SIMILAR PATTERNS OF AMINO ACIDS FOR 2BFP_B_H4BB1290
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a88 | CHLOROPEROXIDASE L (Streptomyceslividans) |
PF00561(Abhydrolase_1) | 4 | SER A 46PHE A 44LEU A 265LEU A 258 | None | 0.92A | 2bfpB-1a88A:5.2 | 2bfpB-1a88A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ihm | CAPSID PROTEIN (Norwalk virus) |
PF00915(Calici_coat)PF08435(Calici_coat_C) | 4 | SER A1244PHE A1421LEU A1481LEU A1233 | None | 0.98A | 2bfpB-1ihmA:undetectable | 2bfpB-1ihmA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j2b | ARCHAEOSINETRNA-GUANINETRANSGLYCOSYLASE (Pyrococcushorikoshii) |
PF01472(PUA)PF01702(TGT)PF14809(TGT_C1)PF14810(TGT_C2) | 4 | SER A 96PHE A 128LEU A 184LEU A 146 | G D 915 ( 4.2A)NoneNoneNone | 0.94A | 2bfpB-1j2bA:undetectable | 2bfpB-1j2bA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j85 | YIBK (Haemophilusinfluenzae) |
PF00588(SpoU_methylase) | 4 | PHE A 54LEU A 44LEU A 31LEU A 29 | None | 0.94A | 2bfpB-1j85A:2.5 | 2bfpB-1j85A:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m2v | PROTEIN TRANSPORTPROTEIN SEC24 (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | SER B 316PHE B 422LEU B 309LEU B 499LEU B 512 | None | 1.33A | 2bfpB-1m2vB:2.3 | 2bfpB-1m2vB:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mw5 | HYPOTHETICAL PROTEINHI1480 (Haemophilusinfluenzae) |
no annotation | 5 | SER A 130PHE A 131LEU A 73LEU A 92LEU A 96 | None | 1.37A | 2bfpB-1mw5A:undetectable | 2bfpB-1mw5A:20.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mxf | PTERIDINE REDUCTASE2 (Trypanosomacruzi) |
PF13561(adh_short_C2) | 5 | ARG A 22SER A 103ASP A 169LEU A 176TYR A 182 | NDP A1277 ( 3.9A)MTX A1278 ( 2.7A)NDP A1277 (-3.9A)MTX A1278 (-4.5A)MTX A1278 ( 4.7A) | 0.38A | 2bfpB-1mxfA:40.2 | 2bfpB-1mxfA:48.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mxf | PTERIDINE REDUCTASE2 (Trypanosomacruzi) |
PF13561(adh_short_C2) | 5 | ARG A 22SER A 103ASP A 169TYR A 182LEU A 214 | NDP A1277 ( 3.9A)MTX A1278 ( 2.7A)NDP A1277 (-3.9A)MTX A1278 ( 4.7A)MTX A1278 (-4.4A) | 0.68A | 2bfpB-1mxfA:40.2 | 2bfpB-1mxfA:48.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mxf | PTERIDINE REDUCTASE2 (Trypanosomacruzi) |
PF13561(adh_short_C2) | 5 | ARG A 22SER A 103ASP A 169TYR A 182LEU A 217 | NDP A1277 ( 3.9A)MTX A1278 ( 2.7A)NDP A1277 (-3.9A)MTX A1278 ( 4.7A)None | 0.68A | 2bfpB-1mxfA:40.2 | 2bfpB-1mxfA:48.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mxf | PTERIDINE REDUCTASE2 (Trypanosomacruzi) |
PF13561(adh_short_C2) | 4 | SER A 103LEU A 176TYR A 182LEU A 214 | MTX A1278 ( 2.7A)MTX A1278 (-4.5A)MTX A1278 ( 4.7A)MTX A1278 (-4.4A) | 0.93A | 2bfpB-1mxfA:40.2 | 2bfpB-1mxfA:48.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o1y | CONSERVEDHYPOTHETICAL PROTEINTM1158 (Thermotogamaritima) |
PF00117(GATase) | 4 | PHE A 125LEU A 170LEU A 217LEU A 221 | None | 0.97A | 2bfpB-1o1yA:3.7 | 2bfpB-1o1yA:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogq | POLYGALACTURONASEINHIBITING PROTEIN (Phaseolusvulgaris) |
PF08263(LRRNT_2) | 4 | PHE A 217LEU A 251LEU A 260LEU A 264 | None | 0.95A | 2bfpB-1ogqA:undetectable | 2bfpB-1ogqA:23.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p33 | PTERIDINE REDUCTASE1 (Leishmaniatarentolae) |
