SIMILAR PATTERNS OF AMINO ACIDS FOR 2AOF_C_FRDC305_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aoa | T-FIMBRIN (Homo sapiens) |
PF00307(CH) | 4 | LEU A 306PRO A 311ALA A 310ILE A 309 | LEU A 306 ( 0.6A)PRO A 311 ( 1.1A)ALA A 310 ( 0.0A)ILE A 309 ( 0.3A) | 0.90A | 2aofB-1aoaA:undetectable | 2aofB-1aoaA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b0a | PROTEIN (FOLDBIFUNCTIONALPROTEIN) (Escherichiacoli) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | LEU A 86ASP A 89ALA A 37ILE A 92 | None | 0.93A | 2aofB-1b0aA:undetectable | 2aofB-1b0aA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cf5 | PROTEIN(BETA-MOMORCHARIN) (Momordicacharantia) |
PF00161(RIP) | 4 | LEU A 186PRO A 216ALA A 182ILE A 183 | None | 1.03A | 2aofB-1cf5A:undetectable | 2aofB-1cf5A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ct5 | PROTEIN (YEASTHYPOTHETICALPROTEIN, SELENOMET) (Saccharomycescerevisiae) |
PF01168(Ala_racemase_N) | 4 | LEU A 81PRO A 52ALA A 53ILE A 5 | None | 1.02A | 2aofB-1ct5A:undetectable | 2aofB-1ct5A:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gm5 | RECG (Thermotogamaritima) |
PF00270(DEAD)PF00271(Helicase_C)PF17190(RecG_N)PF17191(RecG_wedge) | 4 | LEU A 633PRO A 656ALA A 636ILE A 653 | None | 1.05A | 2aofB-1gm5A:undetectable | 2aofB-1gm5A:8.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg3 | TRIOSEPHOSPHATEISOMERASE (Pyrococcuswoesei) |
PF00121(TIM)PF05690(ThiG) | 4 | LEU A 221PRO A 214ALA A 217ILE A 218 | None | 1.01A | 2aofB-1hg3A:undetectable | 2aofB-1hg3A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htq | GLUTAMINE SYNTHETASE (Mycobacteriumtuberculosis) |
PF00120(Gln-synt_C)PF03951(Gln-synt_N) | 4 | LEU A 421PRO A 314ALA A 310ILE A 418 | None | 0.93A | 2aofB-1htqA:undetectable | 2aofB-1htqA:11.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | A79 A 800 ( 3.8A)A79 A 800 (-2.7A)A79 A 800 ( 3.9A)A79 A 800 (-3.6A) | 0.55A | 2aofB-1hvcA:13.9 | 2aofB-1hvcA:46.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | A79 A 800 ( 4.0A)A79 A 800 (-2.8A)A79 A 800 ( 3.4A)A79 A 800 (-3.8A) | 0.38A | 2aofB-1hvcA:13.9 | 2aofB-1hvcA:46.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | LEU A 90PRO A 83ALA A 86ILE A 87 | None | 0.87A | 2aofB-1l5jA:undetectable | 2aofB-1l5jA:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mor | GLUCOSAMINE6-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF01380(SIS) | 4 | LEU A 486PRO A 515ALA A 467ILE A 492 | None | 0.93A | 2aofB-1morA:undetectable | 2aofB-1morA:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd1 | PROTEIN TRANSPORTPROTEIN SEC24 (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 4 | LEU A 616PRO A 293ALA A 292ILE A 626 | None | 1.00A | 2aofB-1pd1A:undetectable | 2aofB-1pd1A:8.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pss | PHOTOSYNTHETICREACTION CENTER (Rhodobactersphaeroides) |
PF00124(Photo_RC) | 4 | LEU L 246PRO L 171ALA L 172ILE L 250 | None | 0.92A | 2aofB-1pssL:undetectable | 2aofB-1pssL:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sgv | TRNA PSEUDOURIDINESYNTHASE B (Mycobacteriumtuberculosis) |
PF01509(TruB_N)PF09142(TruB_C)PF16198(TruB_C_2) | 4 | ASP A 268PRO A 292ALA A 250ILE A 274 | None | 1.04A | 2aofB-1sgvA:undetectable | 2aofB-1sgvA:18.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | None | 0.44A | 2aofB-1sivA:18.5 | 2aofB-1sivA:51.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wle | SERYL-TRNASYNTHETASE (Bos taurus) |
