SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXE_A_1FLA2002_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hbr | PROTEIN (HEMOGLOBIND) (Gallus gallus) |
PF00042(Globin) | 5 | ALA A 69LEU A 76SER A 84LEU A 136VAL A 135 | None | 1.11A | 2bxeA-1hbrA:2.1 | 2bxeA-1hbrA:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hds | HEMOGLOBIN S (DEOXY)(ALPHA CHAIN) (Odocoileusvirginianus) |
PF00042(Globin) | 5 | ALA A 69LEU A 76SER A 84LEU A 136VAL A 135 | None | 1.08A | 2bxeA-1hdsA:undetectable | 2bxeA-1hdsA:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kij | DNA GYRASE SUBUNIT B (Thermusthermophilus) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 5 | ALA A 348ALA A 345LEU A 340LEU A 327ALA A 270 | None | 1.02A | 2bxeA-1kijA:undetectable | 2bxeA-1kijA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1li7 | CYSTEINYL-TRNASYNTHETASE (Escherichiacoli) |
PF01406(tRNA-synt_1e)PF09190(DALR_2) | 5 | PHE A 350ALA A 355LEU A 359LEU A 391VAL A 49 | None | 1.09A | 2bxeA-1li7A:undetectable | 2bxeA-1li7A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogq | POLYGALACTURONASEINHIBITING PROTEIN (Phaseolusvulgaris) |
PF08263(LRRNT_2) | 5 | PHE A 293ALA A 297ALA A 229SER A 272LEU A 273 | NoneNAG A1317 ( 4.0A)NoneNoneNone | 1.07A | 2bxeA-1ogqA:undetectable | 2bxeA-1ogqA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s0h | HEMOGLOBIN ALPHACHAIN (Equus asinus) |
PF00042(Globin) | 5 | ALA A 69LEU A 76SER A 84LEU A 136VAL A 135 | None | 1.14A | 2bxeA-1s0hA:undetectable | 2bxeA-1s0hA:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szi | MANNOSE-6-PHOSPHATERECEPTOR BINDINGPROTEIN 1 (Mus musculus) |
PF03036(Perilipin) | 5 | ALA A 265ALA A 269LEU A 273LEU A 405ALA A 401 | None | 1.12A | 2bxeA-1sziA:2.4 | 2bxeA-1sziA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szi | MANNOSE-6-PHOSPHATERECEPTOR BINDINGPROTEIN 1 (Mus musculus) |
PF03036(Perilipin) | 5 | ALA A 265ALA A 269LEU A 273LEU A 405LEU A 262 | None | 1.24A | 2bxeA-1sziA:2.4 | 2bxeA-1sziA:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t8q | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE,PERIPLASMIC (Escherichiacoli) |
PF03009(GDPD) | 5 | ALA A 52ALA A 54LEU A 62LEU A 158VAL A 155 | None | 1.20A | 2bxeA-1t8qA:undetectable | 2bxeA-1t8qA:21.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 10 | PHE A 206ALA A 210ALA A 213LEU A 331LEU A 347ALA A 350GLU A 354SER A 480LEU A 481VAL A 482 | NoneDKA A1002 (-3.3A)DKA A1001 ( 4.0A)NoneDKA A1002 ( 4.3A)DKA A1002 ( 3.8A)DKA A1002 ( 4.4A)DKA A1002 (-3.4A)NoneDKA A1002 (-4.2A) | 0.46A | 2bxeA-1tf0A:47.5 | 2bxeA-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urj | MAJOR DNA-BINDINGPROTEIN (Humanalphaherpesvirus1) |
PF00747(Viral_DNA_bp) | 5 | ALA A 319ALA A 323LEU A 678LEU A 252ALA A 251 | None | 1.19A | 2bxeA-1urjA:0.0 | 2bxeA-1urjA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9s | URACILPHOSPHORIBOSYLTRANSFERASE (Thermusthermophilus) |
