SIMILAR PATTERNS OF AMINO ACIDS FOR 1ZLQ_B_ACTB1503

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0g WINDBEUTEL PROTEIN

(Drosophila
melanogaster) 		PF07749
(ERp29)
PF07912
(ERp29_N) 		4 TYR A1160
GLN A1168
HIS A1202
ARG A1199
 None
 1.46A 1zlqB-2c0gA:
0.0		 1zlqB-2c0gA:
18.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 TYR A 382
GLN A 385
HIS A 395
ARG A 396
 None
ACT  A 508 (-2.9A)
ACT  A 508 (-3.9A)
None
 0.78A 1zlqB-3mzbA:
59.7		 1zlqB-3mzbA:
100.00