SIMILAR PATTERNS OF AMINO ACIDS FOR 2BDM_A_TMIA501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eu1 DIMETHYL SULFOXIDE
REDUCTASE

(Rhodobacter
sphaeroides) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 LEU A  42
PHE A  29
GLY A  44
THR A 655
 None
 1.09A 2bdmA-1eu1A:
undetectable		 2bdmA-1eu1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fzq ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
3

(Mus musculus) 		PF00025
(Arf) 		4 SER A  94
PHE A 100
GLY A 104
ILE A 148
 None
 1.06A 2bdmA-1fzqA:
undetectable		 2bdmA-1fzqA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gco GLUCOSE
DEHYDROGENASE

(Bacillus
megaterium) 		PF13561
(adh_short_C2) 		4 SER A 101
MET A 104
LEU A 154
ILE A 195
 None
None
None
NAD  A 601 (-3.8A)
 1.09A 2bdmA-1gcoA:
undetectable		 2bdmA-1gcoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1li7 CYSTEINYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF01406
(tRNA-synt_1e)
PF09190
(DALR_2) 		4 SER A 300
LEU A 302
GLY A  39
ILE A 105
 None
 0.71A 2bdmA-1li7A:
undetectable		 2bdmA-1li7A:
21.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nr6 CYTOCHROME P450 2C5

(Oryctolagus
cuniculus) 		PF00067
(p450) 		4 LEU A 291
PHE A 292
GLY A 295
THR A 299
 HEM  A 500 (-4.4A)
None
HEM  A 500 (-3.2A)
HEM  A 500 ( 4.3A)
 0.50A 2bdmA-1nr6A:
39.3		 2bdmA-1nr6A:
53.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		4 LEU A 239
GLY A  10
THR A   8
ILE A 191
 None
 0.94A 2bdmA-1r6aA:
undetectable		 2bdmA-1r6aA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vj7 BIFUNCTIONAL
RELA/SPOT

(Streptococcus
dysgalactiae) 		PF04607
(RelA_SpoT)
PF13328
(HD_4) 		4 LEU A 234
PHE A 235
GLY A 236
ILE A 268
 None
 0.91A 2bdmA-1vj7A:
undetectable		 2bdmA-1vj7A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy0 GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00348
(polyprenyl_synt) 		4 SER A  82
LEU A 181
GLY A 179
ILE A 337
 None
 0.93A 2bdmA-1wy0A:
undetectable		 2bdmA-1wy0A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr4 PUTATIVE CITRATE
LYASE ALPHA
CHAIN/CITRATE-ACP
TRANSFERASE

(Salmonella
enterica) 		PF04223
(CitF) 		4 LEU A 460
GLY A 439
THR A 436
ILE A 370
 None
 1.02A 2bdmA-1xr4A:
undetectable		 2bdmA-1xr4A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yis ADENYLOSUCCINATE
LYASE

(Caenorhabditis
elegans) 		PF00206
(Lyase_1) 		4 LEU A 143
GLY A 165
THR A 163
ILE A 441
 None
 1.06A 2bdmA-1yisA:
undetectable		 2bdmA-1yisA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2afh NITROGENASE
MOLYBDENUM-IRON
PROTEIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 SER B 255
PHE B 201
GLY B 203
ILE B 166
 None
 1.03A 2bdmA-2afhB:
undetectable		 2bdmA-2afhB:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2x ANTIBODY AQC2 FAB
INTEGRIN ALPHA-1

(Mus musculus;
Rattus
norvegicus) 		PF00092
(VWA)
PF07654
(C1-set)
PF07686
(V-set) 		4 SER L  91
GLY A 258
THR A 256
ILE A 306
 None
MG  A 400 ( 4.4A)
None
None
 0.99A 2bdmA-2b2xL:
undetectable		 2bdmA-2b2xL:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b4g DIHYDROOROTATE
DEHYDROGENASE

