SIMILAR PATTERNS OF AMINO ACIDS FOR 2BDM_A_TMIA502
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7j | PHOSPHORIBULOKINASE (Rhodobactersphaeroides) |
PF00485(PRK) | 5 | LEU A 127ILE A 152LEU A 276THR A 277LEU A 279 | None | 0.71A | 2bdmA-1a7jA:0.0 | 2bdmA-1a7jA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amo | NADPH-CYTOCHROMEP450 REDUCTASE (Rattusnorvegicus) |
PF00175(NAD_binding_1)PF00258(Flavodoxin_1)PF00667(FAD_binding_1) | 5 | LEU A 371LEU A 330ILE A 377ILE A 427LEU A 338 | None | 1.03A | 2bdmA-1amoA:0.0 | 2bdmA-1amoA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b47 | CBL (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 5 | LEU A 88LEU A 151THR A 152LEU A 154PHE A 158 | None | 0.81A | 2bdmA-1b47A:0.0 | 2bdmA-1b47A:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b47 | CBL (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 5 | LEU A 88THR A 152LEU A 154SER A 155PHE A 158 | None | 0.80A | 2bdmA-1b47A:0.0 | 2bdmA-1b47A:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e0c | SULFURTRANSFERASE (Azotobactervinelandii) |
PF00581(Rhodanese) | 5 | LEU A 215ILE A 211ILE A 207LEU A 238LEU A 241 | None | 0.89A | 2bdmA-1e0cA:0.0 | 2bdmA-1e0cA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e0c | SULFURTRANSFERASE (Azotobactervinelandii) |
PF00581(Rhodanese) | 5 | LEU A 246ILE A 211ILE A 207LEU A 238LEU A 241 | None | 1.00A | 2bdmA-1e0cA:0.0 | 2bdmA-1e0cA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbv | SIGNAL TRANSDUCTIONPROTEIN CBL (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3)PF14447(Prok-RING_4) | 5 | LEU A 88LEU A 151THR A 152LEU A 154PHE A 158 | None | 0.74A | 2bdmA-1fbvA:0.0 | 2bdmA-1fbvA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbv | SIGNAL TRANSDUCTIONPROTEIN CBL (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3)PF14447(Prok-RING_4) | 5 | LEU A 88THR A 152LEU A 154SER A 155PHE A 158 | None | 0.71A | 2bdmA-1fbvA:0.0 | 2bdmA-1fbvA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g5g | FUSION PROTEIN (Avianavulavirus 1) |
PF00523(Fusion_gly) | 5 | ILE A 63ASN A 85LEU A 88THR A 89LEU A 91 | NoneNAG A 851 (-1.8A)NoneNAG A 851 (-4.1A)None | 0.75A | 2bdmA-1g5gA:0.0 | 2bdmA-1g5gA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1in8 | HOLLIDAY JUNCTIONDNA HELICASE RUVB (Thermotogamaritima) |
PF05491(RuvB_C)PF05496(RuvB_N) | 5 | LEU A 24ILE A 70ILE A 71LEU A 56LEU A 175 | None | 0.86A | 2bdmA-1in8A:0.0 | 2bdmA-1in8A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl0 | S-ADENOSYLMETHIONINEDECARBOXYLASEPROENZYME (Homo sapiens) |
PF01536(SAM_decarbox) | 5 | LEU A 180ILE A 268LEU A 177THR A 176LEU A 284 | NoneNoneNonePUT A 401 (-3.7A)None | 1.06A | 2bdmA-1jl0A:0.0 | 2bdmA-1jl0A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7j | PROTEIN YCIO (Escherichiacoli) |
