SIMILAR PATTERNS OF AMINO ACIDS FOR 2AOU_B_CQAB401

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cp9 PENICILLIN G AMIDASE

(Providencia
rettgeri) 		PF01804
(Penicil_amidase) 		4 GLY B  66
PHE B  57
ASP B 497
THR B  32
 None
 1.11A 2aouB-1cp9B:
undetectable		 2aouB-1cp9B:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ct9 ASPARAGINE
SYNTHETASE B

(Escherichia
coli) 		PF00733
(Asn_synthase)
PF13537
(GATase_7) 		4 GLY A 349
PHE A 403
PRO A 402
ASP A 405
 IUM  A1102 (-3.8A)
None
None
None
 0.80A 2aouB-1ct9A:
undetectable		 2aouB-1ct9A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dms DMSO REDUCTASE

(Rhodobacter
capsulatus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 GLY A  11
PRO A 199
ASP A  35
THR A  39
 None
 1.09A 2aouB-1dmsA:
undetectable		 2aouB-1dmsA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0i PHOSPHOLIPASE D

(Streptomyces
sp. PMF) 		PF13091
(PLDc_2) 		4 TRP A 470
GLY A 274
PRO A 321
ASP A 317
 None
 1.16A 2aouB-1f0iA:
2.3		 2aouB-1f0iA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fno PEPTIDASE T

(Salmonella
enterica) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 GLY A  87
PRO A  83
ASP A  80
THR A  28
 None
 1.15A 2aouB-1fnoA:
undetectable		 2aouB-1fnoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8x MYOSIN II HEAVY
CHAIN FUSED TO
ALPHA-ACTININ 3

(Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 GLY A 287
PHE A 324
ASP A 322
THR A 327
 None
 1.14A 2aouB-1g8xA:
undetectable		 2aouB-1g8xA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h39 SQUALENE--HOPENE
CYCLASE

(Alicyclobacillus
acidocaldarius) 		PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N) 		4 TRP A 558
GLY A 498
ASP A 447
TYR A 495
 None
 0.91A 2aouB-1h39A:
undetectable		 2aouB-1h39A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmz AMINE DEHYDROGENASE

(Pseudomonas
putida) 		PF09098
(Dehyd-heme_bind)
PF09099
(Qn_am_d_aIII)
PF09100
(Qn_am_d_aIV)
PF14930
(Qn_am_d_aII) 		4 GLY A 410
PRO A 413
ASP A 472
TYR A 362
 None
 0.95A 2aouB-1jmzA:
undetectable		 2aouB-1jmzA:
19.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jqe HISTAMINE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF13489
(Methyltransf_23) 		4 TRP A 183
GLY A 187
PHE A 190
THR A 247
 QUN  A 500 (-4.9A)
None
None
None
 1.04A 2aouB-1jqeA:
42.9		 2aouB-1jqeA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jqe HISTAMINE
N-METHYLTRANSFERASE

(Homo sapiens) 		PF13489
(Methyltransf_23) 		4 TRP A 183
PHE A 190
TYR A 198
THR A 247
 QUN  A 500 (-4.9A)
None
None
None
 1.03A 2aouB-1jqeA:
42.9		 2aouB-1jqeA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kv9 TYPE II
QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Pseudomonas
putida) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		4 TRP A 522
GLY A 602
ASP A 107
THR A  55
 None
 1.06A 2aouB-1kv9A:
undetectable		 2aouB-1kv9A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nc7 HYPOTHETICAL PROTEIN
TM1070

(Thermotoga
maritima) 		PF07100
(ASRT) 		4 PHE A   9
PRO A  10
ASP A  11
THR A 108
 None
 0.99A 2aouB-1nc7A:
undetectable		 2aouB-1nc7A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o0s NAD-DEPENDENT MALIC
ENZYME

(Ascaris suum) 		PF00390
(malic)
PF03949
(Malic_M) 		4 GLY A 475
PRO A 463
TYR A 456
THR A 436
 None
 0.97A 2aouB-1o0sA:
4.2		 2aouB-1o0sA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qnl ALIPHATIC AMIDASE
EXPRESSION-REGULATIN
G PROTEIN

