SIMILAR PATTERNS OF AMINO ACIDS FOR 2BJF_A_DXCA330_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ati | GLYCYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 5 | ARG A 260PHE A 230ALA A 362ILE A 229LEU A 45 | None | 1.12A | 2bjfA-1atiA:0.0 | 2bjfA-1atiA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cjx | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Pseudomonasfluorescens) |
PF00903(Glyoxalase)PF14696(Glyoxalase_5) | 5 | MET A 8ASN A 92ILE A 102ILE A 104LEU A 95 | None | 1.33A | 2bjfA-1cjxA:0.0 | 2bjfA-1cjxA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cul | TYPE II ADENYLYLCYCLASE (Rattusnorvegicus) |
PF00211(Guanylate_cyc) | 5 | MET B 972ALA B 946ILE B 919ILE B 918LEU B 926 | None | 1.32A | 2bjfA-1culB:0.0 | 2bjfA-1culB:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj3 | ADENYLOSUCCINATESYNTHETASE (Triticumaestivum) |
PF00709(Adenylsucc_synt) | 5 | CYH A 154PHE A 217ALA A 121ILE A 115ILE A 101 | None | 1.04A | 2bjfA-1dj3A:undetectable | 2bjfA-1dj3A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6z | CHITINASE B (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 5 | PHE A 154ASN A 166ILE A 141ILE A 183LEU A 165 | None | 1.21A | 2bjfA-1e6zA:0.0 | 2bjfA-1e6zA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fs5 | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Escherichiacoli) |
PF01182(Glucosamine_iso) | 5 | CYH A 239MET A 237ALA A 215THR A 251LEU A 247 | None | 1.32A | 2bjfA-1fs5A:undetectable | 2bjfA-1fs5A:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1la2 | MYO-INOSITOL-1-PHOSPHATE SYNTHASE (Saccharomycescerevisiae) |
PF01658(Inos-1-P_synth)PF07994(NAD_binding_5) | 5 | ASN A 258ILE A 223ILE A 185THR A 279LEU A 305 | None | 1.33A | 2bjfA-1la2A:0.0 | 2bjfA-1la2A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nr3 | DNA-BINDING PROTEINTFX (Methanothermobacterthermautotrophicus) |
PF14601(TFX_C) | 5 | ALA A 24ILE A 79ILE A 11THR A 84LEU A 88 | None | 1.14A | 2bjfA-1nr3A:undetectable | 2bjfA-1nr3A:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ql0 | NUCLEASE (Serratiamarcescens) |
PF01223(Endonuclease_NS) | 5 | MET A 241PHE A 188ALA A 186ILE A 218THR A 144 | None | 1.21A | 2bjfA-1ql0A:1.4 | 2bjfA-1ql0A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uaz | ARCHAERHODOPSIN-1 (Halorubrumchaoviator) |
PF01036(Bac_rhodopsin) | 5 | ALA A 132ILE A 196ILE A 197THR A 199LEU A 82 | None | 1.31A | 2bjfA-1uazA:undetectable | 2bjfA-1uazA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1w | STRUCTURALMAINTENANCE OFCHROMOSOME 1 (Saccharomycescerevisiae) |
PF02463(SMC_N) | 5 | TYR A 98PHE A 23ASN A 139ILE A1186ILE A 46 | None | 1.26A | 2bjfA-1w1wA:undetectable | 2bjfA-1w1wA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yj8 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE (Plasmodiumfalciparum) |
PF01210(NAD_Gly3P_dh_N)PF07479(NAD_Gly3P_dh_C) | 5 | PHE A 203ALA A 179ASN A 78ILE A 108LEU A 87 | None | 1.12A | 2bjfA-1yj8A:undetectable | 2bjfA-1yj8A:24.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zbs | HYPOTHETICAL PROTEINPG1100 (Porphyromonasgingivalis) |
