SIMILAR PATTERNS OF AMINO ACIDS FOR 2BM9_C_SAMC301_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d8l | PROTEIN (HOLLIDAYJUNCTION DNAHELICASE RUVA) (Escherichiacoli) |
PF01330(RuvA_N)PF14520(HHH_5) | 5 | LEU A 71LEU A 139ASN A 100ALA A 101ALA A 109 | None | 1.16A | 2bm9C-1d8lA:undetectable | 2bm9C-1d8lA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1itk | CATALASE-PEROXIDASE (Haloarculamarismortui) |
PF00141(peroxidase) | 5 | LEU A 511LEU A 458GLY A 538ALA A 467ALA A 471 | None | 0.87A | 2bm9C-1itkA:undetectable | 2bm9C-1itkA:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ixp | PYRIDOXINE5'-PHOSPHATESYNTHASE (Escherichiacoli) |
PF03740(PdxJ) | 5 | LEU A 65GLU A 211GLY A 7ALA A 39ALA A 37 | None | 1.06A | 2bm9C-1ixpA:undetectable | 2bm9C-1ixpA:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 5 | GLY B 302ASN B 112ASN B 304ALA B 305ALA B 46 | None | 1.03A | 2bm9C-1jtdB:undetectable | 2bm9C-1jtdB:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k72 | ENDOGLUCANASE 9G ([Clostridium]cellulolyticum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 5 | LEU A 305LEU A 314TYR A 351ALA A 321ALA A 324 | None | 1.05A | 2bm9C-1k72A:undetectable | 2bm9C-1k72A:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nne | DNA MISMATCH REPAIRPROTEIN MUTS (Thermusaquaticus) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 5 | LEU A 527LEU A 372GLU A 368GLY A 367ARG A 308 | None | 1.16A | 2bm9C-1nneA:undetectable | 2bm9C-1nneA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o70 | FASCICLIN I (Drosophilamelanogaster) |
PF02469(Fasciclin) | 5 | LEU A 544LEU A 496GLY A 607TYR A 505ASN A 606 | None | 0.99A | 2bm9C-1o70A:undetectable | 2bm9C-1o70A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofu | CELL DIVISIONPROTEIN FTSZ (Pseudomonasaeruginosa) |
PF00091(Tubulin)PF12327(FtsZ_C) | 5 | LEU A 255GLY A 227ASN A 247ALA A 244ALA A 240 | None | 1.19A | 2bm9C-1ofuA:3.1 | 2bm9C-1ofuA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1otk | PHENYLACETIC ACIDDEGRADATION PROTEINPAAC (Escherichiacoli) |
PF05138(PaaA_PaaC) | 6 | LEU A 142LEU A 209ASN A 147ASN A 205ALA A 202ALA A 198 | None | 1.23A | 2bm9C-1otkA:undetectable | 2bm9C-1otkA:24.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qlb | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Wolinellasuccinogenes) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | LYS A 27GLU A 422GLY A 421ALA A 20ALA A 16 | NoneNoneNoneNoneFAD A1656 (-3.4A) | 1.16A | 2bm9C-1qlbA:undetectable | 2bm9C-1qlbA:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qsa | PROTEIN (SOLUBLELYTICTRANSGLYCOSYLASESLT70) (Escherichiacoli) |
PF01464(SLT)PF14718(SLT_L) | 5 | LEU A 128LEU A 142LYS A 141ASN A 107ALA A 104 | None | 1.19A | 2bm9C-1qsaA:undetectable | 2bm9C-1qsaA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t5j | HYPOTHETICAL PROTEINMJ1187 (Methanocaldococcusjannaschii) |
PF03747(ADP_ribosyl_GH) | 5 | LEU A 139GLY A 132ASN A 137ALA A 167ALA A 163 | None | 1.08A | 2bm9C-1t5jA:undetectable | 2bm9C-1t5jA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t92 | GENERAL SECRETIONPATHWAY PROTEIN G (Klebsiellapneumoniae) |
