SIMILAR PATTERNS OF AMINO ACIDS FOR 1YAJ_B_BEZB12_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awb MYO-INOSITOL
MONOPHOSPHATASE

(Homo sapiens) 		PF00459
(Inositol_P) 		4 GLY A 215
SER A 165
VAL A 175
LEU A 271
 None
IPD  A 281 ( 3.8A)
None
None
 1.36A 1yajB-1awbA:
undetectable		 1yajB-1awbA:
22.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		4 GLY A 444
SER A 336
VAL A 331
LEU A 437
 None
 0.99A 1yajB-1b41A:
45.7		 1yajB-1b41A:
36.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brl BACTERIAL LUCIFERASE

(Vibrio harveyi) 		PF00296
(Bac_luciferase) 		4 GLY A  28
SER A  31
VAL A  71
LEU A  24
 None
 1.37A 1yajB-1brlA:
undetectable		 1yajB-1brlA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 GLY A 444
SER A 336
VAL A 331
LEU A 437
 None
 1.11A 1yajB-1c2oA:
45.3		 1yajB-1c2oA:
36.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4o MALTODEXTRIN
PHOSPHORYLASE

(Escherichia
coli) 		PF00343
(Phosphorylase) 		4 GLY A 731
SER A 729
VAL A 740
LEU A 707
 None
 1.28A 1yajB-1e4oA:
1.8		 1yajB-1e4oA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e9y UREASE SUBUNIT ALPHA
UREASE SUBUNIT BETA

(Helicobacter
pylori;
Helicobacter
pylori) 		PF00547
(Urease_gamma)
PF00699
(Urease_beta)
PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 GLY A  73
SER A  76
VAL A  70
LEU B 565
 None
 1.25A 1yajB-1e9yA:
undetectable		 1yajB-1e9yA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ffv CUTL, MOLYBDOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE

(Hydrogenophaga
pseudoflava) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 GLY B 273
SER B 236
VAL B 245
LEU B  95
 None
 1.22A 1yajB-1ffvB:
undetectable		 1yajB-1ffvB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN

(Escherichia
coli) 		PF00005
(ABC_tran) 		4 GLY A 502
SER A 506
VAL A 682
LEU A 701
 None
SO4  A 708 (-3.0A)
None
None
 1.17A 1yajB-1mt0A:
undetectable		 1yajB-1mt0A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qjs HEMOPEXIN

(Oryctolagus
cuniculus) 		PF00045
(Hemopexin) 		4 GLY A 224
SER A 267
VAL A 249
LEU A 234
 None
 0.83A 1yajB-1qjsA:
undetectable		 1yajB-1qjsA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qo4 PEROXIDASE

(Arabidopsis
thaliana) 		PF00141
(peroxidase) 		4 GLY A  33
SER A  35
VAL A  79
LEU A  26
 None
HEM  A 374 (-2.8A)
None
None
 1.32A 1yajB-1qo4A:
undetectable		 1yajB-1qo4A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs0 2-OXOISOVALERATE
DEHYDROGENASE
BETA-SUBUNIT

(Pseudomonas
putida) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 GLY B 270
SER B 224
VAL B 336
LEU B 300
 None
 1.17A 1yajB-1qs0B:
undetectable		 1yajB-1qs0B:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		4 GLY A 334
SER A 642
VAL A 646
LEU A 771
 None
 1.32A 1yajB-1r8wA:
undetectable		 1yajB-1r8wA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		4 GLY B 226
SER B 203
VAL B 175
LEU B 230
 None
 1.17A 1yajB-1tnuB:
undetectable		 1yajB-1tnuB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc4 INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE

(Thermus
thermophilus) 		PF00218
(IGPS) 		4 GLY A 216
SER A 238
VAL A 233
LEU A 192
 SO4  A2001 (-3.8A)
None
None
None
 1.10A 1yajB-1vc4A:
undetectable		 1yajB-1vc4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhk HYPOTHETICAL PROTEIN
YQEU

