SIMILAR PATTERNS OF AMINO ACIDS FOR 2BM9_A_SAMA301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1btc BETA-AMYLASE

(Glycine max) 		PF01373
(Glyco_hydro_14) 		3 LYS A 467
ASP A 140
ASN A 272
 None
 0.94A 2bm9A-1btcA:
undetectable		 2bm9A-1btcA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c1d L-PHENYLALANINE
DEHYDROGENASE

(Rhodococcus sp.) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 LYS A  66
ASP A  55
ASN A 262
 PHE  A 361 (-2.6A)
None
PHE  A 361 ( 3.1A)
 1.12A 2bm9A-1c1dA:
3.6		 2bm9A-1c1dA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1csy SYK PROTEIN TYROSINE
KINASE

(Homo sapiens) 		PF00017
(SH2) 		3 LYS A  69
ASP A  45
ASN A  47
 None
 0.94A 2bm9A-1csyA:
undetectable		 2bm9A-1csyA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1es6 MATRIX PROTEIN VP40

(Ebola virus sp.) 		PF07447
(VP40) 		3 LYS A 236
ASP A 194
ASN A 220
 None
 1.14A 2bm9A-1es6A:
undetectable		 2bm9A-1es6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcy ARTHROPODAN
HEMOCYANIN

(Panulirus
interruptus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 LYS A 127
ASP A  48
ASN A  91
 None
 1.02A 2bm9A-1hcyA:
undetectable		 2bm9A-1hcyA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kxh ALPHA-AMYLASE

(Pseudoalteromonas
haloplanktis) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C) 		3 LYS A 190
ASP A 146
ASN A 150
 None
 1.13A 2bm9A-1kxhA:
undetectable		 2bm9A-1kxhA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oc2 DTDP-GLUCOSE
4,6-DEHYDRATASE

(Streptococcus
suis) 		PF16363
(GDP_Man_Dehyd) 		3 LYS A 333
ASP A 279
ASN A 208
 None
 1.08A 2bm9A-1oc2A:
5.3		 2bm9A-1oc2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1orf GRANZYME A

(Homo sapiens) 		PF00089
(Trypsin) 		3 LYS A 104
ASP A  36
ASN A  59
 None
 1.14A 2bm9A-1orfA:
undetectable		 2bm9A-1orfA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p49 STERYL-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase)
PF14707
(Sulfatase_C) 		3 LYS A 556
ASP A 546
ASN A 551
 PO4  A 606 (-3.4A)
None
PO4  A 606 ( 4.9A)
 0.87A 2bm9A-1p49A:
undetectable		 2bm9A-1p49A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pp7 39 KDA INITIATOR
BINDING PROTEIN

(Trichomonas
vaginalis) 		PF10416
(IBD) 		3 LYS U  69
ASP U  89
ASN U  84
 None
 0.99A 2bm9A-1pp7U:
undetectable		 2bm9A-1pp7U:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s58 B19 PARVOVIRUS
CAPSID

(Primate
erythroparvovirus
1) 		PF00740
(Parvo_coat) 		3 LYS A 429
ASP A 434
ASN A 432
 None
 1.01A 2bm9A-1s58A:
undetectable		 2bm9A-1s58A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxj ACTIVATOR 1 95 KDA
SUBUNIT
ACTIVATOR 1 37 KDA
SUBUNIT

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF08519
(RFC1)
PF00004
(AAA)
PF08542
(Rep_fac_C) 		3 LYS B  55
ASP A 586
ASN B 145
 AGS  B 802 (-2.5A)
None
AGS  B 802 (-3.1A)
 1.12A 2bm9A-1sxjB:
2.5		 2bm9A-1sxjB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w33 BBCRASP-1

(Borreliella
burgdorferi) 		PF05714
(Borrelia_lipo_1) 		3 LYS A 141
ASP A 227
ASN A 222
 None
 1.08A 2bm9A-1w33A:
undetectable		 2bm9A-1w33A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvg CDP-GLUCOSE
4,6-DEHYDRATASE

(Salmonella
enterica) 		PF16363
(GDP_Man_Dehyd) 		3 LYS A 136
ASP A 203
ASN A 197
 CXY  A 401 (-2.8A)
None
CXY  A 401 (-2.9A)
 1.18A 2bm9A-1wvgA:
4.8		 2bm9A-1wvgA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE

