SIMILAR PATTERNS OF AMINO ACIDS FOR 2ACL_C_REAC503_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1akm | ORNITHINETRANSCARBAMYLASE (Escherichiacoli) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | ALA A 65ALA A 66GLN A 69ASN A 46ILE A 103 | None | 1.02A | 2aclC-1akmA:undetectable | 2aclC-1akmA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dci | DIENOYL-COAISOMERASE (Rattusnorvegicus) |
PF00378(ECH_1) | 5 | ILE A 166ALA A 190GLN A 188ALA A 233ILE A 163 | None | 1.06A | 2aclC-1dciA:undetectable | 2aclC-1dciA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | ALA B 185ALA B 186ASN B 192PHE B 139ILE B 216 | None | 1.17A | 2aclC-1e9yB:0.0 | 2aclC-1e9yB:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1egz | ENDOGLUCANASE Z (Dickeyachrysanthemi) |
PF00150(Cellulase) | 5 | ALA A 117GLN A 114PHE A 113ALA A 153ILE A 94 | None | 1.18A | 2aclC-1egzA:undetectable | 2aclC-1egzA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i4e | CASPASE-8 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | ASN B2240PHE B2244ARG B2248ALA B2245ILE B2323 | None | 1.02A | 2aclC-1i4eB:undetectable | 2aclC-1i4eB:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7h | ALKALINE PHOSPHATASE (Pandalusborealis) |
PF00245(Alk_phosphatase) | 5 | ILE A 350ALA A 28GLN A 27ARG A 137ILE A 458 | None | 1.13A | 2aclC-1k7hA:undetectable | 2aclC-1k7hA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lfb | LIVER TRANSCRIPTIONFACTOR (LFB1) (Rattusnorvegicus) |
PF00046(Homeobox) | 5 | PHE A 78ARG A 82ALA A 79ILE A 23CYH A 46 | None | 0.92A | 2aclC-1lfbA:undetectable | 2aclC-1lfbA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nmo | HYPOTHETICAL PROTEINYBGI (Escherichiacoli) |
PF01784(NIF3) | 5 | ILE A 179ALA A 182ALA A 183ALA A 169ILE A 200 | None | 0.88A | 2aclC-1nmoA:undetectable | 2aclC-1nmoA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ort | ORNITHINETRANSCARBAMOYLASE (Pseudomonasaeruginosa) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | ALA A 66ALA A 67GLN A 70ASN A 47ILE A 104 | None | 0.93A | 2aclC-1ortA:undetectable | 2aclC-1ortA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qdu | CASPASE-8ALPHA-CHAIN (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | ASN A 169PHE A 173ARG A 175ALA A 174ILE A 243 | None | 1.07A | 2aclC-1qduA:undetectable | 2aclC-1qduA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ufl | NITROGEN REGULATORYPROTEIN P-II (Thermusthermophilus) |
PF00543(P-II) | 5 | ILE A 77ALA A 76ALA A 19ASN A 14ALA A 23 | None | 1.18A | 2aclC-1uflA:undetectable | 2aclC-1uflA:20.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uhl | RETINOIC ACIDRECEPTOR RXR-BETA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | ILE A 339ALA A 342ALA A 343GLN A 346ASN A 377PHE A 384ARG A 387ALA A 398ILE A 416CYH A 503 | MEI A1001 (-3.8A)MEI A1001 (-3.1A)MEI A1001 (-3.3A)NoneNoneMEI A1001 (-4.5A)MEI A1001 (-3.6A)MEI A1001 (-3.4A)NoneMEI A1001 (-4.0A) | 0.83A | 2aclC-1uhlA:30.2 | 2aclC-1uhlA:88.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1up4 | 6-PHOSPHO-BETA-GLUCOSIDASE (Thermotogamaritima) |
