SIMILAR PATTERNS OF AMINO ACIDS FOR 2BXE_A_1FLA2001_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a0j | TRYPSIN (Salmo salar) |
PF00089(Trypsin) | 5 | LEU A 163ILE A 162VAL A 199GLY A 211LEU A 160 | None | 0.98A | 2bxeA-1a0jA:undetectable | 2bxeA-1a0jA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a70 | FERREDOXIN (Spinaciaoleracea) |
PF00111(Fer2) | 5 | ILE A 24VAL A 74GLY A 49LEU A 56SER A 83 | None | 1.30A | 2bxeA-1a70A:undetectable | 2bxeA-1a70A:10.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1atg | PERIPLASMICMOLYBDATE-BINDINGPROTEIN (Azotobactervinelandii) |
PF13531(SBP_bac_11) | 5 | LEU A 161ILE A 108VAL A 125GLY A 122LEU A 100 | None | 1.27A | 2bxeA-1atgA:undetectable | 2bxeA-1atgA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cg8 | PROTEIN (HEMOGLOBIN) (Dasyatis akajei) |
PF00042(Globin) | 5 | LEU A 16ILE A 17ASN A 20GLY A 25LEU A 110 | None | 1.08A | 2bxeA-1cg8A:2.0 | 2bxeA-1cg8A:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cqj | SUCCINYL-COASYNTHETASE ALPHACHAIN (Escherichiacoli) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 5 | ILE A 93VAL A 175GLY A 176CYH A 123LEU A 3 | None | 1.09A | 2bxeA-1cqjA:undetectable | 2bxeA-1cqjA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hn0 | CHONDROITIN ABCLYASE I (Proteusvulgaris) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF09092(Lyase_N)PF09093(Lyase_catalyt) | 5 | LEU A 519ILE A 520GLY A 531LEU A 481SER A 450 | None | 1.40A | 2bxeA-1hn0A:2.7 | 2bxeA-1hn0A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ipa | RNA 2'-O-RIBOSEMETHYLTRANSFERASE (Thermusthermophilus) |
PF00588(SpoU_methylase)PF08032(SpoU_sub_bind) | 5 | ARG A 20VAL A 147GLY A 149LEU A 130SER A 155 | None | 1.36A | 2bxeA-1ipaA:undetectable | 2bxeA-1ipaA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lqt | FPRA (Mycobacteriumtuberculosis) |
PF07992(Pyr_redox_2) | 5 | ARG A 96TYR A 97VAL A 84GLY A 85LEU A 39 | NoneNoneFAD A2457 (-3.6A)FAD A2457 ( 4.7A)None | 1.25A | 2bxeA-1lqtA:undetectable | 2bxeA-1lqtA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t90 | PROBABLEMETHYLMALONATE-SEMIALDEHYDEDEHYDROGENASE (Bacillussubtilis) |
PF00171(Aldedh) | 5 | LEU A 191VAL A 105GLY A 108CYH A 160LEU A 86 | None | 1.27A | 2bxeA-1t90A:0.0 | 2bxeA-1t90A:22.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ILE A 388ASN A 391ARG A 410LYS A 414GLY A 434 | None | 1.16A | 2bxeA-1tf0A:47.5 | 2bxeA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 8 | LEU A 387ILE A 388ASN A 391TYR A 411LYS A 414GLY A 434LEU A 453SER A 489 | None | 0.78A | 2bxeA-1tf0A:47.5 | 2bxeA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 8 | LEU A 387ILE A 388TYR A 411LYS A 414VAL A 433GLY A 434LEU A 453SER A 489 | None | 0.78A | 2bxeA-1tf0A:47.5 | 2bxeA-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wck | BCLA PROTEIN (Bacillusanthracis) |
PF01391(Collagen) | 5 | LEU A 167ILE A 174VAL A 105LEU A 200SER A 146 | None | 1.22A | 2bxeA-1wckA:undetectable | 2bxeA-1wckA:14.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xjv | PROTECTION OFTELOMERES 1 (Homo sapiens) |
PF02765(POT1)PF16686(POT1PC) | 5 | LEU A 239ILE A 241VAL A 222LEU A 181SER A 237 | None | 1.31A | 2bxeA-1xjvA:undetectable | 2bxeA-1xjvA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8t | HYPOTHETICAL PROTEINRV0983 (Mycobacteriumtuberculosis) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | ILE A 216VAL A 91GLY A 82LEU A 45SER A 185 | None | 1.38A | 2bxeA-1y8tA:undetectable | 2bxeA-1y8tA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aeh | FOCAL ADHESIONKINASE 1 (Gallus gallus) |