PF00587(tRNA-synt_2b) | 4 | LEU A 57ASP A 58PRO A 50ALA A 53 | None | 0.94A | 2aofB-1wleA:undetectable | 2aofB-1wleA:11.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xiu | RXR-LIKE PROTEIN (Biomphalariaglabrata) |
PF00104(Hormone_recep) | 4 | LEU A 274ASP A 270ALA A 354ILE A 273 | None | 0.99A | 2aofB-1xiuA:undetectable | 2aofB-1xiuA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ym5 | HYPOTHETICAL 32.6KDA PROTEIN INDAP2-SLT2 INTERGENICREGION (Saccharomycescerevisiae) |
PF02567(PhzC-PhzF) | 4 | LEU A 197PRO A 153ALA A 165ILE A 195 | None | 0.87A | 2aofB-1ym5A:undetectable | 2aofB-1ym5A:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z5x | ULTRASPIRACLEPROTEIN (USP) AHOMOLOGUE OF RXR (Bemisia tabaci) |
PF00104(Hormone_recep) | 4 | LEU U 335ASP U 331ALA U 415ILE U 334 | None | 0.93A | 2aofB-1z5xU:undetectable | 2aofB-1z5xU:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zap | SECRETED ASPARTICPROTEINASE (Candidaalbicans) |
PF00026(Asp) | 4 | LEU A 216ASP A 218ALA A 303ILE A 305 | NoneA70 A 500 ( 2.3A)A70 A 500 ( 3.8A)A70 A 500 (-4.8A) | 0.81A | 2aofB-1zapA:6.8 | 2aofB-1zapA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zel | HYPOTHETICAL PROTEINRV2827C (Mycobacteriumtuberculosis) |
PF09407(AbiEi_1)PF13338(AbiEi_4) | 4 | LEU A 55PRO A 48ALA A 51ILE A 52 | None | 1.03A | 2aofB-1zelA:undetectable | 2aofB-1zelA:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkd | DUF185 (Rhodopseudomonaspalustris) |
PF02636(Methyltransf_28) | 4 | LEU A 225ASP A 221ALA A 228ILE A 224 | None | 0.78A | 2aofB-1zkdA:undetectable | 2aofB-1zkdA:14.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cja | SERYL-TRNASYNTHETASE (Methanosarcinabarkeri) |
no annotation | 4 | LEU A 111PRO A 106ALA A 107ILE A 129 | None | 0.98A | 2aofB-2cjaA:undetectable | 2aofB-2cjaA:12.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fmb | EQUINE INFECTIOUSANEMIA VIRUSPROTEASE (Equineinfectiousanemia virus) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 86ILE A 89 | NoneLP1 A 201 (-2.3A)LP1 A 201 (-3.9A)LP1 A 201 (-4.2A) | 0.45A | 2aofB-2fmbA:14.9 | 2aofB-2fmbA:33.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gl8 | RETINOIC ACIDRECEPTOR RXR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 4 | LEU A 79ASP A 75ALA A 159ILE A 78 | None | 0.93A | 2aofB-2gl8A:undetectable | 2aofB-2gl8A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpg | ABC TRANSPORTER,PERIPLASMICSUBSTRATE-BINDINGPROTEIN (Thermotogamaritima) |
PF03480(DctP) | 4 | LEU A 123PRO A 116ALA A 119ILE A 120 | None | 0.96A | 2aofB-2hpgA:undetectable | 2aofB-2hpgA:14.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mux | UBIQUITINCARBOXYL-TERMINALHYDROLASE 25 (Homo sapiens) |
PF02809(UIM) | 4 | LEU A 36ASP A 32ALA A 39ILE A 35 | None | 1.05A | 2aofB-2muxA:undetectable | 2aofB-2muxA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlx | XYLULOSE KINASE (Escherichiacoli) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | ASP A 98PRO A 92ALA A 93ILE A 94 | None | 0.92A | 2aofB-2nlxA:undetectable | 2aofB-2nlxA:11.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o5p | FERRIPYOVERDINERECEPTOR (Pseudomonasaeruginosa) |
PF00593(TonB_dep_Rec)PF07660(STN)PF07715(Plug) | 4 | LEU A 98PRO A 91ALA A 94ILE A 95 | None | 0.90A | 2aofB-2o5pA:undetectable | 2aofB-2o5pA:8.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pet | LUTHERAN BLOOD GROUPGLYCOPROTEIN (Homo sapiens) |