(Trypanosoma
brucei) 		PF01180
(DHO_dh) 		4 SER A  45
LEU A  72
GLY A  53
ILE A 212
 FMN  A1400 (-2.8A)
ORO  A1399 (-4.1A)
None
None
 1.03A 2bdmA-2b4gA:
undetectable		 2bdmA-2b4gA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvt BETA-1,4-MANNANASE

(Cellulomonas
fimi) 		PF02156
(Glyco_hydro_26) 		4 SER A  54
PHE A  63
GLY A 106
ILE A 168
 None
 0.86A 2bdmA-2bvtA:
undetectable		 2bdmA-2bvtA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bx7 DIHYDROOROTATE
DEHYDROGENASE

(Lactococcus
lactis) 		PF01180
(DHO_dh) 		4 SER A  44
LEU A  71
GLY A  52
ILE A 210
 FMN  A1312 (-2.6A)
ACT  A1313 ( 4.7A)
None
None
 0.99A 2bdmA-2bx7A:
undetectable		 2bdmA-2bx7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT

(Gallus gallus) 		PF00079
(Serpin) 		4 MET A  54
LEU A  44
GLY A 333
THR A 335
 None
 1.11A 2bdmA-2dutA:
undetectable		 2bdmA-2dutA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dut HETEROCHROMATIN-ASSO
CIATED PROTEIN MENT

(Gallus gallus) 		PF00079
(Serpin) 		4 SER A   7
LEU A  58
THR A 315
ILE A 310
 None
 1.01A 2bdmA-2dutA:
undetectable		 2bdmA-2dutA:
21.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f9q CYTOCHROME P450 2D6

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 302
PHE A 303
GLY A 306
THR A 310
 HEM  A 600 ( 4.5A)
None
HEM  A 600 (-3.1A)
HEM  A 600 (-4.0A)
 0.58A 2bdmA-2f9qA:
37.0		 2bdmA-2f9qA:
45.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f9q CYTOCHROME P450 2D6

(Homo sapiens) 		PF00067
(p450) 		4 SER A 135
LEU A 302
GLY A 306
THR A 309
 None
HEM  A 600 ( 4.5A)
HEM  A 600 (-3.1A)
HEM  A 600 (-3.5A)
 1.12A 2bdmA-2f9qA:
37.0		 2bdmA-2f9qA:
45.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqx MEMBRANE LIPOPROTEIN
TMPC

(Treponema
pallidum) 		PF02608
(Bmp) 		4 LEU A 160
PHE A 161
GLY A 164
ILE A 322
 None
GMP  A 400 ( 4.8A)
None
None
 0.82A 2bdmA-2fqxA:
undetectable		 2bdmA-2fqxA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iod DIHYDROFLAVONOL
4-REDUCTASE

(Vitis vinifera) 		PF01370
(Epimerase) 		4 PHE A 312
GLY A 314
THR A 318
ILE A 198
 None
 0.95A 2bdmA-2iodA:
undetectable		 2bdmA-2iodA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jif SHORT/BRANCHED CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE

(Homo sapiens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LEU A  97
PHE A  98
GLY A 101
THR A 114
 None
 1.00A 2bdmA-2jifA:
undetectable		 2bdmA-2jifA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mn2 YMOB

(Yersinia
enterocolitica) 		PF10757
(YbaJ) 		4 SER A  89
LEU A  86
GLY A  25
ILE A  55
 None
 1.06A 2bdmA-2mn2A:
undetectable		 2bdmA-2mn2A:
14.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2nnj CYTOCHROME P450 2C8

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 294
PHE A 295
GLY A 298
THR A 302
 HEM  A 500 ( 4.3A)
None
HEM  A 500 (-3.4A)
HEM  A 500 (-4.2A)
 0.49A 2bdmA-2nnjA:
39.7		 2bdmA-2nnjA:
55.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pg6 CYTOCHROME P450 2A6

