SIMILAR PATTERNS OF AMINO ACIDS FOR 1ZZQ_A_MTLA870_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c9l | CLATHRIN (Rattusnorvegicus) |
PF01394(Clathrin_propel)PF09268(Clathrin-link) | 4 | SER A 200ARG A 157GLN A 203PHE A 201 | None | 1.34A | 1zzqA-1c9lA:0.0 | 1zzqA-1c9lA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ehx | SCAFFOLDIN PROTEIN ([Clostridium]cellulolyticum) |
PF03442(CBM_X2) | 4 | GLN A 2PHE A 72ASN A 28ASP A 3 | None | 1.31A | 1zzqA-1ehxA:undetectable | 1zzqA-1ehxA:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iw8 | ACID PHOSPHATASE (Shimwelliablattae) |
PF01569(PAP2) | 4 | ASN A 211GLN A 216PHE A 214ASN A 101 | None | 1.31A | 1zzqA-1iw8A:0.0 | 1zzqA-1iw8A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1knr | L-ASPARTATE OXIDASE (Escherichiacoli) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | SER A 208ASN A 241GLN A 242ASN A 216 | NoneNoneNoneFAD A 800 (-4.1A) | 1.04A | 1zzqA-1knrA:0.0 | 1zzqA-1knrA:22.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lzx | NITRIC-OXIDESYNTHASE (Rattusnorvegicus) |
PF02898(NO_synthase) | 8 | SER A 477ARG A 481ASN A 498GLN A 500PHE A 501ASN A 569ASP A 709TRP A 711 | None | 0.52A | 1zzqA-1lzxA:64.4 | 1zzqA-1lzxA:99.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m9q | ENDOTHELIALNITRIC-OXIDESYNTHASE (Homo sapiens) |
PF02898(NO_synthase) | 5 | ARG A 250ASN A 267ASN A 338ASP A 478TRP A 480 | None | 0.64A | 1zzqA-1m9qA:59.6 | 1zzqA-1m9qA:65.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m9q | ENDOTHELIALNITRIC-OXIDESYNTHASE (Homo sapiens) |
PF02898(NO_synthase) | 4 | SER A 246ARG A 250ASN A 267ASN A 338 | None | 0.73A | 1zzqA-1m9qA:59.6 | 1zzqA-1m9qA:65.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mpo | MALTOPORIN (Escherichiacoli) |
PF02264(LamB) | 4 | ARG A 109GLN A 87ASN A 63ASP A 61 | GLC A 432 (-3.3A)NoneNoneNone | 1.31A | 1zzqA-1mpoA:0.0 | 1zzqA-1mpoA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1olp | ALPHA-TOXIN (Clostridiumsardiniense) |
PF00882(Zn_dep_PLPC)PF01477(PLAT) | 4 | SER A 96ARG A 99ASN A 93ASP A 92 | None | 1.15A | 1zzqA-1olpA:undetectable | 1zzqA-1olpA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgi | PROTEIN(CHITOSANASE) (Bacilluscirculans) |
PF01374(Glyco_hydro_46) | 4 | ASN A 224GLN A 231ASN A 176ASP A 172 | None | 1.36A | 1zzqA-1qgiA:0.0 | 1zzqA-1qgiA:19.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qw5 | NITRIC OXIDESYNTHASE, INDUCIBLE (Mus musculus) |
PF02898(NO_synthase) | 5 | SER A 256ARG A 260PHE A 280ASN A 348TRP A 490 | None | 0.75A | 1zzqA-1qw5A:58.0 | 1zzqA-1qw5A:63.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sgf | NERVE GROWTH FACTOR (Mus musculus) |
PF00089(Trypsin) | 4 | SER A 95GLN A 95ASN A 95ASP A 97 | NAG A 11 (-3.4A)NoneNAG A 11 (-2.0A)NAG A 11 (-4.2A) | 1.33A | 1zzqA-1sgfA:undetectable | 1zzqA-1sgfA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1twb | STRINGENT STARVATIONPROTEIN B HOMOLOG (Haemophilusinfluenzae) |