(Pseudomonas
aeruginosa) 		PF13433
(Peripla_BP_5) 		4 GLY A  18
PRO A  56
ASP A  59
THR A  87
 None
 1.04A 2aouB-1qnlA:
undetectable		 2aouB-1qnlA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3q QUINOLINE
2-OXIDOREDUCTASE
LARGE SUBUNIT

(Pseudomonas
putida) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 GLY B 541
PHE B 542
ASP B 631
THR B 481
 None
 1.07A 2aouB-1t3qB:
undetectable		 2aouB-1t3qB:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upx HYDROXYLAMINE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF03063
(Prismane) 		4 GLY A 300
PRO A 233
ASP A 258
TYR A 260
 None
 1.13A 2aouB-1upxA:
3.3		 2aouB-1upxA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve1 O-ACETYLSERINE
SULFHYDRYLASE

(Thermus
thermophilus) 		PF00291
(PALP) 		4 GLY A 265
PHE A 246
PRO A 247
ASP A 244
 None
 1.02A 2aouB-1ve1A:
2.8		 2aouB-1ve1A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6s METHANOL
DEHYDROGENASE
SUBUNIT 1
METHANOL
DEHYDROGENASE
SUBUNIT 2

(Methylobacterium
extorquens;
Methylobacterium
extorquens) 		PF01011
(PQQ)
PF13360
(PQQ_2)
PF02315
(MDH) 		4 GLY B1018
PHE B1019
PRO B1020
THR A 268
 None
 1.05A 2aouB-1w6sB:
undetectable		 2aouB-1w6sB:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x7f OUTER SURFACE
PROTEIN

(Bacillus cereus) 		PF05913
(DUF871) 		4 GLY A 310
PHE A 294
PRO A 295
THR A 257
 None
 1.11A 2aouB-1x7fA:
undetectable		 2aouB-1x7fA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmb IAA-AMINO ACID
HYDROLASE HOMOLOG 2

(Arabidopsis
thaliana) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 GLY A 385
PHE A 204
ASP A 388
TYR A 393
 None
 1.12A 2aouB-1xmbA:
undetectable		 2aouB-1xmbA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xn4 RIBONUCLEASE MAR1

(Leishmania
major) 		PF00857
(Isochorismatase) 		4 GLY A 106
PHE A 105
PRO A 130
ASP A 132
 None
 1.01A 2aouB-1xn4A:
3.8		 2aouB-1xn4A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yve ACETOHYDROXY ACID
ISOMEROREDUCTASE

(Spinacia
oleracea) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 GLY I 231
PHE I 228
ASP I 315
THR I 520
 None
None
MG  I 602 (-2.7A)
None
 0.96A 2aouB-1yveI:
4.2		 2aouB-1yveI:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z3a TRNA-SPECIFIC
ADENOSINE DEAMINASE

(Escherichia
coli) 		PF14437
(MafB19-deam) 		4 GLY A 116
PHE A 115
PRO A  97
ASP A 119
 None
 1.18A 2aouB-1z3aA:
undetectable		 2aouB-1z3aA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayx SENSOR KINASE
PROTEIN RCSC

(Escherichia
coli) 		PF00072
(Response_reg)
PF09456
(RcsC) 		4 GLY A 883
PRO A 879
ASP A 832
THR A 903
 None
 1.13A 2aouB-2ayxA:
2.5		 2aouB-2ayxA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2c SPERMIDINE SYNTHASE

(Caenorhabditis
elegans) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 TRP A  43
GLY A  45
ASP A  16
THR A  10
 None
 1.06A 2aouB-2b2cA:
11.3		 2aouB-2b2cA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3x IRON-RESPONSIVE
ELEMENT BINDING
PROTEIN 1

(Homo sapiens) 		PF00330
(Aconitase)
PF00694
(Aconitase_C) 		4 GLY A 213
PHE A 310
PRO A 311
ASP A 313
 None
 0.85A 2aouB-2b3xA:
undetectable		 2aouB-2b3xA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1

(Saccharomyces
cerevisiae) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 TRP A 389
GLY A 722
PRO A 719
THR A 397
 None
 1.14A 2aouB-2cvtA:
2.4		 2aouB-2cvtA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3z BETA-GLUCOSIDASE

(Phanerochaete
chrysosporium) 		PF00232
(Glyco_hydro_1) 		4 GLY A 367
PHE A 368
ASP A 393
THR A 332
 None
 1.18A 2aouB-2e3zA:
undetectable		 2aouB-2e3zA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8l HYPOTHETICAL PROTEIN
LMO1582

