SIMILAR PATTERNS OF AMINO ACIDS FOR 1Z2B_C_VLBC800_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bou 4,5-DIOXYGENASE BETA
CHAIN


(Sphingomonas
paucimobilis)
PF02900
(LigB)
4 VAL B 152
ASN B  59
VAL B 244
ILE B 248
None
FE  B 501 (-3.2A)
None
None
0.98A 1z2bC-1bouB:
undetectable
1z2bC-1bouB:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cc1 HYDROGENASE (LARGE
SUBUNIT)


(Desulfomicrobium
baculatum)
PF00374
(NiFeSe_Hases)
5 PRO L 479
VAL L 473
ASN L 481
VAL L  37
ILE L  14
None
1.49A 1z2bC-1cc1L:
undetectable
1z2bC-1cc1L:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8r L-AMINO ACID OXIDASE

(Calloselasma
rhodostoma)
PF01593
(Amino_oxidase)
4 VAL A 480
ASN A 481
VAL A  36
ILE A 291
None
0.96A 1z2bC-1f8rA:
undetectable
1z2bC-1f8rA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0w GLUTATHIONE
SYNTHETASE


(Saccharomyces
cerevisiae)
PF03199
(GSH_synthase)
PF03917
(GSH_synth_ATP)
4 VAL A  18
ASN A  19
VAL A  46
ILE A  48
None
0.65A 1z2bC-1m0wA:
undetectable
1z2bC-1m0wA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mld MALATE DEHYDROGENASE

(Sus scrofa)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 PRO A 183
VAL A 170
VAL A 157
ILE A 206
None
1.09A 1z2bC-1mldA:
5.7
1z2bC-1mldA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogo DEXTRANASE

(Talaromyces
minioluteus)
PF03718
(Glyco_hydro_49)
PF17433
(Glyco_hydro_49N)
4 PRO X 132
VAL X 133
VAL X 483
ILE X 441
None
1.01A 1z2bC-1ogoX:
undetectable
1z2bC-1ogoX:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE


(Escherichia
coli)
PF01467
(CTP_transf_like)
4 VAL A  32
ASN A  64
VAL A  22
ILE A  87
None
1.05A 1z2bC-1qjcA:
undetectable
1z2bC-1qjcA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rgy BETA-LACTAMASE

(Citrobacter
freundii)
PF00144
(Beta-lactamase)
4 VAL A  12
ASN A  13
VAL A  30
ILE A  32
None
1.05A 1z2bC-1rgyA:
undetectable
1z2bC-1rgyA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smk MALATE
DEHYDROGENASE,
GLYOXYSOMAL


(Citrullus
lanatus)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 PRO A 227
VAL A 214
VAL A 201
ILE A 250
None
0.97A 1z2bC-1smkA:
2.5
1z2bC-1smkA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6z HYPOTHETICAL PROTEIN
TTHA0657


(Thermus
thermophilus)
PF04452
(Methyltrans_RNA)
4 PRO A 102
VAL A  77
VAL A  88
ILE A 100
None
0.93A 1z2bC-1v6zA:
undetectable
1z2bC-1v6zA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1


(Rattus
norvegicus)
PF00782
(DSPc)
4 PRO A 112
VAL A 115
VAL A  12
ILE A  21
None
0.79A 1z2bC-1zclA:
undetectable
1z2bC-1zclA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvo PUTATIVE
SEMIALDEHYDE
DEHYDROGENASE


(Oryza sativa)
PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC)
4 VAL A 139
ASN A 138
VAL A 102
ILE A  75
None
0.93A 1z2bC-2cvoA:
4.1
1z2bC-2cvoA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dc4 165AA LONG
HYPOTHETICAL PROTEIN


(Pyrococcus
horikoshii)
PF01928
(CYTH)
4 VAL A 110
ASN A 109
VAL A 143
ILE A 140
None
1.05A 1z2bC-2dc4A:
undetectable
1z2bC-2dc4A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3d UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE


(Escherichia
coli)
PF00483
(NTP_transferase)
4 VAL A  46
ASN A  47
VAL A 102
ILE A 104
None
1.07A 1z2bC-2e3dA:
undetectable
1z2bC-2e3dA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f3o PYRUVATE
FORMATE-LYASE 2