PF02056(Glyco_hydro_4)PF11975(Glyco_hydro_4C) | 5 | ILE A 6ALA A 4ALA A 68ALA A 72ILE A 119 | None | 1.14A | 2aclC-1up4A:undetectable | 2aclC-1up4A:19.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xiu | RXR-LIKE PROTEIN (Biomphalariaglabrata) |
PF00104(Hormone_recep) | 10 | ILE A 242ALA A 245ALA A 246GLN A 249ASN A 280PHE A 287ARG A 290ALA A 301ILE A 319CYH A 406 | 9CR A 201 ( 4.4A)9CR A 201 (-3.6A)9CR A 201 (-3.6A)9CR A 201 (-4.1A)None9CR A 201 (-4.7A)9CR A 201 (-2.8A)9CR A 201 (-3.4A)None9CR A 201 (-3.6A) | 0.40A | 2aclC-1xiuA:30.9 | 2aclC-1xiuA:81.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xls | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275ASN A 306PHE A 313ARG A 316ALA A 327ILE A 345CYH A 432 | 9CR A 801 (-3.9A)9CR A 801 (-3.6A)9CR A 801 (-3.5A)9CR A 801 (-4.7A)None9CR A 801 (-4.3A)9CR A 801 (-2.6A)9CR A 801 (-3.3A)9CR A 801 ( 4.5A)9CR A 801 ( 3.7A) | 0.45A | 2aclC-1xlsA:29.8 | 2aclC-1xlsA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y0y | FRV OPERON PROTEINFRVX (Pyrococcushorikoshii) |
PF05343(Peptidase_M42) | 5 | ILE A 65ALA A 66ALA A 233ALA A 219ILE A 348 | None | 1.17A | 2aclC-1y0yA:undetectable | 2aclC-1y0yA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yt5 | INORGANICPOLYPHOSPHATE/ATP-NAD KINASE (Thermotogamaritima) |
PF01513(NAD_kinase) | 5 | ILE A 134ALA A 148ASN A 210ALA A 184ILE A 224 | None | 1.06A | 2aclC-1yt5A:undetectable | 2aclC-1yt5A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk7 | MERCURIC REDUCTASE (Pseudomonasaeruginosa) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 452ALA A 451GLN A 453ALA A 435ILE A 418 | NoneNoneGOL A3003 ( 3.8A)NoneNone | 0.95A | 2aclC-1zk7A:undetectable | 2aclC-1zk7A:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bku | IMPORTIN BETA-1SUBUNIT (Saccharomycescerevisiae) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | ILE B 119ALA B 116ALA B 115ASN B 99ALA B 154 | None | 1.11A | 2aclC-2bkuB:undetectable | 2aclC-2bkuB:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4m | GLYCOGENPHOSPHORYLASE (Corynebacteriumcallunae) |
PF00343(Phosphorylase) | 5 | ILE A 405ALA A 402ALA A 330ASN A 295ALA A 401 | None | 1.09A | 2aclC-2c4mA:undetectable | 2aclC-2c4mA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dg8 | PUTATIVE TETR-FAMILYTRANSCRIPTIONALREGULATORY PROTEIN (Streptomycescoelicolor) |
PF00440(TetR_N) | 5 | ILE A 35ALA A 17ALA A 39ARG A 63ALA A 16 | None | 1.15A | 2aclC-2dg8A:undetectable | 2aclC-2dg8A:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eo4 | 150AA LONGHYPOTHETICALHISTIDINE TRIADNUCLEOTIDE-BINDINGPROTEIN (Sulfurisphaeratokodaii) |
PF01230(HIT) | 5 | ILE A 39ALA A 23ALA A 24ARG A 9ILE A 92 | NoneNoneNoneNonePO4 A 202 ( 4.6A) | 1.16A | 2aclC-2eo4A:undetectable | 2aclC-2eo4A:23.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gl8 | RETINOIC ACIDRECEPTOR RXR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | PHE A 92ARG A 95ALA A 106ILE A 124CYH A 211 | None | 0.83A | 2aclC-2gl8A:27.9 | 2aclC-2gl8A:85.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnh | DNA POLYMERASE IIIALPHA SUBUNIT (Escherichiacoli) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 5 | ILE A 564ALA A 785ALA A 568PHE A 782ALA A 784 | None | 1.16A | 2aclC-2hnhA:undetectable | 2aclC-2hnhA:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2isj | BLUB (Sinorhizobiummeliloti) |
