SIMILAR PATTERNS OF AMINO ACIDS FOR 2AZY_A_CHDA237
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ae7 | PHOSPHOLIPASE A2 (Notechisscutatus) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 106TYR A 111 | None | 0.58A | 2azyA-1ae7A:16.8 | 2azyA-1ae7A:48.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bg5 | FUSION PROTEIN OFALPHA-NA,K-ATPASEWITH GLUTATHIONES-TRANSFERASE (Rattusnorvegicus) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | ARG A 73ILE A 72HIS A 79MET A 81TYR A 23 | None | 1.19A | 2azyA-1bg5A:undetectable | 2azyA-1bg5A:17.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bpq | PHOSPHOLIPASE A2 (Bos taurus) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41PHE A 106 | NoneNoneNone CA A 124 (-4.2A)NoneNone | 0.41A | 2azyA-1bpqA:19.9 | 2azyA-1bpqA:83.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bpq | PHOSPHOLIPASE A2 (Bos taurus) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41TYR A 111 | NoneNoneNone CA A 124 (-4.2A)NoneNone | 0.63A | 2azyA-1bpqA:19.9 | 2azyA-1bpqA:83.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bun | BETA2-BUNGAROTOXIN (Bungarusmulticinctus) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 101 | NoneNone NA A 121 (-4.4A) NA A 122 (-4.5A)None | 0.55A | 2azyA-1bunA:17.4 | 2azyA-1bunA:45.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bun | BETA2-BUNGAROTOXIN (Bungarusmulticinctus) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41TYR A 106 | NoneNone NA A 121 (-4.4A) NA A 122 (-4.5A)None | 0.58A | 2azyA-1bunA:17.4 | 2azyA-1bunA:45.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dpy | PHOSPHOLIPASE A2 (Bungaruscaeruleus) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 101TYR A 106 | NoneNone NA A 150 (-4.5A)NoneNoneNone | 0.58A | 2azyA-1dpyA:17.4 | 2azyA-1dpyA:48.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1g0z | PHOSPHOLIPASE A2 (Bungaruscaeruleus) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 101TYR A 106 | None | 0.59A | 2azyA-1g0zA:16.9 | 2azyA-1g0zA:50.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g6g | PROTEIN KINASE RAD53 (Saccharomycescerevisiae) |
PF00498(FHA) | 5 | ILE A 147ASP A 47GLY A 29LEU A 93PHE A 151 | None | 1.18A | 2azyA-1g6gA:undetectable | 2azyA-1g6gA:15.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gp7 | PHOSPHOLIPASE A2 (Ophiophagushannah) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 106 | NoneNone CA A1125 (-4.5A)NoneNone | 0.47A | 2azyA-1gp7A:20.3 | 2azyA-1gp7A:45.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gp7 | PHOSPHOLIPASE A2 (Ophiophagushannah) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41TYR A 111 | NoneNone CA A1125 (-4.5A)NoneNone | 0.73A | 2azyA-1gp7A:20.3 | 2azyA-1gp7A:45.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkx | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE II ALPHACHAIN (Mus musculus) |
PF08332(CaMKII_AD) | 5 | ARG A 346ILE A 350ILE A 429HIS A 420MET A 422 | DTT A1475 ( 3.7A)NoneNoneNoneNone | 1.20A | 2azyA-1hkxA:undetectable | 2azyA-1hkxA:17.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m8t | PHOSPHOLIPASE A2 (Ophiophagushannah) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41PHE A 106 | NoneNoneNone CA A1001 (-4.3A)NoneNone | 0.41A | 2azyA-1m8tA:19.6 | 2azyA-1m8tA:58.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m8t | PHOSPHOLIPASE A2 (Ophiophagushannah) |
