SIMILAR PATTERNS OF AMINO ACIDS FOR 2A3C_B_PNXB2434
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ghs | 1,3-BETA-GLUCANASE (Hordeum vulgare) |
PF00332(Glyco_hydro_17) | 4 | TYR A 22GLY A 233PHE A 274SER A 232 | None | 1.23A | 2a3cB-1ghsA:4.7 | 2a3cB-1ghsA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h54 | MALTOSEPHOSPHORYLASE (Lactobacillusbrevis) |
PF03632(Glyco_hydro_65m)PF03633(Glyco_hydro_65C)PF03636(Glyco_hydro_65N) | 4 | TYR A 698GLY A 736SER A 735ARG A 718 | None | 1.28A | 2a3cB-1h54A:undetectable | 2a3cB-1h54A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j2b | ARCHAEOSINETRNA-GUANINETRANSGLYCOSYLASE (Pyrococcushorikoshii) |
PF01472(PUA)PF01702(TGT)PF14809(TGT_C1)PF14810(TGT_C2) | 4 | TYR A 541GLY A 244PHE A 359ARG A 20 | None | 1.35A | 2a3cB-1j2bA:10.1 | 2a3cB-1j2bA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ns3 | NS3 PROTEASE (Hepacivirus C) |
PF02907(Peptidase_S29) | 4 | GLY A 137PHE A 43SER A 139ARG A 109 | None | 1.29A | 2a3cB-1ns3A:undetectable | 2a3cB-1ns3A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q20 | SULFOTRANSFERASEFAMILY, CYTOSOLIC,2B, MEMBER 1 ISOFORMB (Homo sapiens) |
PF00685(Sulfotransfer_1) | 4 | TYR A 34GLY A 109PHE A 111SER A 112 | None | 1.35A | 2a3cB-1q20A:undetectable | 2a3cB-1q20A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r20 | ECDYSONE RECEPTOR (Heliothisvirescens) |
PF00104(Hormone_recep) | 4 | TYR D 308GLY D 359PHE D 360SER D 361 | None | 1.09A | 2a3cB-1r20D:undetectable | 2a3cB-1r20D:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxj | ACTIVATOR 1 95 KDASUBUNIT (Saccharomycescerevisiae) |
PF00004(AAA)PF08519(RFC1) | 4 | TYR A 352GLY A 342PHE A 346SER A 343 | None | 1.16A | 2a3cB-1sxjA:undetectable | 2a3cB-1sxjA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v0f | ENDO-ALPHA-SIALIDASE (Enterobacteriaphage K1F) |
PF12217(End_beta_propel)PF12218(End_N_terminal)PF12219(End_tail_spike) | 4 | TYR A 716GLY A 597SER A 605ARG A 596 | TYR A 716 ( 1.3A)GLY A 597 ( 0.0A)SER A 605 ( 0.0A)ARG A 596 ( 0.6A) | 1.22A | 2a3cB-1v0fA:undetectable | 2a3cB-1v0fA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w63 | ADAPTER-RELATEDPROTEIN COMPLEX 1SIGMA 1A SUBUNIT (Mus musculus) |
PF01217(Clat_adaptor_s) | 4 | TYR Q 111GLY Q 12PHE Q 8SER Q 9 | None | 1.32A | 2a3cB-1w63Q:undetectable | 2a3cB-1w63Q:15.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6j | LANOSTEROL SYNTHASE (Homo sapiens) |
PF13243(SQHop_cyclase_C)PF13249(SQHop_cyclase_N) | 4 | TRP A 230TYR A 530PHE A 696SER A 699 | NoneNoneR71 A1733 (-3.6A)None | 1.39A | 2a3cB-1w6jA:undetectable | 2a3cB-1w6jA:21.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wno | CHITINASE (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 4 | TYR A 140GLY A 211SER A 214ARG A 263 | None | 0.36A | 2a3cB-1wnoA:69.9 | 2a3cB-1wnoA:99.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ye9 | CATALASE HPII (Escherichiacoli) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TRP E 512GLY E 526PHE E 527SER E 528 | None | 1.35A | 2a3cB-1ye9E:undetectable | 2a3cB-1ye9E:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z8l | GLUTAMATECARBOXYPEPTIDASE II (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 4 | TYR A 299GLY A 548PHE A 546SER A 547 | None | 1.19A | 2a3cB-1z8lA:2.1 | 2a3cB-1z8lA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zd1 | SULFOTRANSFERASE 4A1 (Homo sapiens) |
