SIMILAR PATTERNS OF AMINO ACIDS FOR 2BDM_A_TMIA502

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a7j PHOSPHORIBULOKINASE

(Rhodobacter
sphaeroides)
PF00485
(PRK)
5 LEU A 127
ILE A 152
LEU A 276
THR A 277
LEU A 279
None
0.71A 2bdmA-1a7jA:
0.0
2bdmA-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amo NADPH-CYTOCHROME
P450 REDUCTASE


(Rattus
norvegicus)
PF00175
(NAD_binding_1)
PF00258
(Flavodoxin_1)
PF00667
(FAD_binding_1)
5 LEU A 371
LEU A 330
ILE A 377
ILE A 427
LEU A 338
None
1.03A 2bdmA-1amoA:
0.0
2bdmA-1amoA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b47 CBL

(Homo sapiens)
PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3)
5 LEU A  88
LEU A 151
THR A 152
LEU A 154
PHE A 158
None
0.81A 2bdmA-1b47A:
0.0
2bdmA-1b47A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b47 CBL

(Homo sapiens)
PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3)
5 LEU A  88
THR A 152
LEU A 154
SER A 155
PHE A 158
None
0.80A 2bdmA-1b47A:
0.0
2bdmA-1b47A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0c SULFURTRANSFERASE

(Azotobacter
vinelandii)
PF00581
(Rhodanese)
5 LEU A 215
ILE A 211
ILE A 207
LEU A 238
LEU A 241
None
0.89A 2bdmA-1e0cA:
0.0
2bdmA-1e0cA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0c SULFURTRANSFERASE

(Azotobacter
vinelandii)
PF00581
(Rhodanese)
5 LEU A 246
ILE A 211
ILE A 207
LEU A 238
LEU A 241
None
1.00A 2bdmA-1e0cA:
0.0
2bdmA-1e0cA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbv SIGNAL TRANSDUCTION
PROTEIN CBL


(Homo sapiens)
PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3)
PF14447
(Prok-RING_4)
5 LEU A  88
LEU A 151
THR A 152
LEU A 154
PHE A 158
None
0.74A 2bdmA-1fbvA:
0.0
2bdmA-1fbvA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbv SIGNAL TRANSDUCTION
PROTEIN CBL


(Homo sapiens)
PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3)
PF14447
(Prok-RING_4)
5 LEU A  88
THR A 152
LEU A 154
SER A 155
PHE A 158
None
0.71A 2bdmA-1fbvA:
0.0
2bdmA-1fbvA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g5g FUSION PROTEIN

(Avian
avulavirus 1)
PF00523
(Fusion_gly)
5 ILE A  63
ASN A  85
LEU A  88
THR A  89
LEU A  91
None
NAG  A 851 (-1.8A)
None
NAG  A 851 (-4.1A)
None
0.75A 2bdmA-1g5gA:
0.0
2bdmA-1g5gA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1in8 HOLLIDAY JUNCTION
DNA HELICASE RUVB


(Thermotoga
maritima)
PF05491
(RuvB_C)
PF05496
(RuvB_N)
5 LEU A  24
ILE A  70
ILE A  71
LEU A  56
LEU A 175
None
0.86A 2bdmA-1in8A:
0.0
2bdmA-1in8A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl0 S-ADENOSYLMETHIONINE
DECARBOXYLASE
PROENZYME


(Homo sapiens)
PF01536
(SAM_decarbox)
5 LEU A 180
ILE A 268
LEU A 177
THR A 176
LEU A 284
None
None
None
PUT  A 401 (-3.7A)
None
1.06A 2bdmA-1jl0A:
0.0
2bdmA-1jl0A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7j PROTEIN YCIO

(Escherichia
coli)
PF01300
(Sua5_yciO_yrdC)
5 LEU A 136
LEU A 133
LEU A  67
THR A  66
LEU A 141
None
None
None
SO4  A 207 (-4.7A)
None
0.97A 2bdmA-1k7jA:
0.0
2bdmA-1k7jA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd1 PROTEIN TRANSPORT
PROTEIN SEC24