PF01869(BcrAD_BadFG) | 5 | CYH A 70PHE A 26ILE A 53ILE A 16LEU A 82 | None | 1.28A | 2bjfA-1zbsA:undetectable | 2bjfA-1zbsA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2acv | TRITERPENEUDP-GLUCOSYLTRANSFERASE UGT71G1 (Medicagotruncatula) |
PF00201(UDPGT) | 5 | PHE A 45ALA A 30ILE A 13ILE A 110LEU A 40 | None | 1.33A | 2bjfA-2acvA:undetectable | 2bjfA-2acvA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 5 | PHE A 470ALA A 566ASN A 560ILE A 441ILE A 438 | None | 1.18A | 2bjfA-2c3oA:undetectable | 2bjfA-2c3oA:13.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ct8 | METHIONYL-TRNASYNTHETASE (Aquifexaeolicus) |
PF00133(tRNA-synt_1)PF08264(Anticodon_1)PF09334(tRNA-synt_1g) | 5 | ALA A 462ASN A 457ILE A 405ILE A 402THR A 455 | None | 1.24A | 2bjfA-2ct8A:undetectable | 2bjfA-2ct8A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fct | SYRINGOMYCINBIOSYNTHESIS ENZYME2 (Pseudomonassyringae) |
PF05721(PhyH) | 5 | PHE A 24ALA A 147ILE A 228ILE A 21LEU A 158 | None | 1.19A | 2bjfA-2fctA:undetectable | 2bjfA-2fctA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gup | ROK FAMILY PROTEIN (Streptococcuspneumoniae) |
PF00480(ROK) | 5 | CYH A 103ALA A 56ASN A 274ILE A 30LEU A 275 | NoneNoneSUC A 290 (-2.8A)NoneNone | 1.21A | 2bjfA-2gupA:undetectable | 2bjfA-2gupA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2igt | SAM DEPENDENTMETHYLTRANSFERASE (Agrobacteriumfabrum) |
PF10672(Methyltrans_SAM) | 5 | CYH A 237MET A 233PHE A 140ALA A 191ILE A 167 | NoneNoneSAM A1001 (-4.4A)SAM A1001 (-3.6A)ACY A1009 (-4.5A) | 1.31A | 2bjfA-2igtA:undetectable | 2bjfA-2igtA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ii1 | ACETAMIDASE (Bacillushalodurans) |
PF03069(FmdA_AmdA) | 5 | MET A 13ASN A 154ILE A 78ILE A 81LEU A 155 | None CA A 400 (-2.8A)NoneNoneNone | 1.11A | 2bjfA-2ii1A:undetectable | 2bjfA-2ii1A:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iv0 | ISOCITRATEDEHYDROGENASE (Archaeoglobusfulgidus) |
PF00180(Iso_dh) | 5 | MET A 205TYR A 360ALA A 122ILE A 114ILE A 88 | None | 1.06A | 2bjfA-2iv0A:undetectable | 2bjfA-2iv0A:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l10 | TALIN-1 (Mus musculus) |
PF08913(VBS) | 5 | PHE A1281ALA A1215ILE A1308ILE A1346LEU A1316 | None | 1.08A | 2bjfA-2l10A:undetectable | 2bjfA-2l10A:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oc6 | YDHG PROTEIN (Bacillussubtilis) |
PF08818(DUF1801) | 5 | TYR A 7PHE A 45ALA A 63ILE A 27THR A 20 | GOL A 128 (-3.6A)NoneNoneNoneNone | 1.06A | 2bjfA-2oc6A:undetectable | 2bjfA-2oc6A:17.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oqc | PENICILLIN V ACYLASE (Bacillussubtilis) |
PF02275(CBAH) | 5 | CYH A 1ARG A 17MET A 19ALA A 68LEU A 142 | None | 0.34A | 2bjfA-2oqcA:43.3 | 2bjfA-2oqcA:39.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q07 | UNCHARACTERIZEDPROTEIN AF0587 (Archaeoglobusfulgidus) |
PF01472(PUA) | 5 | PHE A 499ALA A 452ASN A 458ILE A 520THR A 461 | None | 1.15A | 2bjfA-2q07A:undetectable | 2bjfA-2q07A:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qc5 | STREPTOGRAMIN BLACTONASE (Staphylococcuscohnii) |