PF00881(Nitroreductase) | 5 | ILE A 168ALA A 91ARG A 104ALA A 92ILE A 111 | FMN A 502 (-4.5A)NoneNoneNoneNone | 1.12A | 2aclC-2isjA:undetectable | 2aclC-2isjA:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjf | L-LYSINE EPSILONAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00202(Aminotran_3) | 5 | ILE A 232ALA A 233ALA A 266ALA A 139ILE A 196 | None | 1.18A | 2aclC-2jjfA:undetectable | 2aclC-2jjfA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jss | CHIMERA OF HISTONEH2B.1 AND HISTONEH2A.Z (Saccharomycescerevisiae) |
PF00125(Histone)PF16211(Histone_H2A_C) | 5 | ILE A 62ALA A 45ALA A 42ALA A 49ILE A 131 | None | 1.17A | 2aclC-2jssA:undetectable | 2aclC-2jssA:25.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ksm | MYCOBACTERIUMTUBERCULOSISRV0899/MT0922/OMPATB (Mycobacteriumtuberculosis) |
PF04972(BON) | 5 | ALA A 104ALA A 105PHE A 97ALA A 101ILE A 84 | None | 1.17A | 2aclC-2ksmA:undetectable | 2aclC-2ksmA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0r | CALPAIN-9 (Homo sapiens) |
PF00648(Peptidase_C2) | 5 | ILE A 103ALA A 101ASN A 109ALA A 192ILE A 117 | None | 1.11A | 2aclC-2p0rA:undetectable | 2aclC-2p0rA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p88 | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Bacillus cereus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 175ALA A 177ASN A 213ALA A 146ILE A 217 | None | 1.13A | 2aclC-2p88A:undetectable | 2aclC-2p88A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2poz | PUTATIVE DEHYDRATASE (Mesorhizobiumjaponicum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 96ALA A 95ASN A 9ALA A 37ILE A 61 | None | 1.18A | 2aclC-2pozA:undetectable | 2aclC-2pozA:20.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q60 | RETINOID X RECEPTOR (Polyandrocarpamisakiensis) |
PF00104(Hormone_recep) | 6 | ASN A 181PHE A 188ARG A 191ALA A 202ILE A 220CYH A 307 | None | 0.70A | 2aclC-2q60A:28.0 | 2aclC-2q60A:71.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qm1 | GLUCOKINASE (Enterococcusfaecalis) |
PF00480(ROK) | 5 | ILE A 6ALA A 316GLN A 318ALA A 110ILE A 55 | None | 1.16A | 2aclC-2qm1A:undetectable | 2aclC-2qm1A:24.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhh | CG3027-PA (Drosophilamelanogaster) |
PF00795(CN_hydrolase) | 5 | ILE A 105ALA A 108ALA A 109ASN A 160ILE A 185 | None | 1.08A | 2aclC-2vhhA:undetectable | 2aclC-2vhhA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vre | DELTA(3,5)-DELTA(2,4)-DIENOYL-COAISOMERASE (Homo sapiens) |
PF00378(ECH_1) | 5 | ALA A 165ALA A 162GLN A 163ALA A 208ILE A 138 | None | 1.07A | 2aclC-2vreA:undetectable | 2aclC-2vreA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aoe | GLUTAMATEDEHYDROGENASE (Thermusthermophilus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ILE A 348ALA A 405ASN A 385ALA A 404ILE A 204 | None | 1.18A | 2aclC-3aoeA:undetectable | 2aclC-3aoeA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cty | THIOREDOXINREDUCTASE (Thermoplasmaacidophilum) |