PF04386(SspB) | 4 | ASN A 72GLN A 63PHE A 71ASN A 39 | None | 1.02A | 1zzqA-1twbA:undetectable | 1zzqA-1twbA:14.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwy | CARBOXYPEPTIDASE M (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | SER A 197ASN A 185GLN A 249PHE A 183 | None | 1.26A | 1zzqA-1uwyA:undetectable | 1zzqA-1uwyA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wra | TEICHOIC ACIDPHOSPHORYLCHOLINEESTERASE/CHOLINEBINDING PROTEIN E(CBPE) (Streptococcuspneumoniae) |
PF00753(Lactamase_B) | 4 | SER A 50GLN A 180PHE A 181ASN A 31 | None | 1.07A | 1zzqA-1wraA:undetectable | 1zzqA-1wraA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yni | SUCCINYLARGININEDIHYDROLASE (Escherichiacoli) |
PF04996(AstB) | 4 | ARG A 212ASN A 134GLN A 167ASN A 110 | SUG A1001 (-3.0A)NoneNoneSUG A1001 (-3.2A) | 1.30A | 1zzqA-1yniA:undetectable | 1zzqA-1yniA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytm | PHOSPHOENOLPYRUVATECARBOXYKINASE [ATP] (Anaerobiospirillumsucciniciproducens) |
PF01293(PEPCK_ATP) | 4 | SER A 379ASN A 514GLN A 512PHE A 511 | None | 1.28A | 1zzqA-1ytmA:undetectable | 1zzqA-1ytmA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yvl | SIGNAL TRANSDUCERAND ACTIVATOR OFTRANSCRIPTION1-ALPHA/BETA (Homo sapiens) |
PF00017(SH2)PF01017(STAT_alpha)PF02864(STAT_bind)PF02865(STAT_int) | 4 | GLN A 95PHE A 94ASN A 89ASP A 92 | None | 1.25A | 1zzqA-1yvlA:undetectable | 1zzqA-1yvlA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aqw | PUTATIVEOROTIDINE-MONOPHOSPHATE-DECARBOXYLASE (Plasmodiumyoelii) |
PF00215(OMPdecase) | 4 | SER A 202ASN A 207PHE A 203ASN A 199 | None | 1.15A | 1zzqA-2aqwA:undetectable | 1zzqA-2aqwA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bf6 | EXO-ALPHA-SIALIDASE (Clostridiumperfringens) |
PF13088(BNR_2) | 4 | ARG A 517ASN A 514GLN A 493ASN A 562 | NoneNoneSIA A1692 (-3.0A)None | 1.17A | 1zzqA-2bf6A:undetectable | 1zzqA-2bf6A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bib | TEICHOIC ACIDPHOSPHORYLCHOLINEESTERASE/ CHOLINEBINDING PROTEIN (Streptococcuspneumoniae) |
PF00753(Lactamase_B)PF01473(CW_binding_1) | 4 | SER A 25GLN A 155PHE A 156ASN A 6 | None | 1.11A | 1zzqA-2bibA:undetectable | 1zzqA-2bibA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1g | ACID PHOSPHATASE (Francisellatularensis) |
PF04185(Phosphoesterase) | 4 | SER A 281ASN A 275GLN A 347ASP A 283 | NoneNoneETX A1006 (-3.5A)None | 1.30A | 1zzqA-2d1gA:undetectable | 1zzqA-2d1gA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5w | PEPTIDE ABCTRANSPORTER,PEPTIDE-BINDINGPROTEIN (Thermusthermophilus) |
PF00496(SBP_bac_5) | 4 | ARG A 550GLN A 279PHE A 277ASN A 552 | None | 1.23A | 1zzqA-2d5wA:undetectable | 1zzqA-2d5wA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gv0 | LYSOZYME C (Pelodiscussinensis) |
PF00062(Lys) | 4 | SER A 62GLN A 51ASN A 61ASP A 50 | None | 1.15A | 1zzqA-2gv0A:undetectable | 1zzqA-2gv0A:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jxy | MACROPHAGEMETALLOELASTASE (Homo sapiens) |
PF00045(Hemopexin) | 4 | SER A 464PHE A 300ASN A 465TRP A 307 | None | 1.12A | 1zzqA-2jxyA:undetectable | 1zzqA-2jxyA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kcy | 30S RIBOSOMALPROTEIN S8E (Methanothermobacterthermautotrophicus) |