no annotation | 5 | PHE A 145ASN A 75ILE A 63ILE A 112THR A 73 | PHE A 145 ( 1.3A)ASN A 75 ( 0.6A)ILE A 63 ( 0.4A)ILE A 112 ( 0.7A)THR A 73 ( 0.8A) | 1.30A | 2bjfA-2qc5A:undetectable | 2bjfA-2qc5A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qm1 | GLUCOKINASE (Enterococcusfaecalis) |
PF00480(ROK) | 5 | ALA A 110ASN A 113ILE A 47ILE A 43THR A 72 | None | 1.17A | 2bjfA-2qm1A:undetectable | 2bjfA-2qm1A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qm1 | GLUCOKINASE (Enterococcusfaecalis) |
PF00480(ROK) | 5 | ALA A 312ASN A 113ILE A 15ILE A 43THR A 72 | None | 1.31A | 2bjfA-2qm1A:undetectable | 2bjfA-2qm1A:22.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2quy | PENICILLIN ACYLASE (Lysinibacillussphaericus) |
PF02275(CBAH) | 5 | CYH A 1ARG A 17MET A 19ILE A 62ILE A 134 | None | 0.92A | 2bjfA-2quyA:42.9 | 2bjfA-2quyA:36.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rg2 | CHOLOYLGLYCINEHYDROLASE (Clostridiumperfringens) |
PF02275(CBAH) | 7 | MET A 20PHE A 26ALA A 68ASN A 82ILE A 137THR A 140LEU A 142 | EDO A 333 (-3.8A)EDO A 334 (-4.2A)EDO A 333 ( 3.7A)GOL A 336 (-3.7A)NoneNoneEDO A 333 ( 4.5A) | 1.03A | 2bjfA-2rg2A:53.1 | 2bjfA-2rg2A:99.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rg2 | CHOLOYLGLYCINEHYDROLASE (Clostridiumperfringens) |
PF02275(CBAH) | 7 | MET A 20TYR A 24ASN A 82ILE A 133ILE A 137THR A 140LEU A 142 | EDO A 333 (-3.8A)NoneGOL A 336 (-3.7A)NoneNoneNoneEDO A 333 ( 4.5A) | 1.13A | 2bjfA-2rg2A:53.1 | 2bjfA-2rg2A:99.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rg2 | CHOLOYLGLYCINEHYDROLASE (Clostridiumperfringens) |
PF02275(CBAH) | 8 | MET A 20TYR A 24PHE A 26ALA A 68ASN A 82ILE A 133THR A 140LEU A 142 | EDO A 333 (-3.8A)NoneEDO A 334 (-4.2A)EDO A 333 ( 3.7A)GOL A 336 (-3.7A)NoneNoneEDO A 333 ( 4.5A) | 0.67A | 2bjfA-2rg2A:53.1 | 2bjfA-2rg2A:99.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rg2 | CHOLOYLGLYCINEHYDROLASE (Clostridiumperfringens) |
PF02275(CBAH) | 7 | TYR A 24PHE A 61ASN A 82ILE A 133ILE A 137THR A 140LEU A 142 | NoneNoneGOL A 336 (-3.7A)NoneNoneNoneEDO A 333 ( 4.5A) | 1.32A | 2bjfA-2rg2A:53.1 | 2bjfA-2rg2A:99.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpq | ACETYL-COACARBOXYLASE (Staphylococcusaureus) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | PHE A 410ALA A 402ILE A 419ILE A 339LEU A 426 | None | 1.25A | 2bjfA-2vpqA:undetectable | 2bjfA-2vpqA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vwb | PUTATIVEO-SIALOGLYCOPROTEINENDOPEPTIDASE (Methanocaldococcusjannaschii) |
PF00814(Peptidase_M22)PF01163(RIO1) | 5 | ARG A 332ALA A 240ILE A 197THR A 235LEU A 124 | None | 1.32A | 2bjfA-2vwbA:undetectable | 2bjfA-2vwbA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yha | POST-TRANSCRIPTIONALGENE SILENCINGPROTEIN QDE-2 (Neurosporacrassa) |
PF02171(Piwi) | 5 | MET A 869PHE A 743ILE A 779THR A 658LEU A 652 | None | 1.29A | 2bjfA-2yhaA:undetectable | 2bjfA-2yhaA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zqq | METHYLGLUTACONYL-COAHYDRATASE (Homo sapiens) |