PF01300(Sua5_yciO_yrdC) | 5 | LEU A 136LEU A 133LEU A 67THR A 66LEU A 141 | NoneNoneNoneSO4 A 207 (-4.7A)None | 0.97A | 2bdmA-1k7jA:0.0 | 2bdmA-1k7jA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd1 | PROTEIN TRANSPORTPROTEIN SEC24 (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | LEU A 871LEU A 808LEU A 859ILE A 856LEU A 759 | None | 0.97A | 2bdmA-1pd1A:undetectable | 2bdmA-1pd1A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qh4 | CREATINE KINASE (Gallus gallus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | LEU A 162LEU A 165ILE A 260THR A 224LEU A 226 | None | 1.06A | 2bdmA-1qh4A:undetectable | 2bdmA-1qh4A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qju | PROTEIN VP1 (Rhinovirus A) |
PF00073(Rhv) | 5 | LEU 1 181ILE 1 122ILE 1 236LEU 1 217THR 1 216 | W01 17001 (-4.6A)W01 17001 ( 4.6A)W01 17001 ( 4.9A)W01 17001 (-4.2A)None | 1.02A | 2bdmA-1qju1:undetectable | 2bdmA-1qju1:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tki | TITIN (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 150LEU A 209THR A 208LEU A 206SER A 205 | None | 1.05A | 2bdmA-1tkiA:undetectable | 2bdmA-1tkiA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wy8 | NP95-LIKE RINGFINGER PROTEIN,ISOFORM A (Homo sapiens) |
PF00240(ubiquitin) | 5 | LEU A 52ILE A 76ILE A 10LEU A 65THR A 64 | None | 1.02A | 2bdmA-1wy8A:undetectable | 2bdmA-1wy8A:11.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyd | HYPOTHETICALASPARTYL-TRNASYNTHETASE (Sulfurisphaeratokodaii) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 5 | LEU A 242ILE A 245ILE A 249LEU A 404LEU A 401 | None | 0.80A | 2bdmA-1wydA:undetectable | 2bdmA-1wydA:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a0s | 6-PYRUVOYLTETRAHYDROPTERINSYNTHASE (Plasmodiumvivax) |
PF01242(PTPS) | 5 | LEU A 154LEU A 151ILE A 180LEU A 142LEU A 145 | None | 1.07A | 2bdmA-2a0sA:undetectable | 2bdmA-2a0sA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4y | FLAGELLARHOOK-ASSOCIATEDPROTEIN 1 (Salmonellaenterica) |
no annotation | 6 | ILE A 133ILE A 433LEU A 119THR A 118LEU A 116PHE A 112 | None | 0.92A | 2bdmA-2d4yA:0.6 | 2bdmA-2d4yA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4y | FLAGELLARHOOK-ASSOCIATEDPROTEIN 1 (Salmonellaenterica) |
no annotation | 6 | ILE A 133ILE A 433LEU A 119THR A 118LEU A 116SER A 115 | None | 0.98A | 2bdmA-2d4yA:0.6 | 2bdmA-2d4yA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4y | FLAGELLARHOOK-ASSOCIATEDPROTEIN 1 (Salmonellaenterica) |
no annotation | 5 | PHE A 326ILE A 433LEU A 119THR A 118LEU A 116 | None | 1.01A | 2bdmA-2d4yA:0.6 | 2bdmA-2d4yA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i79 | ACETYLTRANSFERASE,GNAT FAMILY (Streptococcuspneumoniae) |
PF00583(Acetyltransf_1) | 5 | LEU A 121LEU A 124LEU A 90ILE A 76ILE A 60 | None | 1.06A | 2bdmA-2i79A:undetectable | 2bdmA-2i79A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2z | HYPOTHETICAL PROTEIN (Bacillushalodurans) |
PF01933(UPF0052) | 5 | LEU A 132ILE A 148ILE A 155LEU A 188SER A 187 | NoneNoneNoneNoneSO4 A 324 ( 3.5A) | 0.86A | 2bdmA-2o2zA:undetectable | 2bdmA-2o2zA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odh | R.BCNI (Brevibacilluscentrosporus) |
