SIMILAR PATTERNS OF AMINO ACIDS FOR 1Z11_A_8MOA501_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a4e | CATALASE A (Saccharomycescerevisiae) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | PHE A 127PHE A 108ILE A 313ILE A 266LEU A 262 | None | 1.01A | 1z11A-1a4eA:0.0 | 1z11A-1a4eA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7j | PHOSPHORIBULOKINASE (Rhodobactersphaeroides) |
PF00485(PRK) | 5 | PHE A 25VAL A 21ILE A 152GLY A 153LEU A 268 | None | 0.84A | 1z11A-1a7jA:0.0 | 1z11A-1a7jA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i8k | EPIDERMAL GROWTHFACTOR RECEPTORANTIBODY MR1SCFVHEAVY CHAIN (Mus musculus) |
PF07686(V-set) | 6 | PHE B 329ASN B 374GLY B 355THR B 358ILE B 370LEU B 379 | None | 1.42A | 1z11A-1i8kB:0.0 | 1z11A-1i8kB:14.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmo | HEPARIN COFACTOR II (Homo sapiens) |
PF00079(Serpin) | 5 | VAL A 221PHE A 217GLY A 144ILE A 270LEU A 205 | None | 0.91A | 1z11A-1jmoA:0.0 | 1z11A-1jmoA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m93 | SERINE PROTEINASEINHIBITOR 2SERINE PROTEINASEINHIBITOR 2 (Cowpox virus;Cowpox virus) |
PF00079(Serpin)PF00079(Serpin) | 5 | VAL B 198PHE C 318THR B 291ILE B 284PHE B 238 | None | 0.95A | 1z11A-1m93B:0.0 | 1z11A-1m93B:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nj8 | PROLINE-TRNASYNTHETASE (Methanocaldococcusjannaschii) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09181(ProRS-C_2) | 5 | PHE A 178PHE A 177GLY A 251ILE A 127PHE A 41 | None | 1.04A | 1z11A-1nj8A:undetectable | 1z11A-1nj8A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rjl | OUTER SURFACEPROTEIN B (Borreliellaburgdorferi) |
PF00820(Lipoprotein_1) | 5 | VAL C 224PHE C 260ILE C 205ILE C 248LEU C 246 | None | 1.00A | 1z11A-1rjlC:0.0 | 1z11A-1rjlC:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rlm | PHOSPHATASE (Escherichiacoli) |
PF08282(Hydrolase_3) | 5 | PHE A 149PHE A 104ILE A 93GLY A 94ILE A 172 | None | 1.01A | 1z11A-1rlmA:0.0 | 1z11A-1rlmA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vpk | DNA POLYMERASE III,BETA SUBUNIT (Thermotogamaritima) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | PHE A 35PHE A 42ILE A 14ILE A 98LEU A 89 | None | 0.98A | 1z11A-1vpkA:undetectable | 1z11A-1vpkA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wy2 | XAA-PRO DIPEPTIDASE (Pyrococcushorikoshii) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 5 | VAL A 167ILE A 151THR A 346ILE A 224LEU A 213 | None | 1.05A | 1z11A-1wy2A:undetectable | 1z11A-1wy2A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xg2 | PECTINESTERASE 1 (Solanumlycopersicum) |
PF01095(Pectinesterase) | 5 | VAL A 309ASN A 123ILE A 122ILE A 298LEU A 304 | None | 0.98A | 1z11A-1xg2A:undetectable | 1z11A-1xg2A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yy3 | S-ADENOSYLMETHIONINE:TRNARIBOSYLTRANSFERASE-ISOMERASE (Bacillussubtilis) |
PF02547(Queuosine_synth) | 5 | VAL A 197ILE A 47ILE A 295LEU A 56PHE A 184 | None | 0.85A | 1z11A-1yy3A:undetectable | 1z11A-1yy3A:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk5 | F17G ADHESIN SUBUNIT (Escherichiacoli) |
PF09222(Fim-adh_lectin) | 5 | VAL A 139PHE A 171GLY A 75ILE A 144LEU A 168 | None | 1.06A | 1z11A-1zk5A:undetectable | 1z11A-1zk5A:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aja | ANKYRIN REPEATFAMILY PROTEIN (Legionellapneumophila) |
no annotation | 5 | ASN A 284GLY A 236ILE A 215LEU A 219PHE A 202 | None | 1.06A | 1z11A-2ajaA:undetectable | 1z11A-2ajaA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f8t | ARGONAUTE PROTEIN (Aquifexaeolicus) |