PF00378(ECH_1) | 5 | ARG A 146PHE A 137ALA A 141ILE A 94ILE A 129 | None | 1.27A | 2bjfA-2zqqA:undetectable | 2bjfA-2zqqA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b96 | VERY LONG-CHAINSPECIFIC ACYL-COADEHYDROGENASE (Homo sapiens) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | PHE A 219PHE A 174ALA A 216ILE A 144LEU A 165 | NoneMYA A 1 (-4.8A)NoneMYA A 1 (-4.9A)None | 1.16A | 2bjfA-3b96A:undetectable | 2bjfA-3b96A:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b96 | VERY LONG-CHAINSPECIFIC ACYL-COADEHYDROGENASE (Homo sapiens) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | PHE A 219PHE A 174ILE A 144ILE A 296LEU A 165 | NoneMYA A 1 (-4.8A)MYA A 1 (-4.9A)NoneNone | 1.10A | 2bjfA-3b96A:undetectable | 2bjfA-3b96A:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bjc | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 5 | MET A 578PHE A 619PHE A 564ILE A 774ILE A 778 | None | 1.32A | 2bjfA-3bjcA:undetectable | 2bjfA-3bjcA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3blw | ISOCITRATEDEHYDROGENASE [NAD]SUBUNIT 1 (Saccharomycescerevisiae) |
PF00180(Iso_dh) | 5 | ARG A 274PHE A 230ALA A 108ILE A 214THR A 235 | FLC A1001 (-3.4A)NoneNoneNoneNone | 1.13A | 2bjfA-3blwA:undetectable | 2bjfA-3blwA:25.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cuc | PROTEIN OF UNKNOWNFUNCTION WITH A FICDOMAIN (Bacteroidesthetaiotaomicron) |
PF02661(Fic) | 5 | ALA A 182ASN A 207ILE A 6ILE A 266LEU A 210 | None | 1.29A | 2bjfA-3cucA:undetectable | 2bjfA-3cucA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ele | AMINO TRANSFERASE ([Eubacterium]rectale) |
PF00155(Aminotran_1_2) | 5 | PHE A 133ILE A 214ILE A 177THR A 128LEU A 147 | PLP A 500 (-4.0A)NoneNoneNoneNone | 1.19A | 2bjfA-3eleA:undetectable | 2bjfA-3eleA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euw | MYO-INOSITOLDEHYDROGENASE (Corynebacteriumglutamicum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | ALA A 18ASN A 24ILE A 67ILE A 88LEU A 288 | None | 1.26A | 2bjfA-3euwA:undetectable | 2bjfA-3euwA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7n | NUCLEOPORIN NUP120 (Saccharomycescerevisiae) |
PF11715(Nup160) | 5 | TYR A 313PHE A 315PHE A 373THR A 289LEU A 291 | None | 1.29A | 2bjfA-3h7nA:undetectable | 2bjfA-3h7nA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ij6 | UNCHARACTERIZEDMETAL-DEPENDENTHYDROLASE (Lactobacillusacidophilus) |
PF04909(Amidohydro_2) | 5 | ALA A 248ILE A 276ILE A 275THR A 242LEU A 283 | None | 1.32A | 2bjfA-3ij6A:undetectable | 2bjfA-3ij6A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kw0 | CYSTEINE PEPTIDASE (Bacillus cereus) |
PF05708(Peptidase_C92) | 5 | PHE A 27ALA A 183ASN A 7ILE A 96ILE A 194 | None | 1.25A | 2bjfA-3kw0A:undetectable | 2bjfA-3kw0A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpn | TRANSPORTER (Aquifexaeolicus) |
PF00209(SNF) | 5 | TYR A 47PHE A 51ALA A 283ASN A 27THR A 254 | NoneNoneNone NA A 752 ( 2.8A) NA A 752 ( 3.3A) | 1.26A | 2bjfA-3mpnA:undetectable | 2bjfA-3mpnA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2n | ANTHRAX TOXINRECEPTOR 1 (Homo sapiens) |
no annotation | 5 | PHE F 82ALA F 70ILE F 146ILE F 145LEU F 78 | None | 1.19A | 2bjfA-3n2nF:undetectable | 2bjfA-3n2nF:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nlc | UNCHARACTERIZEDPROTEIN VP0956 (Vibrioparahaemolyticus) |