PF00685(Sulfotransfer_1) | 4 | TYR A 172GLY A 57PHE A 145SER A 141 | None | 1.39A | 2a3cB-1zd1A:undetectable | 2a3cB-1zd1A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aaa | ALPHA-AMYLASE (Aspergillusniger) |
PF00128(Alpha-amylase)PF09260(DUF1966) | 4 | TYR A 255GLY A 267PHE A 262SER A 264 | None | 1.36A | 2a3cB-2aaaA:9.3 | 2a3cB-2aaaA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmy | RIPENING-ASSOCIATEDPROTEIN (Musa acuminata) |
PF01419(Jacalin) | 4 | TRP A 10GLY A 75PHE A 94SER A 95 | None | 1.01A | 2a3cB-2bmyA:undetectable | 2a3cB-2bmyA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cjl | SECRETED CHITINASE (Streptomycescoelicolor) |
PF00182(Glyco_hydro_19) | 4 | TRP A 147TYR A 42GLY A 154SER A 176 | None | 1.11A | 2a3cB-2cjlA:undetectable | 2a3cB-2cjlA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cyg | BETA-1, 3-GLUCANANSE (Musa acuminata) |
PF00332(Glyco_hydro_17) | 4 | TYR A 50GLY A 266PHE A 309SER A 265 | None | 1.25A | 2a3cB-2cygA:11.1 | 2a3cB-2cygA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3j | EPOXIDE HYDROLASEEPHB (Mycobacteriumtuberculosis) |
PF00561(Abhydrolase_1) | 4 | TRP A 115GLY A 145PHE A 144SER A 142 | None | 1.37A | 2a3cB-2e3jA:undetectable | 2a3cB-2e3jA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2go4 | UDP-3-O-[3-HYDROXYMYRISTOYL]N-ACETYLGLUCOSAMINEDEACETYLASE (Aquifexaeolicus) |
PF03331(LpxC) | 4 | GLY A 263PHE A 261SER A 260ARG A 143 | None | 1.28A | 2a3cB-2go4A:undetectable | 2a3cB-2go4A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2im9 | HYPOTHETICAL PROTEIN (Legionellapneumophila) |
PF07313(DUF1460) | 4 | TYR A 92GLY A 98PHE A 108ARG A 156 | None | 1.33A | 2a3cB-2im9A:undetectable | 2a3cB-2im9A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2okx | RHAMNOSIDASE B (Bacillus sp.GL1) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 4 | TRP A 900PHE A 539SER A 538ARG A 540 | GOL A3006 (-4.3A)NoneNoneNone | 1.29A | 2a3cB-2okxA:undetectable | 2a3cB-2okxA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pan | GLYOXYLATECARBOLIGASE (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | TYR A 34GLY A 53PHE A 23SER A 55 | None | 1.17A | 2a3cB-2panA:undetectable | 2a3cB-2panA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pjq | UNCHARACTERIZEDPROTEIN LP_2664 (Lactobacillusplantarum) |
PF01966(HD) | 4 | TYR A 163GLY A 24SER A 23ARG A 135 | None | 1.31A | 2a3cB-2pjqA:undetectable | 2a3cB-2pjqA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pzi | PROBABLESERINE/THREONINE-PROTEIN KINASE PKNG (Mycobacteriumtuberculosis) |
PF00069(Pkinase)PF16918(PknG_TPR)PF16919(PknG_rubred) | 4 | TYR A 552GLY A 423PHE A 422ARG A 611 | None | 1.24A | 2a3cB-2pziA:undetectable | 2a3cB-2pziA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qf7 | PYRUVATE CARBOXYLASEPROTEIN (Rhizobium etli) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | TYR A 987GLY A 622SER A 666ARG A 621 | None | 1.27A | 2a3cB-2qf7A:7.5 | 2a3cB-2qf7A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qn0 | NEUROTOXIN (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | TYR A 322GLY A 41SER A 111ARG A 38 | None | 1.29A | 2a3cB-2qn0A:undetectable | 2a3cB-2qn0A:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uz0 | TRIBUTYRIN ESTERASE (Streptococcuspneumoniae) |
PF00756(Esterase) | 4 | TRP A 233GLY A 123PHE A 142SER A 141 | GOL A1259 ( 4.8A)NoneNoneNone | 1.36A | 2a3cB-2uz0A:undetectable | 2a3cB-2uz0A:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vg9 | BIFUNCTIONALENDO-1,4-BETA-XYLANASE A (Neocallimastixpatriciarum) |