PF14681(UPRTase) | 5 | ALA A 142ALA A 139LEU A 133LEU A 156LEU A 146 | NoneSO4 A 517 (-4.1A)NoneNoneNone | 1.22A | 2bxeA-1v9sA:undetectable | 2bxeA-1v9sA:16.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve5 | THREONINE DEAMINASE (Thermusthermophilus) |
PF00291(PALP) | 5 | ALA A 55ALA A 59LEU A 62LEU A 68ALA A 138 | None | 1.02A | 2bxeA-1ve5A:undetectable | 2bxeA-1ve5A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlv | ORNITHINECARBAMOYLTRANSFERASE (Thermotogamaritima) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | ALA A 95LEU A 91LEU A 118SER A 9VAL A 126 | None | 1.17A | 2bxeA-1vlvA:undetectable | 2bxeA-1vlvA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z6t | APOPTOTIC PROTEASEACTIVATING FACTOR 1 (Homo sapiens) |
PF00619(CARD)PF00931(NB-ARC) | 5 | ALA A 164ALA A 167LEU A 173LEU A 140VAL A 150 | None | 1.16A | 2bxeA-1z6tA:undetectable | 2bxeA-1z6tA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akj | FERREDOXIN--NITRITEREDUCTASE,CHLOROPLAST (Spinaciaoleracea) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | ALA A 278LEU A 335GLU A 320LEU A 260VAL A 261 | None | 1.18A | 2bxeA-2akjA:2.0 | 2bxeA-2akjA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b25 | HYPOTHETICAL PROTEIN (Homo sapiens) |
PF08704(GCD14) | 5 | PHE A 186LEU A 96LEU A 121ALA A 124VAL A 131 | None | 0.75A | 2bxeA-2b25A:undetectable | 2bxeA-2b25A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fe1 | CONSERVEDHYPOTHETICAL PROTEINPAE0151 (Pyrobaculumaerophilum) |
PF01850(PIN) | 5 | ALA A 26ALA A 30LEU A 33LEU A 115VAL A 5 | None | 1.13A | 2bxeA-2fe1A:undetectable | 2bxeA-2fe1A:14.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fr1 | ERYTHROMYCINSYNTHASE, ERYAI (Saccharopolysporaerythraea) |
PF08659(KR) | 5 | ALA A1542LEU A1549ALA A1591LEU A1778VAL A1777 | None | 1.06A | 2bxeA-2fr1A:undetectable | 2bxeA-2fr1A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g5t | DIPEPTIDYL PEPTIDASE4 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | ALA A 576LEU A 544LEU A 542ALA A 610VAL A 619 | None | 1.15A | 2bxeA-2g5tA:undetectable | 2bxeA-2g5tA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jfn | GLUTAMATE RACEMASE (Escherichiacoli) |
PF01177(Asp_Glu_race) | 5 | LEU A 168LEU A 183ALA A 182LEU A 218VAL A 217 | None | 1.16A | 2bxeA-2jfnA:undetectable | 2bxeA-2jfnA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pxx | UNCHARACTERIZEDPROTEIN MGC2408 (Homo sapiens) |
PF08241(Methyltransf_11) | 5 | PHE A 124LEU A 52LEU A 128LEU A 63VAL A 64 | None | 1.19A | 2bxeA-2pxxA:undetectable | 2bxeA-2pxxA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ra1 | SURFACE LAYERPROTEIN (Geobacillusstearothermophilus) |
PF13205(Big_5) | 5 | ALA A 211ALA A 223LEU A 220ALA A 259GLU A 257 | None | 1.11A | 2bxeA-2ra1A:3.4 | 2bxeA-2ra1A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v3c | SIGNAL RECOGNITION54 KDA PROTEIN (Methanocaldococcusjannaschii) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 5 | LEU C 5LEU C 38ALA C 37LEU C 47VAL C 48 | None | 1.17A | 2bxeA-2v3cC:3.9 | 2bxeA-2v3cC:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vw9 | SINGLE-STRANDED DNABINDING PROTEIN (Helicobacterpylori) |