no annotation | 5 | ARG A 489PHE A 105ALA A 504ILE A 125ILE A 220 | None | 1.26A | 2bjfA-3nlcA:undetectable | 2bjfA-3nlcA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opz | HEAVY CHAIN OF THEFAB FRAGMENT OFIMMUNOGLOBULIN G (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | TYR H 181ALA H 207ILE H 93THR H 116LEU H 11 | None | 1.25A | 2bjfA-3opzH:undetectable | 2bjfA-3opzH:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3owa | ACYL-COADEHYDROGENASE (Bacillusanthracis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | PHE A 193ALA A 190ILE A 118ILE A 261LEU A 139 | None | 1.31A | 2bjfA-3owaA:undetectable | 2bjfA-3owaA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qty | PHOSPHORIBOSYLAMINOIMIDAZOLE (AIR)SYNTHETASE (Francisellatularensis) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | MET A 320PHE A 182ALA A 312ILE A 261ILE A 252 | None | 1.25A | 2bjfA-3qtyA:undetectable | 2bjfA-3qtyA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqz | PUTATIVEHYDROXYMETHYLGLUTARYL-COA SYNTHASE (Streptococcusmutans) |
PF00195(Chal_sti_synt_N)PF08540(HMG_CoA_synt_C) | 5 | PHE A 10ALA A 56ILE A 158ILE A 277LEU A 76 | GOL A 392 (-4.9A)NoneNoneNoneNone | 1.19A | 2bjfA-3sqzA:undetectable | 2bjfA-3sqzA:23.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sy6 | FIMBRIAL PROTEINBF1861 (Bacteroidesfragilis) |
PF13149(Mfa_like_1) | 5 | PHE A 184ALA A 289ILE A 247ILE A 182THR A 164 | None | 1.30A | 2bjfA-3sy6A:undetectable | 2bjfA-3sy6A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usw | FLAGELLAR MOTORSWITCH PROTEIN (Helicobacterpylori) |
PF01706(FliG_C)PF14841(FliG_M) | 5 | ARG A 293PHE A 286ALA A 294ILE A 259ILE A 262 | None | 1.29A | 2bjfA-3uswA:undetectable | 2bjfA-3uswA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wp5 | CDBFV (Neocallimastixpatriciarum) |
PF00457(Glyco_hydro_11) | 5 | MET A 78PHE A 66ALA A 197ILE A 153THR A 103 | None | 1.34A | 2bjfA-3wp5A:undetectable | 2bjfA-3wp5A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8s | ADP-DEPENDENTGLUCOKINASE (Thermococcuslitoralis) |
PF04587(ADP_PFK_GK) | 5 | ARG A 348PHE A 20ALA A 457ILE A 394ILE A 391 | None | 1.29A | 2bjfA-4b8sA:undetectable | 2bjfA-4b8sA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0g | SERINE/THREONINE-PROTEIN KINASE ROCO4 (Dictyosteliumdiscoideum) |
PF07714(Pkinase_Tyr) | 5 | PHE A1219ALA A1199ASN A1194ILE A1140ILE A1136 | None | 1.17A | 2bjfA-4f0gA:undetectable | 2bjfA-4f0gA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fo7 | METHIONINEAMINOPEPTIDASE (Pseudomonasaeruginosa) |
PF00557(Peptidase_M24) | 5 | PHE A 112ASN A 83ILE A 32ILE A 28THR A 38 | None | 1.30A | 2bjfA-4fo7A:undetectable | 2bjfA-4fo7A:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ikn | AP-3 COMPLEX SUBUNITMU-1 (Rattusnorvegicus) |
PF00928(Adap_comp_sub) | 5 | MET A 314PHE A 282ASN A 372THR A 418LEU A 373 | MET A 314 ( 0.0A)PHE A 282 ( 1.3A)ASN A 372 ( 0.6A)THR A 418 ( 0.8A)LEU A 373 ( 0.5A) | 1.19A | 2bjfA-4iknA:undetectable | 2bjfA-4iknA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mif | PYRANOSE 2-OXIDASE (Phanerochaetechrysosporium) |