PF00373(FERM_M) | 5 | LEU A 223ILE A 224GLY A 172CYH A 173LEU A 211 | None | 1.34A | 2bxeA-2aehA:undetectable | 2bxeA-2aehA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b4v | RNA EDITING COMPLEXPROTEIN MP57 (Trypanosomabrucei) |
PF01909(NTP_transf_2)PF03828(PAP_assoc) | 5 | LEU A 280ILE A 281ASN A 277VAL A 87GLY A 84 | None | 1.34A | 2bxeA-2b4vA:undetectable | 2bxeA-2b4vA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cje | DUTPASE (Leishmaniamajor) |
PF08761(dUTPase_2) | 5 | LEU A 209ASN A 206ARG A 186TYR A 196VAL A 203 | NoneDUN A1266 (-3.7A)DUN A1266 (-3.0A)NoneNone | 1.16A | 2bxeA-2cjeA:undetectable | 2bxeA-2cjeA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eek | TRYPSIN-1 (Gadus morhua) |
PF00089(Trypsin) | 5 | LEU A 163ILE A 162VAL A 199GLY A 211LEU A 160 | None | 0.99A | 2bxeA-2eekA:undetectable | 2bxeA-2eekA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ell | ACIDIC LEUCINE-RICHNUCLEARPHOSPHOPROTEIN 32FAMILY MEMBER B (Homo sapiens) |
PF14580(LRR_9) | 5 | LEU A 67ILE A 41VAL A 59GLY A 60LEU A 56 | None | 1.27A | 2bxeA-2ellA:undetectable | 2bxeA-2ellA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f4w | UBIQUITIN-CONJUGATING ENZYME E2, J2 (Homo sapiens) |
PF00179(UQ_con) | 5 | LEU A 93ILE A 78ARG A 86TYR A 56GLY A 117 | None | 1.31A | 2bxeA-2f4wA:undetectable | 2bxeA-2f4wA:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i15 | HYPOTHETICAL PROTEINMG296 HOMOLOG (Mycoplasmapneumoniae) |
PF09644(Mg296) | 5 | LEU A 97ILE A 101VAL A 125GLY A 120SER A 65 | None | 1.16A | 2bxeA-2i15A:undetectable | 2bxeA-2i15A:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j0j | FOCAL ADHESIONKINASE 1 (Gallus gallus) |
PF00373(FERM_M)PF07714(Pkinase_Tyr) | 5 | LEU A 223ILE A 224GLY A 172CYH A 173LEU A 211 | None | 1.34A | 2bxeA-2j0jA:undetectable | 2bxeA-2j0jA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l5o | PUTATIVE THIOREDOXIN (Neisseriameningitidis) |
PF08534(Redoxin) | 5 | LEU A 62ILE A 30VAL A 95GLY A 96LEU A 10 | None | 1.31A | 2bxeA-2l5oA:undetectable | 2bxeA-2l5oA:13.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p6r | AFUHEL308 HELICASE (Archaeoglobusfulgidus) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | LEU A 128ILE A 129VAL A 139LEU A 72SER A 101 | None | 1.23A | 2bxeA-2p6rA:undetectable | 2bxeA-2p6rA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pff | FATTY ACID SYNTHASESUBUNIT BETA (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF16073(SAT) | 5 | LEU B 443ILE B 439VAL B 308GLY B 307CYH B 310 | None | 1.26A | 2bxeA-2pffB:undetectable | 2bxeA-2pffB:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q49 | PROBABLEN-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Arabidopsisthaliana) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | LEU A 36ILE A 32VAL A 109CYH A 89LEU A 340 | None | 1.41A | 2bxeA-2q49A:undetectable | 2bxeA-2q49A:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r8w | AGR_C_1641P (Agrobacteriumfabrum) |
PF00701(DHDPS) | 5 | LEU A 184ILE A 190VAL A 155GLY A 157LEU A 135 | None | 1.30A | 2bxeA-2r8wA:undetectable | 2bxeA-2r8wA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rhq | PHENYLALANYL-TRNASYNTHETASE ALPHACHAINPHENYLALANYL-TRNASYNTHETASE BETACHAIN (Staphylococcushaemolyticus) |
