SIMILAR PATTERNS OF AMINO ACIDS FOR 1ZZQ_B_MTLB871
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1goj | KINESIN HEAVY CHAIN (Neurosporacrassa) |
PF00225(Kinesin) | 4 | SER A 308ARG A 15PHE A 14ASN A 313 | None | 1.33A | 1zzqB-1gojA:0.0 | 1zzqB-1gojA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iw8 | ACID PHOSPHATASE (Shimwelliablattae) |
PF01569(PAP2) | 4 | ASN A 211GLN A 216PHE A 214ASN A 101 | None | 1.32A | 1zzqB-1iw8A:0.0 | 1zzqB-1iw8A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1knr | L-ASPARTATE OXIDASE (Escherichiacoli) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | SER A 208ASN A 241GLN A 242ASN A 216 | NoneNoneNoneFAD A 800 (-4.1A) | 1.08A | 1zzqB-1knrA:0.0 | 1zzqB-1knrA:22.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lzx | NITRIC-OXIDESYNTHASE (Rattusnorvegicus) |
PF02898(NO_synthase) | 8 | SER A 477ARG A 481ASN A 498GLN A 500PHE A 501ASN A 569ASP A 709TRP A 711 | None | 0.60A | 1zzqB-1lzxA:62.7 | 1zzqB-1lzxA:99.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m9q | ENDOTHELIALNITRIC-OXIDESYNTHASE (Homo sapiens) |
PF02898(NO_synthase) | 5 | ARG A 250ASN A 267ASN A 338ASP A 478TRP A 480 | None | 0.70A | 1zzqB-1m9qA:59.2 | 1zzqB-1m9qA:65.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m9q | ENDOTHELIALNITRIC-OXIDESYNTHASE (Homo sapiens) |
PF02898(NO_synthase) | 4 | SER A 246ARG A 250ASN A 267ASN A 338 | None | 0.86A | 1zzqB-1m9qA:59.2 | 1zzqB-1m9qA:65.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mpo | MALTOPORIN (Escherichiacoli) |
PF02264(LamB) | 4 | ARG A 109GLN A 87ASN A 63ASP A 61 | GLC A 432 (-3.3A)NoneNoneNone | 1.18A | 1zzqB-1mpoA:0.0 | 1zzqB-1mpoA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1olp | ALPHA-TOXIN (Clostridiumsardiniense) |
PF00882(Zn_dep_PLPC)PF01477(PLAT) | 4 | SER A 96ARG A 99ASN A 93ASP A 92 | None | 1.12A | 1zzqB-1olpA:undetectable | 1zzqB-1olpA:21.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qw5 | NITRIC OXIDESYNTHASE, INDUCIBLE (Mus musculus) |
PF02898(NO_synthase) | 5 | SER A 256ARG A 260PHE A 280ASN A 348TRP A 490 | None | 0.78A | 1zzqB-1qw5A:58.1 | 1zzqB-1qw5A:63.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1twb | STRINGENT STARVATIONPROTEIN B HOMOLOG (Haemophilusinfluenzae) |
PF04386(SspB) | 4 | ASN A 72GLN A 63PHE A 71ASN A 39 | None | 1.07A | 1zzqB-1twbA:0.0 | 1zzqB-1twbA:14.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwy | CARBOXYPEPTIDASE M (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | SER A 197ASN A 185GLN A 249PHE A 183 | None | 1.23A | 1zzqB-1uwyA:undetectable | 1zzqB-1uwyA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrq | SARCOSINE OXIDASEALPHA SUBUNIT (Corynebacteriumsp. U-96) |
PF01571(GCV_T)PF08669(GCV_T_C)PF12831(FAD_oxidored)PF13510(Fer2_4) | 4 | ARG A 253ASN A 381PHE A 403ASP A 397 | None | 1.16A | 1zzqB-1vrqA:undetectable | 1zzqB-1vrqA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yni | SUCCINYLARGININEDIHYDROLASE (Escherichiacoli) |