PF05199(GMC_oxred_C) | 5 | CYH A 560PHE A 28ALA A 608ILE A 203ILE A 204 | None | 1.26A | 2bjfA-4mifA:undetectable | 2bjfA-4mifA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj6 | LEUCYL-CYSTINYLAMINOPEPTIDASE (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | TYR A 177PHE A 303ALA A 299ILE A 243ILE A 245 | None | 1.15A | 2bjfA-4pj6A:undetectable | 2bjfA-4pj6A:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3e | PEPTIDYL-PROLYLCIS-TRANS ISOMERASECWC27 HOMOLOG (Homo sapiens) |
PF00160(Pro_isomerase) | 5 | MET A 101TYR A 49ALA A 36ILE A 174LEU A 28 | None | 1.20A | 2bjfA-4r3eA:undetectable | 2bjfA-4r3eA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4sli | INTRAMOLECULARTRANS-SIALIDASE (Macrobdelladecora) |
PF02973(Sialidase)PF13088(BNR_2) | 5 | PHE A 248ALA A 245ILE A 94ILE A 252THR A 234 | None | 1.28A | 2bjfA-4sliA:undetectable | 2bjfA-4sliA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wa8 | FLAP ENDONUCLEASE 1 (Methanopyruskandleri) |
PF00752(XPG_N)PF00867(XPG_I) | 5 | ALA A 29ILE A 185ILE A 73THR A 65LEU A 61 | None | 1.25A | 2bjfA-4wa8A:undetectable | 2bjfA-4wa8A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xqe | HOMOSPERMIDINESYNTHASE (Blastochlorisviridis) |
PF03435(Sacchrp_dh_NADP)PF16653(Sacchrp_dh_C) | 5 | PHE A 36ALA A 81ILE A 10ILE A 30LEU A 79 | None | 1.19A | 2bjfA-4xqeA:undetectable | 2bjfA-4xqeA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y85 | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE 8 (Homo sapiens) |
PF00069(Pkinase) | 5 | PHE A 271ALA A 196ASN A 111ILE A 181ILE A 190 | None | 1.28A | 2bjfA-4y85A:undetectable | 2bjfA-4y85A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y85 | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE 8 (Homo sapiens) |
PF00069(Pkinase) | 5 | PHE A 271ALA A 196ASN A 111ILE A 190LEU A 110 | None | 1.25A | 2bjfA-4y85A:undetectable | 2bjfA-4y85A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yt9 | PEPTIDYLARGININEDEIMINASE (Porphyromonasgingivalis) |
PF04371(PAD_porph) | 5 | TYR A 189ASN A 247ILE A 380ILE A 437LEU A 370 | NoneGOL A 506 ( 4.9A)NoneNoneNone | 1.22A | 2bjfA-4yt9A:undetectable | 2bjfA-4yt9A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z38 | MLNA (Bacillusvelezensis) |
no annotation | 6 | MET A 752PHE A 566ALA A 342ILE A 550ILE A 510LEU A 344 | None | 1.39A | 2bjfA-4z38A:undetectable | 2bjfA-4z38A:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a7m | BETA-XYLOSIDASE (Trichodermareesei) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 5 | TYR A 147PHE A 112ALA A 153ILE A 130ILE A 133 | None | 1.30A | 2bjfA-5a7mA:undetectable | 2bjfA-5a7mA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5adv | ENTEROCHELIN UPTAKEPERIPLASMIC BINDINGPROTEIN (Campylobacterjejuni) |
PF01497(Peripla_BP_2) | 5 | PHE A 245ALA A 199ASN A 221ILE A 209ILE A 215 | None | 1.07A | 2bjfA-5advA:undetectable | 2bjfA-5advA:24.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cef | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Cryptococcusneoformans) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | TYR A 281ALA A 293ILE A 124ILE A 221LEU A 345 | None | 1.34A | 2bjfA-5cefA:undetectable | 2bjfA-5cefA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | PHE A 410ALA A 223ILE A 198ILE A 418LEU A 215 | NoneEDO A1007 ( 3.7A)NoneNoneNone | 1.33A | 2bjfA-5chcA:undetectable | 2bjfA-5chcA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4r | KETOL-ACIDREDUCTOISOMERASE (Ignisphaeraaggregans) |