PF08334(T2SSG) | 5 | LEU A 89LEU A 43GLY A 63ALA A 66ALA A 70 | None | 1.18A | 2bm9C-1t92A:undetectable | 2bm9C-1t92A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u2l | PEROXIDASE/CATALASEHPI (Escherichiacoli) |
PF00141(peroxidase) | 5 | LEU A 513LEU A 462GLY A 533ALA A 471ALA A 475 | None | 0.93A | 2bm9C-1u2lA:undetectable | 2bm9C-1u2lA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uaa | PROTEIN(ATP-DEPENDENT DNAHELICASE REP.) (Escherichiacoli) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | LEU A 453LEU A 445GLU A 423GLY A 422ALA A 425 | None | 1.15A | 2bm9C-1uaaA:2.4 | 2bm9C-1uaaA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc6 | BETA-GALACTOSIDASE (Penicillium sp.) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 5 | LEU A 342LEU A 340GLY A 387TYR A 329ALA A 87 | None | 1.03A | 2bm9C-1xc6A:undetectable | 2bm9C-1xc6A:13.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk7 | MERCURIC REDUCTASE (Pseudomonasaeruginosa) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | GLU A 34GLY A 11ASN A 272ALA A 16ALA A 19 | FAD A 666 (-2.5A)FAD A 666 (-3.2A)SO4 A2002 (-3.8A)NoneNone | 1.13A | 2bm9C-1zk7A:3.2 | 2bm9C-1zk7A:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zvu | TOPOISOMERASE IVSUBUNIT A (Escherichiacoli) |
PF00521(DNA_topoisoIV)PF03989(DNA_gyraseA_C) | 5 | LEU A 38LEU A 99ASN A 167ALA A 85ALA A 81 | None | 1.11A | 2bm9C-1zvuA:undetectable | 2bm9C-1zvuA:16.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2br4 | CEPHALOSPORINHYDROXYLASE CMCI (Streptomycesclavuligerus) |
PF04989(CmcI) | 11 | LEU A 18LEU A 64LYS A 65GLU A 87GLY A 89TYR A 91ASN A 92ARG A 121CYH A 139ALA A 161ALA A 163 | SAM A 301 ( 4.4A)SAM A 301 (-4.2A)SAM A 301 (-2.6A)SAM A 301 (-3.0A)SAM A 301 (-3.3A)SAM A 301 (-4.3A)NoneSAM A 301 (-3.1A)SAM A 301 (-2.9A)SAM A 301 (-3.6A)SAM A 301 ( 3.7A) | 0.50A | 2bm9C-2br4A:34.5 | 2bm9C-2br4A:99.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cu2 | PUTATIVEMANNOSE-1-PHOSPHATEGUANYLYL TRANSFERASE (Thermusthermophilus) |
PF00483(NTP_transferase) | 5 | LEU A 215LEU A 89GLY A 227ARG A 214ALA A 226 | None | 1.05A | 2bm9C-2cu2A:undetectable | 2bm9C-2cu2A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cx9 | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | LEU A 22GLY A 83TYR A 81ALA A 86ALA A 90 | None | 0.90A | 2bm9C-2cx9A:undetectable | 2bm9C-2cx9A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6k | TRANSKETOLASE (Thermusthermophilus) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | LEU A 400LEU A 370GLY A 415ASN A 417ALA A 439 | None | 1.16A | 2bm9C-2e6kA:undetectable | 2bm9C-2e6kA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6m | WERNER SYNDROMEATP-DEPENDENTHELICASE HOMOLOG (Mus musculus) |
PF01612(DNA_pol_A_exo1) | 5 | LEU A 155GLY A 74CYH A 103ALA A 211ALA A 208 | None | 1.01A | 2bm9C-2e6mA:undetectable | 2bm9C-2e6mA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ep5 | 350AA LONGHYPOTHETICALASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Sulfurisphaeratokodaii) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | LEU A 325GLY A 305ASN A 328ASN A 301ALA A 302 | None | 1.08A | 2bm9C-2ep5A:undetectable | 2bm9C-2ep5A:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fbv | WERNER SYNDROMEHELICASE (Homo sapiens) |
