SIMILAR PATTERNS OF AMINO ACIDS FOR 1Z11_C_8MOC501_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7j | PHOSPHORIBULOKINASE (Rhodobactersphaeroides) |
PF00485(PRK) | 5 | PHE A 25VAL A 21ILE A 152GLY A 153LEU A 268 | None | 0.77A | 1z11C-1a7jA:0.0 | 1z11C-1a7jA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ao0 | GLUTAMINEPHOSPHORIBOSYLPYROPHOSPHATEAMIDOTRANSFERASE (Bacillussubtilis) |
PF00156(Pribosyltran)PF13522(GATase_6) | 5 | ILE A 395GLY A 351ILE A 373LEU A 413PHE A 415 | None5GP A 467 (-3.2A)NoneNoneNone | 0.97A | 1z11C-1ao0A:0.0 | 1z11C-1ao0A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1exf | EXFOLIATVE TOXIN A (Staphylococcusaureus) |
PF13365(Trypsin_2) | 5 | PHE A 200ILE A 139GLY A 140THR A 43ILE A 212 | None | 1.12A | 1z11C-1exfA:undetectable | 1z11C-1exfA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gg3 | ERYTHROID MEMBRANEPROTEIN 4.1R (Homo sapiens) |
PF00373(FERM_M)PF09379(FERM_N)PF09380(FERM_C) | 5 | PHE A 223ILE A 254GLY A 255ILE A 202LEU A 204 | None | 0.99A | 1z11C-1gg3A:0.0 | 1z11C-1gg3A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jsc | ACETOHYDROXY-ACIDSYNTHASE (Saccharomycescerevisiae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ASN A 99GLY A 95THR A 254ILE A 118LEU A 160 | None | 1.09A | 1z11C-1jscA:0.0 | 1z11C-1jscA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k72 | ENDOGLUCANASE 9G ([Clostridium]cellulolyticum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 5 | PHE A 566ASN A 466GLY A 464ILE A 461PHE A 495 | None | 1.12A | 1z11C-1k72A:undetectable | 1z11C-1k72A:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lth | L-LACTATEDEHYDROGENASE (T-AND R- STATETETRAMER COMPLEX) (Bifidobacteriumlongum) |
no annotation | 5 | VAL T 80ILE T 247GLY T 244ILE T 31LEU T 10 | None | 0.90A | 1z11C-1lthT:0.0 | 1z11C-1lthT:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pv9 | XAA-PRO DIPEPTIDASE (Pyrococcusfuriosus) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 5 | VAL A 164ILE A 148THR A 343ILE A 221LEU A 210 | None | 1.10A | 1z11C-1pv9A:0.0 | 1z11C-1pv9A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rlm | PHOSPHATASE (Escherichiacoli) |
PF08282(Hydrolase_3) | 5 | PHE A 149PHE A 104ILE A 93GLY A 94ILE A 172 | None | 1.07A | 1z11C-1rlmA:0.0 | 1z11C-1rlmA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rro | RAT ONCOMODULIN (Rattus rattus) |
PF13499(EF-hand_7) | 5 | PHE A 29VAL A 106GLY A 34ILE A 2PHE A 70 | None | 1.05A | 1z11C-1rroA:undetectable | 1z11C-1rroA:12.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t47 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Streptomycesavermitilis) |
PF00903(Glyoxalase) | 5 | PHE A 242PHE A 210ILE A 105GLY A 22ILE A 185 | None | 1.07A | 1z11C-1t47A:undetectable | 1z11C-1t47A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wcz | GLUTAMYLENDOPEPTIDASE (Staphylococcusaureus) |
PF13365(Trypsin_2) | 5 | VAL A 52GLY A 38THR A 23LEU A 63PHE A 99 | None | 1.07A | 1z11C-1wczA:undetectable | 1z11C-1wczA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wmj | THIOREDOXIN H-TYPE (Oryza sativa) |