(Archaeoglobus
fulgidus)
PF01228
(Gly_radical)
PF02901
(PFL-like)
4 VAL A 446
ASN A 445
VAL A 548
ILE A 545
None
0.95A 1z2bC-2f3oA:
undetectable
1z2bC-2f3oA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hf8 PROBABLE HYDROGENASE
NICKEL INCORPORATION
PROTEIN HYPB


(Methanocaldococcus
jannaschii)
PF02492
(cobW)
4 VAL A 165
ASN A 167
VAL A 209
ILE A 139
None
GSP  A 300 (-3.2A)
None
None
1.07A 1z2bC-2hf8A:
undetectable
1z2bC-2hf8A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mki CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 4


(Homo sapiens)
PF16367
(RRM_7)
4 PRO A 153
VAL A  67
VAL A 121
ILE A 125
None
1.05A 1z2bC-2mkiA:
undetectable
1z2bC-2mkiA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nxf PUTATIVE DIMETAL
PHOSPHATASE


(Danio rerio)
PF00149
(Metallophos)
4 PRO A 184
VAL A 195
ASN A 175
ILE A 239
None
1.10A 1z2bC-2nxfA:
undetectable
1z2bC-2nxfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o0i C PROTEIN
ALPHA-ANTIGEN


(Streptococcus
agalactiae)
PF08829
(AlphaC_N)
PF17480
(AlphaC_C)
4 VAL 1 216
ASN 1 217
VAL 1 171
ILE 1 168
None
1.05A 1z2bC-2o0i1:
undetectable
1z2bC-2o0i1:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwz MALATE DEHYDROGENASE

(Escherichia
coli)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 PRO A 184
VAL A 171
VAL A 158
ILE A 206
None
1.05A 1z2bC-2pwzA:
5.7
1z2bC-2pwzA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4x SEED MATURATION
PROTEIN PM36 HOMOLOG


(Arabidopsis
thaliana)
PF03070
(TENA_THI-4)
4 PRO A 158
VAL A 159
VAL A  28
ILE A  30
None
0.83A 1z2bC-2q4xA:
undetectable
1z2bC-2q4xA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rem DISULFIDE
OXIDOREDUCTASE


(Xylella
fastidiosa)
PF13462
(Thioredoxin_4)
4 PRO A 154
VAL A 152
VAL A 161
ILE A  33
None
1.08A 1z2bC-2remA:
undetectable
1z2bC-2remA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vfw SHORT-CHAIN
Z-ISOPRENYL
DIPHOSPHATE
SYNTHETASE


(Mycobacterium
tuberculosis)
PF01255
(Prenyltransf)
4 VAL A 154
ASN A 153
VAL A 141
ILE A 111
None
0.86A 1z2bC-2vfwA:
undetectable
1z2bC-2vfwA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vun ENAMIDASE

(Eubacterium
barkeri)
PF01979
(Amidohydro_1)
4 PRO A 130
VAL A 135
VAL A  70
ILE A  85
None
1.11A 1z2bC-2vunA:
2.3
1z2bC-2vunA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5w KINESIN HEAVY CHAIN

(Drosophila
melanogaster)
PF00225
(Kinesin)
4 PRO A 116
VAL A 119
ASN A 120
VAL A 186
None
1.05A 1z2bC-2y5wA:
undetectable
1z2bC-2y5wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3adr PUTATIVE
UNCHARACTERIZED
PROTEIN ST1585


(Sulfurisphaera
tokodaii)
PF00753
(Lactamase_B)
4 PRO A  13
VAL A  38
ASN A  40
ILE A  19
None
1.06A 1z2bC-3adrA:
undetectable
1z2bC-3adrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ax1 SERRATE RNA EFFECTOR
MOLECULE


(Arabidopsis
thaliana)
PF04959
(ARS2)
PF12066
(DUF3546)
4 VAL A 363
ASN A 362
VAL A 386
ILE A 388
None
1.01A 1z2bC-3ax1A:
undetectable
1z2bC-3ax1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b4w ALDEHYDE
DEHYDROGENASE


(Mycobacterium
tuberculosis)
PF00171
(Aldedh)
4 PRO A 391
VAL A 281
VAL A 312
ILE A 327
None
1.06A 1z2bC-3b4wA:
undetectable
1z2bC-3b4wA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bex TYPE III
PANTOTHENATE KINASE


