SIMILAR PATTERNS OF AMINO ACIDS FOR 1YHL_A_RISA1400_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

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	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1fps	FARNESYL DIPHOSPHATE SYNTHASE (Gallus gallus)	PF00348 (polyprenyl_synt)	5	LEU A 114 ARG A 126 GLN A 185 LYS A 214 TYR A 218	None	1.11A	1yhlA-1fpsA: 39.0	1yhlA-1fpsA: 37.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1fps	FARNESYL DIPHOSPHATE SYNTHASE (Gallus gallus)	PF00348 (polyprenyl_synt)	5	LEU A 114 ARG A 126 LYS A 214 THR A 215 TYR A 218	None	0.93A	1yhlA-1fpsA: 39.0	1yhlA-1fpsA: 37.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1fps	FARNESYL DIPHOSPHATE SYNTHASE (Gallus gallus)	PF00348 (polyprenyl_synt)	5	LEU A 114 ARG A 126 THR A 215 TYR A 218 GLN A 254	None	0.85A	1yhlA-1fpsA: 39.0	1yhlA-1fpsA: 37.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1fps	FARNESYL DIPHOSPHATE SYNTHASE (Gallus gallus)	PF00348 (polyprenyl_synt)	5	LEU A 114 ASP A 117 ARG A 126 GLN A 185 TYR A 218	None	0.93A	1yhlA-1fpsA: 39.0	1yhlA-1fpsA: 37.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1fps	FARNESYL DIPHOSPHATE SYNTHASE (Gallus gallus)	PF00348 (polyprenyl_synt)	5	LEU A 114 ASP A 117 ARG A 126 THR A 215 TYR A 218	None	0.68A	1yhlA-1fpsA: 39.0	1yhlA-1fpsA: 37.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rqj	GERANYLTRANSTRANSFER ASE (Escherichia coli)	PF00348 (polyprenyl_synt)	10	LEU A 102 ASP A 105 ASP A 111 ARG A 116 GLN A 179 LYS A 202 THR A 203 GLN A 241 ASP A 244 LYS A 258	None MG A 907 (-2.5A) MG A 909 (-2.4A) RIS A 901 (-2.7A) RIS A 901 (-3.2A) RIS A 901 (-2.5A) IPE A 900 ( 3.3A) RIS A 901 ( 3.6A) MG A 908 ( 2.7A) RIS A 901 (-2.7A)	0.31A	1yhlA-1rqjA: 31.1	1yhlA-1rqjA: 25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rtr	GERANYLTRANSTRANSFER ASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ASP A 88 ARG A 93 THR A 178 GLN A 215	None	0.81A	1yhlA-1rtrA: 25.0	1yhlA-1rtrA: 27.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1wmw	GERANYLGERANYL DIPHOSPHATE SYNTHETASE (Thermus thermophilus)	PF00348 (polyprenyl_synt)	5	LEU A 76 ARG A 88 TYR A 176 GLN A 209 ASP A 212	None	0.97A	1yhlA-1wmwA: 32.4	1yhlA-1wmwA: 27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1wmw	GERANYLGERANYL DIPHOSPHATE SYNTHETASE (Thermus thermophilus)	PF00348 (polyprenyl_synt)	6	LEU A 76 ASP A 79 ASP A 83 ARG A 88 GLN A 146 GLN A 209	None	1.36A	1yhlA-1wmwA: 32.4	1yhlA-1wmwA: 27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1wmw	GERANYLGERANYL DIPHOSPHATE SYNTHETASE (Thermus thermophilus)	PF00348 (polyprenyl_synt)	6	LEU A 76 ASP A 79 ASP A 83 ARG A 88 TYR A 176 GLN A 209	None	0.98A	1yhlA-1wmwA: 32.4	1yhlA-1wmwA: 27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1wy0	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Pyrococcus horikoshii)	PF00348 (polyprenyl_synt)	5	LEU A 83 ASP A 90 ARG A 95 THR A 178 GLN A 215	None	0.62A	1yhlA-1wy0A: 29.1	1yhlA-1wy0A: 26.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	6	ASP A 85 ARG A 90 LYS A 160 THR A 161 GLN A 197 ASP A 200	None	1.38A	1yhlA-2azkA: 24.5	1yhlA-2azkA: 26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	5	LEU A 78 ASP A 81 ARG A 90 THR A 161 GLN A 197	None	0.95A	1yhlA-2azkA: 24.5	1yhlA-2azkA: 26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	6	LEU A 78 ASP A 85 ARG A 90 THR A 161 GLN A 197 ASP A 200	None	0.84A	1yhlA-2azkA: 24.5	1yhlA-2azkA: 26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2dh4	YPL069C (Saccharomyces cerevisiae)	PF00348 (polyprenyl_synt)	9	LEU A 77 ASP A 80 ASP A 84 ARG A 89 GLN A 147 LYS A 174 THR A 175 GLN A 211 ASP A 214	None MG A 341 (-2.6A) MG A 341 (-3.0A) MG A 341 ( 4.6A) None None None None None	0.65A	1yhlA-2dh4A: 26.4	1yhlA-2dh4A: 22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ftz	GERANYLTRANSTRANSFER ASE (Thermotoga maritima)	PF00348 (polyprenyl_synt)	5	LEU A 71 ASP A 74 ARG A 85 THR A 164 GLN A 198	None UNL A 273 (-3.0A) UNL A 274 (-4.1A) MLY A 163 ( 3.9A) MLY A 163 ( 3.8A)	0.83A	1yhlA-2ftzA: 24.9	1yhlA-2ftzA: 25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ftz	GERANYLTRANSTRANSFER ASE (Thermotoga maritima)	PF00348 (polyprenyl_synt)	5	LEU A 71 ASP A 80 ARG A 85 THR A 164 GLN A 198	None MLY A 223 ( 3.6A) UNL A 274 (-4.1A) MLY A 163 ( 3.9A) MLY A 163 ( 3.8A)	0.53A	1yhlA-2ftzA: 24.9	1yhlA-2ftzA: 25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2o1o	PUTATIVE FARNESYL PYROPHOSPHATE SYNTHASE (Cryptosporidium parvum)	PF00348 (polyprenyl_synt)	9	LEU A 112 ASP A 115 ASP A 119 ARG A 124 GLN A 184 LYS A 210 THR A 211 TYR A 214 GLN A 251	None MG A 503 (-2.5A) MG A 502 (-2.4A) RIS A 400 (-2.9A) RIS A 400 ( 3.5A) RIS A 400 (-2.8A) RIS A 400 (-3.7A) None RIS A 400 (-3.1A)	0.42A	1yhlA-2o1oA: 36.8	1yhlA-2o1oA: 27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	PF00348 (polyprenyl_synt)	6	LEU A 61 ARG A 73 GLN A 126 LYS A 151 GLN A 185 LYS A 202	None GRG A 500 (-2.9A) GRG A 500 ( 3.5A) GRG A 500 (-2.8A) GRG A 500 (-3.2A) GRG A 500 ( 2.6A)	1.27A	1yhlA-2q80A: 25.7	1yhlA-2q80A: 25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	PF00348 (polyprenyl_synt)	8	LEU A 61 ASP A 64 ASP A 68 ARG A 73 GLN A 126 LYS A 151 GLN A 185 ASP A 188	None GRG A 500 (-2.4A) MG A 400 (-2.6A) GRG A 500 (-2.9A) GRG A 500 ( 3.5A) GRG A 500 (-2.8A) GRG A 500 (-3.2A) GRG A 500 (-3.5A)	0.62A	1yhlA-2q80A: 25.7	1yhlA-2q80A: 25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3aq0	GERANYL DIPHOSPHATE SYNTHASE (Arabidopsis thaliana)	PF00348 (polyprenyl_synt)	6	LEU A 104 ASP A 107 ASP A 111 ARG A 116 LYS A 193 THR A 194	None MG A1000 (-2.9A) MG A1001 (-2.8A) FPP A1002 (-2.9A) FPP A1002 (-2.5A) ISY A1003 (-4.7A)	0.71A	1yhlA-3aq0A: 23.8	1yhlA-3aq0A: 25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3aqc	COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE (Micrococcus luteus)	PF00348 (polyprenyl_synt)	7	ASP B 84 ASP B 88 ARG B 93 LYS B 170 THR B 171 GLN B 208 ASP B 211	MG B 326 (-2.6A) MG B 327 (-2.4A) 2DE B 329 (-3.8A) 2DE B 329 (-2.5A) None None MG B 328 (-3.1A)	1.03A	1yhlA-3aqcB: 28.2	1yhlA-3aqcB: 27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3aqc	COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE (Micrococcus luteus)	PF00348 (polyprenyl_synt)	7	LEU B 81 ASP B 84 ASP B 88 ARG B 93 LYS B 170 THR B 171 GLN B 208	None MG B 326 (-2.6A) MG B 327 (-2.4A) 2DE B 329 (-3.8A) 2DE B 329 (-2.5A) None None	0.85A	1yhlA-3aqcB: 28.2	1yhlA-3aqcB: 27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m0g	FARNESYL DIPHOSPHATE SYNTHASE (Rhodobacter capsulatus)	PF00348 (polyprenyl_synt)	5	LEU A 78 ASP A 87 ARG A 92 GLN A 153 LYS A 178	None	0.95A	1yhlA-3m0gA: 24.6	1yhlA-3m0gA: 27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m0g	FARNESYL DIPHOSPHATE SYNTHASE (Rhodobacter capsulatus)	PF00348 (polyprenyl_synt)	5	LEU A 78 ASP A 87 ARG A 92 LYS A 178 THR A 179	None	0.75A	1yhlA-3m0gA: 24.6	1yhlA-3m0gA: 27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m9u	FARNESYL-DIPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 86 ARG A 100 THR A 184 GLN A 221 ASP A 224	GOL A 310 ( 4.3A) None None None None	0.86A	1yhlA-3m9uA: 25.0	1yhlA-3m9uA: 24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mzv	DECAPRENYL DIPHOSPHATE SYNTHASE (Rhodobacter capsulatus)	PF00348 (polyprenyl_synt)	6	LEU A 90 ASP A 93 ARG A 102 LYS A 179 THR A 180 GLN A 217	None	0.79A	1yhlA-3mzvA: 25.4	1yhlA-3mzvA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3npk	GERANYLTRANSTRANSFER ASE (Campylobacter jejuni)	PF00348 (polyprenyl_synt)	5	LEU A 75 ASP A 78 ARG A 89 LYS A 172 THR A 173	None	1.05A	1yhlA-3npkA: 26.1	1yhlA-3npkA: 23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3npk	GERANYLTRANSTRANSFER ASE (Campylobacter jejuni)	PF00348 (polyprenyl_synt)	5	LEU A 75 ASP A 84 ARG A 89 LYS A 172 THR A 173	None	0.84A	1yhlA-3npkA: 26.1	1yhlA-3npkA: 23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3p41	GERANYLTRANSTRANSFER ASE (Pseudomonas protegens)	PF00348 (polyprenyl_synt)	7	LEU A 80 ASP A 83 ASP A 89 ARG A 94 GLN A 157 LYS A 180 THR A 181	None MG A 297 (-2.5A) MG A 297 (-2.5A) DMA A 300 (-2.9A) DMA A 300 (-3.6A) POP A 301 ( 2.4A) None	0.52A	1yhlA-3p41A: 24.4	1yhlA-3p41A: 27.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pko	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 84 ASP A 87 ARG A 96 LYS A 174 THR A 175	None None CIT A 326 ( 4.8A) None None	0.96A	1yhlA-3pkoA: 25.5	1yhlA-3pkoA: 23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pko	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 84 ASP A 91 ARG A 96 LYS A 174 THR A 175	None None CIT A 326 ( 4.8A) None None	0.97A	1yhlA-3pkoA: 25.5	1yhlA-3pkoA: 23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3q1o	GERANYLTRANSTRANSFER ASE (ISPA) (Helicobacter pylori)	PF00348 (polyprenyl_synt)	10	LEU A 89 ASP A 92 ASP A 98 ARG A 103 GLN A 163 LYS A 186 THR A 187 GLN A 225 ASP A 228 LYS A 242	DMA A 501 ( 4.8A) MG A 400 ( 2.8A) MG A 400 ( 3.2A) DMA A 501 (-3.0A) DMA A 501 (-3.6A) DMA A 501 (-3.1A) DMA A 500 (-3.4A) DMA A 501 ( 3.8A) DMA A 501 ( 3.5A) DMA A 501 (-2.7A)	0.50A	1yhlA-3q1oA: 30.3	1yhlA-3q1oA: 23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qqv	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Corynebacterium glutamicum)	PF00348 (polyprenyl_synt)	6	LEU A 105 ASP A 108 ARG A 117 GLN A 191 LYS A 215 LYS A 271	None MG A 381 (-2.4A) DMA A 384 (-3.0A) DMA A 384 (-3.9A) DMA A 384 (-3.0A) DMA A 384 ( 2.8A)	1.37A	1yhlA-3qqvA: 33.6	1yhlA-3qqvA: 26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qqv	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Corynebacterium glutamicum)	PF00348 (polyprenyl_synt)	6	LEU A 105 ASP A 108 ARG A 117 GLN A 191 LYS A 215 TYR A 219	None MG A 381 (-2.4A) DMA A 384 (-3.0A) DMA A 384 (-3.9A) DMA A 384 (-3.0A) DMA A 384 ( 4.9A)	1.05A	1yhlA-3qqvA: 33.6	1yhlA-3qqvA: 26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qqv	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Corynebacterium glutamicum)	PF00348 (polyprenyl_synt)	6	LEU A 105 ASP A 108 ASP A 112 ARG A 117 GLN A 191 LYS A 215	None MG A 381 (-2.4A) MG A 381 (-2.8A) DMA A 384 (-3.0A) DMA A 384 (-3.9A) DMA A 384 (-3.0A)	0.77A	1yhlA-3qqvA: 33.6	1yhlA-3qqvA: 26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qqv	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Corynebacterium glutamicum)	PF00348 (polyprenyl_synt)	7	LEU A 105 ASP A 108 ASP A 112 ARG A 117 LYS A 215 THR A 216 GLN A 254	None MG A 381 (-2.4A) MG A 381 (-2.8A) DMA A 384 (-3.0A) DMA A 384 (-3.0A) DMA A 383 ( 4.0A) DMA A 383 (-3.2A)	0.61A	1yhlA-3qqvA: 33.6	1yhlA-3qqvA: 26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3tc1	OCTAPRENYL PYROPHOSPHATE SYNTHASE (Helicobacter pylori)	PF00348 (polyprenyl_synt)	5	LEU A 74 ASP A 77 LYS A 162 THR A 163 GLN A 197	None	0.73A	1yhlA-3tc1A: 25.1	1yhlA-3tc1A: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3tc1	OCTAPRENYL PYROPHOSPHATE SYNTHASE (Helicobacter pylori)	PF00348 (polyprenyl_synt)	5	LEU A 74 LYS A 162 THR A 163 GLN A 197 ASP A 200	None None None None MG A 500 (-2.9A)	0.47A	1yhlA-3tc1A: 25.1	1yhlA-3tc1A: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ts7	GERANYLTRANSTRANSFER ASE (Methylococcus capsulatus)	PF00348 (polyprenyl_synt)	5	LEU A 85 ASP A 88 ASP A 94 LYS A 185 THR A 186	None	1.13A	1yhlA-3ts7A: 24.9	1yhlA-3ts7A: 26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ts7	GERANYLTRANSTRANSFER ASE (Methylococcus capsulatus)	PF00348 (polyprenyl_synt)	5	LEU A 85 ASP A 94 ARG A 99 LYS A 185 THR A 186	None	0.78A	1yhlA-3ts7A: 24.9	1yhlA-3ts7A: 26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wjo	OCTAPRENYL DIPHOSPHATE SYNTHASE (Escherichia coli)	PF00348 (polyprenyl_synt)	6	LEU A 81 ARG A 93 LYS A 170 THR A 171 GLN A 208 ASP A 211	None IPE A 401 ( 4.2A) IPE A 401 ( 2.9A) IPE A 402 ( 3.8A) IPE A 402 (-3.6A) IPE A 402 ( 4.6A)	0.91A	1yhlA-3wjoA: 25.2	1yhlA-3wjoA: 26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wjo	OCTAPRENYL DIPHOSPHATE SYNTHASE (Escherichia coli)	PF00348 (polyprenyl_synt)	6	LEU A 81 ASP A 84 ARG A 93 LYS A 170 THR A 171 GLN A 208	None IPE A 401 (-2.6A) IPE A 401 ( 4.2A) IPE A 401 ( 2.9A) IPE A 402 ( 3.8A) IPE A 402 (-3.6A)	0.88A	1yhlA-3wjoA: 25.2	1yhlA-3wjoA: 26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wjo	OCTAPRENYL DIPHOSPHATE SYNTHASE (Escherichia coli)	PF00348 (polyprenyl_synt)	6	LEU A 81 ASP A 84 ASP A 88 ARG A 93 LYS A 170 THR A 171	None IPE A 401 (-2.6A) IPE A 401 (-3.3A) IPE A 401 ( 4.2A) IPE A 401 ( 2.9A) IPE A 402 ( 3.8A)	0.89A	1yhlA-3wjoA: 25.2	1yhlA-3wjoA: 26.