PF00436(SSB) | 5 | ALA A1099LEU A1055ALA A1063LEU A1074VAL A1073 | None | 1.06A | 2bxeA-2vw9A:undetectable | 2bxeA-2vw9A:11.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4d | ACYLPHOSPHATASE (Pyrococcushorikoshii) |
PF00708(Acylphosphatase) | 5 | ALA A 46LEU A 8LEU A 48ALA A 6VAL A 32 | None | 1.24A | 2bxeA-2w4dA:undetectable | 2bxeA-2w4dA:10.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xua | 3-OXOADIPATEENOL-LACTONASE (Paraburkholderiaxenovorans) |
PF12146(Hydrolase_4) | 5 | ALA A 192ALA A 196LEU A 198LEU A 104ALA A 108 | None | 1.07A | 2bxeA-2xuaA:undetectable | 2bxeA-2xuaA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yva | DNAAINITIATOR-ASSOCIATING PROTEIN DIAA (Escherichiacoli) |
PF13580(SIS_2) | 5 | ALA A 115LEU A 182ALA A 30LEU A 113VAL A 112 | None | 1.17A | 2bxeA-2yvaA:undetectable | 2bxeA-2yvaA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywg | GTP-BINDING PROTEINLEPA (Aquifexaeolicus) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF06421(LepA_C) | 5 | PHE A 118LEU A 439GLU A 447LEU A 153VAL A 152 | None | 1.23A | 2bxeA-2ywgA:undetectable | 2bxeA-2ywgA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxg | DIHYDRODIPICOLINATESYNTHASE (Methanocaldococcusjannaschii) |
PF00701(DHDPS) | 5 | ALA A 253LEU A 279ALA A 240SER A 202VAL A 204 | None | 1.14A | 2bxeA-2yxgA:undetectable | 2bxeA-2yxgA:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ady | DOTD (Legionellapneumophila) |
PF16816(DotD) | 5 | ALA A 99ALA A 101LEU A 41LEU A 128ALA A 83 | None | 1.03A | 2bxeA-3adyA:undetectable | 2bxeA-3adyA:12.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiv | BETA-GLUCOSIDASE (Secale cereale) |
PF00232(Glyco_hydro_1) | 5 | LEU A 322LEU A 236ALA A 239GLU A 243VAL A 165 | None | 0.99A | 2bxeA-3aivA:undetectable | 2bxeA-3aivA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3azq | AMINOPEPTIDASE (Streptomycesmorookaense) |
PF00326(Peptidase_S9) | 5 | ALA A 639LEU A 658LEU A 586ALA A 616LEU A 533 | None | 0.93A | 2bxeA-3azqA:undetectable | 2bxeA-3azqA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b0h | NITRITE REDUCTASE (Nicotianatabacum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | ALA A 278LEU A 335GLU A 320LEU A 260VAL A 261 | None | 1.10A | 2bxeA-3b0hA:undetectable | 2bxeA-3b0hA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c7j | TRANSCRIPTIONALREGULATOR, GNTRFAMILY (Pseudomonassyringae groupgenomosp. 3) |
PF00392(GntR)PF07729(FCD) | 5 | ALA A 122ALA A 124LEU A 151LEU A 196ALA A 199 | None | 1.09A | 2bxeA-3c7jA:undetectable | 2bxeA-3c7jA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm5 | SIGNAL RECOGNITION54 KDA PROTEIN (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 5 | LEU A 6LEU A 39ALA A 38LEU A 48VAL A 49 | None | 1.25A | 2bxeA-3dm5A:3.8 | 2bxeA-3dm5A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm5 | SIGNAL RECOGNITION54 KDA PROTEIN (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 5 | LEU A 10LEU A 39ALA A 38LEU A 48VAL A 49 | None | 1.18A | 2bxeA-3dm5A:3.8 | 2bxeA-3dm5A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fse | TWO-DOMAIN PROTEINCONTAININGDJ-1/THIJ/PFPI-LIKEAND FERRITIN-LIKEDOMAINS (Trichormusvariabilis) |