PF01409(tRNA-synt_2d)PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 5 | ILE B 620VAL B 628GLY B 627LEU B 515SER A 105 | None | 1.16A | 2bxeA-2rhqB:undetectable | 2bxeA-2rhqB:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdv | MYC-INDUCED NUCLEARANTIGEN (Homo sapiens) |
PF08007(Cupin_4) | 5 | LEU A 33ILE A 150ARG A 68VAL A 254LEU A 80 | None | 1.16A | 2bxeA-2xdvA:undetectable | 2bxeA-2xdvA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xt0 | HALOALKANEDEHALOGENASE (Plesiocystispacifica) |
PF00561(Abhydrolase_1) | 5 | ILE A 213ARG A 103GLY A 222LEU A 128SER A 104 | NoneNoneSO4 A1298 (-3.0A)NoneNone | 1.36A | 2bxeA-2xt0A:undetectable | 2bxeA-2xt0A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zns | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 1 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 5 | LEU A 770ILE A 767VAL A 751GLY A 750LEU A 456 | None | 1.20A | 2bxeA-2znsA:undetectable | 2bxeA-2znsA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ab0 | BCLA PROTEIN (Bacillusanthracis) |
no annotation | 5 | LEU A 167ILE A 174VAL A 105LEU A 200SER A 146 | None | 1.34A | 2bxeA-3ab0A:undetectable | 2bxeA-3ab0A:11.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3av6 | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Mus musculus) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 5 | LEU A 598ASN A 696VAL A 658GLY A 657CYH A 662 | NoneNoneNoneNone ZN A2002 (-2.1A) | 1.33A | 2bxeA-3av6A:undetectable | 2bxeA-3av6A:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctz | XAA-PROAMINOPEPTIDASE 1 (Homo sapiens) |
PF00557(Peptidase_M24)PF01321(Creatinase_N)PF16188(Peptidase_M24_C)PF16189(Creatinase_N_2) | 5 | LEU A 235ILE A 263VAL A 247LEU A 211SER A 224 | None | 1.36A | 2bxeA-3ctzA:undetectable | 2bxeA-3ctzA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fbs | OXIDOREDUCTASE (Agrobacteriumfabrum) |
PF07992(Pyr_redox_2) | 5 | ILE A 105ARG A 289GLY A 280CYH A 263LEU A 21 | None | 1.37A | 2bxeA-3fbsA:undetectable | 2bxeA-3fbsA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fqd | 5'-3'EXORIBONUCLEASE 2 (Schizosaccharomycespombe) |
PF03159(XRN_N) | 5 | ILE A 394TYR A 617VAL A 387GLY A 388LEU A 344 | None | 1.39A | 2bxeA-3fqdA:undetectable | 2bxeA-3fqdA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h0l | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A (Aquifexaeolicus) |
PF01425(Amidase) | 5 | LEU A 89ILE A 88VAL A 348GLY A 345LEU A 314 | None | 1.27A | 2bxeA-3h0lA:undetectable | 2bxeA-3h0lA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ig3 | PLXNA3 PROTEIN (Mus musculus) |
PF08337(Plexin_cytopl) | 5 | LEU A1391ILE A1392ASN A1395LEU A1406SER A1411 | None | 1.18A | 2bxeA-3ig3A:undetectable | 2bxeA-3ig3A:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ltw | ARYLAMINEN-ACETYLTRANSFERASENAT (Mycobacteriummarinum) |
PF00797(Acetyltransf_2) | 5 | LEU A 266ILE A 270GLY A 223CYH A 274LEU A 249 | None | 1.14A | 2bxeA-3ltwA:undetectable | 2bxeA-3ltwA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o3m | BETA SUBUNIT2-HYDROXYACYL-COADEHYDRATASE (Clostridioidesdifficile) |
PF06050(HGD-D) | 5 | ILE B 43VAL B 51GLY B 52CYH B 33LEU B 49 | None | 1.28A | 2bxeA-3o3mB:undetectable | 2bxeA-3o3mB:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o59 | DNA POLYMERASE IILARGE SUBUNIT (Pyrococcushorikoshii) |