PF00085(Thioredoxin) | 5 | PHE A 87VAL A 97ILE A 109ILE A 46PHE A 50 | None | 1.12A | 1z11C-1wmjA:undetectable | 1z11C-1wmjA:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wy2 | XAA-PRO DIPEPTIDASE (Pyrococcushorikoshii) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 5 | VAL A 167ILE A 151THR A 346ILE A 224LEU A 213 | None | 1.04A | 1z11C-1wy2A:undetectable | 1z11C-1wy2A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xg2 | PECTINESTERASE 1 (Solanumlycopersicum) |
PF01095(Pectinesterase) | 5 | VAL A 309ASN A 123ILE A 122ILE A 298LEU A 304 | None | 0.97A | 1z11C-1xg2A:undetectable | 1z11C-1xg2A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yy3 | S-ADENOSYLMETHIONINE:TRNARIBOSYLTRANSFERASE-ISOMERASE (Bacillussubtilis) |
PF02547(Queuosine_synth) | 5 | VAL A 197ILE A 47ILE A 295LEU A 56PHE A 184 | None | 0.86A | 1z11C-1yy3A:undetectable | 1z11C-1yy3A:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aja | ANKYRIN REPEATFAMILY PROTEIN (Legionellapneumophila) |
no annotation | 5 | ASN A 284GLY A 236ILE A 215LEU A 219PHE A 202 | None | 1.08A | 1z11C-2ajaA:undetectable | 1z11C-2ajaA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3r | LECTIN ALPHA CHAIN (Cratyliaargentea) |
PF00139(Lectin_legB) | 5 | VAL A 79ILE A 27ILE A 213LEU A 81PHE A 190 | None | 1.12A | 1z11C-2d3rA:undetectable | 1z11C-2d3rA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fco | RECOMBINATIONPROTEIN U(PENICILLIN-BINDINGPROTEIN RELATEDFACTOR A) (Geobacilluskaustophilus) |
PF03838(RecU) | 5 | PHE A 98VAL A 193ILE A 52THR A 40ILE A 187 | None | 1.08A | 1z11C-2fcoA:undetectable | 1z11C-2fcoA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k78 | IRON-REGULATEDSURFACE DETERMINANTPROTEIN C (Staphylococcusaureus) |
PF05031(NEAT) | 5 | PHE A 53VAL A 72ILE A 117GLY A 80PHE A 104 | ZNH A 151 (-3.6A)NoneZNH A 151 (-4.0A)NoneNone | 1.04A | 1z11C-2k78A:undetectable | 1z11C-2k78A:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n0s | FE-HYDROGENASE (Chlamydomonasreinhardtii) |
PF02256(Fe_hyd_SSU)PF02906(Fe_hyd_lg_C) | 5 | PHE A 84ILE A 212THR A 214ILE A 59LEU A 75 | None | 0.98A | 1z11C-2n0sA:undetectable | 1z11C-2n0sA:20.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pg6 | CYTOCHROME P450 2A6 (Homo sapiens) |
PF00067(p450) | 9 | PHE A 107PHE A 111VAL A 117ILE A 300GLY A 301THR A 305ILE A 366LEU A 370PHE A 480 | NoneNoneHEM A 500 (-3.7A)NoneHEM A 500 ( 4.7A)HEM A 500 (-3.6A)HEM A 500 ( 4.1A)HEM A 500 ( 3.8A)None | 0.36A | 1z11C-2pg6A:64.7 | 1z11C-2pg6A:99.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vn8 | RETICULON-4-INTERACTING PROTEIN 1 (Homo sapiens) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 5 | PHE A 372VAL A 375GLY A 120ILE A 48LEU A 57 | None | 1.02A | 1z11C-2vn8A:undetectable | 1z11C-2vn8A:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9y | FATTY ACID/RETINOLBINDING PROTEINPROTEIN 7, ISOFORMA, CONFIRMED BYTRANSCRIPT EVIDENCE (Caenorhabditiselegans) |
PF05823(Gp-FAR-1) | 5 | VAL A 53THR A 101ILE A 25LEU A 60PHE A 21 | None | 0.96A | 1z11C-2w9yA:undetectable | 1z11C-2w9yA:13.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zwi | ALPHA-/BETA-GALACTOSIDEALPHA-2,3-SIALYLTRANSFERASE (Photobacteriumphosphoreum) |
