SIMILAR PATTERNS OF AMINO ACIDS FOR 1YAJ_F_BEZF5023

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ac5 KEX1(DELTA)P

(Saccharomyces
cerevisiae) 		PF00450
(Peptidase_S10) 		4 GLY A  76
SER A 176
ILE A 385
HIS A 448
 None
 0.89A 1yajF-1ac5A:
10.8		 1yajF-1ac5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b5t PROTEIN
(METHYLENETETRAHYDRO
FOLATE REDUCTASE)

(Escherichia
coli) 		PF02219
(MTHFR) 		4 SER A  57
LEU A 117
ILE A 181
HIS A 273
 None
FAD  A 395 (-4.0A)
FAD  A 395 ( 4.0A)
None
 0.93A 1yajF-1b5tA:
1.2		 1yajF-1b5tA:
19.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c7j PROTEIN
(PARA-NITROBENZYL
ESTERASE)

(Bacillus
subtilis) 		PF00135
(COesterase) 		4 GLY A 105
SER A 189
LEU A  67
HIS A 399
 None
 0.96A 1yajF-1c7jA:
43.0		 1yajF-1c7jA:
36.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eth TRIACYLGLYCEROL
ACYL-HYDROLASE

(Sus scrofa) 		PF00151
(Lipase)
PF01477
(PLAT) 		4 GLY A 309
SER A 274
LEU A 176
ILE A  90
 None
 0.94A 1yajF-1ethA:
9.0		 1yajF-1ethA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flz URACIL-DNA
GLYCOSYLASE

(Escherichia
coli) 		PF03167
(UDG) 		4 GLY A 109
SER A  78
LEU A 224
HIS A  73
 None
 0.86A 1yajF-1flzA:
0.8		 1yajF-1flzA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fw8 PHOSPHOGLYCERATE
KINASE

(Saccharomyces
cerevisiae) 		PF00162
(PGK) 		4 GLY A 298
SER A 319
LEU A 329
HIS A 317
 None
 0.97A 1yajF-1fw8A:
0.9		 1yajF-1fw8A:
23.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gz7 LIPASE 2

(Diutina rugosa) 		PF00135
(COesterase) 		4 GLY A 124
SER A 209
LEU A 304
HIS A 449
 None
 0.96A 1yajF-1gz7A:
39.0		 1yajF-1gz7A:
31.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hdi PHOSPHOGLYCERATE
KINASE

(Sus scrofa) 		PF00162
(PGK) 		4 GLY A 371
SER A 392
LEU A 402
HIS A 390
 None
 0.91A 1yajF-1hdiA:
undetectable		 1yajF-1hdiA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j0a 1-AMINOCYCLOPROPANE-
1-CARBOXYLATE
DEAMINASE

(Pyrococcus
horikoshii) 		PF00291
(PALP) 		4 LEU A 100
GLY A  88
ILE A 154
HIS A  83
 None
 0.97A 1yajF-1j0aA:
0.9		 1yajF-1j0aA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jkm BREFELDIN A ESTERASE

(Bacillus
subtilis) 		PF07859
(Abhydrolase_3) 		6 LEU A 132
GLY A 127
SER A 202
LEU A 268
ILE A 260
HIS A 338
 None
 1.35A 1yajF-1jkmA:
18.4		 1yajF-1jkmA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mor GLUCOSAMINE
6-PHOSPHATE SYNTHASE

(Escherichia
coli) 		PF01380
(SIS) 		4 LEU A 346
GLY A 307
SER A 310
ILE A 295
 None
 0.90A 1yajF-1morA:
undetectable		 1yajF-1morA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n3k ASTROCYTIC
PHOSPHOPROTEIN
PEA-15

(Cricetulus
griseus) 		PF01335
(DED) 		4 LEU A  20
GLY A  42
LEU A  11
ILE A  63
 None
 0.75A 1yajF-1n3kA:
undetectable		 1yajF-1n3kA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o9b HYPOTHETICAL
SHIKIMATE
5-DEHYDROGENASE-LIKE
PROTEIN YDIB

(Escherichia
coli) 		PF08501
(Shikimate_dh_N) 		5 LEU A 129
GLY A 140
LEU A 148
ILE A 115
HIS A 111
 None
 1.39A 1yajF-1o9bA:
undetectable		 1yajF-1o9bA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1otw COENZYME PQQ
SYNTHESIS PROTEIN C