(Homo sapiens) 		PF00067
(p450) 		5 SER A 131
LEU A 298
GLY A 302
THR A 305
ILE A 366
 None
None
HEM  A 500 (-3.5A)
HEM  A 500 (-3.6A)
HEM  A 500 ( 4.1A)
 1.32A 2bdmA-2pg6A:
39.0		 2bdmA-2pg6A:
55.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2poz PUTATIVE DEHYDRATASE

(Mesorhizobium
japonicum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 MET A 288
LEU A 115
PHE A 116
GLY A 117
 None
 0.89A 2bdmA-2pozA:
undetectable		 2bdmA-2pozA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v0j BIFUNCTIONAL PROTEIN
GLMU

(Haemophilus
influenzae) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		4 SER A  21
MET A  19
GLY A  14
ILE A  10
 None
None
H2U  A1453 ( 3.4A)
None
 1.09A 2bdmA-2v0jA:
undetectable		 2bdmA-2v0jA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vfw SHORT-CHAIN
Z-ISOPRENYL
DIPHOSPHATE
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF01255
(Prenyltransf) 		4 SER A 226
LEU A 223
GLY A 159
THR A  87
 None
 1.10A 2bdmA-2vfwA:
undetectable		 2bdmA-2vfwA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zal L-ASPARAGINASE

(Escherichia
coli) 		PF01112
(Asparaginase_2) 		4 SER B 211
GLY B 275
THR B 292
ILE A  15
 ASP  B 501 ( 3.8A)
None
None
None
 1.06A 2bdmA-2zalB:
undetectable		 2bdmA-2zalB:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zt9 CYTOCHROME B6-F
COMPLEX SUBUNIT 4
CYTOCHROME B6-F
COMPLEX SUBUNIT 5
CYTOCHROME B6-F
COMPLEX SUBUNIT 7

(Nostoc sp. PCC
7120) 		PF00032
(Cytochrom_B_C)
PF02529
(PetG)
PF08041
(PetM) 		4 LEU F  10
PHE F  13
GLY G  12
ILE B 145
 None
 0.92A 2bdmA-2zt9F:
undetectable		 2bdmA-2zt9F:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Bifidobacterium
longum) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		4 SER A 489
MET A 487
GLY A 543
THR A 805
 None
 1.04A 2bdmA-2zxqA:
undetectable		 2bdmA-2zxqA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahx BETA-GLUCOSIDASE A

(Clostridium
cellulovorans) 		PF00232
(Glyco_hydro_1) 		4 LEU A 150
PHE A 151
GLY A 155
ILE A 109
 None
 0.99A 2bdmA-3ahxA:
undetectable		 2bdmA-3ahxA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b4w ALDEHYDE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00171
(Aldedh) 		4 MET A 108
GLY A 280
THR A 292
ILE A 388
 GOL  A 602 ( 4.9A)
None
None
None
 0.90A 2bdmA-3b4wA:
undetectable		 2bdmA-3b4wA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2b TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Agrobacterium
fabrum) 		PF00440
(TetR_N) 		4 SER A 165
LEU A 202
PHE A 199
GLY A 204
 None
 0.93A 2bdmA-3c2bA:
undetectable		 2bdmA-3c2bA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctt MALTASE-GLUCOAMYLASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 LEU A 499
GLY A 501
THR A 525
ILE A 565
 None
 0.80A 2bdmA-3cttA:
undetectable		 2bdmA-3cttA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctz XAA-PRO
AMINOPEPTIDASE 1

(Homo sapiens) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
PF16188
(Peptidase_M24_C)
PF16189
(Creatinase_N_2) 		4 SER A 479
LEU A 476
GLY A 450
ILE A 567
 None
 0.99A 2bdmA-3ctzA:
undetectable		 2bdmA-3ctzA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3y UNCHARACTERIZED
PROTEIN