PF03833(PolC_DP2) | 5 | ILE X 125VAL X 164GLY X 165LEU X 110SER X 153 | None | 1.05A | 2bxeA-3o59X:2.1 | 2bxeA-3o59X:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ovg | AMIDOHYDROLASE (Mycoplasmasynoviae) |
PF02126(PTE) | 5 | LEU A 258TYR A 223VAL A 233GLY A 232LEU A 235 | None | 1.41A | 2bxeA-3ovgA:undetectable | 2bxeA-3ovgA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pwz | SHIKIMATEDEHYDROGENASE 3 (Pseudomonasputida) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 5 | LEU A 23ILE A 20VAL A 239GLY A 240LEU A 267 | None | 1.37A | 2bxeA-3pwzA:undetectable | 2bxeA-3pwzA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pxi | NEGATIVE REGULATOROF GENETICCOMPETENCE CLPC/MECB (Bacillussubtilis) |
PF00004(AAA)PF02151(UVR)PF02861(Clp_N)PF07724(AAA_2)PF10431(ClpB_D2-small) | 5 | LEU A 725ILE A 722ARG A 556VAL A 549GLY A 548 | None | 1.11A | 2bxeA-3pxiA:undetectable | 2bxeA-3pxiA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qhp | TYPE 1 CAPSULARPOLYSACCHARIDEBIOSYNTHESIS PROTEINJ (CAPJ) (Helicobacterpylori) |
PF00534(Glycos_transf_1) | 5 | ILE A 289VAL A 208GLY A 209LEU A 268SER A 296 | None | 1.29A | 2bxeA-3qhpA:undetectable | 2bxeA-3qhpA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qxm | GLUTAMATE RECEPTORIONOTROPIC, KAINATE2 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 5 | LEU A 754ILE A 751VAL A 735GLY A 734LEU A 439 | None | 1.15A | 2bxeA-3qxmA:undetectable | 2bxeA-3qxmA:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 5 | ILE A 516VAL A 580GLY A 584LEU A 536SER A 607 | None | 1.18A | 2bxeA-3r75A:undetectable | 2bxeA-3r75A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 5 | LEU A 512ILE A 516VAL A 586GLY A 602LEU A 536 | None | 1.14A | 2bxeA-3r75A:undetectable | 2bxeA-3r75A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r8e | HYPOTHETICAL SUGARKINASE (Cytophagahutchinsonii) |
PF00480(ROK) | 5 | LEU A 233ILE A 236VAL A 141GLY A 140LEU A 242 | None | 1.21A | 2bxeA-3r8eA:undetectable | 2bxeA-3r8eA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rr1 | PUTATIVED-GALACTONATEDEHYDRATASE (Ralstoniapickettii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 182ILE A 208ARG A 166VAL A 188LEU A 196 | None | 1.35A | 2bxeA-3rr1A:undetectable | 2bxeA-3rr1A:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ryt | PLEXIN-A1 (Mus musculus) |
PF08337(Plexin_cytopl) | 5 | LEU A1413ILE A1414ASN A1417LEU A1428SER A1433 | None | 0.98A | 2bxeA-3rytA:undetectable | 2bxeA-3rytA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqg | METHYL-COENZYME MREDUCTASE, BETASUBUNIT (unculturedarchaeon) |
PF02241(MCR_beta)PF02783(MCR_beta_N) | 5 | LEU B 47ILE B 75VAL B 155GLY B 154LEU B 133 | None | 1.31A | 2bxeA-3sqgB:undetectable | 2bxeA-3sqgB:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbh | O-ACETYL SERINESULFHYDRYLASE (Leishmaniadonovani) |
PF00291(PALP) | 5 | LEU A 244ILE A 245VAL A 185GLY A 184LEU A 240 | NoneNoneLLP A 51 ( 4.2A)NoneNone | 1.16A | 2bxeA-3tbhA:undetectable | 2bxeA-3tbhA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqs | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE A (Coxiellaburnetii) |
PF00398(RrnaAD) | 5 | LEU A 21ILE A 24LYS A 73VAL A 104GLY A 105 | None | 1.21A | 2bxeA-3tqsA:undetectable | 2bxeA-3tqsA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqs | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE A (Coxiellaburnetii) |