PF07686(V-set)PF08205(C2-set_2) | 4 | LEU A 191PRO A 123ALA A 139ILE A 138 | None | 0.83A | 2aofB-2petA:undetectable | 2aofB-2petA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qo3 | ERYAII ERYTHROMYCINPOLYKETIDE SYNTHASEMODULES 3 AND 4 (Saccharopolysporaerythraea) |
PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | LEU A 353ASP A 354PRO A 346ALA A 349 | None | 1.02A | 2aofB-2qo3A:undetectable | 2aofB-2qo3A:8.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qps | ALPHA-AMYLASE TYPE AISOZYME (Hordeum vulgare) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 4 | LEU A 354PRO A 273ALA A 272ILE A 356 | None | 0.99A | 2aofB-2qpsA:undetectable | 2aofB-2qpsA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzw | CANDIDAPEPSIN-1 (Candidaalbicans) |
PF00026(Asp) | 4 | LEU A 216ASP A 218ALA A 303ILE A 305 | None | 0.85A | 2aofB-2qzwA:7.6 | 2aofB-2qzwA:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r8a | LONG-CHAIN FATTYACID TRANSPORTPROTEIN (Escherichiacoli) |
PF03349(Toluene_X) | 4 | LEU A 184PRO A 174ALA A 175ILE A 170 | None | 1.03A | 2aofB-2r8aA:undetectable | 2aofB-2r8aA:12.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rkf | PROTEASE RETROPEPSIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | LEU A 23ASP A 25PRO A 81ALA A 82ILE A 84 | NoneAB1 A 501 (-2.4A)AB1 A 501 (-4.2A)AB1 A 501 (-3.6A)AB1 A 501 ( 4.2A) | 0.46A | 2aofB-2rkfA:20.6 | 2aofB-2rkfA:83.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v8n | LACTOSE PERMEASE (Escherichiacoli) |
PF01306(LacY_symp) | 4 | LEU A 76PRO A 123ALA A 124ILE A 80 | None | 0.76A | 2aofB-2v8nA:undetectable | 2aofB-2v8nA:12.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y5j | DIHYDROPTEROATESYNTHASE (Burkholderiacenocepacia) |
PF00809(Pterin_bind) | 4 | LEU A 22PRO A 225ALA A 265ILE A 266 | None | 0.99A | 2aofB-2y5jA:undetectable | 2aofB-2y5jA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ynk | WZI (Escherichiacoli) |
PF14052(Caps_assemb_Wzi) | 4 | LEU A 64PRO A 69ALA A 67ILE A 46 | None | 1.05A | 2aofB-2ynkA:undetectable | 2aofB-2ynkA:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z9v | ASPARTATEAMINOTRANSFERASE (Mesorhizobiumloti) |
PF00266(Aminotran_5) | 4 | LEU A 362PRO A 355ALA A 358ILE A 359 | None | 0.91A | 2aofB-2z9vA:undetectable | 2aofB-2z9vA:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abb | CYTOCHROME P450HYDROXYLASE (Streptomycesavermitilis) |
PF00067(p450) | 4 | LEU A 161PRO A 154ALA A 157ILE A 158 | None | 1.01A | 2aofB-3abbA:undetectable | 2aofB-3abbA:13.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgh | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF12741(SusD-like) | 4 | LEU A 521ASP A 525ALA A 516ILE A 517 | None | 0.89A | 2aofB-3cghA:undetectable | 2aofB-3cghA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eyb | NUCLEAR HORMONERECEPTOR RXR (Branchiostomafloridae) |
PF00104(Hormone_recep) | 4 | LEU A 329ASP A 325ALA A 409ILE A 328 | None | 1.04A | 2aofB-3eybA:undetectable | 2aofB-3eybA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fay | RASGTPASE-ACTIVATING-LIKE PROTEIN IQGAP1 (Homo sapiens) |
PF00616(RasGAP) | 4 | LEU A1072PRO A1198ALA A1199ILE A1200 | None | 0.99A | 2aofB-3fayA:undetectable | 2aofB-3fayA:13.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd5 | SELENIDE, WATERDIKINASE 1 (Homo sapiens) |