PF01450(IlvC)PF07991(IlvN) | 5 | MET A 472TYR A 372PHE A 373ILE A 198LEU A 381 | None | 1.29A | 2bjfA-5e4rA:undetectable | 2bjfA-5e4rA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e68 | S-RIBOSYLHOMOCYSTEINE LYASE (Salmonellaenterica) |
PF02664(LuxS) | 5 | MET A 14ALA A 16ASN A 44ILE A 142ILE A 53 | NoneNoneNoneNonePAV A 202 ( 4.2A) | 1.29A | 2bjfA-5e68A:undetectable | 2bjfA-5e68A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gkq | ALYGC MUTANT - R241A (Paraglaciecolachathamensis) |
PF14592(Chondroitinas_B) | 5 | PHE A 207ASN A 315ILE A 216ILE A 217LEU A 278 | None | 1.18A | 2bjfA-5gkqA:undetectable | 2bjfA-5gkqA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 5 | PHE a 139PHE a 436ALA a 428ILE a 448LEU a 455 | None | 1.02A | 2bjfA-5gw5a:undetectable | 2bjfA-5gw5a:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h42 | UNCHARACTERIZEDPROTEIN (Lachnoclostridiumphytofermentans) |
PF17167(Glyco_hydro_36) | 5 | PHE A1107ALA A1100ASN A1073ILE A1090ILE A1067 | None | 1.12A | 2bjfA-5h42A:undetectable | 2bjfA-5h42A:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5j | FERREDOXIN--NADPREDUCTASE (Zea mays) |
PF00175(NAD_binding_1) | 5 | MET A 158PHE A 181PHE A 205ILE A 255ILE A 262 | None | 1.32A | 2bjfA-5h5jA:undetectable | 2bjfA-5h5jA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ik2 | ATP SYNTHASE SUBUNITALPHAATP SYNTHASE GAMMACHAIN (Caldalkalibacillusthermarum;Caldalkalibacillusthermarum) |
PF00006(ATP-synt_ab)PF00306(ATP-synt_ab_C)PF02874(ATP-synt_ab_N)PF00231(ATP-synt) | 5 | ARG G 5PHE A 343ALA A 323ILE A 168ILE A 335 | None | 1.17A | 2bjfA-5ik2G:undetectable | 2bjfA-5ik2G:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j44 | SERINE PROTEASE SEPAAUTOTRANSPORTER (Shigellaflexneri) |
PF02395(Peptidase_S6) | 5 | PHE A 216ALA A 122ILE A 127THR A 244LEU A 249 | None | 1.32A | 2bjfA-5j44A:undetectable | 2bjfA-5j44A:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5je8 | 3-HYDROXYISOBUTYRATEDEHYDROGENASE (Bacillus cereus) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 5 | PHE A 91PHE A 62ALA A 55ILE A 4ILE A 150 | None | 1.07A | 2bjfA-5je8A:undetectable | 2bjfA-5je8A:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lgg | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT1,ANAPHASE-PROMOTINGCOMPLEX SUBUNIT1,ANAPHASE-PROMOTINGCOMPLEX SUBUNIT1,ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 5 | CYH A 152MET A 161ALA A 171ILE A 403LEU A 173 | None | 1.28A | 2bjfA-5lggA:undetectable | 2bjfA-5lggA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 6 | PHE A3868PHE A3864ALA A3872ILE A3811ILE A3890LEU A3818 | None | 1.44A | 2bjfA-5nugA:undetectable | 2bjfA-5nugA:5.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5od2 | BIFUNCTIONALADP-SPECIFICGLUCOKINASE/PHOSPHOFRUCTOKINASE (Methanocaldococcusjannaschii) |