PF00398(RrnaAD) | 5 | LEU A 21ILE A 24VAL A 104GLY A 105LEU A 50 | None | 1.18A | 2bxeA-3tqsA:undetectable | 2bxeA-3tqsA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tyj | BCLA PROTEIN (Bacillusanthracis) |
no annotation | 5 | LEU A 167ILE A 174VAL A 105LEU A 200SER A 146 | None | 1.21A | 2bxeA-3tyjA:undetectable | 2bxeA-3tyjA:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbj | GALACTOSIDEO-ACETYLTRANSFERASE (Bacillus cereus) |
PF00132(Hexapep) | 5 | LEU A 23ASN A 21VAL A 18GLY A 19LEU A 10 | None | 1.26A | 2bxeA-3vbjA:undetectable | 2bxeA-3vbjA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ast | ALDO-KETO REDUCTASEAKR14A1 (Escherichiacoli) |
PF00248(Aldo_ket_red) | 5 | TYR A 170VAL A 217GLY A 218CYH A 18LEU A 189 | None | 1.08A | 2bxeA-4astA:undetectable | 2bxeA-4astA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4evq | PUTATIVE ABCTRANSPORTER SUBUNIT,SUBSTRATE-BINDINGCOMPONENT (Rhodopseudomonaspalustris) |
PF13458(Peripla_BP_6) | 5 | LEU A 49ILE A 53ASN A 130TYR A 178GLY A 105 | NoneNonePHB A 406 (-3.7A)PHB A 406 ( 4.3A)None | 1.35A | 2bxeA-4evqA:undetectable | 2bxeA-4evqA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4io6 | AVGLUR1 LIGANDBINDING DOMAIN (Adineta vaga) |
PF00497(SBP_bac_3) | 5 | LEU A 226ILE A 225ASN A 100GLY A 208LEU A 234 | NoneNone CL A 303 (-3.1A)NoneNone | 1.41A | 2bxeA-4io6A:undetectable | 2bxeA-4io6A:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jgg | ESTERASE TESA (Pseudomonasaeruginosa) |
PF13472(Lipase_GDSL_2) | 5 | LEU A 107ILE A 109VAL A 146GLY A 147LEU A 168 | None | 1.41A | 2bxeA-4jggA:undetectable | 2bxeA-4jggA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0q | MEMBRANE-ASSOCIATEDPROTEIN VP24 (Zaireebolavirus) |
PF06389(Filo_VP24) | 5 | LEU A 152ILE A 153ASN A 156GLY A 101LEU A 119 | None | 1.11A | 2bxeA-4m0qA:undetectable | 2bxeA-4m0qA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0i | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF01425(Amidase) | 5 | LEU A 69ILE A 68VAL A 331GLY A 328LEU A 297 | None | 1.33A | 2bxeA-4n0iA:undetectable | 2bxeA-4n0iA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o89 | RNA 3'-TERMINALPHOSPHATE CYCLASE (Pyrococcushorikoshii) |
PF01137(RTC)PF05189(RTC_insert) | 5 | LEU A 132ILE A 149VAL A 168GLY A 147LEU A 103 | None | 1.28A | 2bxeA-4o89A:undetectable | 2bxeA-4o89A:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4obs | ALPHA-L-IDURONIDASE (Homo sapiens) |
PF01229(Glyco_hydro_39) | 5 | LEU A 353VAL A 88GLY A 51LEU A 74SER A 67 | None | 1.10A | 2bxeA-4obsA:undetectable | 2bxeA-4obsA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4obu | PYRIDOXAL-DEPENDENTDECARBOXYLASE DOMAINPROTEIN ([Ruminococcus]gnavus) |
no annotation | 5 | ILE E 164ASN E 163VAL E 156GLY E 158SER E 299 | NonePLP E 501 ( 4.4A)NonePLP E 501 ( 4.3A)None | 1.32A | 2bxeA-4obuE:undetectable | 2bxeA-4obuE:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4obu | PYRIDOXAL-DEPENDENTDECARBOXYLASE DOMAINPROTEIN ([Ruminococcus]gnavus) |
no annotation | 5 | LEU E 167ILE E 164ASN E 163VAL E 156GLY E 158 | NoneNonePLP E 501 ( 4.4A)NonePLP E 501 ( 4.3A) | 1.32A | 2bxeA-4obuE:undetectable | 2bxeA-4obuE:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oj5 | TAILSPIKE PROTEIN (Escherichiavirus CBA120) |