(Listeria
monocytogenes) 		PF02384
(N6_Mtase) 		4 GLY A 181
ASP A 204
TYR A 202
THR A 210
 SAM  A 400 (-3.6A)
None
None
None
 1.13A 2aouB-2f8lA:
13.2		 2aouB-2f8lA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5d GNA33

(Neisseria
gonorrhoeae) 		PF03562
(MltA)
PF06725
(3D) 		4 GLY A 278
PHE A 334
ASP A 281
TYR A 279
 None
 1.12A 2aouB-2g5dA:
undetectable		 2aouB-2g5dA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ifa HYPOTHETICAL PROTEIN
SMU.260

(Streptococcus
mutans) 		PF00881
(Nitroreductase) 		4 PHE A  61
ASP A  57
TYR A 162
THR A  95
 None
 1.13A 2aouB-2ifaA:
undetectable		 2aouB-2ifaA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pc1 ACETYLTRANSFERASE,
GNAT FAMILY

(Streptococcus
agalactiae) 		no annotation 4 TRP A  55
GLY A  52
ASP A  71
THR A  94
 None
 1.16A 2aouB-2pc1A:
2.5		 2aouB-2pc1A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r94 2-KETO-3-DEOXY-(6-PH
OSPHO-)GLUCONATE
ALDOLASE

(Thermoproteus
tenax) 		PF00701
(DHDPS) 		4 GLY A  34
PHE A  31
PRO A 278
THR A  29
 None
 1.15A 2aouB-2r94A:
undetectable		 2aouB-2r94A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2taa TAKA-AMYLASE A

(Aspergillus
oryzae) 		PF00128
(Alpha-amylase)
PF09260
(DUF1966) 		4 GLY A 202
PRO A   3
ASP A   5
TYR A 113
 None
 0.89A 2aouB-2taaA:
undetectable		 2aouB-2taaA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vk4 PYRUVATE
DECARBOXYLASE

(Kluyveromyces
lactis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 GLY A 250
PHE A 400
PRO A 401
ASP A 382
 None
 1.19A 2aouB-2vk4A:
2.5		 2aouB-2vk4A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wda PUTATIVE SECRETED
LYASE

(Streptomyces
violaceoruber) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 GLY A 397
PRO A 412
ASP A 531
TYR A 507
 None
 0.88A 2aouB-2wdaA:
undetectable		 2aouB-2wdaA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww9 SEC SIXTY-ONE
PROTEIN HOMOLOG

(Saccharomyces
cerevisiae) 		PF00344
(SecY)
PF10559
(Plug_translocon) 		4 GLY A 176
PRO A  28
ASP A  31
TYR A  35
 None
 0.98A 2aouB-2ww9A:
undetectable		 2aouB-2ww9A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4l FERRIC-SIDEROPHORE
RECEPTOR PROTEIN

(Streptomyces
coelicolor) 		PF01497
(Peripla_BP_2) 		4 TRP A 122
GLY A  94
PHE A  75
THR A 141
 None
 1.04A 2aouB-2x4lA:
undetectable		 2aouB-2x4lA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE

(Flavobacterium
sp.) 		PF00144
(Beta-lactamase) 		4 TRP A 331
GLY A 342
TYR A 326
THR A 220
 MES  A 501 (-4.0A)
None
None
None
 1.16A 2aouB-2zm2A:
undetectable		 2aouB-2zm2A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3af5 PUTATIVE
UNCHARACTERIZED
PROTEIN PH1404

(Pyrococcus
horikoshii) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		4 GLY A 347
ASP A 286
TYR A 472
THR A 322
 None
None
None
ACY  A 660 (-4.0A)
 1.16A 2aouB-3af5A:
undetectable		 2aouB-3af5A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9e CHITINASE A

(Vibrio harveyi) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 GLY A 321
PHE A 316
PRO A 317
ASP A 373
 None
 1.03A 2aouB-3b9eA:
2.7		 2aouB-3b9eA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejw SMLSRB