(Enterococcus
faecalis) 		PF05193
(Peptidase_M16_C) 		4 PHE A 279
GLY A 277
THR A 350
ILE A 392
 None
 1.11A 2bdmA-3d3yA:
undetectable		 2bdmA-3d3yA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gip N-ACYL-D-GLUTAMATE
DEACYLASE

(Bordetella
bronchiseptica) 		PF07969
(Amidohydro_3) 		4 LEU A 377
GLY A 379
THR A 382
ILE A 452
 None
 0.94A 2bdmA-3gipA:
undetectable		 2bdmA-3gipA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3o SHORT CHAIN
DEHYDROGENASE

(Bacillus
anthracis) 		PF13561
(adh_short_C2) 		4 SER A 233
LEU A 230
GLY A  55
ILE A  73
 None
NAE  A 311 (-3.7A)
NAE  A 311 (-3.1A)
None
 0.92A 2bdmA-3i3oA:
undetectable		 2bdmA-3i3oA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifr CARBOHYDRATE KINASE,
FGGY

(Rhodospirillum
rubrum) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 SER A 192
GLY A 186
THR A 140
ILE A 205
 None
 0.98A 2bdmA-3ifrA:
undetectable		 2bdmA-3ifrA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ils AFLATOXIN
BIOSYNTHESIS
POLYKETIDE SYNTHASE

(Aspergillus
parasiticus) 		PF00975
(Thioesterase) 		4 LEU A1871
PHE A1942
GLY A1940
ILE A2100
 None
 1.09A 2bdmA-3ilsA:
undetectable		 2bdmA-3ilsA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixl ARYLMALONATE
DECARBOXYLASE

(Bordetella
bronchiseptica) 		no annotation 4 SER A  71
MET A  11
GLY A 189
ILE A 197
 None
None
PAC  A5000 (-3.7A)
None
 0.80A 2bdmA-3ixlA:
undetectable		 2bdmA-3ixlA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 LEU A 528
GLY A 530
THR A 554
ILE A 594
 None
 0.81A 2bdmA-3lppA:
undetectable		 2bdmA-3lppA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nd0 SLL0855 PROTEIN

(Synechocystis
sp. PCC 6803) 		PF00654
(Voltage_CLC) 		4 MET A 407
LEU A 402
GLY A 191
ILE A 105
 None
 1.08A 2bdmA-3nd0A:
undetectable		 2bdmA-3nd0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pas TETR FAMILY
TRANSCRIPTION
REGULATOR

(Marinobacter
hydrocarbonoclasticus) 		PF00440
(TetR_N)
PF16295
(TetR_C_10) 		4 LEU A 101
PHE A 102
THR A 109
ILE A 118
 None
None
ACT  A 211 ( 4.3A)
None
 0.82A 2bdmA-3pasA:
undetectable		 2bdmA-3pasA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxn KINESIN-LIKE PROTEIN
NOD

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 MET A  97
LEU A 227
GLY A  87
THR A 310
 None
 1.09A 2bdmA-3pxnA:
undetectable		 2bdmA-3pxnA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r92 HEAT SHOCK PROTEIN
HSP 90-ALPHA

(Homo sapiens) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 SER A  52
LEU A  48
GLY A 137
ILE A  26
 06J  A   1 ( 3.7A)
None
None
None
 1.08A 2bdmA-3r92A:
undetectable		 2bdmA-3r92A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ri6 O-ACETYLHOMOSERINE
SULFHYDRYLASE

(Wolinella
succinogenes) 		PF01053
(Cys_Met_Meta_PP) 		5 SER A 213
LEU A 267
GLY A 271
THR A 274
ILE A 392
 None
 1.49A 2bdmA-3ri6A:
undetectable		 2bdmA-3ri6A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ssm METHYLTRANSFERASE

(Micromonospora
griseorubida) 		no annotation 4 LEU A 106
PHE A 110
GLY A 111
THR A 113
 None
 1.01A 2bdmA-3ssmA:
undetectable		 2bdmA-3ssmA:
24.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tk3 CYTOCHROME P450 2B4

