SIMILAR PATTERNS OF AMINO ACIDS FOR 2A3C_B_PNXB2433_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1d2k | CHITINASE 1 (Coccidioidesimmitis) |
PF00704(Glyco_hydro_18) | 11 | TRP A 47PHE A 71GLY A 130THR A 132ASP A 169GLU A 171MET A 237TYR A 239ASP A 240TYR A 293TRP A 378 | None | 0.43A | 2a3cB-1d2kA:65.4 | 2a3cB-1d2kA:59.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6z | CHITINASE B (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 8 | PHE A 51GLY A 96ASP A 142GLU A 144MET A 212TYR A 214TYR A 292TRP A 403 | NGO A 502 (-4.7A)NGO A 502 ( 3.8A)NGO A 502 (-3.1A)NGO A 502 (-3.4A)NGO A 502 (-3.4A)NGO A 502 (-4.5A)NGO A 502 (-4.8A)NGO A 502 (-3.5A) | 0.89A | 2a3cB-1e6zA:12.5 | 2a3cB-1e6zA:28.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6z | CHITINASE B (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 7 | PHE A 51GLY A 96MET A 212TYR A 214ASP A 215TYR A 292TRP A 403 | NGO A 502 (-4.7A)NGO A 502 ( 3.8A)NGO A 502 (-3.4A)NGO A 502 (-4.5A)NGO A 502 ( 3.1A)NGO A 502 (-4.8A)NGO A 502 (-3.5A) | 0.42A | 2a3cB-1e6zA:12.5 | 2a3cB-1e6zA:28.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hjv | CHITINASE-3 LIKEPROTEIN 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 7 | TRP A 31PHE A 58GLY A 98MET A 204TYR A 206ASP A 207TRP A 352 | NAG A -2 (-4.2A)NAG A -2 (-4.7A)NAG A -2 ( 4.2A)NAG A 1 (-3.7A)NAG A -1 (-4.6A)NAG A -1 (-3.7A)NAG A -1 (-3.5A) | 0.61A | 2a3cB-1hjvA:43.3 | 2a3cB-1hjvA:30.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hkk | CHITOTRIOSIDASE-1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 7 | TRP A 31PHE A 58ASP A 138GLU A 140MET A 210TYR A 212TRP A 358 | NAA A1386 (-4.0A)AMI A1388 (-4.8A)AMI A1388 (-3.1A)AMI A1388 ( 3.3A)AMI A1388 (-3.3A)AMI A1388 (-4.8A)AMI A1388 (-3.5A) | 1.12A | 2a3cB-1hkkA:43.9 | 2a3cB-1hkkA:30.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hkk | CHITOTRIOSIDASE-1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 7 | TRP A 31PHE A 58ASP A 138MET A 210TYR A 212TYR A 267TRP A 358 | NAA A1386 (-4.0A)AMI A1388 (-4.8A)AMI A1388 (-3.1A)AMI A1388 (-3.3A)AMI A1388 (-4.8A)NAA A1387 (-3.6A)AMI A1388 (-3.5A) | 0.96A | 2a3cB-1hkkA:43.9 | 2a3cB-1hkkA:30.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hkk | CHITOTRIOSIDASE-1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 7 | TRP A 31PHE A 58GLY A 98GLU A 140MET A 210TYR A 212TRP A 358 | NAA A1386 (-4.0A)AMI A1388 (-4.8A)AMI A1388 ( 3.7A)AMI A1388 ( 3.3A)AMI A1388 (-3.3A)AMI A1388 (-4.8A)AMI A1388 (-3.5A) | 0.81A | 2a3cB-1hkkA:43.9 | 2a3cB-1hkkA:30.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hkk | CHITOTRIOSIDASE-1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | TRP A 31PHE A 58GLY A 98MET A 210TYR A 212ASP A 213TYR A 267TRP A 358 | NAA A1386 (-4.0A)AMI A1388 (-4.8A)AMI A1388 ( 3.7A)AMI A1388 (-3.3A)AMI A1388 (-4.8A)AMI A1388 ( 2.9A)NAA A1387 (-3.6A)AMI A1388 (-3.5A) | 0.51A | 2a3cB-1hkkA:43.9 | 2a3cB-1hkkA:30.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1itx | GLYCOSYL HYDROLASE (Bacilluscirculans) |
PF00704(Glyco_hydro_18) | 9 | TRP A 53PHE A 77GLY A 163THR A 165ASP A 202GLU A 204MET A 277TYR A 279TRP A 433 | NoneGOL A1007 (-4.8A)GOL A1007 ( 3.9A)NoneGOL A1007 (-3.6A)GOL A1007 (-3.7A)GOL A1007 ( 3.3A)GOL A1007 ( 4.8A)GOL A1007 (-4.8A) | 0.68A | 2a3cB-1itxA:15.7 | 2a3cB-1itxA:33.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1itx | GLYCOSYL HYDROLASE (Bacilluscirculans) |