(Klebsiella
pneumoniae) 		PF03070
(TENA_THI-4) 		4 LEU A 215
GLY A  20
ILE A  25
HIS A  26
 None
 0.83A 1yajF-1otwA:
undetectable		 1yajF-1otwA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qqf PROTEIN (COMPLEMENT
C3DG)

(Rattus
norvegicus) 		PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 LEU A1078
GLY A1011
ILE A1125
HIS A1126
 None
CSO  A1010 ( 2.5A)
None
CSO  A1010 ( 4.8A)
 0.76A 1yajF-1qqfA:
undetectable		 1yajF-1qqfA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6a GENOME POLYPROTEIN

(Dengue virus) 		PF01728
(FtsJ) 		4 GLY A  86
SER A  56
LEU A 126
ILE A 114
 SAH  A 887 (-3.3A)
SAH  A 887 ( 2.8A)
None
None
 0.96A 1yajF-1r6aA:
undetectable		 1yajF-1r6aA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tg5 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE

(Arabidopsis
thaliana) 		PF00903
(Glyoxalase) 		5 GLY A 184
SER A  55
LEU A 149
ILE A  99
HIS A  64
 None
 1.37A 1yajF-1tg5A:
undetectable		 1yajF-1tg5A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xd7 YWNA

(Bacillus
subtilis) 		PF02082
(Rrf2) 		4 GLY A  61
SER A  26
LEU A  53
ILE A  14
 SO4  A 190 (-3.4A)
SO4  A 190 (-2.4A)
None
None
 0.92A 1yajF-1xd7A:
undetectable		 1yajF-1xd7A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE

(Hevea
brasiliensis) 		PF00561
(Abhydrolase_1) 		4 LEU A 148
SER A  80
ILE A 209
HIS A 235
 MNN  A 300 (-4.3A)
MNN  A 300 (-2.5A)
MNN  A 300 (-4.4A)
MNN  A 300 (-4.2A)
 0.89A 1yajF-1yb6A:
9.3		 1yajF-1yb6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ydg TRP REPRESSOR
BINDING PROTEIN WRBA

(Deinococcus
radiodurans) 		PF03358
(FMN_red) 		4 GLY A  18
SER A  83
LEU A 176
ILE A 184
 SO4  A1302 (-3.6A)
None
None
None
 0.93A 1yajF-1ydgA:
undetectable		 1yajF-1ydgA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yw5 PEPTIDYL PROLYL
CIS/TRANS ISOMERASE

(Candida
albicans) 		PF00397
(WW)
PF00639
(Rotamase) 		4 LEU A  74
GLY A 169
SER A  80
ILE A  92
 None
 0.93A 1yajF-1yw5A:
undetectable		 1yajF-1yw5A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvt TOPOISOMERASE IV
SUBUNIT A

(Escherichia
coli) 		PF03989
(DNA_gyraseA_C) 		4 LEU A 660
GLY A 603
LEU A 689
ILE A 672
 None
 0.87A 1yajF-1zvtA:
undetectable		 1yajF-1zvtA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvu TOPOISOMERASE IV
SUBUNIT A

(Escherichia
coli) 		PF00521
(DNA_topoisoIV)
PF03989
(DNA_gyraseA_C) 		4 LEU A 660
GLY A 603
LEU A 689
ILE A 672
 None
 0.90A 1yajF-1zvuA:
undetectable		 1yajF-1zvuA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zy8 DIHYDROLIPOYL
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLY A 217
SER A 370
ILE A 222
HIS A 419
 None
 0.97A 1yajF-1zy8A:
undetectable		 1yajF-1zy8A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bc0 NADH OXIDASE

(Streptococcus
pyogenes) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 188
GLY A 172
LEU A 196
ILE A 342
 None
 0.96A 1yajF-2bc0A:
undetectable		 1yajF-2bc0A:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2czq CUTINASE-LIKE
PROTEIN

(Cryptococcus
sp. S-2) 		PF01083
(Cutinase) 		4 GLY A  16
SER A  85
ILE A 176
HIS A 180
 EDO  A 602 (-3.4A)
EDO  A 602 ( 3.9A)
EDO  A 602 ( 4.9A)
EDO  A 602 ( 4.8A)
 0.84A 1yajF-2czqA:
3.8		 1yajF-2czqA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4e 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
SEMIALDEHYDE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00171
(Aldedh) 		4 LEU A 272
GLY A 254
LEU A 268
ILE A 169
 None
None
None
GOL  A1801 (-4.1A)
 0.72A 1yajF-2d4eA:
undetectable		 1yajF-2d4eA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egz 3-DEHYDROQUINATE
DEHYDRATASE