(Oryctolagus
cuniculus) 		PF00067
(p450) 		4 LEU A 295
PHE A 296
GLY A 299
THR A 303
 None
None
HEM  A 500 (-3.4A)
HEM  A 500 (-3.3A)
 0.39A 2bdmA-3tk3A:
41.1		 2bdmA-3tk3A:
99.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3top MALTASE-GLUCOAMYLASE
, INTESTINAL

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 LEU A1484
GLY A1486
THR A1509
ILE A1549
 None
 0.95A 2bdmA-3topA:
undetectable		 2bdmA-3topA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty6 ATP-DEPENDENT
PROTEASE SUBUNIT
HSLV

(Bacillus
anthracis) 		PF00227
(Proteasome) 		4 LEU A 137
GLY A 132
THR A 171
ILE A 175
 None
 0.93A 2bdmA-3ty6A:
undetectable		 2bdmA-3ty6A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0a ACYL-COA
THIOESTERASE II
TESB2

(Mycobacterium
marinum) 		PF13622
(4HBT_3) 		4 MET A 102
PHE A 100
GLY A  35
ILE A   3
 None
 1.00A 2bdmA-3u0aA:
undetectable		 2bdmA-3u0aA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3viu PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE 2

(Thermus
thermophilus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 SER A 521
PHE A  82
GLY A 179
ILE A 249
 ADP  A 800 (-4.5A)
None
None
None
 1.01A 2bdmA-3viuA:
undetectable		 2bdmA-3viuA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF01554
(MatE) 		4 SER A 249
GLY A 388
THR A 304
ILE A  20
 None
 0.99A 2bdmA-3wbnA:
undetectable		 2bdmA-3wbnA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dni FUSION PROTEIN OF
RNA-EDITING COMPLEX
PROTEINS MP42 AND
MP18

(Trypanosoma
brucei) 		PF00436
(SSB) 		4 SER A 144
LEU A 112
GLY A  51
THR A  73
 None
 0.90A 2bdmA-4dniA:
undetectable		 2bdmA-4dniA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei8 PLASMID REPLICATION
PROTEIN REPX

(Bacillus cereus) 		PF00091
(Tubulin) 		4 LEU A  23
GLY A 120
THR A 149
ILE A 212
 None
 0.85A 2bdmA-4ei8A:
undetectable		 2bdmA-4ei8A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fix UDP-GALACTOFURANOSYL
TRANSFERASE GLFT2

(Mycobacterium
tuberculosis) 		PF13641
(Glyco_tranf_2_3) 		4 SER A  10
GLY A 284
THR A 349
ILE A 259
 None
 1.11A 2bdmA-4fixA:
undetectable		 2bdmA-4fixA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3m RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Bacillus
subtilis) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		4 SER A 188
LEU A 190
GLY A 291
ILE A 326
 None
None
AI9  A 402 ( 4.0A)
None
 1.10A 2bdmA-4g3mA:
undetectable		 2bdmA-4g3mA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iu9 NITRITE EXTRUSION
PROTEIN 2

(Escherichia
coli) 		no annotation 4 LEU B 278
PHE B 275
GLY B 274
THR B  76
 None
 0.94A 2bdmA-4iu9B:
undetectable		 2bdmA-4iu9B:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdy PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS

(Mycobacterium
tuberculosis) 		PF01680
(SOR_SNZ) 		4 LEU A  22
GLY A  25
THR A 260
ILE A 220
 None
 0.90A 2bdmA-4jdyA:
undetectable		 2bdmA-4jdyA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx8 PERIPLASMIC BINDING
PROTEIN

(Xylanimonas
cellulosilytica) 		PF01497
(Peripla_BP_2) 		4 LEU A 131
GLY A 295
THR A 300
ILE A 167
 None
 0.73A 2bdmA-4mx8A:
undetectable		 2bdmA-4mx8A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pve POLLEN ALLERGEN PHL
P 4.0202