PF01201(Ribosomal_S8e) | 4 | SER A 75ARG A 76ASN A 84ASP A 80 | None | 1.19A | 1zzqA-2kcyA:undetectable | 1zzqA-2kcyA:12.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kzb | AUTOPHAGY-RELATEDPROTEIN 19 (Saccharomycescerevisiae) |
PF12744(ATG19_autophagy) | 4 | SER A 261ARG A 359PHE A 346ASN A 280 | None | 1.36A | 1zzqA-2kzbA:undetectable | 1zzqA-2kzbA:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mpr | MALTOPORIN (Salmonellaenterica) |
PF02264(LamB) | 4 | ARG A 109GLN A 87ASN A 63ASP A 61 | GLC A 429 ( 3.0A)NoneNoneNone | 1.25A | 1zzqA-2mprA:undetectable | 1zzqA-2mprA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjv | UNCHARACTERIZEDIOLB-LIKE PROTEIN (Salmonellaenterica) |
PF04962(KduI) | 4 | ARG A 190ASN A 217GLN A 195PHE A 191 | SO4 A 277 (-3.2A)SO4 A 277 (-3.5A)NoneNone | 0.97A | 1zzqA-2qjvA:undetectable | 1zzqA-2qjvA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r4g | TELOMERASE REVERSETRANSCRIPTASE (Tetrahymenathermophila) |
PF12009(Telomerase_RBD) | 4 | ASN A 317GLN A 282PHE A 318ASN A 322 | None | 1.33A | 1zzqA-2r4gA:undetectable | 1zzqA-2r4gA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xrc | HUMAN COMPLEMENTFACTOR I (Homo sapiens) |
PF00057(Ldl_recept_a)PF00089(Trypsin)PF00530(SRCR) | 4 | SER A 475ASN A 446GLN A 444ASN A 476 | NAG A 676 (-4.5A)NAG A 646 (-2.5A)NoneNAG A 676 (-2.5A) | 1.30A | 1zzqA-2xrcA:undetectable | 1zzqA-2xrcA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y5w | KINESIN HEAVY CHAIN (Drosophilamelanogaster) |
PF00225(Kinesin) | 4 | SER A 311ARG A 20PHE A 19ASN A 316 | None | 1.15A | 1zzqA-2y5wA:undetectable | 1zzqA-2y5wA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3buz | IOTA TOXIN COMPONENTIA (Clostridiumperfringens) |
PF03496(ADPrib_exo_Tox) | 4 | SER A 50GLN A 181PHE A 136ASN A 51 | None | 1.08A | 1zzqA-3buzA:undetectable | 1zzqA-3buzA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dal | PR DOMAIN ZINCFINGER PROTEIN 1 (Homo sapiens) |
PF00856(SET) | 4 | ARG A 75PHE A 76ASN A 26ASP A 27 | None | 1.05A | 1zzqA-3dalA:undetectable | 1zzqA-3dalA:19.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3e7g | NITRIC OXIDESYNTHASE, INDUCIBLE (Homo sapiens) |
PF02898(NO_synthase) | 4 | ARG A 266ASN A 283PHE A 286TRP A 496 | AT2 A 906 (-3.6A)NoneNoneNone | 1.10A | 1zzqA-3e7gA:57.2 | 1zzqA-3e7gA:65.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3e7g | NITRIC OXIDESYNTHASE, INDUCIBLE (Homo sapiens) |
PF02898(NO_synthase) | 4 | ASN A 283PHE A 286ASN A 354TRP A 496 | None | 0.97A | 1zzqA-3e7gA:57.2 | 1zzqA-3e7gA:65.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ek1 | ALDEHYDEDEHYDROGENASE (Brucellaabortus) |
PF00171(Aldedh) | 4 | ARG A 427GLN A 299ASN A 421ASP A 268 | None | 1.23A | 1zzqA-3ek1A:undetectable | 1zzqA-3ek1A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fzy | RTX TOXIN RTXA (Vibrio cholerae) |
PF11713(Peptidase_C80) | 4 | ARG A3530GLN A3582PHE A3579ASP A3537 | None | 1.27A | 1zzqA-3fzyA:undetectable | 1zzqA-3fzyA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihv | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | ASN A 384GLN A 382ASN A 523TRP A 515 | None | 1.12A | 1zzqA-3ihvA:undetectable | 1zzqA-3ihvA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ij6 | UNCHARACTERIZEDMETAL-DEPENDENTHYDROLASE (Lactobacillusacidophilus) |
