |
PF02222(ATP-grasp) | 5 | TYR A 65LEU A 245PHE A 256LEU A 237ALA A 94 | None | 1.14A | 2bxeB-3aw8A:undetectable | 2bxeB-3aw8A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b89 | 16S RRNA METHYLASE (Escherichiacoli) |
PF07091(FmrO) | 5 | LEU A 176LEU A 191LEU A 194ILE A 110ALA A 200 | None | 1.04A | 2bxeB-3b89A:3.0 | 2bxeB-3b89A:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dra | GERANYLGERANYLTRANSFERASE TYPE I BETASUBUNIT (Candidaalbicans) |
PF00432(Prenyltrans) | 5 | LEU B 367LEU B 4HIS B 9LEU B 326ALA B 353 | None | 1.09A | 2bxeB-3draB:undetectable | 2bxeB-3draB:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efv | PUTATIVESUCCINATE-SEMIALDEHYDE DEHYDROGENASE (Salmonellaenterica) |
PF00171(Aldedh) | 5 | ARG A 411LEU A 404LEU A 244ILE A 242ALA A 380 | None | 0.93A | 2bxeB-3efvA:undetectable | 2bxeB-3efvA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxi | TOLL-LIKE RECEPTOR 4 (Homo sapiens) |
PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 83LEU A 85LEU A 66ILE A 48ALA A 97 | None | 1.12A | 2bxeB-3fxiA:undetectable | 2bxeB-3fxiA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1w | MANNOSE-6-PHOSPHATEISOMERASE (Salmonellaenterica) |
PF01238(PMI_typeI) | 5 | LEU A 81PHE A 83LEU A 58LEU A 4ILE A 342 | None | 1.08A | 2bxeB-3h1wA:2.1 | 2bxeB-3h1wA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iuu | PUTATIVEMETALLOPEPTIDASE (Chelativoranssp. BNC1) |
PF07171(MlrC_C)PF07364(DUF1485) | 5 | LEU A 123ARG A 124LEU A 101LEU A 103ALA A 151 | None | 1.10A | 2bxeB-3iuuA:2.1 | 2bxeB-3iuuA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kdn | RIBULOSEBISPHOSPHATECARBOXYLASE (Thermococcuskodakarensis) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | TYR A 91LEU A 304LEU A 126LEU A 123ILE A 296 | None | 1.08A | 2bxeB-3kdnA:undetectable | 2bxeB-3kdnA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l2k | EHPF (Pantoeaagglomerans) |
PF00501(AMP-binding) | 5 | LEU A 198LEU A 216LEU A 213ILE A 233ALA A 138 | None | 1.09A | 2bxeB-3l2kA:undetectable | 2bxeB-3l2kA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m9v | FAD-DEPENDENTOXIDOREDUCTASE (Actinomadurakijaniata) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | LEU A 57LEU A 29LEU A 33ILE A 36ALA A 97 | None | 1.04A | 2bxeB-3m9vA:undetectable | 2bxeB-3m9vA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o9p | PERIPLASMIC MUREINPEPTIDE-BINDINGPROTEIN (Escherichiacoli) |
PF00496(SBP_bac_5) | 5 | LEU A 158PHE A 164LEU A 152LEU A 148ILE A 118 | None | 0.98A | 2bxeB-3o9pA:2.1 | 2bxeB-3o9pA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q8x | ZETA-TOXIN (Streptococcuspyogenes) |
PF06414(Zeta_toxin) | 5 | PHE B 69LEU B 20LEU B 106ILE B 64ALA B 101 | None | 1.14A | 2bxeB-3q8xB:2.3 | 2bxeB-3q8xB:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rpw | ABC TRANSPORTER (Rhodopseudomonaspalustris) |
PF13416(SBP_bac_8) | 5 | LEU A 118LEU A 285LEU A 281ILE A 105ALA A 132 | None | 1.11A | 2bxeB-3rpwA:undetectable | 2bxeB-3rpwA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t66 | NICKEL ABCTRANSPORTER(NICKEL-BINDINGPROTEIN) (Bacillushalodurans) |
PF00496(SBP_bac_5) | 5 | LEU A 381PHE A 350LEU A 330ILE A 359ALA A 261 | None | 1.06A | 2bxeB-3t66A:undetectable | 2bxeB-3t66A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6q | CD180 ANTIGEN (Mus musculus) |
PF13855(LRR_8) | 5 | LEU A 113LEU A 108LEU A 130ILE A 143ALA A 120 | None | 1.14A | 2bxeB-3t6qA:undetectable | 2bxeB-3t6qA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3teh | PHENYLALANYL-TRNASYNTHETASE ALPHACHAIN (Thermusthermophilus) |
PF01409(tRNA-synt_2d) | 5 | LEU A 244PHE A 245LEU A 110LEU A 317ALA A 323 | None | 1.09A | 2bxeB-3tehA:undetectable | 2bxeB-3tehA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr7 | URACIL-DNAGLYCOSYLASE (Coxiellaburnetii) |
