SIMILAR PATTERNS OF AMINO ACIDS FOR 1Z11_A_8MOA501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a4e CATALASE A

(Saccharomyces
cerevisiae)
PF00199
(Catalase)
PF06628
(Catalase-rel)
5 PHE A 127
PHE A 108
ILE A 313
ILE A 266
LEU A 262
None
1.01A 1z11A-1a4eA:
0.0
1z11A-1a4eA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a7j PHOSPHORIBULOKINASE

(Rhodobacter
sphaeroides)
PF00485
(PRK)
5 PHE A  25
VAL A  21
ILE A 152
GLY A 153
LEU A 268
None
0.84A 1z11A-1a7jA:
0.0
1z11A-1a7jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8k EPIDERMAL GROWTH
FACTOR RECEPTOR
ANTIBODY MR1SCFV
HEAVY CHAIN


(Mus musculus)
PF07686
(V-set)
6 PHE B 329
ASN B 374
GLY B 355
THR B 358
ILE B 370
LEU B 379
None
1.42A 1z11A-1i8kB:
0.0
1z11A-1i8kB:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmo HEPARIN COFACTOR II

(Homo sapiens)
PF00079
(Serpin)
5 VAL A 221
PHE A 217
GLY A 144
ILE A 270
LEU A 205
None
0.91A 1z11A-1jmoA:
0.0
1z11A-1jmoA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m93 SERINE PROTEINASE
INHIBITOR 2
SERINE PROTEINASE
INHIBITOR 2


(Cowpox virus;
Cowpox virus)
PF00079
(Serpin)
PF00079
(Serpin)
5 VAL B 198
PHE C 318
THR B 291
ILE B 284
PHE B 238
None
0.95A 1z11A-1m93B:
0.0
1z11A-1m93B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nj8 PROLINE-TRNA
SYNTHETASE


(Methanocaldococcus
jannaschii)
PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09181
(ProRS-C_2)
5 PHE A 178
PHE A 177
GLY A 251
ILE A 127
PHE A  41
None
1.04A 1z11A-1nj8A:
undetectable
1z11A-1nj8A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rjl OUTER SURFACE
PROTEIN B


(Borreliella
burgdorferi)
PF00820
(Lipoprotein_1)
5 VAL C 224
PHE C 260
ILE C 205
ILE C 248
LEU C 246
None
1.00A 1z11A-1rjlC:
0.0
1z11A-1rjlC:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rlm PHOSPHATASE

(Escherichia
coli)
PF08282
(Hydrolase_3)
5 PHE A 149
PHE A 104
ILE A  93
GLY A  94
ILE A 172
None
1.01A 1z11A-1rlmA:
0.0
1z11A-1rlmA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpk DNA POLYMERASE III,
BETA SUBUNIT


(Thermotoga
maritima)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 PHE A  35
PHE A  42
ILE A  14
ILE A  98
LEU A  89
None
0.98A 1z11A-1vpkA:
undetectable
1z11A-1vpkA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy2 XAA-PRO DIPEPTIDASE

(Pyrococcus
horikoshii)
PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
5 VAL A 167
ILE A 151
THR A 346
ILE A 224
LEU A 213
None
1.05A 1z11A-1wy2A:
undetectable
1z11A-1wy2A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg2 PECTINESTERASE 1

(Solanum
lycopersicum)
PF01095
(Pectinesterase)
5 VAL A 309
ASN A 123
ILE A 122
ILE A 298
LEU A 304
None
0.98A 1z11A-1xg2A:
undetectable
1z11A-1xg2A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yy3 S-ADENOSYLMETHIONINE
:TRNA
RIBOSYLTRANSFERASE-I
SOMERASE


(Bacillus
subtilis)
PF02547
(Queuosine_synth)
5 VAL A 197
ILE A  47
ILE A 295
LEU A  56
PHE A 184
None
0.85A 1z11A-1yy3A:
undetectable
1z11A-1yy3A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zk5 F17G ADHESIN SUBUNIT