PF02171(Piwi) | 5 | PHE A 88PHE A 21GLY A 302LEU A 100PHE A 91 | None | 0.89A | 1z11A-2f8tA:undetectable | 1z11A-2f8tA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2igf | IGG1-KAPPA B13I2 FAB(HEAVY CHAIN) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 6 | PHE H 29ASN H 73GLY H 54THR H 57ILE H 69LEU H 78 | None | 1.45A | 1z11A-2igfH:undetectable | 1z11A-2igfH:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ipc | PREPROTEINTRANSLOCASE SECASUBUNIT (Thermusthermophilus) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 5 | PHE A 293GLY A 279THR A 261ILE A 308LEU A 304 | None | 0.93A | 1z11A-2ipcA:undetectable | 1z11A-2ipcA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n0s | FE-HYDROGENASE (Chlamydomonasreinhardtii) |
PF02256(Fe_hyd_SSU)PF02906(Fe_hyd_lg_C) | 5 | PHE A 84ILE A 212THR A 214ILE A 59LEU A 75 | None | 1.03A | 1z11A-2n0sA:undetectable | 1z11A-2n0sA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p54 | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | PHE A 365PHE A 361ILE A 382LEU A 433PHE A 378 | None | 1.06A | 1z11A-2p54A:undetectable | 1z11A-2p54A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbf | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASEBETA-ASPARTATEMETHYLTRANSFERASE (Plasmodiumfalciparum) |
PF01135(PCMT) | 5 | ILE A 113GLY A 114THR A 95ILE A 129LEU A 126 | None | 1.05A | 1z11A-2pbfA:undetectable | 1z11A-2pbfA:20.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pg6 | CYTOCHROME P450 2A6 (Homo sapiens) |
PF00067(p450) | 10 | PHE A 107PHE A 111VAL A 117PHE A 118ILE A 300GLY A 301THR A 305ILE A 366LEU A 370PHE A 480 | NoneNoneHEM A 500 (-3.7A)NoneNoneHEM A 500 ( 4.7A)HEM A 500 (-3.6A)HEM A 500 ( 4.1A)HEM A 500 ( 3.8A)None | 0.29A | 1z11A-2pg6A:65.2 | 1z11A-2pg6A:99.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5j | MAJOR CAPSID PROTEINL1 (Alphapapillomavirus9) |
PF00500(Late_protein_L1) | 5 | PHE A 372PHE A 374ILE A 159GLY A 160LEU A 77 | None | 1.00A | 1z11A-2r5jA:undetectable | 1z11A-2r5jA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9y | FATTY ACID/RETINOLBINDING PROTEINPROTEIN 7, ISOFORMA, CONFIRMED BYTRANSCRIPT EVIDENCE (Caenorhabditiselegans) |
PF05823(Gp-FAR-1) | 5 | VAL A 53THR A 101ILE A 25LEU A 60PHE A 21 | None | 0.91A | 1z11A-2w9yA:undetectable | 1z11A-2w9yA:13.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bn9 | E2 FAB HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 6 | PHE D 29ASN D 73GLY D 54THR D 57ILE D 69LEU D 78 | None | 1.48A | 1z11A-3bn9D:undetectable | 1z11A-3bn9D:17.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bpt | 3-HYDROXYISOBUTYRYL-COA HYDROLASE (Homo sapiens) |
PF16113(ECH_2) | 5 | PHE A 117PHE A 118GLY A 97ILE A 172LEU A 174 | NoneHIU A 502 (-4.8A)HIU A 502 ( 3.5A)QUE A 501 (-3.9A)HIU A 502 (-4.9A) | 1.05A | 1z11A-3bptA:undetectable | 1z11A-3bptA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxv | SULFUROXYGENASE/REDUCTASE (Acidianustengchongensis) |
PF07682(SOR) | 5 | VAL A 252ILE A 290GLY A 164ILE A 180LEU A 184 | None | 1.06A | 1z11A-3bxvA:undetectable | 1z11A-3bxvA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c2g | SYS-1 PROTEIN (Caenorhabditiselegans) |
no annotation | 5 | VAL A 460ILE A 468GLY A 466LEU A 496PHE A 527 | None | 0.99A | 1z11A-3c2gA:undetectable | 1z11A-3c2gA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cxm | URACIL-DNAGLYCOSYLASE (Leishmanianaiffi) |