(Thermotoga
maritima)
PF03309
(Pan_kinase)
4 PRO A 170
VAL A 188
ASN A 189
ILE A 220
None
0.97A 1z2bC-3bexA:
undetectable
1z2bC-3bexA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE


(Listeria
innocua)
PF06838
(Met_gamma_lyase)
4 PRO A 212
VAL A 215
VAL A 185
ILE A 181
None
PEG  A 428 (-4.4A)
None
None
1.04A 1z2bC-3fd0A:
undetectable
1z2bC-3fd0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fw6 CELLULASE

(uncultured
bacterium)
PF12891
(Glyco_hydro_44)
4 VAL A 467
ASN A 486
VAL A  35
ILE A  37
None
0.90A 1z2bC-3fw6A:
undetectable
1z2bC-3fw6A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE


(Sulfolobus
solfataricus)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
4 VAL A 140
ASN A 141
VAL A  71
ILE A  69
None
1.05A 1z2bC-3gbrA:
2.6
1z2bC-3gbrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gem SHORT CHAIN
DEHYDROGENASE


(Pseudomonas
savastanoi)
PF13561
(adh_short_C2)
4 PRO A 177
VAL A 229
VAL A 208
ILE A 175
None
1.07A 1z2bC-3gemA:
6.8
1z2bC-3gemA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2u RAVER-1

(Homo sapiens)
PF00076
(RRM_1)
4 VAL B  75
ASN B  72
VAL B  98
ILE B  63
None
1.06A 1z2bC-3h2uB:
undetectable
1z2bC-3h2uB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hcy PUTATIVE
TWO-COMPONENT SENSOR
HISTIDINE KINASE
PROTEIN


(Sinorhizobium
meliloti)
PF13185
(GAF_2)
4 VAL A  69
ASN A  68
VAL A  83
ILE A  87
None
0.92A 1z2bC-3hcyA:
undetectable
1z2bC-3hcyA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hko CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 2
CALMODULIN-LIKE EF
HANDS


(Cryptosporidium
parvum)
PF00069
(Pkinase)
4 PRO A 220
VAL A 223
VAL A 270
ILE A 267
None
1.11A 1z2bC-3hkoA:
undetectable
1z2bC-3hkoA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ift GLYCINE CLEAVAGE
SYSTEM H PROTEIN


(Mycobacterium
tuberculosis)
PF01597
(GCV_H)
4 PRO A  89
VAL A  92
ASN A  93
VAL A  61
None
0.85A 1z2bC-3iftA:
undetectable
1z2bC-3iftA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv3 TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2


(Streptococcus
mutans)
PF01791
(DeoC)
4 PRO A 209
VAL A 187
ASN A 188
VAL A 206
None
1.03A 1z2bC-3iv3A:
undetectable
1z2bC-3iv3A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrk TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2


(Streptococcus
pyogenes)
PF01791
(DeoC)
4 PRO A 205
VAL A 183
ASN A 184
VAL A 202
None
1.05A 1z2bC-3jrkA:
undetectable
1z2bC-3jrkA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8p DSL1

(Kluyveromyces
lactis)
PF11989
(Dsl1_C)
4 VAL C 522
ASN C 523
VAL C 578
ILE C 573
None
1.04A 1z2bC-3k8pC:
undetectable
1z2bC-3k8pC:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kao TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE


(Staphylococcus
aureus)
PF01791
(DeoC)
4 PRO A 209
VAL A 187
ASN A 188
VAL A 206
None
1.03A 1z2bC-3kaoA:
undetectable
1z2bC-3kaoA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kve L-AMINO ACID OXIDASE

(Vipera
ammodytes)
PF01593
(Amino_oxidase)
4 VAL A 480
ASN A 481
VAL A  36
ILE A 291
None
0.88A 1z2bC-3kveA:
undetectable
1z2bC-3kveA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mxu GLYCINE CLEAVAGE
SYSTEM H PROTEIN


(Bartonella
henselae)
PF01597
(GCV_H)
4 PRO A  84
VAL A  87
ASN A  88
VAL A  56
None
0.94A 1z2bC-3mxuA:
undetectable
1z2bC-3mxuA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3my7 ALCOHOL
DEHYDROGENASE/ACETAL
DEHYDE DEHYDROGENASE