PF07992(Pyr_redox_2) | 5 | ILE A 297ALA A 300PHE A 78ALA A 27ILE A 69 | FAD A1000 (-3.7A)FAD A1000 ( 4.0A)NoneFAD A1000 (-3.4A)None | 1.16A | 2aclC-3ctyA:undetectable | 2aclC-3ctyA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3do5 | HOMOSERINEDEHYDROGENASE (Archaeoglobusfulgidus) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 5 | ALA A 248GLN A 246PHE A 245ALA A 249ILE A 237 | None | 1.18A | 2aclC-3do5A:undetectable | 2aclC-3do5A:22.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 8 | ALA A 271ALA A 272GLN A 275ASN A 306PHE A 313ARG A 316ILE A 345CYH A 432 | 9CR A7223 (-3.5A)9CR A7223 (-4.2A)9CR A7223 (-4.6A)9CR A7223 (-3.9A)9CR A7223 (-4.5A)9CR A7223 (-3.7A)9CR A7223 ( 4.9A)9CR A7223 (-3.8A) | 0.77A | 2aclC-3dzuA:30.1 | 2aclC-3dzuA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 9 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327ILE A 345CYH A 432 | 9CR A7223 (-3.9A)9CR A7223 (-3.5A)9CR A7223 (-4.2A)9CR A7223 (-4.6A)9CR A7223 (-4.5A)9CR A7223 (-3.7A)9CR A7223 ( 4.7A)9CR A7223 ( 4.9A)9CR A7223 (-3.8A) | 0.81A | 2aclC-3dzuA:30.1 | 2aclC-3dzuA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e82 | PUTATIVEOXIDOREDUCTASE (Klebsiellapneumoniae) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | ALA A 340ALA A 341GLN A 351ASN A 209ILE A 235 | None | 1.07A | 2aclC-3e82A:undetectable | 2aclC-3e82A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fi8 | CHOLINE KINASE (Plasmodiumfalciparum) |
PF01633(Choline_kinase) | 5 | ILE A 323ALA A 319ALA A 385GLN A 384ALA A 316 | OPE A 442 ( 4.8A)NoneOPE A 442 ( 4.0A)NoneNone | 1.13A | 2aclC-3fi8A:undetectable | 2aclC-3fi8A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7k | 3-METHYLITACONATEISOMERASE (Eubacteriumbarkeri) |
PF04303(PrpF) | 5 | ALA A 172ALA A 202PHE A 261ALA A 173ILE A 99 | None | 1.18A | 2aclC-3g7kA:undetectable | 2aclC-3g7kA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7a | SHORT CHAINDEHYDROGENASE (Rhodopseudomonaspalustris) |
PF00106(adh_short) | 5 | ILE A 21ALA A 22ALA A 19ALA A 34ILE A 183 | ILE A 21 ( 0.6A)ALA A 22 ( 0.0A)ALA A 19 ( 0.0A)ALA A 34 ( 0.0A)ILE A 183 ( 0.7A) | 1.07A | 2aclC-3h7aA:undetectable | 2aclC-3h7aA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic6 | PUTATIVE METHYLASEFAMILY PROTEIN (Neisseriagonorrhoeae) |
PF00588(SpoU_methylase) | 5 | ILE A 28ALA A 31ALA A 32ASN A 89ILE A 92 | None | 1.05A | 2aclC-3ic6A:undetectable | 2aclC-3ic6A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3il3 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Haemophilusinfluenzae) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | ILE A 137ALA A 91GLN A 93ALA A 52ILE A 165 | None | 0.95A | 2aclC-3il3A:undetectable | 2aclC-3il3A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j0l | RIBOSOMAL PROTEINS14 (Oryctolaguscuniculus) |
PF00411(Ribosomal_S11) | 5 | ILE K 42ALA K 77ALA K 74GLN K 76ILE K 95 | None | 1.10A | 2aclC-3j0lK:undetectable | 2aclC-3j0lK:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m5w | TRYPTOPHANYL-TRNASYNTHETASE (Campylobacterjejuni) |
PF00579(tRNA-synt_1b) | 5 | ALA A 129ALA A 130PHE A 168ALA A 153ILE A 317 | None | 1.18A | 2aclC-3m5wA:undetectable | 2aclC-3m5wA:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvt | 3-DEOXY-D-ARABINO-HEPTULOSONATE7-PHOSPHATE SYNTHASE (Listeriamonocytogenes) |