(Saccharomyces
cerevisiae)
PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS)
5 LEU A 871
LEU A 808
LEU A 859
ILE A 856
LEU A 759
None
0.97A 2bdmA-1pd1A:
undetectable
2bdmA-1pd1A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh4 CREATINE KINASE

(Gallus gallus)
PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN)
5 LEU A 162
LEU A 165
ILE A 260
THR A 224
LEU A 226
None
1.06A 2bdmA-1qh4A:
undetectable
2bdmA-1qh4A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qju PROTEIN VP1

(Rhinovirus A)
PF00073
(Rhv)
5 LEU 1 181
ILE 1 122
ILE 1 236
LEU 1 217
THR 1 216
W01  17001 (-4.6A)
W01  17001 ( 4.6A)
W01  17001 ( 4.9A)
W01  17001 (-4.2A)
None
1.02A 2bdmA-1qju1:
undetectable
2bdmA-1qju1:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tki TITIN

(Homo sapiens)
PF00069
(Pkinase)
5 ILE A 150
LEU A 209
THR A 208
LEU A 206
SER A 205
None
1.05A 2bdmA-1tkiA:
undetectable
2bdmA-1tkiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy8 NP95-LIKE RING
FINGER PROTEIN,
ISOFORM A


(Homo sapiens)
PF00240
(ubiquitin)
5 LEU A  52
ILE A  76
ILE A  10
LEU A  65
THR A  64
None
1.02A 2bdmA-1wy8A:
undetectable
2bdmA-1wy8A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyd HYPOTHETICAL
ASPARTYL-TRNA
SYNTHETASE


(Sulfurisphaera
tokodaii)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
5 LEU A 242
ILE A 245
ILE A 249
LEU A 404
LEU A 401
None
0.80A 2bdmA-1wydA:
undetectable
2bdmA-1wydA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a0s 6-PYRUVOYL
TETRAHYDROPTERIN
SYNTHASE


(Plasmodium
vivax)
PF01242
(PTPS)
5 LEU A 154
LEU A 151
ILE A 180
LEU A 142
LEU A 145
None
1.07A 2bdmA-2a0sA:
undetectable
2bdmA-2a0sA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4y FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 1


(Salmonella
enterica)
no annotation 6 ILE A 133
ILE A 433
LEU A 119
THR A 118
LEU A 116
PHE A 112
None
0.92A 2bdmA-2d4yA:
0.6
2bdmA-2d4yA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4y FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 1


(Salmonella
enterica)
no annotation 6 ILE A 133
ILE A 433
LEU A 119
THR A 118
LEU A 116
SER A 115
None
0.98A 2bdmA-2d4yA:
0.6
2bdmA-2d4yA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4y FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 1


(Salmonella
enterica)
no annotation 5 PHE A 326
ILE A 433
LEU A 119
THR A 118
LEU A 116
None
1.01A 2bdmA-2d4yA:
0.6
2bdmA-2d4yA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i79 ACETYLTRANSFERASE,
GNAT FAMILY


(Streptococcus
pneumoniae)
PF00583
(Acetyltransf_1)
5 LEU A 121
LEU A 124
LEU A  90
ILE A  76
ILE A  60
None
1.06A 2bdmA-2i79A:
undetectable
2bdmA-2i79A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans)
PF01933
(UPF0052)
5 LEU A 132
ILE A 148
ILE A 155
LEU A 188
SER A 187
None
None
None
None
SO4  A 324 ( 3.5A)
0.86A 2bdmA-2o2zA:
undetectable
2bdmA-2o2zA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odh R.BCNI

(Brevibacillus
centrosporus)
PF15515
(MvaI_BcnI)
5 LEU A  75
ILE A 153
ILE A 185
THR A 189
LEU A 191
None
1.03A 2bdmA-2odhA:
undetectable
2bdmA-2odhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmt GLUTATHIONE
TRANSFERASE