PF01965(DJ-1_PfpI)PF09537(DUF2383) | 5 | PHE A 73LEU A 173LEU A 32ALA A 35VAL A 39 | None | 0.66A | 2bxeA-3fseA:2.9 | 2bxeA-3fseA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fut | DIMETHYLADENOSINETRANSFERASE (Thermusthermophilus) |
PF00398(RrnaAD) | 5 | PHE A 51ALA A 43LEU A 64ALA A 67VAL A 71 | None | 1.16A | 2bxeA-3futA:undetectable | 2bxeA-3futA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gor | PUTATIVEMETAL-DEPENDENTHYDROLASE (Geobacillusstearothermophilus) |
PF05163(DinB) | 5 | ALA A 41ALA A 45LEU A 49LEU A 78ALA A 82 | None | 1.17A | 2bxeA-3gorA:2.3 | 2bxeA-3gorA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gqp | HEMOGLOBIN SUBUNITALPHA (Felis catus) |
PF00042(Globin) | 5 | ALA A 69LEU A 76SER A 84LEU A 136VAL A 135 | NoneNoneNoneHEM A 143 (-4.9A)None | 0.99A | 2bxeA-3gqpA:undetectable | 2bxeA-3gqpA:14.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4x | PHOSPHATIDYLINOSITOL-SPECIFICPHOSPHOLIPASE C1 (Streptomycesantibioticus) |
PF16670(PI-PLC-C1) | 5 | ALA A 315LEU A 312LEU A 267ALA A 263SER A 270 | None | 1.04A | 2bxeA-3h4xA:undetectable | 2bxeA-3h4xA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h75 | PERIPLASMICSUGAR-BINDING DOMAINPROTEIN (Pseudomonasprotegens) |
PF13407(Peripla_BP_4) | 5 | ALA A 253ALA A 256LEU A 236SER A 292LEU A 291 | None | 1.16A | 2bxeA-3h75A:undetectable | 2bxeA-3h75A:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hl6 | PATHOGENICITY ISLANDPROTEIN (Staphylococcusaureus) |
PF16560(SAPI) | 5 | LEU A 79LEU A 53ALA A 71SER A 28LEU A 24 | None | 1.17A | 2bxeA-3hl6A:undetectable | 2bxeA-3hl6A:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 5 | ALA A 924LEU A 926LEU A 908LEU A 916VAL A 913 | None | 1.20A | 2bxeA-3hmjA:undetectable | 2bxeA-3hmjA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihv | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | LEU A 260ALA A 420GLU A 480SER A 346LEU A 345 | None | 1.15A | 2bxeA-3ihvA:undetectable | 2bxeA-3ihvA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kdn | RIBULOSEBISPHOSPHATECARBOXYLASE (Thermococcuskodakarensis) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | ALA A 109LEU A 123ALA A 27LEU A 301VAL A 300 | None | 1.17A | 2bxeA-3kdnA:undetectable | 2bxeA-3kdnA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3knz | PUTATIVE SUGARBINDING PROTEIN (Salmonellaenterica) |
PF01380(SIS) | 5 | ALA A 25ALA A 22LEU A 153LEU A 81VAL A 31 | None | 1.25A | 2bxeA-3knzA:undetectable | 2bxeA-3knzA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvt | 3-DEOXY-D-ARABINO-HEPTULOSONATE7-PHOSPHATE SYNTHASE (Listeriamonocytogenes) |
PF00793(DAHP_synth_1)PF01817(CM_2) | 5 | ALA A 209LEU A 218ALA A 244SER A 235LEU A 234 | None | 1.25A | 2bxeA-3nvtA:3.3 | 2bxeA-3nvtA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ot4 | PUTATIVEISOCHORISMATASE (Bordetellabronchiseptica) |