PF00586(AIRS)PF02769(AIRS_C) | 4 | LEU A 324ASP A 265PRO A 188ALA A 263 | None MG A 395 (-2.6A)NoneNone | 0.93A | 2aofB-3fd5A:undetectable | 2aofB-3fd5A:13.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgq | NEUROSERPIN (Homo sapiens) |
PF00079(Serpin) | 4 | LEU A 29PRO A 22ALA A 25ILE A 26 | None | 0.92A | 2aofB-3fgqA:undetectable | 2aofB-3fgqA:12.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fho | ATP-DEPENDENT RNAHELICASE DBP5 (Schizosaccharomycespombe) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | LEU A 291PRO A 309ALA A 308ILE A 157 | None | 1.05A | 2aofB-3fhoA:undetectable | 2aofB-3fhoA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzs | UNCHARACTERIZED SUSDSUPERFAMILY PROTEIN (Bacteroidesfragilis) |
PF12741(SusD-like) | 4 | LEU A 525ASP A 529ALA A 520ILE A 521 | None | 0.84A | 2aofB-3gzsA:undetectable | 2aofB-3gzsA:10.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k0t | ENDORIBONUCLEASEL-PSP, PUTATIVE (Pseudomonassyringae groupgenomosp. 3) |
PF01042(Ribonuc_L-PSP) | 4 | LEU A 123ASP A 71ALA A 65ILE A 125 | None | 1.05A | 2aofB-3k0tA:undetectable | 2aofB-3k0tA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lr1 | TUNGSTATE ABCTRANSPORTER,PERIPLASMICTUNGSTATE-BINDINGPROTEIN (Geobactersulfurreducens) |
PF12849(PBP_like_2) | 4 | LEU A 108PRO A 92ALA A 93ILE A 95 | None | 1.03A | 2aofB-3lr1A:undetectable | 2aofB-3lr1A:22.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mws | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | None | 0.26A | 2aofB-3mwsA:19.7 | 2aofB-3mwsA:78.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzp | ARGININEDECARBOXYLASE (Campylobacterjejuni) |
PF02784(Orn_Arg_deC_N) | 4 | LEU A 332PRO A 335ALA A 334ILE A 333 | None | 1.03A | 2aofB-3nzpA:undetectable | 2aofB-3nzpA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE ALPHA-SUBUNIT (Komagataellapastoris) |
PF00365(PFK) | 4 | LEU A 724PRO A 615ALA A 616ILE A 695 | None | 0.98A | 2aofB-3opyA:undetectable | 2aofB-3opyA:7.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qo7 | SERYL-TRNASYNTHETASE,CYTOPLASMIC (Candidaalbicans) |
PF00587(tRNA-synt_2b)PF02403(Seryl_tRNA_N) | 4 | LEU A 405PRO A 206ALA A 272ILE A 301 | None | 0.74A | 2aofB-3qo7A:undetectable | 2aofB-3qo7A:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3svl | PROTEIN YIEF (Escherichiacoli) |
PF03358(FMN_red) | 4 | LEU A 27PRO A 32ALA A 31ILE A 30 | None | 1.00A | 2aofB-3svlA:undetectable | 2aofB-3svlA:23.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t3c | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ALA A 82 | SO4 A 101 (-4.2A)017 A 201 (-2.6A)NoneSO4 A 101 (-3.5A) | 0.59A | 2aofB-3t3cA:18.3 | 2aofB-3t3cA:75.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5t | PUTATIVEGLYCOSYLTRANSFERASE (Streptomyceshygroscopicus) |
PF00982(Glyco_transf_20) | 4 | LEU A 179PRO A 208ALA A 209ILE A 212 | None | 0.95A | 2aofB-3t5tA:undetectable | 2aofB-3t5tA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tox | SHORT CHAINDEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | LEU A 86PRO A 130ALA A 131ILE A 132 | None | 1.00A | 2aofB-3toxA:undetectable | 2aofB-3toxA:18.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ttp | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | None017 A 201 (-2.6A)017 A 201 (-4.1A)017 A 201 (-4.7A) | 0.17A | 2aofB-3ttpA:19.4 | 2aofB-3ttpA:76.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9p | THYMIDYLATE KINASE (Burkholderiathailandensis) |