(Bacillus
subtilis) 		PF04452
(Methyltrans_RNA) 		4 GLY A  86
SER A 116
VAL A 154
LEU A  93
 None
 1.37A 1yajB-1vhkA:
undetectable		 1yajB-1vhkA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]

(Escherichia
coli) 		PF13522
(GATase_6) 		4 GLY A   2
SER A 191
VAL A  96
LEU A  20
 None
 1.03A 1yajB-1xfgA:
undetectable		 1yajB-1xfgA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfu CALMODULIN-SENSITIVE
ADENYLATE CYCLASE

(Bacillus
anthracis) 		PF03497
(Anthrax_toxA)
PF07737
(ATLF) 		4 GLY A 362
SER A 354
VAL A 476
LEU A 338
 None
 1.34A 1yajB-1xfuA:
undetectable		 1yajB-1xfuA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asb TRANSCRIPTION
ELONGATION PROTEIN
NUSA

(Mycobacterium
tuberculosis) 		PF13184
(KH_5) 		4 GLY A 144
SER A 142
VAL A 170
LEU A 181
 None
 1.17A 1yajB-2asbA:
undetectable		 1yajB-2asbA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF03971
(IDH) 		4 GLY A  44
SER A  41
VAL A 127
LEU A  98
 None
 1.29A 1yajB-2b0tA:
undetectable		 1yajB-2b0tA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bkx GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Bacillus
subtilis) 		PF01182
(Glucosamine_iso) 		4 GLY A  33
SER A 190
VAL A 120
LEU A  66
 None
None
None
F6R  A1243 (-4.0A)
 1.22A 1yajB-2bkxA:
undetectable		 1yajB-2bkxA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bnh RIBONUCLEASE
INHIBITOR

(Sus scrofa) 		PF13516
(LRR_6) 		4 GLY A 245
SER A 251
VAL A 274
LEU A 242
 None
 0.93A 1yajB-2bnhA:
undetectable		 1yajB-2bnhA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cdu NADPH OXIDASE

(Lactobacillus
sanfranciscensis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLY A 341
SER A 339
VAL A 379
LEU A 346
 None
 1.33A 1yajB-2cduA:
undetectable		 1yajB-2cduA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cya TYROSYL-TRNA
SYNTHETASE

(Aeropyrum
pernix) 		PF00579
(tRNA-synt_1b) 		4 GLY A  28
SER A  32
VAL A   6
LEU A  26
 None
 1.30A 1yajB-2cyaA:
2.0		 1yajB-2cyaA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dm9 V-TYPE ATP SYNTHASE
SUBUNIT E

(Pyrococcus
horikoshii) 		PF01991
(vATP-synt_E) 		4 GLY A 160
SER A 126
VAL A 106
LEU A  94
 None
 1.28A 1yajB-2dm9A:
undetectable		 1yajB-2dm9A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fu0 CYCLOPHILIN,
PUTATIVE

(Plasmodium
falciparum) 		PF00160
(Pro_isomerase) 		4 GLY A 124
SER A  20
VAL A  30
LEU A  84
 None
 0.96A 1yajB-2fu0A:
undetectable		 1yajB-2fu0A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjs USG-1 PROTEIN
HOMOLOG

(Pseudomonas
aeruginosa) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 GLY A 243
SER A 159
VAL A 316
LEU A 287
 None
 1.22A 1yajB-2hjsA:
undetectable		 1yajB-2hjsA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i50 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 16

(Homo sapiens) 		PF02148
(zf-UBP) 		4 GLY A  66
SER A  53
VAL A  89
LEU A  75
 None
 1.33A 1yajB-2i50A:
undetectable		 1yajB-2i50A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6x HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Porphyromonas
gingivalis) 		PF13419
(HAD_2) 		4 GLY A  10
SER A 108
VAL A 114
LEU A  16
 None
 1.15A 1yajB-2i6xA:
undetectable		 1yajB-2i6xA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iu4 DIHYDROXYACETONE
KINASE

(Lactococcus
lactis) 		PF02733
(Dak1) 		4 GLY A 186
SER A 135
VAL A 148
LEU A 260
 None
 1.19A 1yajB-2iu4A:
2.4		 1yajB-2iu4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbr P-HYDROXYPHENYLACETA
TE HYDROXYLASE C2
OXYGENASE COMPONENT