PF00704(Glyco_hydro_18) | 10 | TRP A 53PHE A 77GLY A 163THR A 165ASP A 202MET A 277TYR A 279ASP A 280TYR A 338TRP A 433 | NoneGOL A1007 (-4.8A)GOL A1007 ( 3.9A)NoneGOL A1007 (-3.6A)GOL A1007 ( 3.3A)GOL A1007 ( 4.8A)NoneNoneGOL A1007 (-4.8A) | 0.41A | 2a3cB-1itxA:15.7 | 2a3cB-1itxA:33.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kfw | CHITINASE B (Arthrobactersp. TAD20) |
PF00704(Glyco_hydro_18) | 9 | TRP A 27PHE A 55GLY A 135THR A 137ASP A 190GLU A 192TYR A 271TYR A 328TRP A 412 | NoneNoneNoneNoneNoneGOL A 530 (-3.9A)GOL A 530 (-4.8A)NoneNone | 0.64A | 2a3cB-1kfwA:46.1 | 2a3cB-1kfwA:31.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kfw | CHITINASE B (Arthrobactersp. TAD20) |
PF00704(Glyco_hydro_18) | 9 | TRP A 27PHE A 55GLY A 135THR A 137ASP A 190TYR A 271ASP A 272TYR A 328TRP A 412 | NoneNoneNoneNoneNoneGOL A 530 (-4.8A)GOL A 530 (-3.7A)NoneNone | 0.47A | 2a3cB-1kfwA:46.1 | 2a3cB-1kfwA:31.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vf8 | SECRETORY PROTEIN (Mus musculus) |
PF00704(Glyco_hydro_18) | 7 | TRP A 10PHE A 37GLY A 77ASP A 117MET A 189TYR A 191TYR A 246 | None | 0.82A | 2a3cB-1vf8A:44.1 | 2a3cB-1vf8A:26.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vf8 | SECRETORY PROTEIN (Mus musculus) |
PF00704(Glyco_hydro_18) | 7 | TRP A 10PHE A 37GLY A 77MET A 189TYR A 191ASP A 192TYR A 246 | None | 0.47A | 2a3cB-1vf8A:44.1 | 2a3cB-1vf8A:26.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wb0 | CHITOTRIOSIDASE 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | TRP A 31PHE A 58GLY A 98ASP A 138GLU A 140MET A 210TYR A 212TRP A 360 | None | 1.02A | 2a3cB-1wb0A:43.6 | 2a3cB-1wb0A:30.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wb0 | CHITOTRIOSIDASE 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | TRP A 31PHE A 58GLY A 98ASP A 138MET A 210TYR A 212TYR A 267TRP A 360 | None | 0.83A | 2a3cB-1wb0A:43.6 | 2a3cB-1wb0A:30.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wb0 | CHITOTRIOSIDASE 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | TRP A 31PHE A 58GLY A 98MET A 210TYR A 212ASP A 213TYR A 267TRP A 360 | None | 0.43A | 2a3cB-1wb0A:43.6 | 2a3cB-1wb0A:30.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1wno | CHITINASE (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 11 | TRP A 14PHE A 38GLY A 98THR A 100ASP A 137GLU A 139MET A 205TYR A 207ASP A 208TYR A 261TRP A 346 | None | 0.64A | 2a3cB-1wnoA:69.9 | 2a3cB-1wnoA:99.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsj | PROTEIN PPL-2 (Parkiaplatycephala) |
PF00704(Glyco_hydro_18) | 6 | PHE A 32GLY A 80ASP A 125GLU A 127TYR A 182TRP A 253 | None | 1.11A | 2a3cB-2gsjA:19.7 | 2a3cB-2gsjA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uy3 | ENDOCHITINASE (Saccharomycescerevisiae) |
PF00704(Glyco_hydro_18) | 6 | PHE A 60GLY A 109ASP A 155GLU A 157TYR A 214TRP A 285 | H33 A1311 (-4.3A)H33 A1311 ( 3.8A)H33 A1311 (-3.0A)H33 A1311 (-3.7A)H33 A1311 (-4.7A)H33 A1311 (-3.5A) | 1.14A | 2a3cB-2uy3A:20.2 | 2a3cB-2uy3A:25.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 7 | TRP A 167PHE A 191ASP A 313GLU A 315MET A 388TYR A 390TRP A 539 | SN5 A1563 ( 4.0A)SN5 A1564 (-4.6A)NGT A1565 (-3.4A)SN5 A1566 ( 2.9A)NGT A1565 (-3.7A)NGT A1565 (-4.7A)NGT A1565 ( 3.5A) | 1.01A | 2a3cB-2wk2A:43.5 | 2a3cB-2wk2A:28.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 7 | TRP A 167PHE A 191ASP A 313MET A 388TYR A 390TYR A 444TRP A 539 | SN5 A1563 ( 4.0A)SN5 A1564 (-4.6A)NGT A1565 (-3.4A)NGT A1565 (-3.7A)NGT A1565 (-4.7A)NGT A1565 ( 4.9A)NGT A1565 ( 3.5A) | 0.83A | 2a3cB-2wk2A:43.5 | 2a3cB-2wk2A:28.