PF03167(UDG) | 5 | TYR A 69PHE A 205LEU A 113LEU A 123ILE A 63 | None | 1.10A | 2bxeB-3tr7A:undetectable | 2bxeB-3tr7A:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u44 | ATP-DEPENDENTHELICASE/NUCLEASESUBUNIT A (Bacillussubtilis) |
PF00580(UvrD-helicase)PF12705(PDDEXK_1)PF13361(UvrD_C) | 6 | TYR A 718LEU A 758LEU A 630LEU A 627ILE A 765ALA A 747 | None | 1.38A | 2bxeB-3u44A:undetectable | 2bxeB-3u44A:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3umc | HALOACIDDEHALOGENASE (Pseudomonasaeruginosa) |
PF13419(HAD_2) | 5 | LEU A 34PHE A 23LEU A 81LEU A 83ILE A 91 | None | 1.15A | 2bxeB-3umcA:undetectable | 2bxeB-3umcA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3umc | HALOACIDDEHALOGENASE (Pseudomonasaeruginosa) |
PF13419(HAD_2) | 5 | LEU A 34PHE A 23LEU A 87ILE A 91ALA A 76 | None | 1.04A | 2bxeB-3umcA:undetectable | 2bxeB-3umcA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w4u | HEMOGLOBIN SUBUNITZETA (Homo sapiens) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ILE A 76ALA A 65 | NoneNoneHEM A 201 ( 3.2A)NoneHEM A 201 ( 3.7A) | 1.06A | 2bxeB-3w4uA:2.1 | 2bxeB-3w4uA:13.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wtg | HEMOGLOBIN SUBUNITALPHA-A (Dromaiusnovaehollandiae) |
PF00042(Globin) | 5 | PHE A 128LEU A 136HIS A 87ILE A 76ALA A 65 | NoneNoneHEM A 201 ( 3.2A)NoneHEM A 201 ( 3.8A) | 0.97A | 2bxeB-3wtgA:2.1 | 2bxeB-3wtgA:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akk | NITRATE REGULATORYPROTEIN (Klebsiellaoxytoca) |
PF03861(ANTAR)PF08376(NIT) | 5 | LEU A 86PHE A 82LEU A 97ILE A 142ALA A 102 | None | 1.01A | 2bxeB-4akkA:undetectable | 2bxeB-4akkA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9d | SERINE/THREONINE-PROTEIN KINASE NEK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 116HIS A 120LEU A 144ILE A 134ALA A 188 | None CL A1287 (-4.1A)NoneNoneNone | 1.10A | 2bxeB-4b9dA:undetectable | 2bxeB-4b9dA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bju | N-ACETYLGLUCOSAMINE-PHOSPHATE MUTASE (Aspergillusfumigatus) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I) | 5 | PHE A 389HIS A 441LEU A 434ILE A 421ALA A 416 | None | 0.93A | 2bxeB-4bjuA:undetectable | 2bxeB-4bjuA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ern | TFIIH BASALTRANSCRIPTION FACTORCOMPLEX HELICASE XPBSUBUNIT (Homo sapiens) |
PF16203(ERCC3_RAD25_C) | 5 | LEU A 662LEU A 547HIS A 551LEU A 693ALA A 508 | None | 0.97A | 2bxeB-4ernA:undetectable | 2bxeB-4ernA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l5n | URACIL-DNAGLYCOSYLASE (Humanalphaherpesvirus1) |
PF03167(UDG) | 5 | TYR A 90PHE A 225LEU A 135LEU A 145ILE A 84 | None | 1.06A | 2bxeB-4l5nA:undetectable | 2bxeB-4l5nA:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lhs | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF14606(Lipase_GDSL_3)PF14607(GxDLY) | 5 | LEU A 157PHE A 50LEU A 109LEU A 149ILE A 77 | None | 1.00A | 2bxeB-4lhsA:undetectable | 2bxeB-4lhsA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lu1 | MAF-LIKE PROTEINYCEF (Escherichiacoli) |
PF02545(Maf) | 5 | LEU A 6ARG A 14PHE A 24LEU A 177ALA A 15 | None | 1.01A | 2bxeB-4lu1A:2.0 | 2bxeB-4lu1A:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbg | CAAXFARNESYLTRANSFERASEBETA SUBUNIT RAM1 (Aspergillusfumigatus) |
PF00432(Prenyltrans) | 5 | LEU B 491LEU B 124HIS B 129LEU B 411ALA B 437 | None | 0.94A | 2bxeB-4mbgB:undetectable | 2bxeB-4mbgB:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n3s | EUKARYOTICTRANSLATIONINITIATION FACTOR 5B (Saccharomycescerevisiae) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF11987(IF-2) | 5 | LEU A 472PHE A 447LEU A 612LEU A 608ILE A 425 | None | 1.13A | 2bxeB-4n3sA:undetectable | 2bxeB-4n3sA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nmn | REPLICATIVE DNAHELICASE (Aquifexaeolicus) |