(Vibrio
parahaemolyticus)
PF00171
(Aldedh)
4 VAL A 434
ASN A 433
VAL A 212
ILE A 210
None
1.09A 1z2bC-3my7A:
undetectable
1z2bC-3my7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1


(Streptococcus
pyogenes)
PF01791
(DeoC)
4 PRO A 208
VAL A 186
ASN A 187
VAL A 205
None
1.03A 1z2bC-3myoA:
undetectable
1z2bC-3myoA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwn KINESIN-LIKE PROTEIN
KIF9


(Homo sapiens)
PF00225
(Kinesin)
4 VAL A 314
ASN A 316
VAL A  69
ILE A 115
None
1.06A 1z2bC-3nwnA:
undetectable
1z2bC-3nwnA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oam 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE


(Vibrio cholerae)
PF02348
(CTP_transf_3)
4 VAL A   6
ASN A  96
VAL A  82
ILE A  88
None
1.08A 1z2bC-3oamA:
undetectable
1z2bC-3oamA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pv2 DEGQ

(Legionella
fallonii)
PF13180
(PDZ_2)
PF13365
(Trypsin_2)
4 VAL A  85
ASN A  82
VAL A  23
ILE A  66
None
1.02A 1z2bC-3pv2A:
undetectable
1z2bC-3pv2A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pv4 DEGQ

(Legionella
fallonii)
PF13180
(PDZ_2)
PF13365
(Trypsin_2)
4 VAL A  85
ASN A  82
VAL A  23
ILE A  66
None
0.98A 1z2bC-3pv4A:
undetectable
1z2bC-3pv4A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxx CARVEOL
DEHYDROGENASE


(Mycobacterium
avium)
PF13561
(adh_short_C2)
4 PRO A 204
VAL A 275
VAL A 248
ILE A 253
NAD  A 284 (-4.0A)
None
None
None
1.10A 1z2bC-3pxxA:
6.5
1z2bC-3pxxA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9o EXOTOXIN A

(Vibrio cholerae)
PF09009
(Exotox-A_cataly)
PF09101
(Exotox-A_bind)
PF09102
(Exotox-A_target)
4 PRO A  85
VAL A  80
ASN A  81
VAL A  88
None
1.07A 1z2bC-3q9oA:
undetectable
1z2bC-3q9oA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdk RIBULOKINASE

(Bacillus
halodurans)
PF00370
(FGGY_N)
PF02782
(FGGY_C)
4 VAL A  92
ASN A 272
VAL A 191
ILE A  90
None
1.06A 1z2bC-3qdkA:
undetectable
1z2bC-3qdkA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjy ENDOGLUCANASE
FNCEL5A


(Fervidobacterium
nodosum)
PF00150
(Cellulase)
4 VAL A 277
ASN A 275
VAL A 223
ILE A 221
None
1.07A 1z2bC-3rjyA:
undetectable
1z2bC-3rjyA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rqb UNCHARACTERIZED
PROTEIN


(Alicyclobacillus
acidocaldarius)
PF13622
(4HBT_3)
4 PRO A 191
VAL A 193
VAL A 201
ILE A 203
None
1.01A 1z2bC-3rqbA:
undetectable
1z2bC-3rqbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uat DISKS LARGE HOMOLOG
1


(Rattus
norvegicus)
PF00625
(Guanylate_kin)
PF07653
(SH3_2)
4 VAL A 734
ASN A 735
VAL A 891
ILE A 837
None
0.99A 1z2bC-3uatA:
undetectable
1z2bC-3uatA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zkb DNA GYRASE SUBUNIT B

(Mycobacterium
tuberculosis)
PF00204
(DNA_gyraseB)
PF02518
(HATPase_c)
4 VAL A 125
ASN A 129
VAL A 171
ILE A  84
ANP  A 601 (-3.8A)
None
None
ANP  A 601 (-4.3A)
0.96A 1z2bC-3zkbA:
undetectable
1z2bC-3zkbA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zy3 PUTATIVE GDP-FUCOSE
PROTEIN
O-FUCOSYLTRANSFERASE
1