PF15515(MvaI_BcnI) | 5 | LEU A 75ILE A 153ILE A 185THR A 189LEU A 191 | None | 1.03A | 2bdmA-2odhA:undetectable | 2bdmA-2odhA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pmt | GLUTATHIONETRANSFERASE (Proteusmirabilis) |
PF00043(GST_C)PF02798(GST_N) | 5 | LEU A 18LEU A 23LEU A 76ASN A 59LEU A 57 | None | 1.08A | 2bdmA-2pmtA:3.2 | 2bdmA-2pmtA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pts | ADENYLOSUCCINATELYASE (Escherichiacoli) |
PF00206(Lyase_1)PF08328(ASL_C) | 5 | LEU A 135ILE A 350ASN A 318LEU A 321LEU A 324 | None | 0.96A | 2bdmA-2ptsA:1.9 | 2bdmA-2ptsA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pts | ADENYLOSUCCINATELYASE (Escherichiacoli) |
PF00206(Lyase_1)PF08328(ASL_C) | 6 | PHE A 27LEU A 198ILE A 143ILE A 350ASN A 318LEU A 321 | None | 1.15A | 2bdmA-2ptsA:1.9 | 2bdmA-2ptsA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qkd | ZINC FINGER PROTEINZPR1 (Mus musculus) |
PF03367(zf-ZPR1) | 5 | LEU A 391ILE A 394LEU A 354THR A 353LEU A 357 | None | 0.90A | 2bdmA-2qkdA:undetectable | 2bdmA-2qkdA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w5s | PROCESSED GLYCEROLPHOSPHATELIPOTEICHOIC ACIDSYNTHASE (Staphylococcusaureus) |
PF00884(Sulfatase) | 5 | PHE A 285LEU A 452LEU A 410ILE A 252ILE A 470 | None | 0.89A | 2bdmA-2w5sA:undetectable | 2bdmA-2w5sA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnt | RIBOSOMAL PROTEIN S6KINASE (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 497LEU A 498LEU A 502ILE A 501LEU A 604 | None | 0.95A | 2bdmA-2wntA:undetectable | 2bdmA-2wntA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xa7 | ADAPTOR-RELATEDPROTEIN COMPLEX 2,ALPHA 2 SUBUNIT (Rattusnorvegicus) |
PF01602(Adaptin_N) | 5 | PHE A 97ILE A 72ASN A 34LEU A 37PHE A 44 | None | 0.97A | 2bdmA-2xa7A:undetectable | 2bdmA-2xa7A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xka | FTSZ/TUBULIN-RELATEDPROTEIN (Bacillusthuringiensis) |
PF00091(Tubulin) | 5 | LEU A 274LEU A 270ILE A 23ILE A 21THR A 247 | None | 0.91A | 2bdmA-2xkaA:undetectable | 2bdmA-2xkaA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yv7 | CG10997-PA (Drosophilamelanogaster) |
no annotation | 5 | LEU A 204LEU A 201ILE A 197ILE A 185LEU A 147 | None | 1.05A | 2bdmA-2yv7A:undetectable | 2bdmA-2yv7A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zyz | PUTATIVEUNCHARACTERIZEDPROTEIN PAE0789TRNA-SPLICINGENDONUCLEASE (Pyrobaculumaerophilum) |
PF01974(tRNA_int_endo)PF02778(tRNA_int_endo_N)no annotation | 5 | LEU A 68ILE B 142LEU B 163THR B 162LEU B 176 | None | 0.83A | 2bdmA-2zyzA:undetectable | 2bdmA-2zyzA:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahr | ERO1-LIKE PROTEINALPHA (Homo sapiens) |
PF04137(ERO1) | 5 | LEU A 65LEU A 68LEU A 344ILE A 347ILE A 351 | None | 1.01A | 2bdmA-3ahrA:undetectable | 2bdmA-3ahrA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bbh | RIBOSOME BIOGENESISPROTEIN NEP1-LIKE (Methanocaldococcusjannaschii) |
PF03587(EMG1) | 5 | ILE A 138ILE A 160LEU A 126THR A 125LEU A 129 | None | 0.98A | 2bdmA-3bbhA:undetectable | 2bdmA-3bbhA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bit | FACT COMPLEX SUBUNITSPT16 (Saccharomycescerevisiae) |
