SIMILAR PATTERNS OF AMINO ACIDS FOR 1YC2_E_NCAE509

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ftp MUSCLE FATTY ACID
BINDING PROTEIN

(Schistocerca
gregaria) 		PF00061
(Lipocalin) 		4 ASP A  89
GLU A 109
ARG A 108
LYS A  93
 None
 1.39A 1yc2A-1ftpA:
undetectable
1yc2B-1ftpA:
undetectable
1yc2E-1ftpA:
undetectable		 1yc2A-1ftpA:
19.66
1yc2B-1ftpA:
19.66
1yc2E-1ftpA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4p GLUCAN
1,3-BETA-GLUCOSIDASE
I/II

(Saccharomyces
cerevisiae) 		PF00150
(Cellulase) 		4 ASP A 383
GLU A 387
TYR A 439
ARG A 390
 None
 1.42A 1yc2A-1h4pA:
0.5
1yc2B-1h4pA:
1.9
1yc2E-1h4pA:
0.0		 1yc2A-1h4pA:
19.66
1yc2B-1h4pA:
19.66
1yc2E-1h4pA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1owa SPECTRIN ALPHA
CHAIN, ERYTHROCYTE

(Homo sapiens) 		PF00435
(Spectrin) 		4 LYS A 104
ASP A  64
GLU A  71
LYS A  67
 None
 1.26A 1yc2A-1owaA:
undetectable
1yc2B-1owaA:
undetectable
1yc2E-1owaA:
undetectable		 1yc2A-1owaA:
22.31
1yc2B-1owaA:
22.31
1yc2E-1owaA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcl HEMOLYTIC LECTIN
CEL-III

(Cucumaria
echinata) 		PF00652
(Ricin_B_lectin) 		4 ASP A 276
GLU A 161
TYR A 243
ARG A 159
 CA  A1005 (-2.9A)
None
None
None
 1.49A 1yc2A-1vclA:
undetectable
1yc2B-1vclA:
undetectable
1yc2E-1vclA:
0.0		 1yc2A-1vclA:
22.48
1yc2B-1vclA:
22.48
1yc2E-1vclA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtz RIBOSE-5-PHOSPHATE
ISOMERASE

(Saccharomyces
cerevisiae) 		PF06026
(Rib_5-P_isom_A) 		4 ASP A 144
GLU A  19
ARG A  23
LYS A  22
 None
 1.29A 1yc2A-1xtzA:
2.8
1yc2B-1xtzA:
0.0
1yc2E-1xtzA:
3.2		 1yc2A-1xtzA:
22.15
1yc2B-1xtzA:
22.15
1yc2E-1xtzA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y7u ACYL-COA HYDROLASE

(Bacillus cereus) 		PF03061
(4HBT) 		4 ASP A  27
GLU A  42
TYR A  81
LYS A  38
 None
 1.39A 1yc2A-1y7uA:
undetectable
1yc2B-1y7uA:
undetectable
1yc2E-1y7uA:
0.0		 1yc2A-1y7uA:
22.61
1yc2B-1y7uA:
22.61
1yc2E-1y7uA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0r NICOTINAMIDASE

(Saccharomyces
cerevisiae) 		PF00857
(Isochorismatase) 		4 LYS A 201
ASP A 195
GLU A 165
TYR A 166
 None
 1.33A 1yc2A-2h0rA:
5.0
1yc2B-2h0rA:
4.2
1yc2E-2h0rA:
0.8		 1yc2A-2h0rA:
21.77
1yc2B-2h0rA:
21.77
1yc2E-2h0rA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k4x 30S RIBOSOMAL
PROTEIN S27AE

(Thermoplasma
acidophilum) 		PF01599
(Ribosomal_S27) 		4 GLU A  32
TYR A  37
ARG A  19
LYS A  17
 None
 1.16A 1yc2A-2k4xA:
undetectable
1yc2B-2k4xA:
undetectable
1yc2E-2k4xA:
undetectable		 1yc2A-2k4xA:
11.86
1yc2B-2k4xA:
11.86
1yc2E-2k4xA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2llz UNCHARACTERIZED
PROTEIN YJDK

(Escherichia
coli) 		PF11080
(GhoS) 		4 ASP A  92
GLU A  45
TYR A  46
ARG A  50
 None
 1.45A 1yc2A-2llzA:
undetectable
1yc2B-2llzA:
undetectable
1yc2E-2llzA:
undetectable		 1yc2A-2llzA:
14.45
1yc2B-2llzA:
14.45
1yc2E-2llzA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ooe CLEAVAGE STIMULATION
FACTOR 77 KDA
SUBUNIT