(Aquifex
aeolicus) 		PF01487
(DHquinase_I) 		4 LEU A 157
GLY A 183
SER A 188
ILE A 170
 None
None
None
TLA  A4988 (-3.8A)
 0.97A 1yajF-2egzA:
undetectable		 1yajF-2egzA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fp7 GENOME POLYPROTEIN

(West Nile virus) 		PF00949
(Peptidase_S7) 		4 LEU B  49
GLY B 151
SER B 163
ILE B 139
 None
 0.72A 1yajF-2fp7B:
undetectable		 1yajF-2fp7B:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ia0 PUTATIVE HTH-TYPE
TRANSCRIPTIONAL
REGULATOR PF0864

(Pyrococcus
furiosus) 		PF13412
(HTH_24) 		4 LEU A  68
GLY A 117
LEU A 124
ILE A  71
 None
 0.91A 1yajF-2ia0A:
undetectable		 1yajF-2ia0A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipi ACLACINOMYCIN
OXIDOREDUCTASE
(AKNOX)

(Streptomyces
galilaeus) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 LEU A 140
GLY A 136
SER A  67
ILE A 202
 None
FAD  A 801 ( 4.0A)
FAD  A 801 (-2.7A)
FAD  A 801 ( 4.8A)
 0.89A 1yajF-2ipiA:
undetectable		 1yajF-2ipiA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6h GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF01380
(SIS)
PF13522
(GATase_6) 		4 LEU A 346
GLY A 307
SER A 310
ILE A 295
 None
 0.88A 1yajF-2j6hA:
undetectable		 1yajF-2j6hA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kig INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE II
ISOFORM

(Mus musculus) 		PF16776
(INPP5B_PH) 		4 LEU A  41
GLY A  28
ILE A  67
HIS A  62
 None
 0.79A 1yajF-2kigA:
undetectable		 1yajF-2kigA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ls7 ASTROCYTIC
PHOSPHOPROTEIN
PEA-15

(Mus musculus) 		PF01335
(DED) 		4 LEU A  20
GLY A  42
LEU A  11
ILE A  63
 None
 0.95A 1yajF-2ls7A:
undetectable		 1yajF-2ls7A:
13.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50

(Geobacillus
stearothermophilus) 		PF00135
(COesterase) 		4 LEU A 218
GLY A 201
LEU A 292
ILE A 300
 LEU  A 218 ( 0.6A)
GLY  A 201 ( 0.0A)
LEU  A 292 ( 0.6A)
ILE  A 300 ( 0.7A)
 0.96A 1yajF-2ogsA:
47.6		 1yajF-2ogsA:
35.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvp D-ALANINE-D-ALANINE
LIGASE

(Helicobacter
pylori) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		5 GLY A   8
SER A  17
LEU A 105
ILE A 304
HIS A  96
 None
 1.21A 1yajF-2pvpA:
undetectable		 1yajF-2pvpA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		4 LEU A 576
GLY A 677
SER A 674
ILE A 606
 None
 0.79A 1yajF-2w20A:
undetectable		 1yajF-2w20A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xqw COMPLEMENT C3

(Homo sapiens) 		PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 LEU A  85
GLY A  18
ILE A 132
HIS A 133
 None
 0.80A 1yajF-2xqwA:
undetectable		 1yajF-2xqwA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwb COMPLEMENT C3B
ALPHA' CHAIN

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 LEU B1056
GLY B 989
ILE B1103
HIS B1104
 None
 0.77A 1yajF-2xwbB:
undetectable		 1yajF-2xwbB:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayf NITRIC OXIDE
REDUCTASE

(Geobacillus
stearothermophilus) 		PF00115
(COX1) 		4 LEU A 672
SER A 313
LEU A 686
ILE A 665
 None
 0.69A 1yajF-3ayfA:
undetectable		 1yajF-3ayfA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cx6 GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-13
SUBUNIT