PF03167(UDG) | 6 | PHE A 287PHE A 162THR A 269ILE A 186LEU A 136PHE A 187 | None | 1.42A | 1z11A-3cxmA:undetectable | 1z11A-3cxmA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3da1 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE (Bacillushalodurans) |
PF01266(DAO)PF16901(DAO_C) | 5 | VAL A 232ASN A 226ILE A 369ILE A 343LEU A 247 | None | 1.07A | 1z11A-3da1A:undetectable | 1z11A-3da1A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkh | LACCASE-1 (Melanocarpusalbomyces) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | PHE A 288VAL A 217PHE A 310ILE A 200LEU A 227 | NoneNAG A 760 (-3.9A)NoneNoneNone | 0.89A | 1z11A-3dkhA:undetectable | 1z11A-3dkhA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3x | BIPA (Vibrioparahaemolyticus) |
PF00679(EFG_C) | 5 | PHE A 179PHE A 175ASN A 142ILE A 139GLY A 138 | None | 1.04A | 1z11A-3e3xA:undetectable | 1z11A-3e3xA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ed4 | ARYLSULFATASE (Escherichiacoli) |
PF00884(Sulfatase) | 5 | VAL A 241ASN A 288THR A 68LEU A 53PHE A 316 | None | 1.04A | 1z11A-3ed4A:undetectable | 1z11A-3ed4A:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ihy | PHOSPHATIDYLINOSITOL3-KINASE CATALYTICSUBUNIT TYPE 3 (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka) | 5 | VAL A 842PHE A 820ILE A 765GLY A 740ILE A 735 | None | 1.03A | 1z11A-3ihyA:undetectable | 1z11A-3ihyA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k17 | LIN0012 PROTEIN (Listeriainnocua) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | PHE A 137ILE A 66GLY A 67ILE A 84LEU A 133 | None | 1.01A | 1z11A-3k17A:undetectable | 1z11A-3k17A:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k74 | NANOBODY (Lama glama) |
PF07686(V-set) | 6 | PHE B 188ASN B 233GLY B 214THR B 217ILE B 229LEU B 238 | None | 1.44A | 1z11A-3k74B:undetectable | 1z11A-3k74B:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kkc | TETR FAMILYTRANSCRIPTIONALREGULATOR (Streptococcusagalactiae) |
PF00440(TetR_N)PF14278(TetR_C_8) | 5 | PHE A 65PHE A 69ILE A 95ILE A 146LEU A 114 | None | 1.00A | 1z11A-3kkcA:undetectable | 1z11A-3kkcA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kq4 | CUBILIN (Homo sapiens) |
PF00431(CUB) | 5 | PHE B1270PHE B1210PHE B1207LEU B1205PHE B1176 | None | 0.94A | 1z11A-3kq4B:undetectable | 1z11A-3kq4B:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8k | DIHYDROLIPOYLDEHYDROGENASE (Sulfolobussolfataricus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | VAL A 215ILE A 207ILE A 226LEU A 219PHE A 228 | None | 1.04A | 1z11A-3l8kA:undetectable | 1z11A-3l8kA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lca | PROTEIN TOM71 (Saccharomycescerevisiae) |
PF00515(TPR_1)PF13181(TPR_8)PF14559(TPR_19) | 5 | PHE A 273PHE A 276ASN A 379ILE A 353LEU A 302 | None | 1.03A | 1z11A-3lcaA:undetectable | 1z11A-3lcaA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgx | PUTATIVE P450MONOOXYGENASE (Amycolatopsisbalhimycina) |
PF00067(p450) | 5 | VAL A 88ASN A 231ILE A 234GLY A 235THR A 239 | HEM A 397 ( 3.8A)GOL A 399 (-4.2A)GOL A 400 ( 4.0A)GOL A 399 ( 3.6A)HEM A 397 (-3.5A) | 0.89A | 1z11A-3mgxA:29.9 | 1z11A-3mgxA:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n23 | SODIUM/POTASSIUM-TRANSPORTING ATPASESUBUNIT BETA-1 (Sus scrofa) |
PF00287(Na_K-ATPase) | 5 | PHE B 186ASN B 282ILE B 283GLY B 280LEU B 240 | None | 0.89A | 1z11A-3n23B:undetectable | 1z11A-3n23B:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n9x | PHOSPHOTRANSFERASE (Plasmodiumberghei) |