PF01612(DNA_pol_A_exo1) | 5 | LEU A 161GLY A 80CYH A 109ALA A 217ALA A 214 | None | 1.06A | 2bm9C-2fbvA:undetectable | 2bm9C-2fbvA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h6r | TRIOSEPHOSPHATEISOMERASE (Methanocaldococcusjannaschii) |
PF00121(TIM) | 5 | LEU A 87GLU A 138GLY A 176ASN A 6ALA A 193 | None | 1.09A | 2bm9C-2h6rA:undetectable | 2bm9C-2h6rA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hoq | PUTATIVEHAD-HYDROLASE PH1655 (Pyrococcushorikoshii) |
PF13419(HAD_2) | 5 | LEU A 65LEU A 36GLY A 81ALA A 27ALA A 23 | None | 1.01A | 2bm9C-2hoqA:3.4 | 2bm9C-2hoqA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ibp | CITRATE SYNTHASE (Pyrobaculumaerophilum) |
PF00285(Citrate_synt) | 5 | LEU A 208GLY A 182TYR A 62ASN A 186ALA A 185 | None | 1.09A | 2bm9C-2ibpA:undetectable | 2bm9C-2ibpA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iq1 | PROTEIN PHOSPHATASE2C KAPPA, PPM1K (Homo sapiens) |
PF00481(PP2C) | 5 | LEU A 258LEU A 269GLY A 265CYH A 138ALA A 190 | None | 1.17A | 2bm9C-2iq1A:undetectable | 2bm9C-2iq1A:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oap | TYPE II SECRETIONSYSTEM PROTEIN (Archaeoglobusfulgidus) |
PF00437(T2SSE) | 6 | LEU 1 426GLU 1 412ASN 1 370ASN 1 414ALA 1 394ALA 1 263 | None | 1.38A | 2bm9C-2oap1:undetectable | 2bm9C-2oap1:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ogx | MOLYBDENUM STORAGEPROTEIN SUBUNITALPHA (Azotobactervinelandii) |
PF00696(AA_kinase) | 5 | LEU A 116GLY A 79ASN A 112ALA A 109ALA A 106 | NoneATP A 281 (-3.2A)NoneNone W A2015 (-4.2A) | 1.11A | 2bm9C-2ogxA:undetectable | 2bm9C-2ogxA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pge | MENC (Desulfotaleapsychrophila) |
PF13378(MR_MLE_C) | 5 | LEU A 81LEU A 85GLY A 44ALA A 128ALA A 124 | None | 0.92A | 2bm9C-2pgeA:undetectable | 2bm9C-2pgeA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rek | PUTATIVE TETR-FAMILYTRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
PF00440(TetR_N) | 5 | LEU A 74LEU A 132GLY A 102ARG A 70ALA A 99 | None | 1.03A | 2bm9C-2rekA:undetectable | 2bm9C-2rekA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vfv | XYLITOL OXIDASE (Streptomycescoelicolor) |
PF01565(FAD_binding_4)PF04030(ALO) | 5 | LEU A 174LEU A 90GLY A 83ALA A 113ALA A 117 | NoneNoneSFD A1418 ( 4.3A)SFD A1418 (-3.5A)SFD A1418 (-3.2A) | 1.02A | 2bm9C-2vfvA:undetectable | 2bm9C-2vfvA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xfg | ENDOGLUCANASE 1 (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9) | 5 | LEU A 308LEU A 317TYR A 354ALA A 324ALA A 327 | None | 1.09A | 2bm9C-2xfgA:undetectable | 2bm9C-2xfgA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yev | CYTOCHROME C OXIDASEPOLYPEPTIDE I+III (Thermusthermophilus) |
PF00115(COX1)PF00510(COX3) | 5 | LEU A 168LEU A 206GLY A 630ALA A 210ALA A 214 | None | 1.19A | 2bm9C-2yevA:undetectable | 2bm9C-2yevA:15.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfq | NAD-SPECIFICGLUTAMATEDEHYDROGENASE (Peptoniphilusasaccharolyticus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | LYS A 94GLY A 324ASN A 323ALA A 322ALA A 300 | None | 1.15A | 2bm9C-2yfqA:undetectable | 2bm9C-2yfqA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yr5 | PRO-ENZYME OFL-PHENYLALANINEOXIDASE (Pseudomonas sp.P-501) |