PF11477(PM0188) | 5 | ILE A 276GLY A 277ILE A 291LEU A 292PHE A 373 | C5P A 1 (-4.0A)C5P A 1 (-4.0A)NoneNoneNone | 1.11A | 1z11C-2zwiA:undetectable | 1z11C-2zwiA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c2g | SYS-1 PROTEIN (Caenorhabditiselegans) |
no annotation | 5 | VAL A 460ILE A 468GLY A 466LEU A 496PHE A 527 | None | 1.05A | 1z11C-3c2gA:undetectable | 1z11C-3c2gA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3x | BIPA (Vibrioparahaemolyticus) |
PF00679(EFG_C) | 5 | PHE A 179PHE A 175ASN A 142ILE A 139GLY A 138 | None | 1.00A | 1z11C-3e3xA:undetectable | 1z11C-3e3xA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ed4 | ARYLSULFATASE (Escherichiacoli) |
PF00884(Sulfatase) | 5 | VAL A 241ASN A 288THR A 68LEU A 53PHE A 316 | None | 1.01A | 1z11C-3ed4A:undetectable | 1z11C-3ed4A:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3epj | TRNAISOPENTENYLTRANSFERASE (Saccharomycescerevisiae) |
PF01715(IPPT) | 5 | VAL A 221ILE A 258ILE A 233LEU A 225PHE A 263 | None A E 37 ( 3.9A)NoneNoneNone | 1.09A | 1z11C-3epjA:undetectable | 1z11C-3epjA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ghy | KETOPANTOATEREDUCTASE PROTEIN (Ralstoniasolanacearum) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | PHE A 109VAL A 294ILE A 249GLY A 246LEU A 205 | None | 1.11A | 1z11C-3ghyA:undetectable | 1z11C-3ghyA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4x | PROLIFERATING CELLNUCLEAR ANTIGEN (Saccharomycescerevisiae) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | ASN A 159ILE A 158ILE A 227LEU A 229PHE A 237 | None | 1.13A | 1z11C-3k4xA:undetectable | 1z11C-3k4xA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4x | PROLIFERATING CELLNUCLEAR ANTIGEN (Saccharomycescerevisiae) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | ASN A 426ILE A 425ILE A 494LEU A 496PHE A 504 | None | 1.13A | 1z11C-3k4xA:undetectable | 1z11C-3k4xA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kke | LACI FAMILYTRANSCRIPTIONALREGULATOR (Mycolicibacteriumsmegmatis) |
PF13377(Peripla_BP_3) | 5 | VAL A 276ILE A 167GLY A 166THR A 202ILE A 173 | None | 1.11A | 1z11C-3kkeA:undetectable | 1z11C-3kkeA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8k | DIHYDROLIPOYLDEHYDROGENASE (Sulfolobussolfataricus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | VAL A 215GLY A 179ILE A 226LEU A 219PHE A 228 | None | 1.11A | 1z11C-3l8kA:undetectable | 1z11C-3l8kA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8k | DIHYDROLIPOYLDEHYDROGENASE (Sulfolobussolfataricus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | VAL A 215ILE A 207ILE A 226LEU A 219PHE A 228 | None | 1.09A | 1z11C-3l8kA:undetectable | 1z11C-3l8kA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lca | PROTEIN TOM71 (Saccharomycescerevisiae) |
PF00515(TPR_1)PF13181(TPR_8)PF14559(TPR_19) | 5 | PHE A 273PHE A 276ASN A 379ILE A 353LEU A 302 | None | 0.97A | 1z11C-3lcaA:undetectable | 1z11C-3lcaA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lw2 | PLASMINOGENACTIVATOR INHIBITOR1 (Mus musculus) |