(Caenorhabditis
elegans)
PF10250
(O-FucT)
4 VAL A 354
ASN A 352
VAL A 248
ILE A 252
None
0.76A 1z2bC-3zy3A:
undetectable
1z2bC-3zy3A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag6 TYPE IV SECRETORY
PATHWAY VIRB4
COMPONENTS-LIKE
PROTEIN


(Thermoanaerobacter
pseudethanolicus)
PF01935
(DUF87)
4 VAL A 450
ASN A 449
VAL A 432
ILE A 289
None
1.05A 1z2bC-4ag6A:
undetectable
1z2bC-4ag6A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d48 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE


(Erwinia
amylovora)
PF00483
(NTP_transferase)
4 VAL A  46
ASN A  47
VAL A 102
ILE A 104
None
1.05A 1z2bC-4d48A:
undetectable
1z2bC-4d48A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d73 1-CYS PEROXIREDOXIN

(Plasmodium
falciparum)
PF08534
(Redoxin)
4 VAL B 231
ASN B 230
VAL B 197
ILE B 199
None
0.99A 1z2bC-4d73B:
undetectable
1z2bC-4d73B:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eq9 ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN-AMINO ACID
TRANSPORT


(Streptococcus
pneumoniae)
PF00497
(SBP_bac_3)
4 PRO A 230
VAL A 102
VAL A  67
ILE A 121
None
0.94A 1z2bC-4eq9A:
undetectable
1z2bC-4eq9A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ffl PYLC

(Methanosarcina
barkeri)
PF02655
(ATP-grasp_3)
4 PRO A  69
VAL A   7
ASN A  71
VAL A  50
None
None
ATP  A 908 (-4.1A)
ATP  A 908 (-3.7A)
1.05A 1z2bC-4fflA:
undetectable
1z2bC-4fflA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj6 GLYCOSIDE HYDROLASE
FAMILY 33, CANDIDATE
SIALIDASE


(Parabacteroides
distasonis)
PF13859
(BNR_3)
PF14873
(BNR_assoc_N)
4 PRO A 269
VAL A 282
VAL A 234
ILE A 232
None
1.09A 1z2bC-4fj6A:
undetectable
1z2bC-4fj6A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ivi CARBOXYLESTERASE

(uncultured
bacterium)
PF00144
(Beta-lactamase)
4 VAL A 135
ASN A 134
VAL A 154
ILE A 158
None
1.07A 1z2bC-4iviA:
undetectable
1z2bC-4iviA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iwh 3-ISOPROPYLMALATE
DEHYDROGENASE


(Burkholderia
thailandensis)
PF00180
(Iso_dh)
4 PRO A  13
VAL A  16
ASN A  17
VAL A   5
None
0.71A 1z2bC-4iwhA:
undetectable
1z2bC-4iwhA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k28 SHIKIMATE
DEHYDROGENASE FAMILY
PROTEIN


(Pseudomonas
putida)
PF00899
(ThiF)
PF08501
(Shikimate_dh_N)
4 PRO A  22
ASN A  26
VAL A   9
ILE A  11
None
0.93A 1z2bC-4k28A:
undetectable
1z2bC-4k28A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kbm RNA
POLYMERASE-BINDING
TRANSCRIPTION FACTOR
CARD


(Mycobacterium
tuberculosis)
PF02559
(CarD_CdnL_TRCF)
4 VAL B 101
ASN B 102
VAL B  62
ILE B   2
None
0.95A 1z2bC-4kbmB:
undetectable
1z2bC-4kbmB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kkm POLYPRENYL
SYNTHETASE


(Zymomonas
mobilis)
PF00348
(polyprenyl_synt)
4 PRO A  51
VAL A  54
VAL A  71
ILE A  75
None
0.97A 1z2bC-4kkmA:
undetectable
1z2bC-4kkmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m75 U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM6


(Saccharomyces
cerevisiae)
PF01423
(LSM)
4 VAL D  47
ASN D  46
VAL D  78
ILE D  81
None
1.07A 1z2bC-4m75D:
undetectable
1z2bC-4m75D:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qyi HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE


(Bacillus
anthracis)
PF00156
(Pribosyltran)
4 VAL A  87
ASN A  88
VAL A  36
ILE A  38
None
0.93A 1z2bC-4qyiA:
3.5
1z2bC-4qyiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twb RIBOSE-PHOSPHATE
PYROPHOSPHOKINASE