PF00772(DnaB)PF03796(DnaB_C) | 5 | LEU A 217LEU A 243LEU A 286ILE A 284ALA A 314 | None | 1.09A | 2bxeB-4nmnA:undetectable | 2bxeB-4nmnA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oun | MINI-RIBONUCLEASE 3 (Bacillussubtilis) |
PF00636(Ribonuclease_3) | 5 | LEU A 129PHE A 46LEU A 85ILE A 81ALA A 146 | None | 0.93A | 2bxeB-4ounA:2.6 | 2bxeB-4ounA:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p72 | PHENYLALANINE--TRNALIGASE BETA SUBUNIT (Pseudomonasaeruginosa) |
PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 5 | LEU A 735ARG A 785LEU A 782ILE A 778ALA A 726 | None | 0.85A | 2bxeB-4p72A:undetectable | 2bxeB-4p72A:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj6 | LEUCYL-CYSTINYLAMINOPEPTIDASE (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | LEU A1025PHE A 750LEU A 787LEU A 779ILE A 775 | None | 0.95A | 2bxeB-4pj6A:undetectable | 2bxeB-4pj6A:21.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | LEU A 219PHE A 223LEU A 238HIS A 242LEU A 260ILE A 290 | None | 1.48A | 2bxeB-4po0A:48.1 | 2bxeB-4po0A:74.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | TYR A 150ARG A 222LEU A 238HIS A 242ARG A 257LEU A 260 | None | 0.80A | 2bxeB-4po0A:48.1 | 2bxeB-4po0A:74.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 7 | TYR A 150LEU A 219PHE A 223LEU A 238HIS A 242ARG A 257LEU A 260 | None | 0.52A | 2bxeB-4po0A:48.1 | 2bxeB-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3p | 4-ALPHA-GLUCANOTRANSFERASE (Escherichiacoli) |
PF02446(Glyco_hydro_77) | 5 | LEU A 375HIS A 188ARG A 373LEU A 445ALA A 437 | None | 1.14A | 2bxeB-4s3pA:undetectable | 2bxeB-4s3pA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx8 | PROBABLE CHITINASE A (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 5 | LEU A 228PHE A 226LEU A 193LEU A 157ALA A 214 | None | 0.96A | 2bxeB-4tx8A:undetectable | 2bxeB-4tx8A:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u0z | ADENOSINEMONOPHOSPHATE-PROTEIN TRANSFERASE FICD (Homo sapiens) |
PF02661(Fic) | 5 | LEU A 426HIS A 347LEU A 381ILE A 389ALA A 419 | None | 1.11A | 2bxeB-4u0zA:undetectable | 2bxeB-4u0zA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zdn | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A 741LEU A 748HIS A 669LEU A 798ALA A 805 | None | 1.13A | 2bxeB-4zdnA:undetectable | 2bxeB-4zdnA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5t | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT A (Oryctolaguscuniculus) |
PF01399(PCI) | 5 | LEU A 455PHE A 452LEU A 440ILE A 484ALA A 470 | None | 1.14A | 2bxeB-5a5tA:2.1 | 2bxeB-5a5tA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5t | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT CEUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT E (Oryctolaguscuniculus) |
PF01399(PCI)PF05470(eIF-3c_N)PF09440(eIF3_N) | 5 | LEU C 594HIS E 12LEU C 588ILE C 573ALA C 568 | None | 1.12A | 2bxeB-5a5tC:2.6 | 2bxeB-5a5tC:20.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 9 | TYR A 149LEU A 218PHE A 222LEU A 237HIS A 241ARG A 256LEU A 259ILE A 263ALA A 290 | PG4 A 602 (-4.9A)NoneNonePG4 A 602 (-4.7A)PG4 A 602 (-4.0A)PG4 A 602 (-4.1A)PG4 A 602 ( 4.5A)NonePG4 A 602 (-3.4A) | 0.43A | 2bxeB-5dqfA:48.1 | 2bxeB-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5o | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | LEU A 59PHE A 132LEU A 52ILE A 185ALA A 41 | None | 1.10A | 2bxeB-5f5oA:undetectable | 2bxeB-5f5oA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fmf | DNA REPAIR HELICASERAD25, SSL2 (Saccharomycescerevisiae) |