PF00079(Serpin) | 5 | PHE A 278ILE A 326ILE A 237LEU A 275PHE A 358 | None | 1.09A | 1z11C-3lw2A:undetectable | 1z11C-3lw2A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgx | PUTATIVE P450MONOOXYGENASE (Amycolatopsisbalhimycina) |
PF00067(p450) | 5 | VAL A 88ASN A 231ILE A 234GLY A 235THR A 239 | HEM A 397 ( 3.8A)GOL A 399 (-4.2A)GOL A 400 ( 4.0A)GOL A 399 ( 3.6A)HEM A 397 (-3.5A) | 0.91A | 1z11C-3mgxA:30.2 | 1z11C-3mgxA:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n23 | SODIUM/POTASSIUM-TRANSPORTING ATPASESUBUNIT BETA-1 (Sus scrofa) |
PF00287(Na_K-ATPase) | 5 | PHE B 186ASN B 282ILE B 283GLY B 280LEU B 240 | None | 0.88A | 1z11C-3n23B:undetectable | 1z11C-3n23B:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n9x | PHOSPHOTRANSFERASE (Plasmodiumberghei) |
PF00069(Pkinase) | 5 | PHE A 263ILE A 296GLY A 297ILE A 316LEU A 289 | None | 1.08A | 1z11C-3n9xA:undetectable | 1z11C-3n9xA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nie | MAP2 KINASE (Plasmodiumfalciparum) |
PF00069(Pkinase) | 5 | PHE A 268ILE A 301GLY A 302ILE A 321LEU A 294 | None | 1.10A | 1z11C-3nieA:undetectable | 1z11C-3nieA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzp | ARGININEDECARBOXYLASE (Campylobacterjejuni) |
PF02784(Orn_Arg_deC_N) | 5 | PHE A 444VAL A 336ILE A 462LEU A 511PHE A 513 | None | 1.04A | 1z11C-3nzpA:undetectable | 1z11C-3nzpA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3odt | PROTEIN DOA1 (Saccharomycescerevisiae) |
PF00400(WD40) | 5 | PHE A 193VAL A 146GLY A 191LEU A 164PHE A 174 | None | 0.98A | 1z11C-3odtA:undetectable | 1z11C-3odtA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p9c | CAFFEIC ACIDO-METHYLTRANSFERASE (Lolium perenne) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 5 | ILE A 349THR A 185ILE A 215LEU A 260PHE A 195 | NoneACT A 901 (-3.5A)NoneNoneNone | 1.12A | 1z11C-3p9cA:undetectable | 1z11C-3p9cA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pj0 | LMO0305 PROTEIN (Listeriamonocytogenes) |
PF01212(Beta_elim_lyase) | 5 | VAL A 333ILE A 317GLY A 316LEU A 269PHE A 351 | None | 1.12A | 1z11C-3pj0A:undetectable | 1z11C-3pj0A:23.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tov | GLYCOSYL TRANSFERASEFAMILY 9 (Veillonellaparvula) |
PF01075(Glyco_transf_9) | 5 | ASN A 260ILE A 185GLY A 186ILE A 241LEU A 178 | None | 1.11A | 1z11C-3tovA:undetectable | 1z11C-3tovA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3unn | MEDIATOR OF DNADAMAGE CHECKPOINTPROTEIN 1 (Homo sapiens) |
PF00498(FHA) | 5 | VAL A 64ILE A 71THR A 98ILE A 121LEU A 34 | None | 1.10A | 1z11C-3unnA:undetectable | 1z11C-3unnA:13.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgf | MALTO-OLIGOSYLTREHALOSE TREHALOHYDROLASE (Sulfolobussolfataricus) |
PF00128(Alpha-amylase)PF09071(Alpha-amyl_C) | 5 | VAL A 188ILE A 185GLY A 248ILE A 302LEU A 251 | None | 1.12A | 1z11C-3vgfA:undetectable | 1z11C-3vgfA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqo | UNCHARACTERIZEDPROTEIN MJ1311 (Methanocaldococcusjannaschii) |
PF01261(AP_endonuc_2) | 5 | VAL A 118ILE A 189GLY A 188ILE A 182LEU A 142 | None | 1.12A | 1z11C-3wqoA:undetectable | 1z11C-3wqoA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zif | PENTON PROTEIN (BovinemastadenovirusB) |