(Phleum pratense) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 MET A 196
LEU A 190
GLY A 188
ILE A  79
 None
 0.99A 2bdmA-4pveA:
undetectable		 2bdmA-4pveA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxg TYPE-2 RESTRICTION
ENZYME SAU3AI

(Staphylococcus
aureus) 		PF02976
(MutH) 		4 LEU A 349
GLY A 169
THR A 171
ILE A 154
 None
 1.11A 2bdmA-4pxgA:
undetectable		 2bdmA-4pxgA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC

(Bordetella
pertussis) 		PF03865
(ShlB)
PF08479
(POTRA_2)
PF17287
(POTRA_3) 		4 LEU A 105
GLY A 109
THR A 169
ILE A 190
 None
PEG  A 602 ( 4.6A)
None
None
 0.75A 2bdmA-4ql0A:
undetectable		 2bdmA-4ql0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qpm MITOTIC CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1

(Homo sapiens) 		PF00069
(Pkinase) 		4 SER A 862
LEU A 864
GLY A 866
ILE A 924
 None
None
None
ADP  A1501 ( 4.5A)
 1.05A 2bdmA-4qpmA:
undetectable		 2bdmA-4qpmA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uhi STEROL 14-ALPHA
DEMETHYLASE

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 308
GLY A 312
THR A 315
ILE A 377
 HEM  A 540 (-4.9A)
HEM  A 540 ( 3.8A)
HEM  A 540 (-3.6A)
HEM  A 540 ( 3.9A)
 0.98A 2bdmA-4uhiA:
26.9		 2bdmA-4uhiA:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5k ASPARTATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Trypanosoma
brucei) 		PF00155
(Aminotran_1_2) 		4 LEU A 362
GLY A 364
THR A 342
ILE A 383
 None
 0.99A 2bdmA-4w5kA:
undetectable		 2bdmA-4w5kA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzh DIHYDROOROTATE
DEHYDROGENASE

(Leishmania
braziliensis) 		PF01180
(DHO_dh) 		4 SER A  45
LEU A  72
GLY A  53
ILE A 212
 FMN  A 401 (-2.6A)
None
None
None
 1.03A 2bdmA-4wzhA:
undetectable		 2bdmA-4wzhA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xjx HSDR

(Escherichia
coli) 		PF04313
(HSDR_N)
PF04851
(ResIII)
PF12008
(EcoR124_C) 		4 LEU A 781
PHE A 778
GLY A 783
ILE A 791
 None
 1.09A 2bdmA-4xjxA:
undetectable		 2bdmA-4xjxA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y67 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE,
APICOPLAST

(Plasmodium
falciparum) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 PHE A 184
GLY A 186
THR A 190
ILE A 227
 None
 1.11A 2bdmA-4y67A:
undetectable		 2bdmA-4y67A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z5q CYTOCHROME P450
HYDROXYLASE

(Streptomyces
atroolivaceus) 		PF00067
(p450) 		4 LEU A 238
PHE A 242
GLY A 241
ILE A 113
 None
None
HEM  A 401 (-3.2A)
None
 1.07A 2bdmA-4z5qA:
23.9		 2bdmA-4z5qA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ab4 SCP2-THIOLASE LIKE
PROTEIN

(Trypanosoma
brucei) 		no annotation 4 MET A  40
LEU A  31
GLY A  12
ILE A 365
 None
 1.00A 2bdmA-5ab4A:
undetectable		 2bdmA-5ab4A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bqn BOTULINUM NEUROTOXIN
TYPE D,BOTULINUM
NEUROTOXIN TYPE D

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		4 SER A 478
PHE A 482
GLY A 678
ILE A 487
 None
 1.05A 2bdmA-5bqnA:
undetectable		 2bdmA-5bqnA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cer BD0816