PF13561(adh_short_C2) | 7 | ARG A 17SER A 111PHE A 113ASP A 181LEU A 188TYR A 194LEU A 226 | NDP A 300 ( 3.7A)MTX A 351 ( 2.8A)MTX A 351 (-3.5A)NDP A 300 ( 3.7A)MTX A 351 (-4.5A)MTX A 351 ( 4.4A)MTX A 351 ( 4.4A) | 0.37A | 2bfpB-1p33A:44.4 | 2bfpB-1p33A:80.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p33 | PTERIDINE REDUCTASE1 (Leishmaniatarentolae) |
PF13561(adh_short_C2) | 6 | ARG A 17SER A 111PHE A 113ASP A 181TYR A 194LEU A 229 | NDP A 300 ( 3.7A)MTX A 351 ( 2.8A)MTX A 351 (-3.5A)NDP A 300 ( 3.7A)MTX A 351 ( 4.4A)MTX A 351 (-4.9A) | 0.60A | 2bfpB-1p33A:44.4 | 2bfpB-1p33A:80.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p33 | PTERIDINE REDUCTASE1 (Leishmaniatarentolae) |
PF13561(adh_short_C2) | 5 | SER A 111PHE A 113LEU A 188TYR A 194LEU A 226 | MTX A 351 ( 2.8A)MTX A 351 (-3.5A)MTX A 351 (-4.5A)MTX A 351 ( 4.4A)MTX A 351 ( 4.4A) | 0.77A | 2bfpB-1p33A:44.4 | 2bfpB-1p33A:80.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd1 | PROTEIN TRANSPORTPROTEIN SEC24 (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | SER A 316PHE A 422LEU A 309LEU A 499LEU A 512 | None | 1.28A | 2bfpB-1pd1A:2.2 | 2bfpB-1pd1A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pf5 | HYPOTHETICAL PROTEINYJGH (Escherichiacoli) |
PF01042(Ribonuc_L-PSP) | 5 | SER A 100PHE A 99ASP A 72LEU A 64LEU A 60 | None | 1.41A | 2bfpB-1pf5A:undetectable | 2bfpB-1pf5A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pvh | LEUKEMIA INHIBITORYFACTOR (Homo sapiens) |
PF01291(LIF_OSM) | 4 | PHE B 67LEU B 90TYR B 89LEU B 166 | None | 1.00A | 2bfpB-1pvhB:undetectable | 2bfpB-1pvhB:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q8k | EUKARYOTICTRANSLATIONINITIATION FACTOR 2SUBUNIT 1 (Homo sapiens) |
PF00575(S1)PF07541(EIF_2_alpha) | 4 | PHE A 152LEU A 111LEU A 167LEU A 165 | None | 0.97A | 2bfpB-1q8kA:undetectable | 2bfpB-1q8kA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qpo | QUINOLINATE ACIDPHOSPHORIBOSYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 4 | ASP A 80LEU A 3LEU A 114LEU A 110 | None | 0.93A | 2bfpB-1qpoA:undetectable | 2bfpB-1qpoA:26.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s5t | DIHYDRODIPICOLINATESYNTHASE (Escherichiacoli) |
PF00701(DHDPS) | 4 | SER A 34LEU A 259TYR A 30LEU A 239 | None | 0.96A | 2bfpB-1s5tA:undetectable | 2bfpB-1s5tA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sfn | CONSERVEDHYPOTHETICAL PROTEIN (Deinococcusradiodurans) |
PF05899(Cupin_3) | 4 | PHE A1172LEU A1178LEU A1236LEU A1190 | None | 0.99A | 2bfpB-1sfnA:undetectable | 2bfpB-1sfnA:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxj | ACTIVATOR 1 40 KDASUBUNITACTIVATOR 1 41 KDASUBUNIT (Saccharomycescerevisiae) |
PF00004(AAA)PF08542(Rep_fac_C) | 4 | SER D 323LEU C 299LEU C 248LEU C 252 | None | 0.96A | 2bfpB-1sxjD:undetectable | 2bfpB-1sxjD:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tfd | TRANSFERRIN (Oryctolaguscuniculus) |
PF00405(Transferrin) | 4 | SER A 189PHE A 186LEU A 62LEU A 66 | None | 1.00A | 2bfpB-1tfdA:undetectable | 2bfpB-1tfdA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w27 | PHENYLALANINEAMMONIA-LYASE 1 (Petroselinumcrispum) |