PF00068(Phospholip_A2_1) | 5 | ILE A 13TYR A 25GLY A 30LEU A 41TYR A 111 | NoneNone CA A1001 (-4.3A)NoneNone | 0.74A | 2azyA-1m8tA:19.6 | 2azyA-1m8tA:58.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mh2 | PHOSPHOLIPASE A2 (Najasagittifera) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 101 | None | 0.42A | 2azyA-1mh2A:19.5 | 2azyA-1mh2A:46.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mh2 | PHOSPHOLIPASE A2 (Najasagittifera) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41TYR A 106 | None | 0.68A | 2azyA-1mh2A:19.5 | 2azyA-1mh2A:46.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mh8 | PHOSPHOLIPASE A2 (Najasagittifera) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 101 | None | 0.28A | 2azyA-1mh8A:19.2 | 2azyA-1mh8A:49.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mh8 | PHOSPHOLIPASE A2 (Najasagittifera) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41TYR A 106 | None | 0.59A | 2azyA-1mh8A:19.2 | 2azyA-1mh8A:49.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ozy | PHOSPHOLIPASE A2 (Micropechisikaheca) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41PHE A 106 | None | 0.78A | 2azyA-1ozyA:16.5 | 2azyA-1ozyA:56.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ozy | PHOSPHOLIPASE A2 (Micropechisikaheca) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41TYR A 111 | None | 0.94A | 2azyA-1ozyA:16.5 | 2azyA-1ozyA:56.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p7o | PHOSPHOLIPASE A2 (Micropechisikaheca) |
PF00068(Phospholip_A2_1) | 5 | ARG A 6ILE A 9TYR A 25LEU A 41PHE A 106 | None | 1.21A | 2azyA-1p7oA:18.9 | 2azyA-1p7oA:60.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p7o | PHOSPHOLIPASE A2 (Micropechisikaheca) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41PHE A 106 | None | 0.49A | 2azyA-1p7oA:18.9 | 2azyA-1p7oA:60.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p7o | PHOSPHOLIPASE A2 (Micropechisikaheca) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41TYR A 111 | None | 0.70A | 2azyA-1p7oA:18.9 | 2azyA-1p7oA:60.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1po8 | PHOSPHOLIPASE A2 (Bungaruscaeruleus) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 101 | NoneNoneSHV A 122 ( 3.7A)NoneNone | 0.32A | 2azyA-1po8A:17.7 | 2azyA-1po8A:53.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1po8 | PHOSPHOLIPASE A2 (Bungaruscaeruleus) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41TYR A 106 | NoneNoneSHV A 122 ( 3.7A)NoneNone | 0.58A | 2azyA-1po8A:17.7 | 2azyA-1po8A:53.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ppy | ASPARTATE1-DECARBOXYLASEPRECURSOR (Escherichiacoli) |
PF02261(Asp_decarbox) | 5 | ILE A 69ILE A 87MET A 114GLY A 65LEU A 33 | None | 1.13A | 2azyA-1ppyA:undetectable | 2azyA-1ppyA:23.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1psh | PHOSPHOLIPASE A2 (Naja naja) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9TYR A 24GLY A 29LEU A 40PHE A 100TYR A 105 | NoneNone CA A 120 (-4.4A)NoneNoneNone | 0.65A | 2azyA-1pshA:19.3 | 2azyA-1pshA:54.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pwo | PHOSPHOLIPASE A2 (Micropechisikaheca) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41PHE A 106 | None | 0.38A | 2azyA-1pwoA:18.5 | 2azyA-1pwoA:56.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pwo | PHOSPHOLIPASE A2 (Micropechisikaheca) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41TYR A 111 | None | 0.72A | 2azyA-1pwoA:18.5 | 2azyA-1pwoA:56.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rp1 | PANCREATIC LIPASERELATED PROTEIN 1 (Canis lupus) |