(Bdellovibrio
bacteriovorus) 		PF02113
(Peptidase_S13) 		4 SER A 239
MET A 235
THR A 301
ILE A 272
 None
 0.81A 2bdmA-5cerA:
undetectable		 2bdmA-5cerA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewq AMIDASE

(Bacillus
anthracis) 		PF01425
(Amidase) 		4 LEU A 517
PHE A 518
GLY A 521
ILE A 358
 None
 0.81A 2bdmA-5ewqA:
undetectable		 2bdmA-5ewqA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exr DNA PRIMASE LARGE
SUBUNIT

(Homo sapiens) 		PF04104
(DNA_primase_lrg) 		4 SER B 352
LEU B 311
GLY B 315
ILE B 276
 None
 1.12A 2bdmA-5exrB:
undetectable		 2bdmA-5exrB:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxf ACRYLYL-COA
REDUCTASE ACUI

(Ruegeria
pomeroyi) 		PF00107
(ADH_zinc_N) 		4 PHE A 132
GLY A 128
THR A  41
ILE A 315
 None
 1.02A 2bdmA-5gxfA:
undetectable		 2bdmA-5gxfA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdi CYTOCHROME P450 144

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 LEU A 272
PHE A 273
GLY A 277
THR A 280
 None
None
None
HEM  A 501 (-4.3A)
 0.87A 2bdmA-5hdiA:
13.9		 2bdmA-5hdiA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijb TOLL-LIKE RECEPTOR
4, VARIABLE
LYMPHOCYTE RECEPTOR
B CHIMERA

(Eptatretus
burgeri;
Mus musculus) 		PF00560
(LRR_1)
PF11921
(DUF3439)
PF13855
(LRR_8) 		4 LEU A 232
GLY A 260
THR A 292
ILE A 299
 None
 1.04A 2bdmA-5ijbA:
undetectable		 2bdmA-5ijbA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jx3 URACIL-DNA
GLYCOSYLASE

(Vaccinia virus) 		no annotation 4 SER A  88
PHE A 189
GLY A 179
ILE A 166
 GOL  A 402 (-3.5A)
None
None
None
 1.00A 2bdmA-5jx3A:
undetectable		 2bdmA-5jx3A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jyd SHORT CHAIN
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF13561
(adh_short_C2) 		4 SER A 259
LEU A 256
GLY A  80
ILE A  98
 None
NAD  A 901 (-3.6A)
NAD  A 901 (-3.0A)
None
 0.92A 2bdmA-5jydA:
undetectable		 2bdmA-5jydA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kia L-THREONINE
3-DEHYDROGENASE

(Burkholderia
thailandensis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 SER A 248
LEU A 168
THR A 156
ILE A 175
 None
 0.97A 2bdmA-5kiaA:
undetectable		 2bdmA-5kiaA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kj8 SYNAPTOTAGMIN-1

(Rattus
norvegicus) 		PF00168
(C2) 		4 SER E 308
LEU E 299
GLY E 374
ILE E 314
 None
 0.93A 2bdmA-5kj8E:
undetectable		 2bdmA-5kj8E:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsu HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2

(Homo sapiens) 		PF00856
(SET) 		4 LEU A1163
PHE A1088
THR A1065
ILE A1067
 None
 0.86A 2bdmA-5lsuA:
undetectable		 2bdmA-5lsuA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m95 DIVALENT METAL
CATION TRANSPORTER
MNTH

(Staphylococcus
capitis) 		PF01566
(Nramp) 		4 SER A 434
GLY A 222
THR A 224
ILE A  71
 None
 1.02A 2bdmA-5m95A:
undetectable		 2bdmA-5m95A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n1t FLAVIN-BINDING
SUBUNIT OF SULFIDE
DEHYDROGENASE

(Thioalkalivibrio
paradoxus) 		no annotation 4 LEU A 231
PHE A 232
GLY A 235
THR A 238
 None
 0.90A 2bdmA-5n1tA:
undetectable		 2bdmA-5n1tA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n2g DNA POLYMERASE

