SIMILAR PATTERNS OF AMINO ACIDS FOR 1YAJ_D_BEZD2385_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aos ARGININOSUCCINATE
LYASE

(Homo sapiens) 		PF00206
(Lyase_1)
PF14698
(ASL_C2) 		4 LEU A 373
LEU A 408
LEU A 410
LEU A 405
 None
 1.05A 1yajD-1aosA:
undetectable		 1yajD-1aosA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bbj IGG4-KAPPA B72.3 FAB
(HEAVY CHAIN)
IGG4-KAPPA B72.3 FAB
(LIGHT CHAIN)

(Homo sapiens;
Mus musculus;
Homo sapiens;
Mus musculus) 		no annotation
no annotation 		4 SER L 162
LEU H 125
LEU L 135
LEU H 142
 None
 1.13A 1yajD-1bbjL:
undetectable		 1yajD-1bbjL:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8c MALATE SYNTHASE G

(Escherichia
coli) 		PF01274
(Malate_synthase) 		4 SER A 463
LEU A  91
LEU A  88
LEU A 433
 None
 1.13A 1yajD-1d8cA:
2.4		 1yajD-1d8cA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1drt CLAVAMINATE SYNTHASE
1

(Streptomyces
clavuligerus) 		PF02668
(TauD) 		4 LEU A  46
LEU A  63
LEU A  64
LEU A  50
 None
 1.15A 1yajD-1drtA:
undetectable		 1yajD-1drtA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyd ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE A

(Cellvibrio
japonicus) 		PF04616
(Glyco_hydro_43) 		4 LEU B 321
LEU B 251
LEU B 278
LEU B 305
 None
 0.93A 1yajD-1gydB:
undetectable		 1yajD-1gydB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3b ATP-DEPENDENT
PHOSPHOENOLPYRUVATE
CARBOXYKINASE

(Thermus
thermophilus) 		PF01293
(PEPCK_ATP) 		4 LEU A 423
SER A 370
LEU A 233
LEU A 353
 None
 1.03A 1yajD-1j3bA:
0.0		 1yajD-1j3bA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jih DNA POLYMERASE ETA

(Saccharomyces
cerevisiae) 		PF00817
(IMS)
PF11799
(IMS_C) 		4 LEU A 370
SER A 360
LEU A 320
LEU A 346
 None
 1.14A 1yajD-1jihA:
undetectable		 1yajD-1jihA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5a AMIDE SYNTHASE

(Vibrio cholerae) 		PF00668
(Condensation) 		4 LEU A 226
LEU A 219
LEU A 374
LEU A 404
 None
 1.12A 1yajD-1l5aA:
undetectable		 1yajD-1l5aA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 186
LEU A 174
LEU A 170
LEU A 261
 None
 1.01A 1yajD-1lvlA:
undetectable		 1yajD-1lvlA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m72 CASPASE-1

(Spodoptera
frugiperda) 		PF00656
(Peptidase_C14) 		4 LEU A 236
LEU A 252
LEU A 250
LEU A 240
 None
 0.95A 1yajD-1m72A:
3.2		 1yajD-1m72A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n1q DPS PROTEIN

(Brevibacillus
brevis) 		PF00210
(Ferritin) 		4 LEU A  23
SER A  99
LEU A 137
LEU A 107
 None
 1.12A 1yajD-1n1qA:
undetectable		 1yajD-1n1qA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nty TRIPLE FUNCTIONAL
DOMAIN PROTEIN

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 LEU A1498
LEU A1450
LEU A1429
LEU A1512
 None
 1.06A 1yajD-1ntyA:
undetectable		 1yajD-1ntyA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1puj CONSERVED
HYPOTHETICAL PROTEIN
YLQF

(Bacillus
subtilis) 		PF01926
(MMR_HSR1) 		4 LEU A  56
SER A 100
LEU A  93
LEU A 136
 None
 0.89A 1yajD-1pujA:
undetectable		 1yajD-1pujA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfx PROTEIN (PH 2.5 ACID
PHOSPHATASE)