(Escherichia
coli)
PF09222
(Fim-adh_lectin)
5 VAL A 139
PHE A 171
GLY A  75
ILE A 144
LEU A 168
None
1.06A 1z11A-1zk5A:
undetectable
1z11A-1zk5A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aja ANKYRIN REPEAT
FAMILY PROTEIN


(Legionella
pneumophila)
no annotation 5 ASN A 284
GLY A 236
ILE A 215
LEU A 219
PHE A 202
None
1.06A 1z11A-2ajaA:
undetectable
1z11A-2ajaA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8t ARGONAUTE PROTEIN

(Aquifex
aeolicus)
PF02171
(Piwi)
5 PHE A  88
PHE A  21
GLY A 302
LEU A 100
PHE A  91
None
0.89A 1z11A-2f8tA:
undetectable
1z11A-2f8tA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2igf IGG1-KAPPA B13I2 FAB
(HEAVY CHAIN)


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
6 PHE H  29
ASN H  73
GLY H  54
THR H  57
ILE H  69
LEU H  78
None
1.45A 1z11A-2igfH:
undetectable
1z11A-2igfH:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT


(Thermus
thermophilus)
PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD)
5 PHE A 293
GLY A 279
THR A 261
ILE A 308
LEU A 304
None
0.93A 1z11A-2ipcA:
undetectable
1z11A-2ipcA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n0s FE-HYDROGENASE

(Chlamydomonas
reinhardtii)
PF02256
(Fe_hyd_SSU)
PF02906
(Fe_hyd_lg_C)
5 PHE A  84
ILE A 212
THR A 214
ILE A  59
LEU A  75
None
1.03A 1z11A-2n0sA:
undetectable
1z11A-2n0sA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p54 PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA


(Homo sapiens)
PF00104
(Hormone_recep)
5 PHE A 365
PHE A 361
ILE A 382
LEU A 433
PHE A 378
None
1.06A 1z11A-2p54A:
undetectable
1z11A-2p54A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE


(Plasmodium
falciparum)
PF01135
(PCMT)
5 ILE A 113
GLY A 114
THR A  95
ILE A 129
LEU A 126
None
1.05A 1z11A-2pbfA:
undetectable
1z11A-2pbfA:
20.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pg6 CYTOCHROME P450 2A6

(Homo sapiens)
PF00067
(p450)
10 PHE A 107
PHE A 111
VAL A 117
PHE A 118
ILE A 300
GLY A 301
THR A 305
ILE A 366
LEU A 370
PHE A 480
None
None
HEM  A 500 (-3.7A)
None
None
HEM  A 500 ( 4.7A)
HEM  A 500 (-3.6A)
HEM  A 500 ( 4.1A)
HEM  A 500 ( 3.8A)
None
0.29A 1z11A-2pg6A:
65.2
1z11A-2pg6A:
99.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r5j MAJOR CAPSID PROTEIN
L1


(Alphapapillomavirus
9)
PF00500
(Late_protein_L1)
5 PHE A 372
PHE A 374
ILE A 159
GLY A 160
LEU A  77
None
1.00A 1z11A-2r5jA:
undetectable
1z11A-2r5jA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w9y FATTY ACID/RETINOL
BINDING PROTEIN
PROTEIN 7, ISOFORM
A, CONFIRMED BY
TRANSCRIPT EVIDENCE


(Caenorhabditis
elegans)
PF05823
(Gp-FAR-1)
5 VAL A  53
THR A 101
ILE A  25
LEU A  60
PHE A  21
None
0.91A 1z11A-2w9yA:
undetectable
1z11A-2w9yA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn9 E2 FAB HEAVY CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
6 PHE D  29
ASN D  73
GLY D  54
THR D  57
ILE D  69
LEU D  78
None
1.48A 1z11A-3bn9D:
undetectable
1z11A-3bn9D:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bpt 3-HYDROXYISOBUTYRYL-
COA HYDROLASE