(Mus musculus) 		PF05843
(Suf) 		4 ASP A  82
GLU A  75
TYR A  71
LYS A  83
 None
 1.37A 1yc2A-2ooeA:
0.0
1yc2B-2ooeA:
0.0
1yc2E-2ooeA:
0.0		 1yc2A-2ooeA:
19.05
1yc2B-2ooeA:
19.05
1yc2E-2ooeA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y38 LAMININ SUBUNIT
ALPHA-5

(Mus musculus) 		PF00053
(Laminin_EGF)
PF00055
(Laminin_N) 		4 ASP A 298
GLU A 234
ARG A 171
LYS A 165
 None
 1.45A 1yc2A-2y38A:
0.0
1yc2B-2y38A:
0.0
1yc2E-2y38A:
0.0		 1yc2A-2y38A:
19.91
1yc2B-2y38A:
19.91
1yc2E-2y38A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yhe SEC-ALKYL SULFATASE

(Pseudomonas sp.
DSM 6611) 		PF00753
(Lactamase_B)
PF14863
(Alkyl_sulf_dimr)
PF14864
(Alkyl_sulf_C) 		4 ASP A  33
GLU A 506
TYR A 510
LYS A  35
 None
 1.42A 1yc2A-2yheA:
undetectable
1yc2B-2yheA:
undetectable
1yc2E-2yheA:
undetectable		 1yc2A-2yheA:
18.84
1yc2B-2yheA:
18.84
1yc2E-2yheA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr1 3-DEHYDROQUINATE
DEHYDRATASE

(Geobacillus
kaustophilus) 		PF01487
(DHquinase_I) 		4 ASP A  54
GLU A 121
TYR A 124
ARG A  89
 None
 1.41A 1yc2A-2yr1A:
undetectable
1yc2B-2yr1A:
1.8
1yc2E-2yr1A:
0.7		 1yc2A-2yr1A:
23.78
1yc2B-2yr1A:
23.78
1yc2E-2yr1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0u RESPONSE REGULATOR

(Thermotoga
maritima) 		PF00072
(Response_reg) 		4 ASP A 105
GLU A  24
TYR A  26
LYS A 108
 None
 1.19A 1yc2A-3a0uA:
4.6
1yc2B-3a0uA:
4.6
1yc2E-3a0uA:
4.4		 1yc2A-3a0uA:
19.07
1yc2B-3a0uA:
19.07
1yc2E-3a0uA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3atp METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I

(Escherichia
coli) 		PF02203
(TarH) 		4 ASP A 130
GLU A 109
TYR A 108
LYS A 126
 None
 1.30A 1yc2A-3atpA:
undetectable
1yc2B-3atpA:
undetectable
1yc2E-3atpA:
undetectable		 1yc2A-3atpA:
19.38
1yc2B-3atpA:
19.38
1yc2E-3atpA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bit FACT COMPLEX SUBUNIT
SPT16

(Saccharomyces
cerevisiae) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		4 ASP A 384
GLU A 343
ARG A 336
LYS A 339
 None
 1.11A 1yc2A-3bitA:
undetectable
1yc2B-3bitA:
undetectable
1yc2E-3bitA:
undetectable		 1yc2A-3bitA:
19.65
1yc2B-3bitA:
19.65
1yc2E-3bitA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bws PROTEIN LP49

(Leptospira
interrogans) 		PF10282
(Lactonase) 		4 ASP A 258
GLU A 269
ARG A 271
LYS A 272
 None
 1.50A 1yc2A-3bwsA:
undetectable
1yc2B-3bwsA:
undetectable
1yc2E-3bwsA:
undetectable		 1yc2A-3bwsA:
20.50
1yc2B-3bwsA:
20.50
1yc2E-3bwsA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE ALPHA SUBUNIT

(Methanosarcina
barkeri) 		PF03063
(Prismane) 		4 LYS A 196
ASP A 192
GLU A 190
ARG A 104
 None
None
None
SF4  A 810 (-3.6A)
 1.50A 1yc2A-3cf4A:
5.1
1yc2B-3cf4A:
5.6
1yc2E-3cf4A:
5.5		 1yc2A-3cf4A:
17.10
1yc2B-3cf4A:
17.10
1yc2E-3cf4A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cfy PUTATIVE LUXO
REPRESSOR PROTEIN