PF04909(Amidohydro_2) | 4 | ASN A 281GLN A 274ASN A 53ASP A 51 | None | 1.29A | 1zzqA-3ij6A:undetectable | 1zzqA-3ij6A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ix1 | N-FORMYL-4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE BINDINGPROTEIN (Bacillushalodurans) |
PF09084(NMT1) | 5 | SER A 109ARG A 112ASN A 289PHE A 294TRP A 239 | None | 1.37A | 1zzqA-3ix1A:undetectable | 1zzqA-3ix1A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kie | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | SER A 390ASN A 381GLN A 385PHE A 273 | None | 1.18A | 1zzqA-3kieA:undetectable | 1zzqA-3kieA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kin | KINESIN HEAVY CHAINKINESIN HEAVY CHAIN (Rattusnorvegicus;Rattusnorvegicus) |
PF00225(Kinesin)PF00225(Kinesin) | 4 | SER B 305ARG A 16PHE A 15ASN B 310 | None | 1.35A | 1zzqA-3kinB:undetectable | 1zzqA-3kinB:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mos | TRANSKETOLASE (Homo sapiens) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | SER A 345ARG A 318GLN A 428ASN A 344 | None | 1.14A | 1zzqA-3mosA:undetectable | 1zzqA-3mosA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvl | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Trypanosomabrucei) |
PF01676(Metalloenzyme)PF06415(iPGM_N) | 4 | SER A 74ASN A 419GLN A 355ASP A 319 | CO A 553 (-2.2A)NoneNone CO A 554 (-2.4A) | 1.08A | 1zzqA-3nvlA:undetectable | 1zzqA-3nvlA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otx | ADENOSINE KINASE,PUTATIVE (Trypanosomabrucei) |
PF00294(PfkB) | 4 | SER A 167ASN A 13ASN A 195ASP A 299 | NoneAP5 A 346 (-4.1A)NoneAP5 A 346 ( 3.2A) | 0.95A | 1zzqA-3otxA:undetectable | 1zzqA-3otxA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pgl | CARBOXY-TERMINALDOMAIN RNAPOLYMERASE IIPOLYPEPTIDE A SMALLPHOSPHATASE 1 (Homo sapiens) |
PF03031(NIF) | 4 | SER A 208ASN A 187ASN A 207ASP A 96 | NoneNone MG A 1 (-2.7A) MG A 1 (-2.5A) | 1.00A | 1zzqA-3pglA:undetectable | 1zzqA-3pglA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ra2 | CAPSID PROTEIN (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | SER A 393ASN A 384GLN A 388PHE A 276 | None | 1.23A | 1zzqA-3ra2A:undetectable | 1zzqA-3ra2A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t24 | PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | SER A 123ARG A 124GLN A 128ASP A 285 | SO4 A 397 (-2.4A)SO4 A 397 ( 3.7A)NoneNone | 1.23A | 1zzqA-3t24A:undetectable | 1zzqA-3t24A:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3to3 | PETROBACTINBIOSYNTHESIS PROTEINASBB (Bacillusanthracis) |
PF04183(IucA_IucC)PF06276(FhuF) | 4 | ASN A 175GLN A 171PHE A 170ASN A 303 | None | 1.11A | 1zzqA-3to3A:undetectable | 1zzqA-3to3A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbz | LIKELY HISTIDYLTRNA-SPECIFICGUANYLYLTRANSFERASE (Candidaalbicans) |
