SIMILAR PATTERNS OF AMINO ACIDS FOR 2AOI_C_FRDC305_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eh6 | O6-ALKYLGUANINE-DNAALKYLTRANSFERASE (Homo sapiens) |
PF01035(DNA_binding_1)PF02870(Methyltransf_1N) | 4 | LEU A 142PRO A 138VAL A 139ILE A 143 | None | 0.83A | 2aoiB-1eh6A:undetectable | 2aoiB-1eh6A:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gp1 | GLUTATHIONEPEROXIDASE (Bos taurus) |
PF00255(GSHPx) | 4 | LEU A 36PRO A 171VAL A 165ILE A 38 | None | 0.99A | 2aoiB-1gp1A:undetectable | 2aoiB-1gp1A:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h1y | D-RIBULOSE-5-PHOSPHATE 3-EPIMERASE (Oryza sativa) |
PF00834(Ribul_P_3_epim) | 4 | LEU A 216PRO A 209VAL A 212ILE A 213 | None | 1.00A | 2aoiB-1h1yA:undetectable | 2aoiB-1h1yA:18.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | LEU A 23ASP A 25PRO A 81VAL A 82ILE A 84 | A79 A 800 ( 3.8A)A79 A 800 (-2.7A)A79 A 800 ( 3.9A)A79 A 800 (-4.5A)A79 A 800 (-3.6A) | 0.47A | 2aoiB-1hvcA:14.0 | 2aoiB-1hvcA:46.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | LEU A 23ASP A 25PRO A 81VAL A 82ILE A 84 | A79 A 800 ( 4.0A)A79 A 800 (-2.8A)A79 A 800 ( 3.4A)A79 A 800 (-4.5A)A79 A 800 (-3.8A) | 0.35A | 2aoiB-1hvcA:14.0 | 2aoiB-1hvcA:46.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1is1 | RIBOSOME RECYCLINGFACTOR (Vibrioparahaemolyticus) |
PF01765(RRF) | 4 | LEU A 65PRO A 91VAL A 100ILE A 67 | None | 0.94A | 2aoiB-1is1A:undetectable | 2aoiB-1is1A:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jeq | KU70 (Homo sapiens) |
PF02037(SAP)PF02735(Ku)PF03730(Ku_C)PF03731(Ku_N) | 4 | LEU A 261PRO A 370VAL A 271ILE A 269 | None | 0.98A | 2aoiB-1jeqA:undetectable | 2aoiB-1jeqA:9.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jfi | TRANSCRIPTIONREGULATOR NC2 BETACHAIN (Homo sapiens) |
PF00808(CBFD_NFYB_HMF) | 4 | LEU B 175PRO B 168VAL B 171ILE B 172 | None | 1.01A | 2aoiB-1jfiB:undetectable | 2aoiB-1jfiB:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m2p | CASEIN KINASE II,ALPHA CHAIN (Zea mays) |
PF00069(Pkinase) | 4 | LEU A 171PRO A 159VAL A 162ILE A 164 | None | 0.95A | 2aoiB-1m2pA:undetectable | 2aoiB-1m2pA:13.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozn | RETICULON 4 RECEPTOR (Homo sapiens) |
PF13855(LRR_8) | 4 | LEU A 88PRO A 73VAL A 72ILE A 69 | None | 1.01A | 2aoiB-1oznA:undetectable | 2aoiB-1oznA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qnt | METHYLATED-DNA--PROTEIN-CYSTEINEMETHYLTRANSFERASE (Homo sapiens) |
PF01035(DNA_binding_1)PF02870(Methyltransf_1N) | 4 | LEU A 142PRO A 138VAL A 139ILE A 143 | None | 0.84A | 2aoiB-1qntA:undetectable | 2aoiB-1qntA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qrp | PEPSIN 3A (Homo sapiens) |
PF00026(Asp) | 4 | LEU E 155ASP E 303VAL E 153ILE E 306 | None | 0.98A | 2aoiB-1qrpE:6.9 | 2aoiB-1qrpE:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rf5 | 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATESYNTHASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 4 | LEU A 253PRO A 17VAL A 16ILE A 14 | None | 1.01A | 2aoiB-1rf5A:undetectable | 2aoiB-1rf5A:13.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1shz | GUANINENUCLEOTIDE-BINDINGPROTEINGALPHA(13):GALPHA(I1) CHIMERA (Mus musculus;Rattusnorvegicus) |