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zou	FARNESYL PYROPHOSPHATE SYNTHASE (Pseudomonas aeruginosa)	PF00348 (polyprenyl_synt)	5	LEU A 80 ASP A 83 ASP A 89 ARG A 94 GLN A 157	None MG A1295 (-2.5A) MG A1295 (-2.4A) GPP A1297 (-3.0A) GPP A1297 (-3.7A)	0.45A	1yhlA-3zouA: 24.1	1yhlA-3zouA: 25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zou	FARNESYL PYROPHOSPHATE SYNTHASE (Pseudomonas aeruginosa)	PF00348 (polyprenyl_synt)	6	LEU A 80 ASP A 83 ASP A 89 ARG A 94 LYS A 180 THR A 181	None MG A1295 (-2.5A) MG A1295 (-2.4A) GPP A1297 (-3.0A) GPP A1297 (-3.0A) None	0.57A	1yhlA-3zouA: 24.1	1yhlA-3zouA: 25.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4e1e	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma cruzi)	PF00348 (polyprenyl_synt)	11	LEU A 95 ASP A 98 ASP A 102 ARG A 107 GLN A 167 LYS A 207 THR A 208 TYR A 211 GLN A 247 ASP A 250 LYS A 264	None MG A 403 (-2.5A) MG A 403 (-2.4A) 0MW A 404 (-2.7A) 0MW A 404 (-3.7A) 0MW A 404 (-2.8A) IPE A 405 ( 4.6A) None 0MW A 404 ( 3.8A) MG A 401 (-2.7A) 0MW A 404 ( 3.0A)	0.46A	1yhlA-4e1eA: 57.0	1yhlA-4e1eA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4f62	GERANYLTRANSTRANSFER ASE (Marinomonas sp. MED121)	PF00348 (polyprenyl_synt)	5	LEU A 80 ASP A 83 ASP A 89 LYS A 178 THR A 179	None	0.88A	1yhlA-4f62A: 24.0	1yhlA-4f62A: 27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4f62	GERANYLTRANSTRANSFER ASE (Marinomonas sp. MED121)	PF00348 (polyprenyl_synt)	5	LEU A 80 ASP A 83 GLN A 155 LYS A 178 THR A 179	None	1.07A	1yhlA-4f62A: 24.0	1yhlA-4f62A: 27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fp4	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	5	ASP A 86 ASP A 90 ARG A 95 GLN A 147 GLN A 199	UNX A 302 ( 2.6A) UNX A 302 ( 3.2A) UNX A 302 ( 4.6A) GER A 301 ( 4.7A) None	1.05A	1yhlA-4fp4A: 21.2	1yhlA-4fp4A: 23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fp4	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	5	ASP A 86 ASP A 90 ARG A 95 THR A 163 GLN A 199	UNX A 302 ( 2.6A) UNX A 302 ( 3.2A) UNX A 302 ( 4.6A) None None	0.78A	1yhlA-4fp4A: 21.2	1yhlA-4fp4A: 23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fp4	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	6	LEU A 83 ASP A 86 ASP A 90 ARG A 95 LYS A 162 THR A 163	UNL A 303 ( 4.7A) UNX A 302 ( 2.6A) UNX A 302 ( 3.2A) UNX A 302 ( 4.6A) GER A 301 ( 4.8A) None	1.05A	1yhlA-4fp4A: 21.2	1yhlA-4fp4A: 23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4gp1	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	5	LEU A 82 ASP A 85 ARG A 94 LYS A 184 THR A 185	None	0.95A	1yhlA-4gp1A: 28.4	1yhlA-4gp1A: 26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4gp1	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	5	LEU A 82 ASP A 85 ASP A 89 ARG A 94 LYS A 184	None	0.90A	1yhlA-4gp1A: 28.4	1yhlA-4gp1A: 26.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4jxy	TRANS-HEXAPRENYLTRAN STRANSFERASE (Pseudoalteromonas atlantica)	PF00348 (polyprenyl_synt)	5	LEU A 81 ASP A 84 LYS A 170 THR A 171 GLN A 208	None	0.89A	1yhlA-4jxyA: 24.9	1yhlA-4jxyA: 25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4jxy	TRANS-HEXAPRENYLTRAN STRANSFERASE (Pseudoalteromonas atlantica)	PF00348 (polyprenyl_synt)	5	LEU A 81 LYS A 170 THR A 171 GLN A 208 ASP A 211	None	0.82A	1yhlA-4jxyA: 24.9	1yhlA-4jxyA: 25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4jzx	FARNESYL PYROPHOSPHATE SYNTHASE (Leishmania major)	PF00348 (polyprenyl_synt)	5	ASP A 98 ARG A 107 GLN A 247 ASP A 250 LYS A 264	CA A 403 (-2.5A) 476 A 402 (-2.9A) IPE A 401 (-3.7A) CA A 404 (-3.0A) 476 A 402 (-2.9A)	1.13A	1yhlA-4jzxA: 54.0	1yhlA-4jzxA: 63.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4jzx	FARNESYL PYROPHOSPHATE SYNTHASE (Leishmania major)	PF00348 (polyprenyl_synt)	8	LEU A 95 ASP A 98 ASP A 102 ARG A 107 GLN A 167 GLN A 247 ASP A 250 LYS A 264	None CA A 403 (-2.5A) CA A 403 (-2.5A) 476 A 402 (-2.9A) 476 A 402 (-3.5A) IPE A 401 (-3.7A) CA A 404 (-3.0A) 476 A 402 (-2.9A)	0.63A	1yhlA-4jzxA: 54.0	1yhlA-4jzxA: 63.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4jzx	FARNESYL PYROPHOSPHATE SYNTHASE (Leishmania major)	PF00348 (polyprenyl_synt)	10	LEU A 95 ASP A 98 ASP A 102 ARG A 107 LYS A 207 THR A 208 TYR A 211 GLN A 247 ASP A 250 LYS A 264	None CA A 403 (-2.5A) CA A 403 (-2.5A) 476 A 402 (-2.9A) 476 A 402 (-2.7A) IPE A 401 ( 3.4A) None IPE A 401 (-3.7A) CA A 404 (-3.0A) 476 A 402 (-2.9A)	0.44A	1yhlA-4jzxA: 54.0	1yhlA-4jzxA: 63.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4kk2	MONOTERPENE SYNTHASE FDS-5, CHLOROPLASTIC - FARNESYL DIPHOSPHATE SYNTHASE 1 CHIMERA (Artemisia spiciformis)	PF00348 (polyprenyl_synt)	6	LEU A 94 ASP A 97 ARG A 106 LYS A 194 THR A 195 TYR A 198	None	1.00A	1yhlA-4kk2A: 40.5	1yhlA-4kk2A: 38.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4kkm	POLYPRENYL SYNTHETASE (Zymomonas mobilis)	PF00348 (polyprenyl_synt)	6	LEU A 83 ASP A 86 ASP A 92 ARG A 97 GLN A 159 THR A 185	None	0.67A	1yhlA-4kkmA: 25.0	1yhlA-4kkmA: 25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4kkm	POLYPRENYL SYNTHETASE (Zymomonas mobilis)	PF00348 (polyprenyl_synt)	5	LEU A 83 ASP A 92 ARG A 97 LYS A 184 THR A 185	None	1.16A	1yhlA-4kkmA: 25.0	1yhlA-4kkmA: 25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lfe	GERANYLGERANYL DIPHOSPHATE SYNTHASE (Streptococcus uberis)	PF00348 (polyprenyl_synt)	7	LEU A 75 ARG A 89 GLN A 149 LYS A 172 THR A 173 GLN A 210 ASP A 213	IPE A 301 (-4.7A) IPE A 301 (-2.8A) IPE A 301 ( 3.7A) IPE A 301 (-3.0A) None None None	0.88A	1yhlA-4lfeA: 25.9	1yhlA-4lfeA: 24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lfe	GERANYLGERANYL DIPHOSPHATE SYNTHASE (Streptococcus uberis)	PF00348 (polyprenyl_synt)	8	LEU A 75 ASP A 78 ASP A 84 ARG A 89 GLN A 149 LYS A 172 THR A 173 GLN A 210	IPE A 301 (-4.7A) MG A 302 (-2.5A) MG A 302 (-2.4A) IPE A 301 (-2.8A) IPE A 301 ( 3.7A) IPE A 301 (-3.0A) None None	0.69A	