PF04996(AstB) | 4 | ARG A 212ASN A 134GLN A 167ASN A 110 | SUG A1001 (-3.0A)NoneNoneSUG A1001 (-3.2A) | 1.28A | 1zzqB-1yniA:undetectable | 1zzqB-1yniA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytm | PHOSPHOENOLPYRUVATECARBOXYKINASE [ATP] (Anaerobiospirillumsucciniciproducens) |
PF01293(PEPCK_ATP) | 4 | SER A 379ASN A 514GLN A 512PHE A 511 | None | 1.27A | 1zzqB-1ytmA:undetectable | 1zzqB-1ytmA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yvl | SIGNAL TRANSDUCERAND ACTIVATOR OFTRANSCRIPTION1-ALPHA/BETA (Homo sapiens) |
PF00017(SH2)PF01017(STAT_alpha)PF02864(STAT_bind)PF02865(STAT_int) | 4 | GLN A 95PHE A 94ASN A 89ASP A 92 | None | 1.32A | 1zzqB-1yvlA:undetectable | 1zzqB-1yvlA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aqw | PUTATIVEOROTIDINE-MONOPHOSPHATE-DECARBOXYLASE (Plasmodiumyoelii) |
PF00215(OMPdecase) | 4 | SER A 202ASN A 207PHE A 203ASN A 199 | None | 1.15A | 1zzqB-2aqwA:undetectable | 1zzqB-2aqwA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bf6 | EXO-ALPHA-SIALIDASE (Clostridiumperfringens) |
PF13088(BNR_2) | 4 | ARG A 517ASN A 514GLN A 493ASN A 562 | NoneNoneSIA A1692 (-3.0A)None | 1.10A | 1zzqB-2bf6A:undetectable | 1zzqB-2bf6A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1g | ACID PHOSPHATASE (Francisellatularensis) |
PF04185(Phosphoesterase) | 4 | SER A 281ASN A 275GLN A 347ASP A 283 | NoneNoneETX A1006 (-3.5A)None | 1.28A | 1zzqB-2d1gA:undetectable | 1zzqB-2d1gA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gv0 | LYSOZYME C (Pelodiscussinensis) |
PF00062(Lys) | 4 | SER A 62GLN A 51ASN A 61ASP A 50 | None | 1.16A | 1zzqB-2gv0A:undetectable | 1zzqB-2gv0A:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hfs | MEVALONATE KINASE,PUTATIVE (Leishmaniamajor) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | SER A 152ARG A 169PHE A 176ASP A 155 | None | 1.31A | 1zzqB-2hfsA:1.0 | 1zzqB-2hfsA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ji9 | OXALYL-COADECARBOXYLASE (Oxalobacterformigenes) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | SER A 136ARG A 130GLN A 125ASP A 167 | None | 1.28A | 1zzqB-2ji9A:undetectable | 1zzqB-2ji9A:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jxy | MACROPHAGEMETALLOELASTASE (Homo sapiens) |
PF00045(Hemopexin) | 4 | SER A 464PHE A 300ASN A 465TRP A 307 | None | 1.09A | 1zzqB-2jxyA:undetectable | 1zzqB-2jxyA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kcy | 30S RIBOSOMALPROTEIN S8E (Methanothermobacterthermautotrophicus) |
PF01201(Ribosomal_S8e) | 4 | SER A 75ARG A 76ASN A 84ASP A 80 | None | 1.23A | 1zzqB-2kcyA:undetectable | 1zzqB-2kcyA:12.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mpr | MALTOPORIN (Salmonellaenterica) |
PF02264(LamB) | 4 | ARG A 109GLN A 87ASN A 63ASP A 61 | GLC A 429 ( 3.0A)NoneNoneNone | 1.11A | 1zzqB-2mprA:undetectable | 1zzqB-2mprA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p24 | H-2 CLASS IIHISTOCOMPATIBILITYANTIGEN, A-U ALPHACHAINH-2 CLASS IIHISTOCOMPATIBILITYANTIGEN, A-U BETACHAIN (Mus musculus;Mus musculus) |
PF00993(MHC_II_alpha)PF07654(C1-set)PF00969(MHC_II_beta)PF07654(C1-set) | 4 | SER A 144ARG B 134GLN A 88ASP A 110 | None | 1.16A | 1zzqB-2p24A:undetectable | 1zzqB-2p24A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjv | UNCHARACTERIZEDIOLB-LIKE PROTEIN (Salmonellaenterica) |