PF00857(Isochorismatase) | 5 | ALA A 16ALA A 193LEU A 166LEU A 19GLU A 199 | None | 1.24A | 2bxeA-3ot4A:undetectable | 2bxeA-3ot4A:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p39 | NONSTRUCTURALPROTEIN 1 (Influenza Avirus) |
PF00600(Flu_NS1) | 5 | ALA A 172LEU A 125LEU A 142ALA A 144LEU A 110 | None | 1.19A | 2bxeA-3p39A:undetectable | 2bxeA-3p39A:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pb9 | GLUTAMINYL-PEPTIDECYCLOTRANSFERASE-LIKE PROTEIN (Homo sapiens) |
PF04389(Peptidase_M28) | 5 | ALA X 373LEU X 88LEU X 197ALA X 200GLU X 204 | None | 1.17A | 2bxeA-3pb9X:undetectable | 2bxeA-3pb9X:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pft | FLAVIN REDUCTASE (Mycolicibacteriumgoodii) |
PF01613(Flavin_Reduct) | 5 | ALA A 26ALA A 24LEU A 76LEU A 87ALA A 83 | None | 1.18A | 2bxeA-3pftA:undetectable | 2bxeA-3pftA:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q10 | PANTOATE--BETA-ALANINE LIGASE (Yersinia pestis) |
PF02569(Pantoate_ligase) | 5 | ALA A 201LEU A 193LEU A 269ALA A 272LEU A 233 | None | 1.24A | 2bxeA-3q10A:undetectable | 2bxeA-3q10A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7a | PHOSPHOGLYCERATEMUTASE, PUTATIVE (Bacillusanthracis) |
PF00300(His_Phos_1) | 5 | ALA A 68ALA A 72LEU A 76LEU A 86ALA A 60 | None | 1.00A | 2bxeA-3r7aA:undetectable | 2bxeA-3r7aA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rfb | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcuspneumoniae) |
PF13185(GAF_2) | 5 | ALA A 34LEU A 127LEU A 125LEU A 150VAL A 147 | None | 1.17A | 2bxeA-3rfbA:undetectable | 2bxeA-3rfbA:14.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sfz | APOPTOTIC PEPTIDASEACTIVATING FACTOR 1 (Mus musculus) |
PF00400(WD40)PF00931(NB-ARC)PF12894(ANAPC4_WD40) | 5 | ALA A 164ALA A 167LEU A 173LEU A 140VAL A 150 | None | 1.17A | 2bxeA-3sfzA:undetectable | 2bxeA-3sfzA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqz | PUTATIVEHYDROXYMETHYLGLUTARYL-COA SYNTHASE (Streptococcusmutans) |
PF00195(Chal_sti_synt_N)PF08540(HMG_CoA_synt_C) | 5 | ALA A 55ALA A 59LEU A 63LEU A 134LEU A 76 | None | 1.23A | 2bxeA-3sqzA:undetectable | 2bxeA-3sqzA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3un9 | NLR FAMILY MEMBER X1 (Homo sapiens) |
PF13516(LRR_6) | 5 | ALA A 847LEU A 883LEU A 870ALA A 856VAL A 842 | None | 1.25A | 2bxeA-3un9A:2.8 | 2bxeA-3un9A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uw2 | PHOSPHOGLUCOMUTASE/PHOSPHOMANNOMUTASEFAMILY PROTEIN (Burkholderiathailandensis) |
PF00408(PGM_PMM_IV)PF02878(PGM_PMM_I)PF02879(PGM_PMM_II)PF02880(PGM_PMM_III) | 5 | ALA A 279ALA A 321LEU A 316LEU A 273VAL A 272 | None | 1.24A | 2bxeA-3uw2A:undetectable | 2bxeA-3uw2A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v7i | PUTATIVE POLYKETIDESYNTHASE (Streptomycescoelicolor) |
PF00195(Chal_sti_synt_N) | 5 | ALA A 370LEU A 310ALA A 359LEU A 389VAL A 243 | None | 0.87A | 2bxeA-3v7iA:undetectable | 2bxeA-3v7iA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vly | NITRITE REDUCTASE (Nicotianatabacum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | ALA A 278LEU A 335GLU A 320LEU A 260VAL A 261 | None | 1.06A | 2bxeA-3vlyA:undetectable | 2bxeA-3vlyA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vre | HEMOGLOBIN SUBUNITALPHA (Mammuthusprimigenius) |