no annotation | 5 | MET A 105PHE A 20ILE A 211THR A 128LEU A 131 | None | 1.32A | 2bjfA-5od2A:undetectable | 2bjfA-5od2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opt | 40S RIBOSOMALPROTEIN S10,PUTATIVE (Trypanosomacruzi) |
no annotation | 5 | PHE n 18PHE n 17ASN n 96ILE n 23ILE n 62 | None | 1.24A | 2bjfA-5optn:undetectable | 2bjfA-5optn:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tte | E3 UBIQUITIN-PROTEINLIGASE ARIH1 (Homo sapiens) |
PF01485(IBR) | 5 | ARG B 247TYR B 258ILE B 130ILE B 133LEU B 201 | None | 1.26A | 2bjfA-5tteB:undetectable | 2bjfA-5tteB:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9z | PHOSPHOGLYCEROLTRANSFERASE (Streptococcuspyogenes) |
no annotation | 5 | MET A 561PHE A 535ASN A 595ILE A 645LEU A 596 | None | 1.16A | 2bjfA-5u9zA:undetectable | 2bjfA-5u9zA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udb | MINICHROMOSOMEMAINTENANCE PROTEIN5 (Saccharomycescerevisiae) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 5 | MET 5 497PHE 5 550PHE 5 554ALA 5 521ILE 5 384 | None | 1.26A | 2bjfA-5udb5:undetectable | 2bjfA-5udb5:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5upr | TRIOSEPHOSPHATEISOMERASE (Toxoplasmagondii) |
PF00121(TIM) | 5 | PHE A 121ALA A 327ILE A 331ILE A 245LEU A 316 | None | 1.02A | 2bjfA-5uprA:undetectable | 2bjfA-5uprA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbg | CYTOCHROME P450 2B6 (Homo sapiens) |
no annotation | 5 | PHE A 449PHE A 450ILE A 353ILE A 356THR A 303 | NoneNoneNoneNoneHEM A 501 ( 4.6A) | 1.24A | 2bjfA-5wbgA:undetectable | 2bjfA-5wbgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wlh | LBACAS13A H328A(C2C2) (LachnospiraceaebacteriumNK4A179) |
no annotation | 5 | TYR A1263PHE A1259PHE A1365ALA A1112ILE A1327 | None | 1.11A | 2bjfA-5wlhA:undetectable | 2bjfA-5wlhA:12.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xip | PROLYL-TRNASYNTHETASE, PUTATIVE (Eimeria tenella) |
no annotation | 5 | MET A 636PHE A 587ILE A 543ILE A 545THR A 611 | None | 1.24A | 2bjfA-5xipA:undetectable | 2bjfA-5xipA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyn | PLATINUM SENSITIVITYPROTEIN 3 (Saccharomycescerevisiae) |
no annotation | 5 | TYR A 215PHE A 161ILE A 133ILE A 73THR A 177 | None | 1.29A | 2bjfA-5xynA:undetectable | 2bjfA-5xynA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y58 | ATP-DEPENDENT DNAHELICASE II SUBUNIT1 (Saccharomycescerevisiae) |
no annotation | 5 | PHE A 171ASN A 112ILE A 58ILE A 257LEU A 115 | None | 1.24A | 2bjfA-5y58A:undetectable | 2bjfA-5y58A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bka | NITRONATEMONOOXYGENASE (Cyberlindneramrakii) |
no annotation | 5 | PHE A 176ALA A 238ILE A 220ILE A 224LEU A 250 | NoneFMN A 401 ( 4.0A)NoneNoneNone | 1.08A | 2bjfA-6bkaA:undetectable | 2bjfA-6bkaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6em0 | 2-HYDROXYBIPHENYL-3-MONOOXYGENASE (Pseudomonasnitroreducens) |
no annotation | 5 | PHE A 461ASN A 327ILE A 426ILE A 425LEU A 324 | None | 1.33A | 2bjfA-6em0A:undetectable | 2bjfA-6em0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fb3 | TENEURIN-2 (Gallus gallus) |
no annotation | 5 | TYR A1317PHE A1280ALA A1588ILE A1299LEU A1265 | None | 1.04A | 2bjfA-6fb3A:undetectable | 2bjfA-6fb3A:undetectable |