PF00557(Peptidase_M24)PF14826(FACT-Spt16_Nlob) | 5 | LEU A 84LEU A 4ASN A 296LEU A 55PHE A 11 | None | 1.07A | 2bdmA-3bitA:undetectable | 2bdmA-3bitA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ek1 | ALDEHYDEDEHYDROGENASE (Brucellaabortus) |
PF00171(Aldedh) | 5 | LEU A 4LEU A 2LEU A 188THR A 189LEU A 191 | None | 0.84A | 2bdmA-3ek1A:undetectable | 2bdmA-3ek1A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ep7 | S-ADENOSYLMETHIONINEDECARBOXYLASE ALPHACHAIN (Homo sapiens) |
PF01536(SAM_decarbox) | 5 | LEU A 180ILE A 268LEU A 177THR A 176LEU A 284 | None | 1.07A | 2bdmA-3ep7A:undetectable | 2bdmA-3ep7A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fb4 | ADENYLATE KINASE (Jeotgalibacillusmarinus) |
PF00406(ADK)PF05191(ADK_lid) | 5 | ILE A 26ILE A 3ASN A 209LEU A 212LEU A 215 | None | 0.91A | 2bdmA-3fb4A:undetectable | 2bdmA-3fb4A:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hxs | THIOREDOXIN (Bacteroidesfragilis) |
PF00085(Thioredoxin) | 5 | LEU A 138LEU A 139ILE A 84ILE A 86LEU A 130 | None | 0.99A | 2bdmA-3hxsA:undetectable | 2bdmA-3hxsA:14.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2j | PROTEIN POLYBROMO-1 (Homo sapiens) |
PF00439(Bromodomain) | 5 | PHE A 424LEU A 398LEU A 405ILE A 401LEU A 357 | None | 1.07A | 2bdmA-3k2jA:undetectable | 2bdmA-3k2jA:12.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mcx | SUSD SUPERFAMILYPROTEIN (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | LEU A 423LEU A 427ILE A 426ASN A 234LEU A 233 | None | 0.91A | 2bdmA-3mcxA:0.6 | 2bdmA-3mcxA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ni8 | PFC0360W PROTEIN (Plasmodiumfalciparum) |
PF08327(AHSA1) | 5 | ILE A 70LEU A 44THR A 45LEU A 47SER A 48 | NoneIPA A 159 ( 4.7A)NoneNoneNone | 0.98A | 2bdmA-3ni8A:undetectable | 2bdmA-3ni8A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oc6 | 6-PHOSPHOGLUCONOLACTONASE (Mycolicibacteriumsmegmatis) |
PF01182(Glucosamine_iso) | 5 | LEU A 92LEU A 93ILE A 96ILE A 61THR A 38 | None | 1.01A | 2bdmA-3oc6A:undetectable | 2bdmA-3oc6A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sze | SERINE PROTEASE ESPP (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | LEU A 639ILE A 556ASN A 515LEU A 544PHE A 646 | None | 1.05A | 2bdmA-3szeA:undetectable | 2bdmA-3szeA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tvi | ASPARTOKINASE (Clostridiumacetobutylicum) |
PF00696(AA_kinase)PF01842(ACT) | 5 | ILE A 407ASN A 391THR A 395LEU A 397SER A 398 | None | 0.59A | 2bdmA-3tviA:2.1 | 2bdmA-3tviA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgo | E3 UBIQUITIN-PROTEINLIGASE CBL-B (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 5 | LEU A 78LEU A 143THR A 144LEU A 146PHE A 150 | None | 0.89A | 2bdmA-3vgoA:undetectable | 2bdmA-3vgoA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbk | EUKARYOTICTRANSLATIONINITIATION FACTOR 5B (Saccharomycescerevisiae) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF11987(IF-2) | 5 | LEU A 592LEU A 575ILE A 572LEU A 566SER A 565 | None | 0.92A | 2bdmA-3wbkA:undetectable | 2bdmA-3wbkA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpp | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 5 | LEU A 517LEU A 510ILE A 533ASN A 494THR A 492 | None | 1.02A | 2bdmA-3zppA:undetectable | 2bdmA-3zppA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b18 | IMPORTIN SUBUNITALPHA-1 (Homo sapiens) |