PF00457(Glyco_hydro_11) | 4 | TYR A 96GLY A 62PHE A 61SER A 63 | None | 1.36A | 2a3cB-2vg9A:undetectable | 2a3cB-2vg9A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzs | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 4 | TRP A 527TYR A 579GLY A 641SER A 39 | None | 1.06A | 2a3cB-2wzsA:undetectable | 2a3cB-2wzsA:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0f | WSAF (Geobacillusstearothermophilus) |
no annotation | 4 | TYR A 308GLY A 63PHE A 62SER A 66 | TRH A 416 (-3.6A)TRH A 416 (-3.7A)NoneTRH A 416 (-3.6A) | 1.05A | 2a3cB-2x0fA:undetectable | 2a3cB-2x0fA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNITMEMBRANE-BOUNDHYDROGENASE SMALLSUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | TRP A 69TYR B 273GLY A 225SER B 254 | None | 1.39A | 2a3cB-3ayxA:undetectable | 2a3cB-3ayxA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNITMEMBRANE-BOUNDHYDROGENASE SMALLSUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases)PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | TRP A 69TYR B 273GLY A 226SER B 254 | None | 1.29A | 2a3cB-3ayxA:undetectable | 2a3cB-3ayxA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dra | GERANYLGERANYLTRANSFERASE TYPE I BETASUBUNIT (Candidaalbicans) |
PF00432(Prenyltrans) | 4 | TYR B 151PHE B 76SER B 96ARG B 77 | None | 1.28A | 2a3cB-3draB:undetectable | 2a3cB-3draB:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dtd | INVASION-ASSOCIATEDPROTEIN B (Bartonellahenselae) |
PF06776(IalB) | 4 | TRP A 50GLY A 92PHE A 135SER A 91 | None | 1.17A | 2a3cB-3dtdA:undetectable | 2a3cB-3dtdA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efe | THIJ/PFPI FAMILYPROTEIN (Bacillusanthracis) |
PF01965(DJ-1_PfpI) | 4 | TYR A 190GLY A 164PHE A 170SER A 163 | None | 1.36A | 2a3cB-3efeA:undetectable | 2a3cB-3efeA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f41 | PHYTASE (Mitsuokellamultacida) |
PF14566(PTPlike_phytase) | 4 | TYR A 512GLY A 400PHE A 546SER A 399 | None | 1.33A | 2a3cB-3f41A:undetectable | 2a3cB-3f41A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjn | THYMIDYLATE KINASE (Thermotogamaritima) |
PF02223(Thymidylate_kin) | 4 | TYR A 97GLY A 38SER A 67ARG A 47 | TYD A 401 (-3.8A)NoneNoneTYD A 401 (-2.9A) | 1.35A | 2a3cB-3hjnA:undetectable | 2a3cB-3hjnA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kao | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Staphylococcusaureus) |
PF01791(DeoC) | 4 | TYR A 129GLY A 251SER A 249ARG A 278 | NoneSO4 A 328 ( 4.5A)SO4 A 328 (-2.5A)None | 1.16A | 2a3cB-3kaoA:8.2 | 2a3cB-3kaoA:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ll8 | SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITALPHA ISOFORM (Homo sapiens) |
PF00149(Metallophos) | 4 | TYR A 291GLY A 89PHE A 306SER A 307 | None | 1.31A | 2a3cB-3ll8A:undetectable | 2a3cB-3ll8A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mde | MEDIUM CHAINACYL-COADEHYDROGENASE (Sus scrofa) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | TYR A 133GLY A 242PHE A 194SER A 182 | None | 1.37A | 2a3cB-3mdeA:undetectable | 2a3cB-3mdeA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3moz | MYO-INOSITOLHEXAPHOSPHATEPHOSPHOHYDROLASE (Selenomonasruminantium) |
PF14566(PTPlike_phytase) | 4 | TYR A 216GLY A 104PHE A 250SER A 103 | None | 1.31A | 2a3cB-3mozA:undetectable | 2a3cB-3mozA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oaj | PUTATIVERING-CLEAVINGDIOXYGENASE MHQO (Bacillussubtilis) |