PF04962(KduI) | 4 | ARG A 190ASN A 217GLN A 195PHE A 191 | SO4 A 277 (-3.2A)SO4 A 277 (-3.5A)NoneNone | 0.99A | 1zzqB-2qjvA:undetectable | 1zzqB-2qjvA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r4g | TELOMERASE REVERSETRANSCRIPTASE (Tetrahymenathermophila) |
PF12009(Telomerase_RBD) | 4 | ASN A 317GLN A 282PHE A 318ASN A 322 | None | 1.27A | 1zzqB-2r4gA:undetectable | 1zzqB-2r4gA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xrc | HUMAN COMPLEMENTFACTOR I (Homo sapiens) |
PF00057(Ldl_recept_a)PF00089(Trypsin)PF00530(SRCR) | 4 | SER A 475ASN A 446GLN A 444ASN A 476 | NAG A 676 (-4.5A)NAG A 646 (-2.5A)NoneNAG A 676 (-2.5A) | 1.27A | 1zzqB-2xrcA:undetectable | 1zzqB-2xrcA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y5w | KINESIN HEAVY CHAIN (Drosophilamelanogaster) |
PF00225(Kinesin) | 4 | SER A 311ARG A 20PHE A 19ASN A 316 | None | 1.11A | 1zzqB-2y5wA:undetectable | 1zzqB-2y5wA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) |
PF03496(ADPrib_exo_Tox) | 4 | SER A 50GLN A 181PHE A 136ASN A 51 | None | 1.06A | 1zzqB-3buzA:undetectable | 1zzqB-3buzA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dal | PR DOMAIN ZINCFINGER PROTEIN 1 (Homo sapiens) |
PF00856(SET) | 4 | ARG A 75PHE A 76ASN A 26ASP A 27 | None | 0.97A | 1zzqB-3dalA:undetectable | 1zzqB-3dalA:19.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3e7g | NITRIC OXIDESYNTHASE, INDUCIBLE (Homo sapiens) |
PF02898(NO_synthase) | 4 | ARG A 266ASN A 283PHE A 286TRP A 496 | AT2 A 906 (-3.6A)NoneNoneNone | 1.15A | 1zzqB-3e7gA:57.4 | 1zzqB-3e7gA:65.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3e7g | NITRIC OXIDESYNTHASE, INDUCIBLE (Homo sapiens) |
PF02898(NO_synthase) | 4 | ASN A 283PHE A 286ASN A 354TRP A 496 | None | 1.03A | 1zzqB-3e7gA:57.4 | 1zzqB-3e7gA:65.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ecq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Streptococcuspneumoniae) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 4 | ARG A1163ASN A1161GLN A 623ASP A1254 | None | 1.27A | 1zzqB-3ecqA:undetectable | 1zzqB-3ecqA:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ek1 | ALDEHYDEDEHYDROGENASE (Brucellaabortus) |
PF00171(Aldedh) | 4 | ARG A 427GLN A 299ASN A 421ASP A 268 | None | 1.24A | 1zzqB-3ek1A:undetectable | 1zzqB-3ek1A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fzy | RTX TOXIN RTXA (Vibrio cholerae) |
PF11713(Peptidase_C80) | 4 | ARG A3530GLN A3582PHE A3579ASP A3537 | None | 1.20A | 1zzqB-3fzyA:undetectable | 1zzqB-3fzyA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i5g | MYOSIN REGULATORYLIGHT CHAIN LC-2,MANTLE MUSCLE (Todarodespacificus) |
PF13405(EF-hand_6) | 4 | ASN B 138GLN B 136PHE B 137ASP B 95 | None | 1.29A | 1zzqB-3i5gB:undetectable | 1zzqB-3i5gB:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihv | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | ASN A 384GLN A 382ASN A 523TRP A 515 | None | 1.07A | 1zzqB-3ihvA:undetectable | 1zzqB-3ihvA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ij3 | CYTOSOLAMINOPEPTIDASE (Coxiellaburnetii) |