PF00221(Lyase_aromatic) | 4 | ARG A 546PHE A 622LEU A 593LEU A 630 | None | 0.96A | 2bfpB-1w27A:undetectable | 2bfpB-1w27A:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6v | EMP46P (Saccharomycescerevisiae) |
PF03388(Lectin_leg-like) | 5 | SER A 196PHE A 192LEU A 132LEU A 175LEU A 165 | None | 1.49A | 2bfpB-2a6vA:undetectable | 2bfpB-2a6vA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ani | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASEBETA SUBUNIT (Chlamydiatrachomatis) |
PF00268(Ribonuc_red_sm) | 4 | PHE A 233LEU A 113TYR A 112LEU A 185 | None | 0.97A | 2bfpB-2aniA:undetectable | 2bfpB-2aniA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b2c | SPERMIDINE SYNTHASE (Caenorhabditiselegans) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | PHE A 238LEU A 235LEU A 218LEU A 208 | None | 0.98A | 2bfpB-2b2cA:4.8 | 2bfpB-2b2cA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c1z | UDP-GLUCOSEFLAVONOID 3-OGLYCOSYLTRANSFERASE (Vitis vinifera) |
PF00201(UDPGT) | 4 | SER A 439PHE A 222LEU A 425LEU A 356 | None | 0.94A | 2bfpB-2c1zA:5.1 | 2bfpB-2c1zA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c7i | PUTATIVE LIPOATEPROTEIN LIGASE (Thermoplasmaacidophilum) |
PF03099(BPL_LplA_LipB) | 4 | SER A 17LEU A 86LEU A 36LEU A 5 | None | 0.89A | 2bfpB-2c7iA:undetectable | 2bfpB-2c7iA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cv6 | SEED STORAGE PROTEIN (Vigna radiata) |
PF00190(Cupin_1) | 4 | SER A 146PHE A 144LEU A 35LEU A 116 | None | 0.97A | 2bfpB-2cv6A:undetectable | 2bfpB-2cv6A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cw7 | ENDONUCLEASEPI-PKOII (Thermococcuskodakarensis) |
PF14528(LAGLIDADG_3)PF14890(Intein_splicing) | 4 | PHE A 363LEU A 278LEU A 137LEU A 140 | None | 0.99A | 2bfpB-2cw7A:undetectable | 2bfpB-2cw7A:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fck | RIBOSOMAL-PROTEIN-SERINEACETYLTRANSFERASE,PUTATIVE (Vibrio cholerae) |
PF13302(Acetyltransf_3) | 4 | PHE A 89LEU A 127LEU A 132LEU A 98 | NO3 A 310 ( 3.7A)NO3 A 310 ( 4.5A)NoneNone | 0.94A | 2bfpB-2fckA:undetectable | 2bfpB-2fckA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i14 | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Pyrococcusfuriosus) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 4 | PHE A 22TYR A 21LEU A 106LEU A 105 | None | 0.97A | 2bfpB-2i14A:undetectable | 2bfpB-2i14A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3d | HYPOTHETICAL PROTEINATU1826 (Agrobacteriumfabrum) |
PF02129(Peptidase_S15) | 4 | SER A 71PHE A 63LEU A 31LEU A 82 | None | 0.91A | 2bfpB-2i3dA:6.6 | 2bfpB-2i3dA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ixn | SERINE/THREONINE-PROTEIN PHOSPHATASE 2AACTIVATOR 2 (Saccharomycescerevisiae) |
PF03095(PTPA) | 5 | SER A 49PHE A 152LEU A 143LEU A 59LEU A 58 | None | 1.20A | 2bfpB-2ixnA:undetectable | 2bfpB-2ixnA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ixn | SERINE/THREONINE-PROTEIN PHOSPHATASE 2AACTIVATOR 2 (Saccharomycescerevisiae) |
PF03095(PTPA) | 5 | SER A 106PHE A 104LEU A 58LEU A 142LEU A 143 | None | 1.37A | 2bfpB-2ixnA:undetectable | 2bfpB-2ixnA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2msk | NITROGEN REGULATIONPROTEIN NR(I) (Salmonellaenterica) |