PF00903(Glyoxalase) | 4 | TRP A 221GLY A 155PHE A 154SER A 84 | None | 1.27A | 2a3cB-3oajA:undetectable | 2a3cB-3oajA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3op0 | SIGNAL TRANSDUCTIONPROTEIN CBL-C (Homo sapiens) |
PF02262(Cbl_N)PF02761(Cbl_N2)PF02762(Cbl_N3) | 4 | TYR A 244GLY A 282SER A 279ARG A 255 | None | 1.40A | 2a3cB-3op0A:undetectable | 2a3cB-3op0A:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q5e | ATLASTIN-1 (Homo sapiens) |
PF02263(GBP) | 4 | TYR A 328GLY A 410PHE A 413SER A 414 | None | 1.06A | 2a3cB-3q5eA:undetectable | 2a3cB-3q5eA:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vns | NRPS ADENYLATIONPROTEIN CYTC1 (Streptomycessp.) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | TYR A 92GLY A 216PHE A 218SER A 219 | None | 0.83A | 2a3cB-3vnsA:undetectable | 2a3cB-3vnsA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wmy | EXTRACELLULAREXO-ALPHA-L-ARABINOFURANOSIDASE (Streptomycescoelicolor) |
PF03664(Glyco_hydro_62) | 4 | TRP A 197GLY A 242PHE A 229SER A 230 | None | 0.94A | 2a3cB-3wmyA:undetectable | 2a3cB-3wmyA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avr | PA4485 (Pseudomonasaeruginosa) |
PF03330(DPBB_1) | 4 | TYR A 9GLY A 39PHE A 38ARG A 56 | None | 1.31A | 2a3cB-4avrA:undetectable | 2a3cB-4avrA:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b9y | ALPHA-GLUCOSIDASE,PUTATIVE, ADG31B (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF17137(DUF5110) | 4 | TYR A 273GLY A 512PHE A 513ARG A 483 | None | 1.29A | 2a3cB-4b9yA:12.5 | 2a3cB-4b9yA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4db3 | N-ACETYL-D-GLUCOSAMINE KINASE (Vibriovulnificus) |
PF00480(ROK) | 4 | TYR A 262GLY A 133PHE A 134SER A 190 | None | 1.25A | 2a3cB-4db3A:undetectable | 2a3cB-4db3A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fch | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 4 | TRP A 192GLY A 249PHE A 253SER A 248 | None | 1.31A | 2a3cB-4fchA:undetectable | 2a3cB-4fchA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fem | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 4 | TRP A 192GLY A 249PHE A 253SER A 248 | ACX A 401 (-3.9A)NoneNoneNone | 1.34A | 2a3cB-4femA:undetectable | 2a3cB-4femA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fnm | E3 ALPHA-ESTERASE-7CARBOXYLESTERASE (Lucilia cuprina) |
PF00135(COesterase) | 4 | TYR A 444GLY A 352PHE A 421SER A 417 | None | 1.34A | 2a3cB-4fnmA:undetectable | 2a3cB-4fnmA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gdn | PROTEIN FLP (Staphylococcusaureus) |
PF00144(Beta-lactamase) | 4 | TRP A 315TYR A 311PHE A 336SER A 335 | None | 1.24A | 2a3cB-4gdnA:undetectable | 2a3cB-4gdnA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gzi | GLUCANENDO-1,3-BETA-D-GLUCOSIDASE (Solanumtuberosum) |
PF00332(Glyco_hydro_17) | 4 | TYR A 47GLY A 261PHE A 305SER A 260 | NoneNoneBGC A 401 (-3.8A)None | 1.24A | 2a3cB-4gziA:8.0 | 2a3cB-4gziA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ieg | RNA-DEPENDENT RNAPOLYMERASE P2 (Pseudomonasphage phi12) |
no annotation | 4 | TRP A 549GLY A 590PHE A 588SER A 587 | None | 1.20A | 2a3cB-4iegA:undetectable | 2a3cB-4iegA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iis | BETA-1,3-GLUCANASEFORM 'RRII GLN 2' (Heveabrasiliensis) |