(Sulfurisphaera
tokodaii) 		PF00294
(PfkB) 		3 LYS A  30
ASP A  59
ASN A  64
 None
 0.66A 2bm9A-1wyeA:
undetectable		 2bm9A-1wyeA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8c S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE

(Clostridium
acetobutylicum) 		PF13649
(Methyltransf_25) 		3 LYS A  31
ASP A 225
ASN A 229
 None
 1.14A 2bm9A-1y8cA:
10.8		 2bm9A-1y8cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5

(Homo sapiens) 		PF00025
(Arf) 		3 LYS A 126
ASP A  66
ASN A  26
 GDP  A 180 (-3.2A)
GDP  A 180 ( 4.3A)
GDP  A 180 (-3.2A)
 1.16A 2bm9A-1z6yA:
2.7		 2bm9A-1z6yA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2an1 PUTATIVE KINASE

(Salmonella
enterica) 		PF01513
(NAD_kinase) 		3 LYS A 284
ASP A 105
ASN A  97
 LYS  A 284 ( 0.0A)
ASP  A 105 ( 0.6A)
ASN  A  97 ( 0.6A)
 1.16A 2bm9A-2an1A:
2.8		 2bm9A-2an1A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atc ASPARTATE
CARBAMOYLTRANSFERASE
, CATALYTIC CHAIN

(Escherichia
coli) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 LYS A  31
ASP A 141
ASN A 286
 None
 1.14A 2bm9A-2atcA:
5.4		 2bm9A-2atcA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b6n PROTEINASE K

(Serratia sp.
GF96) 		PF00082
(Peptidase_S8) 		3 LYS A 260
ASP A  21
ASN A  17
 None
CA  A 300 (-3.1A)
None
 1.00A 2bm9A-2b6nA:
2.3		 2bm9A-2b6nA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bih NITRATE REDUCTASE
[NADPH]

(Ogataea angusta) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		3 LYS A 346
ASP A 468
ASN A 473
 None
 1.06A 2bm9A-2bihA:
undetectable		 2bm9A-2bihA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bii NITRATE REDUCTASE
[NADPH]

(Ogataea angusta) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		3 LYS A 346
ASP A 468
ASN A 473
 GOL  A 701 ( 4.9A)
None
None
 1.07A 2bm9A-2biiA:
undetectable		 2bm9A-2biiA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6s ADENOVIRUS 2,12
PENTON BASE CHIMERA

(Human
mastadenovirus
C) 		PF01686
(Adeno_Penton_B) 		3 LYS A 493
ASP A  78
ASN A  74
 None
 1.15A 2bm9A-2c6sA:
undetectable		 2bm9A-2c6sA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cje DUTPASE

(Leishmania
major) 		PF08761
(dUTPase_2) 		3 LYS A 179
ASP A  69
ASN A 206
 DUN  A1266 (-2.5A)
None
DUN  A1266 (-3.7A)
 0.96A 2bm9A-2cjeA:
undetectable		 2bm9A-2cjeA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3z BETA-GLUCOSIDASE

(Phanerochaete
chrysosporium) 		PF00232
(Glyco_hydro_1) 		3 LYS A  27
ASP A  64
ASN A  59
 None
 0.95A 2bm9A-2e3zA:
undetectable		 2bm9A-2e3zA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ehq 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE

(Thermus
thermophilus) 		PF00171
(Aldedh) 		3 LYS A 496
ASP A 293
ASN A 468
 None
 0.74A 2bm9A-2ehqA:
3.3		 2bm9A-2ehqA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ell ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER B

(Homo sapiens) 		PF14580
(LRR_9) 		3 LYS A  75
ASP A 153
ASN A 101
 None
 1.09A 2bm9A-2ellA:
undetectable		 2bm9A-2ellA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ics ADENINE DEAMINASE