PF04446(Thg1)PF14413(Thg1C) | 4 | ARG A 143GLN A 150PHE A 146ASN A 144 | None | 1.36A | 1zzqA-3wbzA:undetectable | 1zzqA-3wbzA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d0k | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN3-LIKE PROTEIN (Chaetomiumthermophilum) |
no annotation | 4 | SER B 538ARG B 540GLN B 484ASN B 523 | None | 1.19A | 1zzqA-4d0kB:undetectable | 1zzqA-4d0kB:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f92 | U5 SMALL NUCLEARRIBONUCLEOPROTEIN200 KDA HELICASE (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | ARG B1375ASN B1444GLN B1446ASN B1449 | None | 1.29A | 1zzqA-4f92B:undetectable | 1zzqA-4f92B:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gdz | UNCHARACTERIZEDPROTEIN (Bacteroideseggerthii) |
PF14059(DUF4251) | 4 | SER A 181ASN A 73ASN A 161ASP A 160 | None | 1.33A | 1zzqA-4gdzA:undetectable | 1zzqA-4gdzA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 4 | SER A 257ARG A 179GLN A 115ASN A 258 | None | 1.19A | 1zzqA-4ineA:undetectable | 1zzqA-4ineA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irx | SUGAR ABCTRANSPORTER,PERIPLASMICSUGAR-BINDINGPROTEIN (Caulobactervibrioides) |
PF13407(Peripla_BP_4) | 4 | ASN A 231GLN A 278ASN A 45ASP A 125 | INS A 401 (-3.9A)INS A 401 (-3.1A)NoneINS A 401 (-2.8A) | 1.22A | 1zzqA-4irxA:undetectable | 1zzqA-4irxA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m01 | SERINE-RICH ADHESINFOR PLATELETS (Staphylococcusaureus) |
no annotation | 4 | ASN A 275GLN A 482ASN A 347ASP A 330 | NoneNoneNoneGOL A 602 (-3.3A) | 1.36A | 1zzqA-4m01A:undetectable | 1zzqA-4m01A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oav | PROTEIN (RNASE L) (Homo sapiens) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A)PF12796(Ank_2)PF13857(Ank_5) | 4 | ARG B 597GLN B 693PHE B 692ASP B 687 | None | 1.29A | 1zzqA-4oavB:undetectable | 1zzqA-4oavB:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oi3 | NICKEL RESPONSIVEPROTEIN (Streptomycescoelicolor) |
PF14026(DUF4242) | 4 | SER A 53GLN A 62PHE A 4ASP A 6 | None | 1.19A | 1zzqA-4oi3A:undetectable | 1zzqA-4oi3A:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pl0 | MICROCIN-J25 EXPORTATP-BINDING/PERMEASEPROTEIN MCJD (Escherichiacoli) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | ARG A 141ASN A 142ASN A 134ASP A 135 | None | 1.34A | 1zzqA-4pl0A:undetectable | 1zzqA-4pl0A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvi | GH62 HYDROLASE (Mycothermusthermophilus) |
PF03664(Glyco_hydro_62) | 4 | ASN A -6GLN A -2PHE A -3TRP A 32 | None | 1.23A | 1zzqA-4pviA:undetectable | 1zzqA-4pviA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASEDNA-DIRECTED RNAPOLYMERASE SUBUNIT N (Thermococcuskodakarensis;Thermococcuskodakarensis) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF01194(RNA_pol_N) | 4 | SER B 746ARG B 749PHE N 8ASN B 743 | None | 1.24A | 1zzqA-4qiwB:undetectable | 1zzqA-4qiwB:15.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3f | SPLICEOSOMAL PROTEINCWC27 (Chaetomiumthermophilum) |
PF00160(Pro_isomerase) | 4 | SER A 77ASN A 107PHE A 108TRP A 91 | None | 1.29A | 1zzqA-4r3fA:undetectable | 1zzqA-4r3fA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rso | CAPSID PROTEIN VP1 (Non-humanprimateAdeno-associatedvirus) |