PF02223(Thymidylate_kin) | 4 | LEU A 136ASP A 138ALA A 176ILE A 185 | NoneNoneNoneGOL A 252 (-3.8A) | 0.97A | 2aofB-3v9pA:undetectable | 2aofB-3v9pA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vlb | XYLOGLUCAN-SPECIFICENDO-BETA-1,4-GLUCANASE A (Aspergillusaculeatus) |
PF01670(Glyco_hydro_12) | 4 | LEU B 127PRO B 206ALA B 100ILE B 98 | None | 1.01A | 2aofB-3vlbB:undetectable | 2aofB-3vlbB:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wn6 | ALPHA-AMYLASE (Oryza sativa) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 4 | LEU A 377PRO A 296ALA A 295ILE A 379 | None | 0.92A | 2aofB-3wn6A:undetectable | 2aofB-3wn6A:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bev | COPPER EFFLUX ATPASE (Legionellapneumophila) |
PF00122(E1-E2_ATPase)PF00702(Hydrolase) | 4 | LEU A 682PRO A 391ALA A 389ILE A 678 | None | 1.03A | 2aofB-4bevA:undetectable | 2aofB-4bevA:9.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bpt | PHENYLALANINE-4-HYDROXYLASE (PAH)(PHE-4-MONOOXYGENASE) (Legionellapneumophila) |
PF00351(Biopterin_H) | 4 | LEU A 124PRO A 81ALA A 102ILE A 120 | None | 1.01A | 2aofB-4bptA:undetectable | 2aofB-4bptA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btg | MAJOR INNER PROTEINP1 (Pseudomonasvirus phi6) |
no annotation | 4 | LEU A 462PRO A 455ALA A 458ILE A 459 | None | 0.81A | 2aofB-4btgA:undetectable | 2aofB-4btgA:9.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dhg | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Thermobisporabispora) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 313PRO A 336ALA A 337ILE A 338 | None | 1.02A | 2aofB-4dhgA:undetectable | 2aofB-4dhgA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fai | CG5976, ISOFORM B (Drosophilamelanogaster) |
PF04389(Peptidase_M28) | 4 | LEU A 72PRO A 157ALA A 155ILE A 68 | None | 0.86A | 2aofB-4faiA:undetectable | 2aofB-4faiA:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hs4 | CHROMATE REDUCTASE (Komagataeibacterhansenii) |
PF03358(FMN_red) | 4 | LEU A 29PRO A 34ALA A 33ILE A 32 | None | 0.92A | 2aofB-4hs4A:undetectable | 2aofB-4hs4A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i93 | PROBABLESERINE/THREONINE-PROTEIN KINASEAT5G41260 (Arabidopsisthaliana) |
PF07714(Pkinase_Tyr) | 4 | LEU A 268PRO A 253ALA A 256ILE A 260 | None | 0.93A | 2aofB-4i93A:undetectable | 2aofB-4i93A:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jkw | BUTYROPHILINSUBFAMILY 3 MEMBERA1 (Homo sapiens) |
PF07686(V-set) | 4 | LEU A 73ASP A 75PRO A 24ALA A 83 | None | 0.94A | 2aofB-4jkwA:undetectable | 2aofB-4jkwA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l9a | PUTATIVEUNCHARACTERIZEDPROTEIN SMU.1393C (Streptococcusmutans) |
no annotation | 4 | LEU A 30PRO A 61ALA A 60ILE A 58 | None | 0.97A | 2aofB-4l9aA:undetectable | 2aofB-4l9aA:12.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4njv | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | NoneRIT A 500 (-2.4A)RIT A 500 (-3.9A)RIT A 500 (-4.3A) | 0.35A | 2aofB-4njvA:20.1 | 2aofB-4njvA:84.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4npr | XYLOGLUCAN-SPECIFICENDO-BETA-1,4-GLUCANASE GH12 (Aspergillusniveus) |