PF00503(G-alpha) | 4 | LEU A 152ASP A 155VAL A 100ILE A 158 | None | 0.91A | 2aoiB-1shzA:undetectable | 2aoiB-1shzA:14.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | None | 0.39A | 2aoiB-1sivA:18.6 | 2aoiB-1sivA:51.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tnd | TRANSDUCIN (Bos taurus) |
PF00503(G-alpha) | 4 | LEU A 126ASP A 129VAL A 81ILE A 132 | None | 0.98A | 2aoiB-1tndA:undetectable | 2aoiB-1tndA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6z | HYPOTHETICAL PROTEINTTHA0657 (Thermusthermophilus) |
PF04452(Methyltrans_RNA) | 4 | LEU A 103PRO A 150VAL A 149ILE A 144 | None | 0.86A | 2aoiB-1v6zA:undetectable | 2aoiB-1v6zA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9n | MALATE DEHYDROGENASE (Pyrococcushorikoshii) |
PF02615(Ldh_2) | 4 | LEU A 19ASP A 48VAL A 14ILE A 338 | None | 0.99A | 2aoiB-1v9nA:undetectable | 2aoiB-1v9nA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vp5 | 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE (Thermotogamaritima) |
PF00248(Aldo_ket_red) | 4 | LEU A 43ASP A 45VAL A 229ILE A 231 | NoneNAP A 300 (-3.7A)NoneNAP A 300 (-4.7A) | 0.95A | 2aoiB-1vp5A:undetectable | 2aoiB-1vp5A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wac | P2 PROTEIN (Pseudomonasvirus phi6) |
PF00680(RdRP_1) | 4 | LEU A 252PRO A 261VAL A 260ILE A 258 | None | 0.80A | 2aoiB-1wacA:undetectable | 2aoiB-1wacA:10.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x5r | GLUTAMATE RECEPTORINTERACTING PROTEIN2 (Homo sapiens) |
PF00595(PDZ) | 4 | LEU A 101PRO A 47VAL A 70ILE A 73 | None | 1.02A | 2aoiB-1x5rA:undetectable | 2aoiB-1x5rA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z1n | SIXTEEN HEMECYTOCHROME (Desulfovibriogigas) |
PF02085(Cytochrom_CIII)PF14522(Cytochrome_C7) | 4 | LEU X 460ASP X 458PRO X 408VAL X 407 | NoneNoneNoneHEC X 613 (-4.2A) | 0.99A | 2aoiB-1z1nX:undetectable | 2aoiB-1z1nX:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exh | BETA-D-XYLOSIDASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43) | 4 | LEU A 433PRO A 455VAL A 454ILE A 452 | None | 0.84A | 2aoiB-2exhA:undetectable | 2aoiB-2exhA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f8a | GLUTATHIONEPEROXIDASE 1 (Homo sapiens) |
PF00255(GSHPx) | 4 | LEU A 38PRO A 173VAL A 167ILE A 40 | None | 0.95A | 2aoiB-2f8aA:undetectable | 2aoiB-2f8aA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fcr | FLAVODOXIN (Chondruscrispus) |
PF00258(Flavodoxin_1) | 4 | LEU A 51PRO A 120VAL A 87ILE A 89 | None | 0.97A | 2aoiB-2fcrA:undetectable | 2aoiB-2fcrA:20.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fmb | EQUINE INFECTIOUSANEMIA VIRUSPROTEASE (Equineinfectiousanemia virus) |
PF00077(RVP) | 5 | LEU A 23ASP A 25PRO A 86VAL A 87ILE A 89 | NoneLP1 A 201 (-2.3A)LP1 A 201 (-3.9A)LP1 A 201 ( 4.9A)LP1 A 201 (-4.2A) | 0.57A | 2aoiB-2fmbA:15.0 | 2aoiB-2fmbA:33.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g28 | PYRUVATEDEHYDROGENASE E1COMPONENT (Escherichiacoli) |
PF00456(Transketolase_N) | 4 | LEU A 565PRO A 594VAL A 516ILE A 518 | None | 0.88A | 2aoiB-2g28A:undetectable | 2aoiB-2g28A:8.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lnv | GENERAL SECRETIONPATHWAY PROTEIN C (Dickeyadadantii) |
PF11356(T2SSC) | 4 | LEU A 145PRO A 129VAL A 128ILE A 135 | None | 0.90A | 2aoiB-2lnvA:undetectable | 2aoiB-2lnvA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2onk | MOLYBDATE/TUNGSTATEABC TRANSPORTER,PERMEASE PROTEIN (Archaeoglobusfulgidus) |