no annotation | 5 | LEU A 389GLY A 63TYR A 93ALA A 409ALA A 650 | NoneFAD A 801 (-3.1A)NoneNoneNone | 0.97A | 2bm9C-2yr5A:undetectable | 2bm9C-2yr5A:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9x | SELENOCYSTEINE LYASE (Rattusnorvegicus) |
PF00266(Aminotran_5) | 5 | LEU A 226LEU A 241GLY A 75ALA A 71ALA A 68 | None | 1.17A | 2bm9C-3a9xA:2.2 | 2bm9C-3a9xA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1a | HEMOGLOBIN SUBUNITALPHA-1/2 (Capra hircus) |
PF00042(Globin) | 5 | LEU A 109GLY A 18ASN A 20ALA A 21ALA A 64 | None | 1.18A | 2bm9C-3d1aA:undetectable | 2bm9C-3d1aA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e39 | PUTATIVENITROREDUCTASE (Desulfovibrioalaskensis) |
PF00881(Nitroreductase) | 5 | GLY A 37CYH A 49ASN A 106ALA A 103ALA A 100 | None | 0.96A | 2bm9C-3e39A:undetectable | 2bm9C-3e39A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e73 | LANC-LIKE PROTEIN 1 (Homo sapiens) |
PF05147(LANC_like) | 5 | GLY A 327TYR A 319ASN A 328ALA A 329ALA A 348 | None | 1.18A | 2bm9C-3e73A:undetectable | 2bm9C-3e73A:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5s | METHYLENETETRAHYDROFOLATE--TRNA-(URACIL-5-)-METHYLTRANSFERASE TRMFO (Thermusthermophilus) |
PF01134(GIDA) | 5 | LEU A 375GLY A 354ASN A 356ALA A 353ALA A 333 | None | 1.16A | 2bm9C-3g5sA:undetectable | 2bm9C-3g5sA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gtz | PUTATIVE TRANSLATIONINITIATION INHIBITOR (Salmonellaenterica) |
PF01042(Ribonuc_L-PSP) | 5 | LEU A 31TYR A 104ASN A 101ALA A 35ALA A 75 | None | 1.05A | 2bm9C-3gtzA:undetectable | 2bm9C-3gtzA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrd | NICOTINATEDEHYDROGENASE MEDIUMMOLYBDOPTERINSUBUNIT (Eubacteriumbarkeri) |
PF02738(Ald_Xan_dh_C2) | 5 | LEU B 61LEU B 108GLY B 158ALA B 100ALA B 96 | None | 1.08A | 2bm9C-3hrdB:undetectable | 2bm9C-3hrdB:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kb3 | PROTEIN PHOSPHATASE2C 16 (Arabidopsisthaliana) |
PF00481(PP2C) | 5 | LEU B 394LEU B 405GLY B 401CYH B 254ALA B 329 | None | 1.14A | 2bm9C-3kb3B:undetectable | 2bm9C-3kb3B:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldh | LACTATEDEHYDROGENASE (Squalusacanthias) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | LEU A 66LEU A 41GLY A 33ALA A 35ALA A 248 | None | 1.16A | 2bm9C-3ldhA:2.5 | 2bm9C-3ldhA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m0g | FARNESYL DIPHOSPHATESYNTHASE (Rhodobactercapsulatus) |
PF00348(polyprenyl_synt) | 5 | LEU A 277LEU A 48TYR A 204ALA A 191ALA A 196 | None | 1.08A | 2bm9C-3m0gA:undetectable | 2bm9C-3m0gA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rht | (GATASE1)-LIKEPROTEIN (Planctopiruslimnophila) |
PF07090(GATase1_like) | 5 | GLU A 86GLY A 93TYR A 88ASN A 152ALA A 58 | None | 1.09A | 2bm9C-3rhtA:undetectable | 2bm9C-3rhtA:24.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rk6 | POLYADENYLATE-BINDINGPROTEIN-INTERACTINGPROTEIN 1 (Homo sapiens) |