(Homo sapiens)
PF16113
(ECH_2)
5 PHE A 117
PHE A 118
GLY A  97
ILE A 172
LEU A 174
None
HIU  A 502 (-4.8A)
HIU  A 502 ( 3.5A)
QUE  A 501 (-3.9A)
HIU  A 502 (-4.9A)
1.05A 1z11A-3bptA:
undetectable
1z11A-3bptA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxv SULFUR
OXYGENASE/REDUCTASE


(Acidianus
tengchongensis)
PF07682
(SOR)
5 VAL A 252
ILE A 290
GLY A 164
ILE A 180
LEU A 184
None
1.06A 1z11A-3bxvA:
undetectable
1z11A-3bxvA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2g SYS-1 PROTEIN

(Caenorhabditis
elegans)
no annotation 5 VAL A 460
ILE A 468
GLY A 466
LEU A 496
PHE A 527
None
0.99A 1z11A-3c2gA:
undetectable
1z11A-3c2gA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxm URACIL-DNA
GLYCOSYLASE


(Leishmania
naiffi)
PF03167
(UDG)
6 PHE A 287
PHE A 162
THR A 269
ILE A 186
LEU A 136
PHE A 187
None
1.42A 1z11A-3cxmA:
undetectable
1z11A-3cxmA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3da1 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE


(Bacillus
halodurans)
PF01266
(DAO)
PF16901
(DAO_C)
5 VAL A 232
ASN A 226
ILE A 369
ILE A 343
LEU A 247
None
1.07A 1z11A-3da1A:
undetectable
1z11A-3da1A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkh LACCASE-1

(Melanocarpus
albomyces)
PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3)
5 PHE A 288
VAL A 217
PHE A 310
ILE A 200
LEU A 227
None
NAG  A 760 (-3.9A)
None
None
None
0.89A 1z11A-3dkhA:
undetectable
1z11A-3dkhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3x BIPA

(Vibrio
parahaemolyticus)
PF00679
(EFG_C)
5 PHE A 179
PHE A 175
ASN A 142
ILE A 139
GLY A 138
None
1.04A 1z11A-3e3xA:
undetectable
1z11A-3e3xA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed4 ARYLSULFATASE

(Escherichia
coli)
PF00884
(Sulfatase)
5 VAL A 241
ASN A 288
THR A  68
LEU A  53
PHE A 316
None
1.04A 1z11A-3ed4A:
undetectable
1z11A-3ed4A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihy PHOSPHATIDYLINOSITOL
3-KINASE CATALYTIC
SUBUNIT TYPE 3


(Homo sapiens)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
5 VAL A 842
PHE A 820
ILE A 765
GLY A 740
ILE A 735
None
1.03A 1z11A-3ihyA:
undetectable
1z11A-3ihyA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k17 LIN0012 PROTEIN

(Listeria
innocua)
PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
5 PHE A 137
ILE A  66
GLY A  67
ILE A  84
LEU A 133
None
1.01A 1z11A-3k17A:
undetectable
1z11A-3k17A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k74 NANOBODY

(Lama glama)
PF07686
(V-set)
6 PHE B 188
ASN B 233
GLY B 214
THR B 217
ILE B 229
LEU B 238
None
1.44A 1z11A-3k74B:
undetectable
1z11A-3k74B:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkc TETR FAMILY
TRANSCRIPTIONAL
REGULATOR


(Streptococcus
agalactiae)
PF00440
(TetR_N)
PF14278
(TetR_C_8)
5 PHE A  65
PHE A  69
ILE A  95
ILE A 146
LEU A 114
None
1.00A 1z11A-3kkcA:
undetectable
1z11A-3kkcA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kq4 CUBILIN