PF00740(Parvo_coat) | 4 | SER A 392ASN A 383GLN A 387PHE A 275 | None | 1.18A | 1zzqA-4rsoA:undetectable | 1zzqA-4rsoA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uac | CARBOHYDRATE ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN, CUT1 FAMILY(TC 3.A.1.1.-) ([Eubacterium]rectale) |
PF13416(SBP_bac_8) | 4 | GLN A 394PHE A 189ASN A 191ASP A 190 | EDO A 504 (-3.3A)NoneACR A 501 (-3.3A)EDO A 504 ( 4.2A) | 1.27A | 1zzqA-4uacA:undetectable | 1zzqA-4uacA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzz | TRAP TRANSPORTERSOLUTE BINDINGPROTEIN (Bordetellabronchiseptica) |
PF03480(DctP) | 4 | GLN A 264PHE A 267ASN A 149TRP A 256 | None | 1.26A | 1zzqA-4yzzA:undetectable | 1zzqA-4yzzA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a08 | PROBABLEMANNOSYLTRANSFERASEKTR4 (Saccharomycescerevisiae) |
PF01793(Glyco_transf_15) | 4 | PHE A 241ASN A 172ASP A 173TRP A 204 | None | 1.30A | 1zzqA-5a08A:undetectable | 1zzqA-5a08A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aa5 | NIFE-HYDROGENASESMALL SUBUNIT, HOFK (Cupriavidusnecator) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | GLN A 263PHE A 223ASN A 182ASP A 214 | None | 1.33A | 1zzqA-5aa5A:undetectable | 1zzqA-5aa5A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 4 | SER A 116ASN A 174PHE A 89ASP A 122 | None | 1.13A | 1zzqA-5aexA:undetectable | 1zzqA-5aexA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ejj | UFM1-SPECIFICPROTEASE (Caenorhabditiselegans) |
PF07910(Peptidase_C78) | 4 | ASN A 72GLN A 74PHE A 75ASN A 288 | None | 1.14A | 1zzqA-5ejjA:undetectable | 1zzqA-5ejjA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqn | FRBJ (Streptomycesrubellomurinus) |
PF02668(TauD) | 4 | ARG A 203GLN A 115ASP A 152TRP A 311 | NoneNone MG A 401 (-3.5A)None | 1.08A | 1zzqA-5eqnA:undetectable | 1zzqA-5eqnA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5haf | DEUBIQUITINASE SSEL (Salmonellaenterica) |
no annotation | 4 | ARG A 331ASN A 327GLN A 323PHE A 326 | None | 1.27A | 1zzqA-5hafA:undetectable | 1zzqA-5hafA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hnz | PROTEIN CLARETSEGREGATIONAL,PROTEIN CLARETSEGREGATIONAL,PLUS-END DIRECTEDKINESIN-1/KINESIN-14,PROTEIN CLARETSEGREGATIONAL,PROTEIN CLARETSEGREGATIONAL (Drosophilamelanogaster;Rattusnorvegicus) |
PF00225(Kinesin) | 4 | SER K 319ARG K 32PHE K 31ASN K 324 | None | 1.17A | 1zzqA-5hnzK:undetectable | 1zzqA-5hnzK:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i4e | MYOSIN-14,ALPHA-ACTININ A (Homo sapiens;Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF00435(Spectrin)PF02736(Myosin_N) | 4 | GLN A 583PHE A 594ASN A 488ASP A 604 | None | 1.35A | 1zzqA-5i4eA:undetectable | 1zzqA-5i4eA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5imw | INTERMEDILYSIN (Streptococcusintermedius) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | SER A 119ARG A 254ASN A 252ASP A 226 | None | 1.03A | 1zzqA-5imwA:undetectable | 1zzqA-5imwA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5imy | VAGINOLYSIN (Gardnerellavaginalis) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 4 | SER A 133PHE A 121ASN A 126ASP A 124 | None | 1.30A | 1zzqA-5imyA:undetectable | 1zzqA-5imyA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iv8 | LPS BIOSYNTHESISPROTEIN (Klebsiellapneumoniae) |