(Sinorhizobium
meliloti) 		PF13407
(Peripla_BP_4) 		4 GLY A 311
PHE A 313
PRO A 223
THR A 303
 None
 1.09A 2aouB-3ejwA:
3.0		 2aouB-3ejwA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fr8 PUTATIVE KETOL-ACID
REDUCTOISOMERASE
(OS05G0573700
PROTEIN)

(Oryza sativa) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 GLY A 231
PHE A 228
ASP A 315
THR A 520
 None
None
MG  A   1 ( 3.5A)
None
 1.02A 2aouB-3fr8A:
4.2		 2aouB-3fr8A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g12 PUTATIVE
LACTOYLGLUTATHIONE
LYASE

(Bdellovibrio
bacteriovorus) 		no annotation 4 GLY A  20
ASP A 107
TYR A  22
THR A  12
 None
 1.00A 2aouB-3g12A:
undetectable		 2aouB-3g12A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT

(Eubacterium
barkeri) 		PF02738
(Ald_Xan_dh_C2) 		4 GLY B  73
PRO B  79
ASP B  80
THR B  93
 None
 1.09A 2aouB-3hrdB:
undetectable		 2aouB-3hrdB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 GLY X 742
PHE X 657
PRO X 658
ASP X 653
 None
 1.12A 2aouB-3jb9X:
undetectable		 2aouB-3jb9X:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k77 DNA REPAIR PROTEIN
XRCC1

(Homo sapiens) 		PF01834
(XRCC1_N) 		4 GLY A  64
PHE A 142
PRO A 141
ASP A 139
 None
 1.17A 2aouB-3k77A:
undetectable		 2aouB-3k77A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mam OSMOPROTECTION
PROTEIN (PROX)

(Archaeoglobus
fulgidus) 		PF04069
(OpuAC) 		4 GLY A 106
PHE A 107
ASP A 244
THR A 192
 None
None
None
EPE  A 278 (-4.5A)
 1.12A 2aouB-3mamA:
undetectable		 2aouB-3mamA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgf FLUORESCENT PROTEIN

(Verrillofungia
concinna) 		PF01353
(GFP) 		4 GLY A  37
PHE A  71
PRO A  70
TYR A  35
 None
 1.11A 2aouB-3mgfA:
undetectable		 2aouB-3mgfA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nqp SUSD SUPERFAMILY
PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 GLY A 161
ASP A 246
TYR A 156
THR A 192
 None
 1.15A 2aouB-3nqpA:
undetectable		 2aouB-3nqpA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ocq PUTATIVE
CYTOSINE/ADENOSINE
DEAMINASE

(Salmonella
enterica) 		PF14437
(MafB19-deam) 		4 GLY A 116
PHE A 115
PRO A  97
ASP A 119
 None
 1.17A 2aouB-3ocqA:
undetectable		 2aouB-3ocqA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pc3 CG1753, ISOFORM A

(Drosophila
melanogaster) 		PF00291
(PALP)
PF00571
(CBS) 		4 GLY A 317
PHE A 301
PRO A 302
ASP A 299
 None
 0.81A 2aouB-3pc3A:
2.1		 2aouB-3pc3A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pps LACCASE

(Thielavia
arenaria) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 GLY A 147
ASP A 236
TYR A 177
THR A 188
 None
 1.19A 2aouB-3ppsA:
undetectable		 2aouB-3ppsA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6p CAPSID PROTEIN

(Helicoverpa
armigera stunt
virus) 		PF03566
(Peptidase_A21) 		4 GLY A 548
PRO A 118
ASP A 119
THR A 244
 None
 0.96A 2aouB-3s6pA:
undetectable		 2aouB-3s6pA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgi DNA LIGASE

(Mycobacterium
tuberculosis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB) 		4 GLY A  75
PHE A  80
ASP A 152
THR A 143
 None
 1.08A 2aouB-3sgiA:
undetectable		 2aouB-3sgiA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfj GCVT-LIKE
AMINOMETHYLTRANSFERA
SE PROTEIN

(Candidatus
Pelagibacter
ubique) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 GLY A 261
PHE A 262
PRO A 257
ASP A 255
 None
 1.19A 2aouB-3tfjA:
undetectable		 2aouB-3tfjA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wa5 TSE3-SPECIFIC
IMMUNITY PROTEIN