(Enterococcus
faecalis) 		PF01979
(Amidohydro_1) 		3 LYS A 155
ASP A  88
ASN A 116
 KCX  A 154 ( 3.5A)
None
KCX  A 154 ( 4.3A)
 0.98A 2bm9A-2icsA:
undetectable		 2bm9A-2icsA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4o CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
pneumoniae) 		PF16555
(GramPos_pilinD1) 		3 LYS A  41
ASP A  50
ASN A 184
 None
 1.17A 2bm9A-2l4oA:
undetectable		 2bm9A-2l4oA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogj DIHYDROOROTASE

(Agrobacterium
fabrum) 		PF01979
(Amidohydro_1) 		3 LYS A 176
ASP A 105
ASN A 134
 KCX  A 175 ( 3.5A)
None
KCX  A 175 ( 4.1A)
 0.93A 2bm9A-2ogjA:
undetectable		 2bm9A-2ogjA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pg3 QUEUOSINE
BIOSYNTHESIS PROTEIN
QUEC

(Pectobacterium
atrosepticum) 		PF06508
(QueC) 		3 LYS A 227
ASP A 127
ASN A 164
 None
 0.99A 2bm9A-2pg3A:
2.2		 2bm9A-2pg3A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po2 PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2

(Pyrococcus
abyssi) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		3 LYS B 220
ASP B 146
ASN B 148
 None
 1.11A 2bm9A-2po2B:
undetectable		 2bm9A-2po2B:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq0 HYPOTHETICAL
CONSERVED PROTEIN
GK1056

(Geobacillus
kaustophilus) 		PF08282
(Hydrolase_3) 		3 LYS A 184
ASP A 176
ASN A 210
 None
 1.12A 2bm9A-2pq0A:
2.7		 2bm9A-2pq0A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qx2 SEX PHEROMONE
STAPH-CAM373

(Staphylococcus
aureus) 		PF07537
(CamS) 		3 LYS A 218
ASP A 328
ASN A 279
 None
 0.96A 2bm9A-2qx2A:
undetectable		 2bm9A-2qx2A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 LYS A 287
ASP A 275
ASN A 282
 None
 1.14A 2bm9A-2v4jA:
undetectable		 2bm9A-2v4jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2var FRUCTOKINASE

(Sulfolobus
solfataricus) 		PF00294
(PfkB) 		3 LYS A  30
ASP A  59
ASN A  64
 None
 0.68A 2bm9A-2varA:
2.9		 2bm9A-2varA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zam VACUOLAR PROTEIN
SORTING-ASSOCIATING
PROTEIN 4B

(Mus musculus) 		PF00004
(AAA)
PF09336
(Vps4_C) 		3 LYS A 180
ASP A 429
ASN A 279
 None
 0.98A 2bm9A-2zamA:
undetectable		 2bm9A-2zamA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbz CYTOCHROME P450-SU1

(Streptomyces
griseolus) 		PF00067
(p450) 		3 LYS A 178
ASP A 145
ASN A 400
 None
 0.98A 2bm9A-2zbzA:
undetectable		 2bm9A-2zbzA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahi XYLULOSE
5-PHOSPHATE/FRUCTOSE
6-PHOSPHATE
PHOSPHOKETOLASE

(Bifidobacterium
breve) 		PF03894
(XFP)
PF09363
(XFP_C)
PF09364
(XFP_N) 		3 LYS A 670
ASP A 702
ASN A 637
 EDO  A 830 (-3.4A)
EDO  A 829 (-3.2A)
EDO  A 830 ( 3.7A)
 1.05A 2bm9A-3ahiA:
2.2		 2bm9A-3ahiA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		3 LYS A  31
ASP A 686
ASN A 688
 None
 1.08A 2bm9A-3cskA:
undetectable		 2bm9A-3cskA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6t ASPARTATE
AMINOTRANSFERASE

(Lactobacillus
acidophilus) 		PF00155
(Aminotran_1_2) 		3 LYS A 156
ASP A 412
ASN A 403
 None
 0.99A 2bm9A-3f6tA:
2.9		 2bm9A-3f6tA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhn PROTEIN TRANSPORT
PROTEIN TIP20

(Saccharomyces
cerevisiae) 		PF04437
(RINT1_TIP1) 		3 LYS A 650
ASP A 620
ASN A 615
 None
 0.78A 2bm9A-3fhnA:
undetectable		 2bm9A-3fhnA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g79 NDP-N-ACETYL-D-GALAC
TOSAMINURONIC ACID
DEHYDROGENASE