PF02854(MIF4G) | 5 | LEU A 243LEU A 225GLU A 223GLY A 220ALA A 214 | None | 1.10A | 2bm9C-3rk6A:undetectable | 2bm9C-3rk6A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uqe | 6-PHOSPHOFRUCTOKINASE ISOZYME 2 (Escherichiacoli) |
PF00294(PfkB) | 5 | LEU A 183GLY A 279CYH A 295ALA A 261ALA A 47 | None | 1.04A | 2bm9C-3uqeA:2.8 | 2bm9C-3uqeA:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ut2 | CATALASE-PEROXIDASE2 (Magnaportheoryzae) |
PF00141(peroxidase) | 5 | LEU A 564LEU A 511GLY A 590ALA A 520ALA A 524 | None | 0.89A | 2bm9C-3ut2A:undetectable | 2bm9C-3ut2A:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxo | CATALASE-PEROXIDASE (Synechococcuselongatus) |
PF00141(peroxidase) | 5 | LEU A 510LEU A 457GLY A 529ALA A 466ALA A 470 | None | 0.99A | 2bm9C-3wxoA:undetectable | 2bm9C-3wxoA:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b18 | IMPORTIN SUBUNITALPHA-1 (Homo sapiens) |
PF00514(Arm)PF16186(Arm_3) | 5 | LEU A 208GLY A 194ASN A 238ALA A 235ALA A 232 | None | 1.06A | 2bm9C-4b18A:undetectable | 2bm9C-4b18A:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1o | BETA-XYLOSIDASE (Parageobacillusthermoglucosidasius) |
PF03512(Glyco_hydro_52) | 5 | LEU A 230LEU A 110GLY A 69TYR A 67ALA A 181 | None | 1.07A | 2bm9C-4c1oA:undetectable | 2bm9C-4c1oA:14.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c51 | CATALASE-PEROXIDASE (Mycobacteriumtuberculosis) |
PF00141(peroxidase) | 5 | LEU A 521LEU A 467GLY A 548ALA A 476ALA A 480 | None | 0.86A | 2bm9C-4c51A:undetectable | 2bm9C-4c51A:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4da1 | PROTEIN PHOSPHATASE1K, MITOCHONDRIAL (Homo sapiens) |
PF00481(PP2C) | 5 | LEU A 258LEU A 269GLY A 265CYH A 138ALA A 190 | None | 1.19A | 2bm9C-4da1A:undetectable | 2bm9C-4da1A:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4doe | 1,4-BETA-GLUCANASE (Caldicellulosiruptorbescii) |
PF00759(Glyco_hydro_9) | 5 | LEU A 328LEU A 337TYR A 374ALA A 344ALA A 347 | None | 1.05A | 2bm9C-4doeA:undetectable | 2bm9C-4doeA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dyo | ASPARTYLAMINOPEPTIDASE (Homo sapiens) |
PF02127(Peptidase_M18) | 5 | LEU A 224LEU A 228GLY A 138ALA A 137ALA A 243 | None | 1.17A | 2bm9C-4dyoA:undetectable | 2bm9C-4dyoA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ern | TFIIH BASALTRANSCRIPTION FACTORCOMPLEX HELICASE XPBSUBUNIT (Homo sapiens) |
PF16203(ERCC3_RAD25_C) | 5 | LEU A 701GLU A 697GLY A 695ARG A 553ALA A 694 | None | 1.19A | 2bm9C-4ernA:3.6 | 2bm9C-4ernA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6t | MOLYBDENUM STORAGEPROTEIN SUBUNITALPHA (Azotobactervinelandii) |
PF00696(AA_kinase) | 5 | LEU A 116GLY A 79ASN A 112ALA A 109ALA A 106 | NoneATP A 301 (-3.2A)NoneNone8M0 A 303 (-3.3A) | 1.13A | 2bm9C-4f6tA:undetectable | 2bm9C-4f6tA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jz6 | SALICYLALDEHYDEDEHYDROGENASE NAHF (Pseudomonasputida) |
PF00171(Aldedh) | 5 | LEU A 278GLY A 98ASN A 100ALA A 97ALA A 87 | None | 1.04A | 2bm9C-4jz6A:3.6 | 2bm9C-4jz6A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k17 | LEUCINE-RICHREPEAT-CONTAININGPROTEIN 16A (Mus musculus) |