1yhlA-4lfeA: 25.9	1yhlA-4lfeA: 24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lls	GERANYLTRANSTRANSFER ASE (Roseobacter denitrificans)	PF00348 (polyprenyl_synt)	7	LEU A 77 ASP A 80 ASP A 86 ARG A 91 GLN A 153 ASP A 216 LYS A 230	None CA A 304 ( 2.9A) CA A 305 (-2.3A) GST A 302 (-2.9A) GST A 302 (-3.7A) CA A 303 (-2.9A) GST A 302 (-2.7A)	0.75A	1yhlA-4llsA: 28.9	1yhlA-4llsA: 26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lls	GERANYLTRANSTRANSFER ASE (Roseobacter denitrificans)	PF00348 (polyprenyl_synt)	8	LEU A 77 ASP A 80 ASP A 86 ARG A 91 LYS A 178 THR A 179 ASP A 216 LYS A 230	None CA A 304 ( 2.9A) CA A 305 (-2.3A) GST A 302 (-2.9A) GST A 302 (-3.4A) IPE A 301 (-4.2A) CA A 303 (-2.9A) GST A 302 (-2.7A)	0.62A	1yhlA-4llsA: 28.9	1yhlA-4llsA: 26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lls	GERANYLTRANSTRANSFER ASE (Roseobacter denitrificans)	PF00348 (polyprenyl_synt)	8	LEU A 77 ASP A 80 ASP A 86 ARG A 91 THR A 179 GLN A 213 ASP A 216 LYS A 230	None CA A 304 ( 2.9A) CA A 305 (-2.3A) GST A 302 (-2.9A) IPE A 301 (-4.2A) IPE A 301 ( 4.1A) CA A 303 (-2.9A) GST A 302 (-2.7A)	0.58A	1yhlA-4llsA: 28.9	1yhlA-4llsA: 26.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lob	POLYPRENYL SYNTHETASE (Acinetobacter baumannii)	PF00348 (polyprenyl_synt)	5	LEU A 85 ASP A 88 LYS A 174 THR A 175 GLN A 211	None	0.88A	1yhlA-4lobA: 26.4	1yhlA-4lobA: 25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lob	POLYPRENYL SYNTHETASE (Acinetobacter baumannii)	PF00348 (polyprenyl_synt)	5	LEU A 85 LYS A 174 THR A 175 GLN A 211 ASP A 214	None	0.87A	1yhlA-4lobA: 26.4	1yhlA-4lobA: 25.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	PF00348 (polyprenyl_synt)	11	LEU A 100 ASP A 103 ASP A 107 ARG A 112 GLN A 171 LYS A 200 THR A 201 TYR A 204 GLN A 240 ASP A 243 LYS A 257	None MG A 405 (-2.5A) MG A 405 (-2.4A) ZOL A 401 ( 2.7A) ZOL A 401 ( 3.8A) ZOL A 401 (-2.7A) ZOL A 401 (-3.7A) None ZOL A 401 (-3.5A) MG A 404 (-2.8A) 1WO A 402 ( 2.8A)	0.30A	1yhlA-4p0vA: 45.8	1yhlA-4p0vA: 37.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4rxe	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma brucei)	PF00348 (polyprenyl_synt)	9	ASP A 103 ASP A 107 ARG A 112 GLN A 172 LYS A 212 THR A 213 GLN A 252 ASP A 255 LYS A 269	MG A3004 (-2.5A) MG A3004 (-2.3A) 3YQ A3001 (-2.8A) MG A3004 ( 3.8A) 3YQ A3001 (-2.9A) 3YQ A3001 (-4.2A) 3YQ A3001 ( 4.2A) MG A3003 ( 2.9A) 3YQ A3001 (-3.1A)	0.78A	1yhlA-4rxeA: 52.9	1yhlA-4rxeA: 66.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4rxe	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma brucei)	PF00348 (polyprenyl_synt)	9	ASP A 103 ASP A 107 ARG A 112 GLN A 172 LYS A 212 THR A 213 TYR A 216 GLN A 252 ASP A 255	MG A3004 (-2.5A) MG A3004 (-2.3A) 3YQ A3001 (-2.8A) MG A3004 ( 3.8A) 3YQ A3001 (-2.9A) 3YQ A3001 (-4.2A) 3YQ A3001 (-4.7A) 3YQ A3001 ( 4.2A) MG A3003 ( 2.9A)	0.30A	1yhlA-4rxeA: 52.9	1yhlA-4rxeA: 66.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4rxe	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma brucei)	PF00348 (polyprenyl_synt)	8	LEU A 100 ASP A 103 ASP A 107 ARG A 112 GLN A 172 LYS A 212 TYR A 216 ASP A 255	3YQ A3001 ( 4.6A) MG A3004 (-2.5A) MG A3004 (-2.3A) 3YQ A3001 (-2.8A) MG A3004 ( 3.8A) 3YQ A3001 (-2.9A) 3YQ A3001 (-4.7A) MG A3003 ( 2.9A)	0.57A	1yhlA-4rxeA: 52.9	1yhlA-4rxeA: 66.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4wk5	GERANYLTRANSTRANSFER ASE (Thermotoga neapolitana)	PF00348 (polyprenyl_synt)	6	LEU A 71 ASP A 80 ARG A 85 THR A 164 GLN A 198 ASP A 201	None	0.76A	1yhlA-4wk5A: 24.7	1yhlA-4wk5A: 25.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5ahu	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma brucei)	PF00348 (polyprenyl_synt)	11	LEU B 100 ASP B 103 ASP B 107 ARG B 112 GLN B 172 LYS B 212 THR B 213 TYR B 216 GLN B 252 ASP B 255 LYS B 269	None MG B1370 (-2.5A) MG B1369 (-2.2A) G76 B1368 (-2.8A) G76 B1368 ( 4.1A) G76 B1368 (-2.8A) G76 B1368 (-4.2A) None G76 B1368 ( 4.0A) MG B1371 ( 3.0A) G76 B1368 (-3.1A)	0.53A	1yhlA-5ahuB: 39.9	1yhlA-5ahuB: 73.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ayp	FARNESYL DIPHOSPHATE SYNTHASE (Geobacillus stearothermophilus)	PF00348 (polyprenyl_synt)	6	LEU A 83 ASP A 86 ASP A 92 ARG A 97 GLN A 160 THR A 184	None	0.73A	1yhlA-5aypA: 23.9	1yhlA-5aypA: 26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ayp	FARNESYL DIPHOSPHATE SYNTHASE (Geobacillus stearothermophilus)	PF00348 (polyprenyl_synt)	6	LEU A 83 ASP A 92 ARG A 97 GLN A 160 LYS A 183 THR A 184	None	0.94A	1yhlA-5aypA: 23.9	1yhlA-5aypA: 26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e8l	HETERODIMERIC GERANYLGERANYL PYROPHOSPHATE SYNTHASE LARGE SUBUNIT 1, CHLOROPLASTIC (Arabidopsis thaliana)	PF00348 (polyprenyl_synt)	5	LEU A 88 ASP A 91 ASP A 97 ARG A 102 GLN A 166	None	0.97A	1yhlA-5e8lA: 24.0	1yhlA-5e8lA: 25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h9d	FARNESYL PYROPHOSPHATE SYNTHETASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	6	LEU A 79 ASP A 82 ARG A 91 LYS A 168 THR A 169 GLN A 206	PO4 A 501 (-4.5A) None PO4 A 501 ( 4.9A) None None None	0.98A	1yhlA-5h9dA: 28.8	1yhlA-5h9dA: 26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h9d	FARNESYL PYROPHOSPHATE SYNTHETASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ASP A 86 ARG A 91 LYS A 168 THR A 169	PO4 A 501 (-4.5A) None PO4 A 501 ( 4.9A) None None	0.85A	1yhlA-5h9dA: 28.8	1yhlA-5h9dA: 26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h9d	FARNESYL PYROPHOSPHATE SYNTHETASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 LYS A 168 THR A 169 GLN A 206 ASP A 209	PO4 A 501 (-4.5A) None None None None	0.98A	1yhlA-5h9dA: 28.8	1yhlA-5h9dA: 26.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5hn7	FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE (Plasmodium vivax)	PF00348 (polyprenyl_synt)	9	ASP A 126 ASP A 130 ARG A 135 GLN A 195 LYS A 243 TYR A 247 GLN A 284 ASP A 287 LYS A 301	04M A 401 ( 4.0A) None 04M A 401 (-3.5A) 04M A 401 (-3.3A) 04M A 401 (-4.5A) 04M A 401 (-4.5A) None None 04M A 401 ( 3.9A)	0.73A	1yhlA-5hn7A: 43.4	1yhlA-5hn7A: 31.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5hn7	FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE (Plasmodium vivax)	PF00348 (polyprenyl_synt)	9	ASP A 126 ASP A 130 ARG A 135 LYS A 243 THR A 244 TYR A 247 GLN A 284 ASP A 287 LYS A 301	04M A 401 ( 4.0A) None 04M A 401 (-3.5A) 04M A 401 (-4.5A) 04M A 401 ( 3.8A) 04M A 401 (-4.5A) None None 04M A 401 ( 3.9A)	0.57A	1yhlA-5hn7A: 43.4	1yhlA-5hn7A: 31.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6b07	FARNESYL DIPHOSPHATE SYNTHASE (Choristoneura fumiferana)	no annotation	10	ASP A 147 ASP A 151 ARG A 156 GLN A 215 LYS A 244 THR A 245 TYR A 248 GLN A 284 ASP A 287 LYS A 301	MG A 402 (-2.6A) MG A 402 (-2.5A) C6M A 401 (-2.7A) C6M A 401 (-3.3A) C6M A 401 (-2.6A) C6M A 401 (-3.6A) None C6M A 401 (-3.7A) MG A 404 ( 2.7A) C6M A 401 (-2.9A)	0.42A	1yhlA-6b07A: 43.9	1yhlA-6b07A: 12.36