PF00072(Response_reg) | 4 | PHE A 106ASP A 10LEU A 52LEU A 23 | None | 0.95A | 2bfpB-2mskA:undetectable | 2bfpB-2mskA:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o01 | PHOTOSYSTEM IREACTION CENTERSUBUNIT XI,CHLOROPLAST (Spinaciaoleracea) |
PF02605(PsaL) | 4 | PHE L 143LEU L 95LEU L 64LEU L 63 | NoneNoneNoneCLA L1502 (-4.2A) | 1.01A | 2bfpB-2o01L:undetectable | 2bfpB-2o01L:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2obe | HEXON (HumanmastadenovirusE) |
PF01065(Adeno_hexon)PF03678(Adeno_hexon_C) | 4 | ARG A 656SER A 861LEU A 353LEU A 627 | MPD A1706 (-3.6A)NoneNoneNone | 1.00A | 2bfpB-2obeA:undetectable | 2bfpB-2obeA:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pcq | PUTATIVEDIHYDRODIPICOLINATESYNTHASE (Thermusthermophilus) |
PF00701(DHDPS) | 4 | SER A 263PHE A 269LEU A 229LEU A 248 | None | 0.98A | 2bfpB-2pcqA:undetectable | 2bfpB-2pcqA:24.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qhx | PTERIDINE REDUCTASE1 (Leishmaniamajor) |
PF00106(adh_short)PF13561(adh_short_C2) | 8 | ARG A 17SER A 111PHE A 113ASP A 181LEU A 188TYR A 194LEU A 226LEU A 229 | NAP A1300 ( 3.7A)FE1 A1301 ( 2.8A)FE1 A1301 (-3.4A)NAP A1300 ( 3.6A)FE1 A1301 (-4.5A)FE1 A1301 ( 4.5A)FE1 A1301 ( 4.9A)None | 0.34A | 2bfpB-2qhxA:46.4 | 2bfpB-2qhxA:87.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qhx | PTERIDINE REDUCTASE1 (Leishmaniamajor) |
PF00106(adh_short)PF13561(adh_short_C2) | 5 | SER A 111PHE A 113LEU A 188TYR A 194LEU A 226 | FE1 A1301 ( 2.8A)FE1 A1301 (-3.4A)FE1 A1301 (-4.5A)FE1 A1301 ( 4.5A)FE1 A1301 ( 4.9A) | 0.80A | 2bfpB-2qhxA:46.4 | 2bfpB-2qhxA:87.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uy3 | ENDOCHITINASE (Saccharomycescerevisiae) |
PF00704(Glyco_hydro_18) | 4 | PHE A 71LEU A 105LEU A 67LEU A 83 | None | 0.94A | 2bfpB-2uy3A:3.5 | 2bfpB-2uy3A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vc6 | DIHYDRODIPICOLINATESYNTHASE (Sinorhizobiummeliloti) |
PF00701(DHDPS) | 4 | SER A 35LEU A 256LEU A 243LEU A 239 | None | 0.99A | 2bfpB-2vc6A:2.9 | 2bfpB-2vc6A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vlc | TYPE 2RIBOSOME-INACTIVATING PROTEIN CINNAMOMINIII (Cinnamomumcamphora) |
PF00161(RIP)PF00652(Ricin_B_lectin) | 4 | SER A 146LEU A 67TYR A 79LEU A 136 | None | 0.97A | 2bfpB-2vlcA:undetectable | 2bfpB-2vlcA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpw | HYPOTHETICALMEMBRANE SPANNINGPROTEIN (Thermusthermophilus) |
PF14589(NrfD_2) | 4 | SER C 169LEU C 37LEU C 157LEU C 179 | None | 0.78A | 2bfpB-2vpwC:undetectable | 2bfpB-2vpwC:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w6d | DYNAMIN FAMILYPROTEIN (Nostocpunctiforme) |
PF00350(Dynamin_N) | 4 | ARG A 299SER A 292LEU A 205LEU A 171 | NoneGDP A1696 (-4.6A)NoneNone | 0.97A | 2bfpB-2w6dA:undetectable | 2bfpB-2w6dA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wqw | INTERNALIN B (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 5 | SER A 49PHE A 53LEU A 105LEU A 116LEU A 119 | None | 1.41A | 2bfpB-2wqwA:undetectable | 2bfpB-2wqwA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsc | PHOTOSYSTEM IREACTION CENTERSUBUNIT XI,CHLOROPLASTIC (Spinaciaoleracea) |