(Mus musculus) 		PF00503
(G-alpha) 		4 LEU A 170
GLY A  95
LEU A 178
ILE A 158
 None
 0.84A 1yajF-3cx6A:
undetectable		 1yajF-3cx6A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dl0 ADENYLATE KINASE

(Bacillus
subtilis) 		PF00406
(ADK)
PF05191
(ADK_lid) 		4 LEU A  82
GLY A  17
LEU A 208
ILE A 113
 None
 0.96A 1yajF-3dl0A:
undetectable		 1yajF-3dl0A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4t DIPHTHINE SYNTHASE

(Entamoeba
histolytica) 		PF00590
(TP_methylase) 		4 LEU A 124
GLY A 118
LEU A 249
ILE A 113
 None
 0.79A 1yajF-3i4tA:
undetectable		 1yajF-3i4tA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 LEU X 507
SER X 615
LEU X 517
ILE X 559
 None
 0.97A 1yajF-3jb9X:
undetectable		 1yajF-3jb9X:
17.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k9b LIVER
CARBOXYLESTERASE 1

(Homo sapiens) 		PF00135
(COesterase) 		4 GLY A1143
SER A1221
ILE A1359
HIS A1468
 WW2  A 193 (-3.4A)
WW2  A 193 (-1.4A)
WW2  A 193 ( 4.3A)
None
 0.84A 1yajF-3k9bA:
60.9		 1yajF-3k9bA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k9b LIVER
CARBOXYLESTERASE 1

(Homo sapiens) 		PF00135
(COesterase) 		5 LEU A1097
GLY A1142
SER A1221
ILE A1359
HIS A1468
 WW2  A 193 ( 4.9A)
WW2  A 193 (-3.4A)
WW2  A 193 (-1.4A)
WW2  A 193 ( 4.3A)
None
 0.37A 1yajF-3k9bA:
60.9		 1yajF-3k9bA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8d METHYLTRANSFERASE

(Bacillus
thuringiensis) 		PF08241
(Methyltransf_11) 		4 GLY A  61
SER A 125
LEU A  58
ILE A 139
 None
 0.84A 1yajF-3l8dA:
undetectable		 1yajF-3l8dA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pco PHENYLALANYL-TRNA
SYNTHETASE, BETA
CHAIN

(Escherichia
coli) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 LEU B 287
GLY B 319
SER B 322
ILE B 304
 None
 0.87A 1yajF-3pcoB:
undetectable		 1yajF-3pcoB:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxn KINESIN-LIKE PROTEIN
NOD

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 GLY A 252
SER A 275
LEU A 227
ILE A 144
 None
 0.94A 1yajF-3pxnA:
undetectable		 1yajF-3pxnA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rj8 CARBOHYDRATE OXIDASE

(Microdochium
nivale) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 LEU A 450
SER A 192
ILE A 426
HIS A 143
 None
FAD  A 501 (-4.0A)
None
FAD  A 501 (-4.8A)
 0.96A 1yajF-3rj8A:
undetectable		 1yajF-3rj8A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT L

(Escherichia
coli) 		no annotation 4 LEU L  18
GLY L  34
SER L  37
ILE L 124
 None
 0.96A 1yajF-3rkoL:
undetectable		 1yajF-3rkoL:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a1o BIFUNCTIONAL PURINE
BIOSYNTHESIS PROTEIN
PURH

(Mycobacterium
tuberculosis) 		PF01808
(AICARFT_IMPCHas)
PF02142
(MGS) 		4 LEU A 164
GLY A  29
LEU A  26
ILE A  37
 None
 0.96A 1yajF-4a1oA:
undetectable		 1yajF-4a1oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Cryptococcus
neoformans) 		PF00478
(IMPDH)
PF00571
(CBS) 		4 GLY B 105
SER B 250
LEU B  84
ILE B  77
 None
 0.86A 1yajF-4af0B:
undetectable		 1yajF-4af0B:
23.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4be9 STEROL ESTERASE

(Ophiostoma
piceae) 		PF00135
(COesterase) 		4 GLY A 133
SER A 220
LEU A 138
HIS A 465
 None
1PE  A1553 (-2.9A)
None
None
 0.85A 1yajF-4be9A:
40.3		 1yajF-4be9A:
32.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccy CARBOXYLESTERASE
YBFK