(Proteus
mirabilis)
PF00043
(GST_C)
PF02798
(GST_N)
5 LEU A  18
LEU A  23
LEU A  76
ASN A  59
LEU A  57
None
1.08A 2bdmA-2pmtA:
3.2
2bdmA-2pmtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pts ADENYLOSUCCINATE
LYASE


(Escherichia
coli)
PF00206
(Lyase_1)
PF08328
(ASL_C)
5 LEU A 135
ILE A 350
ASN A 318
LEU A 321
LEU A 324
None
0.96A 2bdmA-2ptsA:
1.9
2bdmA-2ptsA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pts ADENYLOSUCCINATE
LYASE


(Escherichia
coli)
PF00206
(Lyase_1)
PF08328
(ASL_C)
6 PHE A  27
LEU A 198
ILE A 143
ILE A 350
ASN A 318
LEU A 321
None
1.15A 2bdmA-2ptsA:
1.9
2bdmA-2ptsA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkd ZINC FINGER PROTEIN
ZPR1


(Mus musculus)
PF03367
(zf-ZPR1)
5 LEU A 391
ILE A 394
LEU A 354
THR A 353
LEU A 357
None
0.90A 2bdmA-2qkdA:
undetectable
2bdmA-2qkdA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5s PROCESSED GLYCEROL
PHOSPHATE
LIPOTEICHOIC ACID
SYNTHASE


(Staphylococcus
aureus)
PF00884
(Sulfatase)
5 PHE A 285
LEU A 452
LEU A 410
ILE A 252
ILE A 470
None
0.89A 2bdmA-2w5sA:
undetectable
2bdmA-2w5sA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnt RIBOSOMAL PROTEIN S6
KINASE


(Homo sapiens)
PF00069
(Pkinase)
5 LEU A 497
LEU A 498
LEU A 502
ILE A 501
LEU A 604
None
0.95A 2bdmA-2wntA:
undetectable
2bdmA-2wntA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa7 ADAPTOR-RELATED
PROTEIN COMPLEX 2,
ALPHA 2 SUBUNIT


(Rattus
norvegicus)
PF01602
(Adaptin_N)
5 PHE A  97
ILE A  72
ASN A  34
LEU A  37
PHE A  44
None
0.97A 2bdmA-2xa7A:
undetectable
2bdmA-2xa7A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xka FTSZ/TUBULIN-RELATED
PROTEIN


(Bacillus
thuringiensis)
PF00091
(Tubulin)
5 LEU A 274
LEU A 270
ILE A  23
ILE A  21
THR A 247
None
0.91A 2bdmA-2xkaA:
undetectable
2bdmA-2xkaA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv7 CG10997-PA

(Drosophila
melanogaster)
no annotation 5 LEU A 204
LEU A 201
ILE A 197
ILE A 185
LEU A 147
None
1.05A 2bdmA-2yv7A:
undetectable
2bdmA-2yv7A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyz PUTATIVE
UNCHARACTERIZED
PROTEIN PAE0789
TRNA-SPLICING
ENDONUCLEASE


(Pyrobaculum
aerophilum)
PF01974
(tRNA_int_endo)
PF02778
(tRNA_int_endo_N)
no annotation
5 LEU A  68
ILE B 142
LEU B 163
THR B 162
LEU B 176
None
0.83A 2bdmA-2zyzA:
undetectable
2bdmA-2zyzA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahr ERO1-LIKE PROTEIN
ALPHA


(Homo sapiens)
PF04137
(ERO1)
5 LEU A  65
LEU A  68
LEU A 344
ILE A 347
ILE A 351
None
1.01A 2bdmA-3ahrA:
undetectable
2bdmA-3ahrA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bbh RIBOSOME BIOGENESIS
PROTEIN NEP1-LIKE


(Methanocaldococcus
jannaschii)
PF03587
(EMG1)
5 ILE A 138
ILE A 160
LEU A 126
THR A 125
LEU A 129
None
0.98A 2bdmA-3bbhA:
undetectable
2bdmA-3bbhA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bit FACT COMPLEX SUBUNIT
SPT16