no annotation | 5 | ILE A 389VAL A 341GLY A 340LEU A 354SER A 261 | None | 0.76A | 2bxeA-4oj5A:undetectable | 2bxeA-4oj5A:21.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 8 | LEU A 387ASN A 391ARG A 410TYR A 411VAL A 433GLY A 434LEU A 453SER A 489 | NPS A 601 ( 4.7A)NPS A 601 (-4.3A)NPS A 601 (-4.5A)NPS A 601 (-4.3A)NoneNoneNPS A 601 (-4.7A)NPS A 601 (-3.1A) | 0.60A | 2bxeA-4po0A:45.5 | 2bxeA-4po0A:74.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 8 | LEU A 387ASN A 391TYR A 411LYS A 414VAL A 433GLY A 434LEU A 453SER A 489 | NPS A 601 ( 4.7A)NPS A 601 (-4.3A)NPS A 601 (-4.3A)NPS A 601 (-2.7A)NoneNoneNPS A 601 (-4.7A)NPS A 601 (-3.1A) | 0.58A | 2bxeA-4po0A:45.5 | 2bxeA-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uxd | 2-DEHYDRO-3-DEOXY-D-GLUCONATE/2-DEHYDRO-3-DEOXY-PHOSPHOGLUCONATE ALDOLASE (Picrophilustorridus) |
PF00701(DHDPS) | 5 | LEU A 121ILE A 120VAL A 75GLY A 76SER A 154 | None | 0.95A | 2bxeA-4uxdA:undetectable | 2bxeA-4uxdA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 5 | LEU A 110ILE A 690ASN A 15VAL A 701SER A 302 | None | 1.20A | 2bxeA-4wd9A:2.3 | 2bxeA-4wd9A:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj7 | MALCAVERNIN (Homo sapiens) |
no annotation | 5 | LEU A 155ILE A 139VAL A 216GLY A 214LEU A 115 | None | 1.41A | 2bxeA-4wj7A:undetectable | 2bxeA-4wj7A:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ydi | ENVELOPEGLYCOPROTEIN GP160 (Humanimmunodeficiencyvirus 1) |
PF00516(GP120) | 5 | LEU G 342ASN G 339VAL G 333LEU G 390SER G 393 | None | 1.30A | 2bxeA-4ydiG:undetectable | 2bxeA-4ydiG:17.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 9 | LEU A 386ASN A 390ARG A 409TYR A 410LYS A 413VAL A 432GLY A 433LEU A 452SER A 488 | None | 0.75A | 2bxeA-5dqfA:46.1 | 2bxeA-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dt5 | BETA-GLUCOSIDASE (Exiguobacteriumantarcticum) |
PF00232(Glyco_hydro_1) | 5 | LEU A 194ILE A 251GLY A 215CYH A 286LEU A 218 | None | 1.33A | 2bxeA-5dt5A:undetectable | 2bxeA-5dt5A:21.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 9 | LEU A 387ASN A 391ARG A 410TYR A 411LYS A 414VAL A 433GLY A 434LEU A 453SER A 489 | None | 0.52A | 2bxeA-5ghkA:45.7 | 2bxeA-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijl | DNA POLYMERASE IILARGE SUBUNIT (Pyrococcusabyssi) |
PF03833(PolC_DP2) | 5 | ILE A 122VAL A 161GLY A 162LEU A 107SER A 150 | None | 1.04A | 2bxeA-5ijlA:undetectable | 2bxeA-5ijlA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | LEU A 374ILE A 370VAL A 364GLY A 365LEU A 489 | None | 1.42A | 2bxeA-5ip9A:3.9 | 2bxeA-5ip9A:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringae groupgenomosp. 3) |
no annotation | 5 | LEU A 206ILE A 203GLY A 124CYH A 175LEU A 101 | None | 1.08A | 2bxeA-5iuwA:undetectable | 2bxeA-5iuwA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jc8 | PUTATIVE SHORT-CHAINDEHYDROGENASE/REDUCTASE (Paraburkholderiaxenovorans) |
PF13561(adh_short_C2) | 5 | LEU A 95ILE A 145ASN A 97GLY A 175LEU A 134 | None | 1.38A | 2bxeA-5jc8A:undetectable | 2bxeA-5jc8A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jc8 | PUTATIVE SHORT-CHAINDEHYDROGENASE/REDUCTASE (Paraburkholderiaxenovorans) |
PF13561(adh_short_C2) | 5 | LEU A 95ILE A 145VAL A 178GLY A 175LEU A 134 | None | 1.27A | 2bxeA-5jc8A:undetectable | 2bxeA-5jc8A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jff | PROBABLE ADENOSINEMONOPHOSPHATE-PROTEIN TRANSFERASE FIC (Escherichiacoli) |