[["1YHL_A_RISA1400_1","1fps","Gallus gallus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A 114;ARG A 126;GLN A 185;LYS A 214;TYR A 218","None","1.11A","1yhlA-1fpsA:39.0","1yhlA-1fpsA:37.53"],["1YHL_A_RISA1400_1","1fps","Gallus gallus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A 114;ARG A 126;LYS A 214;THR A 215;TYR A 218","None","0.93A","1yhlA-1fpsA:39.0","1yhlA-1fpsA:37.53"],["1YHL_A_RISA1400_1","1fps","Gallus gallus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A 114;ARG A 126;THR A 215;TYR A 218;GLN A 254","None","0.85A","1yhlA-1fpsA:39.0","1yhlA-1fpsA:37.53"],["1YHL_A_RISA1400_1","1fps","Gallus gallus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A 114;ASP A 117;ARG A 126;GLN A 185;TYR A 218","None","0.93A","1yhlA-1fpsA:39.0","1yhlA-1fpsA:37.53"],["1YHL_A_RISA1400_1","1fps","Gallus gallus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A 114;ASP A 117;ARG A 126;THR A 215;TYR A 218","None","0.68A","1yhlA-1fpsA:39.0","1yhlA-1fpsA:37.53"],["1YHL_A_RISA1400_1","1rqj","Escherichia coli","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",10,"LEU A 102;ASP A 105;ASP A 111;ARG A 116;GLN A 179;LYS A 202;THR A 203;GLN A 241;ASP A 244;LYS A 258","None; MG A 907 (-2.5A); MG A 909 (-2.4A);RIS A 901 (-2.7A);RIS A 901 (-3.2A);RIS A 901 (-2.5A);IPE A 900 ( 3.3A);RIS A 901 ( 3.6A); MG A 908 ( 2.7A);RIS A 901 (-2.7A)","0.31A","1yhlA-1rqjA:31.1","1yhlA-1rqjA:25.67"],["1YHL_A_RISA1400_1","1rtr","Staphylococcus aureus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ASP A  88;ARG A  93;THR A 178;GLN A 215","None","0.81A","1yhlA-1rtrA:25.0","1yhlA-1rtrA:27.08"],["1YHL_A_RISA1400_1","1wmw","Thermus thermophilus","GERANYLGERANYL DIPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  76;ARG A  88;TYR A 176;GLN A 209;ASP A 212","None","0.97A","1yhlA-1wmwA:32.4","1yhlA-1wmwA:27.60"],["1YHL_A_RISA1400_1","1wmw","Thermus thermophilus","GERANYLGERANYL DIPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  76;ASP A  79;ASP A  83;ARG A  88;GLN A 146;GLN A 209","None","1.36A","1yhlA-1wmwA:32.4","1yhlA-1wmwA:27.60"],["1YHL_A_RISA1400_1","1wmw","Thermus thermophilus","GERANYLGERANYL DIPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  76;ASP A  79;ASP A  83;ARG A  88;TYR A 176;GLN A 209","None","0.98A","1yhlA-1wmwA:32.4","1yhlA-1wmwA:27.60"],["1YHL_A_RISA1400_1","1wy0","Pyrococcus horikoshii","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  83;ASP A  90;ARG A  95;THR A 178;GLN A 215","None","0.62A","1yhlA-1wy0A:29.1","1yhlA-1wy0A:26.44"],["1YHL_A_RISA1400_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"ASP A  85;ARG A  90;LYS A 160;THR A 161;GLN A 197;ASP A 200","None","1.38A","1yhlA-2azkA:24.5","1yhlA-2azkA:26.63"],["1YHL_A_RISA1400_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  78;ASP A  81;ARG A  90;THR A 161;GLN A 197","None","0.95A","1yhlA-2azkA:24.5","1yhlA-2azkA:26.63"],["1YHL_A_RISA1400_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  78;ASP A  85;ARG A  90;THR A 161;GLN A 197;ASP A 200","None","0.84A","1yhlA-2azkA:24.5","1yhlA-2azkA:26.63"],["1YHL_A_RISA1400_1","2dh4","Saccharomyces cerevisiae","YPL069C","PF00348(polyprenyl_synt)",9,"LEU A  77;ASP A  80;ASP A  84;ARG A  89;GLN A 147;LYS A 174;THR A 175;GLN A 211;ASP A 214","None; MG A 341 (-2.6A); MG A 341 (-3.0A); MG A 341 ( 4.6A);None;None;None;None;None","0.65A","1yhlA-2dh4A:26.4","1yhlA-2dh4A:22.72"],["1YHL_A_RISA1400_1","2ftz","Thermotoga maritima","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  71;ASP A  74;ARG A  85;THR A 164;GLN A 198","None;UNL A 273 (-3.0A);UNL A 274 (-4.1A);MLY A 163 ( 3.9A);MLY A 163 ( 3.8A)","0.83A","1yhlA-2ftzA:24.9","1yhlA-2ftzA:25.53"],["1YHL_A_RISA1400_1","2ftz","Thermotoga maritima","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  71;ASP A  80;ARG A  85;THR A 164;GLN A 198","None;MLY A 223 ( 3.6A);UNL A 274 (-4.1A);MLY A 163 ( 3.9A);MLY A 163 ( 3.8A)","0.53A","1yhlA-2ftzA:24.9","1yhlA-2ftzA:25.53"],["1YHL_A_RISA1400_1","2o1o","Cryptosporidium parvum","PUTATIVE FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",9,"LEU A 112;ASP A 115;ASP A 119;ARG A 124;GLN A 184;LYS A 210;THR A 211;TYR A 214;GLN A 251","None; MG A 503 (-2.5A); MG A 502 (-2.4A);RIS A 400 (-2.9A);RIS A 400 ( 3.5A);RIS A 400 (-2.8A);RIS A 400 (-3.7A);None;RIS A 400 (-3.1A)","0.42A","1yhlA-2o1oA:36.8","1yhlA-2o1oA:27.34"],["1YHL_A_RISA1400_1","2q80","Homo sapiens","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  61;ARG A  73;GLN A 126;LYS A 151;GLN A 185;LYS A 202","None;GRG A 500 (-2.9A);GRG A 500 ( 3.5A);GRG A 500 (-2.8A);GRG A 500 (-3.2A);GRG A 500 ( 2.6A)","1.27A","1yhlA-2q80A:25.7","1yhlA-2q80A:25.54"],["1YHL_A_RISA1400_1","2q80","Homo sapiens","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",8,"LEU A  61;ASP A  64;ASP A  68;ARG A  73;GLN A 126;LYS A 151;GLN A 185;ASP A 188","None;GRG A 500 (-2.4A); MG A 400 (-2.6A);GRG A 500 (-2.9A);GRG A 500 ( 3.5A);GRG A 500 (-2.8A);GRG A 500 (-3.2A);GRG A 500 (-3.5A)","0.62A","1yhlA-2q80A:25.7","1yhlA-2q80A:25.54"],["1YHL_A_RISA1400_1","3aq0","Arabidopsis thaliana","GERANYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A 104;ASP A 107;ASP A 111;ARG A 116;LYS A 193;THR A 194","None; MG A1000 (-2.9A); MG A1001 (-2.8A);FPP A1002 (-2.9A);FPP A1002 (-2.5A);ISY A1003 (-4.7A)","0.71A","1yhlA-3aq0A:23.8","1yhlA-3aq0A:25.74"],["1YHL_A_RISA1400_1","3aqc","Micrococcus