PF00069(Pkinase) | 5 | PHE A 263ILE A 296GLY A 297ILE A 316LEU A 289 | None | 0.98A | 1z11A-3n9xA:undetectable | 1z11A-3n9xA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nie | MAP2 KINASE (Plasmodiumfalciparum) |
PF00069(Pkinase) | 5 | PHE A 268ILE A 301GLY A 302ILE A 321LEU A 294 | None | 1.00A | 1z11A-3nieA:undetectable | 1z11A-3nieA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3odt | PROTEIN DOA1 (Saccharomycescerevisiae) |
PF00400(WD40) | 5 | PHE A 193VAL A 146GLY A 191LEU A 164PHE A 174 | None | 1.00A | 1z11A-3odtA:undetectable | 1z11A-3odtA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q6a | UNCHARACTERIZEDPROTEIN (Staphylococcussaprophyticus) |
PF08327(AHSA1) | 5 | PHE A 31THR A 92ILE A 77LEU A 135PHE A 70 | None | 1.06A | 1z11A-3q6aA:undetectable | 1z11A-3q6aA:14.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u15 | PROTEIN MDM4 (Homo sapiens) |
PF02201(SWIB) | 5 | VAL A 74PHE A 90GLY A 57ILE A 36LEU A 81 | NoneNone03M A 1 ( 4.0A)NoneNone | 1.06A | 1z11A-3u15A:undetectable | 1z11A-3u15A:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 5 | VAL A 132PHE A 31ILE A 110LEU A 9PHE A 106 | None | 0.74A | 1z11A-3umaA:undetectable | 1z11A-3umaA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3unn | MEDIATOR OF DNADAMAGE CHECKPOINTPROTEIN 1 (Homo sapiens) |
PF00498(FHA) | 5 | VAL A 64ILE A 71THR A 98ILE A 121LEU A 34 | None | 1.05A | 1z11A-3unnA:undetectable | 1z11A-3unnA:13.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zks | XA4813 (Lama glama) |
PF07686(V-set) | 6 | PHE D 188ASN D 233GLY D 214THR D 217ILE D 229LEU D 238 | None | 1.48A | 1z11A-3zksD:undetectable | 1z11A-3zksD:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a05 | CELLOBIOHYDROLASEFAMILY 6 (Chaetomiumthermophilum) |
PF01341(Glyco_hydro_6) | 5 | ASN A 129ILE A 196GLY A 195THR A 245LEU A 164 | None | 1.06A | 1z11A-4a05A:undetectable | 1z11A-4a05A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 5 | VAL V1202ILE V1180GLY V1182ILE V1263LEU V1250 | None | 0.97A | 1z11A-4bxsV:undetectable | 1z11A-4bxsV:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzi | SEC23P (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | PHE A 706GLY A 367ILE A 285LEU A 387PHE A 346 | None | 0.96A | 1z11A-4bziA:undetectable | 1z11A-4bziA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c8q | DNA TOPOISOMERASE2-ASSOCIATED PROTEINPAT1 (Saccharomycescerevisiae) |
PF09770(PAT1) | 5 | PHE H 556ILE H 595ILE H 533LEU H 527PHE H 587 | None | 1.04A | 1z11A-4c8qH:undetectable | 1z11A-4c8qH:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dyo | ASPARTYLAMINOPEPTIDASE (Homo sapiens) |
PF02127(Peptidase_M18) | 5 | VAL A 429ILE A 91GLY A 92THR A 296LEU A 427 | None | 1.06A | 1z11A-4dyoA:undetectable | 1z11A-4dyoA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ei8 | PLASMID REPLICATIONPROTEIN REPX (Bacillus cereus) |
PF00091(Tubulin) | 5 | PHE A 94VAL A 89GLY A 22ILE A 74LEU A 76 | None | 0.98A | 1z11A-4ei8A:undetectable | 1z11A-4ei8A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eiu | UNCHARACTERIZEDHYPOTHETICAL PROTEIN (Bacteroidesuniformis) |
PF12866(DUF3823) | 5 | VAL A 58PHE A 75GLY A 36ILE A 123LEU A 60 | None | 0.72A | 1z11A-4eiuA:undetectable | 1z11A-4eiuA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eut | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | VAL A 280ILE A 207GLY A 208LEU A 277PHE A 112 | None | 0.88A | 1z11A-4eutA:undetectable | 1z11A-4eutA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4euu | SERINE/THREONINE-PROTEIN KINASE TBK1 (Homo sapiens) |