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 8 | TRP A 167PHE A 191GLY A 274THR A 276GLU A 315MET A 388TYR A 390TRP A 539 | SN5 A1563 ( 4.0A)SN5 A1564 (-4.6A)NGT A1565 ( 3.9A)SN5 A1563 ( 3.3A)SN5 A1566 ( 2.9A)NGT A1565 (-3.7A)NGT A1565 (-4.7A)NGT A1565 ( 3.5A) | 0.72A | 2a3cB-2wk2A:43.5 | 2a3cB-2wk2A:28.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 9 | TRP A 167PHE A 191GLY A 274THR A 276MET A 388TYR A 390ASP A 391TYR A 444TRP A 539 | SN5 A1563 ( 4.0A)SN5 A1564 (-4.6A)NGT A1565 ( 3.9A)SN5 A1563 ( 3.3A)NGT A1565 (-3.7A)NGT A1565 (-4.7A)NGT A1565 (-2.9A)NGT A1565 ( 4.9A)NGT A1565 ( 3.5A) | 0.40A | 2a3cB-2wk2A:43.5 | 2a3cB-2wk2A:28.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvn | ASPERGILLUSFUMIGATUS CHITINASEA1 (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 6 | PHE A 60GLY A 123ASP A 172GLU A 174TYR A 232TRP A 312 | NoneNoneKLS A1338 (-2.8A)KLS A1338 (-2.9A)KLS A1338 (-4.8A)KLS A1338 (-3.5A) | 1.16A | 2a3cB-2xvnA:21.1 | 2a3cB-2xvnA:23.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ybu | ACIDIC MAMMALIANCHITINASE (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | TRP A 31PHE A 58GLY A 98ASP A 138GLU A 140MET A 210TYR A 212TRP A 360 | CX9 A1398 ( 3.4A)CX9 A1398 (-4.5A)CX9 A1398 (-3.5A)CX9 A1398 (-3.0A)CX9 A1398 (-3.7A)CX9 A1398 (-3.3A)CX9 A1398 (-4.3A)CX9 A1398 ( 3.3A) | 1.03A | 2a3cB-2ybuA:44.6 | 2a3cB-2ybuA:31.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ybu | ACIDIC MAMMALIANCHITINASE (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | TRP A 31PHE A 58GLY A 98ASP A 138MET A 210TYR A 212TYR A 267TRP A 360 | CX9 A1398 ( 3.4A)CX9 A1398 (-4.5A)CX9 A1398 (-3.5A)CX9 A1398 (-3.0A)CX9 A1398 (-3.3A)CX9 A1398 (-4.3A)NoneCX9 A1398 ( 3.3A) | 0.84A | 2a3cB-2ybuA:44.6 | 2a3cB-2ybuA:31.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ybu | ACIDIC MAMMALIANCHITINASE (Homo sapiens) |
PF00704(Glyco_hydro_18) | 8 | TRP A 31PHE A 58GLY A 98MET A 210TYR A 212ASP A 213TYR A 267TRP A 360 | CX9 A1398 ( 3.4A)CX9 A1398 (-4.5A)CX9 A1398 (-3.5A)CX9 A1398 (-3.3A)CX9 A1398 (-4.3A)CX9 A1398 ( 4.4A)NoneCX9 A1398 ( 3.3A) | 0.43A | 2a3cB-2ybuA:44.6 | 2a3cB-2ybuA:31.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3alf | CHITINASE, CLASS V (Nicotianatabacum) |
PF00704(Glyco_hydro_18) | 8 | PHE A 31GLY A 73ASP A 113GLU A 115MET A 181TYR A 183ASP A 184TRP A 326 | EDO A 357 (-4.8A)EDO A 357 ( 4.2A)EDO A 357 (-4.2A)EDO A 357 (-2.8A)EDO A 357 ( 3.3A)EDO A 359 ( 4.7A)EDO A 359 (-4.5A)EDO A 357 (-4.4A) | 0.59A | 2a3cB-3alfA:41.6 | 2a3cB-3alfA:29.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3alf | CHITINASE, CLASS V (Nicotianatabacum) |
PF00704(Glyco_hydro_18) | 8 | PHE A 31GLY A 73ASP A 113MET A 181TYR A 183ASP A 184TYR A 234TRP A 326 | EDO A 357 (-4.8A)EDO A 357 ( 4.2A)EDO A 357 (-4.2A)EDO A 357 ( 3.3A)EDO A 359 ( 4.7A)EDO A 359 (-4.5A)NoneEDO A 357 (-4.4A) | 0.37A | 2a3cB-3alfA:41.6 | 2a3cB-3alfA:29.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqu | AT4G19810 (Arabidopsisthaliana) |
PF00704(Glyco_hydro_18) | 8 | PHE A 32GLY A 74ASP A 114GLU A 116MET A 182TYR A 184ASP A 185TRP A 324 | None | 0.62A | 2a3cB-3aquA:41.5 | 2a3cB-3aquA:27.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqu | AT4G19810 (Arabidopsisthaliana) |
PF00704(Glyco_hydro_18) | 8 | PHE A 32GLY A 74ASP A 114MET A 182TYR A 184ASP A 185TYR A 235TRP A 324 | None | 0.38A | 2a3cB-3aquA:41.5 | 2a3cB-3aquA:27.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9e | CHITINASE A (Vibrio harveyi) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 10 | TRP A 168PHE A 192GLY A 274THR A 276ASP A 313MET A 389TYR A 391ASP A 392TYR A 461TRP A 570 | None | 0.59A | 2a3cB-3b9eA:39.9 | 2a3cB-3b9eA:27.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebv | CHINITASE A (Streptomycescoelicolor) |