(Vaccinia virus) 		no annotation 4 SER A 111
LEU A 488
GLY A 482
THR A 659
 None
 1.01A 2bdmA-5n2gA:
undetectable		 2bdmA-5n2gA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t77 PUTATIVE LIPID II
FLIPPASE MURJ

(Thermosipho
africanus) 		PF03023
(MVIN) 		4 SER A 353
GLY A 345
THR A 298
ILE A 420
 None
 0.74A 2bdmA-5t77A:
undetectable		 2bdmA-5t77A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ted LMO0488 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 SER B 208
LEU B 205
GLY B 201
THR B 131
 None
None
SKM  B 401 (-3.3A)
SKM  B 401 (-3.3A)
 0.94A 2bdmA-5tedB:
undetectable		 2bdmA-5tedB:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5usd PEPTIDASE S66

(Bacillus
anthracis) 		PF02016
(Peptidase_S66) 		4 LEU A 227
PHE A 226
GLY A 263
ILE A 273
 None
 1.05A 2bdmA-5usdA:
undetectable		 2bdmA-5usdA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vmk BIFUNCTIONAL PROTEIN
GLMU

(Acinetobacter
baumannii) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3)
PF14602
(Hexapep_2) 		4 SER A  18
MET A  16
GLY A  11
ILE A   7
 None
None
PO4  A 502 (-3.3A)
None
 1.02A 2bdmA-5vmkA:
undetectable		 2bdmA-5vmkA:
23.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wbg CYTOCHROME P450 2B6

(Homo sapiens) 		no annotation 4 LEU A 295
PHE A 296
GLY A 299
THR A 303
 HEM  A 501 ( 4.5A)
None
HEM  A 501 ( 3.9A)
HEM  A 501 ( 4.6A)
 0.65A 2bdmA-5wbgA:
39.9		 2bdmA-5wbgA:
86.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfm ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 LEU A 108
PHE A  69
GLY A  61
THR A 149
 None
 0.94A 2bdmA-5xfmA:
undetectable		 2bdmA-5xfmA:
10.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5xxi CYTOCHROME P450 2C9

(Homo sapiens) 		no annotation 4 LEU A 294
PHE A 295
GLY A 298
THR A 302
 HEM  A 504 ( 4.7A)
None
HEM  A 504 (-3.4A)
HEM  A 504 (-4.3A)
 0.39A 2bdmA-5xxiA:
39.4		 2bdmA-5xxiA:
51.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bwy DU-EDITING ENZYME
APOBEC-3G FUSION
PROTECTION OF
TELOMERES PROTEIN 1,
DNA DC->

(Homo sapiens;
Schizosaccharomyces
pombe) 		no annotation 4 LEU A  65
PHE A  47
GLY A  67
ILE A 118
 None
 1.01A 2bdmA-6bwyA:
undetectable		 2bdmA-6bwyA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MONOVALENT CATION/H+
ANTIPORTER SUBUNIT D

(Pyrococcus
furiosus) 		no annotation 4 LEU H 124
GLY H 128
THR H 132
ILE H  76
 None
 0.81A 2bdmA-6cfwH:
undetectable		 2bdmA-6cfwH:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ewj PUTATIVE CAPSULAR
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN

(Streptococcus
pneumoniae) 		no annotation 4 SER A 230
LEU A  55
GLY A 206
THR A 203
 None
 1.11A 2bdmA-6ewjA:
undetectable		 2bdmA-6ewjA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR

(Salmonella
enterica) 		no annotation 4 LEU F  26
GLY F  85
THR F  87
ILE F 254
 None
 1.04A 2bdmA-6f2dF:
undetectable		 2bdmA-6f2dF:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fay ODZ3 PROTEIN

(Mus musculus) 		no annotation 4 LEU A2358
GLY A2356
THR A2317
ILE A2332
 None
 1.08A 2bdmA-6fayA:
undetectable		 2bdmA-6fayA:
12.39