PF00151(Lipase)PF01477(PLAT) | 5 | ILE A 344ILE A 420GLY A 348LEU A 444PHE A 400 | None | 1.22A | 2azyA-1rp1A:undetectable | 2azyA-1rp1A:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmk | PURINE NUCLEOSIDEPHOSPHORYLASE (Thermotogamaritima) |
PF01048(PNP_UDP_1) | 5 | ILE A 191ILE A 115GLY A 182PHE A 194TYR A 177 | None | 1.15A | 2azyA-1vmkA:undetectable | 2azyA-1vmkA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xvs | PROTEIN APAG (Vibrio cholerae) |
PF04379(DUF525) | 5 | ILE A 114ILE A 10GLY A 65LEU A 46TYR A 81 | None | 1.19A | 2azyA-1xvsA:undetectable | 2azyA-1xvsA:17.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1y75 | PHOSPHOLIPASE A2ISOFORM 5 (Najasagittifera) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 101 | NoneNoneNAG A 301 (-4.0A)NoneNone | 0.41A | 2azyA-1y75A:18.6 | 2azyA-1y75A:51.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1y75 | PHOSPHOLIPASE A2ISOFORM 6 (Najasagittifera) |
PF00068(Phospholip_A2_1) | 6 | ILE B 9TYR B 25GLY B 30LEU B 41PHE B 101TYR B 106 | None | 0.60A | 2azyA-1y75B:18.7 | 2azyA-1y75B:47.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bud | MALES-ABSENT ON THEFIRST PROTEIN (Drosophilamelanogaster) |
PF11717(Tudor-knot) | 5 | ARG A 387ILE A 385ILE A 432GLY A 418TYR A 413 | None | 1.23A | 2azyA-2budA:undetectable | 2azyA-2budA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cs7 | PNEUMOCOCCALHISTIDINE TRIAD APROTEIN (Streptococcuspneumoniae) |
PF04270(Strep_his_triad) | 5 | ILE A 16HIS A 33GLY A 21LEU A 40TYR A 3 | None ZN A 201 (-3.2A)NoneNoneNone | 1.23A | 2azyA-2cs7A:undetectable | 2azyA-2cs7A:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gvi | CONSERVEDHYPOTHETICAL PROTEIN (Thermoplasmaacidophilum) |
PF02663(FmdE) | 5 | ARG A 104ILE A 151ILE A 143MET A 108TYR A 22 | ACY A 407 ( 4.3A)NoneNoneNoneUNL A 400 (-4.8A) | 0.96A | 2azyA-2gviA:undetectable | 2azyA-2gviA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gzq | PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN (Plasmodiumvivax) |
PF01161(PBP) | 5 | ILE A 135ILE A 181ASP A 90LEU A 10PHE A 184 | None | 1.20A | 2azyA-2gzqA:undetectable | 2azyA-2gzqA:21.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2h4c | PHOSPHOLIPASE A2-II (Daboiasiamensis) |
PF00068(Phospholip_A2_1) | 5 | ILE B 9TYR B 25GLY B 30PHE B 106TYR B 113 | None | 0.60A | 2azyA-2h4cB:14.9 | 2azyA-2h4cB:36.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2isq | CYSTEINE SYNTHASE (Arabidopsisthaliana) |
PF00291(PALP) | 5 | ILE A 165ILE A 173GLY A 184LEU A 202PHE A 176 | NoneNonePLP A 400 ( 4.1A)NoneNone | 1.16A | 2azyA-2isqA:undetectable | 2azyA-2isqA:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k7p | FILAMIN-A (Homo sapiens) |
PF00630(Filamin) | 5 | ARG A1845ILE A1851ILE A1795GLY A1802PHE A1797 | None | 1.23A | 2azyA-2k7pA:undetectable | 2azyA-2k7pA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nw0 | PLYB (unidentifiedphage) |
PF01183(Glyco_hydro_25) | 5 | ARG A 174ILE A 4ILE A 27GLY A 177PHE A 184 | None | 1.21A | 2azyA-2nw0A:undetectable | 2azyA-2nw0A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oca | ATP-DEPENDENT DNAHELICASE UVSW (Escherichiavirus T4) |
PF00271(Helicase_C)PF04851(ResIII) | 5 | ILE A 68ILE A 3HIS A 6GLY A 63LEU A 54 | None | 1.20A | 2azyA-2ocaA:undetectable | 2azyA-2ocaA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oca | ATP-DEPENDENT DNAHELICASE UVSW (Escherichiavirus T4) |