PF00883(Peptidase_M17) | 4 | ARG A 122ASN A 117ASN A 154ASP A 151 | None | 1.20A | 1zzqB-3ij3A:undetectable | 1zzqB-3ij3A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ix1 | N-FORMYL-4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE BINDINGPROTEIN (Bacillushalodurans) |
PF09084(NMT1) | 4 | SER A 109ARG A 112ASN A 289PHE A 294 | None | 1.28A | 1zzqB-3ix1A:undetectable | 1zzqB-3ix1A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8v | FLAGELLIN HOMOLOG (Sphingomonassp. A1) |
PF00669(Flagellin_N)PF00700(Flagellin_C)PF07196(Flagellin_IN) | 4 | SER A 86ARG A 311ASN A 308ASN A 87 | None | 1.30A | 1zzqB-3k8vA:undetectable | 1zzqB-3k8vA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kie | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | SER A 390ASN A 381GLN A 385PHE A 273 | None | 1.19A | 1zzqB-3kieA:undetectable | 1zzqB-3kieA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kin | KINESIN HEAVY CHAINKINESIN HEAVY CHAIN (Rattusnorvegicus;Rattusnorvegicus) |
PF00225(Kinesin)PF00225(Kinesin) | 4 | SER B 305ARG A 16PHE A 15ASN B 310 | None | 1.30A | 1zzqB-3kinB:undetectable | 1zzqB-3kinB:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lgi | PROTEASE DEGS (Escherichiacoli) |
PF13365(Trypsin_2) | 4 | ARG A 77ASN A 63GLN A 103ASN A 67 | None | 1.32A | 1zzqB-3lgiA:undetectable | 1zzqB-3lgiA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lrv | PRE-MRNA-SPLICINGFACTOR 19 (Saccharomycescerevisiae) |
no annotation | 4 | ASN A 497PHE A 496ASN A 187ASP A 494 | NoneNoneSO4 A 69 (-4.3A)None | 1.30A | 1zzqB-3lrvA:undetectable | 1zzqB-3lrvA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mos | TRANSKETOLASE (Homo sapiens) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | SER A 345ARG A 318GLN A 428ASN A 344 | None | 1.14A | 1zzqB-3mosA:undetectable | 1zzqB-3mosA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvl | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Trypanosomabrucei) |
PF01676(Metalloenzyme)PF06415(iPGM_N) | 4 | SER A 74ASN A 419GLN A 355ASP A 319 | CO A 553 (-2.2A)NoneNone CO A 554 (-2.4A) | 1.00A | 1zzqB-3nvlA:undetectable | 1zzqB-3nvlA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otx | ADENOSINE KINASE,PUTATIVE (Trypanosomabrucei) |
PF00294(PfkB) | 4 | SER A 167ASN A 13ASN A 195ASP A 299 | NoneAP5 A 346 (-4.1A)NoneAP5 A 346 ( 3.2A) | 0.93A | 1zzqB-3otxA:undetectable | 1zzqB-3otxA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pgl | CARBOXY-TERMINALDOMAIN RNAPOLYMERASE IIPOLYPEPTIDE A SMALLPHOSPHATASE 1 (Homo sapiens) |
PF03031(NIF) | 4 | SER A 208ASN A 187ASN A 207ASP A 96 | NoneNone MG A 1 (-2.7A) MG A 1 (-2.5A) | 0.98A | 1zzqB-3pglA:undetectable | 1zzqB-3pglA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ra2 | CAPSID PROTEIN (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | SER A 393ASN A 384GLN A 388PHE A 276 | None | 1.24A | 1zzqB-3ra2A:undetectable | 1zzqB-3ra2A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t24 | PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | SER A 123ARG A 124GLN A 128ASP A 285 | SO4 A 397 (-2.4A)SO4 A 397 ( 3.7A)NoneNone | 1.26A | 1zzqB-3t24A:undetectable | 1zzqB-3t24A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3to3 | PETROBACTINBIOSYNTHESIS PROTEINASBB (Bacillusanthracis) |