PF00514(Arm)PF16186(Arm_3) | 5 | LEU A 305LEU A 317ILE A 362LEU A 347LEU A 344 | None | 1.05A | 2bdmA-4b18A:undetectable | 2bdmA-4b18A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b4d | FERREDOXIN-NADPREDUCTASE (Xanthomonascitri) |
PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | LEU A 205ILE A 140LEU A 192THR A 193LEU A 195 | NoneNoneNone CL A1261 (-4.0A)None | 0.73A | 2bdmA-4b4dA:undetectable | 2bdmA-4b4dA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8c | GLUCOSE-REPRESSIBLEALCOHOLDEHYDROGENASETRANSCRIPTIONALEFFECTOR (Saccharomycescerevisiae) |
PF03372(Exo_endo_phos)PF13855(LRR_8) | 5 | LEU D 399LEU D 379ILE D 376LEU D 364PHE D 408 | None | 0.97A | 2bdmA-4b8cD:undetectable | 2bdmA-4b8cD:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8j | IMPORTIN SUBUNITALPHA-1A (Oryza sativa) |
PF00514(Arm)PF01749(IBB)PF16186(Arm_3) | 5 | LEU A 293LEU A 305ILE A 351LEU A 335LEU A 332 | None | 1.01A | 2bdmA-4b8jA:undetectable | 2bdmA-4b8jA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bpl | IMPORTIN SUBUNITALPHA-1A (Oryza sativa) |
PF00514(Arm)PF16186(Arm_3) | 5 | LEU A 293LEU A 305ILE A 351LEU A 335LEU A 332 | None | 0.95A | 2bdmA-4bplA:undetectable | 2bdmA-4bplA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4efh | ACTIN-1 (Acanthamoebacastellanii) |
PF00022(Actin) | 5 | LEU A 242ILE A 208ILE A 212LEU A 193THR A 194 | None | 0.93A | 2bdmA-4efhA:undetectable | 2bdmA-4efhA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eku | PROTEIN-TYROSINEKINASE 2-BETA (Homo sapiens) |
PF00373(FERM_M) | 5 | LEU A 299LEU A 279ILE A 286ILE A 348LEU A 320 | None | 1.06A | 2bdmA-4ekuA:undetectable | 2bdmA-4ekuA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gha | POLYMERASE COFACTORVP35 (Marburgmarburgvirus) |
PF02097(Filo_VP35) | 5 | LEU A 266THR A 267LEU A 269SER A 270PHE A 276 | None G J 12 ( 3.4A)NoneNoneNone | 0.83A | 2bdmA-4ghaA:undetectable | 2bdmA-4ghaA:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gvl | TRKA DOMAIN PROTEIN (Geobactersulfurreducens) |
PF02080(TrkA_C)PF02254(TrkA_N) | 5 | LEU A 323ILE A 292ILE A 297LEU A 331LEU A 280 | None | 1.00A | 2bdmA-4gvlA:undetectable | 2bdmA-4gvlA:24.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M) | 5 | PHE M 194LEU M 260LEU M 261ILE M 246LEU M 465 | None | 1.05A | 2bdmA-4heaM:0.7 | 2bdmA-4heaM:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j1s | POLYKETIDE SYNTHASEPKSJ (Bacillussubtilis) |
PF08659(KR) | 5 | LEU A 82LEU A 119ILE A 87ILE A 27LEU A 74 | None | 0.86A | 2bdmA-4j1sA:undetectable | 2bdmA-4j1sA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l8p | BILE ACID7A-DEHYDRATASE, BAIE ([Clostridium]hiranonis) |