PF00704(Glyco_hydro_18) | 6 | PHE A 37GLY A 84ASP A 119GLU A 121TYR A 181TRP A 271 | None | 1.08A | 2a3cB-3ebvA:22.9 | 2a3cB-3ebvA:25.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnd | CHITINASE (Bacteroidesthetaiotaomicron) |
PF00704(Glyco_hydro_18) | 6 | PHE A 79ASP A 155GLU A 157MET A 211TYR A 213TRP A 322 | None | 1.15A | 2a3cB-3fndA:31.6 | 2a3cB-3fndA:24.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnd | CHITINASE (Bacteroidesthetaiotaomicron) |
PF00704(Glyco_hydro_18) | 6 | PHE A 79ASP A 155MET A 211TYR A 213TYR A 256TRP A 322 | NoneNoneNoneNoneGOL A 356 (-4.3A)None | 0.99A | 2a3cB-3fndA:31.6 | 2a3cB-3fndA:24.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnd | CHITINASE (Bacteroidesthetaiotaomicron) |
PF00704(Glyco_hydro_18) | 6 | PHE A 79MET A 211TYR A 213ASP A 214TYR A 256TRP A 322 | NoneNoneNoneNoneGOL A 356 (-4.3A)None | 0.38A | 2a3cB-3fndA:31.6 | 2a3cB-3fndA:24.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g6l | CHITINASE (Clonostachysrosea) |
PF00704(Glyco_hydro_18) | 11 | TRP A 50PHE A 74GLY A 133THR A 135ASP A 172GLU A 174MET A 240TYR A 242ASP A 243TYR A 296TRP A 381 | None | 0.69A | 2a3cB-3g6lA:63.7 | 2a3cB-3g6lA:54.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ian | CHITINASE (Lactococcuslactis) |
PF00704(Glyco_hydro_18) | 6 | TRP A 52PHE A 84GLY A 126ASP A 160TYR A 229TRP A 321 | NoneNoneEDO A 369 ( 3.7A)EDO A 361 ( 2.7A)EDO A 361 (-4.5A)EDO A 361 (-4.5A) | 0.99A | 2a3cB-3ianA:21.8 | 2a3cB-3ianA:24.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qok | PUTATIVE CHITINASEII (Klebsiellapneumoniae) |
PF00704(Glyco_hydro_18) | 7 | PHE A 58GLY A 113ASP A 151GLU A 153MET A 220TYR A 222TRP A 395 | None | 0.71A | 2a3cB-3qokA:37.7 | 2a3cB-3qokA:29.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qok | PUTATIVE CHITINASEII (Klebsiellapneumoniae) |
PF00704(Glyco_hydro_18) | 8 | PHE A 58GLY A 113ASP A 151MET A 220TYR A 222ASP A 223TYR A 276TRP A 395 | None | 0.41A | 2a3cB-3qokA:37.7 | 2a3cB-3qokA:29.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w4r | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18) | 9 | TRP A 34PHE A 61GLY A 106ASP A 146GLU A 148MET A 215TYR A 217ASP A 218TRP A 372 | None | 0.72A | 2a3cB-3w4rA:10.8 | 2a3cB-3w4rA:25.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w4r | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18) | 9 | TRP A 34PHE A 61GLY A 106ASP A 146MET A 215TYR A 217ASP A 218TYR A 272TRP A 372 | None | 0.50A | 2a3cB-3w4rA:10.8 | 2a3cB-3w4rA:25.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wl1 | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18) | 8 | TRP A 34PHE A 61GLY A 106ASP A 146GLU A 148MET A 215TYR A 217TRP A 372 | NAG A 503 ( 4.0A)NAG A 501 (-4.5A)NAG A 501 (-3.6A)NAG A 501 (-3.0A)NAG A 501 (-2.7A)NAG A 501 (-3.5A)NAG A 501 (-4.6A)NAG A 501 (-3.7A) | 1.01A | 2a3cB-3wl1A:8.9 | 2a3cB-3wl1A:27.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wl1 | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18) | 9 | TRP A 34PHE A 61GLY A 106ASP A 146MET A 215TYR A 217ASP A 218TYR A 272TRP A 372 | NAG A 503 ( 4.0A)NAG A 501 (-4.5A)NAG A 501 (-3.6A)NAG A 501 (-3.0A)NAG A 501 (-3.5A)NAG A 501 (-4.6A)NAG A 501 ( 3.2A)NAG A 502 (-3.9A)NAG A 501 (-3.7A) | 0.85A | 2a3cB-3wl1A:8.9 | 2a3cB-3wl1A:27.