PF04183(IucA_IucC)PF06276(FhuF) | 4 | ASN A 175GLN A 171PHE A 170ASN A 303 | None | 1.18A | 1zzqB-3to3A:undetectable | 1zzqB-3to3A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ux1 | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | SER A 392ASN A 383GLN A 387PHE A 275 | None | 1.19A | 1zzqB-3ux1A:undetectable | 1zzqB-3ux1A:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aw7 | GH86ABETA-PORPHYRANASE (Bacteroidesplebeius) |
no annotation | 4 | ARG A 249ASN A 253PHE A 555ASP A 208 | None | 1.29A | 1zzqB-4aw7A:undetectable | 1zzqB-4aw7A:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d0k | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN3-LIKE PROTEIN (Chaetomiumthermophilum) |
no annotation | 4 | SER B 538ARG B 540GLN B 484ASN B 523 | None | 1.12A | 1zzqB-4d0kB:undetectable | 1zzqB-4d0kB:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f92 | U5 SMALL NUCLEARRIBONUCLEOPROTEIN200 KDA HELICASE (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | ASN B 912GLN B 980PHE B 979ASP B 973 | None | 1.12A | 1zzqB-4f92B:undetectable | 1zzqB-4f92B:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gr6 | ATRBCX2 (Arabidopsisthaliana) |
PF02341(RcbX) | 4 | ARG A 80PHE A 61ASN A 21ASP A 57 | None | 1.26A | 1zzqB-4gr6A:undetectable | 1zzqB-4gr6A:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 4 | SER A 257ARG A 179GLN A 115ASN A 258 | None | 1.20A | 1zzqB-4ineA:undetectable | 1zzqB-4ineA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irx | SUGAR ABCTRANSPORTER,PERIPLASMICSUGAR-BINDINGPROTEIN (Caulobactervibrioides) |
PF13407(Peripla_BP_4) | 4 | ASN A 231GLN A 278ASN A 45ASP A 125 | INS A 401 (-3.9A)INS A 401 (-3.1A)NoneINS A 401 (-2.8A) | 1.22A | 1zzqB-4irxA:undetectable | 1zzqB-4irxA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m00 | SERINE-RICH ADHESINFOR PLATELETS (Staphylococcusaureus) |
PF05345(He_PIG) | 4 | ASN A 275GLN A 482ASN A 347ASP A 330 | NoneNoneNoneSUC A 804 (-3.3A) | 1.25A | 1zzqB-4m00A:undetectable | 1zzqB-4m00A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m01 | SERINE-RICH ADHESINFOR PLATELETS (Staphylococcusaureus) |
no annotation | 4 | ASN A 275GLN A 482ASN A 347ASP A 330 | NoneNoneNoneGOL A 602 (-3.3A) | 1.23A | 1zzqB-4m01A:undetectable | 1zzqB-4m01A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n4r | LPS-ASSEMBLY PROTEINLPTD (Salmonellaenterica) |
PF04453(OstA_C) | 4 | SER A 387GLN A 378PHE A 377ASN A 419 | None | 1.17A | 1zzqB-4n4rA:undetectable | 1zzqB-4n4rA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oav | PROTEIN (RNASE L) (Homo sapiens) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A)PF12796(Ank_2)PF13857(Ank_5) | 4 | ARG B 597GLN B 693PHE B 692ASP B 687 | None | 1.27A | 1zzqB-4oavB:undetectable | 1zzqB-4oavB:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oi3 | NICKEL RESPONSIVEPROTEIN (Streptomycescoelicolor) |