PF00332(Glyco_hydro_17) | 4 | TYR A 23GLY A 242PHE A 284SER A 241 | None | 1.25A | 2a3cB-4iisA:7.9 | 2a3cB-4iisA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4il1 | CALMODULIN,CALCINEURIN SUBUNITB TYPE 1,SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITALPHA ISOFORM (Rattusnorvegicus) |
PF00149(Metallophos)PF13499(EF-hand_7) | 4 | TYR A 624GLY A 422PHE A 639SER A 640 | None | 1.37A | 2a3cB-4il1A:undetectable | 2a3cB-4il1A:20.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iu9 | NITRITE EXTRUSIONPROTEIN 2 (Escherichiacoli) |
no annotation | 4 | TRP B 50GLY B 266PHE B 268SER B 267 | None | 1.16A | 2a3cB-4iu9B:undetectable | 2a3cB-4iu9B:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jeu | SYNTAXIN-BINDINGPROTEIN 1 (Rattusnorvegicus) |
PF00995(Sec1) | 4 | TYR A 499GLY A 544SER A 569ARG A 235 | None | 1.10A | 2a3cB-4jeuA:2.4 | 2a3cB-4jeuA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jf7 | HEMAGGLUTININ-NEURAMINIDASE (Mammalianrubulavirus 5) |
no annotation | 4 | TYR D 176GLY D 551PHE D 553SER D 547 | None | 1.36A | 2a3cB-4jf7D:undetectable | 2a3cB-4jf7D:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l9a | PUTATIVEUNCHARACTERIZEDPROTEIN SMU.1393C (Streptococcusmutans) |
no annotation | 4 | TYR A 252PHE A 35SER A 63ARG A 200 | None | 1.22A | 2a3cB-4l9aA:undetectable | 2a3cB-4l9aA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ld7 | DIMETHYLALLYLTRYPTOPHAN SYNTHASE (Aspergillusfischeri) |
PF11991(Trp_DMAT) | 4 | TYR A 79GLY A 107PHE A 103SER A 104 | None | 0.81A | 2a3cB-4ld7A:undetectable | 2a3cB-4ld7A:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lix | ENT-COPALYLDIPHOSPHATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | TRP A 679GLY A 600PHE A 609SER A 605 | None | 1.26A | 2a3cB-4lixA:undetectable | 2a3cB-4lixA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lxl | LYSINE-SPECIFICDEMETHYLASE 4B (Homo sapiens) |
PF02373(JmjC)PF02375(JmjN) | 4 | TYR A 254GLY A 230PHE A 228SER A 232 | None | 1.28A | 2a3cB-4lxlA:undetectable | 2a3cB-4lxlA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4maa | PUTATIVEBRANCHED-CHAIN AMINOACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Pseudomonasprotegens) |
PF13458(Peripla_BP_6) | 4 | TYR A 362GLY A 231PHE A 230SER A 234 | NoneNoneGOL A 503 ( 4.8A)None | 1.16A | 2a3cB-4maaA:undetectable | 2a3cB-4maaA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbg | TERMINAL OXYGENASECOMPONENT OFCARBAZOLE (Janthinobacteriumsp. J3) |
PF00355(Rieske)PF11723(Aromatic_hydrox) | 4 | TRP A 285GLY A 131PHE A 34SER A 35 | None | 0.76A | 2a3cB-4nbgA:undetectable | 2a3cB-4nbgA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nx8 | PROTEIN-TYROSINEPHOSPHATASE 2 (Bdellovibriobacteriovorus) |
PF14566(PTPlike_phytase) | 4 | TYR A 170GLY A 72PHE A 204SER A 71 | None | 1.31A | 2a3cB-4nx8A:undetectable | 2a3cB-4nx8A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ora | SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITBETA ISOFORM (Homo sapiens) |
PF00149(Metallophos) | 4 | TYR A 300GLY A 98PHE A 315SER A 316 | None | 1.33A | 2a3cB-4oraA:undetectable | 2a3cB-4oraA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4orb | SERINE/THREONINE-PROTEIN PHOSPHATASE 2BCATALYTIC SUBUNITALPHA ISOFORM (Mus musculus) |
PF00149(Metallophos) | 4 | TYR A 291GLY A 89PHE A 306SER A 307 | None | 1.40A | 2a3cB-4orbA:undetectable | 2a3cB-4orbA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q38 | PUTATIVEUNCHARACTERIZEDPROTEIN TCP24 (Actinoplanesteichomyceticus) |