(Homo sapiens)
PF00431
(CUB)
5 PHE B1270
PHE B1210
PHE B1207
LEU B1205
PHE B1176
None
0.94A 1z11A-3kq4B:
undetectable
1z11A-3kq4B:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8k DIHYDROLIPOYL
DEHYDROGENASE


(Sulfolobus
solfataricus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
5 VAL A 215
ILE A 207
ILE A 226
LEU A 219
PHE A 228
None
1.04A 1z11A-3l8kA:
undetectable
1z11A-3l8kA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lca PROTEIN TOM71

(Saccharomyces
cerevisiae)
PF00515
(TPR_1)
PF13181
(TPR_8)
PF14559
(TPR_19)
5 PHE A 273
PHE A 276
ASN A 379
ILE A 353
LEU A 302
None
1.03A 1z11A-3lcaA:
undetectable
1z11A-3lcaA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgx PUTATIVE P450
MONOOXYGENASE


(Amycolatopsis
balhimycina)
PF00067
(p450)
5 VAL A  88
ASN A 231
ILE A 234
GLY A 235
THR A 239
HEM  A 397 ( 3.8A)
GOL  A 399 (-4.2A)
GOL  A 400 ( 4.0A)
GOL  A 399 ( 3.6A)
HEM  A 397 (-3.5A)
0.89A 1z11A-3mgxA:
29.9
1z11A-3mgxA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n23 SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT BETA-1


(Sus scrofa)
PF00287
(Na_K-ATPase)
5 PHE B 186
ASN B 282
ILE B 283
GLY B 280
LEU B 240
None
0.89A 1z11A-3n23B:
undetectable
1z11A-3n23B:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9x PHOSPHOTRANSFERASE

(Plasmodium
berghei)
PF00069
(Pkinase)
5 PHE A 263
ILE A 296
GLY A 297
ILE A 316
LEU A 289
None
0.98A 1z11A-3n9xA:
undetectable
1z11A-3n9xA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nie MAP2 KINASE

(Plasmodium
falciparum)
PF00069
(Pkinase)
5 PHE A 268
ILE A 301
GLY A 302
ILE A 321
LEU A 294
None
1.00A 1z11A-3nieA:
undetectable
1z11A-3nieA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odt PROTEIN DOA1

(Saccharomyces
cerevisiae)
PF00400
(WD40)
5 PHE A 193
VAL A 146
GLY A 191
LEU A 164
PHE A 174
None
1.00A 1z11A-3odtA:
undetectable
1z11A-3odtA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6a UNCHARACTERIZED
PROTEIN


(Staphylococcus
saprophyticus)
PF08327
(AHSA1)
5 PHE A  31
THR A  92
ILE A  77
LEU A 135
PHE A  70
None
1.06A 1z11A-3q6aA:
undetectable
1z11A-3q6aA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u15 PROTEIN MDM4

(Homo sapiens)
PF02201
(SWIB)
5 VAL A  74
PHE A  90
GLY A  57
ILE A  36
LEU A  81
None
None
03M  A   1 ( 4.0A)
None
None
1.06A 1z11A-3u15A:
undetectable
1z11A-3u15A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uma HYPOTHETICAL
PEROXIREDOXIN
PROTEIN


(Sinorhizobium
meliloti)
PF08534
(Redoxin)
5 VAL A 132
PHE A  31
ILE A 110
LEU A   9
PHE A 106
None
0.74A 1z11A-3umaA:
undetectable
1z11A-3umaA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3unn MEDIATOR OF DNA
DAMAGE CHECKPOINT
PROTEIN 1


(Homo sapiens)
PF00498
(FHA)
5 VAL A  64
ILE A  71
THR A  98
ILE A 121
LEU A  34
None
1.05A 1z11A-3unnA:
undetectable
1z11A-3unnA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zks XA4813

(Lama glama)
PF07686
(V-set)
6 PHE D 188
ASN D 233
GLY D 214
THR D 217
ILE D 229
LEU D 238
None
1.48A 1z11A-3zksD:
undetectable
1z11A-3zksD:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a05 CELLOBIOHYDROLASE
FAMILY 6