PF14026(DUF4242) | 4 | SER A 53GLN A 62PHE A 4ASP A 6 | None | 1.12A | 1zzqB-4oi3A:undetectable | 1zzqB-4oi3A:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pl0 | MICROCIN-J25 EXPORTATP-BINDING/PERMEASEPROTEIN MCJD (Escherichiacoli) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | ARG A 141ASN A 142ASN A 134ASP A 135 | None | 1.33A | 1zzqB-4pl0A:undetectable | 1zzqB-4pl0A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvi | GH62 HYDROLASE (Mycothermusthermophilus) |
PF03664(Glyco_hydro_62) | 4 | ASN A -6GLN A -2PHE A -3TRP A 32 | None | 1.32A | 1zzqB-4pviA:undetectable | 1zzqB-4pviA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASEDNA-DIRECTED RNAPOLYMERASE SUBUNIT N (Thermococcuskodakarensis;Thermococcuskodakarensis) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF01194(RNA_pol_N) | 4 | SER B 746ARG B 749PHE N 8ASN B 743 | None | 1.21A | 1zzqB-4qiwB:undetectable | 1zzqB-4qiwB:15.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3f | SPLICEOSOMAL PROTEINCWC27 (Chaetomiumthermophilum) |
PF00160(Pro_isomerase) | 4 | SER A 77ASN A 107PHE A 108TRP A 91 | None | 1.30A | 1zzqB-4r3fA:undetectable | 1zzqB-4r3fA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rso | CAPSID PROTEIN VP1 (Non-humanprimateAdeno-associatedvirus) |
PF00740(Parvo_coat) | 4 | SER A 392ASN A 383GLN A 387PHE A 275 | None | 1.18A | 1zzqB-4rsoA:undetectable | 1zzqB-4rsoA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uac | CARBOHYDRATE ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN, CUT1 FAMILY(TC 3.A.1.1.-) ([Eubacterium]rectale) |
PF13416(SBP_bac_8) | 4 | GLN A 394PHE A 189ASN A 191ASP A 190 | EDO A 504 (-3.3A)NoneACR A 501 (-3.3A)EDO A 504 ( 4.2A) | 1.22A | 1zzqB-4uacA:undetectable | 1zzqB-4uacA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzz | TRAP TRANSPORTERSOLUTE BINDINGPROTEIN (Bordetellabronchiseptica) |
PF03480(DctP) | 4 | GLN A 264PHE A 267ASN A 149TRP A 256 | None | 1.26A | 1zzqB-4yzzA:undetectable | 1zzqB-4yzzA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a08 | PROBABLEMANNOSYLTRANSFERASEKTR4 (Saccharomycescerevisiae) |
PF01793(Glyco_transf_15) | 4 | PHE A 241ASN A 172ASP A 173TRP A 204 | None | 1.33A | 1zzqB-5a08A:undetectable | 1zzqB-5a08A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 4 | SER A 116ASN A 174PHE A 89ASP A 122 | None | 1.10A | 1zzqB-5aexA:undetectable | 1zzqB-5aexA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eb2 | YFIR (Pseudomonasaeruginosa) |
PF13689(DUF4154) | 4 | SER A 168ARG A 171PHE A 127ASN A 165 | None | 1.29A | 1zzqB-5eb2A:undetectable | 1zzqB-5eb2A:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqn | FRBJ (Streptomycesrubellomurinus) |
PF02668(TauD) | 4 | ARG A 203GLN A 115ASP A 152TRP A 311 | NoneNone MG A 401 (-3.5A)None | 1.19A | 1zzqB-5eqnA:undetectable | 1zzqB-5eqnA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5haf | DEUBIQUITINASE SSEL (Salmonellaenterica) |