PF01686(Adeno_Penton_B) | 5 | PHE M 260PHE M 239ILE M 250GLY M 249THR M 337 | None | 1.12A | 1z11C-3zifM:undetectable | 1z11C-3zifM:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a05 | CELLOBIOHYDROLASEFAMILY 6 (Chaetomiumthermophilum) |
PF01341(Glyco_hydro_6) | 5 | ASN A 129ILE A 196GLY A 195THR A 245LEU A 164 | None | 1.00A | 1z11C-4a05A:undetectable | 1z11C-4a05A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4asl | EPA1P ([Candida]glabrata) |
PF10528(GLEYA) | 5 | PHE A 171VAL A 169ILE A 109LEU A 221PHE A 252 | None | 1.12A | 1z11C-4aslA:undetectable | 1z11C-4aslA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 5 | VAL V1202ILE V1180GLY V1182ILE V1263LEU V1250 | None | 0.96A | 1z11C-4bxsV:undetectable | 1z11C-4bxsV:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4by6 | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1 (Saccharomycescerevisiae) |
PF04054(Not1) | 5 | VAL A2065ILE A2074ILE A2052LEU A2059PHE A2048 | None | 1.10A | 1z11C-4by6A:undetectable | 1z11C-4by6A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c8q | DNA TOPOISOMERASE2-ASSOCIATED PROTEINPAT1 (Saccharomycescerevisiae) |
PF09770(PAT1) | 5 | PHE H 556ILE H 595ILE H 533LEU H 527PHE H 587 | None | 1.02A | 1z11C-4c8qH:undetectable | 1z11C-4c8qH:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cmr | GLYCOSYLHYDROLASE/DEACETYLASE FAMILY PROTEIN (Pyrococcus sp.ST04) |
no annotation | 5 | PHE A 362GLY A 463ILE A 468LEU A 497PHE A 366 | None | 1.14A | 1z11C-4cmrA:undetectable | 1z11C-4cmrA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dyo | ASPARTYLAMINOPEPTIDASE (Homo sapiens) |
PF02127(Peptidase_M18) | 5 | VAL A 429ILE A 91GLY A 92THR A 296LEU A 427 | None | 1.07A | 1z11C-4dyoA:undetectable | 1z11C-4dyoA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ei8 | PLASMID REPLICATIONPROTEIN REPX (Bacillus cereus) |
PF00091(Tubulin) | 5 | PHE A 94VAL A 89GLY A 22ILE A 74LEU A 76 | None | 0.97A | 1z11C-4ei8A:undetectable | 1z11C-4ei8A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eu2 | PROTEASOME COMPONENTC7-ALPHA (Saccharomycescerevisiae) |
PF00227(Proteasome)PF10584(Proteasome_A_N) | 5 | PHE A 186ILE A 194GLY A 47THR A 51ILE A 154 | None | 1.11A | 1z11C-4eu2A:undetectable | 1z11C-4eu2A:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eut | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | VAL A 280ILE A 207GLY A 208LEU A 277PHE A 112 | None | 0.95A | 1z11C-4eutA:undetectable | 1z11C-4eutA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4euu | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | VAL A 280ILE A 207GLY A 208LEU A 277PHE A 112 | None | 0.95A | 1z11C-4euuA:undetectable | 1z11C-4euuA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdw | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidesovatus) |
PF07523(Big_3)PF13306(LRR_5) | 5 | VAL A 151ASN A 170ILE A 138LEU A 135PHE A 159 | None | 0.89A | 1z11C-4fdwA:undetectable | 1z11C-4fdwA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gf8 | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio cholerae) |