(Saccharomyces
cerevisiae)
PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob)
5 LEU A  84
LEU A   4
ASN A 296
LEU A  55
PHE A  11
None
1.07A 2bdmA-3bitA:
undetectable
2bdmA-3bitA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ek1 ALDEHYDE
DEHYDROGENASE


(Brucella
abortus)
PF00171
(Aldedh)
5 LEU A   4
LEU A   2
LEU A 188
THR A 189
LEU A 191
None
0.84A 2bdmA-3ek1A:
undetectable
2bdmA-3ek1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ep7 S-ADENOSYLMETHIONINE
DECARBOXYLASE ALPHA
CHAIN


(Homo sapiens)
PF01536
(SAM_decarbox)
5 LEU A 180
ILE A 268
LEU A 177
THR A 176
LEU A 284
None
1.07A 2bdmA-3ep7A:
undetectable
2bdmA-3ep7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fb4 ADENYLATE KINASE

(Jeotgalibacillus
marinus)
PF00406
(ADK)
PF05191
(ADK_lid)
5 ILE A  26
ILE A   3
ASN A 209
LEU A 212
LEU A 215
None
0.91A 2bdmA-3fb4A:
undetectable
2bdmA-3fb4A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxs THIOREDOXIN

(Bacteroides
fragilis)
PF00085
(Thioredoxin)
5 LEU A 138
LEU A 139
ILE A  84
ILE A  86
LEU A 130
None
0.99A 2bdmA-3hxsA:
undetectable
2bdmA-3hxsA:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2j PROTEIN POLYBROMO-1

(Homo sapiens)
PF00439
(Bromodomain)
5 PHE A 424
LEU A 398
LEU A 405
ILE A 401
LEU A 357
None
1.07A 2bdmA-3k2jA:
undetectable
2bdmA-3k2jA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcx SUSD SUPERFAMILY
PROTEIN


(Bacteroides
thetaiotaomicron)
PF07980
(SusD_RagB)
PF14322
(SusD-like_3)
5 LEU A 423
LEU A 427
ILE A 426
ASN A 234
LEU A 233
None
0.91A 2bdmA-3mcxA:
0.6
2bdmA-3mcxA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ni8 PFC0360W PROTEIN

(Plasmodium
falciparum)
PF08327
(AHSA1)
5 ILE A  70
LEU A  44
THR A  45
LEU A  47
SER A  48
None
IPA  A 159 ( 4.7A)
None
None
None
0.98A 2bdmA-3ni8A:
undetectable
2bdmA-3ni8A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oc6 6-PHOSPHOGLUCONOLACT
ONASE


(Mycolicibacterium
smegmatis)
PF01182
(Glucosamine_iso)
5 LEU A  92
LEU A  93
ILE A  96
ILE A  61
THR A  38
None
1.01A 2bdmA-3oc6A:
undetectable
2bdmA-3oc6A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli)
PF02395
(Peptidase_S6)
5 LEU A 639
ILE A 556
ASN A 515
LEU A 544
PHE A 646
None
1.05A 2bdmA-3szeA:
undetectable
2bdmA-3szeA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tvi ASPARTOKINASE

(Clostridium
acetobutylicum)
PF00696
(AA_kinase)
PF01842
(ACT)
5 ILE A 407
ASN A 391
THR A 395
LEU A 397
SER A 398
None
0.59A 2bdmA-3tviA:
2.1
2bdmA-3tviA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vgo E3 UBIQUITIN-PROTEIN
LIGASE CBL-B


(Homo sapiens)
PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3)
5 LEU A  78
LEU A 143
THR A 144
LEU A 146
PHE A 150
None
0.89A 2bdmA-3vgoA:
undetectable
2bdmA-3vgoA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbk EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5B


(Saccharomyces
cerevisiae)
PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2)
5 LEU A 592
LEU A 575
ILE A 572
LEU A 566
SER A 565
None
0.92A 2bdmA-3wbkA:
undetectable
2bdmA-3wbkA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpp CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN


(Streptococcus
pneumoniae)
PF12708
(Pectate_lyase_3)
PF13229
(Beta_helix)
5 LEU A 517
LEU A 510
ILE A 533
ASN A 494
THR A 492
None
1.02A 2bdmA-3zppA:
undetectable
2bdmA-3zppA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b18 IMPORTIN SUBUNIT
ALPHA-1


(Homo sapiens)
PF00514
(Arm)
PF16186
(Arm_3)
5 LEU A 305
LEU A 317
ILE A 362
LEU A 347
LEU A 344
None
1.05A 2bdmA-4b18A:
undetectable
2bdmA-4b18A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4d FERREDOXIN-NADP
REDUCTASE


(Xanthomonas
citri)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6)
5 LEU A 205
ILE A 140
LEU A 192
THR A 193
LEU A 195
None
None
None
CL  A1261 (-4.0A)
None
0.73A 2bdmA-4b4dA:
undetectable
2bdmA-4b4dA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8c GLUCOSE-REPRESSIBLE
ALCOHOL
DEHYDROGENASE
TRANSCRIPTIONAL
EFFECTOR


(Saccharomyces
cerevisiae)
PF03372
(Exo_endo_phos)
PF13855
(LRR_8)
5 LEU D 399
LEU D 379
ILE D 376
LEU D 364
PHE D 408
None
0.97A 2bdmA-4b8cD:
undetectable
2bdmA-4b8cD:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8j IMPORTIN SUBUNIT
ALPHA-1A


(Oryza sativa)
PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3)
5 LEU A 293
LEU A 305
ILE A 351
LEU A 335
LEU A 332
None
1.01A 2bdmA-4b8jA:
undetectable
2bdmA-4b8jA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bpl IMPORTIN SUBUNIT
ALPHA-1A


(Oryza sativa)
PF00514
(Arm)
PF16186
(Arm_3)
5 LEU A 293
LEU A 305
ILE A 351
LEU A 335
LEU A 332
None
0.95A 2bdmA-4bplA:
undetectable
2bdmA-4bplA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4efh ACTIN-1

(Acanthamoeba
castellanii)
PF00022
(Actin)
5 LEU A 242
ILE A 208
ILE A 212
LEU A 193
THR A 194
None
0.93A 2bdmA-4efhA:
undetectable
2bdmA-4efhA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eku PROTEIN-TYROSINE
KINASE 2-BETA


(Homo sapiens)
PF00373
(FERM_M)
5 LEU A 299
LEU A 279
ILE A 286
ILE A 348
LEU A 320
None
1.06A 2bdmA-4ekuA:
undetectable
2bdmA-4ekuA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gha POLYMERASE COFACTOR
VP35


(Marburg
marburgvirus)
PF02097
(Filo_VP35)
5 LEU A 266
THR A 267
LEU A 269
SER A 270
PHE A 276
None
G  J  12 ( 3.4A)
None
None
None
0.83A 2bdmA-4ghaA:
undetectable
2bdmA-4ghaA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gvl TRKA DOMAIN PROTEIN

(Geobacter
sulfurreducens)
PF02080
(TrkA_C)
PF02254
(TrkA_N)
5 LEU A 323
ILE A 292
ILE A 297
LEU A 331
LEU A 280
None
1.00A 2bdmA-4gvlA:
undetectable
2bdmA-4gvlA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13


(Thermus
thermophilus)
PF00361
(Proton_antipo_M)
5 PHE M 194
LEU M 260
LEU M 261
ILE M 246
LEU M 465
None
1.05A 2bdmA-4heaM:
0.7
2bdmA-4heaM:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j1s POLYKETIDE SYNTHASE
PKSJ


(Bacillus
subtilis)
PF08659
(KR)
5 LEU A  82
LEU A 119
ILE A  87
ILE A  27
LEU A  74
None
0.86A 2bdmA-4j1sA:
undetectable
2bdmA-4j1sA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l8p BILE ACID
7A-DEHYDRATASE, BAIE