(Aspergillus
niger) 		PF00328
(His_Phos_2) 		4 LEU A 329
SER A 298
LEU A 404
LEU A 382
 None
 1.12A 1yajD-1qfxA:
undetectable		 1yajD-1qfxA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sw6 REGULATORY PROTEIN
SWI6

(Saccharomyces
cerevisiae) 		PF00023
(Ank)
PF13857
(Ank_5) 		4 LEU A 250
SER A 342
LEU A 296
LEU A 254
 None
 1.08A 1yajD-1sw6A:
undetectable		 1yajD-1sw6A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sw6 REGULATORY PROTEIN
SWI6

(Saccharomyces
cerevisiae) 		PF00023
(Ank)
PF13857
(Ank_5) 		4 LEU A 415
LEU A 355
LEU A 383
LEU A 374
 None
 1.16A 1yajD-1sw6A:
undetectable		 1yajD-1sw6A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wsv AMINOMETHYLTRANSFERA
SE

(Homo sapiens) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 LEU A 144
LEU A  57
LEU A 102
LEU A 125
 LEU  A 144 ( 0.6A)
LEU  A  57 ( 0.6A)
LEU  A 102 (-0.6A)
LEU  A 125 ( 0.6A)
 1.10A 1yajD-1wsvA:
undetectable		 1yajD-1wsvA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wwl MONOCYTE
DIFFERENTIATION
ANTIGEN CD14

(Mus musculus) 		no annotation 4 LEU A 128
LEU A 142
LEU A 164
LEU A 145
 None
 1.11A 1yajD-1wwlA:
undetectable		 1yajD-1wwlA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz8 ENOYL-COA HYDRATASE

(Thermus
thermophilus) 		PF00378
(ECH_1) 		4 LEU A  60
LEU A  12
LEU A   5
LEU A  42
 None
 0.98A 1yajD-1wz8A:
undetectable		 1yajD-1wz8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1b CRTF-RELATED PROTEIN

(Chlorobaculum
tepidum) 		PF00891
(Methyltransf_2) 		4 LEU A 167
SER A 196
LEU A 161
LEU A 271
 None
 1.05A 1yajD-1x1bA:
2.7		 1yajD-1x1bA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y4u CHAPERONE PROTEIN
HTPG

(Escherichia
coli) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 LEU A 348
LEU A 299
LEU A 324
LEU A 330
 None
 0.84A 1yajD-1y4uA:
undetectable		 1yajD-1y4uA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3v SITE-SPECIFIC
RECOMBINASE INTI4

(Vibrio cholerae) 		PF00589
(Phage_integrase)
PF13495
(Phage_int_SAM_4) 		4 LEU A  54
LEU A  87
LEU A  89
LEU A  75
 None
 1.14A 1yajD-2a3vA:
undetectable		 1yajD-2a3vA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cdq ASPARTOKINASE

(Arabidopsis
thaliana) 		PF00696
(AA_kinase) 		4 LEU A 478
LEU A 332
LEU A 488
LEU A 425
 None
 0.96A 1yajD-2cdqA:
undetectable		 1yajD-2cdqA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gdr GLUTATHIONE
S-TRANSFERASE

(Paraburkholderia
xenovorans) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 LEU A  98
SER A  13
LEU A 146
LEU A 151
 None
 1.17A 1yajD-2gdrA:
undetectable		 1yajD-2gdrA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gfp MULTIDRUG RESISTANCE
PROTEIN D

(Escherichia
coli) 		PF07690
(MFS_1) 		4 LEU A 302
LEU A 365
LEU A 367
LEU A 220
 None
 1.05A 1yajD-2gfpA:
undetectable		 1yajD-2gfpA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq0 CHAPERONE PROTEIN
HTPG

(Escherichia
coli) 		PF00183
(HSP90) 		4 LEU A 348
LEU A 299
LEU A 324
LEU A 330
 None
 0.87A 1yajD-2gq0A:
undetectable		 1yajD-2gq0A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i62 NICOTINAMIDE
N-METHYLTRANSFERASE

(Mus musculus) 		PF01234
(NNMT_PNMT_TEMT) 		4 SER A  85
LEU A  59
LEU A  60
LEU A 155
 None
 1.11A 1yajD-2i62A:
undetectable		 1yajD-2i62A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iop CHAPERONE PROTEIN
HTPG