PF00793(DAHP_synth_1)PF01817(CM_2) | 5 | ILE A 248ALA A 245ALA A 244ASN A 211ILE A 195 | None | 1.04A | 2aclC-3nvtA:undetectable | 2aclC-3nvtA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvt | 3-DEOXY-D-ARABINO-HEPTULOSONATE7-PHOSPHATE SYNTHASE (Listeriamonocytogenes) |
PF00793(DAHP_synth_1)PF01817(CM_2) | 5 | ILE A 248ALA A 245ALA A 244ASN A 214ILE A 195 | None | 1.13A | 2aclC-3nvtA:undetectable | 2aclC-3nvtA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pm9 | PUTATIVEOXIDOREDUCTASE (Rhodopseudomonaspalustris) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 5 | ALA A 332GLN A 329PHE A 234ALA A 324ILE A 340 | None | 1.05A | 2aclC-3pm9A:undetectable | 2aclC-3pm9A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfe | PUTATIVEDIHYDRODIPICOLINATESYNTHASE FAMILYPROTEIN (Coccidioidesimmitis) |
PF00701(DHDPS) | 5 | ALA A 270ALA A 265ASN A 51ALA A 278ILE A 47 | None | 1.15A | 2aclC-3qfeA:undetectable | 2aclC-3qfeA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgk | UREASE SUBUNIT BETA2 (Helicobactermustelae) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | ALA C 184ALA C 185ASN C 191PHE C 138ILE C 215 | None | 1.12A | 2aclC-3qgkC:undetectable | 2aclC-3qgkC:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr8 | BASEPLATE ASSEMBLYPROTEIN V (Escherichiavirus P2) |
PF04717(Phage_base_V) | 5 | ILE A 69ALA A 71ALA A 79ILE A 23CYH A 33 | None | 1.09A | 2aclC-3qr8A:undetectable | 2aclC-3qr8A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sll | PROBABLE ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 5 | ILE A 109ALA A 133GLN A 131ALA A 176ILE A 106 | None | 1.09A | 2aclC-3sllA:undetectable | 2aclC-3sllA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wc3 | ENDO-1,4-BETA-GLUCANASE (Eisenia fetida) |
PF00759(Glyco_hydro_9) | 5 | ALA A 178ALA A 177PHE A 87ALA A 86ILE A 332 | None | 1.04A | 2aclC-3wc3A:undetectable | 2aclC-3wc3A:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b7x | PROBABLEOXIDOREDUCTASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 5 | ILE A 178ALA A 179ALA A 157ILE A 217CYH A 213 | NoneNAP A 400 (-3.7A)NoneNoneNone | 1.06A | 2aclC-4b7xA:undetectable | 2aclC-4b7xA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dix | PLECTIN-RELATEDPROTEIN (Arabidopsisthaliana) |
PF16709(SCAB-IgPH) | 5 | ILE A 457ALA A 458ALA A 444GLN A 443ILE A 411 | None | 1.08A | 2aclC-4dixA:undetectable | 2aclC-4dixA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dut | NUCLEOSIDEDIPHOSPHATE KINASE (Burkholderiathailandensis) |
PF00334(NDK) | 6 | ILE A 23ALA A 115ALA A 14ASN A 18PHE A 107ALA A 108 | None | 1.39A | 2aclC-4dutA:undetectable | 2aclC-4dutA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f62 | GERANYLTRANSTRANSFERASE (Marinomonas sp.MED121) |
PF00348(polyprenyl_synt) | 5 | ALA A 211ALA A 267GLN A 270ALA A 207ILE A 46 | NoneNoneNoneNoneGOL A 402 (-4.3A) | 1.14A | 2aclC-4f62A:4.1 | 2aclC-4f62A:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0o | PROTEIN ARGONAUTE 5 (Arabidopsisthaliana) |
PF02171(Piwi) | 5 | ILE A 629ALA A 633ALA A 611ILE A 653CYH A 657 | None | 1.06A | 2aclC-4g0oA:undetectable | 2aclC-4g0oA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0y | PROTEIN ARGONAUTE 1 (Arabidopsisthaliana) |