(Bacillus
subtilis) 		PF12697
(Abhydrolase_6) 		5 GLY B  63
SER B 130
LEU B  65
ILE B 186
HIS B 274
 None
 1.37A 1yajF-4ccyB:
7.2		 1yajF-4ccyB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4db3 N-ACETYL-D-GLUCOSAMI
NE KINASE

(Vibrio
vulnificus) 		PF00480
(ROK) 		4 LEU A 138
GLY A 153
LEU A 128
ILE A 240
 None
 0.83A 1yajF-4db3A:
undetectable		 1yajF-4db3A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dg5 PHOSPHOGLYCERATE
KINASE

(Staphylococcus
aureus) 		PF00162
(PGK) 		4 GLY A 351
SER A 372
LEU A 382
HIS A 370
 None
 0.92A 1yajF-4dg5A:
undetectable		 1yajF-4dg5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fiu HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 GLY A 247
SER A 245
LEU A 214
ILE A 181
 None
 0.95A 1yajF-4fiuA:
undetectable		 1yajF-4fiuA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hac MEVALONATE KINASE

(Methanosarcina
mazei) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 LEU A 239
GLY A 263
SER A  90
ILE A 165
 None
 0.82A 1yajF-4hacA:
undetectable		 1yajF-4hacA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imp POLYKETIDE SYNTHASE
EXTENDER MODULES 3-4

(Saccharopolyspora
spinosa) 		PF08659
(KR) 		4 LEU A 373
GLY A 423
LEU A 381
ILE A 164
 None
 0.95A 1yajF-4impA:
3.1		 1yajF-4impA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irt UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF15892
(BNR_4) 		5 LEU A 175
GLY A 152
LEU A 154
ILE A  97
HIS A  48
 None
 1.29A 1yajF-4irtA:
undetectable		 1yajF-4irtA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4obu PYRIDOXAL-DEPENDENT
DECARBOXYLASE DOMAIN
PROTEIN

([Ruminococcus]
gnavus) 		no annotation 4 GLY E 275
SER E 301
ILE E 243
HIS E 272
 None
 0.89A 1yajF-4obuE:
undetectable		 1yajF-4obuE:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ose PUTATIVE HYDROLASE

(Rickettsia
typhi) 		PF00561
(Abhydrolase_1) 		4 GLY A  44
SER A 112
ILE A 149
HIS A 269
 None
 0.93A 1yajF-4oseA:
11.2		 1yajF-4oseA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oyy CUTINASE

(Humicola
insolens) 		PF01083
(Cutinase) 		4 GLY A  27
SER A 105
ILE A 169
HIS A 173
 None
 0.90A 1yajF-4oyyA:
7.0		 1yajF-4oyyA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT

(Pseudomonas
aeruginosa) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		4 LEU A 286
GLY A 318
SER A 321
ILE A 303
 None
 0.82A 1yajF-4p72A:
undetectable		 1yajF-4p72A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psd CARBOHYDRATE
ESTERASE FAMILY 5

(Trichoderma
reesei) 		PF01083
(Cutinase) 		4 GLY A  89
SER A 164
ILE A 225
HIS A 229
 None
 0.81A 1yajF-4psdA:
5.1		 1yajF-4psdA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12265
(CAF1C_H4-bd) 		4 LEU B 257
GLY B 225
ILE B 211
HIS B 207
 None
 0.92A 1yajF-4pswB:
undetectable		 1yajF-4pswB:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q3l MGS-M2

(unidentified) 		PF00561
(Abhydrolase_1) 		4 GLY A  31
SER A  97
ILE A 157
HIS A 249
 None
 0.97A 1yajF-4q3lA:
12.9		 1yajF-4q3lA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r20 CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2

(Danio rerio) 		PF00067
(p450) 		4 LEU A 370
GLY A 434
ILE A 399
HIS A 400
 HEM  A 601 ( 4.1A)
HEM  A 601 (-4.0A)
None
None
 0.90A 1yajF-4r20A:
undetectable		 1yajF-4r20A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzl RESTRICTION
ENDONUCLEASE LPNPI

(Legionella
pneumophila) 		no annotation 4 LEU A   9
GLY A  22
SER A 138
ILE A   3
 None
 0.97A 1yajF-4rzlA:
undetectable		 1yajF-4rzlA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tv7 HTH-TYPE
TRANSCRIPTIONAL
REGULATORY PROTEIN
GABR