([Clostridium]
hiranonis)
PF13577
(SnoaL_4)
5 LEU A  26
ILE A 139
LEU A  42
LEU A  34
PHE A  31
None
1PE  A 204 ( 4.6A)
None
None
None
1.03A 2bdmA-4l8pA:
undetectable
2bdmA-4l8pA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5p NADPH DEHYDROGENASE

(Scheffersomyces
stipitis)
PF00724
(Oxidored_FMN)
5 LEU A 199
LEU A 222
ILE A 221
ILE A 239
PHE A 263
None
1.00A 2bdmA-4m5pA:
undetectable
2bdmA-4m5pA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 LEU A 421
LEU A 423
THR A 386
LEU A 388
SER A 389
None
1.02A 2bdmA-4m7eA:
undetectable
2bdmA-4m7eA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7e PROTEIN
BRASSINOSTEROID
INSENSITIVE 1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 LEU A 423
LEU A 385
THR A 386
LEU A 388
SER A 389
None
1.05A 2bdmA-4m7eA:
undetectable
2bdmA-4m7eA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mag SIALIC ACID BINDING
PROTEIN


(Vibrio cholerae)
PF03480
(DctP)
5 ILE A 231
ILE A 232
LEU A   4
THR A   3
LEU A  37
None
1.07A 2bdmA-4magA:
undetectable
2bdmA-4magA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6f PUTATIVE THIOSUGAR
SYNTHASE


(Amycolatopsis
orientalis)
PF05690
(ThiG)
5 LEU A  43
ILE A  30
ILE A  52
LEU A 215
THR A 214
None
0.96A 2bdmA-4n6fA:
undetectable
2bdmA-4n6fA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rt6 HEME/HEMOPEXIN-BINDI
NG PROTEIN


(Haemophilus
influenzae)
PF05860
(Haemagg_act)
5 LEU A 255
ILE A 279
ILE A 301
ASN A 365
LEU A 361
None
1.01A 2bdmA-4rt6A:
undetectable
2bdmA-4rt6A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uad IMPORTIN SUBUNIT
ALPHA-7


(Homo sapiens)
PF00514
(Arm)
PF16186
(Arm_3)
5 LEU A 303
LEU A 315
ILE A 360
LEU A 345
LEU A 342
None
1.04A 2bdmA-4uadA:
undetectable
2bdmA-4uadA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd9 NISIN BIOSYNTHESIS
PROTEIN NISB


(Lactococcus
lactis)
PF04738
(Lant_dehydr_N)
PF14028
(Lant_dehydr_C)
5 LEU A 738
LEU A 740
ILE A 817
LEU A 800
PHE A 793
None
0.97A 2bdmA-4wd9A:
1.8
2bdmA-4wd9A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y68 PUTATIVE
NISIN-RESISTANCE
PROTEIN


(Streptococcus
agalactiae)
no annotation 5 LEU C 313
LEU C 122
ILE C 126
THR C 130
LEU C 163
None
0.99A 2bdmA-4y68C:
undetectable
2bdmA-4y68C:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7x MDBA

(Actinomyces
oris)
PF13462
(Thioredoxin_4)
5 LEU A 164
LEU A 131
LEU A 289
ILE A 153
THR A 270
None
0.95A 2bdmA-4z7xA:
undetectable
2bdmA-4z7xA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxi TYROCIDINE
SYNTHETASE 3


(Acinetobacter
baumannii)
PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C)
5 PHE A 424
ILE A 401
LEU A 265
LEU A 268
SER A 269
None
0.90A 2bdmA-4zxiA:
undetectable
2bdmA-4zxiA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1n AMINOACYL TRNA
SYNTHASE
COMPLEX-INTERACTING
MULTIFUNCTIONAL
PROTEIN 2