(Pseudomonas
aeruginosa) 		no annotation 4 GLY B  41
PHE B  42
PRO B  39
ASP B  23
 None
 1.10A 2aouB-3wa5B:
undetectable		 2aouB-3wa5B:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wc3 ENDO-1,
4-BETA-GLUCANASE

(Eisenia fetida) 		PF00759
(Glyco_hydro_9) 		4 GLY A 259
ASP A 289
TYR A 256
THR A 282
 None
None
None
GOL  A 506 (-4.0A)
 1.03A 2aouB-3wc3A:
undetectable		 2aouB-3wc3A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wc3 ENDO-1,
4-BETA-GLUCANASE

(Eisenia fetida) 		PF00759
(Glyco_hydro_9) 		4 GLY A 321
PRO A 414
ASP A 415
THR A 310
 None
None
GOL  A 507 (-4.4A)
None
 1.17A 2aouB-3wc3A:
undetectable		 2aouB-3wc3A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsy SORTILIN-RELATED
RECEPTOR

(Homo sapiens) 		PF15901
(Sortilin_C)
PF15902
(Sortilin-Vps10) 		4 GLY A 331
PHE A 330
ASP A 304
TYR A 258
 None
 1.15A 2aouB-3wsyA:
undetectable		 2aouB-3wsyA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apb FUMARATE HYDRATASE
CLASS II

(Mycobacterium
tuberculosis) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 GLY A 227
PHE A 241
PRO A 238
ASP A 240
 None
 0.88A 2aouB-4apbA:
undetectable		 2aouB-4apbA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g56 HSL7 PROTEIN

(Xenopus laevis) 		PF05185
(PRMT5)
PF17285
(PRMT5_TIM)
PF17286
(PRMT5_C) 		4 GLY A 205
PRO A 155
ASP A 157
THR A 181
 None
 0.93A 2aouB-4g56A:
9.3		 2aouB-4g56A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gf2 ERYTHROCYTE BINDING
ANTIGEN 140

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 GLY A 455
PHE A 454
ASP A 450
THR A 424
 None
GOL  A 807 (-3.4A)
None
GOL  A 807 ( 4.3A)
 1.17A 2aouB-4gf2A:
undetectable		 2aouB-4gf2A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grh AMINODEOXYCHORISMATE
SYNTHASE

(Stenotrophomonas
maltophilia) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		4 GLY A 194
PHE A 191
ASP A 186
THR A 439
 None
 1.13A 2aouB-4grhA:
undetectable		 2aouB-4grhA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gvf BETA-HEXOSAMINIDASE

(Salmonella
enterica) 		PF00933
(Glyco_hydro_3) 		4 TRP A 230
PRO A 180
ASP A 182
TYR A 216
 None
 1.14A 2aouB-4gvfA:
undetectable		 2aouB-4gvfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ig9 NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-1

(Homo sapiens) 		PF02146
(SIR2) 		4 PHE A 287
PRO A 288
ASP A 289
TYR A 301
 None
 1.01A 2aouB-4ig9A:
2.3		 2aouB-4ig9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 GLY A 204
PHE A1146
ASP A1142
TYR A1143
 None
 1.16A 2aouB-4iglA:
undetectable		 2aouB-4iglA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ijr D-ARABINOSE
DEHYDROGENASE
[NAD(P)+] HEAVY
CHAIN

(Saccharomyces
cerevisiae) 		PF00248
(Aldo_ket_red) 		4 PHE A 325
PRO A 324
TYR A 161
THR A 151
 None
 1.19A 2aouB-4ijrA:
undetectable		 2aouB-4ijrA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkl BETA-GLUCURONIDASE

(Streptococcus
agalactiae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 GLY A 166
PHE A  44
ASP A  46
TYR A 164
 None
 1.18A 2aouB-4jklA:
undetectable		 2aouB-4jklA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jre NITRITE EXTRUSION
PROTEIN 1

(Escherichia
coli) 		PF07690
(MFS_1) 		4 TRP A 118
GLY A 120
PHE A 121
ASP A 125
 None
 1.15A 2aouB-4jreA:
undetectable		 2aouB-4jreA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3b OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMA

(Neisseria
gonorrhoeae) 		PF01103
(Bac_surface_Ag)
PF07244
(POTRA) 		4 GLY A  69
PHE A  71
ASP A  73
TYR A  66
 None
 0.95A 2aouB-4k3bA:
undetectable		 2aouB-4k3bA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mzd NISIN LEADER
PEPTIDE-PROCESSING
SERINE PROTEASE NISP