(Escherichia
coli) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 LEU A 348
LEU A 299
LEU A 324
LEU A 330
 None
 0.86A 1yajD-2iopA:
undetectable		 1yajD-2iopA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ps2 PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Aspergillus
oryzae) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 201
LEU A 210
LEU A 212
LEU A 221
 None
 1.14A 1yajD-2ps2A:
undetectable		 1yajD-2ps2A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pvc DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3-LIKE

(Homo sapiens) 		no annotation 4 LEU B 346
LEU B 248
LEU B 355
LEU B 288
 None
 0.70A 1yajD-2pvcB:
undetectable		 1yajD-2pvcB:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8h [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 LEU A  83
SER A  75
LEU A  57
LEU A 195
 None
 1.09A 1yajD-2q8hA:
undetectable		 1yajD-2q8hA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ru4 ARMADILLO REPEAT
PROTEIN, N-TERMINAL
FRAGMENT, YIIM2
ARMADILLO REPEAT
PROTEIN, C-TERMINAL
FRAGMENT, MAII

(synthetic
construct;
synthetic
construct) 		PF00514
(Arm)
PF00514
(Arm)
PF16186
(Arm_3) 		4 LEU B 132
LEU A  94
LEU A  90
LEU B 135
 None
 0.95A 1yajD-2ru4B:
undetectable		 1yajD-2ru4B:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9t ROUNDABOUT HOMOLOG 1
SLIT HOMOLOG 2
PROTEIN N-PRODUCT

(Homo sapiens;
Homo sapiens) 		PF13927
(Ig_3)
PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		4 SER A 117
LEU A 122
LEU A 127
LEU B 400
 None
 1.13A 1yajD-2v9tA:
undetectable		 1yajD-2v9tA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2va8 SKI2-TYPE HELICASE

(Sulfolobus
solfataricus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 LEU A 300
SER A 601
LEU A 322
LEU A 286
 None
 1.07A 1yajD-2va8A:
2.2		 1yajD-2va8A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5l TYLACTONE SYNTHASE
STARTER MODULE AND
MODULES 1 & 2

(Streptomyces
fradiae) 		PF08659
(KR) 		4 LEU A 107
LEU A  59
LEU A  31
LEU A  74
 None
 1.08A 1yajD-2z5lA:
3.4		 1yajD-2z5lA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvi 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE

(Bacillus
subtilis) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 LEU A  95
LEU A 286
LEU A 288
LEU A 110
 None
 1.14A 1yajD-2zviA:
undetectable		 1yajD-2zviA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvi 2,3-DIKETO-5-METHYLT
HIOPENTYL-1-PHOSPHAT
E ENOLASE

(Bacillus
subtilis) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 LEU A 224
LEU A 239
LEU A 240
LEU A 254
 None
 1.15A 1yajD-2zviA:
undetectable		 1yajD-2zviA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9p CG5977-PA, ISOFORM A

(Drosophila
melanogaster) 		PF00004
(AAA)
PF09336
(Vps4_C) 		4 LEU A 679
SER A 730
LEU A 664
LEU A 671
 None
 1.17A 1yajD-3b9pA:
2.7		 1yajD-3b9pA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Mus musculus) 		PF05889
(SepSecS) 		4 LEU A  55
SER A 328
LEU A 121
LEU A 320
 None
None
None
EDO  A 502 (-3.9A)
 0.98A 1yajD-3bc8A:
2.4		 1yajD-3bc8A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxo N,N-DIMETHYLTRANSFER
ASE

(Streptomyces
venezuelae) 		PF13649
(Methyltransf_25) 		4 LEU A 112
SER A 124
LEU A  68
LEU A  66
 None
None
SAM  A 238 (-3.9A)
None
 1.02A 1yajD-3bxoA:
undetectable		 1yajD-3bxoA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c7j TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY

(Pseudomonas
syringae group
genomosp. 3) 		PF00392
(GntR)
PF07729
(FCD) 		4 LEU A 211
LEU A 151
LEU A 149
LEU A 195
 None
 1.03A 1yajD-3c7jA:
undetectable		 1yajD-3c7jA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3crr TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE

(Pseudomonas
aeruginosa) 		PF01715
(IPPT) 		4 LEU A  21
LEU A  98
LEU A  29
LEU A  10
 None
 0.83A 1yajD-3crrA:
undetectable		 1yajD-3crrA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fk4 RUBISCO-LIKE PROTEIN

(Bacillus cereus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 LEU A  93
LEU A 284
LEU A 286
LEU A 108
 None
 1.14A 1yajD-3fk4A:
undetectable		 1yajD-3fk4A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fk4 RUBISCO-LIKE PROTEIN

(Bacillus cereus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 LEU A 222
LEU A 237
LEU A 238
LEU A 252
 None
 1.14A 1yajD-3fk4A:
undetectable		 1yajD-3fk4A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhd FATTY ACID SYNTHASE

(Homo sapiens) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A 510
LEU A 815
LEU A 423
LEU A 566
 None
 1.11A 1yajD-3hhdA:
undetectable		 1yajD-3hhdA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hv1 POLAR AMINO ACID ABC
UPTAKE TRANSPORTER
SUBSTRATE BINDING
PROTEIN

(Streptococcus
thermophilus) 		PF00497
(SBP_bac_3) 		4 LEU A 213
LEU A 202
LEU A 134
LEU A 191
 None
 1.15A 1yajD-3hv1A:
undetectable		 1yajD-3hv1A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuu PUTATIVE
METALLOPEPTIDASE

(Chelativorans
sp. BNC1) 		PF07171
(MlrC_C)
PF07364
(DUF1485) 		4 LEU A 119
SER A  64
LEU A 135
LEU A 103
 None
 1.16A 1yajD-3iuuA:
3.2		 1yajD-3iuuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k5p D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Brucella
abortus) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A  66
LEU A  17
LEU A  16
LEU A  48
 None
 1.16A 1yajD-3k5pA:
3.2		 1yajD-3k5pA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lec NADB-ROSSMANN
SUPERFAMILY PROTEIN

(Streptococcus
agalactiae) 		PF04816
(TrmK) 		4 LEU A  22
SER A  27
LEU A  37
LEU A  36
 None
 1.04A 1yajD-3lecA:
3.2		 1yajD-3lecA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mmp RNA-DIRECTED RNA
POLYMERASE BETA
CHAIN

(Escherichia
virus Qbeta) 		no annotation 4 LEU G 291
SER G 338
LEU G 240
LEU G 331
 None
 1.16A 1yajD-3mmpG:
undetectable		 1yajD-3mmpG:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npe 9-CIS-EPOXYCAROTENOI
D DIOXYGENASE 1,
CHLOROPLASTIC

(Zea mays) 		PF03055
(RPE65) 		4 LEU A 139
SER A 583
LEU A 565
LEU A 180
 None
 1.14A 1yajD-3npeA:
undetectable		 1yajD-3npeA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyq MALONYL-COA LIGASE

(Streptomyces
coelicolor) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 164
LEU A   4
LEU A   8
LEU A 160
 None
 0.99A 1yajD-3nyqA:
undetectable		 1yajD-3nyqA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3og4 INTERLEUKIN-29

(Homo sapiens) 		PF15177
(IL28A) 		4 LEU A 154
SER A  30
LEU A  38
LEU A  83
 None
 1.06A 1yajD-3og4A:
undetectable		 1yajD-3og4A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		4 LEU A 120
LEU A  76
LEU A  77
LEU A 124
 None
 1.17A 1yajD-3p9uA:
undetectable		 1yajD-3p9uA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6h ENOYL-COA HYDRATASE,
ECHA3

(Mycobacterium
marinum) 		PF00378
(ECH_1) 		4 LEU A  34
SER A  59
LEU A  89
LEU A  85
 None
 1.05A 1yajD-3r6hA:
undetectable		 1yajD-3r6hA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rip GAMMA-TUBULIN
COMPLEX COMPONENT 4

(Homo sapiens) 		PF04130
(Spc97_Spc98) 		4 LEU A 104
LEU A  48
LEU A  25
LEU A 126
 None
 1.05A 1yajD-3ripA:
undetectable		 1yajD-3ripA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT J
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT K
NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT N