PF00271(Helicase_C)PF04851(ResIII) | 5 | ILE A 68ILE A 3HIS A 6GLY A 274LEU A 54 | None | 0.99A | 2azyA-2ocaA:undetectable | 2azyA-2ocaA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2omv | INTERNALIN-A (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 5 | ILE A 103ILE A 125GLY A 93LEU A 110PHE A 105 | None | 1.21A | 2azyA-2omvA:undetectable | 2azyA-2omvA:12.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2osn | PHOSPHOLIPASE A2ISOFORM 3 (Bungaruscaeruleus) |
PF00068(Phospholip_A2_1) | 6 | ILE A 11TYR A 25GLY A 30LEU A 41PHE A 101TYR A 106 | None | 0.56A | 2azyA-2osnA:16.8 | 2azyA-2osnA:50.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3r | 12-OXOPHYTODIENOATEREDUCTASE 1 (Arabidopsisthaliana) |
PF00724(Oxidored_FMN) | 5 | ILE A 102GLY A 233LEU A 322PHE A 59TYR A 16 | None | 1.04A | 2azyA-2q3rA:undetectable | 2azyA-2q3rA:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yd0 | ENDOPLASMICRETICULUMAMINOPEPTIDASE 1 (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | ILE A 429MET A 366ASP A 371GLY A 377TYR A 245 | None | 1.20A | 2azyA-2yd0A:undetectable | 2azyA-2yd0A:9.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxx | DIAMINOPIMELATEDECARBOXYLASE (Thermotogamaritima) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 5 | ARG A 174ILE A 173HIS A 177GLY A 205LEU A 161 | NoneNonePLP A 401 ( 4.8A)NoneNone | 1.14A | 2azyA-2yxxA:undetectable | 2azyA-2yxxA:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zpk | IGG1-LAMBDA P20.1FAB (HEAVY CHAIN) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | ASP H 62GLY H 65LEU H 80PHE H 69TYR H 90 | NoneGOL H 214 ( 3.7A)NoneNoneNone | 1.14A | 2azyA-2zpkH:undetectable | 2azyA-2zpkH:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a31 | PROBABLETHREONYL-TRNASYNTHETASE 1 (Aeropyrumpernix) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 5 | ARG A 311ILE A 309ILE A 308PHE A 283TYR A 257 | None | 1.19A | 2azyA-3a31A:undetectable | 2azyA-3a31A:11.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3elo | PHOSPHOLIPASE A2 (Homo sapiens) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9ILE A 13TYR A 25LEU A 41PHE A 106 | None | 0.72A | 2azyA-3eloA:16.1 | 2azyA-3eloA:81.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3elo | PHOSPHOLIPASE A2 (Homo sapiens) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9TYR A 25GLY A 30LEU A 41TYR A 111 | None | 1.14A | 2azyA-3eloA:16.1 | 2azyA-3eloA:81.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3elo | PHOSPHOLIPASE A2 (Homo sapiens) |
PF00068(Phospholip_A2_1) | 5 | ILE A 13TYR A 25GLY A 30LEU A 41PHE A 106 | None | 0.64A | 2azyA-3eloA:16.1 | 2azyA-3eloA:81.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hgo | 12-OXOPHYTODIENOATEREDUCTASE 3 (Solanumlycopersicum) |
PF00724(Oxidored_FMN) | 5 | ARG A 233ASP A 232GLY A 235PHE A 59TYR A 16 | None | 1.14A | 2azyA-3hgoA:undetectable | 2azyA-3hgoA:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hgo | 12-OXOPHYTODIENOATEREDUCTASE 3 (Solanumlycopersicum) |
PF00724(Oxidored_FMN) | 5 | ARG A 233GLY A 235LEU A 338PHE A 59TYR A 16 | None | 0.94A | 2azyA-3hgoA:undetectable | 2azyA-3hgoA:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jrv | PROTEIN K7 (Vaccinia virus) |
PF06227(Poxvirus) | 5 | ILE A 26ILE A 20TYR A 33LEU A 57TYR A 54 | None | 1.05A | 2azyA-3jrvA:undetectable | 2azyA-3jrvA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kjr | DIHYDROFOLATEREDUCTASE/THYMIDYLATE SYNTHASE (Babesia bovis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | ILE A 120ASP A 10TYR A 5GLY A 7LEU A 104 | NoneNoneNoneNoneNAP A 512 (-4.8A) | 1.20A | 2azyA-3kjrA:undetectable | 2azyA-3kjrA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mmp | RNA-DIRECTED RNAPOLYMERASE BETACHAIN (Escherichiavirus Qbeta) |