PF02605(PsaL) | 4 | PHE L 143LEU L 95LEU L 64LEU L 63 | NoneBCR L1169 ( 3.8A)NoneNone | 1.00A | 2bfpB-2wscL:undetectable | 2bfpB-2wscL:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xpi | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT CUT9ANAPHASE-PROMOTINGCOMPLEX SUBUNIT HCN1HCN1/CDC26,20SCYCLOSOME/APCCOMPLEX PROTEINHCN1, CHAPERONE-LIKEPROTEIN HCN1, HIGHCOPY SUPPRESSOR OFCUT9 PROTEIN 1 (Schizosaccharomycespombe) |
PF10471(ANAPC_CDC26)PF12895(ANAPC3)PF13181(TPR_8)PF13424(TPR_12) | 4 | SER A 399PHE A 396LEU B 3LEU A 358 | None | 0.91A | 2bfpB-2xpiA:undetectable | 2bfpB-2xpiA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xwu | IMPORTIN13 (Homo sapiens) |
PF03810(IBN_N)PF08389(Xpo1) | 4 | SER B 517LEU B 535LEU B 590LEU B 594 | None | 1.01A | 2bfpB-2xwuB:undetectable | 2bfpB-2xwuB:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y5q | INTERNALIN B (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 5 | SER A 49PHE A 53LEU A 105LEU A 116LEU A 119 | None | 1.41A | 2bfpB-2y5qA:undetectable | 2bfpB-2y5qA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z65 | TOLL-LIKE RECEPTOR4, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF11921(DUF3439)PF13306(LRR_5)PF13855(LRR_8) | 4 | PHE A 165LEU A 195LEU A 231LEU A 233 | None | 0.92A | 2bfpB-2z65A:undetectable | 2bfpB-2z65A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z80 | TOLL-LIKE RECEPTOR2, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF11921(DUF3439)PF13855(LRR_8) | 4 | PHE A 162LEU A 139LEU A 154LEU A 179 | None | 0.94A | 2bfpB-2z80A:undetectable | 2bfpB-2z80A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z81 | TOLL-LIKE RECEPTOR2, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Mus musculus) |
PF11921(DUF3439)PF13306(LRR_5)PF13516(LRR_6)PF13855(LRR_8) | 4 | PHE A 162LEU A 139LEU A 154LEU A 179 | None | 0.94A | 2bfpB-2z81A:undetectable | 2bfpB-2z81A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zvb | PRECORRIN-3C17-METHYLTRANSFERASE (Thermusthermophilus) |
PF00590(TP_methylase) | 4 | SER A 81LEU A 61LEU A 158LEU A 157 | None | 0.96A | 2bfpB-2zvbA:undetectable | 2bfpB-2zvbA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3u | MENAQUINONEBIOSYNTHETIC ENZYME (Thermusthermophilus) |
PF02621(VitK2_biosynth) | 4 | SER A 73LEU A 32LEU A 189LEU A 185 | None | 0.95A | 2bfpB-3a3uA:undetectable | 2bfpB-3a3uA:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a7k | HALORHODOPSIN (Natronomonaspharaonis) |
PF01036(Bac_rhodopsin) | 4 | ARG A 176TYR A 248LEU A 164LEU A 168 | None | 0.97A | 2bfpB-3a7kA:undetectable | 2bfpB-3a7kA:25.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9g | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrobaculumaerophilum) |