(Methanosarcina
mazei) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		3 LYS A 296
ASP A 369
ASN A 372
 None
 1.01A 2bm9A-3g79A:
4.1		 2bm9A-3g79A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8

(Homo sapiens) 		PF00443
(UCH) 		3 LYS A 835
ASP A 813
ASN A 808
 None
 0.89A 2bm9A-3n3kA:
undetectable		 2bm9A-3n3kA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzt GLUTAMATE--CYSTEINE
LIGASE

(Francisella
tularensis) 		PF04262
(Glu_cys_ligase) 		3 LYS A 287
ASP A  47
ASN A 278
 SO4  A 508 (-2.7A)
SO4  A 506 ( 4.0A)
SO4  A 508 ( 3.4A)
 1.09A 2bm9A-3nztA:
undetectable		 2bm9A-3nztA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1

(Bacillus
halodurans) 		PF00171
(Aldedh) 		3 LYS A 495
ASP A 291
ASN A 467
 None
 0.80A 2bm9A-3qanA:
3.8		 2bm9A-3qanA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qtd PMBA PROTEIN

(Pseudomonas
aeruginosa) 		PF01523
(PmbA_TldD) 		3 LYS A 315
ASP A 308
ASN A 343
 None
 1.05A 2bm9A-3qtdA:
undetectable		 2bm9A-3qtdA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjl 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE

(Bacillus
licheniformis) 		PF00171
(Aldedh) 		3 LYS A 496
ASP A 292
ASN A 468
 None
 0.86A 2bm9A-3rjlA:
3.0		 2bm9A-3rjlA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rx8 CELLULASE

(Alicyclobacillus
acidocaldarius) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		3 LYS A 215
ASP A 293
ASN A 291
 None
 0.93A 2bm9A-3rx8A:
undetectable		 2bm9A-3rx8A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		3 LYS A 417
ASP A 275
ASN A 199
 None
 1.15A 2bm9A-3vuuA:
undetectable		 2bm9A-3vuuA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ypi TRIOSEPHOSPHATE
ISOMERASE

(Saccharomyces
cerevisiae) 		PF00121
(TIM) 		3 LYS A 195
ASP A 106
ASN A 148
 None
 0.96A 2bm9A-3ypiA:
undetectable		 2bm9A-3ypiA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zus BOTULINUM NEUROTOXIN
TYPE A,
SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 23

(Clostridium
botulinum;
Homo sapiens) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		3 LYS A 780
ASP A 270
ASN A 368
 None
 1.02A 2bm9A-3zusA:
undetectable		 2bm9A-3zusA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zvj THIOREDOXIN
PEROXIDASE

(Schistosoma
mansoni) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		3 LYS D 143
ASP D  75
ASN D 121
 None
 1.09A 2bm9A-3zvjD:
undetectable		 2bm9A-3zvjD:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aip FE-REGULATED PROTEIN
B

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 LYS A 248
ASP A 225
ASN A 101
 None
 1.11A 2bm9A-4aipA:
undetectable		 2bm9A-4aipA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bj6 RAP1-INTERACTING
FACTOR 2

(Saccharomyces
cerevisiae) 		no annotation 3 LYS A 380
ASP A 114
ASN A 254
 None
 1.10A 2bm9A-4bj6A:
2.8		 2bm9A-4bj6A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bl3 PENICILLIN BINDING
PROTEIN 2 PRIME

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
PF05223
(MecA_N) 		3 LYS A 280
ASP A 274
ASN A 260
 None
 0.86A 2bm9A-4bl3A:
undetectable		 2bm9A-4bl3A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4by4 FI18190P1

(Drosophila
melanogaster) 		PF00036
(EF-hand_1)
PF13499
(EF-hand_7) 		3 LYS A  63
ASP A 111
ASN A 123
 None
CA  A1185 (-2.7A)
None
 1.07A 2bm9A-4by4A:
undetectable		 2bm9A-4by4A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkb DEOXYURIDINE
TRIPHOSPHATASE