no annotation | 5 | ILE G 139ILE G 135TYR G 327GLY G 235LEU G 299 | None | 1.04A | 2azyA-3mmpG:undetectable | 2azyA-3mmpG:12.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p2p | PHOSPHOLIPASE A2 (Sus scrofa) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9ILE A 13HIS A 17GLY A 30LEU A 41PHE A 106 | NoneNoneNone CA A 125 (-4.3A)NoneNone | 0.83A | 2azyA-3p2pA:19.9 | 2azyA-3p2pA:93.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p2p | PHOSPHOLIPASE A2 (Sus scrofa) |
PF00068(Phospholip_A2_1) | 7 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41PHE A 106TYR A 111 | NoneNoneNone CA A 125 (-4.3A)NoneNoneNone | 0.38A | 2azyA-3p2pA:19.9 | 2azyA-3p2pA:93.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpf | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcuspneumoniae) |
PF06824(Glyco_hydro_125) | 5 | ARG A 82ILE A 85HIS A 73LEU A 37TYR A 33 | NoneNoneEDO A 435 (-4.5A)NoneNone | 1.18A | 2azyA-3qpfA:undetectable | 2azyA-3qpfA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qvq | PHOSPHODIESTERASEOLEI02445 (Oleispiraantarctica) |
PF03009(GDPD) | 5 | ILE A 96ILE A 54TYR A 71GLY A 68PHE A 55 | NoneNoneNone CL A 257 (-3.9A)None | 1.23A | 2azyA-3qvqA:undetectable | 2azyA-3qvqA:18.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3v9m | PHOSPHOLIPASE A2ISOZYME PA-11 (Pseudechisaustralis) |
PF00068(Phospholip_A2_1) | 6 | ILE A 9TYR A 25GLY A 30LEU A 41PHE A 99TYR A 104 | NoneNoneEDO A 201 (-3.5A)NoneNoneNone | 0.60A | 2azyA-3v9mA:17.9 | 2azyA-3v9mA:55.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vbz | PHOSPHOLIPASE A2HOMOLOG, TAIPOXINBETA CHAIN (Oxyuranusscutellatus) |
PF00068(Phospholip_A2_1) | 5 | ILE A 9ILE A 13TYR A 25GLY A 30LEU A 41 | None | 0.57A | 2azyA-3vbzA:17.7 | 2azyA-3vbzA:45.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vbz | PHOSPHOLIPASE A2HOMOLOG, TAIPOXINBETA CHAIN (Oxyuranusscutellatus) |
PF00068(Phospholip_A2_1) | 5 | ILE A 13TYR A 25GLY A 30LEU A 41TYR A 104 | None | 0.93A | 2azyA-3vbzA:17.7 | 2azyA-3vbzA:45.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9u | PUTATIVE LIPASE (Proteusmirabilis) |
PF00561(Abhydrolase_1) | 5 | ARG A 86ILE A 76HIS A 78GLY A 54PHE A 75 | None | 1.23A | 2azyA-3w9uA:undetectable | 2azyA-3w9uA:14.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zcb | ADENOSINEMONOPHOSPHATE-PROTEIN TRANSFERASE VBHT (Bartonellaschoenbuchensis) |
PF02661(Fic) | 5 | ARG A 191ILE A 190ILE A 150TYR A 127TYR A 128 | None | 1.15A | 2azyA-3zcbA:undetectable | 2azyA-3zcbA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4azd | ASPARTATE1-DECARBOXYLASE (Escherichiacoli) |
PF02261(Asp_decarbox) | 5 | ILE A 69ILE A 87MET A 114GLY A 65LEU A 33 | None | 1.14A | 2azyA-4azdA:undetectable | 2azyA-4azdA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0e | NOT1 (Chaetomiumthermophilum) |
PF04054(Not1) | 5 | ILE A1838MET A1784ASP A1785GLY A1791LEU A1819 | None | 1.22A | 2azyA-4c0eA:undetectable | 2azyA-4c0eA:12.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c76 | FMN REDUCTASE(NADPH) (Pseudomonasputida) |
PF03358(FMN_red) | 5 | ILE A 73HIS A 96TYR A 90GLY A 82LEU A 133 | None | 1.02A | 2azyA-4c76A:undetectable | 2azyA-4c76A:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dnh | UNCHARACTERIZEDPROTEIN (Sinorhizobiummeliloti) |
PF06187(DUF993) | 5 | ILE A 154ILE A 144GLY A 229LEU A 180TYR A 176 | None | 1.10A | 2azyA-4dnhA:undetectable | 2azyA-4dnhA:12.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4efh | ACTIN-1 (Acanthamoebacastellanii) |