(Bacillus
subtilis) 		PF00155
(Aminotran_1_2)
PF00392
(GntR) 		4 LEU A 423
GLY A 460
LEU A 452
ILE A 447
 None
 0.94A 1yajF-4tv7A:
undetectable		 1yajF-4tv7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzj NOTUM

(Drosophila
melanogaster) 		PF03283
(PAE) 		4 GLY A 125
SER A 237
LEU A 145
HIS A 384
 None
 0.94A 1yajF-4uzjA:
10.2		 1yajF-4uzjA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjm RIBOKINASE:CARBOHYDR
ATE KINASE, PFKB

(Brucella
abortus) 		PF00294
(PfkB) 		4 LEU A 154
GLY A 126
ILE A 158
HIS A 169
 None
 0.93A 1yajF-4wjmA:
undetectable		 1yajF-4wjmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzo PUTATIVE ACYL-COA
ACYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 LEU A 131
GLY A 359
SER A  76
HIS A 320
 None
 0.78A 1yajF-4yzoA:
undetectable		 1yajF-4yzoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d2e MLNE

(Bacillus
velezensis) 		PF08659
(KR) 		4 LEU A 475
GLY A 480
LEU A 285
ILE A 447
 None
None
NAP  A 601 (-4.1A)
None
 0.89A 1yajF-5d2eA:
2.2		 1yajF-5d2eA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hs1 LANOSTEROL 14-ALPHA
DEMETHYLASE

(Saccharomyces
cerevisiae) 		PF00067
(p450) 		4 LEU A 366
GLY A 481
LEU A 355
ILE A 486
 None
 0.81A 1yajF-5hs1A:
undetectable		 1yajF-5hs1A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idk GENOME
POLYPROTEIN,SERINE
PROTEASE SUBUNIT
NS2B, SERINE
PROTEASE NS3

(West Nile virus) 		PF00949
(Peptidase_S7)
PF01002
(Flavi_NS2B) 		4 LEU A1049
GLY A1151
SER A1163
ILE A1139
 None
6A8  A1201 (-4.2A)
None
None
 0.69A 1yajF-5idkA:
undetectable		 1yajF-5idkA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5t MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE KINASE
3

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 210
GLY A 106
LEU A 108
ILE A 101
 None
 0.97A 1yajF-5j5tA:
undetectable		 1yajF-5j5tA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jlc LANOSTEROL 14-ALPHA
DEMETHYLASE

([Candida]
glabrata) 		PF00067
(p450) 		4 LEU A 367
GLY A 483
LEU A 356
ILE A 488
 None
 0.91A 1yajF-5jlcA:
undetectable		 1yajF-5jlcA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khn RND TRANSPORTER

(Burkholderia
multivorans) 		no annotation 4 GLY B 783
SER B 388
LEU B 752
ILE B 728
 None
 0.93A 1yajF-5khnB:
undetectable		 1yajF-5khnB:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kvc HALOHYDRIN
DEHALOGENASE

(Agrobacterium
tumefaciens) 		PF13561
(adh_short_C2) 		4 LEU A 178
GLY A  13
SER A  17
ILE A 173
 CL  A 301 (-4.3A)
EDO  A 305 ( 4.3A)
None
None
 0.93A 1yajF-5kvcA:
undetectable		 1yajF-5kvcA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzn METABOTROPIC
GLUTAMATE RECEPTOR 2

(Homo sapiens) 		PF01094
(ANF_receptor)
PF07562
(NCD3G) 		4 LEU A  37
LEU A 155
ILE A 136
HIS A  87
 None
 0.95A 1yajF-5kznA:
undetectable		 1yajF-5kznA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2p ARYLESTERASE

(Sulfolobus
solfataricus) 		PF07859
(Abhydrolase_3) 		4 GLY A  83
SER A 156
LEU A  88
HIS A 281
 None
 0.89A 1yajF-5l2pA:
17.6		 1yajF-5l2pA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2p ARYLESTERASE

(Sulfolobus
solfataricus) 		PF07859
(Abhydrolase_3) 		4 LEU A  38
GLY A  84
SER A 156
HIS A 281
 None
 0.90A 1yajF-5l2pA:
17.6		 1yajF-5l2pA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6f FAD LINKED
OXIDASE-LIKE PROTEIN