PF01670(Glyco_hydro_12) | 4 | LEU A 141PRO A 220ALA A 114ILE A 112 | None | 0.93A | 2aofB-4nprA:undetectable | 2aofB-4nprA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oiy | PROTEIN TRANSPORTPROTEIN SEC7 (Saccharomycescerevisiae) |
PF01369(Sec7) | 4 | LEU A 849PRO A 842ALA A 845ILE A 846 | None | 0.87A | 2aofB-4oiyA:undetectable | 2aofB-4oiyA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pdx | PUTATIVEALKYL/ARYL-SULFATASEYJCS (Escherichiacoli) |
PF00753(Lactamase_B)PF14863(Alkyl_sulf_dimr)PF14864(Alkyl_sulf_C) | 4 | LEU A 161ASP A 162PRO A 154ALA A 157 | None | 1.03A | 2aofB-4pdxA:undetectable | 2aofB-4pdxA:10.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q3r | ARGINASE (Schistosomamansoni) |
PF00491(Arginase) | 4 | LEU A 63PRO A 123ALA A 24ILE A 61 | None | 1.02A | 2aofB-4q3rA:undetectable | 2aofB-4q3rA:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rsi | STRUCTURALMAINTENANCE OFCHROMOSOMES PROTEIN4 (Saccharomycescerevisiae) |
PF06470(SMC_hinge) | 4 | LEU B 692ASP B 715ALA B 778ILE B 742 | None | 0.82A | 2aofB-4rsiB:undetectable | 2aofB-4rsiB:13.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w7h | CARBONYL REDUCTASE (Sphingomonassp. A1) |
PF13561(adh_short_C2) | 4 | LEU A 249PRO A 230ALA A 231ILE A 251 | None | 0.89A | 2aofB-4w7hA:undetectable | 2aofB-4w7hA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yt2 | H(2)-FORMINGMETHYLENETETRAHYDROMETHANOPTERINDEHYDROGENASE-RELATED PROTEIN MJ1338 (Methanocaldococcusjannaschii) |
PF03201(HMD) | 4 | ASP A 86PRO A 101ALA A 105ILE A 109 | None | 0.96A | 2aofB-4yt2A:undetectable | 2aofB-4yt2A:14.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b8h | TYPE IIIPANTOTHENATE KINASE (Burkholderiacenocepacia) |
PF03309(Pan_kinase) | 4 | LEU A 251ASP A 9ALA A 108ILE A 247 | None | 1.00A | 2aofB-5b8hA:undetectable | 2aofB-5b8hA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d91 | AF2299PROTEIN,PHOSPHATIDYLINOSITOL SYNTHASE (Archaeoglobusfulgidus;Renibacteriumsalmoninarum) |
PF01066(CDP-OH_P_transf) | 4 | LEU A 120PRO A 113ALA A 116ILE A 117 | NoneNoneNone8K6 A 305 ( 4.1A) | 1.03A | 2aofB-5d91A:undetectable | 2aofB-5d91A:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqn | CYTOCHROME P450CYP125 (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 4 | LEU A 165PRO A 158ALA A 161ILE A 162 | None | 1.05A | 2aofB-5dqnA:undetectable | 2aofB-5dqnA:13.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5egl | ACYL COA HYDROLASE (Staphylococcusaureus) |
PF03061(4HBT) | 4 | LEU A 78ASP A 76ALA A 111ILE A 100 | None | 0.98A | 2aofB-5eglA:undetectable | 2aofB-5eglA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eq6 | TYPE 4 FIMBRIALBIOGENESIS PROTEINPILM (Pseudomonasaeruginosa) |
PF11104(PilM_2) | 4 | LEU A 348ASP A 16ALA A 174ILE A 344 | None | 0.97A | 2aofB-5eq6A:undetectable | 2aofB-5eq6A:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fub | PROTEIN ARGININEMETHYLTRANSFERASE 2 (Danio rerio) |
PF13649(Methyltransf_25) | 4 | LEU A 136PRO A 139ALA A 137ILE A 107 | CL A1409 ( 4.9A)NoneNoneNone | 1.04A | 2aofB-5fubA:undetectable | 2aofB-5fubA:13.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gui | CHAPERONE PROTEINCLPC1, CHLOROPLASTIC (Arabidopsisthaliana) |
PF02861(Clp_N) | 4 | LEU A 220PRO A 224ALA A 222ILE A 147 | None | 1.05A | 2aofB-5guiA:undetectable | 2aofB-5guiA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5x | PUTATIVEOXIDOREDUCTASE (Streptomycescoelicolor) |