PF07995(GSDH) | 4 | PHE A 82LEU A 136LEU A 60LEU A 95 | None | 0.96A | 2bfpB-3a9gA:undetectable | 2bfpB-3a9gA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abz | BETA-GLUCOSIDASE I (Kluyveromycesmarxianus) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF07691(PA14)PF14310(Fn3-like) | 4 | SER A 117ASP A 152LEU A 169LEU A 174 | None | 0.94A | 2bfpB-3abzA:undetectable | 2bfpB-3abzA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3agb | RED CHLOROPHYLLCATABOLITEREDUCTASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF06405(RCC_reductase) | 4 | PHE A 151LEU A 69LEU A 155LEU A 165 | None | 0.92A | 2bfpB-3agbA:undetectable | 2bfpB-3agbA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiz | DNA POLYMERASESLIDING CLAMP C (Sulfurisphaeratokodaii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 4 | SER C 188LEU C 165LEU C 225LEU C 227 | None | 0.99A | 2bfpB-3aizC:undetectable | 2bfpB-3aizC:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ay0 | UNCHARACTERIZEDPROTEIN MJ0883 (Methanocaldococcusjannaschii) |
PF02475(Met_10) | 4 | ARG A 323SER A 319LEU A 19LEU A 60 | None | 0.96A | 2bfpB-3ay0A:undetectable | 2bfpB-3ay0A:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2d | CD180 ANTIGEN (Homo sapiens) |
PF00560(LRR_1)PF13855(LRR_8) | 4 | PHE A 166LEU A 156LEU A 151LEU A 148 | None | 0.89A | 2bfpB-3b2dA:undetectable | 2bfpB-3b2dA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3byd | BETA-LACTAMASE OXY-1 (Klebsiellaoxytoca) |
PF13354(Beta-lactamase2) | 4 | SER A 109ASP A 104LEU A 98LEU A 122 | None | 1.01A | 2bfpB-3bydA:undetectable | 2bfpB-3bydA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 4 | SER A 156PHE A 158LEU A 198LEU A 232 | None | 0.90A | 2bfpB-3d1jA:undetectable | 2bfpB-3d1jA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dw8 | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A55 KDA REGULATORYSUBUNIT B ALPHAISOFORM (Homo sapiens) |
no annotation | 4 | SER B 289PHE B 346LEU B 336LEU B 329 | None | 0.95A | 2bfpB-3dw8B:undetectable | 2bfpB-3dw8B:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ek2 | ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE(NADH) (Burkholderiapseudomallei) |
PF13561(adh_short_C2) | 4 | SER A 136LEU A 4LEU A 35LEU A 11 | None | 0.71A | 2bfpB-3ek2A:25.6 | 2bfpB-3ek2A:26.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f95 | BETA-GLUCOSIDASE (Pseudoalteromonassp. BB1) |
no annotation | 4 | SER A 749PHE A 747LEU A 791LEU A 782 | None | 0.83A | 2bfpB-3f95A:undetectable | 2bfpB-3f95A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f95 | BETA-GLUCOSIDASE (Pseudoalteromonassp. BB1) |
no annotation | 4 | SER A 749PHE A 747LEU A 791LEU A 782 | None | 0.96A | 2bfpB-3f95A:undetectable | 2bfpB-3f95A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gwe | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)SYNTHASE III (Burkholderiapseudomallei) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | SER A 171LEU A 328TYR A 124LEU A 320 | None | 0.89A | 2bfpB-3gweA:undetectable | 2bfpB-3gweA:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gwe | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)SYNTHASE III (Burkholderiapseudomallei) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | SER A 171LEU A 328TYR A 124LEU A 320 | None | 0.99A | 2bfpB-3gweA:undetectable | 2bfpB-3gweA:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3icu | E3 UBIQUITIN-PROTEINLIGASE RNF128 (Homo sapiens) |
PF02225(PA) | 4 | SER A 75LEU A 47LEU A 84LEU A 119 | None | 0.93A | 2bfpB-3icuA:undetectable | 2bfpB-3icuA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j0a | TOLL-LIKE RECEPTOR 5 (Homo sapiens) |