(Thermothelomyces
thermophila) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 LEU A 473
SER A 215
ILE A 449
HIS A 166
 None
FAD  A 501 (-4.1A)
None
FAD  A 501 (-4.6A)
 0.90A 1yajF-5l6fA:
undetectable		 1yajF-5l6fA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
4

(Bos taurus) 		PF00361
(Proton_antipo_M)
PF01059
(Oxidored_q5_N) 		4 LEU M  68
GLY M 320
SER M 324
HIS M 440
 None
 0.96A 1yajF-5lc5M:
undetectable		 1yajF-5lc5M:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5njl CELL SURFACE PROTEIN
(PUTATIVE S-LAYER
PROTEIN)

(Clostridioides
difficile) 		no annotation 4 LEU A 232
LEU A  50
ILE A  65
HIS A 108
 None
None
None
SO4  A 402 (-3.9A)
 0.93A 1yajF-5njlA:
undetectable		 1yajF-5njlA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE

(Rhizobium sp.
NT-26) 		no annotation 4 LEU A 474
SER A 166
ILE A 550
HIS A 489
 None
 0.97A 1yajF-5nqdA:
undetectable		 1yajF-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5the UNCHARACTERIZED
PROTEIN

(Vanderwaltozyma
polyspora) 		no annotation 4 GLY A 832
SER A 870
LEU A 905
ILE A 828
 None
 0.84A 1yajF-5theA:
undetectable		 1yajF-5theA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ul4 OXSB PROTEIN

(Bacillus
megaterium) 		PF02310
(B12-binding) 		4 LEU A 157
GLY A 141
SER A 145
LEU A 136
 None
 0.94A 1yajF-5ul4A:
4.0		 1yajF-5ul4A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ume 5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE

(Haemophilus
influenzae) 		PF02219
(MTHFR) 		4 SER A  55
LEU A 115
ILE A 179
HIS A 271
 None
FAD  A 300 (-3.9A)
FAD  A 300 (-4.0A)
None
 0.97A 1yajF-5umeA:
undetectable		 1yajF-5umeA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uyr BACTERIOPHYTOCHROME

(Xanthomonas
campestris) 		no annotation 4 LEU A 431
GLY A 402
ILE A 427
HIS A 405
 None
 0.92A 1yajF-5uyrA:
undetectable		 1yajF-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj7 OXIDOREDUCTASE

(Pyrococcus
furiosus) 		PF07992
(Pyr_redox_2)
PF14691
(Fer4_20) 		4 LEU A 207
GLY A 190
LEU A 167
ILE A 221
 None
 0.97A 1yajF-5vj7A:
undetectable		 1yajF-5vj7A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x1y MERCURIC REDUCTASE

(Lysinibacillus
sphaericus) 		no annotation 4 LEU B 277
GLY B 265
LEU B 342
ILE B 260
 None
None
None
FAD  B 601 ( 3.8A)
 0.91A 1yajF-5x1yB:
undetectable		 1yajF-5x1yB:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfp EXOCYST COMPLEX
COMPONENT EXO84

(Saccharomyces
cerevisiae) 		no annotation 4 SER H 723
LEU H 715
ILE H 705
HIS H 701
 None
 0.96A 1yajF-5yfpH:
undetectable		 1yajF-5yfpH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6avo PROTEASOME SUBUNIT
BETA TYPE-9

(Homo sapiens) 		no annotation 4 GLY A 171
SER A  18
LEU A 193
ILE A 159
 None
 0.96A 1yajF-6avoA:
undetectable		 1yajF-6avoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8z ADP-DEPENDENT
PHOSPHOFRUCTOKINASE

(Methanosarcinales) 		no annotation 4 GLY A 363
SER A 361
LEU A 422
ILE A 366
 None
 0.96A 1yajF-6c8zA:
undetectable		 1yajF-6c8zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6co0 STYRYLPYRONE
SYNTHASE 1

(Piper
methysticum) 		no annotation 4 LEU A 344
GLY A 167
LEU A 371
ILE A 240
 None
 0.97A 1yajF-6co0A:
undetectable		 1yajF-6co0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 LEU A2313
GLY A2334
LEU A2082
ILE A2059
 None
 0.82A 1yajF-6fb3A:
undetectable		 1yajF-6fb3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fg9 -

(-) 		no annotation 4 LEU A 163
GLY A 238
SER A 234
LEU A 194
 None
 0.98A 1yajF-6fg9A:
undetectable		 1yajF-6fg9A:
undetectable