(Trypanosoma
brucei) 		PF08761
(dUTPase_2) 		3 LYS A 208
ASP A  69
ASN A 235
 DUN  A 303 (-2.5A)
None
DUN  A 303 (-3.9A)
 0.98A 2bm9A-4dkbA:
undetectable		 2bm9A-4dkbA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwe UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF15421
(Polysacc_deac_3) 		3 LYS A 145
ASP A 360
ASN A 351
 None
 1.09A 2bm9A-4dweA:
undetectable		 2bm9A-4dweA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4c MULTIDRUG RESISTANCE
PROTEIN PGP-1

(Caenorhabditis
elegans) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		3 LYS A1057
ASP A 846
ASN A 850
 None
 1.15A 2bm9A-4f4cA:
undetectable		 2bm9A-4f4cA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hdo KREV INTERACTION
TRAPPED PROTEIN 1

(Homo sapiens) 		PF00373
(FERM_M) 		3 LYS A 713
ASP A 498
ASN A 496
 None
 0.81A 2bm9A-4hdoA:
undetectable		 2bm9A-4hdoA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iel GLUTATHIONE
S-TRANSFERASE,
N-TERMINAL DOMAIN
PROTEIN

(Burkholderia
ambifaria) 		PF13417
(GST_N_3) 		3 LYS A  15
ASP A  94
ASN A  67
 GSH  A 301 ( 4.3A)
None
None
 1.07A 2bm9A-4ielA:
undetectable		 2bm9A-4ielA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3b M1 FAMILY
AMINOPEPTIDASE

(Plasmodium
falciparum) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		3 LYS A 380
ASP A 358
ASN A 356
 None
 1.19A 2bm9A-4j3bA:
undetectable		 2bm9A-4j3bA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kdx GLUTATHIONE
S-TRANSFERASE DOMAIN

(Paraburkholderia
graminis) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		3 LYS A  15
ASP A  94
ASN A  67
 GSH  A 301 ( 4.4A)
None
None
 1.08A 2bm9A-4kdxA:
undetectable		 2bm9A-4kdxA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l3f INTERNALIN K

(Listeria
monocytogenes) 		no annotation 3 LYS A  58
ASP A  48
ASN A  72
 None
 1.18A 2bm9A-4l3fA:
undetectable		 2bm9A-4l3fA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m75 U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM1
U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF01423
(LSM)
PF01423
(LSM) 		3 LYS B  50
ASP A 170
ASN B  21
 None
 1.01A 2bm9A-4m75B:
undetectable		 2bm9A-4m75B:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oua LATENT FORM OF PPO4
TYROSINASE

(Agaricus
bisporus) 		PF00264
(Tyrosinase) 		3 LYS B 208
ASP B 276
ASN B 193
 None
 0.91A 2bm9A-4ouaB:
undetectable		 2bm9A-4ouaB:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oua PROTEOLYTICALLY
ACTIVATED FORM OF
PPO4 TYROSINASE

(Agaricus
bisporus) 		PF00264
(Tyrosinase) 		3 LYS A 208
ASP A 276
ASN A 193
 None
 0.89A 2bm9A-4ouaA:
undetectable		 2bm9A-4ouaA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qax 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Staphylococcus
aureus) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		3 LYS A 425
ASP A 385
ASN A 382
 None
 0.84A 2bm9A-4qaxA:
6.1		 2bm9A-4qaxA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7z CELL DIVISION
CONTROL PROTEIN 21

(Pyrococcus
furiosus) 		PF00493
(MCM) 		3 LYS A 334
ASP A 820
ASN A 803
 ADP  A1001 ( 3.6A)
None
ADP  A1001 ( 4.7A)
 1.04A 2bm9A-4r7zA:
undetectable		 2bm9A-4r7zA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr2 SUBTILISIN-LIKE 1
SERINE PROTEASE

(Plasmodium
vivax) 		PF00082
(Peptidase_S8) 		3 LYS A 544
ASP A  79
ASN A  75
 None
 1.09A 2bm9A-4tr2A:
undetectable		 2bm9A-4tr2A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u10 POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Aggregatibacter
actinomycetemcomitans) 		PF01522
(Polysacc_deac_1) 		3 LYS A 259
ASP A  26
ASN A 262
 None
 1.18A 2bm9A-4u10A:
undetectable		 2bm9A-4u10A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yeh LECTIN