PF13577(SnoaL_4) | 5 | LEU A 26ILE A 139LEU A 42LEU A 34PHE A 31 | None1PE A 204 ( 4.6A)NoneNoneNone | 1.03A | 2bdmA-4l8pA:undetectable | 2bdmA-4l8pA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5p | NADPH DEHYDROGENASE (Scheffersomycesstipitis) |
PF00724(Oxidored_FMN) | 5 | LEU A 199LEU A 222ILE A 221ILE A 239PHE A 263 | None | 1.00A | 2bdmA-4m5pA:undetectable | 2bdmA-4m5pA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7e | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 421LEU A 423THR A 386LEU A 388SER A 389 | None | 1.02A | 2bdmA-4m7eA:undetectable | 2bdmA-4m7eA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7e | PROTEINBRASSINOSTEROIDINSENSITIVE 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF12799(LRR_4)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 423LEU A 385THR A 386LEU A 388SER A 389 | None | 1.05A | 2bdmA-4m7eA:undetectable | 2bdmA-4m7eA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mag | SIALIC ACID BINDINGPROTEIN (Vibrio cholerae) |
PF03480(DctP) | 5 | ILE A 231ILE A 232LEU A 4THR A 3LEU A 37 | None | 1.07A | 2bdmA-4magA:undetectable | 2bdmA-4magA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6f | PUTATIVE THIOSUGARSYNTHASE (Amycolatopsisorientalis) |
PF05690(ThiG) | 5 | LEU A 43ILE A 30ILE A 52LEU A 215THR A 214 | None | 0.96A | 2bdmA-4n6fA:undetectable | 2bdmA-4n6fA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rt6 | HEME/HEMOPEXIN-BINDING PROTEIN (Haemophilusinfluenzae) |
PF05860(Haemagg_act) | 5 | LEU A 255ILE A 279ILE A 301ASN A 365LEU A 361 | None | 1.01A | 2bdmA-4rt6A:undetectable | 2bdmA-4rt6A:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uad | IMPORTIN SUBUNITALPHA-7 (Homo sapiens) |
PF00514(Arm)PF16186(Arm_3) | 5 | LEU A 303LEU A 315ILE A 360LEU A 345LEU A 342 | None | 1.04A | 2bdmA-4uadA:undetectable | 2bdmA-4uadA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 5 | LEU A 738LEU A 740ILE A 817LEU A 800PHE A 793 | None | 0.97A | 2bdmA-4wd9A:1.8 | 2bdmA-4wd9A:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y68 | PUTATIVENISIN-RESISTANCEPROTEIN (Streptococcusagalactiae) |
no annotation | 5 | LEU C 313LEU C 122ILE C 126THR C 130LEU C 163 | None | 0.99A | 2bdmA-4y68C:undetectable | 2bdmA-4y68C:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z7x | MDBA (Actinomycesoris) |
PF13462(Thioredoxin_4) | 5 | LEU A 164LEU A 131LEU A 289ILE A 153THR A 270 | None | 0.95A | 2bdmA-4z7xA:undetectable | 2bdmA-4z7xA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxi | TYROCIDINESYNTHETASE 3 (Acinetobacterbaumannii) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 5 | PHE A 424ILE A 401LEU A 265LEU A 268SER A 269 | None | 0.90A | 2bdmA-4zxiA:undetectable | 2bdmA-4zxiA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a1n | AMINOACYL TRNASYNTHASECOMPLEX-INTERACTINGMULTIFUNCTIONALPROTEIN 2 (Homo sapiens) |