(Chaetomium
thermophilum)
PF01341
(Glyco_hydro_6)
5 ASN A 129
ILE A 196
GLY A 195
THR A 245
LEU A 164
None
1.06A 1z11A-4a05A:
undetectable
1z11A-4a05A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT


(Pseudonaja
textilis)
PF00754
(F5_F8_type_C)
PF07732
(Cu-oxidase_3)
5 VAL V1202
ILE V1180
GLY V1182
ILE V1263
LEU V1250
None
0.97A 1z11A-4bxsV:
undetectable
1z11A-4bxsV:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzi SEC23P

(Saccharomyces
cerevisiae)
PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS)
5 PHE A 706
GLY A 367
ILE A 285
LEU A 387
PHE A 346
None
0.96A 1z11A-4bziA:
undetectable
1z11A-4bziA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c8q DNA TOPOISOMERASE
2-ASSOCIATED PROTEIN
PAT1


(Saccharomyces
cerevisiae)
PF09770
(PAT1)
5 PHE H 556
ILE H 595
ILE H 533
LEU H 527
PHE H 587
None
1.04A 1z11A-4c8qH:
undetectable
1z11A-4c8qH:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyo ASPARTYL
AMINOPEPTIDASE


(Homo sapiens)
PF02127
(Peptidase_M18)
5 VAL A 429
ILE A  91
GLY A  92
THR A 296
LEU A 427
None
1.06A 1z11A-4dyoA:
undetectable
1z11A-4dyoA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei8 PLASMID REPLICATION
PROTEIN REPX


(Bacillus cereus)
PF00091
(Tubulin)
5 PHE A  94
VAL A  89
GLY A  22
ILE A  74
LEU A  76
None
0.98A 1z11A-4ei8A:
undetectable
1z11A-4ei8A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eiu UNCHARACTERIZED
HYPOTHETICAL PROTEIN


(Bacteroides
uniformis)
PF12866
(DUF3823)
5 VAL A  58
PHE A  75
GLY A  36
ILE A 123
LEU A  60
None
0.72A 1z11A-4eiuA:
undetectable
1z11A-4eiuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eut SERINE/THREONINE-PRO
TEIN KINASE TBK1


(Homo sapiens)
PF00069
(Pkinase)
5 VAL A 280
ILE A 207
GLY A 208
LEU A 277
PHE A 112
None
0.88A 1z11A-4eutA:
undetectable
1z11A-4eutA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4euu SERINE/THREONINE-PRO
TEIN KINASE TBK1


(Homo sapiens)
PF00069
(Pkinase)
5 VAL A 280
ILE A 207
GLY A 208
LEU A 277
PHE A 112
None
0.88A 1z11A-4euuA:
undetectable
1z11A-4euuA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdw LEUCINE RICH
HYPOTHETICAL PROTEIN


(Bacteroides
ovatus)
PF07523
(Big_3)
PF13306
(LRR_5)
5 VAL A 151
ASN A 170
ILE A 138
LEU A 135
PHE A 159
None
0.85A 1z11A-4fdwA:
undetectable
1z11A-4fdwA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grc PUTATIVE MEMBRANE
PROTEIN


(Streptomyces
coelicolor)
PF04261
(Dyp_perox)
5 PHE A 363
VAL A 274
GLY A 373
LEU A 165
PHE A 168
HEM  A 502 (-3.9A)
None
None
None
None
0.82A 1z11A-4grcA:
undetectable
1z11A-4grcA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gs1 DYP-TYPE PEROXIDASE

(Thermobifida
cellulosilytica)
PF04261
(Dyp_perox)
5 PHE A 373
VAL A 276
GLY A 383
LEU A 165
PHE A 168
HEM  A 501 (-4.0A)
None
None
GOL  A 503 (-3.8A)
None
0.84A 1z11A-4gs1A:
undetectable
1z11A-4gs1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gt2 PUTATIVE
UNCHARACTERIZED
PROTEIN SCO3963