no annotation | 4 | ARG A 331ASN A 327GLN A 323PHE A 326 | None | 1.22A | 1zzqB-5hafA:undetectable | 1zzqB-5hafA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hnz | PROTEIN CLARETSEGREGATIONAL,PROTEIN CLARETSEGREGATIONAL,PLUS-END DIRECTEDKINESIN-1/KINESIN-14,PROTEIN CLARETSEGREGATIONAL,PROTEIN CLARETSEGREGATIONAL (Drosophilamelanogaster;Rattusnorvegicus) |
PF00225(Kinesin) | 4 | SER K 319ARG K 32PHE K 31ASN K 324 | None | 1.13A | 1zzqB-5hnzK:undetectable | 1zzqB-5hnzK:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5imw | INTERMEDILYSIN (Streptococcusintermedius) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | SER A 119ARG A 254ASN A 252ASP A 226 | None | 1.05A | 1zzqB-5imwA:undetectable | 1zzqB-5imwA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5imy | VAGINOLYSIN (Gardnerellavaginalis) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | SER A 133PHE A 121ASN A 126ASP A 124 | None | 1.29A | 1zzqB-5imyA:undetectable | 1zzqB-5imyA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iv8 | LPS BIOSYNTHESISPROTEIN (Klebsiellapneumoniae) |
PF04453(OstA_C) | 4 | SER A 386GLN A 356PHE A 376ASN A 418 | None | 1.18A | 1zzqB-5iv8A:undetectable | 1zzqB-5iv8A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j55 | CAROTENOID OXYGENASE (Novosphingobiumaromaticivorans) |
PF03055(RPE65) | 4 | ARG A 356GLN A 417PHE A 354ASN A 122 | None | 1.01A | 1zzqB-5j55A:undetectable | 1zzqB-5j55A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kc1 | AUTOPHAGY-RELATEDPROTEIN 38 (Saccharomycescerevisiae) |
no annotation | 4 | ARG C 137ASN C 141GLN C 139PHE C 140 | NO3 C 302 ( 3.4A) NA C 301 (-4.3A)NoneNone | 1.31A | 1zzqB-5kc1C:undetectable | 1zzqB-5kc1C:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kzs | PUTATIVE CELLSURFACE PROTEIN,SIMILAR TOINTERNALIN PROTEINS (Listeriamonocytogenes) |
PF12354(Internalin_N)PF13855(LRR_8) | 4 | GLN A 346PHE A 347ASN A 303ASP A 349 | None | 1.32A | 1zzqB-5kzsA:undetectable | 1zzqB-5kzsA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lii | MAJOR CAPSID PROTEIN (Staphylococcusphage 812) |
no annotation | 4 | ASN P 247GLN P 237ASN P 242ASP P 241 | None | 1.29A | 1zzqB-5liiP:undetectable | 1zzqB-5liiP:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lt1 | KINESIN-LIKE PROTEIN (Homo sapiens) |
PF00225(Kinesin) | 4 | SER A 303ARG A 16ASN A 308ASP A 27 | None | 1.32A | 1zzqB-5lt1A:undetectable | 1zzqB-5lt1A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lt1 | KINESIN-LIKE PROTEIN (Homo sapiens) |
PF00225(Kinesin) | 4 | SER A 303ARG A 16PHE A 15ASN A 308 | None | 1.16A | 1zzqB-5lt1A:undetectable | 1zzqB-5lt1A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfi | MINOR FIMBRIUMANCHORING SUBUNITMFA2 (Porphyromonasgingivalis) |
no annotation | 4 | ARG B 175ASN B 47PHE B 48ASN B 177 | None | 1.28A | 1zzqB-5nfiB:undetectable | 1zzqB-5nfiB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqr | CONDENSIN COMPLEXSUBUNIT 3 (Schizosaccharomycespombe) |
no annotation | 4 | SER A 188ARG A 160PHE A 192ASN A 187 | None | 1.29A | 1zzqB-5oqrA:undetectable | 1zzqB-5oqrA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t4y | SUSC HOMOLOG (Bacteroidesthetaiotaomicron) |