PF00528(BPD_transp_1) | 4 | LEU C 216PRO C 231VAL C 232ILE C 217 | None | 1.01A | 2aoiB-2onkC:undetectable | 2aoiB-2onkC:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pgg | RNA-DIRECTED RNAPOLYMERASE (Infectiousbursal diseasevirus) |
PF04197(Birna_RdRp) | 4 | LEU A 581PRO A 586VAL A 585ILE A 583 | None | 1.01A | 2aoiB-2pggA:undetectable | 2aoiB-2pggA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pok | PEPTIDASE,M20/M25/M40 FAMILY (Streptococcuspneumoniae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | LEU A 85PRO A 146VAL A 147ILE A 149 | None | 0.75A | 2aoiB-2pokA:undetectable | 2aoiB-2pokA:13.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjp | CYTOCHROME B (Rhodobactersphaeroides) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 4 | LEU A 377ASP A 373VAL A 380ILE A 376 | None | 0.83A | 2aoiB-2qjpA:undetectable | 2aoiB-2qjpA:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r05 | PROGRAMMED CELLDEATH 6-INTERACTINGPROTEIN (Homo sapiens) |
PF03097(BRO1)PF13949(ALIX_LYPXL_bnd) | 4 | LEU A 530PRO A 414VAL A 413ILE A 534 | None | 0.98A | 2aoiB-2r05A:undetectable | 2aoiB-2r05A:11.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rkf | PROTEASE RETROPEPSIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | NoneAB1 A 501 (-2.4A)AB1 A 501 (-4.2A)AB1 A 501 ( 4.2A) | 0.42A | 2aoiB-2rkfA:20.6 | 2aoiB-2rkfA:82.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x7i | MEVALONATE KINASE (Staphylococcusaureus) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | LEU A 15PRO A 154VAL A 30ILE A 28 | None | 0.89A | 2aoiB-2x7iA:undetectable | 2aoiB-2x7iA:14.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x9p | PIMD PROTEIN (Streptomycesnatalensis) |
PF00067(p450) | 4 | LEU A 57ASP A 60VAL A 307ILE A 63 | None | 0.97A | 2aoiB-2x9pA:undetectable | 2aoiB-2x9pA:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ykq | LINE-1 ORF1P (Homo sapiens) |
PF02994(Transposase_22)PF17489(Tnp_22_trimer)PF17490(Tnp_22_dsRBD) | 4 | LEU A 160PRO A 164VAL A 163ILE A 247 | None | 0.99A | 2aoiB-2ykqA:undetectable | 2aoiB-2ykqA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a79 | TOLL-LIKE RECEPTOR6, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Mus musculus) |
PF11921(DUF3439)PF13855(LRR_8) | 4 | LEU B 67PRO B 47VAL B 46ILE B 64 | None | 0.94A | 2aoiB-3a79B:undetectable | 2aoiB-3a79B:8.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abs | ETHANOLAMINEAMMONIA-LYASE LIGHTCHAIN (Escherichiacoli) |
PF05985(EutC) | 4 | LEU B 225PRO B 199VAL B 163ILE B 165 | None | 1.01A | 2aoiB-3absB:undetectable | 2aoiB-3absB:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3agk | PEPTIDE CHAINRELEASE FACTORSUBUNIT 1 (Aeropyrumpernix) |
PF03464(eRF1_2)PF03465(eRF1_3) | 4 | LEU A 320PRO A 346VAL A 345ILE A 343 | None | 0.78A | 2aoiB-3agkA:undetectable | 2aoiB-3agkA:12.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3any | ETHANOLAMINEAMMONIA-LYASE LIGHTCHAIN (Escherichiacoli) |
PF05985(EutC) | 4 | LEU B 225PRO B 199VAL B 163ILE B 165 | None | 0.96A | 2aoiB-3anyB:undetectable | 2aoiB-3anyB:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqw | PUTATIVE CAPSIDPROTEIN OF PROPHAGE (Escherichiacoli) |