(Sulfolobus
solfataricus)
PF00156
(Pribosyltran)
PF13793
(Pribosyltran_N)
4 PRO A  87
VAL A 124
VAL A 283
ILE A 287
None
0.97A 1z2bC-4twbA:
4.9
1z2bC-4twbA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u13 PUTATIVE POLYKETIDE
CYCLASE SMA1630


(Sinorhizobium
meliloti)
PF12680
(SnoaL_2)
4 PRO A   4
VAL A   7
ASN A   8
VAL A  74
None
1.09A 1z2bC-4u13A:
undetectable
1z2bC-4u13A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wen K88 FIMBRIAL PROTEIN
AC


(Escherichia
coli)
PF02432
(Fimbrial_K88)
4 VAL A 257
ASN A 256
VAL A  29
ILE A  60
None
0.85A 1z2bC-4wenA:
undetectable
1z2bC-4wenA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xdo LYSINE-SPECIFIC
DEMETHYLASE 4C


(Homo sapiens)
PF02373
(JmjC)
PF02375
(JmjN)
4 VAL A 173
ASN A 292
VAL A 315
ILE A 317
None
1.02A 1z2bC-4xdoA:
undetectable
1z2bC-4xdoA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xzk PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS


(Vibrio
splendidus)
PF03496
(ADPrib_exo_Tox)
4 PRO A 138
VAL A 136
ASN A 197
VAL A 238
None
1.11A 1z2bC-4xzkA:
undetectable
1z2bC-4xzkA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah5 LEUCINE--TRNA LIGASE

(Agrobacterium
tumefaciens)
PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2)
4 PRO A 583
VAL A 586
VAL A 595
ILE A  48
None
0.97A 1z2bC-5ah5A:
undetectable
1z2bC-5ah5A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bx1 PROTEIN TYROSINE
PHOSPHATASE TYPE IVA
1


(Homo sapiens)
PF00782
(DSPc)
4 PRO A 112
VAL A 115
VAL A  12
ILE A  21
SO4  A 202 (-4.5A)
None
None
None
0.97A 1z2bC-5bx1A:
undetectable
1z2bC-5bx1A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bxy RNA
METHYLTRANSFERASE


(Salinibacter
ruber)
PF13847
(Methyltransf_31)
4 PRO A  99
VAL A 101
ASN A 102
VAL A   2
None
None
None
SAH  A 201 (-4.2A)
1.03A 1z2bC-5bxyA:
2.5
1z2bC-5bxyA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzt CYLM

(Enterococcus
faecalis)
PF05147
(LANC_like)
PF13575
(DUF4135)
4 PRO A 749
VAL A 752
VAL A 706
ILE A 703
None
1.05A 1z2bC-5dztA:
undetectable
1z2bC-5dztA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzz DESMOPLAKIN

(Homo sapiens)
PF00681
(Plectin)
4 PRO A2230
VAL A2233
ASN A2234
VAL A2219
None
1.04A 1z2bC-5dzzA:
undetectable
1z2bC-5dzzA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f0k VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 35


(Homo sapiens)
PF03635
(Vps35)
4 VAL A 440
ASN A 443
VAL A 415
ILE A 460
None
1.08A 1z2bC-5f0kA:
undetectable
1z2bC-5f0kA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gk9 BRD1 PROTEIN
HISTONE
ACETYLTRANSFERASE
KAT7


(Homo sapiens)
PF01853
(MOZ_SAS)
no annotation
4 PRO A 552
VAL A 556
VAL B  40
ILE B  53
None
1.03A 1z2bC-5gk9A:
undetectable
1z2bC-5gk9A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hjl TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE


(Streptococcus
porcinus)
PF01791
(DeoC)
4 PRO A 208
VAL A 186
ASN A 187
VAL A 205
None
1.06A 1z2bC-5hjlA:
undetectable
1z2bC-5hjlA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S15


(Pyrococcus
abyssi)
PF00312
(Ribosomal_S15)
PF08069
(Ribosomal_S13_N)
4 VAL Q 103
ASN Q 104
VAL Q 157
ILE Q  99
None
1.02A 1z2bC-5jb3Q:
undetectable
1z2bC-5jb3Q:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksw DIHYDROOROTATE
DEHYDROGENASE