luteus","COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"ASP B  84;ASP B  88;ARG B  93;LYS B 170;THR B 171;GLN B 208;ASP B 211"," MG B 326 (-2.6A); MG B 327 (-2.4A);2DE B 329 (-3.8A);2DE B 329 (-2.5A);None;None; MG B 328 (-3.1A)","1.03A","1yhlA-3aqcB:28.2","1yhlA-3aqcB:27.01"],["1YHL_A_RISA1400_1","3aqc","Micrococcus luteus","COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU B  81;ASP B  84;ASP B  88;ARG B  93;LYS B 170;THR B 171;GLN B 208","None; MG B 326 (-2.6A); MG B 327 (-2.4A);2DE B 329 (-3.8A);2DE B 329 (-2.5A);None;None","0.85A","1yhlA-3aqcB:28.2","1yhlA-3aqcB:27.01"],["1YHL_A_RISA1400_1","3m0g","Rhodobacter capsulatus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  78;ASP A  87;ARG A  92;GLN A 153;LYS A 178","None","0.95A","1yhlA-3m0gA:24.6","1yhlA-3m0gA:27.01"],["1YHL_A_RISA1400_1","3m0g","Rhodobacter capsulatus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  78;ASP A  87;ARG A  92;LYS A 178;THR A 179","None","0.75A","1yhlA-3m0gA:24.6","1yhlA-3m0gA:27.01"],["1YHL_A_RISA1400_1","3m9u","Lactobacillus brevis","FARNESYL-DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  86;ARG A 100;THR A 184;GLN A 221;ASP A 224","GOL A 310 ( 4.3A);None;None;None;None","0.86A","1yhlA-3m9uA:25.0","1yhlA-3m9uA:24.05"],["1YHL_A_RISA1400_1","3mzv","Rhodobacter capsulatus","DECAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  90;ASP A  93;ARG A 102;LYS A 179;THR A 180;GLN A 217","None","0.79A","1yhlA-3mzvA:25.4","1yhlA-3mzvA:25.00"],["1YHL_A_RISA1400_1","3npk","Campylobacter jejuni","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  75;ASP A  78;ARG A  89;LYS A 172;THR A 173","None","1.05A","1yhlA-3npkA:26.1","1yhlA-3npkA:23.99"],["1YHL_A_RISA1400_1","3npk","Campylobacter jejuni","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  75;ASP A  84;ARG A  89;LYS A 172;THR A 173","None","0.84A","1yhlA-3npkA:26.1","1yhlA-3npkA:23.99"],["1YHL_A_RISA1400_1","3p41","Pseudomonas protegens","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",7,"LEU A  80;ASP A  83;ASP A  89;ARG A  94;GLN A 157;LYS A 180;THR A 181","None; MG A 297 (-2.5A); MG A 297 (-2.5A);DMA A 300 (-2.9A);DMA A 300 (-3.6A);POP A 301 ( 2.4A);None","0.52A","1yhlA-3p41A:24.4","1yhlA-3p41A:27.23"],["1YHL_A_RISA1400_1","3pko","Lactobacillus brevis","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  84;ASP A  87;ARG A  96;LYS A 174;THR A 175","None;None;CIT A 326 ( 4.8A);None;None","0.96A","1yhlA-3pkoA:25.5","1yhlA-3pkoA:23.51"],["1YHL_A_RISA1400_1","3pko","Lactobacillus brevis","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  84;ASP A  91;ARG A  96;LYS A 174;THR A 175","None;None;CIT A 326 ( 4.8A);None;None","0.97A","1yhlA-3pkoA:25.5","1yhlA-3pkoA:23.51"],["1YHL_A_RISA1400_1","3q1o","Helicobacter pylori","GERANYLTRANSTRANSFERASE (ISPA)","PF00348(polyprenyl_synt)",10,"LEU A  89;ASP A  92;ASP A  98;ARG A 103;GLN A 163;LYS A 186;THR A 187;GLN A 225;ASP A 228;LYS A 242","DMA A 501 ( 4.8A); MG A 400 ( 2.8A); MG A 400 ( 3.2A);DMA A 501 (-3.0A);DMA A 501 (-3.6A);DMA A 501 (-3.1A);DMA A 500 (-3.4A);DMA A 501 ( 3.8A);DMA A 501 ( 3.5A);DMA A 501 (-2.7A)","0.50A","1yhlA-3q1oA:30.3","1yhlA-3q1oA:23.36"],["1YHL_A_RISA1400_1","3qqv","Corynebacterium glutamicum","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A 105;ASP A 108;ARG A 117;GLN A 191;LYS A 215;LYS A 271","None; MG A 381 (-2.4A);DMA A 384 (-3.0A);DMA A 384 (-3.9A);DMA A 384 (-3.0A);DMA A 384 ( 2.8A)","1.37A","1yhlA-3qqvA:33.6","1yhlA-3qqvA:26.04"],["1YHL_A_RISA1400_1","3qqv","Corynebacterium glutamicum","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A 105;ASP A 108;ARG A 117;GLN A 191;LYS A 215;TYR A 219","None; MG A 381 (-2.4A);DMA A 384 (-3.0A);DMA A 384 (-3.9A);DMA A 384 (-3.0A);DMA A 384 ( 4.9A)","1.05A","1yhlA-3qqvA:33.6","1yhlA-3qqvA:26.04"],["1YHL_A_RISA1400_1","3qqv","Corynebacterium glutamicum","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A 105;ASP A 108;ASP A 112;ARG A 117;GLN A 191;LYS A 215","None; MG A 381 (-2.4A); MG A 381 (-2.8A);DMA A 384 (-3.0A);DMA A 384 (-3.9A);DMA A 384 (-3.0A)","0.77A","1yhlA-3qqvA:33.6","1yhlA-3qqvA:26.04"],["1YHL_A_RISA1400_1","3qqv","Corynebacterium glutamicum","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU A 105;ASP A 108;ASP A 112;ARG A 117;LYS A 215;THR A 216;GLN A 254","None; MG A 381 (-2.4A); MG A 381 (-2.8A);DMA A 384 (-3.0A);DMA A 384 (-3.0A);DMA A 383 ( 4.0A);DMA A 383 (-3.2A)","0.61A","1yhlA-3qqvA:33.6","1yhlA-3qqvA:26.04"],["1YHL_A_RISA1400_1","3tc1","Helicobacter pylori","OCTAPRENYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  74;ASP A  77;LYS A 162;THR A 163;GLN A 197","None","0.73A","1yhlA-3tc1A:25.1","1yhlA-3tc1A:22.37"],["1YHL_A_RISA1400_1","3tc1","Helicobacter pylori","OCTAPRENYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  74;LYS A 162;THR A 163;GLN A 197;ASP A 200","None;None;None;None; MG A 500 (-2.9A)","0.47A","1yhlA-3tc1A:25.1","1yhlA-3tc1A:22.37"],["1YHL_A_RISA1400_1","3ts7","Methylococcus capsulatus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  85;ASP A  88;ASP A  94;LYS A 185;THR A 186","None","1.13A","1yhlA-3ts7A:24.9","1yhlA-3ts7A:26.23"],["1YHL_A_RISA1400_1","3ts7","Methylococcus capsulatus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  85;ASP A  94;ARG A  99;LYS A 185;THR A 186","None","0.78A","1yhlA-3ts7A:24.9","1yhlA-3ts7A:26.23"],["1YHL_A_RISA1400_1","3wjo","Escherichia coli","OCTAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  81;ARG A  93;LYS A 170;THR A 171;GLN A 208;ASP A 211","None;IPE A 401 ( 4.2A);IPE A 401 ( 2.9A);IPE A 402 ( 3.8A);IPE A 402 (-3.6A);IPE A 402 ( 4.6A)","0.91A","1yhlA-3wjoA:25.2","1yhlA-3wjoA:26.80"],["1YHL_A_RISA1400_1","3wjo","Escherichia coli","OCTAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  81;ASP A  84;ARG A  93;LYS A 170;THR A 171;GLN A 208","None;IPE A 401 (-2.6A);IPE A 401 ( 4.2A);IPE A 401 ( 2.9A);IPE A 402 ( 3.8A);IPE A 402 (-3.6A)","0.88A","1yhlA-3wjoA:25.2","1yhlA-3wjoA:26.80"],["1YHL_A_RISA1400_1","3wjo","Escherichia coli","OCTAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  81;ASP A  