PF03864(Phage_cap_E) | 4 | LEU A 52ASP A 53VAL A 57ILE A 54 | None | 0.98A | 2aoiB-3bqwA:undetectable | 2aoiB-3bqwA:15.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddn | D-3-PHOSPHOGLYCERATEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00389(2-Hacid_dh)PF01842(ACT)PF02826(2-Hacid_dh_C) | 4 | LEU A 502ASP A 503PRO A 507VAL A 506 | None | 0.98A | 2aoiB-3ddnA:undetectable | 2aoiB-3ddnA:11.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dqg | HEAT SHOCK 70 KDAPROTEIN F (Caenorhabditiselegans) |
PF00012(HSP70) | 4 | LEU A 484ASP A 515VAL A 461ILE A 487 | None | 0.98A | 2aoiB-3dqgA:undetectable | 2aoiB-3dqgA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dxn | CALMODULIN-LIKEDOMAIN PROTEINKINASE ISOFORM 3 (Toxoplasmagondii) |
PF00069(Pkinase) | 4 | LEU A 231ASP A 227VAL A 234ILE A 230 | None | 0.87A | 2aoiB-3dxnA:undetectable | 2aoiB-3dxnA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3b | CASEIN KINASE IISUBUNIT ALPHA' (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU X 172PRO X 160VAL X 163ILE X 165 | None | 0.87A | 2aoiB-3e3bX:undetectable | 2aoiB-3e3bX:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gs9 | PROTEIN GP18 (Listeriamonocytogenes) |
PF06605(Prophage_tail) | 5 | LEU A 157ASP A 154PRO A 166VAL A 164ILE A 153 | None | 1.35A | 2aoiB-3gs9A:undetectable | 2aoiB-3gs9A:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzt | CALCIUM-DEPENDENTPROTEIN KINASE 3 (Toxoplasmagondii) |
PF00069(Pkinase)PF13499(EF-hand_7) | 4 | LEU A 284ASP A 280VAL A 287ILE A 283 | None | 0.91A | 2aoiB-3hztA:undetectable | 2aoiB-3hztA:12.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzz | SNAP-TAG (Homo sapiens) |
PF01035(DNA_binding_1)PF02870(Methyltransf_1N) | 4 | LEU A 142PRO A 138VAL A 139ILE A 143 | None | 0.80A | 2aoiB-3kzzA:undetectable | 2aoiB-3kzzA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxu | TRIPEPTIDYL-PEPTIDASE 2 (Drosophilamelanogaster) |
PF00082(Peptidase_S8)PF12580(TPPII)PF12583(TPPII_N) | 4 | LEU X 757PRO X 691VAL X 690ILE X 688 | None | 0.79A | 2aoiB-3lxuX:undetectable | 2aoiB-3lxuX:5.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mws | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | LEU A 23ASP A 25PRO A 81VAL A 82ILE A 84 | None | 0.28A | 2aoiB-3mwsA:19.6 | 2aoiB-3mwsA:79.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o82 | PEPTIDE ARYLATIONENZYME (Acinetobacterbaumannii) |
PF00501(AMP-binding) | 4 | LEU A 294PRO A 287VAL A 290ILE A 291 | None | 0.80A | 2aoiB-3o82A:undetectable | 2aoiB-3o82A:10.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obw | PROTEIN PELOTAHOMOLOG (Sulfolobussolfataricus) |
PF03463(eRF1_1)PF03465(eRF1_3) | 4 | LEU A 286PRO A 320VAL A 319ILE A 317 | None | 0.98A | 2aoiB-3obwA:undetectable | 2aoiB-3obwA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psg | PEPSINOGEN (Sus scrofa) |
PF00026(Asp)PF07966(A1_Propeptide) | 4 | LEU A 155ASP A 303VAL A 153ILE A 306 | None | 1.01A | 2aoiB-3psgA:5.5 | 2aoiB-3psgA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pwv | MHC CLASS I ANTIGEN (Bos taurus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | LEU A 246ASP A 226PRO A 249VAL A 248 | None | 0.95A | 2aoiB-3pwvA:undetectable | 2aoiB-3pwvA:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qq3 | MHC CLASS I ANTIGEN (Sus scrofa) |
PF00129(MHC_I)PF07654(C1-set) | 4 | LEU A 247ASP A 227PRO A 250VAL A 249 | None | 1.00A | 2aoiB-3qq3A:undetectable | 2aoiB-3qq3A:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rmt | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE 1 (Bacillushalodurans) |