PF02661(Fic) | 5 | LEU A 134ILE A 131ARG A 78GLY A 142LEU A 59 | None | 1.40A | 2bxeA-5jffA:undetectable | 2bxeA-5jffA:16.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jzd | ISOCHORISMATESYNTHASE ENTC (Escherichiacoli) |
PF00425(Chorismate_bind) | 5 | ARG A 347VAL A 149GLY A 363LEU A 304SER A 195 | ISC A 401 (-3.5A)NoneISC A 401 (-3.3A)ISC A 401 ( 4.4A)None | 1.07A | 2bxeA-5jzdA:undetectable | 2bxeA-5jzdA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5och | - (-) |
no annotation | 5 | LEU B 274ILE B 270VAL B 219GLY B 220LEU B 148 | None | 1.38A | 2bxeA-5ochB:undetectable | 2bxeA-5ochB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ohs | - (-) |
no annotation | 5 | ARG A 283VAL A 138GLY A 137LEU A 494SER A 279 | NSQ A 709 (-3.3A)NoneNoneMPD A 705 ( 4.5A)MPD A 705 ( 3.9A) | 1.14A | 2bxeA-5ohsA:undetectable | 2bxeA-5ohsA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 8 | ILE A 387ARG A 409TYR A 410LYS A 413VAL A 432GLY A 433LEU A 452SER A 488 | None | 0.75A | 2bxeA-5oriA:45.7 | 2bxeA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 8 | ILE A 387ASN A 390ARG A 409TYR A 410LYS A 413GLY A 433LEU A 452SER A 488 | None | 0.74A | 2bxeA-5oriA:45.7 | 2bxeA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 8 | LEU A 386ILE A 387ASN A 390TYR A 410LYS A 413GLY A 433LEU A 452SER A 488 | None | 0.97A | 2bxeA-5oriA:45.7 | 2bxeA-5oriA:74.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 8 | LEU A 386ILE A 387TYR A 410LYS A 413VAL A 432GLY A 433LEU A 452SER A 488 | None | 0.99A | 2bxeA-5oriA:45.7 | 2bxeA-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2o | J30 CCH (Thermobacilluscomposti) |
no annotation | 5 | LEU A 95VAL A 100GLY A 99CYH A 114LEU A 184 | NoneNoneNone ZN A 606 (-2.3A)None | 1.33A | 2bxeA-5u2oA:undetectable | 2bxeA-5u2oA:9.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ukw | GLUCOSE-6-PHOSPHATE1-DEHYDROGENASE (Homo sapiens) |
PF00479(G6PD_N)PF02781(G6PD_C) | 5 | ILE A 355VAL A 499GLY A 500CYH A 232LEU A 495 | None | 1.38A | 2bxeA-5ukwA:undetectable | 2bxeA-5ukwA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vey | HISTONE H2B TYPE1-J,HISTONE H2A TYPE1-B/E (Homo sapiens) |
PF00125(Histone)PF16211(Histone_H2A_C) | 5 | LEU A 140ILE A 70VAL A 132GLY A 133LEU A 123 | None | 1.33A | 2bxeA-5veyA:2.3 | 2bxeA-5veyA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vzt | F-BOX ONLY PROTEIN31 (Homo sapiens) |
no annotation | 5 | LEU B 138ILE B 194VAL B 162GLY B 171LEU B 146 | None | 1.28A | 2bxeA-5vztB:undetectable | 2bxeA-5vztB:11.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 5 | LEU A 787ASN A 791TYR A 616VAL A 795GLY A 794 | None | 1.19A | 2bxeA-5welA:undetectable | 2bxeA-5welA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNIT (Komagataellaphaffii) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | LEU A 375ILE A 371VAL A 365GLY A 366LEU A 490 | None | 1.41A | 2bxeA-5xogA:4.2 | 2bxeA-5xogA:15.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 7 | ASN A 391ARG A 410LYS A 414VAL A 433GLY A 434LEU A 453SER A 489 | None | 0.99A | 2bxeA-5yxeA:46.6 | 2bxeA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 8 | LEU A 387ASN A 391TYR A 411LYS A 414VAL A 433GLY A 434LEU A 453SER A 489 | None | 0.82A | 2bxeA-5yxeA:46.6 | 2bxeA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0d | AMIDASE,HYDANTOINASE/CARBAMOYLASE FAMILY (Paraburkholderiaphymatum) |
no annotation | 5 | LEU A 20ILE A 98ARG A 43VAL A 120GLY A 79 | None | 1.39A | 2bxeA-6c0dA:undetectable | 2bxeA-6c0dA:9.12 |