(Escherichia
coli;
Escherichia
coli;
Escherichia
coli) 		no annotation
no annotation
no annotation 		4 LEU K  68
LEU N 130
LEU N 128
LEU J 147
 None
 0.89A 1yajD-3rkoK:
undetectable		 1yajD-3rkoK:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s84 APOLIPOPROTEIN A-IV

(Homo sapiens) 		PF01442
(Apolipoprotein) 		4 LEU A 238
SER A 222
LEU A 329
LEU A 325
 None
 1.08A 1yajD-3s84A:
undetectable		 1yajD-3s84A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tkn NUCLEOPORIN NUP82

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 216
LEU A 223
LEU A 225
LEU A 259
 None
 0.97A 1yajD-3tknA:
undetectable		 1yajD-3tknA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Corynebacterium
glutamicum) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 LEU A 108
LEU A 130
LEU A  61
LEU A 112
 None
 1.15A 1yajD-3tx8A:
undetectable		 1yajD-3tx8A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5n PUTATIVE
RHAMNOSIDASE

(Streptomyces
avermitilis) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 SER A 767
LEU A 817
LEU A 823
LEU A 852
 None
 0.91A 1yajD-3w5nA:
undetectable		 1yajD-3w5nA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af3 AURORA KINASE B

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 262
LEU A 214
LEU A 207
LEU A 184
 None
None
VX6  A 500 (-4.6A)
None
 1.14A 1yajD-4af3A:
undetectable		 1yajD-4af3A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6w CLBP PEPTIDASE

(Escherichia
coli) 		PF00144
(Beta-lactamase) 		4 LEU A 171
SER A 148
LEU A 194
LEU A 158
 None
 1.16A 1yajD-4e6wA:
undetectable		 1yajD-4e6wA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emk U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM5

(Schizosaccharomyces
pombe) 		PF01423
(LSM) 		4 LEU A  73
LEU A  44
LEU A  64
LEU A  19
 None
 1.07A 1yajD-4emkA:
undetectable		 1yajD-4emkA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 14

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		4 SER N 240
LEU N 273
LEU N 271
LEU N 223
 None
 0.91A 1yajD-4heaN:
undetectable		 1yajD-4heaN:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k05 CONSERVED
HYPOTHETICAL
EXPORTED PROTEIN

(Bacteroides
fragilis) 		PF07075
(DUF1343) 		4 LEU A  60
SER A  73
LEU A 116
LEU A  86
 None
 1.16A 1yajD-4k05A:
undetectable		 1yajD-4k05A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8j L-CARNITINE/GAMMA-BU
TYROBETAINE
ANTIPORTER

(Proteus
mirabilis) 		PF02028
(BCCT) 		4 LEU A 105
LEU A 270
LEU A 268
LEU A 366
 None
 1.13A 1yajD-4m8jA:
undetectable		 1yajD-4m8jA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mrq PHOSPHOMANNOMUTASE/P
HOSPHOGLUCOMUTASE

(Pseudomonas
aeruginosa) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 LEU A 429
SER A 384
LEU A 392
LEU A 452
 None
 0.97A 1yajD-4mrqA:
undetectable		 1yajD-4mrqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nas RIBULOSE-BISPHOSPHAT
E CARBOXYLASE

(Alicyclobacillus
acidocaldarius) 		PF00016
(RuBisCO_large) 		4 LEU A 223
LEU A 238
LEU A 239
LEU A 253
 None
None
KCX  A 175 ( 4.4A)
None
 1.11A 1yajD-4nasA:
undetectable		 1yajD-4nasA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7z CELL DIVISION
CONTROL PROTEIN 21

(Pyrococcus
furiosus) 		PF00493
(MCM) 		4 LEU A 871
LEU A 304
LEU A 302
LEU A 344
 None
 1.05A 1yajD-4r7zA:
undetectable		 1yajD-4r7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa9 GALA PROTEIN TYPE 1,
3 OR 4

(Legionella
pneumophila) 		PF13516
(LRR_6) 		4 LEU A 157
SER A 137
LEU A 187
LEU A 166
 None
 1.15A 1yajD-4xa9A:
undetectable		 1yajD-4xa9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z61 PHYTOSULFOKINE
RECEPTOR 1