(Lactococcus
lactis)
PF01180
(DHO_dh)
4 PRO A  22
VAL A 269
VAL A 279
ILE A  20
None
1.07A 1z2bC-5kswA:
undetectable
1z2bC-5kswA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m2o PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN


(Ruminococcus
flavefaciens)
PF00963
(Cohesin)
4 VAL A  99
ASN A 100
VAL A  45
ILE A 138
None
1.01A 1z2bC-5m2oA:
undetectable
1z2bC-5m2oA:
16.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5nd4 TUBULIN ALPHA CHAIN

(Bos taurus)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
4 PRO A 325
VAL A 328
VAL A 353
ILE A 355
None
0.69A 1z2bC-5nd4A:
55.9
1z2bC-5nd4A:
92.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ny5 3,4-DIHYDROXYBENZOAT
E DECARBOXYLASE


(Enterobacter
cloacae)
PF01977
(UbiD)
4 PRO A 138
ASN A 140
VAL A  73
ILE A  71
None
1.05A 1z2bC-5ny5A:
undetectable
1z2bC-5ny5A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ucd NAD(P)-DEPENDENT
BENZALDEHYDE
DEHYDROGENASE


(Pseudomonas
putida)
PF00171
(Aldedh)
4 VAL A 358
ASN A 359
VAL A 368
ILE A 223
None
0.80A 1z2bC-5ucdA:
undetectable
1z2bC-5ucdA:
20.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ucy TUBULIN ALPHA CHAIN

(Tetrahymena
thermophila)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
4 PRO A 325
VAL A 328
ASN A 329
ILE A 355
None
0.92A 1z2bC-5ucyA:
51.9
1z2bC-5ucyA:
86.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ucy TUBULIN ALPHA CHAIN

(Tetrahymena
thermophila)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
4 PRO A 325
VAL A 328
ASN A 329
VAL A 353
None
1.01A 1z2bC-5ucyA:
51.9
1z2bC-5ucyA:
86.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vm2 ALCOHOL
DEHYDROGENASE


(Escherichia
coli)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 PRO A 255
VAL A 258
VAL A 285
ILE A 264
None
1.06A 1z2bC-5vm2A:
4.1
1z2bC-5vm2A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vrb TRANSKETOLASE

(Neisseria
gonorrhoeae)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
4 VAL A 651
ASN A 650
VAL A 607
ILE A 605
None
0.87A 1z2bC-5vrbA:
undetectable
1z2bC-5vrbA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wi5 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE 1


(Streptococcus
pneumoniae)
PF00275
(EPSP_synthase)
4 VAL A  52
ASN A  56
VAL A  46
ILE A  48
None
0.94A 1z2bC-5wi5A:
undetectable
1z2bC-5wi5A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ao8 ARGININE--TRNA
LIGASE


(Neisseria
gonorrhoeae)
PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1)
4 PRO A 512
VAL A 506
VAL A 145
ILE A 142
None
1.03A 1z2bC-6ao8A:
undetectable
1z2bC-6ao8A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aoo MALATE DEHYDROGENASE

(Haemophilus
influenzae)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 PRO A 184
VAL A 171
VAL A 158
ILE A 206
None
1.10A 1z2bC-6aooA:
5.7
1z2bC-6aooA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bzg SPORULATION-SPECIFIC
PROTEIN 16


(Saccharomyces
cerevisiae)
no annotation 4 VAL A  62
ASN A  61
VAL A  28
ILE A  11
None
0.94A 1z2bC-6bzgA:
undetectable
1z2bC-6bzgA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c26 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT STT3


(Saccharomyces
cerevisiae)
no annotation 4 VAL A 116
ASN A 113
VAL A  36
ILE A  42
None
EGY  A 801 (-3.3A)
None
None
1.08A 1z2bC-6c26A:
undetectable
1z2bC-6c26A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ehs HYDROGENASE-2 LARGE
CHAIN


(Escherichia
coli)
no annotation 4 PRO L 533
VAL L 527
VAL L  28
ILE L   5
None
1.09A 1z2bC-6ehsL:
undetectable
1z2bC-6ehsL:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g0c UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA


(Legionella
pneumophila)
no annotation 4 VAL A 380
ASN A 381
VAL A 362
ILE A 370
None
0.89A 1z2bC-6g0cA:
undetectable
1z2bC-6g0cA:
10.80