(Acinetobacter
baumannii) 		PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 GLY A 172
SER A 220
VAL A  64
LEU A 117
 None
 1.35A 1yajB-2jbrA:
undetectable		 1yajB-2jbrA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jg2 SERINE
PALMITOYLTRANSFERASE

(Sphingomonas
paucimobilis) 		PF00155
(Aminotran_1_2) 		4 GLY A 203
SER A 235
VAL A 259
LEU A 214
 None
 1.05A 1yajB-2jg2A:
undetectable		 1yajB-2jg2A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjx URIDYLATE KINASE

(Bacillus
anthracis) 		PF00696
(AA_kinase) 		4 GLY A  88
SER A  92
VAL A  98
LEU A  86
 None
 1.15A 1yajB-2jjxA:
undetectable		 1yajB-2jjxA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqo NEUROPILIN-2

(Homo sapiens) 		PF00431
(CUB)
PF00754
(F5_F8_type_C) 		4 GLY A 218
SER A 246
VAL A 222
LEU A 444
 None
 1.12A 1yajB-2qqoA:
undetectable		 1yajB-2qqoA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qtp UNCHARACTERIZED
PROTEIN

(Ruegeria
pomeroyi) 		PF06684
(AA_synth) 		4 GLY A  80
SER A  82
VAL A  30
LEU A 134
 None
 1.20A 1yajB-2qtpA:
undetectable		 1yajB-2qtpA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rjo TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Paraburkholderia
phytofirmans) 		PF13407
(Peripla_BP_4) 		4 GLY A 295
SER A 297
VAL A 146
LEU A 149
 None
 1.14A 1yajB-2rjoA:
3.5		 1yajB-2rjoA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w58 PRIMOSOME COMPONENT
(HELICASE LOADER)

(Geobacillus
kaustophilus) 		PF01695
(IstB_IS21) 		4 GLY A 232
SER A 263
VAL A 197
LEU A 274
 None
 1.07A 1yajB-2w58A:
undetectable		 1yajB-2w58A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wek ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLY A 100
SER A 128
VAL A 135
LEU A 154
 None
 1.35A 1yajB-2wekA:
undetectable		 1yajB-2wekA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x66 PRNB

(Pseudomonas
fluorescens) 		PF08933
(DUF1864) 		4 GLY A 295
SER A 175
VAL A 354
LEU A 166
 None
 1.18A 1yajB-2x66A:
undetectable		 1yajB-2x66A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzm D-ALANINE--D-ALANINE
LIGASE

(Thermus
thermophilus) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 GLY A 288
SER A 293
VAL A  16
LEU A  80
 None
 1.30A 1yajB-2yzmA:
undetectable		 1yajB-2yzmA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zux YESW PROTEIN

(Bacillus
subtilis) 		no annotation 4 GLY A  98
SER A 102
VAL A  60
LEU A  83
 None
 1.26A 1yajB-2zuxA:
undetectable		 1yajB-2zuxA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwi ALPHA-/BETA-GALACTOS
IDE
ALPHA-2,3-SIALYLTRAN
SFERASE

(Photobacterium
phosphoreum) 		PF11477
(PM0188) 		4 GLY A 149
SER A 360
VAL A 154
LEU A 120
 GOL  A   5 (-3.4A)
C5P  A   1 ( 2.6A)
None
None
 1.13A 1yajB-2zwiA:
2.2		 1yajB-2zwiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6m SPERMINE SYNTHASE

(Homo sapiens) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 GLY A  25
SER A  28
VAL A  93
LEU A 100
 None
 1.33A 1yajB-3c6mA:
undetectable		 1yajB-3c6mA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3

(Homo sapiens) 		PF03853
(YjeF_N)
PF09532
(FDF) 		4 GLY A 354
SER A 313
VAL A 362
LEU A 339
 None
 1.36A 1yajB-3d3jA:
undetectable		 1yajB-3d3jA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE

(Staphylococcus
epidermidis) 		PF01715
(IPPT) 		4 GLY A 248
SER A 273
VAL A 266
LEU A 226
 None
 1.07A 1yajB-3d3qA:
undetectable		 1yajB-3d3qA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE

(Bifidobacterium
adolescentis) 		PF02811
(PHP) 		4 GLY A 271
SER A 259
VAL A  44
LEU A  39
 None
 1.10A 1yajB-3e0fA:
undetectable		 1yajB-3e0fA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epm THIAMINE
BIOSYNTHESIS PROTEIN
THIC

(Caulobacter
vibrioides) 		PF01964
(ThiC_Rad_SAM)
PF13667
(ThiC-associated) 		4 GLY A  60
SER A  63
VAL A 237
LEU A  75
 None
 1.28A 1yajB-3epmA:
undetectable		 1yajB-3epmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gri DIHYDROOROTASE

(Staphylococcus
aureus) 		PF01979
(Amidohydro_1) 		4 GLY A  75
SER A 326
VAL A 116
LEU A  61
 None
 1.22A 1yajB-3griA:
undetectable		 1yajB-3griA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Agrobacterium
fabrum) 		PF13377
(Peripla_BP_3) 		4 GLY A 255
SER A 252
VAL A 262
LEU A 287
 None
 1.27A 1yajB-3gv0A:
2.4		 1yajB-3gv0A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxj PYRROLO-QUINOLINE
QUINONE

(Methanococcus
maripaludis) 		PF01011
(PQQ)
PF13360
(PQQ_2)
PF13570
(PQQ_3) 		4 GLY A 271
SER A 258
VAL A 261
LEU A 277
 None
 1.18A 1yajB-3hxjA:
undetectable		 1yajB-3hxjA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ip1 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Thermotoga
maritima) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 GLY A 220
SER A 245
VAL A 260
LEU A 225
 None
 1.10A 1yajB-3ip1A:
undetectable		 1yajB-3ip1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iqd OCTOPINE
DEHYDROGENASE

(Pecten maximus) 		PF02317
(Octopine_DH) 		4 GLY B  19
SER B  23
VAL B  29
LEU B  17
 None
 1.25A 1yajB-3iqdB:
undetectable		 1yajB-3iqdB:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no5 UNCHARACTERIZED
PROTEIN

(Cupriavidus
pinatubonensis) 		PF05853
(BKACE) 		4 GLY A  95
SER A  59
VAL A  82
LEU A 129
 None
 1.20A 1yajB-3no5A:
undetectable		 1yajB-3no5A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npe 9-CIS-EPOXYCAROTENOI
D DIOXYGENASE 1,
CHLOROPLASTIC

(Zea mays) 		PF03055
(RPE65) 		4 GLY A 277
SER A 189
VAL A 152
LEU A 279
 None
 1.25A 1yajB-3npeA:
undetectable		 1yajB-3npeA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqq PUTATIVE LIPOPROTEIN

(Bacteroides
ovatus) 		PF16129
(DUF4841)
PF16130
(DUF4842) 		4 GLY A 294
SER A 297
VAL A 206
LEU A 292
 None
 1.14A 1yajB-3oqqA:
undetectable		 1yajB-3oqqA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oz2 DIGERANYLGERANYLGLYC
EROPHOSPHOLIPID
REDUCTASE

(Thermoplasma
acidophilum) 		PF01494
(FAD_binding_3) 		4 GLY A 164
SER A 161
VAL A   9
LEU A 278
 None
None
FAD  A 501 ( 4.8A)
None
 1.23A 1yajB-3oz2A:
undetectable		 1yajB-3oz2A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozx RNASE L INHIBITOR

(Sulfolobus
solfataricus) 		PF00005
(ABC_tran) 		4 GLY A 217
SER A 214
VAL A 169
LEU A 243
 None
 1.25A 1yajB-3ozxA:
undetectable		 1yajB-3ozxA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9p ACKA