PF00496(SBP_bac_5) | 5 | VAL A 404ILE A 480ILE A 381LEU A 354PHE A 268 | None | 1.13A | 1z11C-4gf8A:undetectable | 1z11C-4gf8A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4grc | PUTATIVE MEMBRANEPROTEIN (Streptomycescoelicolor) |
PF04261(Dyp_perox) | 5 | PHE A 363VAL A 274GLY A 373LEU A 165PHE A 168 | HEM A 502 (-3.9A)NoneNoneNoneNone | 0.83A | 1z11C-4grcA:undetectable | 1z11C-4grcA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gs1 | DYP-TYPE PEROXIDASE (Thermobifidacellulosilytica) |
PF04261(Dyp_perox) | 5 | PHE A 373VAL A 276GLY A 383LEU A 165PHE A 168 | HEM A 501 (-4.0A)NoneNoneGOL A 503 (-3.8A)None | 0.85A | 1z11C-4gs1A:undetectable | 1z11C-4gs1A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gt2 | PUTATIVEUNCHARACTERIZEDPROTEIN SCO3963 (Streptomycescoelicolor) |
no annotation | 5 | PHE B 390VAL B 290GLY B 400LEU B 177PHE B 180 | HEM B 501 (-3.9A)NoneNoneNoneNone | 0.85A | 1z11C-4gt2B:undetectable | 1z11C-4gt2B:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ine | PROTEIN PMT-2 (Caenorhabditiselegans) |
PF08241(Methyltransf_11) | 5 | PHE A 287ILE A 253GLY A 232ILE A 304LEU A 310 | NoneNoneSAH A 501 (-3.6A)SAH A 501 ( 4.5A)None | 1.05A | 1z11C-4ineA:undetectable | 1z11C-4ineA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l60 | PROLIFERATING CELLNUCLEAR ANTIGEN (Saccharomycescerevisiae) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | ASN A 159ILE A 158ILE A 227LEU A 229PHE A 237 | None | 1.09A | 1z11C-4l60A:undetectable | 1z11C-4l60A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4li3 | CYSTEINE SYNTHASE (Haemophilusinfluenzae) |
PF00291(PALP) | 5 | VAL X 109ILE X 75GLY X 74THR X 69LEU X 111 | None | 1.08A | 1z11C-4li3X:undetectable | 1z11C-4li3X:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mn8 | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | VAL A 693ILE A 689ILE A 641LEU A 669PHE A 680 | None | 1.10A | 1z11C-4mn8A:undetectable | 1z11C-4mn8A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mna | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | VAL A 693ILE A 689ILE A 641LEU A 669PHE A 680 | None | 1.10A | 1z11C-4mnaA:undetectable | 1z11C-4mnaA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pay | SIDC, INTERAPTIN (Legionellapneumophila) |
no annotation | 5 | VAL A 233ILE A 306GLY A 307ILE A 313LEU A 259 | None | 1.04A | 1z11C-4payA:undetectable | 1z11C-4payA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0v | FE-HYDROGENASE (Chlamydomonasreinhardtii) |
PF02256(Fe_hyd_SSU)PF02906(Fe_hyd_lg_C) | 5 | PHE A 124ILE A 252THR A 254ILE A 99LEU A 115 | None | 0.98A | 1z11C-4r0vA:undetectable | 1z11C-4r0vA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkz | PUTATIVEUNCHARACTERIZEDPROTEIN TA1305 (Thermoplasmaacidophilum) |
no annotation | 6 | PHE A 89VAL A 94ILE A 6THR A 50ILE A 115LEU A 78 | None | 1.50A | 1z11C-4rkzA:undetectable | 1z11C-4rkzA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx8 | PROBABLE CHITINASE A (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 5 | ILE A 182GLY A 181THR A 184ILE A 222LEU A 218 | None | 0.91A | 1z11C-4tx8A:undetectable | 1z11C-4tx8A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udn | PERIPLASMIC SOLUTEBINDING PROTEIN (CandidatusLiberibacterasiaticus) |