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 7 | PHE A 117GLY A 214ASP A 254GLU A 256ASP A 326TYR A 379TRP A 486 | None | 0.99A | 2a3cB-4a5qA:34.5 | 2a3cB-4a5qA:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 7 | TRP A 77PHE A 117ASP A 254MET A 323TYR A 325ASP A 326TYR A 379 | None | 1.01A | 2a3cB-4a5qA:34.5 | 2a3cB-4a5qA:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 8 | TRP A 77PHE A 117GLY A 214ASP A 254GLU A 256MET A 323ASP A 326TYR A 379 | None | 0.86A | 2a3cB-4a5qA:34.5 | 2a3cB-4a5qA:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axn | CHITINASE C1 (Serratiamarcescens) |
PF00704(Glyco_hydro_18) | 6 | TRP A 34PHE A 66GLY A 105ASP A 139TYR A 208TRP A 300 | NoneNoneNoneACT A1331 (-2.7A)ACT A1331 (-4.6A)ACT A1330 ( 4.1A) | 1.07A | 2a3cB-4axnA:20.3 | 2a3cB-4axnA:26.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ay1 | CHITINASE-3-LIKEPROTEIN 2 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 6 | TRP A 36PHE A 63GLY A 103ASP A 213TYR A 269TRP A 360 | NAG A 400 (-4.3A)NoneNAG A 401 (-3.5A)NAG A 401 (-2.8A)NAG A 400 (-3.7A)NAG A 401 (-3.7A) | 0.60A | 2a3cB-4ay1A:43.0 | 2a3cB-4ay1A:28.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 6 | PHE A 200GLY A 307ASP A 347ASP A 425TYR A 482TRP A 582 | NoneNoneNoneNoneNoneGOL A 701 (-4.2A) | 0.86A | 2a3cB-4dwsA:34.0 | 2a3cB-4dwsA:26.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 6 | TRP A 160PHE A 200GLY A 307ASP A 347GLU A 349MET A 422 | GOL A 701 (-3.9A)NoneNoneNoneNoneNone | 0.80A | 2a3cB-4dwsA:34.0 | 2a3cB-4dwsA:26.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dws | CHI2 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 8 | TRP A 160PHE A 200GLY A 307ASP A 347MET A 422TYR A 424ASP A 425TYR A 482 | GOL A 701 (-3.9A)NoneNoneNoneNoneNoneNoneNone | 0.53A | 2a3cB-4dwsA:34.0 | 2a3cB-4dwsA:26.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mb5 | CHITINASE 60 (Moritellamarina) |
PF00704(Glyco_hydro_18)PF16403(DUF5011) | 6 | TRP A 40PHE A 70GLY A 117ASP A 151TYR A 220TRP A 311 | PEG A 614 (-3.7A)NAG A 608 (-4.4A)NAG A 608 ( 3.9A)NAG A 608 (-3.4A)NAG A 609 (-4.4A)NAG A 608 (-3.5A) | 0.96A | 2a3cB-4mb5A:21.0 | 2a3cB-4mb5A:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnm | CHITINASE A (Cycas revoluta) |
PF00704(Glyco_hydro_18) | 7 | PHE A 34GLY A 76ASP A 117MET A 189TYR A 191ASP A 192TRP A 327 | None | 0.88A | 2a3cB-4mnmA:41.0 | 2a3cB-4mnmA:28.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 6 | PHE A 58ASP A 151GLU A 153MET A 220TYR A 222TRP A 395 | NoneACT A 502 (-3.0A)ACT A 502 (-3.8A)ACT A 502 ( 3.1A)GOL A 504 ( 4.6A)GOL A 504 (-3.7A) | 1.04A | 2a3cB-4q22A:37.7 | 2a3cB-4q22A:30.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 6 | PHE A 58GLY A 113GLU A 153MET A 220TYR A 222TRP A 395 | NoneACT A 502 ( 4.6A)ACT A 502 (-3.8A)ACT A 502 ( 3.1A)GOL A 504 ( 4.6A)GOL A 504 (-3.7A) | 0.73A | 2a3cB-4q22A:37.7 | 2a3cB-4q22A:30.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 7 | PHE A 58GLY A 113MET A 220TYR A 222ASP A 223TYR A 276TRP A 395 | NoneACT A 502 ( 4.6A)ACT A 502 ( 3.1A)GOL A 504 ( 4.6A)GOL A 504 (-2.7A)GOL A 504 ( 4.7A)GOL A 504 (-3.7A) | 0.37A | 2a3cB-4q22A:37.7 | 2a3cB-4q22A:30.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6t | GLYCOSYL HYDROLASE,FAMILY 18 (Pseudomonasprotegens) |