(Daucus carota) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 LEU A 445
LEU A 475
LEU A 453
LEU A 469
 None
 1.06A 1yajD-4z61A:
undetectable		 1yajD-4z61A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdl O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Homo sapiens) 		PF05889
(SepSecS) 		4 LEU A  55
SER A 328
LEU A 121
LEU A 320
 None
 0.95A 1yajD-4zdlA:
3.5		 1yajD-4zdlA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0l FIBRONECTIN-BINDING
PROTEIN

(Streptococcus
pyogenes) 		PF08341
(TED) 		4 LEU A 250
SER A 169
LEU A 231
LEU A 160
 None
 0.86A 1yajD-5a0lA:
undetectable		 1yajD-5a0lA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE

(Escherichia
coli) 		no annotation 4 LEU A  12
SER A  79
LEU A  68
LEU A   6
 None
 1.03A 1yajD-5c5zA:
undetectable		 1yajD-5c5zA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c77 PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1

(Saccharomyces
cerevisiae) 		PF04252
(RNA_Me_trans) 		4 LEU A 120
SER A  35
LEU A  75
LEU A  82
 None
 0.97A 1yajD-5c77A:
undetectable		 1yajD-5c77A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e26 PANTOTHENATE KINASE
2, MITOCHONDRIAL

(Homo sapiens) 		PF03630
(Fumble) 		4 LEU A 564
SER A 351
LEU A 282
LEU A 275
 None
 1.03A 1yajD-5e26A:
2.6		 1yajD-5e26A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eef HDAC6

(Danio rerio) 		PF00850
(Hist_deacetyl) 		4 LEU A 343
LEU A 305
LEU A 303
LEU A 347
 None
 1.16A 1yajD-5eefA:
undetectable		 1yajD-5eefA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g3f THERMUS THERMOPHILUS
MULTICOPPER OXIDASE

(Thermus
thermophilus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 176
LEU A 283
LEU A 213
LEU A 235
 None
 0.95A 1yajD-5g3fA:
undetectable		 1yajD-5g3fA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gm2 O-METHYLRANSFERASE

(Streptomyces
blastmyceticus) 		PF08241
(Methyltransf_11) 		4 SER A 154
LEU A 178
LEU A 177
LEU A  69
 SAH  A 301 (-4.4A)
None
None
None
 1.08A 1yajD-5gm2A:
undetectable		 1yajD-5gm2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpd STEROL REGULATORY
ELEMENT-BINDING
PROTEIN 1

(Schizosaccharomyces
pombe) 		PF09427
(DUF2014) 		4 LEU A 793
SER A 685
LEU A 829
LEU A 744
 None
 0.96A 1yajD-5gpdA:
undetectable		 1yajD-5gpdA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7w VENOM
5'-NUCLEOTIDASE

(Naja atra) 		no annotation 4 LEU A 432
LEU A 425
LEU A 424
LEU A 512
 None
 1.11A 1yajD-5h7wA:
3.2		 1yajD-5h7wA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxk ZINC-DEPENDENT
PEPTIDASE

(Thermus
thermophilus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 LEU A 104
SER A  76
LEU A  67
LEU A  63
 LEU  A 104 ( 0.6A)
SER  A  76 ( 0.0A)
LEU  A  67 ( 0.5A)
LEU  A  63 ( 0.5A)
 1.16A 1yajD-5hxkA:
undetectable		 1yajD-5hxkA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ipn RNA POLYMERASE SIGMA
FACTOR RPOS

(Escherichia
coli) 		PF00140
(Sigma70_r1_2)
PF04539
(Sigma70_r3)
PF04542
(Sigma70_r2)
PF04545
(Sigma70_r4) 		4 LEU F 313
LEU F 274
LEU F 280
LEU F 266
 None
 0.94A 1yajD-5ipnF:
2.2		 1yajD-5ipnF:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5it1 PUTATIVE CYTOCHROME
P450