PF00275(EPSP_synthase) | 4 | LEU A 257PRO A 22VAL A 21ILE A 19 | None | 0.86A | 2aoiB-3rmtA:undetectable | 2aoiB-3rmtA:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6c | PUTATIVE MAND FAMILYDEHYDRATASE (Pantoeaananatis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 342PRO A 368VAL A 377ILE A 122 | None | 1.00A | 2aoiB-3t6cA:undetectable | 2aoiB-3t6cA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tl2 | MALATE DEHYDROGENASE (Bacillusanthracis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | LEU A 270ASP A 128PRO A 254ILE A 256 | NoneSCN A 314 (-3.7A)NoneNone | 0.95A | 2aoiB-3tl2A:undetectable | 2aoiB-3tl2A:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr1 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Coxiellaburnetii) |
PF00275(EPSP_synthase) | 4 | LEU A 254PRO A 18VAL A 17ILE A 15 | None | 0.89A | 2aoiB-3tr1A:undetectable | 2aoiB-3tr1A:16.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ttp | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | None017 A 201 (-2.6A)017 A 201 (-4.1A)017 A 201 (-4.7A) | 0.19A | 2aoiB-3ttpA:19.4 | 2aoiB-3ttpA:76.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uhl | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81VAL A 82 | None | 0.59A | 2aoiB-3uhlA:15.9 | 2aoiB-3uhlA:80.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uvj | GUANYLATE CYCLASESOLUBLE SUBUNITALPHA-3 (Homo sapiens) |
PF00211(Guanylate_cyc) | 4 | LEU A 506PRO A 499VAL A 502ILE A 503 | None | 1.02A | 2aoiB-3uvjA:undetectable | 2aoiB-3uvjA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 4 | LEU A 913PRO A 906VAL A 909ILE A 910 | None | 0.96A | 2aoiB-3w9hA:undetectable | 2aoiB-3w9hA:7.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 4 | LEU A 912PRO A 905VAL A 908ILE A 909 | None | 0.93A | 2aoiB-3w9iA:undetectable | 2aoiB-3w9iA:6.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zw6 | RIBULOSEBISPHOSPHATECARBOXYLASE/OXYGENASE ACTIVASE 1,CHLOROPLASTIC (Nicotianatabacum) |
PF00004(AAA) | 4 | LEU A 97PRO A 103VAL A 102ILE A 100 | None | 0.84A | 2aoiB-3zw6A:undetectable | 2aoiB-3zw6A:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e8e | GLUTATHIONES-TRANSFERASE (Bombyx mori) |
PF13410(GST_C_2)PF13417(GST_N_3) | 4 | LEU A 102ASP A 99VAL A 159ILE A 98 | None | 0.97A | 2aoiB-4e8eA:undetectable | 2aoiB-4e8eA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f9d | POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINEN-DEACETYLASE (Escherichiacoli) |
PF01522(Polysacc_deac_1)PF14883(GHL13) | 4 | LEU A 590PRO A 543VAL A 544ILE A 545 | None | 1.00A | 2aoiB-4f9dA:undetectable | 2aoiB-4f9dA:10.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jr7 | CASEIN KINASE IISUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00069(Pkinase) | 4 | LEU A 210PRO A 198VAL A 201ILE A 203 | None | 0.95A | 2aoiB-4jr7A:undetectable | 2aoiB-4jr7A:13.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kt1 | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 4 (Homo sapiens) |
PF01462(LRRNT)PF13516(LRR_6)PF13855(LRR_8) | 4 | LEU A 72PRO A 52VAL A 51ILE A 69 | None | 0.94A | 2aoiB-4kt1A:undetectable | 2aoiB-4kt1A:10.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kx6 | FUMARATE REDUCTASESUBUNIT C (Escherichiacoli) |