PF00704(Glyco_hydro_18) | 6 | ASP A 147MET A 211TYR A 213ASP A 214TYR A 263TRP A 349 | None | 0.97A | 2a3cB-4q6tA:30.8 | 2a3cB-4q6tA:24.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 6 | ASP A 217GLU A 219MET A 281TYR A 283TYR A 324TRP A 407 | None | 1.06A | 2a3cB-4s3jA:30.0 | 2a3cB-4s3jA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 6 | ASP A 217MET A 281TYR A 283ASP A 284TYR A 324TRP A 407 | None | 0.84A | 2a3cB-4s3jA:30.0 | 2a3cB-4s3jA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 6 | PHE A 138ASP A 217GLU A 219MET A 281TYR A 283TYR A 324 | None | 1.29A | 2a3cB-4s3jA:30.0 | 2a3cB-4s3jA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 6 | PHE A 138ASP A 217MET A 281TYR A 283ASP A 284TYR A 324 | None | 1.13A | 2a3cB-4s3jA:30.0 | 2a3cB-4s3jA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txg | CHITINASE (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18)PF06483(ChiC) | 9 | TRP A 163PHE A 190GLY A 254ASP A 312GLU A 314MET A 395TYR A 397ASP A 398TRP A 603 | NoneNoneNoneNone CS A 803 (-2.9A) CS A 803 (-3.5A) CS A 812 (-4.4A) CS A 812 (-4.0A) CS A 812 ( 4.2A) | 0.91A | 2a3cB-4txgA:34.8 | 2a3cB-4txgA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txg | CHITINASE (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18)PF06483(ChiC) | 9 | TRP A 163PHE A 190GLY A 254ASP A 312MET A 395TYR A 397ASP A 398TYR A 464TRP A 603 | NoneNoneNoneNone CS A 803 (-3.5A) CS A 812 (-4.4A) CS A 812 (-4.0A) CS A 812 (-4.5A) CS A 812 ( 4.2A) | 0.77A | 2a3cB-4txgA:34.8 | 2a3cB-4txgA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uri | CHITINASE-RELATEDAGGLUTININ (Robiniapseudoacacia) |
PF00704(Glyco_hydro_18) | 8 | PHE A 30GLY A 72ASP A 114GLU A 116MET A 183TYR A 185ASP A 186TRP A 317 | NoneMPD A 401 ( 4.6A)MPD A 401 (-4.3A)MPD A 401 (-2.7A)MPD A 401 (-3.0A)MPD A 401 (-4.8A)NoneMPD A 401 (-3.8A) | 0.78A | 2a3cB-4uriA:40.6 | 2a3cB-4uriA:26.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uri | CHITINASE-RELATEDAGGLUTININ (Robiniapseudoacacia) |
PF00704(Glyco_hydro_18) | 8 | PHE A 30GLY A 72ASP A 114MET A 183TYR A 185ASP A 186TYR A 236TRP A 317 | NoneMPD A 401 ( 4.6A)MPD A 401 (-4.3A)MPD A 401 (-3.0A)MPD A 401 (-4.8A)NoneNoneMPD A 401 (-3.8A) | 0.57A | 2a3cB-4uriA:40.6 | 2a3cB-4uriA:26.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w5u | CHITINASE (Streptomycesthermoviolaceus) |
no annotation | 9 | PHE B 78GLY B 141THR B 143ASP B 181GLU B 183TYR B 250ASP B 251TYR B 305TRP B 388 | NoneNoneNoneNoneNoneNoneMLI B 501 ( 4.7A)NoneNone | 0.96A | 2a3cB-4w5uB:44.5 | 2a3cB-4w5uB:32.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w5u | CHITINASE (Streptomycesthermoviolaceus) |
no annotation | 10 | TRP B 50PHE B 78GLY B 141THR B 143ASP B 181GLU B 183MET B 248TYR B 250ASP B 251TYR B 305 | NoneNoneNoneNoneNoneNoneNoneNoneMLI B 501 ( 4.7A)None | 0.78A | 2a3cB-4w5uB:44.5 | 2a3cB-4w5uB:32.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5z | CHITINASE 60 (Moritellamarina) |
PF00704(Glyco_hydro_18) | 6 | TRP A 40PHE A 70GLY A 117ASP A 151TYR A 220TRP A 311 | CL A 408 (-4.3A)NoneNoneACT A 404 (-2.7A)ACT A 404 (-4.6A)MPD A 402 ( 3.4A) | 0.94A | 2a3cB-4w5zA:20.4 | 2a3cB-4w5zA:26.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wiw | GLYCOSIDE HYDROLASEFAMILY 18 (Desulfitobacteriumhafniense) |