PF00069(Pkinase) | 5 | VAL A 280ILE A 207GLY A 208LEU A 277PHE A 112 | None | 0.88A | 1z11A-4euuA:undetectable | 1z11A-4euuA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdw | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidesovatus) |
PF07523(Big_3)PF13306(LRR_5) | 5 | VAL A 151ASN A 170ILE A 138LEU A 135PHE A 159 | None | 0.85A | 1z11A-4fdwA:undetectable | 1z11A-4fdwA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4grc | PUTATIVE MEMBRANEPROTEIN (Streptomycescoelicolor) |
PF04261(Dyp_perox) | 5 | PHE A 363VAL A 274GLY A 373LEU A 165PHE A 168 | HEM A 502 (-3.9A)NoneNoneNoneNone | 0.82A | 1z11A-4grcA:undetectable | 1z11A-4grcA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gs1 | DYP-TYPE PEROXIDASE (Thermobifidacellulosilytica) |
PF04261(Dyp_perox) | 5 | PHE A 373VAL A 276GLY A 383LEU A 165PHE A 168 | HEM A 501 (-4.0A)NoneNoneGOL A 503 (-3.8A)None | 0.84A | 1z11A-4gs1A:undetectable | 1z11A-4gs1A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gt2 | PUTATIVEUNCHARACTERIZEDPROTEIN SCO3963 (Streptomycescoelicolor) |
no annotation | 5 | PHE B 390VAL B 290GLY B 400LEU B 177PHE B 180 | HEM B 501 (-3.9A)NoneNoneNoneNone | 0.83A | 1z11A-4gt2B:undetectable | 1z11A-4gt2B:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kys | THIAMINEPYRIDINYLASE I (Clostridiumbotulinum) |
PF01547(SBP_bac_1) | 5 | PHE A 91PHE A 93GLY A 105ILE A 131LEU A 98 | None | 1.02A | 1z11A-4kysA:undetectable | 1z11A-4kysA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgi | UNCHARACTERIZEDPROTEIN (Escherichiacoli) |
PF13678(Peptidase_M85) | 5 | VAL A 94PHE A 90ILE A 108GLY A 106LEU A 84 | None | 0.97A | 1z11A-4lgiA:undetectable | 1z11A-4lgiA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4li3 | CYSTEINE SYNTHASE (Haemophilusinfluenzae) |
PF00291(PALP) | 5 | VAL X 109ILE X 75GLY X 74THR X 69LEU X 111 | None | 1.03A | 1z11A-4li3X:undetectable | 1z11A-4li3X:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mn8 | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | VAL A 693ILE A 689ILE A 641LEU A 669PHE A 680 | None | 1.06A | 1z11A-4mn8A:undetectable | 1z11A-4mn8A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mna | LRR RECEPTOR-LIKESERINE/THREONINE-PROTEIN KINASE FLS2 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 5 | VAL A 693ILE A 689ILE A 641LEU A 669PHE A 680 | None | 1.05A | 1z11A-4mnaA:undetectable | 1z11A-4mnaA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o2i | NON-LEE ENCODED TYPEIII EFFECTOR C (Citrobacterrodentium) |
PF13678(Peptidase_M85) | 5 | VAL A 94PHE A 90ILE A 108GLY A 106LEU A 84 | None | 0.94A | 1z11A-4o2iA:undetectable | 1z11A-4o2iA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4odw | A6 FAB (IGG2B) HEAVYCHAIN (Mus musculus) |
no annotation | 6 | PHE H 29ASN H 73GLY H 54THR H 57ILE H 69LEU H 78 | None | 1.38A | 1z11A-4odwH:undetectable | 1z11A-4odwH:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0v | FE-HYDROGENASE (Chlamydomonasreinhardtii) |
PF02256(Fe_hyd_SSU)PF02906(Fe_hyd_lg_C) | 5 | PHE A 124ILE A 252THR A 254ILE A 99LEU A 115 | None | 1.02A | 1z11A-4r0vA:undetectable | 1z11A-4r0vA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r72 | ABC-TYPE FE3+TRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Actinobacilluspleuropneumoniae) |
PF13343(SBP_bac_6) | 6 | PHE A 295ILE A 291GLY A 227ILE A 104LEU A 230PHE A 88 | None | 1.44A | 1z11A-4r72A:undetectable | 1z11A-4r72A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r90 | ANTI CD70 LLAMAGLAMA FAB 27B3 HEAVYCHAIN (Lama glama) |