PF04453(OstA_C) | 4 | SER A 386GLN A 356PHE A 376ASN A 418 | None | 1.18A | 1zzqA-5iv8A:undetectable | 1zzqA-5iv8A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j55 | CAROTENOID OXYGENASE (Novosphingobiumaromaticivorans) |
PF03055(RPE65) | 4 | ARG A 356GLN A 417PHE A 354ASN A 122 | None | 1.06A | 1zzqA-5j55A:undetectable | 1zzqA-5j55A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kd5 | METALLOPEPTIDASE (Bacteroidesthetaiotaomicron) |
PF13402(Peptidase_M60)PF17291(M60-like_N) | 4 | SER A 617GLN A 627ASN A 613ASP A 641 | EDO A 903 ( 4.3A)NoneEDO A 903 (-4.1A)None | 1.34A | 1zzqA-5kd5A:undetectable | 1zzqA-5kd5A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kxj | L-ASPARTATE OXIDASE (Salmonellaenterica) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | SER A 208ASN A 241GLN A 242PHE A 243 | None | 1.26A | 1zzqA-5kxjA:undetectable | 1zzqA-5kxjA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kzs | PUTATIVE CELLSURFACE PROTEIN,SIMILAR TOINTERNALIN PROTEINS (Listeriamonocytogenes) |
PF12354(Internalin_N)PF13855(LRR_8) | 4 | GLN A 346PHE A 347ASN A 303ASP A 349 | None | 1.32A | 1zzqA-5kzsA:undetectable | 1zzqA-5kzsA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lii | MAJOR CAPSID PROTEIN (Staphylococcusphage 812) |
no annotation | 4 | ASN P 247GLN P 237ASN P 242ASP P 241 | None | 1.24A | 1zzqA-5liiP:undetectable | 1zzqA-5liiP:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lt1 | KINESIN-LIKE PROTEIN (Homo sapiens) |
PF00225(Kinesin) | 4 | SER A 303ARG A 16PHE A 15ASN A 308 | None | 1.20A | 1zzqA-5lt1A:undetectable | 1zzqA-5lt1A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqr | CONDENSIN COMPLEXSUBUNIT 3 (Schizosaccharomycespombe) |
no annotation | 4 | SER A 188ARG A 160PHE A 192ASN A 187 | None | 1.34A | 1zzqA-5oqrA:undetectable | 1zzqA-5oqrA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t1q | N-ACETYLMURAMOYL-L-ALANINE AMIDASEDOMAIN-CONTAININGPROTEINSAOUHSC_02979 (Staphylococcusaureus) |
PF01832(Glucosaminidase)PF05257(CHAP) | 4 | ASN A 283PHE A 282ASN A 383ASP A 290 | None | 1.18A | 1zzqA-5t1qA:undetectable | 1zzqA-5t1qA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t4y | SUSC HOMOLOG (Bacteroidesthetaiotaomicron) |
no annotation | 4 | SER D 343ASN D 309GLN D 307ASN D 366 | None | 1.02A | 1zzqA-5t4yD:undetectable | 1zzqA-5t4yD:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgb | CRISPR-ASSOCIATEDENDONUCLEASE CAS9ANTI-CRISPR PROTEIN(ACRIIC1) (Neisseriameningitidis;Neisseriameningitidis) |
PF13395(HNH_4)no annotation | 4 | ASN A 88PHE A 87ASN A 13ASP B 44 | SO4 A 203 (-3.9A)NoneNoneNone | 1.12A | 1zzqA-5vgbA:undetectable | 1zzqA-5vgbA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3f | TUBULIN ALPHA-1CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 4 | SER A 224GLN A 15PHE A 225ASN A 227 | NoneNoneGTP A 502 (-3.8A)None | 1.05A | 1zzqA-5w3fA:undetectable | 1zzqA-5w3fA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w95 | CONSERVED MEMBRANEPROTEIN OFUNCHARACTERISEDFUNCTION (Mycobacteriumtuberculosis) |