PF00704(Glyco_hydro_18) | 5 | MET A 530TYR A 532ASP A 533TYR A 574TRP A 666 | CA A 704 ( 4.4A)NoneNoneNoneNone | 0.42A | 2a3cB-4wiwA:29.5 | 2a3cB-4wiwA:25.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5df0 | AC-CHIA (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 11 | TRP A 157PHE A 181GLY A 264THR A 266ASP A 303GLU A 305MET A 379TYR A 381ASP A 382TYR A 435TRP A 528 | None58Y A 605 (-4.5A)58Y A 605 ( 4.2A)SN5 A 604 (-3.1A)None58Y A 605 (-3.1A)58Y A 605 (-3.3A)58Y A 605 (-4.9A)58Y A 605 ( 3.0A)None58Y A 605 (-3.7A) | 0.65A | 2a3cB-5df0A:43.4 | 2a3cB-5df0A:27.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpr | CHITINASE (Ostriniafurnacalis) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 11 | TRP A 160PHE A 184GLY A 267THR A 269ASP A 306GLU A 308MET A 381TYR A 383ASP A 384TYR A 437TRP A 532 | TRP A 160 ( 0.5A)PHE A 184 ( 1.3A)GLY A 267 ( 0.0A)THR A 269 ( 0.8A)ASP A 306 ( 0.5A)GLU A 308 ( 0.6A)MET A 381 ( 0.0A)TYR A 383 ( 1.3A)ASP A 384 ( 0.5A)TYR A 437 ( 1.3A)TRP A 532 ( 0.5A) | 0.71A | 2a3cB-5gprA:43.1 | 2a3cB-5gprA:27.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP B 568PHE B 590GLY B 651ASP B 689GLU B 691MET B 764TYR B 766ASP B 767TRP B 905 | None | 0.70A | 2a3cB-5gztB:41.2 | 2a3cB-5gztB:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP B 568PHE B 590GLY B 651ASP B 689MET B 764TYR B 766ASP B 767TYR B 816TRP B 905 | None | 0.46A | 2a3cB-5gztB:41.2 | 2a3cB-5gztB:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP B1055PHE B1077GLY B1137ASP B1175GLU B1177MET B1250TYR B1252ASP B1253TRP B1396 | None | 0.73A | 2a3cB-5gztB:41.2 | 2a3cB-5gztB:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzt | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP B1055PHE B1077GLY B1137ASP B1175MET B1250TYR B1252ASP B1253TYR B1304TRP B1396 | None | 0.53A | 2a3cB-5gztB:41.2 | 2a3cB-5gztB:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP A 568PHE A 590GLY A 651ASP A 689GLU A 691MET A 764TYR A 766ASP A 767TRP A 905 | None | 0.69A | 2a3cB-5gzuA:41.2 | 2a3cB-5gzuA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP A 568PHE A 590GLY A 651ASP A 689MET A 764TYR A 766ASP A 767TYR A 816TRP A 905 | None | 0.51A | 2a3cB-5gzuA:41.2 | 2a3cB-5gzuA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP A1055PHE A1077GLY A1137ASP A1175GLU A1177MET A1250TYR A1252ASP A1253TRP A1396 | None | 0.73A | 2a3cB-5gzuA:41.2 | 2a3cB-5gzuA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 9 | TRP A1055PHE A1077GLY A1137ASP A1175MET A1250TYR A1252ASP A1253TYR A1304TRP A1396 | None | 0.58A | 2a3cB-5gzuA:41.2 | 2a3cB-5gzuA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvb | CHITINASE (Ostriniafurnacalis) |
no annotation | 9 | TRP A 102PHE A 129GLY A 175ASP A 215MET A 283TYR A 285ASP A 286TYR A 340TRP A 433 | NAG A 506 ( 4.3A)NAG A 505 (-4.5A)NAG A 504 (-3.7A)NAG A 504 (-3.8A)NAG A 503 (-4.0A)NAG A 504 (-4.5A)NAG A 504 (-3.5A)NAG A 505 (-4.1A)NAG A 504 (-3.6A) | 0.54A | 2a3cB-5wvbA:45.4 | 2a3cB-5wvbA:10.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvg | CHITINASE (Ostriniafurnacalis) |
no annotation | 9 | TRP A 538PHE A 565GLY A 605ASP A 645MET A 713TYR A 715ASP A 716TYR A 770TRP A 864 | NAG A1001 (-4.0A)NAG A1003 ( 4.8A)NAG A1003 (-3.5A)NAG A1003 (-3.9A)NAG A1003 (-3.6A)NAG A1003 (-4.5A)NAG A1003 (-3.1A)NAG A1002 (-4.2A)NAG A1003 (-3.4A) | 0.43A | 2a3cB-5wvgA:43.7 | 2a3cB-5wvgA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xep | CHITINASE-3-LIKEPROTEIN 1 (Mus musculus) |