PF07654(C1-set)PF07686(V-set) | 6 | PHE H 29ASN H 74GLY H 55THR H 58ILE H 70LEU H 79 | None | 1.44A | 1z11A-4r90H:undetectable | 1z11A-4r90H:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkz | PUTATIVEUNCHARACTERIZEDPROTEIN TA1305 (Thermoplasmaacidophilum) |
no annotation | 6 | PHE A 89VAL A 94PHE A 85ILE A 6THR A 50LEU A 78 | None | 1.43A | 1z11A-4rkzA:undetectable | 1z11A-4rkzA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx8 | PROBABLE CHITINASE A (Chromobacteriumviolaceum) |
PF00704(Glyco_hydro_18) | 5 | ILE A 182GLY A 181THR A 184ILE A 222LEU A 218 | None | 0.93A | 1z11A-4tx8A:undetectable | 1z11A-4tx8A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udn | PERIPLASMIC SOLUTEBINDING PROTEIN (CandidatusLiberibacterasiaticus) |
PF01297(ZnuA) | 5 | VAL A 7ILE A 14GLY A 15ILE A 21LEU A 125 | None | 0.89A | 1z11A-4udnA:undetectable | 1z11A-4udnA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uu9 | MEDI7814 (Homo sapiens) |
PF07686(V-set) | 6 | PHE A 29ASN A 73GLY A 54THR A 57ILE A 69LEU A 78 | None | 1.46A | 1z11A-4uu9A:undetectable | 1z11A-4uu9A:11.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w7g | DYNEIN LIGHTINTERMEDIATE CHAIN (Chaetomiumthermophilum) |
PF05783(DLIC) | 5 | VAL A 166ILE A 129THR A 138ILE A 140LEU A 163 | None | 1.02A | 1z11A-4w7gA:undetectable | 1z11A-4w7gA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4weu | ANTI-F4+ETECBACTERIA VHHVARIABLE REGION (Lama glama) |
PF07686(V-set) | 6 | PHE D 829ASN D 874GLY D 855THR D 858ILE D 870LEU D 879 | None | 1.44A | 1z11A-4weuD:undetectable | 1z11A-4weuD:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yj1 | UNCHARACTERIZEDPROTEIN (Trypanosomabrucei) |
PF09818(ABC_ATPase) | 5 | VAL A 256PHE A 280THR A 309ILE A 311LEU A 322 | None | 0.94A | 1z11A-4yj1A:undetectable | 1z11A-4yj1A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywo | MERCURIC REDUCTASE (Metallosphaerasedula) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | VAL A 99ILE A 6ILE A 35LEU A 94PHE A 14 | None | 1.00A | 1z11A-4ywoA:undetectable | 1z11A-4ywoA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zqg | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Moraxellacatarrhalis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | VAL A 101ILE A 17GLY A 18ILE A 24LEU A 287 | NoneNAD A 501 (-3.9A)NoneNoneNone | 1.01A | 1z11A-4zqgA:undetectable | 1z11A-4zqgA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA+,K+-ATPASE BETASUBUNIT (Squalusacanthias) |
PF00287(Na_K-ATPase) | 5 | PHE B 187ASN B 284ILE B 285GLY B 282LEU B 242 | None | 0.94A | 1z11A-5aw4B:undetectable | 1z11A-5aw4B:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3n | ANTI-H4K20ME1_SCFV (Mus musculus) |
PF07686(V-set) | 6 | PHE A 31ASN A 76GLY A 57THR A 60ILE A 72LEU A 81 | None | 1.40A | 1z11A-5b3nA:undetectable | 1z11A-5b3nA:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c6u | AMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF12897(Aminotran_MocR) | 5 | PHE A 216PHE A 252ILE A 107ILE A 151PHE A 132 | None | 1.03A | 1z11A-5c6uA:undetectable | 1z11A-5c6uA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6a | PREDICTED ATPASE OFTHE ABC CLASS (Vibriovulnificus) |
PF09818(ABC_ATPase) | 5 | VAL A 186PHE A 209THR A 237ILE A 239LEU A 250 | None | 0.98A | 1z11A-5d6aA:undetectable | 1z11A-5d6aA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5do2 | 4C2 HEAVY CHAIN (Mus musculus) |