no annotation | 4 | TRP A 260GLY A 194PHE A 181SER A 182 | TEC A 404 (-4.0A)NoneNoneNone | 1.22A | 2a3cB-4q38A:undetectable | 2a3cB-4q38A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4raf | PROTEIN PHOSPHATASE1A (Homo sapiens) |
PF00481(PP2C)PF07830(PP2C_C) | 4 | TRP A 53TYR A 140GLY A 90SER A 88 | None | 1.29A | 2a3cB-4rafA:undetectable | 2a3cB-4rafA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uij | BTB/POZDOMAIN-CONTAININGADAPTER FORCUL3-MEDIATED RHOADEGRADATION PROTEIN1 (Homo sapiens) |
PF02214(BTB_2) | 4 | TYR A 123GLY A 72PHE A 70SER A 71 | None | 1.23A | 2a3cB-4uijA:undetectable | 2a3cB-4uijA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xqk | LLABIII (Lactococcuslactis) |
PF00271(Helicase_C)PF02384(N6_Mtase)PF04851(ResIII)PF13156(Mrr_cat_2) | 4 | TYR A1389GLY A1214PHE A1223SER A1221 | None | 0.93A | 2a3cB-4xqkA:undetectable | 2a3cB-4xqkA:14.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xw3 | ATP-DEPENDENT RNAHELICASE DDX1 (Homo sapiens) |
PF00622(SPRY) | 4 | TYR A 135GLY A 159PHE A 165SER A 174 | None | 0.84A | 2a3cB-4xw3A:undetectable | 2a3cB-4xw3A:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y7i | MYOTUBULARIN-RELATEDPROTEIN 8 (Homo sapiens) |
PF06602(Myotub-related) | 4 | GLY A 441PHE A 381SER A 382ARG A 447 | None | 1.37A | 2a3cB-4y7iA:undetectable | 2a3cB-4y7iA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a11 | THIOCYANATE FORMINGPROTEIN (Thlaspi arvense) |
PF01344(Kelch_1) | 4 | TRP A 234GLY A 188PHE A 189SER A 132 | NoneNoneNoneIOD A1350 ( 4.3A) | 1.40A | 2a3cB-5a11A:undetectable | 2a3cB-5a11A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b8i | SERINE/THREONINE-PROTEIN PHOSPHATASE (Coccidioidesimmitis) |
PF00149(Metallophos) | 4 | TYR A 309GLY A 107PHE A 324SER A 325 | None | 1.35A | 2a3cB-5b8iA:undetectable | 2a3cB-5b8iA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d3o | GLUTAMINASE KIDNEYISOFORM,MITOCHONDRIAL (Homo sapiens) |
PF04960(Glutaminase) | 4 | TYR A 535GLY A 469PHE A 477SER A 474 | None | 1.04A | 2a3cB-5d3oA:undetectable | 2a3cB-5d3oA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7s | GLYCOSIDE HYDROLASEFAMILY 31 (Trueperellapyogenes) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 4 | TYR A 479GLY A 518PHE A 519SER A 522 | None | 0.94A | 2a3cB-5f7sA:3.0 | 2a3cB-5f7sA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2v | IMPORTIN SUBUNITBETA-3 (Saccharomycescerevisiae) |
PF13513(HEAT_EZ) | 4 | TRP A 137GLY A 109PHE A 110SER A 112 | None | 1.23A | 2a3cB-5h2vA:undetectable | 2a3cB-5h2vA:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5b | THYMIDYLATE KINASE (Aquifexaeolicus) |
no annotation | 4 | TYR B 98GLY B 38SER B 67ARG B 47 | None | 1.33A | 2a3cB-5h5bB:undetectable | 2a3cB-5h5bB:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i61 | POTENTIALRNA-DEPENDENT RNAPOLYMERASE (Humanpicobirnavirus) |
no annotation | 4 | TRP B 8GLY B 143PHE B 147SER B 142 | None | 1.34A | 2a3cB-5i61B:undetectable | 2a3cB-5i61B:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j44 | SERINE PROTEASE SEPAAUTOTRANSPORTER (Shigellaflexneri) |
PF02395(Peptidase_S6) | 4 | TYR A 726GLY A 763PHE A 739SER A 762 | NoneEPE A1101 ( 4.7A)NoneNone | 1.38A | 2a3cB-5j44A:undetectable | 2a3cB-5j44A:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j5u | RAGB/SUSD DOMAINPROTEIN (Flavobacteriumjohnsoniae) |
PF12771(SusD-like_2) | 4 | TRP A 443TYR A 440GLY A 463SER A 459 | None | 1.38A | 2a3cB-5j5uA:undetectable | 2a3cB-5j5uA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jym | ANTIBODY SCFV TSP11 (Mus musculus) |