PF01582(TIR)PF13855(LRR_8) | 4 | SER A 542LEU A 504LEU A 528LEU A 525 | None | 0.97A | 2bfpB-3j0aA:undetectable | 2bfpB-3j0aA:15.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jxe | TRYPTOPHANYL-TRNASYNTHETASE (Pyrococcushorikoshii) |
PF00579(tRNA-synt_1b) | 4 | PHE A 104LEU A 65TYR A 68LEU A 46 | None | 0.79A | 2bfpB-3jxeA:3.5 | 2bfpB-3jxeA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k28 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE2 (Bacillusanthracis) |
PF00202(Aminotran_3) | 4 | SER A 375PHE A 361LEU A 402LEU A 394 | None | 0.97A | 2bfpB-3k28A:undetectable | 2bfpB-3k28A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k96 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE[NAD(P)+] (Coxiellaburnetii) |
PF01210(NAD_Gly3P_dh_N)PF07479(NAD_Gly3P_dh_C) | 4 | PHE A 174LEU A 20LEU A 165LEU A 154 | None | 0.99A | 2bfpB-3k96A:6.6 | 2bfpB-3k96A:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3llc | PUTATIVE HYDROLASE (Agrobacteriumvitis) |
PF12697(Abhydrolase_6) | 5 | SER A 79PHE A 71LEU A 42LEU A 92LEU A 96 | None | 1.14A | 2bfpB-3llcA:undetectable | 2bfpB-3llcA:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ly5 | ATP-DEPENDENT RNAHELICASE DDX18 (Homo sapiens) |
PF00270(DEAD) | 4 | PHE A 322LEU A 312LEU A 354LEU A 327 | None | 0.64A | 2bfpB-3ly5A:2.8 | 2bfpB-3ly5A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m4x | NOL1/NOP2/SUN FAMILYPROTEIN (Enterococcusfaecium) |
PF01189(Methyltr_RsmB-F)PF13636(Methyltranf_PUA)PF17125(Methyltr_RsmF_N)PF17126(RsmF_methylt_CI) | 4 | PHE A 175LEU A 132LEU A 362LEU A 365 | None | 1.00A | 2bfpB-3m4xA:6.1 | 2bfpB-3m4xA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n4p | TERMINASE SUBUNITUL89 PROTEIN (Humanbetaherpesvirus5) |
PF02499(DNA_pack_C) | 4 | ASP A 615LEU A 605LEU A 620LEU A 652 | None | 0.97A | 2bfpB-3n4pA:undetectable | 2bfpB-3n4pA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE GAMMA-SUBUNIT (Komagataellapastoris) |
no annotation | 4 | ARG I 300PHE I 289LEU I 245LEU I 269 | None | 1.00A | 2bfpB-3opyI:2.6 | 2bfpB-3opyI:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ov5 | UNCHARACTERIZEDPROTEIN (Xanthomonascitri) |
PF10671(TcpQ) | 4 | ASP A 86LEU A 68TYR A 81LEU A 89 | None | 0.99A | 2bfpB-3ov5A:undetectable | 2bfpB-3ov5A:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p1t | PUTATIVEHISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Burkholderiapseudomallei) |
PF00155(Aminotran_1_2) | 4 | PHE A 195LEU A 240TYR A 199LEU A 70 | None | 0.81A | 2bfpB-3p1tA:undetectable | 2bfpB-3p1tA:24.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ps0 | CRISPR-ASSOCIATEDPROTEIN, CSA2 (Sulfolobussolfataricus) |
PF01905(DevR) | 4 | SER A 60TYR A 57LEU A 318LEU A 314 | None | 0.87A | 2bfpB-3ps0A:undetectable | 2bfpB-3ps0A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q8d | DNA REPAIR PROTEINRECO (Escherichiacoli) |
PF02565(RecO_C)PF11967(RecO_N) | 4 | ARG A 194PHE A 134LEU A 96LEU A 142 | None | 0.97A | 2bfpB-3q8dA:undetectable | 2bfpB-3q8dA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpx | FAB C2507 HEAVYCHAIN (Homo sapiens;Rattusnorvegicus) |