no annotation | 6 | TRP A 31PHE A 58GLY A 99MET A 205TYR A 207TRP A 353 | None | 0.71A | 2a3cB-5xepA:43.8 | 2a3cB-5xepA:11.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 8 | TRP A 86PHE A 104GLY A 141ASP A 180GLU A 182MET A 254TYR A 256TRP A 425 | None | 0.98A | 2a3cB-5xwqA:10.0 | 2a3cB-5xwqA:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 8 | TRP A 86PHE A 104GLY A 141ASP A 180MET A 254TYR A 256TYR A 310TRP A 425 | None | 0.81A | 2a3cB-5xwqA:10.0 | 2a3cB-5xwqA:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 8 | TRP A 86PHE A 104GLY A 141THR A 143GLU A 182MET A 254TYR A 256TRP A 425 | None | 0.74A | 2a3cB-5xwqA:10.0 | 2a3cB-5xwqA:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 9 | TRP A 86PHE A 104GLY A 141THR A 143MET A 254TYR A 256ASP A 257TYR A 310TRP A 425 | None | 0.45A | 2a3cB-5xwqA:10.0 | 2a3cB-5xwqA:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y29 | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 8 | TRP A1621PHE A1648GLY A1690ASP A1731GLU A1733MET A1801TYR A1803TRP A1961 | None | 1.01A | 2a3cB-5y29A:43.6 | 2a3cB-5y29A:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y29 | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 9 | TRP A1621PHE A1648GLY A1690ASP A1731MET A1801TYR A1803ASP A1804TYR A1856TRP A1961 | None | 0.80A | 2a3cB-5y29A:43.6 | 2a3cB-5y29A:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2a | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 7 | TRP A2067PHE A2094GLY A2137ASP A2178GLU A2180MET A2248TYR A2250 | None | 1.07A | 2a3cB-5y2aA:43.4 | 2a3cB-5y2aA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2a | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 6 | TRP A2067PHE A2094GLY A2137ASP A2178GLU A2180TRP A2398 | None | 1.24A | 2a3cB-5y2aA:43.4 | 2a3cB-5y2aA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2a | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 7 | TRP A2067PHE A2094GLY A2137ASP A2178MET A2248TYR A2250TYR A2303 | None | 0.89A | 2a3cB-5y2aA:43.4 | 2a3cB-5y2aA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2a | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 6 | TRP A2067PHE A2094GLY A2137ASP A2178TYR A2303TRP A2398 | None | 1.07A | 2a3cB-5y2aA:43.4 | 2a3cB-5y2aA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2a | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 6 | TRP A2067PHE A2094GLY A2137ASP A2251TYR A2303TRP A2398 | None | 0.73A | 2a3cB-5y2aA:43.4 | 2a3cB-5y2aA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2a | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 7 | TRP A2067PHE A2094GLY A2137MET A2248TYR A2250ASP A2251TYR A2303 | None | 0.47A | 2a3cB-5y2aA:43.4 | 2a3cB-5y2aA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 8 | TRP A 167PHE A 191GLY A 274ASP A 313GLU A 315MET A 390TYR A 392TRP A 541 | GOL A 707 (-4.0A)GOL A 706 (-4.9A)GOL A 706 ( 4.1A)GOL A 706 (-3.5A)GOL A 706 (-3.3A)GOL A 706 (-3.3A)GOL A 706 (-4.8A)GOL A 706 ( 3.8A) | 1.04A | 2a3cB-5zl9A:43.2 | 2a3cB-5zl9A:10.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 8 | TRP A 167PHE A 191GLY A 274ASP A 313MET A 390TYR A 392TYR A 446TRP A 541 | GOL A 707 (-4.0A)GOL A 706 (-4.9A)GOL A 706 ( 4.1A)GOL A 706 (-3.5A)GOL A 706 (-3.3A)GOL A 706 (-4.8A)GOL A 703 (-3.5A)GOL A 706 ( 3.8A) | 0.84A | 2a3cB-5zl9A:43.2 | 2a3cB-5zl9A:10.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 8 | TRP A 167PHE A 191GLY A 274THR A 276GLU A 315MET A 390TYR A 392TRP A 541 | GOL A 707 (-4.0A)GOL A 706 (-4.9A)GOL A 706 ( 4.1A)NoneGOL A 706 (-3.3A)GOL A 706 (-3.3A)GOL A 706 (-4.8A)GOL A 706 ( 3.8A) | 0.83A | 2a3cB-5zl9A:43.2 | 2a3cB-5zl9A:10.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zl9 | CHITINASE AB (Serratiamarcescens) |
no annotation | 9 | TRP A 167PHE A 191GLY A 274THR A 276MET A 390TYR A 392ASP A 393TYR A 446TRP A 541 | GOL A 707 (-4.0A)GOL A 706 (-4.9A)GOL A 706 ( 4.1A)NoneGOL A 706 (-3.3A)GOL A 706 (-4.8A)GOL A 703 (-3.0A)GOL A 703 (-3.5A)GOL A 706 ( 3.8A) | 0.48A | 2a3cB-5zl9A:43.2 | 2a3cB-5zl9A:10.86 |