PF13516(LRR_6) | 5 | LEU A 577GLY A 572ASN A 602ALA A 598ALA A 596 | None | 1.09A | 2bm9C-4k17A:undetectable | 2bm9C-4k17A:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kv7 | PROBABLELEUCINE/ISOLEUCINE/VALINE-BINDINGPROTEIN (Rhodopirellulabaltica) |
PF13458(Peripla_BP_6) | 5 | LEU A 315LEU A 337GLY A 343ALA A 77ALA A 81 | None | 1.13A | 2bm9C-4kv7A:4.2 | 2bm9C-4kv7A:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l01 | TYROSINE-PROTEINKINASE JAK1 (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | LEU A 702LEU A 737GLY A 713CYH A 763ALA A 760 | None | 1.19A | 2bm9C-4l01A:undetectable | 2bm9C-4l01A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lls | GERANYLTRANSTRANSFERASE (Roseobacterdenitrificans) |
PF00348(polyprenyl_synt) | 5 | LEU A 277LEU A 47TYR A 204ALA A 191ALA A 196 | None | 1.15A | 2bm9C-4llsA:undetectable | 2bm9C-4llsA:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnr | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Eggerthellalenta) |
PF00905(Transpeptidase) | 5 | GLU A 349GLY A 348ASN A 347ALA A 346ALA A 102 | None | 1.17A | 2bm9C-4mnrA:undetectable | 2bm9C-4mnrA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mup | AMIDOHYDROLASE (Agrobacteriumfabrum) |
PF04909(Amidohydro_2) | 5 | GLY A 70ASN A 240ASN A 71ALA A 72ALA A 35 | None | 1.09A | 2bm9C-4mupA:undetectable | 2bm9C-4mupA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbq | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE (Coxiellaburnetii) |
PF00013(KH_1)PF00575(S1)PF01138(RNase_PH)PF03725(RNase_PH_C)PF03726(PNPase) | 5 | LEU A 98LEU A 148GLY A 138ALA A 136ALA A 29 | None | 1.16A | 2bm9C-4nbqA:undetectable | 2bm9C-4nbqA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oli | NON-RECEPTORTYROSINE-PROTEINKINASE TYK2 (Homo sapiens) |
PF07714(Pkinase_Tyr) | 6 | LEU A 722LEU A 757GLY A 733CYH A 783ASN A 734ALA A 780 | None | 1.34A | 2bm9C-4oliA:undetectable | 2bm9C-4oliA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ou2 | 2-AMINOMUCONATE6-SEMIALDEHYDEDEHYDROGENASE (Pseudomonasfluorescens) |
PF00171(Aldedh) | 5 | LEU A 204LEU A 172ASN A 124ALA A 180ALA A 184 | None | 1.16A | 2bm9C-4ou2A:3.1 | 2bm9C-4ou2A:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0f | SERINE PROTEASEINHIBITOR 4, ISOFORMB (Drosophilamelanogaster) |
PF00079(Serpin) | 5 | LEU A 270GLU A 326GLY A 327ASN A 324ALA A 330 | None | 1.12A | 2bm9C-4p0fA:undetectable | 2bm9C-4p0fA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pzk | TRNA(CYTIDINE(34)-2'-O)-METHYLTRANSFERASE (Bacillusanthracis) |
PF00588(SpoU_methylase) | 5 | LEU A 7LEU A 136GLY A 17ALA A 20ALA A 24 | NoneSAH A 201 ( 4.3A)NoneNoneNone | 1.18A | 2bm9C-4pzkA:undetectable | 2bm9C-4pzkA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qxf | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 4, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF01462(LRRNT)PF11921(DUF3439)PF13855(LRR_8) | 5 | LEU A 62LEU A 55GLU A 53ALA A 76ALA A 100 | None | 1.06A | 2bm9C-4qxfA:undetectable | 2bm9C-4qxfA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r16 | 418AA LONGHYPOTHETICALUDP-N-ACETYL-D-MANNOSAMINURONIC ACIDDEHYDROGENASE (Pyrococcushorikoshii) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 55LEU A 59GLY A 28ASN A 40ALA A 16 | None | 1.15A | 2bm9C-4r16A:4.5 | 2bm9C-4r16A:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3w | 2-AMINOMUCONATE6-SEMIALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 5 | LEU A 199LEU A 167ASN A 119ALA A 175ALA A 179 | None | 1.14A | 2bm9C-4u3wA:undetectable | 2bm9C-4u3wA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uad | IMPORTIN SUBUNITALPHA-7 (Homo sapiens) |