84;ASP A  88;ARG A  93;LYS A 170;THR A 171","None;IPE A 401 (-2.6A);IPE A 401 (-3.3A);IPE A 401 ( 4.2A);IPE A 401 ( 2.9A);IPE A 402 ( 3.8A)","0.89A","1yhlA-3wjoA:25.2","1yhlA-3wjoA:26.80"],["1YHL_A_RISA1400_1","3zou","Pseudomonas aeruginosa","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  80;ASP A  83;ASP A  89;ARG A  94;GLN A 157","None; MG A1295 (-2.5A); MG A1295 (-2.4A);GPP A1297 (-3.0A);GPP A1297 (-3.7A)","0.45A","1yhlA-3zouA:24.1","1yhlA-3zouA:25.27"],["1YHL_A_RISA1400_1","3zou","Pseudomonas aeruginosa","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  80;ASP A  83;ASP A  89;ARG A  94;LYS A 180;THR A 181","None; MG A1295 (-2.5A); MG A1295 (-2.4A);GPP A1297 (-3.0A);GPP A1297 (-3.0A);None","0.57A","1yhlA-3zouA:24.1","1yhlA-3zouA:25.27"],["1YHL_A_RISA1400_1","4e1e","Trypanosoma cruzi","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",11,"LEU A  95;ASP A  98;ASP A 102;ARG A 107;GLN A 167;LYS A 207;THR A 208;TYR A 211;GLN A 247;ASP A 250;LYS A 264","None; MG A 403 (-2.5A); MG A 403 (-2.4A);0MW A 404 (-2.7A);0MW A 404 (-3.7A);0MW A 404 (-2.8A);IPE A 405 ( 4.6A);None;0MW A 404 ( 3.8A); MG A 401 (-2.7A);0MW A 404 ( 3.0A)","0.46A","1yhlA-4e1eA:57.0","1yhlA-4e1eA:100.00"],["1YHL_A_RISA1400_1","4f62","Marinomonas sp. MED121","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  80;ASP A  83;ASP A  89;LYS A 178;THR A 179","None","0.88A","1yhlA-4f62A:24.0","1yhlA-4f62A:27.72"],["1YHL_A_RISA1400_1","4f62","Marinomonas sp. MED121","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  80;ASP A  83;GLN A 155;LYS A 178;THR A 179","None","1.07A","1yhlA-4f62A:24.0","1yhlA-4f62A:27.72"],["1YHL_A_RISA1400_1","4fp4","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"ASP A  86;ASP A  90;ARG A  95;GLN A 147;GLN A 199","UNX A 302 ( 2.6A);UNX A 302 ( 3.2A);UNX A 302 ( 4.6A);GER A 301 ( 4.7A);None","1.05A","1yhlA-4fp4A:21.2","1yhlA-4fp4A:23.83"],["1YHL_A_RISA1400_1","4fp4","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"ASP A  86;ASP A  90;ARG A  95;THR A 163;GLN A 199","UNX A 302 ( 2.6A);UNX A 302 ( 3.2A);UNX A 302 ( 4.6A);None;None","0.78A","1yhlA-4fp4A:21.2","1yhlA-4fp4A:23.83"],["1YHL_A_RISA1400_1","4fp4","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  83;ASP A  86;ASP A  90;ARG A  95;LYS A 162;THR A 163","UNL A 303 ( 4.7A);UNX A 302 ( 2.6A);UNX A 302 ( 3.2A);UNX A 302 ( 4.6A);GER A 301 ( 4.8A);None","1.05A","1yhlA-4fp4A:21.2","1yhlA-4fp4A:23.83"],["1YHL_A_RISA1400_1","4gp1","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  82;ASP A  85;ARG A  94;LYS A 184;THR A 185","None","0.95A","1yhlA-4gp1A:28.4","1yhlA-4gp1A:26.85"],["1YHL_A_RISA1400_1","4gp1","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  82;ASP A  85;ASP A  89;ARG A  94;LYS A 184","None","0.90A","1yhlA-4gp1A:28.4","1yhlA-4gp1A:26.85"],["1YHL_A_RISA1400_1","4jxy","Pseudoalteromonas atlantica","TRANS-HEXAPRENYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  81;ASP A  84;LYS A 170;THR A 171;GLN A 208","None","0.89A","1yhlA-4jxyA:24.9","1yhlA-4jxyA:25.19"],["1YHL_A_RISA1400_1","4jxy","Pseudoalteromonas atlantica","TRANS-HEXAPRENYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  81;LYS A 170;THR A 171;GLN A 208;ASP A 211","None","0.82A","1yhlA-4jxyA:24.9","1yhlA-4jxyA:25.19"],["1YHL_A_RISA1400_1","4jzx","Leishmania major","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"ASP A  98;ARG A 107;GLN A 247;ASP A 250;LYS A 264"," CA A 403 (-2.5A);476 A 402 (-2.9A);IPE A 401 (-3.7A); CA A 404 (-3.0A);476 A 402 (-2.9A)","1.13A","1yhlA-4jzxA:54.0","1yhlA-4jzxA:63.54"],["1YHL_A_RISA1400_1","4jzx","Leishmania major","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",8,"LEU A  95;ASP A  98;ASP A 102;ARG A 107;GLN A 167;GLN A 247;ASP A 250;LYS A 264","None; CA A 403 (-2.5A); CA A 403 (-2.5A);476 A 402 (-2.9A);476 A 402 (-3.5A);IPE A 401 (-3.7A); CA A 404 (-3.0A);476 A 402 (-2.9A)","0.63A","1yhlA-4jzxA:54.0","1yhlA-4jzxA:63.54"],["1YHL_A_RISA1400_1","4jzx","Leishmania major","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",10,"LEU A  95;ASP A  98;ASP A 102;ARG A 107;LYS A 207;THR A 208;TYR A 211;GLN A 247;ASP A 250;LYS A 264","None; CA A 403 (-2.5A); CA A 403 (-2.5A);476 A 402 (-2.9A);476 A 402 (-2.7A);IPE A 401 ( 3.4A);None;IPE A 401 (-3.7A); CA A 404 (-3.0A);476 A 402 (-2.9A)","0.44A","1yhlA-4jzxA:54.0","1yhlA-4jzxA:63.54"],["1YHL_A_RISA1400_1","4kk2","Artemisia spiciformis","MONOTERPENE SYNTHASE FDS-5, CHLOROPLASTIC - FARNESYL DIPHOSPHATE SYNTHASE 1 CHIMERA","PF00348(polyprenyl_synt)",6,"LEU A  94;ASP A  97;ARG A 106;LYS A 194;THR A 195;TYR A 198","None","1.00A","1yhlA-4kk2A:40.5","1yhlA-4kk2A:38.01"],["1YHL_A_RISA1400_1","4kkm","Zymomonas mobilis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  83;ASP A  86;ASP A  92;ARG A  97;GLN A 159;THR A 185","None","0.67A","1yhlA-4kkmA:25.0","1yhlA-4kkmA:25.19"],["1YHL_A_RISA1400_1","4kkm","Zymomonas mobilis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  83;ASP A  92;ARG A  97;LYS A 184;THR A 185","None","1.16A","1yhlA-4kkmA:25.0","1yhlA-4kkmA:25.19"],["1YHL_A_RISA1400_1","4lfe","Streptococcus uberis","GERANYLGERANYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU A  75;ARG A  89;GLN A 149;LYS A 172;THR A 173;GLN A 210;ASP A 213","IPE A 301 (-4.7A);IPE A 301 (-2.8A);IPE A 301 ( 3.7A);IPE A 301 (-3.0A);None;None;None","0.88A","1yhlA-4lfeA:25.9","1yhlA-4lfeA:24.31"],["1YHL_A_RISA1400_1","4lfe","Streptococcus uberis","GERANYLGERANYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",8,"LEU A  75;ASP A  78;ASP A  84;ARG A  89;GLN A 149;LYS A 172;THR A 173;GLN A 210","IPE A 301 (-4.7A); MG A 302 (-2.5A); MG A 302 (-2.4A);IPE A 301 (-2.8A);IPE A 301 ( 3.7A);IPE A 301 (-3.0A);None;None","0.69A","1yhlA-4lfeA:25.9","1yhlA-4lfeA:24.31"],["1YHL_A_RISA1400_1","4lls","Roseobacter denitrificans","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",7,"LEU A  77;ASP A  80;ASP A  86;ARG A  91;GLN A 153;ASP A 216;LYS A 230","None; CA A 304 ( 2.9A); CA A 305 (-2.3A);GST A 302 (-2.9A);GST A 302 (-3.7A); CA A 303 (-2.9A);GST A 302 (-2.7A)","0.75A","1yhlA-4llsA:28.9","1yhlA-4llsA:26.77"],["1YHL_A_RISA1400_1","4lls","Roseobacter