PF02300(Fumarate_red_C) | 4 | LEU C 73PRO C 66VAL C 69ILE C 70 | None | 0.83A | 2aoiB-4kx6C:undetectable | 2aoiB-4kx6C:23.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4njv | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | NoneRIT A 500 (-2.4A)RIT A 500 (-3.9A)RIT A 500 (-4.3A) | 0.26A | 2aoiB-4njvA:20.3 | 2aoiB-4njvA:84.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4otu | GAMMA-GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
PF01019(G_glu_transpept) | 4 | LEU B 435PRO B 429VAL B 428ILE B 426 | None | 0.82A | 2aoiB-4otuB:undetectable | 2aoiB-4otuB:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6x | PHOSPHOLIPASE DSTSICTOX-BETAIC1 (Sicariusterrosus) |
no annotation | 4 | LEU A 257PRO A 250VAL A 253ILE A 254 | None | 0.97A | 2aoiB-4q6xA:undetectable | 2aoiB-4q6xA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qlj | BETA-GLUCOSIDASE 7 (Oryza sativa) |
PF00232(Glyco_hydro_1) | 4 | LEU A 435PRO A 463VAL A 452ILE A 451 | None | 0.95A | 2aoiB-4qljA:undetectable | 2aoiB-4qljA:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qlz | SJCHGC07024 PROTEIN (Schistosomajaponicum) |
PF00719(Pyrophosphatase) | 4 | LEU A 17PRO A 31VAL A 30ILE A 24 | None | 0.80A | 2aoiB-4qlzA:undetectable | 2aoiB-4qlzA:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5w | RIBULOSEBISPHOSPHATECARBOXYLASE/OXYGENASE ACTIVASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00004(AAA) | 4 | LEU A 94PRO A 100VAL A 99ILE A 97 | None | 0.83A | 2aoiB-4w5wA:undetectable | 2aoiB-4w5wA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xmm | NUCLEOPORIN NUP145 (Saccharomycescerevisiae) |
PF12110(Nup96) | 4 | LEU B 425PRO B 418VAL B 421ILE B 422 | None | 0.96A | 2aoiB-4xmmB:undetectable | 2aoiB-4xmmB:9.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y23 | GAMMA GLUTAMYLTRANSPEPTIDASE,GAMMA-GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
PF01019(G_glu_transpept) | 4 | LEU A 435PRO A 429VAL A 428ILE A 426 | None | 0.93A | 2aoiB-4y23A:undetectable | 2aoiB-4y23A:10.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yeh | LECTIN (Cicer arietinum) |
PF00045(Hemopexin) | 4 | LEU A 20PRO A 44VAL A 27ILE A 22 | None | 0.97A | 2aoiB-4yehA:undetectable | 2aoiB-4yehA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzr | POLYKETIDEBIOSYNTHESISCYTOCHROME P450 PKSS (Bacillussubtilis) |
PF00067(p450) | 4 | LEU A 157PRO A 150VAL A 153ILE A 154 | LEU A 157 ( 0.6A)PRO A 150 ( 1.1A)VAL A 153 ( 0.6A)ILE A 154 ( 0.7A) | 1.00A | 2aoiB-4yzrA:undetectable | 2aoiB-4yzrA:12.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hon | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF13385(Laminin_G_3) | 4 | LEU A 714PRO A 718VAL A 716ILE A 825 | None | 0.91A | 2aoiB-5honA:undetectable | 2aoiB-5honA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hp6 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF13385(Laminin_G_3)PF16369(GH43_C) | 4 | LEU A 714PRO A 718VAL A 716ILE A 825 | None | 0.89A | 2aoiB-5hp6A:undetectable | 2aoiB-5hp6A:8.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjq | AMP-DEPENDENTSYNTHETASE ANDLIGASE (Streptomycessp. ML694-90F3) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | LEU A 226PRO A 234VAL A 232ILE A 222 | None | 0.96A | 2aoiB-5jjqA:undetectable | 2aoiB-5jjqA:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdm | MAJOR TEGUMENTPROTEIN (Humangammaherpesvirus4) |
PF12818(Tegument_dsDNA) | 4 | LEU D 455PRO D 503VAL D 451ILE D 452 | None | 0.94A | 2aoiB-5kdmD:undetectable | 2aoiB-5kdmD:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koa | CELL DIVISIONPROTEIN ZAPD (Escherichiacoli) |