no annotation | 4 | SER D 343ASN D 309GLN D 307ASN D 366 | None | 1.10A | 1zzqB-5t4yD:undetectable | 1zzqB-5t4yD:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1d | ANTIGEN PEPTIDETRANSPORTER 2TAP TRANSPORTERINHIBITOR ICP47 (Homo sapiens;Humanalphaherpesvirus1) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF05363(Herpes_US12) | 4 | SER B 254ARG B 226ASN B 222ASP X 36 | None | 1.33A | 1zzqB-5u1dB:undetectable | 1zzqB-5u1dB:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ubw | DEUBIQUITINASE SSEL (Salmonellaenterica) |
no annotation | 4 | ARG A 331ASN A 327GLN A 323PHE A 326 | None | 1.14A | 1zzqB-5ubwA:undetectable | 1zzqB-5ubwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5un1 | N-METHYL-D-ASPARTATERECEPTOR SUBUNITNR1-3A (Xenopus laevis) |
no annotation | 4 | SER G 678ARG G 521ASN G 518ASP G 722 | GLY G1001 (-3.4A)GLY G1001 (-2.7A)NoneGLY G1001 (-3.0A) | 1.32A | 1zzqB-5un1G:undetectable | 1zzqB-5un1G:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgb | CRISPR-ASSOCIATEDENDONUCLEASE CAS9ANTI-CRISPR PROTEIN(ACRIIC1) (Neisseriameningitidis;Neisseriameningitidis) |
PF13395(HNH_4)no annotation | 4 | ASN A 88PHE A 87ASN A 13ASP B 44 | SO4 A 203 (-3.9A)NoneNoneNone | 1.15A | 1zzqB-5vgbA:undetectable | 1zzqB-5vgbA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3f | TUBULIN ALPHA-1CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 4 | SER A 224GLN A 15PHE A 225ASN A 227 | NoneNoneGTP A 502 (-3.8A)None | 1.07A | 1zzqB-5w3fA:undetectable | 1zzqB-5w3fA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xb6 | UNCHARACTERIZEDPROTEIN YCJY (Escherichiacoli) |
no annotation | 4 | SER A 146ARG A 149ASN A 143ASP A 261 | None | 0.89A | 1zzqB-5xb6A:undetectable | 1zzqB-5xb6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjg | VACUOLAR PROTEIN 8NUCLEUS-VACUOLEJUNCTION PROTEIN 1 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00514(Arm)no annotation | 4 | SER A 280ARG A 242GLN B 308ASN B 304 | None | 0.82A | 1zzqB-5xjgA:undetectable | 1zzqB-5xjgA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yh5 | NICKEL ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN (Staphylococcusaureus) |
no annotation | 4 | ASN A 450GLN A 130ASN A 310ASP A 308 | None | 1.20A | 1zzqB-5yh5A:undetectable | 1zzqB-5yh5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bo6 | - (-) |
no annotation | 4 | SER A 569ASN A 148GLN A 166ASP A 61 | None | 1.30A | 1zzqB-6bo6A:undetectable | 1zzqB-6bo6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6evj | RNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Avirus) |
no annotation | 4 | SER B 345ARG B 316ASN B 314ASN B 346 | None | 1.26A | 1zzqB-6evjB:undetectable | 1zzqB-6evjB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0k | FE-S-CLUSTER-CONTAINING HYDROGENASEPOLYSULPHIDEREDUCTASE NRFDQUINOL:CYTOCHROME COXIDOREDUCTASEMONOHEME CYTOCHROMESUBUNIT (Rhodothermusmarinus;Rhodothermusmarinus;Rhodothermusmarinus) |
no annotationno annotationno annotation | 4 | ARG C 142PHE B 939ASN E 37ASP E 41 | NoneNoneHEC A 301 (-2.9A)None | 1.15A | 1zzqB-6f0kC:undetectable | 1zzqB-6f0kC:undetectable |