denitrificans","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",8,"LEU A  77;ASP A  80;ASP A  86;ARG A  91;LYS A 178;THR A 179;ASP A 216;LYS A 230","None; CA A 304 ( 2.9A); CA A 305 (-2.3A);GST A 302 (-2.9A);GST A 302 (-3.4A);IPE A 301 (-4.2A); CA A 303 (-2.9A);GST A 302 (-2.7A)","0.62A","1yhlA-4llsA:28.9","1yhlA-4llsA:26.77"],["1YHL_A_RISA1400_1","4lls","Roseobacter denitrificans","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",8,"LEU A  77;ASP A  80;ASP A  86;ARG A  91;THR A 179;GLN A 213;ASP A 216;LYS A 230","None; CA A 304 ( 2.9A); CA A 305 (-2.3A);GST A 302 (-2.9A);IPE A 301 (-4.2A);IPE A 301 ( 4.1A); CA A 303 (-2.9A);GST A 302 (-2.7A)","0.58A","1yhlA-4llsA:28.9","1yhlA-4llsA:26.77"],["1YHL_A_RISA1400_1","4lob","Acinetobacter baumannii","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  85;ASP A  88;LYS A 174;THR A 175;GLN A 211","None","0.88A","1yhlA-4lobA:26.4","1yhlA-4lobA:25.13"],["1YHL_A_RISA1400_1","4lob","Acinetobacter baumannii","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  85;LYS A 174;THR A 175;GLN A 211;ASP A 214","None","0.87A","1yhlA-4lobA:26.4","1yhlA-4lobA:25.13"],["1YHL_A_RISA1400_1","4p0v","Homo sapiens","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",11,"LEU A 100;ASP A 103;ASP A 107;ARG A 112;GLN A 171;LYS A 200;THR A 201;TYR A 204;GLN A 240;ASP A 243;LYS A 257","None; MG A 405 (-2.5A); MG A 405 (-2.4A);ZOL A 401 ( 2.7A);ZOL A 401 ( 3.8A);ZOL A 401 (-2.7A);ZOL A 401 (-3.7A);None;ZOL A 401 (-3.5A); MG A 404 (-2.8A);1WO A 402 ( 2.8A)","0.30A","1yhlA-4p0vA:45.8","1yhlA-4p0vA:37.97"],["1YHL_A_RISA1400_1","4rxe","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",9,"ASP A 103;ASP A 107;ARG A 112;GLN A 172;LYS A 212;THR A 213;GLN A 252;ASP A 255;LYS A 269"," MG A3004 (-2.5A); MG A3004 (-2.3A);3YQ A3001 (-2.8A); MG A3004 ( 3.8A);3YQ A3001 (-2.9A);3YQ A3001 (-4.2A);3YQ A3001 ( 4.2A); MG A3003 ( 2.9A);3YQ A3001 (-3.1A)","0.78A","1yhlA-4rxeA:52.9","1yhlA-4rxeA:66.15"],["1YHL_A_RISA1400_1","4rxe","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",9,"ASP A 103;ASP A 107;ARG A 112;GLN A 172;LYS A 212;THR A 213;TYR A 216;GLN A 252;ASP A 255"," MG A3004 (-2.5A); MG A3004 (-2.3A);3YQ A3001 (-2.8A); MG A3004 ( 3.8A);3YQ A3001 (-2.9A);3YQ A3001 (-4.2A);3YQ A3001 (-4.7A);3YQ A3001 ( 4.2A); MG A3003 ( 2.9A)","0.30A","1yhlA-4rxeA:52.9","1yhlA-4rxeA:66.15"],["1YHL_A_RISA1400_1","4rxe","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",8,"LEU A 100;ASP A 103;ASP A 107;ARG A 112;GLN A 172;LYS A 212;TYR A 216;ASP A 255","3YQ A3001 ( 4.6A); MG A3004 (-2.5A); MG A3004 (-2.3A);3YQ A3001 (-2.8A); MG A3004 ( 3.8A);3YQ A3001 (-2.9A);3YQ A3001 (-4.7A); MG A3003 ( 2.9A)","0.57A","1yhlA-4rxeA:52.9","1yhlA-4rxeA:66.15"],["1YHL_A_RISA1400_1","4wk5","Thermotoga neapolitana","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",6,"LEU A  71;ASP A  80;ARG A  85;THR A 164;GLN A 198;ASP A 201","None","0.76A","1yhlA-4wk5A:24.7","1yhlA-4wk5A:25.66"],["1YHL_A_RISA1400_1","5ahu","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",11,"LEU B 100;ASP B 103;ASP B 107;ARG B 112;GLN B 172;LYS B 212;THR B 213;TYR B 216;GLN B 252;ASP B 255;LYS B 269","None; MG B1370 (-2.5A); MG B1369 (-2.2A);G76 B1368 (-2.8A);G76 B1368 ( 4.1A);G76 B1368 (-2.8A);G76 B1368 (-4.2A);None;G76 B1368 ( 4.0A); MG B1371 ( 3.0A);G76 B1368 (-3.1A)","0.53A","1yhlA-5ahuB:39.9","1yhlA-5ahuB:73.47"],["1YHL_A_RISA1400_1","5ayp","Geobacillus stearothermophilus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  83;ASP A  86;ASP A  92;ARG A  97;GLN A 160;THR A 184","None","0.73A","1yhlA-5aypA:23.9","1yhlA-5aypA:26.53"],["1YHL_A_RISA1400_1","5ayp","Geobacillus stearothermophilus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  83;ASP A  92;ARG A  97;GLN A 160;LYS A 183;THR A 184","None","0.94A","1yhlA-5aypA:23.9","1yhlA-5aypA:26.53"],["1YHL_A_RISA1400_1","5e8l","Arabidopsis thaliana","HETERODIMERIC GERANYLGERANYL PYROPHOSPHATE SYNTHASE LARGE SUBUNIT 1, CHLOROPLASTIC","PF00348(polyprenyl_synt)",5,"LEU A  88;ASP A  91;ASP A  97;ARG A 102;GLN A 166","None","0.97A","1yhlA-5e8lA:24.0","1yhlA-5e8lA:25.77"],["1YHL_A_RISA1400_1","5h9d","Staphylococcus aureus","FARNESYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  79;ASP A  82;ARG A  91;LYS A 168;THR A 169;GLN A 206","PO4 A 501 (-4.5A);None;PO4 A 501 ( 4.9A);None;None;None","0.98A","1yhlA-5h9dA:28.8","1yhlA-5h9dA:26.15"],["1YHL_A_RISA1400_1","5h9d","Staphylococcus aureus","FARNESYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ASP A  86;ARG A  91;LYS A 168;THR A 169","PO4 A 501 (-4.5A);None;PO4 A 501 ( 4.9A);None;None","0.85A","1yhlA-5h9dA:28.8","1yhlA-5h9dA:26.15"],["1YHL_A_RISA1400_1","5h9d","Staphylococcus aureus","FARNESYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  79;LYS A 168;THR A 169;GLN A 206;ASP A 209","PO4 A 501 (-4.5A);None;None;None;None","0.98A","1yhlA-5h9dA:28.8","1yhlA-5h9dA:26.15"],["1YHL_A_RISA1400_1","5hn7","Plasmodium vivax","FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE","PF00348(polyprenyl_synt)",9,"ASP A 126;ASP A 130;ARG A 135;GLN A 195;LYS A 243;TYR A 247;GLN A 284;ASP A 287;LYS A 301","04M A 401 ( 4.0A);None;04M A 401 (-3.5A);04M A 401 (-3.3A);04M A 401 (-4.5A);04M A 401 (-4.5A);None;None;04M A 401 ( 3.9A)","0.73A","1yhlA-5hn7A:43.4","1yhlA-5hn7A:31.01"],["1YHL_A_RISA1400_1","5hn7","Plasmodium vivax","FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE","PF00348(polyprenyl_synt)",9,"ASP A 126;ASP A 130;ARG A 135;LYS A 243;THR A 244;TYR A 247;GLN A 284;ASP A 287;LYS A 301","04M A 401 ( 4.0A);None;04M A 401 (-3.5A);04M A 401 (-4.5A);04M A 401 ( 3.8A);04M A 401 (-4.5A);None;None;04M A 401 ( 3.9A)","0.57A","1yhlA-5hn7A:43.4","1yhlA-5hn7A:31.01"],["1YHL_A_RISA1400_1","6b07","Choristoneura fumiferana","FARNESYL DIPHOSPHATE SYNTHASE","no annotation",10,"ASP A 147;ASP A 151;ARG A 156;GLN A 215;LYS A 244;THR A 245;TYR A 248;GLN A 284;ASP A 287;LYS A 301"," MG A 402 (-2.6A); MG A 402 (-2.5A);C6M A 401 (-2.7A);C6M A 401 (-3.3A);C6M A 401 (-2.6A);C6M A 401 (-3.6A);None;C6M A 401 (-3.7A); MG A 404 ( 2.7A);C6M A 401 (-2.9A)","0.42A","1yhlA-6b07A:43.9","1yhlA-6b07A:12.36"]]