PF00514(Arm)PF16186(Arm_3) | 5 | LEU A 206GLY A 192ASN A 236ALA A 233ALA A 230 | None | 1.10A | 2bm9C-4uadA:undetectable | 2bm9C-4uadA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wov | NON-RECEPTORTYROSINE-PROTEINKINASE TYK2 (Homo sapiens) |
PF07714(Pkinase_Tyr) | 6 | LEU A 722LEU A 757GLY A 733CYH A 783ASN A 734ALA A 780 | NoneNoneNoneNoneSO4 A 903 (-4.1A)None | 1.36A | 2bm9C-4wovA:undetectable | 2bm9C-4wovA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wyr | ACETYL-COAACETYLTRANSFERASE (Clostridiumacetobutylicum) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 21GLY A 30ASN A 117ALA A 33ALA A 37 | None | 1.10A | 2bm9C-4wyrA:undetectable | 2bm9C-4wyrA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xg0 | UNCHARACTERIZEDPROTEIN (Bordetellabronchiseptica) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | LEU A 296LEU A 324GLY A 332ALA A 331ALA A 233 | None | 1.17A | 2bm9C-4xg0A:undetectable | 2bm9C-4xg0A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z42 | UREASE SUBUNIT ALPHA (Yersiniaenterocolitica) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | LEU C 186LEU C 512GLU C 508GLY C 505ALA C 500 | None | 1.16A | 2bm9C-4z42C:undetectable | 2bm9C-4z42C:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp1 | MYCOCEROSIC ACIDSYNTHASE (Mycolicibacteriumsmegmatis) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | LEU A 32LEU A 28GLY A 358ALA A 362ALA A 410 | None | 1.05A | 2bm9C-5bp1A:undetectable | 2bm9C-5bp1A:13.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d8w | ENDOGLUCANASE (Ganodermalucidum) |
PF00150(Cellulase) | 5 | LEU A 104LEU A 51GLY A 312ASN A 313ALA A 30 | None | 1.10A | 2bm9C-5d8wA:undetectable | 2bm9C-5d8wA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gtk | BETAINE-ALDEHYDEDEHYDROGENASE (Bacillus cereus) |
PF00171(Aldedh) | 5 | LEU A 320GLY A 287ASN A 286ALA A 284ALA A 279 | None | 0.98A | 2bm9C-5gtkA:3.4 | 2bm9C-5gtkA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gwo | PROBABLE PROTEINPHOSPHATASE 2C 50 (Oryza sativa) |
PF00481(PP2C) | 5 | LEU A 268LEU A 279GLY A 275CYH A 129ALA A 203 | None | 1.11A | 2bm9C-5gwoA:undetectable | 2bm9C-5gwoA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gy0 | GLUCANASE (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 5 | LEU A 319LEU A 328TYR A 364ALA A 335ALA A 338 | None | 1.05A | 2bm9C-5gy0A:undetectable | 2bm9C-5gy0A:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irm | UNCHARACTERIZEDPROTEIN (Oryctolaguscuniculus) |
PF05729(NACHT)PF13516(LRR_6) | 5 | LEU A 968LEU A 983GLY A 958ALA A 928ALA A 926 | None | 1.13A | 2bm9C-5irmA:undetectable | 2bm9C-5irmA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjh | 4-ALPHA-GLUCANOTRANSFERASE (Corynebacteriumglutamicum) |