(Vibrio
parahaemolyticus) 		PF00072
(Response_reg) 		4 ASP A 108
GLU A  25
TYR A  27
LYS A 111
 None
 0.94A 1yc2A-3cfyA:
5.1
1yc2B-3cfyA:
5.0
1yc2E-3cfyA:
4.8		 1yc2A-3cfyA:
20.16
1yc2B-3cfyA:
20.16
1yc2E-3cfyA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A'
DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus;
Sulfolobus
solfataricus) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 LYS B 341
ASP B 336
TYR A 761
ARG B 452
 None
 1.19A 1yc2A-3hkzB:
undetectable
1yc2B-3hkzB:
undetectable
1yc2E-3hkzB:
undetectable		 1yc2A-3hkzB:
12.34
1yc2B-3hkzB:
12.34
1yc2E-3hkzB:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3otd TRNA(HIS)
GUANYLYLTRANSFERASE

(Homo sapiens) 		PF04446
(Thg1)
PF14413
(Thg1C) 		4 ASP A  67
GLU A 267
ARG A  84
LYS A  83
 None
 0.98A 1yc2A-3otdA:
undetectable
1yc2B-3otdA:
undetectable
1yc2E-3otdA:
undetectable		 1yc2A-3otdA:
20.63
1yc2B-3otdA:
20.63
1yc2E-3otdA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shm CAPSID PROTEIN VP1

(Adeno-associated
dependoparvovirus
A) 		PF00740
(Parvo_coat) 		4 LYS A 567
ASP A 529
GLU A 575
LYS A 528
 None
 1.44A 1yc2A-3shmA:
undetectable
1yc2B-3shmA:
undetectable
1yc2E-3shmA:
undetectable		 1yc2A-3shmA:
18.02
1yc2B-3shmA:
18.02
1yc2E-3shmA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u5s FAD-LINKED
SULFHYDRYL OXIDASE
ALR

(Homo sapiens) 		PF04777
(Evr1_Alr) 		4 ASP A 187
GLU A 193
ARG A 194
LYS A 190
 None
None
FAD  A 300 (-4.0A)
None
 1.34A 1yc2A-3u5sA:
undetectable
1yc2B-3u5sA:
undetectable
1yc2E-3u5sA:
undetectable		 1yc2A-3u5sA:
18.08
1yc2B-3u5sA:
18.08
1yc2E-3u5sA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gp1 POLYPRENYL
SYNTHETASE

(Pyrobaculum
calidifontis) 		PF00348
(polyprenyl_synt) 		4 ASP A 244
GLU A 155
ARG A 250
LYS A 249
 None
 1.12A 1yc2A-4gp1A:
undetectable
1yc2B-4gp1A:
undetectable
1yc2E-4gp1A:
undetectable		 1yc2A-4gp1A:
23.02
1yc2B-4gp1A:
23.02
1yc2E-4gp1A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhr ALPHA-DIOXYGENASE

(Arabidopsis
thaliana) 		PF03098
(An_peroxidase) 		4 ASP A 171
GLU A 489
TYR A 485
LYS A 196
 None
 1.44A 1yc2A-4hhrA:
undetectable
1yc2B-4hhrA:
undetectable
1yc2E-4hhrA:
undetectable		 1yc2A-4hhrA:
17.05
1yc2B-4hhrA:
17.05
1yc2E-4hhrA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7h PEROXIDE STRESS
SENSING REGULATOR

(Streptococcus
pyogenes) 		PF01475
(FUR) 		4 ASP A  75
GLU A  81
TYR A  92
LYS A  71
 None
 1.44A 1yc2A-4i7hA:
undetectable
1yc2B-4i7hA:
undetectable
1yc2E-4i7hA:
undetectable		 1yc2A-4i7hA:
22.44
1yc2B-4i7hA:
22.44
1yc2E-4i7hA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pj6 LEUCYL-CYSTINYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 ASP A 281
GLU A 365
TYR A 325
LYS A 287
 None
 1.49A 1yc2A-4pj6A:
undetectable
1yc2B-4pj6A:
undetectable
1yc2E-4pj6A:
undetectable		 1yc2A-4pj6A:
14.72
1yc2B-4pj6A:
14.72
1yc2E-4pj6A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pn0 MRNA-CAPPING ENZYME
SUBUNIT BETA

(Schizosaccharomyces
pombe) 		PF02940
(mRNA_triPase) 		4 ASP A 228
GLU A 255
ARG A 256
LYS A 243
 None
 1.49A 1yc2A-4pn0A:
undetectable
1yc2B-4pn0A:
undetectable
1yc2E-4pn0A:
undetectable		 1yc2A-4pn0A:
21.07
1yc2B-4pn0A:
21.07
1yc2E-4pn0A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4raa PUTATIVE EXPORTED
PROTEIN