PF00022(Actin) | 5 | ILE A 309HIS A 275GLY A 156LEU A 185PHE A 306 | NoneNoneADP A 403 (-3.3A)NoneADP A 403 (-3.7A) | 1.20A | 2azyA-4efhA:undetectable | 2azyA-4efhA:15.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4h0s | BASIC PHOSPHOLIPASEA2 HOMOLOG CTS-R6 (Trimeresurusstejnegeri) |
PF00068(Phospholip_A2_1) | 5 | ARG A 6ILE A 9TYR A 25GLY A 30PHE A 106 | None | 0.88A | 2azyA-4h0sA:14.6 | 2azyA-4h0sA:34.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hnn | DIHYDRODIPICOLINATESYNTHASE (Vitis vinifera) |
PF00701(DHDPS) | 5 | ILE A 166ILE A 171GLY A 103LEU A 148PHE A 144 | None | 1.21A | 2azyA-4hnnA:undetectable | 2azyA-4hnnA:13.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j34 | KYNURENINE3-MONOOXYGENASE (Saccharomycescerevisiae) |
PF01494(FAD_binding_3) | 5 | ILE A 232TYR A 374GLY A 324LEU A 193PHE A 246 | None | 0.99A | 2azyA-4j34A:undetectable | 2azyA-4j34A:15.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kxb | GLUTAMYLAMINOPEPTIDASE (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | ILE A 470MET A 406ASP A 411GLY A 417TYR A 285 | None | 1.20A | 2azyA-4kxbA:undetectable | 2azyA-4kxbA:8.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgc | BILE ACID-COENZYME ALIGASE ([Clostridium]scindens) |
PF00501(AMP-binding) | 5 | ILE A 99ILE A 100GLY A 235LEU A 36PHE A 103 | None | 1.15A | 2azyA-4lgcA:undetectable | 2azyA-4lgcA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ma5 | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXYLASE, ATPASESUBUNIT (Francisellatularensis) |
PF02222(ATP-grasp) | 5 | ILE A 230HIS A 108TYR A 240GLY A 194LEU A 244 | None | 1.20A | 2azyA-4ma5A:undetectable | 2azyA-4ma5A:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nkb | PROBABLESERINE/THREONINE-PROTEIN KINASE ZYG-1 (Caenorhabditiselegans) |
no annotation | 5 | ILE A 506MET A 501ASP A 502GLY A 462TYR A 532 | None | 1.16A | 2azyA-4nkbA:undetectable | 2azyA-4nkbA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4plb | CHIMERA PROTEIN OFDNA GYRASE SUBUNITSB AND A (Staphylococcusaureus) |
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim) | 5 | ARG B 479ILE B 478ILE B 461GLY B 488PHE B 523 | None | 1.18A | 2azyA-4plbB:undetectable | 2azyA-4plbB:10.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv1 | CYTOCHROME B6-FCOMPLEX IRON-SULFURSUBUNIT (Mastigocladuslaminosus) |
PF00355(Rieske)PF08802(CytB6-F_Fe-S) | 5 | ILE D 91ILE D 160GLY D 76LEU D 70PHE D 69 | None | 1.16A | 2azyA-4pv1D:undetectable | 2azyA-4pv1D:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q0m | L-ASPARAGINASE (Pyrococcusfuriosus) |
PF00710(Asparaginase) | 5 | ILE A 227ILE A 205MET A 259GLY A 283LEU A 244 | None | 0.97A | 2azyA-4q0mA:undetectable | 2azyA-4q0mA:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qku | HYDROLASE (Burkholderiacenocepacia) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | ILE A 312HIS A 336MET A 337GLY A 362LEU A 215 | None | 1.06A | 2azyA-4qkuA:undetectable | 2azyA-4qkuA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4woj | ASPARTATESEMIALDEHYDEDEHYDROGENASE (Francisellatularensis) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | ILE A 328ILE A 284GLY A 146LEU A 278PHE A 338 | None | 1.19A | 2azyA-4wojA:undetectable | 2azyA-4wojA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wr4 | GLUTATHIONES-TRANSFERASECLASS-MU 26 KDAISOZYME (Schistosomajaponicum) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | ILE A 71ILE A 74GLY A 11LEU A 4TYR A 27 | NoneBYR A 73 ( 4.3A)NoneBYR A 57 ( 4.4A)None | 1.09A | 2azyA-4wr4A:undetectable | 2azyA-4wr4A:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xr7 | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN2 (Saccharomycescerevisiae) |