PF04851(ResIII)PF16203(ERCC3_RAD25_C) | 5 | LEU 1 708LEU 1 594HIS 1 598LEU 1 739ALA 1 555 | None | 0.97A | 2bxeB-5fmf1:undetectable | 2bxeB-5fmf1:21.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 7 | TYR A 150ARG A 222LEU A 238HIS A 242ARG A 257LEU A 260ALA A 291 | None | 0.73A | 2bxeB-5ghkA:46.3 | 2bxeB-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 8 | TYR A 150LEU A 219PHE A 223LEU A 238HIS A 242ARG A 257LEU A 260ALA A 291 | None | 0.42A | 2bxeB-5ghkA:46.3 | 2bxeB-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h9f | CRISPR SYSTEMCASCADE SUBUNIT CASB (Escherichiacoli) |
PF09485(CRISPR_Cse2) | 5 | LEU B 117LEU B 87LEU B 128ILE B 72ALA B 124 | None | 1.06A | 2bxeB-5h9fB:1.9 | 2bxeB-5h9fB:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jgg | ALPHA CHAIN (Acipenserpersicus) |
PF00042(Globin) | 5 | PHE A 129LEU A 137HIS A 88ILE A 77ALA A 66 | NoneNoneHEM A 201 (-3.3A)NoneHEM A 201 ( 3.7A) | 1.05A | 2bxeB-5jggA:2.2 | 2bxeB-5jggA:12.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jnz | ALPHA CHAIN (Acipenserstellatus) |
PF00042(Globin) | 5 | PHE A 129LEU A 137HIS A 88ILE A 77ALA A 66 | NoneNoneHEM A 201 (-3.4A)NoneHEM A 201 ( 3.8A) | 1.04A | 2bxeB-5jnzA:2.0 | 2bxeB-5jnzA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kei | 2,3-DIHYDROXYBENZOATE-AMP LIGASE (Mycolicibacteriumsmegmatis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | LEU A 112PHE A 108LEU A 209ARG A 225ALA A 262 | None | 1.12A | 2bxeB-5keiA:undetectable | 2bxeB-5keiA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l1t | PENTALENOLACTONESYNTHASE (Streptomycesarenae) |
PF00067(p450) | 5 | LEU A 249LEU A 371LEU A 136ILE A 394ALA A 374 | None | 1.14A | 2bxeB-5l1tA:2.4 | 2bxeB-5l1tA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m42 | PROLINEDEHYDROGENASE (Thermusthermophilus) |
PF01619(Pro_dh) | 5 | LEU A 150ARG A 117LEU A 146LEU A 100ALA A 114 | None | 1.13A | 2bxeB-5m42A:undetectable | 2bxeB-5m42A:19.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | LEU A 218ARG A 217ARG A 256LEU A 259ILE A 263ALA A 290 | None | 1.09A | 2bxeB-5oriA:47.9 | 2bxeB-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 9 | TYR A 149LEU A 218PHE A 222LEU A 237HIS A 241ARG A 256LEU A 259ILE A 263ALA A 290 | None | 0.59A | 2bxeB-5oriA:47.9 | 2bxeB-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w6l | RTXREPEAT-CONTAININGCYTOTOXIN (Vibriovulnificus) |
no annotation | 5 | LEU A3598LEU A3620HIS A3624LEU A3638ILE A3642 | LEU A3598 ( 0.6A)LEU A3620 ( 0.6A)HIS A3624 ( 1.0A)LEU A3638 ( 0.6A)ILE A3642 ( 0.7A) | 1.08A | 2bxeB-5w6lA:3.7 | 2bxeB-5w6lA:9.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsq | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | LEU A 43PHE A 116LEU A 36ILE A 169ALA A 25 | None | 1.02A | 2bxeB-5xsqA:2.4 | 2bxeB-5xsqA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 8 | TYR A 150LEU A 219PHE A 223LEU A 238HIS A 242ARG A 257LEU A 260ILE A 264 | None | 0.64A | 2bxeB-5yxeA:46.3 | 2bxeB-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yzc | GLYCOPROTEINF1,MEASLES VIRUSFUSION PROTEINGLYCOPROTEIN F2 (Measlesmorbillivirus) |
no annotation | 5 | LEU B 216PHE B 217LEU B 238ILE A 56ALA B 267 | None | 1.10A | 2bxeB-5yzcB:undetectable | 2bxeB-5yzcB:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvs | PUTATIVE COREPROTEIN NTPASE/VP5 (Aquareovirus C) |
no annotation | 5 | LEU 4 27PHE 4 37LEU 4 209ILE 4 4ALA 4 243 | None | 0.91A | 2bxeB-5zvs4:undetectable | 2bxeB-5zvs4:8.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ez8 | HUNTINGTIN (Homo sapiens) |
no annotation | 5 | LEU A2253LEU A2303LEU A2395ILE A2391ALA A2281 | None | 1.12A | 2bxeB-6ez8A:undetectable | 2bxeB-6ez8A:6.81 |