(Streptomyces
coelicolor)
no annotation 5 PHE B 390
VAL B 290
GLY B 400
LEU B 177
PHE B 180
HEM  B 501 (-3.9A)
None
None
None
None
0.83A 1z11A-4gt2B:
undetectable
1z11A-4gt2B:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kys THIAMINE
PYRIDINYLASE I


(Clostridium
botulinum)
PF01547
(SBP_bac_1)
5 PHE A  91
PHE A  93
GLY A 105
ILE A 131
LEU A  98
None
1.02A 1z11A-4kysA:
undetectable
1z11A-4kysA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgi UNCHARACTERIZED
PROTEIN


(Escherichia
coli)
PF13678
(Peptidase_M85)
5 VAL A  94
PHE A  90
ILE A 108
GLY A 106
LEU A  84
None
0.97A 1z11A-4lgiA:
undetectable
1z11A-4lgiA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4li3 CYSTEINE SYNTHASE

(Haemophilus
influenzae)
PF00291
(PALP)
5 VAL X 109
ILE X  75
GLY X  74
THR X  69
LEU X 111
None
1.03A 1z11A-4li3X:
undetectable
1z11A-4li3X:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mn8 LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 VAL A 693
ILE A 689
ILE A 641
LEU A 669
PHE A 680
None
1.06A 1z11A-4mn8A:
undetectable
1z11A-4mn8A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mna LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 VAL A 693
ILE A 689
ILE A 641
LEU A 669
PHE A 680
None
1.05A 1z11A-4mnaA:
undetectable
1z11A-4mnaA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o2i NON-LEE ENCODED TYPE
III EFFECTOR C


(Citrobacter
rodentium)
PF13678
(Peptidase_M85)
5 VAL A  94
PHE A  90
ILE A 108
GLY A 106
LEU A  84
None
0.94A 1z11A-4o2iA:
undetectable
1z11A-4o2iA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4odw A6 FAB (IGG2B) HEAVY
CHAIN


(Mus musculus)
no annotation 6 PHE H  29
ASN H  73
GLY H  54
THR H  57
ILE H  69
LEU H  78
None
1.38A 1z11A-4odwH:
undetectable
1z11A-4odwH:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0v FE-HYDROGENASE

(Chlamydomonas
reinhardtii)
PF02256
(Fe_hyd_SSU)
PF02906
(Fe_hyd_lg_C)
5 PHE A 124
ILE A 252
THR A 254
ILE A  99
LEU A 115
None
1.02A 1z11A-4r0vA:
undetectable
1z11A-4r0vA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r72 ABC-TYPE FE3+
TRANSPORT SYSTEM,
PERIPLASMIC
COMPONENT


(Actinobacillus
pleuropneumoniae)
PF13343
(SBP_bac_6)
6 PHE A 295
ILE A 291
GLY A 227
ILE A 104
LEU A 230
PHE A  88
None
1.44A 1z11A-4r72A:
undetectable
1z11A-4r72A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r90 ANTI CD70 LLAMA
GLAMA FAB 27B3 HEAVY
CHAIN


(Lama glama)
PF07654
(C1-set)
PF07686
(V-set)
6 PHE H  29
ASN H  74
GLY H  55
THR H  58
ILE H  70
LEU H  79
None
1.44A 1z11A-4r90H:
undetectable
1z11A-4r90H:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkz PUTATIVE
UNCHARACTERIZED
PROTEIN TA1305


(Thermoplasma
acidophilum)
no annotation 6 PHE A  89
VAL A  94
PHE A  85
ILE A   6
THR A  50
LEU A  78
None
1.43A 1z11A-4rkzA:
undetectable
1z11A-4rkzA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tx8 PROBABLE CHITINASE A