PF02171(Piwi) | 5 | ILE A 610ALA A 650GLN A 654ILE A 704CYH A 698 | None | 1.10A | 2aclC-4g0yA:undetectable | 2aclC-4g0yA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifd | EXOSOME COMPLEXCOMPONENT RRP43 (Saccharomycescerevisiae) |
PF01138(RNase_PH) | 5 | ILE C 291ALA C 352PHE C 293ALA C 351ILE C 394 | None | 1.15A | 2aclC-4ifdC:undetectable | 2aclC-4ifdC:20.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 10 | ILE D 268ALA D 271ALA D 272GLN D 275ASN D 306PHE D 313ARG D 316ALA D 327ILE D 345CYH D 432 | None | 0.77A | 2aclC-4j5xD:28.5 | 2aclC-4j5xD:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jqo | ORNITHINECARBAMOYLTRANSFERASE (Vibriovulnificus) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | ALA A 67ALA A 68GLN A 71ASN A 48ILE A 105 | None | 1.05A | 2aclC-4jqoA:undetectable | 2aclC-4jqoA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn1 | TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 5 | ILE A 12ALA A 15ALA A 16GLN A 19ALA A 35 | None | 0.53A | 2aclC-4nn1A:undetectable | 2aclC-4nn1A:26.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pn3 | 3-HYDROXYACYL-COADEHYDROGENASE (Brucellamelitensis) |
PF00106(adh_short) | 5 | ILE A 80ALA A 73GLN A 56ALA A 72ILE A 143 | None | 1.11A | 2aclC-4pn3A:undetectable | 2aclC-4pn3A:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pq9 | BETA-1,3-GLUCANASE (Mycobacteriummarinum) |
PF00722(Glyco_hydro_16) | 5 | ILE A 90ALA A 101ALA A 92ARG A 55ILE A 120 | None | 1.14A | 2aclC-4pq9A:undetectable | 2aclC-4pq9A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pue | ENDO-1,4-BETA-XYLANASE (Geobacillusstearothermophilus) |
PF00331(Glyco_hydro_10) | 5 | ALA A 188ASN A 158PHE A 185ALA A 187ILE A 231 | NoneXYP A 403 (-3.2A)NoneNoneNone | 1.17A | 2aclC-4pueA:undetectable | 2aclC-4pueA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qji | PHOSPHOPANTOTHENOYLCYSTEINEDECARBOXYLASE/PHOSPHOPANTOTHENATE--CYSTEINE LIGASE (Mycolicibacteriumsmegmatis) |
PF04127(DFP) | 5 | ALA A 277ALA A 196PHE A 332ALA A 278ILE A 405 | CTP A 500 (-4.8A)NoneNoneNoneNone | 1.05A | 2aclC-4qjiA:undetectable | 2aclC-4qjiA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tv6 | 2-DEHYDRO-3-DEOXYGLUCARATE ALDOLASE (Staphylococcusaureus) |
PF03328(HpcH_HpaI) | 5 | ILE A 33ALA A 34ALA A 35ALA A 65ILE A 241 | None | 1.14A | 2aclC-4tv6A:undetectable | 2aclC-4tv6A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uie | SURFACE LAYERPROTEIN (Geobacillusstearothermophilus) |
no annotation | 5 | ILE A1069ALA A1025ALA A1026ALA A1032ILE A1093 | None | 1.16A | 2aclC-4uieA:undetectable | 2aclC-4uieA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b0v | MATRIX PROTEIN VP40 (Marburgmarburgvirus) |
PF07447(VP40) | 5 | ILE A 228ALA A 227PHE A 256ALA A 213ILE A 204 | None | 1.11A | 2aclC-5b0vA:undetectable | 2aclC-5b0vA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dle | PTS SYSTEM,FRUCTOSE-SPECIFICIIABC COMPONENT (Borreliellaburgdorferi) |