no annotation | 5 | ARG G 524ILE G 520ILE G 519MET G 529GLY G 551 | None | 1.21A | 2azyA-4xr7G:undetectable | 2azyA-4xr7G:10.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dxx | ARTEMISINIC ALDEHYDEDELTA(11(13))REDUCTASE (Artemisia annua) |
PF00724(Oxidored_FMN) | 5 | ARG A 228GLY A 230LEU A 335PHE A 54TYR A 11 | None | 1.15A | 2azyA-5dxxA:undetectable | 2azyA-5dxxA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e3x | THERMOSTABLECARBOXYPEPTIDASE 1 (Fervidobacteriumislandicum) |
PF02074(Peptidase_M32) | 5 | ILE A 248ILE A 244TYR A 304GLY A 302LEU A 322 | None | 1.18A | 2azyA-5e3xA:undetectable | 2azyA-5e3xA:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ig3 | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE IISUBUNIT ALPHA (Homo sapiens) |
PF08332(CaMKII_AD) | 5 | ARG A 346ILE A 350ILE A 429HIS A 420MET A 422 | None | 1.20A | 2azyA-5ig3A:undetectable | 2azyA-5ig3A:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j0a | LYMPHOKINE-ACTIVATEDKILLERT-CELL-ORIGINATEDPROTEIN KINASE (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 245ILE A 248GLY A 208LEU A 275TYR A 272 | None | 1.21A | 2azyA-5j0aA:undetectable | 2azyA-5j0aA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j8q | CYSTEINE DESULFURASESUFS (Bacillussubtilis) |
PF00266(Aminotran_5) | 5 | ARG A 75ILE A 86ILE A 87GLY A 69PHE A 88 | None | 1.07A | 2azyA-5j8qA:undetectable | 2azyA-5j8qA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxx | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Moraxellacatarrhalis) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | ILE A 81ILE A 63HIS A 94GLY A 125LEU A 112 | None | 1.15A | 2azyA-5jxxA:undetectable | 2azyA-5jxxA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lv9 | THERMOPHILICTRYPTOPHANHALOGENASE (Streptomycesviolaceusniger) |
PF04820(Trp_halogenase) | 5 | ARG A 53ILE A 52ILE A 363GLY A 60LEU A 183 | None | 1.06A | 2azyA-5lv9A:undetectable | 2azyA-5lv9A:13.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lxe | F420-DEPENDENTGLUCOSE-6-PHOSPHATEDEHYDROGENASE 1 (Rhodococcusjostii) |
PF00296(Bac_luciferase) | 5 | ARG A 297ILE A 296ILE A 284TYR A 202GLY A 303 | None | 1.20A | 2azyA-5lxeA:undetectable | 2azyA-5lxeA:14.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7a | ACYLOXYACYLHYDROLASE LARGESUBUNIT (Oryctolaguscuniculus) |
no annotation | 5 | ILE B 256ILE B 364TYR B 416GLY B 264LEU B 543 | None | 1.17A | 2azyA-5w7aB:undetectable | 2azyA-5w7aB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wl2 | - (-) |
no annotation | 5 | ARG H 98ILE H 34ILE H 51GLY H 112TYR H 80 | None | 1.21A | 2azyA-5wl2H:undetectable | 2azyA-5wl2H:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xhw | PUTATIVE6-DEOXY-D-MANNOHEPTOSE PATHWAY PROTEIN (Yersiniapseudotuberculosis) |
no annotation | 5 | ILE A 177ILE A 90GLY A 197LEU A 192PHE A 191 | None | 1.21A | 2azyA-5xhwA:undetectable | 2azyA-5xhwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S4 (Trichomonasvaginalis) |
PF00900(Ribosomal_S4e)PF01479(S4)PF08071(RS4NT)PF16121(40S_S4_C) | 5 | ARG E 100ILE E 101GLY E 91PHE E 47TYR E 82 | None | 1.19A | 2azyA-5xyiE:undetectable | 2azyA-5xyiE:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ez8 | HUNTINGTIN (Homo sapiens) |
no annotation | 5 | ARG A1000ILE A 909HIS A1007GLY A1040LEU A1025 | None | 1.04A | 2azyA-6ez8A:undetectable | 2azyA-6ez8A:undetectable |