PF07072(ZapD) | 4 | LEU A 112ASP A 115VAL A 47ILE A 118 | None | 0.81A | 2aoiB-5koaA:undetectable | 2aoiB-5koaA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5liv | CYTOCHROME P450CYP260A1,CYTOCHROMEP450 CYP260A1 (Sorangiumcellulosum) |
PF00067(p450) | 4 | LEU A 190PRO A 183VAL A 186ILE A 187 | None | 1.02A | 2aoiB-5livA:undetectable | 2aoiB-5livA:14.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5loi | RAD26 (Thermothelomycesthermophila) |
PF12331(DUF3636) | 4 | ASP A 439PRO A 481VAL A 482ILE A 438 | None | 0.99A | 2aoiB-5loiA:undetectable | 2aoiB-5loiA:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5msz | THERMOBIA DOMESTICADOMESTICA AA15 (Thermobiadomestica) |
no annotation | 4 | LEU A 143PRO A 7VAL A 83ILE A 81 | None | 0.90A | 2aoiB-5mszA:undetectable | 2aoiB-5mszA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nks | DIHYDROPYRIMIDINASE-RELATED PROTEIN 4 (Homo sapiens) |
no annotation | 4 | LEU A 49PRO A 52VAL A 51ILE A 50 | LEU A 49 ( 0.6A)PRO A 52 ( 1.1A)VAL A 51 ( 0.6A)ILE A 50 ( 0.6A) | 1.01A | 2aoiB-5nksA:undetectable | 2aoiB-5nksA:9.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5t2z | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | None | 0.26A | 2aoiB-5t2zA:20.2 | 2aoiB-5t2zA:80.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDG (Methanothermobacterwolfeii) |
PF12838(Fer4_7) | 4 | LEU G 60PRO G 23VAL G 24ILE G 45 | NoneNoneNoneSF4 G 102 ( 3.9A) | 1.02A | 2aoiB-5t5iG:undetectable | 2aoiB-5t5iG:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyw | PYRUVATE CARBOXYLASE (Lactococcuslactis) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | LEU A 527PRO A 769VAL A 757ILE A 755 | None | 1.00A | 2aoiB-5vywA:undetectable | 2aoiB-5vywA:6.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wka | BETA-GLUCOSIDASE (metagenome) |
no annotation | 4 | LEU A 418PRO A 446VAL A 435ILE A 434 | None | 0.95A | 2aoiB-5wkaA:undetectable | 2aoiB-5wkaA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zln | TOLL-LIKE RECEPTOR 9 (Mus musculus) |
no annotation | 4 | LEU A 78PRO A 54VAL A 53ILE A 75 | None | 1.01A | 2aoiB-5zlnA:undetectable | 2aoiB-5zlnA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxa | TOLL-LIKE RECEPTOR5B, VARIABLELYMPHOCYTE RECEPTORB CHIMERA (Danio rerio;Eptatretusburgeri) |
no annotation | 4 | LEU A 62PRO A 43VAL A 42ILE A 59 | None | 1.00A | 2aoiB-6bxaA:undetectable | 2aoiB-6bxaA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d4j | PROTEIN PATCHEDHOMOLOG 1 (Homo sapiens) |
no annotation | 4 | LEU A 777PRO A 782VAL A 781ILE A 780 | None | 0.95A | 2aoiB-6d4jA:undetectable | 2aoiB-6d4jA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6en4 | SPLICING FACTOR 3BSUBUNIT 3 (Homo sapiens) |
no annotation | 4 | LEU A 249PRO A 239VAL A 238ILE A 236 | None | 0.96A | 2aoiB-6en4A:undetectable | 2aoiB-6en4A:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f85 | CYTOCHROME P450CYP260A1 (Sorangiumcellulosum) |
no annotation | 4 | LEU A 140PRO A 133VAL A 136ILE A 137 | None | 1.01A | 2aoiB-6f85A:undetectable | 2aoiB-6f85A:19.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6upj | HIV-2 PROTEASE (Humanimmunodeficiencyvirus 2) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | NoneNIU A 100 (-2.8A)NoneNone | 0.50A | 2aoiB-6upjA:17.8 | 2aoiB-6upjA:49.49 |