no annotation | 4 | ASN A 132GLN A 139PHE A 130TRP A 84 | 1PE A 402 (-3.7A)None1PE A 402 (-3.5A)None | 1.35A | 1zzqA-5w95A:undetectable | 1zzqA-5w95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x2g | CRISPR-ASSOCIATEDENDONUCLEASE CAS9 (Campylobacterjejuni) |
no annotation | 4 | SER A 922ASN A 926ASN A 910ASP A 891 | None | 1.29A | 1zzqA-5x2gA:undetectable | 1zzqA-5x2gA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xb6 | UNCHARACTERIZEDPROTEIN YCJY (Escherichiacoli) |
no annotation | 4 | SER A 146ARG A 149ASN A 143ASP A 261 | None | 1.00A | 1zzqA-5xb6A:undetectable | 1zzqA-5xb6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjg | VACUOLAR PROTEIN 8NUCLEUS-VACUOLEJUNCTION PROTEIN 1 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00514(Arm)no annotation | 4 | SER A 280ARG A 242GLN B 308ASN B 304 | None | 0.86A | 1zzqA-5xjgA:undetectable | 1zzqA-5xjgA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xu1 | ABC TRANSPORTERPERMEAE (Streptococcuspneumoniae) |
no annotation | 4 | ARG M 240ASN M 56GLN M 54ASN M 242 | None | 1.14A | 1zzqA-5xu1M:undetectable | 1zzqA-5xu1M:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yh5 | NICKEL ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN (Staphylococcusaureus) |
no annotation | 4 | ASN A 450GLN A 130ASN A 310ASP A 308 | None | 1.15A | 1zzqA-5yh5A:undetectable | 1zzqA-5yh5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bo6 | - (-) |
no annotation | 4 | SER A 569ASN A 148GLN A 166ASP A 61 | None | 1.31A | 1zzqA-6bo6A:undetectable | 1zzqA-6bo6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dg4 | ULP1-LIKE SUMOPROTEASE (Chaetomiumthermophilum) |
no annotation | 4 | SER A 2GLN A 192PHE A 191ASP A 218 | None | 1.29A | 1zzqA-6dg4A:undetectable | 1zzqA-6dg4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoj | PROTEIN CFT1 (Saccharomycescerevisiae) |
no annotation | 4 | SER A 310ASN A 329GLN A 376PHE A 387 | None | 1.33A | 1zzqA-6eojA:undetectable | 1zzqA-6eojA:14.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eux | POLYMERASE BASICPROTEIN 2 (Influenza Bvirus) |
no annotation | 4 | GLN A 325PHE A 327ASN A 517ASP A 518 | BYB A 601 (-3.3A)BYB A 601 ( 4.4A)NoneNone | 1.33A | 1zzqA-6euxA:undetectable | 1zzqA-6euxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6evj | RNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Avirus) |
no annotation | 4 | SER B 345ARG B 316ASN B 314ASN B 346 | None | 1.31A | 1zzqA-6evjB:undetectable | 1zzqA-6evjB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0k | FE-S-CLUSTER-CONTAINING HYDROGENASEPOLYSULPHIDEREDUCTASE NRFDQUINOL:CYTOCHROME COXIDOREDUCTASEMONOHEME CYTOCHROMESUBUNIT (Rhodothermusmarinus;Rhodothermusmarinus;Rhodothermusmarinus) |
no annotationno annotationno annotation | 4 | ARG C 142PHE B 939ASN E 37ASP E 41 | NoneNoneHEC A 301 (-2.9A)None | 1.16A | 1zzqA-6f0kC:undetectable | 1zzqA-6f0kC:undetectable |