PF02446(Glyco_hydro_77) | 5 | LEU A 569LEU A 627GLU A 632GLY A 633ALA A 606 | None | 1.09A | 2bm9C-5jjhA:undetectable | 2bm9C-5jjhA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqi | CATALASE-PEROXIDASE (Burkholderiapseudomallei) |
PF00141(peroxidase) | 5 | LEU A 528LEU A 475GLY A 555ALA A 484ALA A 488 | None | 0.92A | 2bm9C-5kqiA:undetectable | 2bm9C-5kqiA:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kyo | CYP101J2 (Sphingobiumyanoikuyae) |
PF00067(p450) | 5 | LEU A 259LEU A 160GLY A 251CYH A 359ALA A 362 | NoneNoneHEM A 501 (-3.3A)HEM A 501 (-2.4A)None | 1.19A | 2bm9C-5kyoA:undetectable | 2bm9C-5kyoA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lnq | 3-KETOACYL-COATHIOLASE-LIKEPROTEIN (Leishmaniamexicana) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | LEU A 371GLY A 381ASN A 378ALA A 211ALA A 208 | None | 1.17A | 2bm9C-5lnqA:undetectable | 2bm9C-5lnqA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | 2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESISPROTEIN PHLC (Pseudomonasprotegens) |
no annotation | 5 | LEU C 360ASN C 337CYH C 277ASN C 382ALA C 240 | NoneNoneNoneSCY C 88 ( 3.5A)None | 1.09A | 2bm9C-5mg5C:undetectable | 2bm9C-5mg5C:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ndf | POLYPEPTIDEN-ACETYLGALACTOSAMINYLTRANSFERASE 2 (Homo sapiens) |
no annotation | 5 | LEU A 349GLU A 334GLY A 308ASN A 335ALA A 307 | NoneEDO A 604 (-2.8A)EDO A 604 (-3.7A)EDO A 604 ( 4.3A)EDO A 605 ( 3.4A) | 1.15A | 2bm9C-5ndfA:undetectable | 2bm9C-5ndfA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ok8 | LPP20 LIPOPROTEIN (Helicobacterpylori) |
no annotation | 5 | LEU A 137GLY A 67ASN A 92ALA A 89ALA A 85 | None | 1.11A | 2bm9C-5ok8A:undetectable | 2bm9C-5ok8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v7o | NOSK (Streptomycesactuosus) |
PF12697(Abhydrolase_6) | 5 | LEU A 64LEU A 104GLY A 100ALA A 109ALA A 113 | None | 1.15A | 2bm9C-5v7oA:2.6 | 2bm9C-5v7oA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x9w | DNA MISMATCH REPAIRPROTEIN MUTS (Neisseriagonorrhoeae) |
no annotation | 5 | LEU A 221LEU A 256GLY A 140ALA A 232ALA A 235 | None | 1.18A | 2bm9C-5x9wA:undetectable | 2bm9C-5x9wA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z06 | BDI_3064 PROTEIN (Parabacteroidesdistasonis) |
no annotation | 5 | LEU A 648LEU A 634GLY A 664ASN A 312ALA A 311 | None | 1.12A | 2bm9C-5z06A:undetectable | 2bm9C-5z06A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bn2 | ACETYL-COAACETYLTRANSFERASE (Elizabethkingiaanophelis) |
no annotation | 5 | LEU A 21GLY A 30ASN A 117ALA A 33ALA A 37 | None | 1.20A | 2bm9C-6bn2A:undetectable | 2bm9C-6bn2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d6q | EXOSOME COMPLEXCOMPONENT RRP42 (Homo sapiens) |
no annotation | 5 | LEU E 192GLY E 47ASN E 162ALA E 159ALA E 155 | None | 1.02A | 2bm9C-6d6qE:undetectable | 2bm9C-6d6qE:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eu2 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC3DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC6 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
no annotationno annotation | 5 | LEU P 269LEU P 265ASN P 295ALA O 497ALA O 504 | None | 1.16A | 2bm9C-6eu2P:undetectable | 2bm9C-6eu2P:undetectable |