(Cicer arietinum) 		PF00045
(Hemopexin) 		3 LYS A 181
ASP A  38
ASN A  16
 None
 1.01A 2bm9A-4yehA:
undetectable		 2bm9A-4yehA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zcf RESTRICTION
ENDONUCLEASE
ECOP15I,
MODIFICATION SUBUNIT

(Escherichia
coli) 		PF01555
(N6_N4_Mtase) 		3 LYS A 266
ASP A 432
ASN A 261
 None
 1.12A 2bm9A-4zcfA:
2.4		 2bm9A-4zcfA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amq RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF04196
(Bunya_RdRp)
PF15518
(L_protein_N) 		3 LYS A 673
ASP A1187
ASN A1225
 None
 1.01A 2bm9A-5amqA:
undetectable		 2bm9A-5amqA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3d FLAGELLA SYNTHESIS
PROTEIN FLGN

(Salmonella
enterica) 		PF05130
(FlgN) 		3 LYS A  46
ASP A  90
ASN A  92
 None
 1.09A 2bm9A-5b3dA:
undetectable		 2bm9A-5b3dA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5but KTR SYSTEM POTASSIUM
UPTAKE PROTEIN A,KTR
SYSTEM POTASSIUM
UPTAKE PROTEIN A

(Bacillus
subtilis) 		PF02254
(TrkA_N) 		3 LYS A   7
ASP A 280
ASN A 282
 None
 1.17A 2bm9A-5butA:
7.5		 2bm9A-5butA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1b TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE

(Homo sapiens) 		PF00004
(AAA)
PF02359
(CDC48_N)
PF02933
(CDC48_2)
PF09336
(Vps4_C) 		3 LYS A 524
ASP A 627
ASN A 624
 AGS  A 902 (-3.0A)
None
AGS  A 902 (-2.7A)
 0.92A 2bm9A-5c1bA:
2.5		 2bm9A-5c1bA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dll AMINOPEPTIDASE N

(Francisella
tularensis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		3 LYS A 191
ASP A 169
ASN A 167
 None
 1.12A 2bm9A-5dllA:
undetectable		 2bm9A-5dllA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT ZETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		3 LYS z  40
ASP z 497
ASN z 494
 None
 0.99A 2bm9A-5gw5z:
undetectable		 2bm9A-5gw5z:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hkq CDII IMMUNITY
PROTEIN

(Escherichia
coli) 		no annotation 3 LYS I   3
ASP I  34
ASN I  30
 None
 1.09A 2bm9A-5hkqI:
undetectable		 2bm9A-5hkqI:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jh1 ALDOSE REDUCTASE,
AKR4C7

(Zea mays) 		PF00248
(Aldo_ket_red) 		3 LYS A 147
ASP A  99
ASN A  94
 None
 1.14A 2bm9A-5jh1A:
undetectable		 2bm9A-5jh1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jm0 ALPHA-MANNOSIDASE,AL
PHA-MANNOSIDASE,ALPH
A-MANNOSIDASE

(Saccharomyces
cerevisiae) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		3 LYS A 886
ASP A 590
ASN A 959
 None
 1.14A 2bm9A-5jm0A:
undetectable		 2bm9A-5jm0A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwa PROTEASOME-ASSOCIATE
D ATPASE

(Mycobacterium
tuberculosis) 		PF00004
(AAA)
PF16450
(Prot_ATP_ID_OB) 		3 LYS A 299
ASP A 419
ASN A 416
 ADP  A 701 (-3.0A)
None
ADP  A 701 ( 4.4A)
 1.02A 2bm9A-5kwaA:
3.3		 2bm9A-5kwaA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldn HEXON PROTEIN,HEXON
CAPSID

(Human
mastadenovirus
C) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 LYS A 685
ASP A 603
ASN A 498
 None
 1.08A 2bm9A-5ldnA:
undetectable		 2bm9A-5ldnA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mi0 RETICULOCYTE
BINDING-LIKE PROTEIN
5,RETICULOCYTE
BINDING PROTEIN 5

(Plasmodium
falciparum) 		no annotation 3 LYS A 429
ASP A 382
ASN A 377
 None
 0.88A 2bm9A-5mi0A:
undetectable		 2bm9A-5mi0A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtz RIBONUCLEASE Z