PF00042(Globin) | 5 | ALA A 69LEU A 76SER A 84LEU A 136VAL A 135 | None | 1.14A | 2bxeA-3vreA:2.0 | 2bxeA-3vreA:14.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ay7 | METHYLCOBALAMIN:COENZYME MMETHYLTRANSFERASE (Methanosarcinamazei) |
PF01208(URO-D) | 5 | ALA A 182ALA A 185LEU A 118LEU A 81ALA A 84 | None | 0.65A | 2bxeA-4ay7A:undetectable | 2bxeA-4ay7A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b2q | ATP SYNTHASE SUBUNITDELTA, MITOCHONDRIAL (Saccharomycescerevisiae) |
PF02823(ATP-synt_DE_N) | 5 | ALA H 87LEU H 16ALA H 90LEU H 32VAL H 57 | None | 1.07A | 2bxeA-4b2qH:undetectable | 2bxeA-4b2qH:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eff | AROMATIC-AMINO-ACIDAMINOTRANSFERASE (Burkholderiapseudomallei) |
PF00155(Aminotran_1_2) | 5 | ALA A 113LEU A 277LEU A 260ALA A 100LEU A 109 | None | 0.99A | 2bxeA-4effA:undetectable | 2bxeA-4effA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0l | AMIDOHYDROLASE (Brucellaabortus) |
PF01979(Amidohydro_1) | 5 | ALA A 149ALA A 147LEU A 199LEU A 157ALA A 205 | None | 1.06A | 2bxeA-4f0lA:undetectable | 2bxeA-4f0lA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f8x | ENDO-1,4-BETA-XYLANASE (Penicilliumcanescens) |
PF00331(Glyco_hydro_10) | 5 | PHE A 180ALA A 183ALA A 187LEU A 191LEU A 201 | None | 1.19A | 2bxeA-4f8xA:undetectable | 2bxeA-4f8xA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fqd | NIKO PROTEIN (Streptomycestendae) |
PF00275(EPSP_synthase) | 5 | ALA A 45ALA A 43LEU A 228LEU A 201ALA A 204 | None | 0.92A | 2bxeA-4fqdA:undetectable | 2bxeA-4fqdA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fqd | NIKO PROTEIN (Streptomycestendae) |
PF00275(EPSP_synthase) | 5 | ALA A 45LEU A 228LEU A 201ALA A 204LEU A 111 | None | 1.04A | 2bxeA-4fqdA:undetectable | 2bxeA-4fqdA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g3n | DNA GYRASE SUBUNIT A (Mycobacteriumtuberculosis) |
PF03989(DNA_gyraseA_C) | 5 | ALA A 732LEU A 803ALA A 776LEU A 762VAL A 763 | None | 1.13A | 2bxeA-4g3nA:undetectable | 2bxeA-4g3nA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gr4 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceslydicus) |
PF00501(AMP-binding)PF03621(MbtH) | 5 | ALA A 341ALA A 343LEU A 352ALA A 328VAL A 370 | None | 1.20A | 2bxeA-4gr4A:undetectable | 2bxeA-4gr4A:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gr5 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceslydicus) |
PF00501(AMP-binding)PF03621(MbtH) | 5 | ALA A 341ALA A 343LEU A 352ALA A 328VAL A 370 | None | 1.13A | 2bxeA-4gr5A:undetectable | 2bxeA-4gr5A:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 12 (Thermusthermophilus) |
PF00361(Proton_antipo_M)PF00662(Proton_antipo_N) | 5 | PHE L 323ALA L 326ALA L 330LEU L 334LEU L 449 | None | 1.19A | 2bxeA-4heaL:undetectable | 2bxeA-4heaL:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hpp | PROBABLE GLUTAMINESYNTHETASE (Pseudomonasaeruginosa) |