(Chromobacterium
violaceum)
PF00704
(Glyco_hydro_18)
5 ILE A 182
GLY A 181
THR A 184
ILE A 222
LEU A 218
None
0.93A 1z11A-4tx8A:
undetectable
1z11A-4tx8A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udn PERIPLASMIC SOLUTE
BINDING PROTEIN


(Candidatus
Liberibacter
asiaticus)
PF01297
(ZnuA)
5 VAL A   7
ILE A  14
GLY A  15
ILE A  21
LEU A 125
None
0.89A 1z11A-4udnA:
undetectable
1z11A-4udnA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uu9 MEDI7814

(Homo sapiens)
PF07686
(V-set)
6 PHE A  29
ASN A  73
GLY A  54
THR A  57
ILE A  69
LEU A  78
None
1.46A 1z11A-4uu9A:
undetectable
1z11A-4uu9A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w7g DYNEIN LIGHT
INTERMEDIATE CHAIN


(Chaetomium
thermophilum)
PF05783
(DLIC)
5 VAL A 166
ILE A 129
THR A 138
ILE A 140
LEU A 163
None
1.02A 1z11A-4w7gA:
undetectable
1z11A-4w7gA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4weu ANTI-F4+ETEC
BACTERIA VHH
VARIABLE REGION


(Lama glama)
PF07686
(V-set)
6 PHE D 829
ASN D 874
GLY D 855
THR D 858
ILE D 870
LEU D 879
None
1.44A 1z11A-4weuD:
undetectable
1z11A-4weuD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj1 UNCHARACTERIZED
PROTEIN


(Trypanosoma
brucei)
PF09818
(ABC_ATPase)
5 VAL A 256
PHE A 280
THR A 309
ILE A 311
LEU A 322
None
0.94A 1z11A-4yj1A:
undetectable
1z11A-4yj1A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywo MERCURIC REDUCTASE

(Metallosphaera
sedula)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
5 VAL A  99
ILE A   6
ILE A  35
LEU A  94
PHE A  14
None
1.00A 1z11A-4ywoA:
undetectable
1z11A-4ywoA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE


(Moraxella
catarrhalis)
PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C)
5 VAL A 101
ILE A  17
GLY A  18
ILE A  24
LEU A 287
None
NAD  A 501 (-3.9A)
None
None
None
1.01A 1z11A-4zqgA:
undetectable
1z11A-4zqgA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aw4 NA+,K+-ATPASE BETA
SUBUNIT


(Squalus
acanthias)
PF00287
(Na_K-ATPase)
5 PHE B 187
ASN B 284
ILE B 285
GLY B 282
LEU B 242
None
0.94A 1z11A-5aw4B:
undetectable
1z11A-5aw4B:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3n ANTI-H4K20ME1_SCFV

(Mus musculus)
PF07686
(V-set)
6 PHE A  31
ASN A  76
GLY A  57
THR A  60
ILE A  72
LEU A  81
None
1.40A 1z11A-5b3nA:
undetectable
1z11A-5b3nA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c6u AMINOTRANSFERASE

(Mycobacterium
tuberculosis)
PF12897
(Aminotran_MocR)
5 PHE A 216
PHE A 252
ILE A 107
ILE A 151
PHE A 132
None
1.03A 1z11A-5c6uA:
undetectable
1z11A-5c6uA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6a PREDICTED ATPASE OF
THE ABC CLASS


(Vibrio
vulnificus)
PF09818
(ABC_ATPase)
5 VAL A 186
PHE A 209
THR A 237
ILE A 239
LEU A 250
None
0.98A 1z11A-5d6aA:
undetectable
1z11A-5d6aA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5do2 4C2 HEAVY CHAIN

(Mus musculus)
no annotation 6 PHE H  29
ASN H  74
GLY H  55
THR H  58
ILE H  70
LEU H  79
None
1.33A 1z11A-5do2H:
undetectable
1z11A-5do2H:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz TUBULIN GAMMA CHAIN