PF01297(ZnuA) | 5 | VAL A 7ILE A 14GLY A 15ILE A 21LEU A 125 | None | 0.88A | 1z11C-4udnA:undetectable | 1z11C-4udnA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w7g | DYNEIN LIGHTINTERMEDIATE CHAIN (Chaetomiumthermophilum) |
PF05783(DLIC) | 5 | VAL A 166ILE A 129THR A 138ILE A 140LEU A 163 | None | 1.01A | 1z11C-4w7gA:undetectable | 1z11C-4w7gA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbd | BSHC (Bacillussubtilis) |
PF10079(BshC) | 6 | PHE A 520PHE A 519ILE A 508THR A 102ILE A 106PHE A 222 | None | 1.37A | 1z11C-4wbdA:undetectable | 1z11C-4wbdA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wmy | INTELECTIN-1 (Homo sapiens) |
no annotation | 5 | ILE A 149GLY A 148THR A 171LEU A 183PHE A 238 | None | 1.14A | 1z11C-4wmyA:undetectable | 1z11C-4wmyA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yfj | AMINOGLYCOSIDE3'-N-ACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 5 | VAL A 112ILE A 26GLY A 120ILE A 126LEU A 110 | SO4 A 204 ( 4.5A)NoneSO4 A 201 (-3.1A)NoneSO4 A 204 (-4.4A) | 1.13A | 1z11C-4yfjA:undetectable | 1z11C-4yfjA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9n | AMINO ACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Brucella ovis) |
PF00497(SBP_bac_3) | 5 | ILE A 201GLY A 106ILE A 128LEU A 123PHE A 144 | None | 1.13A | 1z11C-4z9nA:undetectable | 1z11C-4z9nA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqg | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Moraxellacatarrhalis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | VAL A 101ILE A 17GLY A 18ILE A 24LEU A 287 | NoneNAD A 501 (-3.9A)NoneNoneNone | 0.98A | 1z11C-4zqgA:undetectable | 1z11C-4zqgA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA+,K+-ATPASE BETASUBUNIT (Squalusacanthias) |
PF00287(Na_K-ATPase) | 5 | PHE B 187ASN B 284ILE B 285GLY B 282LEU B 242 | None | 0.94A | 1z11C-5aw4B:undetectable | 1z11C-5aw4B:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6u | AMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF12897(Aminotran_MocR) | 5 | PHE A 216PHE A 252ILE A 107ILE A 151PHE A 132 | None | 1.08A | 1z11C-5c6uA:undetectable | 1z11C-5c6uA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ejs | MYOSIN-I HEAVY CHAIN (Dictyosteliumdiscoideum) |
PF00373(FERM_M)PF00784(MyTH4)PF09380(FERM_C) | 5 | PHE A2142VAL A2089ILE A2082THR A2080ILE A2076 | None | 1.11A | 1z11C-5ejsA:undetectable | 1z11C-5ejsA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fw4 | DYE-DECOLORIZINGPEROXIDASE TFU_3078 (Thermobifidafusca) |
PF04261(Dyp_perox) | 5 | PHE A 336VAL A 239GLY A 346LEU A 128PHE A 131 | HEM A 401 ( 4.0A)NoneNoneNoneNone | 0.86A | 1z11C-5fw4A:undetectable | 1z11C-5fw4A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h4e | BETA 1-3 GLUCANASE (Clostridiumbeijerinckii) |