PF00043(GST_C) | 5 | PHE B 199LEU B 112LEU B 108ILE B 122LEU B 217 | None | 1.02A | 2bdmA-5a1nB:undetectable | 2bdmA-5a1nB:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5axi | E3 UBIQUITIN-PROTEINLIGASE CBL-B (Mus musculus) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 5 | LEU A 78LEU A 143THR A 144LEU A 146PHE A 150 | None | 0.72A | 2bdmA-5axiA:undetectable | 2bdmA-5axiA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5axi | E3 UBIQUITIN-PROTEINLIGASE CBL-B (Mus musculus) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 5 | LEU A 78THR A 144LEU A 146SER A 147PHE A 150 | None | 0.77A | 2bdmA-5axiA:undetectable | 2bdmA-5axiA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bsz | N-METHYLTRANSFERASE (Streptoalloteichussp. ATCC 53650) |
PF13649(Methyltransf_25) | 5 | LEU A 218LEU A 215LEU A 228THR A 229LEU A 238 | None | 0.97A | 2bdmA-5bszA:undetectable | 2bdmA-5bszA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bvr | ALPHA-ACTININ-LIKEPROTEIN 1 (Schizosaccharomycespombe) |
PF00307(CH) | 5 | LEU A 37LEU A 99ILE A 102THR A 13PHE A 18 | None | 0.99A | 2bdmA-5bvrA:0.9 | 2bdmA-5bvrA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c30 | RYANODINE RECEPTOR 1 (Oryctolaguscuniculus) |
PF02026(RyR) | 5 | LEU A 874ILE A 870LEU A 932THR A 931LEU A 933 | None | 1.07A | 2bdmA-5c30A:undetectable | 2bdmA-5c30A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cth | BIDIRECTIONAL SUGARTRANSPORTER SWEET2B (Oryza sativa) |
PF03083(MtN3_slv) | 5 | LEU A 49LEU A 52LEU A 85ILE A 88ILE A 92 | None | 0.67A | 2bdmA-5cthA:undetectable | 2bdmA-5cthA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d0f | UNCHARACTERIZEDPROTEIN ([Candida]glabrata) |
PF06202(GDE_C)PF14699(hGDE_N)PF14701(hDGE_amylase)PF14702(hGDE_central) | 5 | LEU A 684ILE A 860ILE A 862LEU A 734THR A 733 | None | 0.61A | 2bdmA-5d0fA:1.6 | 2bdmA-5d0fA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dm4 | METHYLTRANSFERASEDOMAIN FAMILY (Bacilluspumilus) |
PF13489(Methyltransf_23) | 5 | ILE A 155ILE A 157LEU A 198THR A 199LEU A 197 | None | 1.05A | 2bdmA-5dm4A:undetectable | 2bdmA-5dm4A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4v | NUCLEOPROTEIN,PHOSPHOPROTEIN (Measlesmorbillivirus) |
PF00973(Paramyxo_ncap)PF13825(Paramyxo_PNT) | 5 | LEU A 33LEU A 148ILE A 151ILE A 155LEU A 58 | None | 0.86A | 2bdmA-5e4vA:0.8 | 2bdmA-5e4vA:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fby | CLEAVED PEPTIDESEPARASE (Chaetomiumthermophilum;syntheticconstruct) |
PF03568(Peptidase_C50)no annotation | 5 | LEU B 13LEU A1699ILE A1702ILE A1707SER A1718 | None | 0.66A | 2bdmA-5fbyB:undetectable | 2bdmA-5fbyB:5.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gxu | NADPH--CYTOCHROMEP450 REDUCTASE 2 (Arabidopsisthaliana) |
PF00175(NAD_binding_1)PF00258(Flavodoxin_1)PF00667(FAD_binding_1) | 5 | LEU A 231LEU A 258LEU A 262ILE A 261THR A 106 | None | 1.07A | 2bdmA-5gxuA:3.2 | 2bdmA-5gxuA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h8w | ATP-DEPENDENT DNAHELICASE TA0057 (Thermoplasmaacidophilum) |
PF06733(DEAD_2)PF06777(HBB)PF13307(Helicase_C_2) | 5 | PHE A 397LEU A 210LEU A 57LEU A 55ILE A 208 | None | 1.06A | 2bdmA-5h8wA:undetectable | 2bdmA-5h8wA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijj | SPX DOMAIN (Chaetomiumthermophilum) |