(Homo sapiens)
PF00043
(GST_C)
5 PHE B 199
LEU B 112
LEU B 108
ILE B 122
LEU B 217
None
1.02A 2bdmA-5a1nB:
undetectable
2bdmA-5a1nB:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5axi E3 UBIQUITIN-PROTEIN
LIGASE CBL-B


(Mus musculus)
PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3)
5 LEU A  78
LEU A 143
THR A 144
LEU A 146
PHE A 150
None
0.72A 2bdmA-5axiA:
undetectable
2bdmA-5axiA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5axi E3 UBIQUITIN-PROTEIN
LIGASE CBL-B


(Mus musculus)
PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3)
5 LEU A  78
THR A 144
LEU A 146
SER A 147
PHE A 150
None
0.77A 2bdmA-5axiA:
undetectable
2bdmA-5axiA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bsz N-METHYLTRANSFERASE

(Streptoalloteichus
sp. ATCC 53650)
PF13649
(Methyltransf_25)
5 LEU A 218
LEU A 215
LEU A 228
THR A 229
LEU A 238
None
0.97A 2bdmA-5bszA:
undetectable
2bdmA-5bszA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bvr ALPHA-ACTININ-LIKE
PROTEIN 1


(Schizosaccharomyces
pombe)
PF00307
(CH)
5 LEU A  37
LEU A  99
ILE A 102
THR A  13
PHE A  18
None
0.99A 2bdmA-5bvrA:
0.9
2bdmA-5bvrA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c30 RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus)
PF02026
(RyR)
5 LEU A 874
ILE A 870
LEU A 932
THR A 931
LEU A 933
None
1.07A 2bdmA-5c30A:
undetectable
2bdmA-5c30A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cth BIDIRECTIONAL SUGAR
TRANSPORTER SWEET2B


(Oryza sativa)
PF03083
(MtN3_slv)
5 LEU A  49
LEU A  52
LEU A  85
ILE A  88
ILE A  92
None
0.67A 2bdmA-5cthA:
undetectable
2bdmA-5cthA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN


([Candida]
glabrata)
PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central)
5 LEU A 684
ILE A 860
ILE A 862
LEU A 734
THR A 733
None
0.61A 2bdmA-5d0fA:
1.6
2bdmA-5d0fA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dm4 METHYLTRANSFERASE
DOMAIN FAMILY


(Bacillus
pumilus)
PF13489
(Methyltransf_23)
5 ILE A 155
ILE A 157
LEU A 198
THR A 199
LEU A 197
None
1.05A 2bdmA-5dm4A:
undetectable
2bdmA-5dm4A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4v NUCLEOPROTEIN,PHOSPH
OPROTEIN


(Measles
morbillivirus)
PF00973
(Paramyxo_ncap)
PF13825
(Paramyxo_PNT)
5 LEU A  33
LEU A 148
ILE A 151
ILE A 155
LEU A  58
None
0.86A 2bdmA-5e4vA:
0.8
2bdmA-5e4vA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fby CLEAVED PEPTIDE
SEPARASE


(Chaetomium
thermophilum;
synthetic
construct)
PF03568
(Peptidase_C50)
no annotation
5 LEU B  13
LEU A1699
ILE A1702
ILE A1707
SER A1718
None
0.66A 2bdmA-5fbyB:
undetectable
2bdmA-5fbyB:
5.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxu NADPH--CYTOCHROME
P450 REDUCTASE 2


(Arabidopsis
thaliana)
PF00175
(NAD_binding_1)
PF00258
(Flavodoxin_1)
PF00667
(FAD_binding_1)
5 LEU A 231
LEU A 258
LEU A 262
ILE A 261
THR A 106
None
1.07A 2bdmA-5gxuA:
3.2
2bdmA-5gxuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8w ATP-DEPENDENT DNA
HELICASE TA0057


(Thermoplasma
acidophilum)
PF06733
(DEAD_2)
PF06777
(HBB)
PF13307
(Helicase_C_2)
5 PHE A 397
LEU A 210
LEU A  57
LEU A  55
ILE A 208
None
1.06A 2bdmA-5h8wA:
undetectable
2bdmA-5h8wA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijj SPX DOMAIN