no annotation | 6 | PHE H 29ASN H 74GLY H 55THR H 58ILE H 70LEU H 79 | None | 1.33A | 1z11A-5do2H:undetectable | 1z11A-5do2H:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5flz | TUBULIN GAMMA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | PHE C 204VAL C 17ILE C 234THR C 239LEU C 139 | None | 1.04A | 1z11A-5flzC:undetectable | 1z11A-5flzC:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fw4 | DYE-DECOLORIZINGPEROXIDASE TFU_3078 (Thermobifidafusca) |
PF04261(Dyp_perox) | 5 | PHE A 336VAL A 239GLY A 346LEU A 128PHE A 131 | HEM A 401 ( 4.0A)NoneNoneNoneNone | 0.84A | 1z11A-5fw4A:undetectable | 1z11A-5fw4A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h4e | BETA 1-3 GLUCANASE (Clostridiumbeijerinckii) |
no annotation | 5 | VAL A 473ILE A 491GLY A 493ILE A 448PHE A 525 | None | 1.02A | 1z11A-5h4eA:undetectable | 1z11A-5h4eA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB2 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4)PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | PHE B 758ILE B1055GLY B1054ILE A 670LEU A 805 | None | 0.87A | 1z11A-5ip9B:undetectable | 1z11A-5ip9B:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja9 | NANOBODY 6 (Lama glama) |
PF07686(V-set) | 6 | PHE A 30ASN A 75GLY A 56THR A 59ILE A 71LEU A 80 | None | 1.39A | 1z11A-5ja9A:undetectable | 1z11A-5ja9A:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jmo | CAMELID VHH FRAGMENT (Camelusdromedarius) |
PF07686(V-set) | 6 | PHE C 29ASN C 74GLY C 55THR C 58ILE C 70LEU C 79 | None | 1.41A | 1z11A-5jmoC:undetectable | 1z11A-5jmoC:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5map | DTPA (Streptomyceslividans) |
PF04261(Dyp_perox) | 5 | PHE A 390VAL A 290GLY A 400LEU A 177PHE A 180 | HEM A 901 (-3.8A)NoneNoneNoneNone | 0.83A | 1z11A-5mapA:undetectable | 1z11A-5mapA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vk1 | PROTEIN MDM4 (Homo sapiens) |
no annotation | 5 | VAL A 74PHE A 90GLY A 57ILE A 36LEU A 81 | None | 1.06A | 1z11A-5vk1A:undetectable | 1z11A-5vk1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnw | ADENYLATE CYCLASEEXOY (Pseudomonasaeruginosa) |
no annotation | 5 | PHE A 339PHE A 306VAL A 333GLY A 62ILE A 346 | None | 1.05A | 1z11A-5xnwA:undetectable | 1z11A-5xnwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsy | SODIUM CHANNELPROTEIN (Electrophoruselectricus) |
PF00520(Ion_trans)PF06512(Na_trans_assoc) | 5 | PHE A 785ASN A1257ILE A1260GLY A1261LEU A 790 | None | 0.94A | 1z11A-5xsyA:undetectable | 1z11A-5xsyA:14.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9c | MAJOR CAPSID PROTEINL1 (Alphapapillomavirus9) |
no annotation | 5 | PHE A 373PHE A 375ILE A 160GLY A 161LEU A 78 | None | 0.98A | 1z11A-5y9cA:undetectable | 1z11A-5y9cA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yqw | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio harveyi) |
no annotation | 5 | VAL A 405ILE A 481ILE A 382LEU A 355PHE A 269 | None | 1.05A | 1z11A-5yqwA:undetectable | 1z11A-5yqwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d2k | FERM, ARHGEF ANDPLECKSTRINDOMAIN-CONTAININGPROTEIN 2 (Mus musculus) |
no annotation | 5 | PHE A 309GLY A 252ILE A 282LEU A 273PHE A 280 | None | 1.03A | 1z11A-6d2kA:undetectable | 1z11A-6d2kA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fe4 | NB113 (Vicugna pacos) |
no annotation | 6 | PHE F 29ASN F 74GLY F 55THR F 58ILE F 70LEU F 79 | None | 1.46A | 1z11A-6fe4F:undetectable | 1z11A-6fe4F:undetectable |