PF00120(Gln-synt_C)PF16952(Gln-synt_N_2) | 5 | ALA A 345ALA A 348LEU A 404LEU A 277ALA A 276 | None | 0.80A | 2bxeA-4hppA:undetectable | 2bxeA-4hppA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hst | GLUTARYL-7-AMINOCEPHALOSPORANIC ACIDACYLASE BETA CHAIN (Pseudomonas) |
PF01804(Penicil_amidase) | 5 | ALA B 402ALA B 406LEU B 410LEU B 315ALA B 335 | None | 1.10A | 2bxeA-4hstB:undetectable | 2bxeA-4hstB:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ib2 | PUTATIVE LIPOPROTEIN ([Ruminococcus]gnavus) |
PF03180(Lipoprotein_9) | 5 | PHE A 86LEU A 257LEU A 52ALA A 55VAL A 68 | None | 0.90A | 2bxeA-4ib2A:undetectable | 2bxeA-4ib2A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovj | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Alicyclobacillusacidocaldarius) |
PF13416(SBP_bac_8) | 5 | ALA A 389ALA A 385LEU A 381LEU A 302ALA A 163 | None | 1.00A | 2bxeA-4ovjA:undetectable | 2bxeA-4ovjA:21.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 8 | PHE A 206ALA A 210ALA A 213LEU A 331LEU A 347SER A 480LEU A 481VAL A 482 | NoneNoneNPS A 602 (-3.3A)NoneNPS A 602 ( 4.2A)NoneNoneNone | 0.59A | 2bxeA-4po0A:45.5 | 2bxeA-4po0A:74.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 8 | PHE A 206ALA A 213LEU A 331LEU A 347GLU A 354SER A 480LEU A 481VAL A 482 | NoneNPS A 602 (-3.3A)NoneNPS A 602 ( 4.2A)NPS A 602 ( 4.9A)NoneNoneNone | 0.62A | 2bxeA-4po0A:45.5 | 2bxeA-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u1f | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT B (Saccharomycescerevisiae) |
PF08662(eIF2A) | 5 | PHE A 342ALA A 381LEU A 334ALA A 331VAL A 319 | None | 1.15A | 2bxeA-4u1fA:undetectable | 2bxeA-4u1fA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uer | EIF3B (Lachanceakluyveri) |
PF00318(Ribosomal_S2) | 5 | PHE b 408ALA b 447LEU b 400ALA b 397VAL b 385 | None | 1.16A | 2bxeA-4uerb:undetectable | 2bxeA-4uerb:21.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 9 | PHE A 205ALA A 209ALA A 212LEU A 330LEU A 346ALA A 349GLU A 353SER A 479LEU A 480 | NoneCZE A 613 ( 4.4A)CZE A 613 ( 3.7A)CZE A 613 ( 4.2A)CZE A 613 ( 3.8A)CZE A 613 ( 4.7A)CZE A 613 (-2.9A)NoneNone | 0.64A | 2bxeA-5dqfA:46.1 | 2bxeA-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7p | CELL DIVISIONCONTROL PROTEINCDC48 (Mycolicibacteriumsmegmatis) |
PF00004(AAA)PF02359(CDC48_N) | 5 | LEU A 639LEU A 610ALA A 591LEU A 570VAL A 567 | None | 1.10A | 2bxeA-5e7pA:2.4 | 2bxeA-5e7pA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ed7 | TEGUMENT PROTEINUL21 (Humanalphaherpesvirus1) |
PF03252(Herpes_UL21) | 5 | ALA A 401ALA A 404LEU A 459LEU A 435VAL A 520 | None | 1.00A | 2bxeA-5ed7A:2.5 | 2bxeA-5ed7A:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ees | 4-HYDROXY-TETRAHYDRODIPICOLINATEREDUCTASE (Corynebacteriumglutamicum) |
PF01113(DapB_N)PF05173(DapB_C) | 5 | LEU A 102LEU A 242ALA A 104LEU A 113VAL A 112 | None | 1.24A | 2bxeA-5eesA:undetectable | 2bxeA-5eesA:18.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 10 | PHE A 206ALA A 210ALA A 213LEU A 331LEU A 347ALA A 350GLU A 354SER A 480LEU A 481VAL A 482 | None | 0.69A | 2bxeA-5ghkA:45.7 | 2bxeA-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2p | ARYLESTERASE (Sulfolobussolfataricus) |