(Chaetomium
thermophilum)
PF03105
(SPX)
5 LEU A 105
LEU A 102
ILE A 166
ILE A 162
THR A  82
None
1.04A 2bdmA-5ijjA:
undetectable
2bdmA-5ijjA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip7 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3


(Saccharomyces
cerevisiae)
PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L)
5 LEU C  72
ILE C  70
ILE C 144
LEU C 101
THR C 100
None
1.07A 2bdmA-5ip7C:
undetectable
2bdmA-5ip7C:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrw POTASSIUM-TRANSPORTI
NG ATPASE
POTASSIUM-BINDING
SUBUNIT


(Escherichia
coli)
PF03814
(KdpA)
5 LEU A 380
ILE A 148
ILE A 145
LEU A  27
LEU A  30
None
0.98A 2bdmA-5mrwA:
undetectable
2bdmA-5mrwA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd7 KINESIN-LIKE PROTEIN
KIF20A


(Mus musculus)
PF00225
(Kinesin)
5 PHE C 305
LEU C 408
ILE C 307
LEU C 463
THR C 464
None
1.00A 2bdmA-5nd7C:
undetectable
2bdmA-5nd7C:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0x PUTATIVE FERRIC
REDUCTASE


(Cylindrospermum
stagnale)
PF08022
(FAD_binding_8)
PF08030
(NAD_binding_6)
5 LEU A 596
LEU A 563
ILE A 550
ILE A 546
LEU A 533
None
1.06A 2bdmA-5o0xA:
undetectable
2bdmA-5o0xA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txv ATP-DEPENDENT
PROTEASE ATPASE
SUBUNIT HSLU


(Escherichia
coli)
PF00004
(AAA)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small)
5 LEU A 399
LEU A 402
ILE A 376
ILE A 373
THR A 419
None
0.90A 2bdmA-5txvA:
undetectable
2bdmA-5txvA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5


(Homo sapiens)
PF01663
(Phosphodiest)
5 PHE A 359
LEU A 182
LEU A 184
ILE A 234
LEU A 373
None
1.05A 2bdmA-5vemA:
undetectable
2bdmA-5vemA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqi IMPORTIN SUBUNIT
ALPHA


(Neurospora
crassa)
no annotation 5 LEU B 302
LEU B 314
ILE B 359
LEU B 344
LEU B 341
None
1.05A 2bdmA-5vqiB:
undetectable
2bdmA-5vqiB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbl REGULATORY-ASSOCIATE
D PROTEIN OF TOR 1


(Arabidopsis
thaliana)
no annotation 5 LEU A 485
LEU A 482
LEU A 523
ILE A 526
ILE A 530
None
0.72A 2bdmA-5wblA:
undetectable
2bdmA-5wblA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbk IMPORTIN-4

(Homo sapiens)
no annotation 5 LEU D 989
LEU D 986
LEU D1023
ILE D1026
ILE D1030
None
0.94A 2bdmA-5xbkD:
undetectable
2bdmA-5xbkD:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9w POLLEN RECEPTOR-LIKE
KINASE 6


(Arabidopsis
thaliana)
no annotation 5 LEU B 194
LEU B 173
ILE B 212
ASN B 225
LEU B 222
None
1.05A 2bdmA-5y9wB:
undetectable
2bdmA-5y9wB:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yim SDEA

(Legionella
pneumophila)
no annotation 5 LEU A 708
LEU A 747
ILE A 740
LEU A 663
THR A 662
None
0.97A 2bdmA-5yimA:
undetectable
2bdmA-5yimA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cf8 LYTIC
TRANSGLYCOSYLASE


(Campylobacter
jejuni)
no annotation 5 LEU A 116
LEU A 135
THR A 136
LEU A 138
PHE A 142
None
SO4  A 704 (-4.5A)
None
None
None
0.77A 2bdmA-6cf8A:
undetectable
2bdmA-6cf8A:
10.49