PF07686(V-set) | 4 | TYR B 236GLY B 173SER B 171ARG B 192 | None | 1.22A | 2a3cB-5jymB:undetectable | 2a3cB-5jymB:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l51 | (-)-MENTHONE:(+)-NEOMENTHOL REDUCTASE (Mentha xpiperita) |
PF00106(adh_short)PF13561(adh_short_C2) | 4 | TRP A 237GLY A 203PHE A 205SER A 206 | None | 1.10A | 2a3cB-5l51A:3.3 | 2a3cB-5l51A:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5neu | INTEGRIN ALPHA-V (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | TRP A 93GLY A 20PHE A 427SER A 407 | None | 1.40A | 2a3cB-5neuA:undetectable | 2a3cB-5neuA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swi | SUGAR HYDROLASE (Streptococcuspneumoniae) |
no annotation | 4 | TRP B 483TYR B 535GLY B 597SER B 21 | None | 1.10A | 2a3cB-5swiB:undetectable | 2a3cB-5swiB:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t4y | SUSC HOMOLOG (Bacteroidesthetaiotaomicron) |
no annotation | 4 | TYR D 771GLY D 946PHE D 948SER D 947 | None | 1.22A | 2a3cB-5t4yD:undetectable | 2a3cB-5t4yD:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uqe | GLUTAMINASE KIDNEYISOFORM,MITOCHONDRIAL (Homo sapiens) |
PF04960(Glutaminase)PF12796(Ank_2) | 4 | TYR A 530GLY A 464PHE A 472SER A 469 | None | 0.98A | 2a3cB-5uqeA:undetectable | 2a3cB-5uqeA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vem | ECTONUCLEOTIDEPYROPHOSPHATASE/PHOSPHODIESTERASE FAMILYMEMBER 5 (Homo sapiens) |
PF01663(Phosphodiest) | 4 | TYR A 157GLY A 37PHE A 35SER A 237 | None ZN A 501 ( 4.9A)NoneNone | 1.30A | 2a3cB-5vemA:undetectable | 2a3cB-5vemA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vip | MDCD (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans) | 4 | GLY B 219PHE B 216SER B 218ARG B 249 | None | 1.15A | 2a3cB-5vipB:undetectable | 2a3cB-5vipB:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wka | BETA-GLUCOSIDASE (metagenome) |
no annotation | 4 | TYR A 292GLY A 427PHE A 426SER A 429 | GOL A 501 (-4.3A)NoneNoneNone | 1.36A | 2a3cB-5wkaA:8.1 | 2a3cB-5wkaA:10.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3j | GLYCOSIDE HYDROLASEFAMILY 31 (Kribbellaflavida) |
no annotation | 4 | TYR A 463GLY A 502PHE A 503SER A 506 | None | 0.90A | 2a3cB-5x3jA:7.3 | 2a3cB-5x3jA:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgz | BETA-GLYCOSIDASE (unculturedmicroorganism) |
no annotation | 4 | TYR A 80GLY A 437PHE A 440SER A 441 | None | 1.33A | 2a3cB-5xgzA:5.4 | 2a3cB-5xgzA:9.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xra | CANNABINOID RECEPTOR1,FLAVODOXIN,CANNABINOID RECEPTOR 1 (Desulfovibriovulgaris;Homo sapiens) |
PF00001(7tm_1)PF00258(Flavodoxin_1) | 4 | TRP A 356GLY A 166PHE A 170SER A 167 | NoneNone8D3 A 602 ( 4.4A)None | 1.32A | 2a3cB-5xraA:undetectable | 2a3cB-5xraA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3o | SPIKE GLYCOPROTEIN (Murinecoronavirus) |
PF01601(Corona_S2) | 4 | TYR A1111GLY A 758PHE A1115SER A1116 | None | 0.81A | 2a3cB-6b3oA:undetectable | 2a3cB-6b3oA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PROTEIN FAM126A (Homo sapiens) |
no annotation | 4 | TYR C 109GLY C 235PHE C 236SER C 233 | None | 1.09A | 2a3cB-6bq1C:undetectable | 2a3cB-6bq1C:12.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0k | POLYSULPHIDEREDUCTASE NRFD (Rhodothermusmarinus) |
no annotation | 4 | TYR C 354GLY C 274PHE C 277SER C 278 | None | 1.37A | 2a3cB-6f0kC:undetectable | 2a3cB-6f0kC:12.83 |