(Lactococcus
lactis) 		PF00082
(Peptidase_S8) 		4 GLY A 510
PHE A 513
ASP A 233
THR A 498
 None
 0.69A 2aouB-4mzdA:
undetectable		 2aouB-4mzdA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4or2 SOLUBLE CYTOCHROME
B562, METABOTROPIC
GLUTAMATE RECEPTOR 1

(Escherichia
coli;
Homo sapiens) 		PF00003
(7tm_3)
PF07361
(Cytochrom_B562) 		4 PRO A1056
ASP A1060
TYR A1105
THR A 653
 None
None
None
CLR  A1905 (-3.4A)
 1.01A 2aouB-4or2A:
undetectable		 2aouB-4or2A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4g SHIKIMATE
5-DEHYDROGENASE AROE
(5-DEHYDROSHIKIMATE
REDUCTASE)

(Mycobacterium
tuberculosis) 		PF08501
(Shikimate_dh_N) 		4 GLY A 135
PRO A 130
ASP A 105
THR A 191
 None
None
SKM  A 301 (-2.8A)
None
 1.19A 2aouB-4p4gA:
4.9		 2aouB-4p4gA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psp ALPHA-FUCOSIDASE
GH29

(Fusarium
graminearum) 		PF01120
(Alpha_L_fucos)
PF16757
(Fucosidase_C) 		4 TRP A 287
GLY A 337
ASP A 303
THR A 270
 None
None
GOL  A 622 (-2.6A)
None
 1.15A 2aouB-4pspA:
undetectable		 2aouB-4pspA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rae HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00155
(Aminotran_1_2) 		4 GLY A 122
PHE A 170
ASP A 201
TYR A 127
 None
 0.86A 2aouB-4raeA:
undetectable		 2aouB-4raeA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rco PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF02876
(Stap_Strp_tox_C)
PF09199
(SSL_OB) 		4 GLY A 139
ASP A 168
TYR A 172
THR A 202
 None
 1.17A 2aouB-4rcoA:
undetectable		 2aouB-4rcoA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rit PYRIDOXAL-DEPENDENT
DECARBOXYLASE

(Sphaerobacter
thermophilus) 		no annotation 4 GLY B 410
PHE B 394
PRO B 393
ASP B 413
 None
 1.18A 2aouB-4ritB:
undetectable		 2aouB-4ritB:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uyp CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B

(Acetivibrio
cellulolyticus) 		no annotation 4 GLY B  37
PHE B  32
PRO B  33
ASP B   8
 EPE  B1076 ( 4.6A)
None
None
CA  B 201 (-2.9A)
 1.08A 2aouB-4uypB:
undetectable		 2aouB-4uypB:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5u CHITINASE

(Streptomyces
thermoviolaceus) 		no annotation 4 TRP B 388
GLY B 303
PHE B 304
ASP B 335
 None
 1.15A 2aouB-4w5uB:
undetectable		 2aouB-4w5uB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wa0 POSSIBLE ADHESIN

(Caldicellulosiruptor
kronotskyensis) 		no annotation 4 GLY A 497
PRO A 471
ASP A 473
THR A 483
 None
None
MG  A 601 (-3.3A)
None
 1.16A 2aouB-4wa0A:
undetectable		 2aouB-4wa0A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4za3 RRNA N-GLYCOSIDASE

(Momordica
charantia) 		PF00652
(Ricin_B_lectin) 		4 GLY B 226
PHE B 122
ASP B 178
THR B  94
 None
 1.01A 2aouB-4za3B:
undetectable		 2aouB-4za3B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzh NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-1

(Homo sapiens) 		PF02146
(SIR2) 		4 PHE A 287
PRO A 288
ASP A 289
TYR A 301
 None
 1.08A 2aouB-4zzhA:
2.5		 2aouB-4zzhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5btr NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-1

(Homo sapiens) 		PF02146
(SIR2) 		4 PHE A 287
PRO A 288
ASP A 289
TYR A 301
 None
 0.88A 2aouB-5btrA:
2.3		 2aouB-5btrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Bacillus
pumilus) 		PF02011
(Glyco_hydro_48) 		4 GLY A 413
PHE A 412
ASP A 530
THR A 528
 None
 1.18A 2aouB-5bv9A:
undetectable		 2aouB-5bv9A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bz0 REPLICASE
POLYPROTEIN 1AB