PF13561(adh_short_C2) | 4 | LEU A 97PRO A 141ALA A 142ILE A 143 | None | 0.89A | 2aofB-5h5xA:undetectable | 2aofB-5h5xA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdt | SISTER CHROMATIDCOHESION PROTEINPDS5 HOMOLOG B (Homo sapiens) |
no annotation | 4 | LEU A 605PRO A 610ALA A 609ILE A 608 | None | 1.00A | 2aofB-5hdtA:undetectable | 2aofB-5hdtA:6.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hqw | PUTATIVE POLYKETIDESYNTHASE (Brevibacillusbrevis) |
PF14765(PS-DH) | 4 | LEU A2348ASP A2479ALA A2347ILE A2487 | None | 1.01A | 2aofB-5hqwA:undetectable | 2aofB-5hqwA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jvf | SITE-DETERMININGPROTEIN (Pseudomonasaeruginosa) |
PF10609(ParA) | 4 | LEU A 44ASP A 46PRO A 84ILE A 89 | None | 1.00A | 2aofB-5jvfA:undetectable | 2aofB-5jvfA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m60 | BETA-1,3-GLUCANASE (Chaetomiumthermophilum) |
PF12708(Pectate_lyase_3) | 4 | LEU A 99PRO A 471ALA A 469ILE A 55 | None | 1.01A | 2aofB-5m60A:undetectable | 2aofB-5m60A:9.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8o | DNA HELICASE I (Escherichiacoli) |
PF07057(TraI)PF08751(TrwC)PF13604(AAA_30) | 4 | LEU A 814PRO A 567ALA A 568ILE A 570 | None | 0.97A | 2aofB-5n8oA:undetectable | 2aofB-5n8oA:4.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5t2z | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | None | 0.22A | 2aofB-5t2zA:20.2 | 2aofB-5t2zA:80.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uqj | U6 SNRNAPHOSPHODIESTERASE (Saccharomycescerevisiae) |
PF09749(HVSL) | 4 | LEU A 188PRO A 120ALA A 235ILE A 234 | None | 0.96A | 2aofB-5uqjA:undetectable | 2aofB-5uqjA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uy7 | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Burkholderiaambifaria) |
PF00905(Transpeptidase) | 4 | LEU A 337ASP A 338ALA A 414ILE A 411 | NoneSO4 A 704 ( 4.6A)NoneNone | 1.02A | 2aofB-5uy7A:undetectable | 2aofB-5uy7A:11.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vni | PROTEIN TRANSPORTPROTEIN SEC24A (Homo sapiens) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 4 | LEU B 808PRO B 493ALA B 492ILE B 818 | None | 1.04A | 2aofB-5vniB:undetectable | 2aofB-5vniB:9.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfa | NAD-REDUCINGHYDROGENASE (Hydrogenophilusthermoluteolus) |
PF00374(NiFeSe_Hases) | 4 | LEU D 399PRO D 395ALA D 394ILE D 392 | FCO D 501 (-3.3A)FCO D 501 ( 3.8A)FCO D 501 (-3.6A)None | 0.98A | 2aofB-5xfaD:undetectable | 2aofB-5xfaD:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6g | FLAGELLAR BRAKEPROTEIN YCGR (Escherichiacoli) |
no annotation | 4 | LEU A 146PRO A 122ALA A 121ILE A 119 | None | 0.83A | 2aofB-5y6gA:undetectable | 2aofB-5y6gA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6coy | CHLORIDE CHANNELPROTEIN 1 (Homo sapiens) |
no annotation | 4 | LEU A 173PRO A 478ALA A 176ILE A 172 | None | 0.95A | 2aofB-6coyA:undetectable | 2aofB-6coyA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fbt | LYTIC MUREINTRANSGLYCOSYLASE (Pseudomonasaeruginosa) |
no annotation | 4 | LEU A 260ASP A 261PRO A 253ALA A 256 | None | 0.98A | 2aofB-6fbtA:undetectable | 2aofB-6fbtA:19.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6upj | HIV-2 PROTEASE (Humanimmunodeficiencyvirus 2) |
PF00077(RVP) | 4 | LEU A 23ASP A 25PRO A 81ILE A 84 | NoneNIU A 100 (-2.8A)NoneNone | 0.47A | 2aofB-6upjA:17.8 | 2aofB-6upjA:49.49 |