(Bacteroides
fragilis) 		PF17170
(DUF5128) 		4 ASP A 126
GLU A 145
ARG A 146
LYS A 131
 None
None
PO4  A 400 (-3.7A)
None
 1.37A 1yc2A-4raaA:
undetectable
1yc2B-4raaA:
undetectable
1yc2E-4raaA:
undetectable		 1yc2A-4raaA:
18.90
1yc2B-4raaA:
18.90
1yc2E-4raaA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgt PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF02876
(Stap_Strp_tox_C)
PF09199
(SSL_OB) 		4 LYS A 145
GLU A 227
ARG A 138
LYS A 139
 None
 1.36A 1yc2A-4rgtA:
undetectable
1yc2B-4rgtA:
undetectable
1yc2E-4rgtA:
undetectable		 1yc2A-4rgtA:
22.76
1yc2B-4rgtA:
22.76
1yc2E-4rgtA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxe FARNESYL
PYROPHOSPHATE
SYNTHASE

(Trypanosoma
brucei) 		PF00348
(polyprenyl_synt) 		4 GLU A 330
TYR A 250
ARG A 365
LYS A 364
 None
 1.29A 1yc2A-4rxeA:
undetectable
1yc2B-4rxeA:
undetectable
1yc2E-4rxeA:
undetectable		 1yc2A-4rxeA:
20.97
1yc2B-4rxeA:
20.97
1yc2E-4rxeA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v19 MITORIBOSOMAL
PROTEIN BL32M,
MRPL32

(Sus scrofa) 		PF01783
(Ribosomal_L32p) 		4 ASP 5 169
GLU 5 155
ARG 5 173
LYS 5 172
 None
 1.32A 1yc2A-4v195:
undetectable
1yc2B-4v195:
undetectable
1yc2E-4v195:
undetectable		 1yc2A-4v195:
20.23
1yc2B-4v195:
20.23
1yc2E-4v195:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ahu FARNESYL
PYROPHOSPHATE
SYNTHASE

(Trypanosoma
brucei) 		PF00348
(polyprenyl_synt) 		4 GLU B 330
TYR B 250
ARG B 365
LYS B 364
 None
 1.23A 1yc2A-5ahuB:
undetectable
1yc2B-5ahuB:
undetectable
1yc2E-5ahuB:
undetectable		 1yc2A-5ahuB:
22.44
1yc2B-5ahuB:
22.44
1yc2E-5ahuB:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ibo OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT

(Oplophorus
gracilirostris) 		no annotation 4 ASP A 121
GLU A 140
ARG A 141
LYS A 124
 None
 1.49A 1yc2A-5iboA:
undetectable
1yc2B-5iboA:
undetectable
1yc2E-5iboA:
undetectable		 1yc2A-5iboA:
20.52
1yc2B-5iboA:
20.52
1yc2E-5iboA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t4y SUSC HOMOLOG

(Bacteroides
thetaiotaomicron) 		no annotation 4 ASP D 450
GLU D 514
ARG D 513
LYS D 485
 None
 1.38A 1yc2A-5t4yD:
undetectable
1yc2B-5t4yD:
undetectable
1yc2E-5t4yD:
undetectable		 1yc2A-5t4yD:
13.65
1yc2B-5t4yD:
13.65
1yc2E-5t4yD:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj6 HIGH CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL

(Aplysia
californica) 		PF00520
(Ion_trans)
PF03493
(BK_channel_a) 		4 ASP A 361
GLU A 328
ARG A 329
LYS A 331
 None
MG  A1106 ( 4.9A)
None
None
 1.34A 1yc2A-5tj6A:
3.5
1yc2B-5tj6A:
3.5
1yc2E-5tj6A:
3.4		 1yc2A-5tj6A:
12.15
1yc2B-5tj6A:
12.15
1yc2E-5tj6A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w40 POPP2 PROTEIN

(Ralstonia
solanacearum) 		PF03421
(Acetyltransf_14) 		4 GLU A 284
TYR A 290
ARG A 282
LYS A 283
 None
 1.14A 1yc2A-5w40A:
undetectable
1yc2B-5w40A:
undetectable
1yc2E-5w40A:
undetectable		 1yc2A-5w40A:
23.14
1yc2B-5w40A:
23.14
1yc2E-5w40A:
23.14