PF02302(PTS_IIB) | 5 | ALA A 182ALA A 183ASN A 209ALA A 225ILE A 205 | None | 1.07A | 2aclC-5dleA:undetectable | 2aclC-5dleA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 5 | ILE B 777ALA B 769GLN B 767ASN B 780ILE B 855 | None | 1.13A | 2aclC-5fq6B:undetectable | 2aclC-5fq6B:13.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hf4 | DISKS LARGE HOMOLOG4 (Rattusnorvegicus) |
PF00595(PDZ) | 6 | ALA A 375ALA A 378GLN A 374ASN A 363ALA A 370ILE A 314 | None | 1.47A | 2aclC-5hf4A:undetectable | 2aclC-5hf4A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iwx | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Bacillussubtilis) |
PF02542(YgbB) | 5 | ILE A 147ALA A 148ALA A 149GLN A 150ILE A 26 | None | 0.94A | 2aclC-5iwxA:undetectable | 2aclC-5iwxA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j6f | 3-DEOXY-D-ARABINO-HEPTULOSONATE7-PHOSPHATESYNTHASE, CHORISMATEMUTASE-ISOZYME 3 (Geobacillus sp.GHH01) |
PF00793(DAHP_synth_1)PF01817(CM_2) | 5 | ILE A 248ALA A 245ALA A 244ASN A 211ILE A 195 | None | 1.06A | 2aclC-5j6fA:undetectable | 2aclC-5j6fA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j6f | 3-DEOXY-D-ARABINO-HEPTULOSONATE7-PHOSPHATESYNTHASE, CHORISMATEMUTASE-ISOZYME 3 (Geobacillus sp.GHH01) |
PF00793(DAHP_synth_1)PF01817(CM_2) | 5 | ILE A 248ALA A 245ALA A 244ASN A 214ILE A 195 | None | 1.12A | 2aclC-5j6fA:undetectable | 2aclC-5j6fA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbw | 3-HYDROXYBUTYRYL-COADEHYDRATASE (Myxococcusxanthus) |
PF00378(ECH_1) | 5 | ILE A 102ALA A 101ALA A 100ALA A 190ILE A 166 | None | 1.02A | 2aclC-5jbwA:undetectable | 2aclC-5jbwA:26.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l39 | RMM MICROCOMPARTMENTSHELL PROTEINMSM0275 (Mycolicibacteriumsmegmatis) |
PF00936(BMC) | 5 | ALA A 188ALA A 191GLN A 187ALA A 160ILE A 10 | None | 1.18A | 2aclC-5l39A:undetectable | 2aclC-5l39A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l6m | RIBONUCLEASE VAPC (Caulobactervibrioides) |
PF01850(PIN) | 5 | ILE B 82ALA B 100ALA B 99GLN B 101ALA B 75 | None | 1.09A | 2aclC-5l6mB:undetectable | 2aclC-5l6mB:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5maw | FLAGELLAR PROTEINFLIS (Bacillussubtilis) |
no annotation | 5 | ILE E 35ALA E 39ALA E 38GLN E 40ILE E 60 | None | 1.08A | 2aclC-5mawE:undetectable | 2aclC-5mawE:25.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mnw | GUANYLATE CYCLASESOLUBLE SUBUNITBETA-1 (Homo sapiens) |
no annotation | 5 | ILE A 25ALA A 54ALA A 29ALA A 53ILE A 14 | None | 1.04A | 2aclC-5mnwA:undetectable | 2aclC-5mnwA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0g | PRECORRIN-8XMETHYLMUTASE (Rhodobactercapsulatus) |
no annotation | 5 | ILE A 196ALA A 44ALA A 43ASN A 202ILE A 160 | NoneNone8F5 A 301 ( 4.1A)8F5 A 301 (-3.8A)None | 1.07A | 2aclC-5n0gA:undetectable | 2aclC-5n0gA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ocm | NAD_GLY3P_DH,NAD-DEPENDENTGLYCEROL-3-PHOSPHATEDEHYDROGENASE (Streptosporangiumroseum) |
no annotation | 5 | ILE A 209ALA A 205ASN A 182ALA A 202ILE A 176 | None | 1.17A | 2aclC-5ocmA:undetectable | 2aclC-5ocmA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojl | IMINE REDUCTASE (Aspergillusterreus) |
no annotation | 6 | ILE A 137ALA A 135ALA A 125ALA A 132ILE A 68CYH A 70 | NoneNone9X5 A 301 ( 4.8A)NoneNoneNone | 1.26A | 2aclC-5ojlA:undetectable | 2aclC-5ojlA:13.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opt | 40S RIBOSOMALPROTEIN S21,PUTATIVE (Trypanosomacruzi) |