(Avian
coronavirus) 		PF08715
(Viral_protease) 		4 GLY A 252
ASP A 247
TYR A 294
THR A 202
 None
 0.87A 2aouB-5bz0A:
undetectable		 2aouB-5bz0A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 PHE A 285
PRO A 242
TYR A 339
THR A 140
 None
COI  A 601 ( 4.4A)
None
None
 1.13A 2aouB-5ereA:
5.0		 2aouB-5ereA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7c ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 GLY A 207
PHE A 243
PRO A 242
TYR A 244
 None
 1.18A 2aouB-5f7cA:
undetectable		 2aouB-5f7cA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5n LH3
HEXON-INTERLACING
CAPSID PROTEIN

(Snake
atadenovirus A) 		PF01696
(Adeno_E1B_55K) 		4 GLY A  70
PRO A  51
TYR A  55
THR A  30
 None
 1.18A 2aouB-5g5nA:
undetectable		 2aouB-5g5nA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8w ATP-DEPENDENT DNA
HELICASE TA0057

(Thermoplasma
acidophilum) 		PF06733
(DEAD_2)
PF06777
(HBB)
PF13307
(Helicase_C_2) 		4 GLY A 396
PHE A 397
TYR A 391
THR A 378
 None
 1.16A 2aouB-5h8wA:
5.3		 2aouB-5h8wA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ll1 URICASE

(Danio rerio) 		PF01014
(Uricase) 		4 GLY A  17
PRO A  62
ASP A  64
THR A  69
 None
 1.03A 2aouB-5ll1A:
undetectable		 2aouB-5ll1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncc FATTY ACID
PHOTODECARBOXYLASE

(Chlorella
variabilis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 GLY A 165
PRO A 117
ASP A 118
TYR A 277
 FAD  A 701 (-3.1A)
None
None
None
 1.10A 2aouB-5nccA:
undetectable		 2aouB-5nccA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngw OPGH99A

(Ochrovirga
pacifica) 		no annotation 4 TRP A 264
PRO A 221
TYR A 241
THR A  16
 None
BR  A 402 (-4.8A)
None
None
 1.10A 2aouB-5ngwA:
2.1		 2aouB-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc1 ARYL-ALCOHOL OXIDASE

(Pleurotus
eryngii) 		no annotation 4 TRP A 363
GLY A 193
PRO A 184
THR A 188
 None
 1.15A 2aouB-5oc1A:
2.1		 2aouB-5oc1A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x9y DNA MISMATCH REPAIR
PROTEIN MUTL

(Aquifex
aeolicus) 		no annotation 4 GLY C  55
PHE C 107
PRO C  58
ASP C  60
 None
 0.94A 2aouB-5x9yC:
undetectable		 2aouB-5x9yC:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bac ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Neisseria
gonorrhoeae) 		no annotation 4 GLY A 145
PHE A 148
ASP A 151
THR A 260
 None
 0.97A 2aouB-6bacA:
undetectable		 2aouB-6bacA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8s LOGANIC ACID
O-METHYLTRANSFERASE

(Catharanthus
roseus) 		no annotation 4 GLY A 137
PHE A 112
ASP A 114
THR A  84
 None
None
SAH  A 401 (-2.8A)
None
 1.16A 2aouB-6c8sA:
17.3		 2aouB-6c8sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfs PHOSPHOMANNOMUTASE 1

(Homo sapiens) 		no annotation 4 GLY A  49
PHE A  18
ASP A  19
THR A 246
 None
None
MG  A 301 (-2.4A)
None
 1.17A 2aouB-6cfsA:
undetectable		 2aouB-6cfsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6czm -

(-) 		no annotation 4 TRP A  86
GLY A  43
PRO A  90
ASP A  92
 None
 0.94A 2aouB-6czmA:
undetectable		 2aouB-6czmA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoq DIPEPTIDYL PEPTIDASE
9

(Homo sapiens) 		no annotation 4 GLY A 780
PRO A 774
ASP A 772
THR A 767
 None
 1.04A 2aouB-6eoqA:
2.3		 2aouB-6eoqA:
undetectable