(Saccharomyces
cerevisiae) 		PF13691
(Lactamase_B_4) 		3 LYS A 490
ASP A 454
ASN A 457
 None
 1.10A 2bm9A-5mtzA:
undetectable		 2bm9A-5mtzA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nit GLUCOSE OXIDASE

(Aspergillus
niger) 		no annotation 3 LYS A 570
ASP A 120
ASN A 135
 None
 0.71A 2bm9A-5nitA:
3.0		 2bm9A-5nitA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tqr POLYCOMB PROTEIN EED

(Chaetomium
thermophilum) 		PF00400
(WD40) 		3 LYS A 121
ASP A  23
ASN A  95
 None
 0.93A 2bm9A-5tqrA:
undetectable		 2bm9A-5tqrA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb MINICHROMOSOME
MAINTENANCE PROTEIN
5

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		3 LYS 5 422
ASP 5 531
ASN 5 524
 None
 0.99A 2bm9A-5udb5:
undetectable		 2bm9A-5udb5:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wgx FLAVIN-DEPENDENT
HALOGENASE

(Malbranchea
aurantiaca) 		PF04820
(Trp_halogenase) 		3 LYS A 557
ASP A 571
ASN A 582
 None
 1.06A 2bm9A-5wgxA:
3.1		 2bm9A-5wgxA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wxu 11S GLOBULIN

(Wrightia
tinctoria) 		no annotation 3 LYS A 409
ASP A 306
ASN A 334
 None
 1.10A 2bm9A-5wxuA:
undetectable		 2bm9A-5wxuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6x MRNA CAPPING ENZYME
P5

(Rice dwarf
virus) 		no annotation 3 LYS C 231
ASP C 556
ASN C 494
 None
 1.01A 2bm9A-5x6xC:
6.7		 2bm9A-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwy A TYPE VI-A
CRISPR-CAS
RNA-GUIDED RNA
RIBONUCLEASE, CAS13A

(Leptotrichia
buccalis) 		no annotation 3 LYS A   2
ASP A 670
ASN A 668
 None
 0.89A 2bm9A-5xwyA:
undetectable		 2bm9A-5xwyA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y58 ATP-DEPENDENT DNA
HELICASE II SUBUNIT
1

(Saccharomyces
cerevisiae) 		no annotation 3 LYS A 138
ASP A  89
ASN A  86
 None
 1.17A 2bm9A-5y58A:
3.1		 2bm9A-5y58A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yz0 SERINE/THREONINE-PRO
TEIN KINASE ATR

(Homo sapiens) 		no annotation 3 LYS A2311
ASP A2484
ASN A2381
 None
 0.93A 2bm9A-5yz0A:
undetectable		 2bm9A-5yz0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yz0 SERINE/THREONINE-PRO
TEIN KINASE ATR

(Homo sapiens) 		no annotation 3 LYS A2329
ASP A2475
ASN A2496
 None
 1.08A 2bm9A-5yz0A:
undetectable		 2bm9A-5yz0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ek4 PAXB

(Photorhabdus
luminescens) 		no annotation 3 LYS A 174
ASP A 270
ASN A 265
 None
 1.07A 2bm9A-6ek4A:
undetectable		 2bm9A-6ek4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5o POLYMERASE ACIDIC
PROTEIN
RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT
POLYMERASE BASIC
PROTEIN 2

(Influenza B
virus;
Influenza B
virus;
Influenza B
virus) 		no annotation
no annotation
no annotation 		3 LYS A 568
ASP B 230
ASN C  44
 None
 1.06A 2bm9A-6f5oA:
undetectable		 2bm9A-6f5oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fqc BIFUNCTIONAL
ARGININE DEMETHYLASE
AND
LYSYL-HYDROXYLASE
JMJD6

(Homo sapiens) 		no annotation 3 LYS A 204
ASP A 189
ASN A 197
 OGA  A 506 (-2.9A)
MN  A 501 ( 2.6A)
OGA  A 506 (-3.6A)
 1.13A 2bm9A-6fqcA:
undetectable		 2bm9A-6fqcA:
undetectable