PF03105(SPX) | 5 | LEU A 105LEU A 102ILE A 166ILE A 162THR A 82 | None | 1.04A | 2bdmA-5ijjA:undetectable | 2bdmA-5ijjA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip7 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB3 (Saccharomycescerevisiae) |
PF01000(RNA_pol_A_bac)PF01193(RNA_pol_L) | 5 | LEU C 72ILE C 70ILE C 144LEU C 101THR C 100 | None | 1.07A | 2bdmA-5ip7C:undetectable | 2bdmA-5ip7C:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mrw | POTASSIUM-TRANSPORTING ATPASEPOTASSIUM-BINDINGSUBUNIT (Escherichiacoli) |
PF03814(KdpA) | 5 | LEU A 380ILE A 148ILE A 145LEU A 27LEU A 30 | None | 0.98A | 2bdmA-5mrwA:undetectable | 2bdmA-5mrwA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd7 | KINESIN-LIKE PROTEINKIF20A (Mus musculus) |
PF00225(Kinesin) | 5 | PHE C 305LEU C 408ILE C 307LEU C 463THR C 464 | None | 1.00A | 2bdmA-5nd7C:undetectable | 2bdmA-5nd7C:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0x | PUTATIVE FERRICREDUCTASE (Cylindrospermumstagnale) |
PF08022(FAD_binding_8)PF08030(NAD_binding_6) | 5 | LEU A 596LEU A 563ILE A 550ILE A 546LEU A 533 | None | 1.06A | 2bdmA-5o0xA:undetectable | 2bdmA-5o0xA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5txv | ATP-DEPENDENTPROTEASE ATPASESUBUNIT HSLU (Escherichiacoli) |
PF00004(AAA)PF07724(AAA_2)PF10431(ClpB_D2-small) | 5 | LEU A 399LEU A 402ILE A 376ILE A 373THR A 419 | None | 0.90A | 2bdmA-5txvA:undetectable | 2bdmA-5txvA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vem | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 5 (Homo sapiens) |
PF01663(Phosphodiest) | 5 | PHE A 359LEU A 182LEU A 184ILE A 234LEU A 373 | None | 1.05A | 2bdmA-5vemA:undetectable | 2bdmA-5vemA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vqi | IMPORTIN SUBUNITALPHA (Neurosporacrassa) |
no annotation | 5 | LEU B 302LEU B 314ILE B 359LEU B 344LEU B 341 | None | 1.05A | 2bdmA-5vqiB:undetectable | 2bdmA-5vqiB:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbl | REGULATORY-ASSOCIATED PROTEIN OF TOR 1 (Arabidopsisthaliana) |
no annotation | 5 | LEU A 485LEU A 482LEU A 523ILE A 526ILE A 530 | None | 0.72A | 2bdmA-5wblA:undetectable | 2bdmA-5wblA:10.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xbk | IMPORTIN-4 (Homo sapiens) |
no annotation | 5 | LEU D 989LEU D 986LEU D1023ILE D1026ILE D1030 | None | 0.94A | 2bdmA-5xbkD:undetectable | 2bdmA-5xbkD:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9w | POLLEN RECEPTOR-LIKEKINASE 6 (Arabidopsisthaliana) |
no annotation | 5 | LEU B 194LEU B 173ILE B 212ASN B 225LEU B 222 | None | 1.05A | 2bdmA-5y9wB:undetectable | 2bdmA-5y9wB:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yim | SDEA (Legionellapneumophila) |
no annotation | 5 | LEU A 708LEU A 747ILE A 740LEU A 663THR A 662 | None | 0.97A | 2bdmA-5yimA:undetectable | 2bdmA-5yimA:11.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cf8 | LYTICTRANSGLYCOSYLASE (Campylobacterjejuni) |
no annotation | 5 | LEU A 116LEU A 135THR A 136LEU A 138PHE A 142 | NoneSO4 A 704 (-4.5A)NoneNoneNone | 0.77A | 2bdmA-6cf8A:undetectable | 2bdmA-6cf8A:10.49 |