PF07654(C1-set)PF07686(V-set) | 4 | SER H 61PHE H 68LEU H 86LEU H 20 | None | 0.99A | 2bfpB-3qpxH:undetectable | 2bfpB-3qpxH:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rg1 | CD180 MOLECULE (Bos taurus) |
PF00560(LRR_1)PF13855(LRR_8) | 4 | SER A 195LEU A 156LEU A 151LEU A 148 | None | 0.88A | 2bfpB-3rg1A:undetectable | 2bfpB-3rg1A:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6q | CD180 ANTIGEN (Mus musculus) |
PF13855(LRR_8) | 4 | PHE A 344LEU A 317LEU A 310LEU A 305 | None | 1.00A | 2bfpB-3t6qA:undetectable | 2bfpB-3t6qA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tkn | NUCLEOPORIN NUP82 (Saccharomycescerevisiae) |
no annotation | 4 | LEU A 294TYR A 295LEU A 350LEU A 327 | None | 0.96A | 2bfpB-3tknA:undetectable | 2bfpB-3tknA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqt | D-ALANINE--D-ALANINELIGASE (Coxiellaburnetii) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 4 | SER A 135LEU A 10LEU A 125LEU A 123 | None | 0.93A | 2bfpB-3tqtA:undetectable | 2bfpB-3tqtA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tw8 | DENNDOMAIN-CONTAININGPROTEIN 1B (Homo sapiens) |
PF02141(DENN)PF03455(dDENN)PF03456(uDENN) | 4 | SER A 321PHE A 319LEU A 359LEU A 284 | None | 0.83A | 2bfpB-3tw8A:undetectable | 2bfpB-3tw8A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u2p | RECEPTORTYROSINE-PROTEINKINASE ERBB-4 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 4 | PHE A 51LEU A 24LEU A 72LEU A 74 | None | 0.85A | 2bfpB-3u2pA:undetectable | 2bfpB-3u2pA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7u | RECEPTORTYROSINE-PROTEINKINASE ERBB-4 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 4 | PHE A 51LEU A 24LEU A 72LEU A 74 | None | 0.89A | 2bfpB-3u7uA:undetectable | 2bfpB-3u7uA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uit | INAD-LIKE PROTEIN,MAGUK P55 SUBFAMILYMEMBER 5, PROTEINLIN-7 HOMOLOG B (Homo sapiens;Mus musculus;Rattusnorvegicus) |
PF02828(L27)PF09045(L27_2)PF09060(L27_N) | 4 | PHE A 117LEU A 42LEU A 108LEU A 89 | None | 0.97A | 2bfpB-3uitA:undetectable | 2bfpB-3uitA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ukn | NOVEL PROTEINSIMILAR TOVERTEBRATE POTASSIUMVOLTAGE-GATEDCHANNEL, SUBFAMILY H(EAG-RELATED) FAMILY (Danio rerio) |
PF00027(cNMP_binding) | 4 | PHE A 730LEU A 688LEU A 738LEU A 682 | None | 0.98A | 2bfpB-3uknA:undetectable | 2bfpB-3uknA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v44 | TOLL-LIKE RECEPTOR5B AND VARIABLELYMPHOCYTE RECEPTORB.61 CHIMERICPROTEIN (Danio rerio;Eptatretusburgeri) |
PF11921(DUF3439)PF13855(LRR_8) | 5 | SER A 66PHE A 92LEU A 101LEU A 109LEU A 111 | None | 1.46A | 2bfpB-3v44A:undetectable | 2bfpB-3v44A:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vkg | DYNEIN HEAVY CHAIN,CYTOPLASMIC (Dictyosteliumdiscoideum) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | ARG A3767SER A3912LEU A4133LEU A4204 | None | 0.95A | 2bfpB-3vkgA:undetectable | 2bfpB-3vkgA:6.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vkg | DYNEIN HEAVY CHAIN,CYTOPLASMIC (Dictyosteliumdiscoideum) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | PHE A2538TYR A2430LEU A2577LEU A2581 | None | 0.96A | 2bfpB-3vkgA:undetectable | 2bfpB-3vkgA:6.85 |