PF07859(Abhydrolase_3) | 5 | ALA A 85ALA A 157LEU A 161ALA A 125LEU A 88 | None | 0.80A | 2bxeA-5l2pA:undetectable | 2bxeA-5l2pA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n3u | PHYCOCYANOBILINLYASE SUBUNIT ALPHA (Nostoc sp. PCC7120) |
no annotation | 5 | ALA A 38LEU A 26LEU A 55ALA A 58SER A 111 | None | 1.09A | 2bxeA-5n3uA:undetectable | 2bxeA-5n3uA:9.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 9 | PHE A 205ALA A 209ALA A 212LEU A 330LEU A 346ALA A 349GLU A 353SER A 479LEU A 480 | None | 0.45A | 2bxeA-5oriA:45.7 | 2bxeA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 9 | PHE A 205ALA A 209ALA A 212LEU A 330LEU A 346ALA A 349SER A 479LEU A 480VAL A 481 | None | 0.49A | 2bxeA-5oriA:45.7 | 2bxeA-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ux5 | BIFUNCTIONAL PROTEINPROLINE UTILIZATIONA (PUTA) (Corynebacteriumfreiburgense) |
PF00171(Aldedh)PF01619(Pro_dh) | 5 | ALA A 625ALA A 628LEU A 529ALA A 558GLU A 554 | None | 0.63A | 2bxeA-5ux5A:undetectable | 2bxeA-5ux5A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ux5 | BIFUNCTIONAL PROTEINPROLINE UTILIZATIONA (PUTA) (Corynebacteriumfreiburgense) |
PF00171(Aldedh)PF01619(Pro_dh) | 5 | ALA A 625ALA A 628LEU A 529LEU A 600ALA A 558 | None | 0.71A | 2bxeA-5ux5A:undetectable | 2bxeA-5ux5A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v72 | NADPH-DEPENDENTGLYOXYLATE/HYDROXYPYRUVATE REDUCTASE (Sinorhizobiummeliloti) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | ALA A 251LEU A 243LEU A 239SER A 232VAL A 234 | None | 1.15A | 2bxeA-5v72A:undetectable | 2bxeA-5v72A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xpz | FERMITIN FAMILYHOMOLOG 2 (Mus musculus) |
PF00373(FERM_M) | 5 | ALA A 86ALA A 88LEU A 90LEU A 20VAL A 35 | None | 0.95A | 2bxeA-5xpzA:3.1 | 2bxeA-5xpzA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yg7 | RIBOSE1,5-BISPHOSPHATEISOMERASE (Pyrococcushorikoshii) |
no annotation | 5 | PHE A 106ALA A 32ALA A 34LEU A 61ALA A 13 | None | 1.15A | 2bxeA-5yg7A:2.5 | 2bxeA-5yg7A:10.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 9 | PHE A 206ALA A 210ALA A 213LEU A 331LEU A 347ALA A 350GLU A 354LEU A 481VAL A 482 | None | 0.48A | 2bxeA-5yxeA:46.6 | 2bxeA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 8 | PHE A 206LEU A 331LEU A 347ALA A 350GLU A 354SER A 480LEU A 481VAL A 482 | None | 0.56A | 2bxeA-5yxeA:46.6 | 2bxeA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c6l | V-TYPE PROTON ATPASESUBUNIT C' (Saccharomycescerevisiae) |
no annotation | 5 | PHE D 18ALA D 21ALA D 25LEU D 29LEU D 103 | None | 1.19A | 2bxeA-6c6lD:undetectable | 2bxeA-6c6lD:9.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT EMONOVALENT CATION/H+ANTIPORTER SUBUNIT FMONOVALENT CATION/H+ANTIPORTER SUBUNIT G (Pyrococcusfuriosus) |
no annotation | 5 | ALA C 98ALA C 95LEU A 123LEU C 35VAL B 32 | None | 1.24A | 2bxeA-6cfwC:3.8 | 2bxeA-6cfwC:7.86 |