no annotation | 5 | VAL A 473ILE A 491GLY A 493ILE A 448PHE A 525 | None | 0.97A | 1z11C-5h4eA:undetectable | 1z11C-5h4eA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hcc | COMPLEMENT C5 (Homo sapiens) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF07677(A2M_recep)PF07678(A2M_comp) | 5 | ILE A1381THR A1383ILE A1479LEU A1428PHE A1477 | None | 1.13A | 1z11C-5hccA:undetectable | 1z11C-5hccA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB2 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4)PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | PHE B 758ILE B1055GLY B1054ILE A 670LEU A 805 | None | 0.89A | 1z11C-5ip9B:undetectable | 1z11C-5ip9B:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbg | LGP2 (Gallus gallus) |
PF00271(Helicase_C)PF04851(ResIII)PF11648(RIG-I_C-RD) | 5 | VAL A 370ILE A 355ILE A 396LEU A 432PHE A 360 | None | 1.09A | 1z11C-5jbgA:undetectable | 1z11C-5jbgA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5map | DTPA (Streptomyceslividans) |
PF04261(Dyp_perox) | 5 | PHE A 390VAL A 290GLY A 400LEU A 177PHE A 180 | HEM A 901 (-3.8A)NoneNoneNoneNone | 0.85A | 1z11C-5mapA:undetectable | 1z11C-5mapA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swk | E3 UBIQUITIN-PROTEINLIGASE MDM2 (Homo sapiens) |
no annotation | 5 | ILE A 61GLY A 58ILE A 103LEU A 34PHE A 86 | None | 1.14A | 1z11C-5swkA:undetectable | 1z11C-5swkA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7s | GLYCOSIDE HYDROLASEFAMILY 31ALPHA-GLUCOSIDASE (Paenibacillussp. 598K) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF16990(CBM_35)PF17137(DUF5110) | 5 | PHE A1135VAL A1275ILE A1190GLY A1259LEU A1130 | None | 1.07A | 1z11C-5x7sA:undetectable | 1z11C-5x7sA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnw | ADENYLATE CYCLASEEXOY (Pseudomonasaeruginosa) |
no annotation | 5 | PHE A 306VAL A 333GLY A 62ILE A 346LEU A 342 | None | 1.13A | 1z11C-5xnwA:undetectable | 1z11C-5xnwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsq | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 5 | ILE A 8THR A 42ILE A 22LEU A 32PHE A 83 | None | 1.11A | 1z11C-5xsqA:undetectable | 1z11C-5xsqA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsy | SODIUM CHANNELPROTEIN (Electrophoruselectricus) |
PF00520(Ion_trans)PF06512(Na_trans_assoc) | 5 | PHE A 785ASN A1257ILE A1260GLY A1261LEU A 790 | None | 1.01A | 1z11C-5xsyA:undetectable | 1z11C-5xsyA:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yqw | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio harveyi) |
no annotation | 5 | VAL A 405ILE A 481ILE A 382LEU A 355PHE A 269 | None | 1.06A | 1z11C-5yqwA:undetectable | 1z11C-5yqwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zut | PROLIFERATING CELLNUCLEAR ANTIGEN (Saccharomycescerevisiae) |
no annotation | 5 | ASN A 159ILE A 158ILE A 227LEU A 229PHE A 237 | None | 1.09A | 1z11C-5zutA:undetectable | 1z11C-5zutA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ams | BETA SLIDING CLAMP (Pseudomonasaeruginosa) |
no annotation | 5 | PHE A 233VAL A 215ILE A 224ILE A 139LEU A 208 | None | 1.04A | 1z11C-6amsA:undetectable | 1z11C-6amsA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d2k | FERM, ARHGEF ANDPLECKSTRINDOMAIN-CONTAININGPROTEIN 2 (Mus musculus) |
no annotation | 5 | PHE A 309GLY A 252ILE A 282LEU A 273PHE A 280 | None | 0.97A | 1z11C-6d2kA:undetectable | 1z11C-6d2kA:undetectable |