(Streptomyces
peucetius) 		PF00067
(p450) 		4 LEU A 102
LEU A 227
LEU A 193
LEU A 212
 None
 0.86A 1yajD-5it1A:
undetectable		 1yajD-5it1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 4 LEU A  65
LEU A  51
LEU A  49
LEU A  60
 None
 0.95A 1yajD-5nd1A:
undetectable		 1yajD-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o4g RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-2

(Homo sapiens) 		no annotation 4 LEU C  24
LEU C  38
LEU C  63
LEU C  52
 None
 1.06A 1yajD-5o4gC:
undetectable		 1yajD-5o4gC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogl UNDECAPRENYL-DIPHOSP
HOOLIGOSACCHARIDE--P
ROTEIN
GLYCOTRANSFERASE

(Campylobacter
lari) 		no annotation 4 LEU A 687
SER A 669
LEU A 673
LEU A 661
 None
 1.02A 1yajD-5oglA:
undetectable		 1yajD-5oglA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj1 DNA TOPOISOMERASE 1

(Mycobacterium
tuberculosis) 		no annotation 4 LEU A 289
LEU A 504
LEU A 222
LEU A 284
 None
 1.14A 1yajD-5uj1A:
2.8		 1yajD-5uj1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj7 ORIGIN RECOGNITION
COMPLEX SUBUNIT 4
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5

(Homo sapiens;
Homo sapiens) 		PF13191
(AAA_16)
PF14629
(ORC4_C)
PF13191
(AAA_16)
PF14630
(ORC5_C) 		4 LEU E 177
SER E  16
LEU C 285
LEU C 308
 None
 1.10A 1yajD-5uj7E:
2.3		 1yajD-5uj7E:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v72 NADPH-DEPENDENT
GLYOXYLATE/HYDROXYPY
RUVATE REDUCTASE

(Sinorhizobium
meliloti) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A 161
LEU A 109
LEU A 107
LEU A 140
 None
 1.03A 1yajD-5v72A:
2.3		 1yajD-5v72A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vhi 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 8

(Homo sapiens) 		PF00004
(AAA) 		4 LEU d 119
LEU d 103
LEU d 107
LEU d 122
 None
 1.04A 1yajD-5vhid:
undetectable		 1yajD-5vhid:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtk CRISPR-ASSOCIATED
ENDORIBONUCLEASE
C2C2

(Leptotrichia
shahii) 		no annotation 4 LEU A 792
LEU A 683
LEU A 681
LEU A 785
 None
 1.01A 1yajD-5wtkA:
undetectable		 1yajD-5wtkA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 LEU A 384
LEU A 393
LEU A 363
LEU A 396
 None
 1.05A 1yajD-5y3jA:
undetectable		 1yajD-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yud BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 1E

(Mus musculus) 		no annotation 4 LEU A 547
LEU A 494
LEU A 486
LEU A 462
 None
 1.05A 1yajD-5yudA:
undetectable		 1yajD-5yudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zln TOLL-LIKE RECEPTOR 9

(Mus musculus) 		no annotation 4 LEU A 384
LEU A 393
LEU A 363
LEU A 396
 None
 1.06A 1yajD-5zlnA:
undetectable		 1yajD-5zlnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvs PUTATIVE CORE
PROTEIN NTPASE/VP5

(Aquareovirus C) 		no annotation 4 LEU 4 685
LEU 4 674
LEU 4 652
LEU 4 676
 None
 1.02A 1yajD-5zvs4:
undetectable		 1yajD-5zvs4:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az6 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptococcus
agalactiae) 		no annotation 4 LEU A  28
LEU A  16
LEU A  18
LEU A  34
 None
 1.12A 1yajD-6az6A:
undetectable		 1yajD-6az6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cmz DIHYDROLIPOYL
DEHYDROGENASE

(Burkholderia
cenocepacia) 		no annotation 4 LEU A 190
LEU A 178
LEU A 174
LEU A 266
 None
 1.01A 1yajD-6cmzA:
undetectable		 1yajD-6cmzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5o POLYMERASE BASIC
PROTEIN 2

(Influenza B
virus) 		no annotation 4 LEU C 330
SER C 407
LEU C 447
LEU C 399
 None
 0.92A 1yajD-6f5oC:
undetectable		 1yajD-6f5oC:
undetectable