no annotation | 5 | ILE g 41ALA g 40GLN g 38PHE g 57ILE g 83 | None | 1.13A | 2aclC-5optg:undetectable | 2aclC-5optg:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDD (Methanothermobacterwolfeii) |
PF01568(Molydop_binding) | 6 | ILE D 78ALA D 30ALA D 31ASN D 50ALA D 29ILE D 107 | None | 1.47A | 2aclC-5t5iD:undetectable | 2aclC-5t5iD:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5txr | 5-AMINOLEVULINATESYNTHASE,MITOCHONDRIAL (Saccharomycescerevisiae) |
no annotation | 5 | ILE B 331ALA B 347ALA B 348ALA B 168ILE B 264 | None | 1.05A | 2aclC-5txrB:undetectable | 2aclC-5txrB:15.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 6 | ALA A 271ALA A 272PHE A 313ARG A 316ALA A 327ILE A 428 | 9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-3.4A)None | 1.38A | 2aclC-5uanA:29.8 | 2aclC-5uanA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 10 | ILE A 268ALA A 271ALA A 272GLN A 275ASN A 306PHE A 313ARG A 316ALA A 327ILE A 345CYH A 432 | 9CR A 503 (-4.0A)9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)None9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-3.4A)None9CR A 503 (-3.3A) | 0.62A | 2aclC-5uanA:29.8 | 2aclC-5uanA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5un0 | PROTEASOME ASSEMBLYCHAPERONE 2 (PAC2)HOMOLOGUE RV2125 (Mycobacteriumtuberculosis) |
PF09754(PAC2) | 5 | ILE 1 128ALA 1 185ALA 1 148ILE 1 170CYH 1 111 | None | 1.16A | 2aclC-5un01:undetectable | 2aclC-5un01:24.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wqw | N-ACETYLGLUCOSAMINIDASE (Clostridiumperfringens) |
PF01832(Glucosaminidase) | 5 | ALA A1060ALA A1059PHE A 951ALA A 954ILE A1107 | NoneEDO A1202 (-4.0A)NoneNoneNone | 1.14A | 2aclC-5wqwA:undetectable | 2aclC-5wqwA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cbo | C-6'AMINOTRANSFERASE (Micromonosporaechinospora) |
no annotation | 5 | ILE A 45ALA A 34PHE A 353ALA A 352ILE A 365 | None | 0.91A | 2aclC-6cboA:undetectable | 2aclC-6cboA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 5 | ILE A 129ALA A 132ALA A 133ALA A 266ILE A 180 | None | 0.90A | 2aclC-6d95A:undetectable | 2aclC-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6et9 | ACETYL-COAACETYLTRANSFERASETHIOLASE (Methanothermococcusthermolithotrophicus) |
no annotation | 5 | ILE A 26ALA A 29ALA A 215GLN A 11ILE A 63 | None | 1.10A | 2aclC-6et9A:undetectable | 2aclC-6et9A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f4f | GLUTATHIONETRANSFERASE (Trametesversicolor) |
no annotation | 5 | ILE A 88ALA A 28ALA A 30ALA A 95ILE A 78 | None | 1.18A | 2aclC-6f4fA:undetectable | 2aclC-6f4fA:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbu | F-BAR AND DOUBLE SH3DOMAINS PROTEIN 2 (Homo sapiens) |
no annotation | 5 | ILE A 28ALA A 8ALA A 26ASN A 47ILE A 50 | None | 1.15A | 2aclC-6gbuA:undetectable | 2aclC-6gbuA:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdg | TRXA,ADENOSINERECEPTOR A2A (Escherichiacoli;Homo sapiens) |
no annotation | 5 | ILE A 200ALA A 203ALA A 204GLN A 207ILE A 238 | None | 0.97A | 2aclC-6gdgA:undetectable | 2aclC-6gdgA:14.16 |