(Saccharomyces
cerevisiae)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
5 PHE C 204
VAL C  17
ILE C 234
THR C 239
LEU C 139
None
1.04A 1z11A-5flzC:
undetectable
1z11A-5flzC:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078


(Thermobifida
fusca)
PF04261
(Dyp_perox)
5 PHE A 336
VAL A 239
GLY A 346
LEU A 128
PHE A 131
HEM  A 401 ( 4.0A)
None
None
None
None
0.84A 1z11A-5fw4A:
undetectable
1z11A-5fw4A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4e BETA 1-3 GLUCANASE

(Clostridium
beijerinckii)
no annotation 5 VAL A 473
ILE A 491
GLY A 493
ILE A 448
PHE A 525
None
1.02A 1z11A-5h4eA:
undetectable
1z11A-5h4eA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
5 PHE B 758
ILE B1055
GLY B1054
ILE A 670
LEU A 805
None
0.87A 1z11A-5ip9B:
undetectable
1z11A-5ip9B:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ja9 NANOBODY 6

(Lama glama)
PF07686
(V-set)
6 PHE A  30
ASN A  75
GLY A  56
THR A  59
ILE A  71
LEU A  80
None
1.39A 1z11A-5ja9A:
undetectable
1z11A-5ja9A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jmo CAMELID VHH FRAGMENT

(Camelus
dromedarius)
PF07686
(V-set)
6 PHE C  29
ASN C  74
GLY C  55
THR C  58
ILE C  70
LEU C  79
None
1.41A 1z11A-5jmoC:
undetectable
1z11A-5jmoC:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5map DTPA

(Streptomyces
lividans)
PF04261
(Dyp_perox)
5 PHE A 390
VAL A 290
GLY A 400
LEU A 177
PHE A 180
HEM  A 901 (-3.8A)
None
None
None
None
0.83A 1z11A-5mapA:
undetectable
1z11A-5mapA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vk1 PROTEIN MDM4

(Homo sapiens)
no annotation 5 VAL A  74
PHE A  90
GLY A  57
ILE A  36
LEU A  81
None
1.06A 1z11A-5vk1A:
undetectable
1z11A-5vk1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnw ADENYLATE CYCLASE
EXOY


(Pseudomonas
aeruginosa)
no annotation 5 PHE A 339
PHE A 306
VAL A 333
GLY A  62
ILE A 346
None
1.05A 1z11A-5xnwA:
undetectable
1z11A-5xnwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN


(Electrophorus
electricus)
PF00520
(Ion_trans)
PF06512
(Na_trans_assoc)
5 PHE A 785
ASN A1257
ILE A1260
GLY A1261
LEU A 790
None
0.94A 1z11A-5xsyA:
undetectable
1z11A-5xsyA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9c MAJOR CAPSID PROTEIN
L1


(Alphapapillomavirus
9)
no annotation 5 PHE A 373
PHE A 375
ILE A 160
GLY A 161
LEU A  78
None
0.98A 1z11A-5y9cA:
undetectable
1z11A-5y9cA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN


(Vibrio harveyi)
no annotation 5 VAL A 405
ILE A 481
ILE A 382
LEU A 355
PHE A 269
None
1.05A 1z11A-5yqwA:
undetectable
1z11A-5yqwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d2k FERM, ARHGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 2


(Mus musculus)
no annotation 5 PHE A 309
GLY A 252
ILE A 282
LEU A 273
PHE A 280
None
1.03A 1z11A-6d2kA:
undetectable
1z11A-6d2kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fe4 NB113

(Vicugna pacos)
no annotation 6 PHE F  29
ASN F  74
GLY F  55
THR F  58
ILE F  70
LEU F  79
None
1.46A 1z11A-6fe4F:
undetectable
1z11A-6fe4F:
undetectable