(Mycobacterium
avium) 		PF00871
(Acetate_kinase) 		4 GLY A 339
SER A 362
VAL A 332
LEU A 305
 None
 1.10A 1yajB-3r9pA:
undetectable		 1yajB-3r9pA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6f HYPOTHETICAL
ACETYLTRANSFERASE

(Deinococcus
radiodurans) 		PF13673
(Acetyltransf_10) 		4 GLY A  88
SER A  91
VAL A  80
LEU A   6
 GLY  A  88 (-0.0A)
SER  A  91 (-0.0A)
VAL  A  80 (-0.6A)
LEU  A   6 ( 0.5A)
 1.29A 1yajB-3s6fA:
undetectable		 1yajB-3s6fA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3snh DYNAMIN-1

(Homo sapiens) 		PF00169
(PH)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED) 		4 GLY A 202
SER A 175
VAL A 219
LEU A 227
 None
 0.96A 1yajB-3snhA:
undetectable		 1yajB-3snhA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqi GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]

(Coxiella
burnetii) 		PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		4 GLY A 236
SER A 240
VAL A 273
LEU A 265
 None
 1.33A 1yajB-3tqiA:
2.5		 1yajB-3tqiA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0f BETA-KETOACYL
SYNTHASE

(Brucella
abortus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLY A  50
SER A  34
VAL A 228
LEU A 191
 None
None
None
MOH  A 412 ( 4.0A)
 1.26A 1yajB-3u0fA:
undetectable		 1yajB-3u0fA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vx4 PUTATIVE ABC
TRANSPORTER,
ATP-BINDING PROTEIN
COMA

(Streptococcus
mutans) 		PF00005
(ABC_tran) 		4 GLY A 561
SER A 565
VAL A 740
LEU A 758
 None
ATP  A 801 (-3.5A)
None
None
 0.99A 1yajB-3vx4A:
undetectable		 1yajB-3vx4A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bf7 ARABINOGALACTAN
ENDO-1,4-BETA-GALACT
OSIDASE A

(Aspergillus
nidulans) 		PF07745
(Glyco_hydro_53) 		4 GLY A 299
SER A  11
VAL A  20
LEU A 314
 None
 1.20A 1yajB-4bf7A:
undetectable		 1yajB-4bf7A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dcc PUTATIVE HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13419
(HAD_2) 		4 GLY A  14
SER A 112
VAL A 122
LEU A  20
 CL  A 301 ( 3.6A)
CL  A 301 (-2.8A)
None
None
 0.98A 1yajB-4dccA:
undetectable		 1yajB-4dccA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dg5 PHOSPHOGLYCERATE
KINASE

(Staphylococcus
aureus) 		PF00162
(PGK) 		4 GLY A 352
SER A 355
VAL A 316
LEU A 379
 None
 1.36A 1yajB-4dg5A:
undetectable		 1yajB-4dg5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4frz KINESIN-LIKE
CALMODULIN-BINDING
PROTEIN

(Arabidopsis
thaliana) 		PF00225
(Kinesin) 		4 GLY A1119
SER A1087
VAL A1123
LEU A1143
 None
EDO  A1306 ( 4.0A)
None
None
 1.27A 1yajB-4frzA:
undetectable		 1yajB-4frzA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwi ABC-TYPE
DIPEPTIDE/OLIGOPEPTI
DE/NICKEL TRANSPORT
SYSTEM, ATPASE
COMPONENT

(Caldanaerobacter
subterraneus) 		PF00005
(ABC_tran)
PF08352
(oligo_HPY) 		4 GLY B  41
SER B  45
VAL B 234
LEU B 254
 None
ATP  B 402 (-3.7A)
None
None
 0.89A 1yajB-4fwiB:
2.5		 1yajB-4fwiB:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idt MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 14

(Homo sapiens) 		PF00069
(Pkinase) 		4 GLY A 514
SER A 581
VAL A 567
LEU A 512
 None
 1.21A 1yajB-4idtA:
undetectable		 1yajB-4idtA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED

(Xanthomonas
oryzae) 		PF01053
(Cys_Met_Meta_PP) 		4 GLY B 292
SER B 295
VAL B 313
LEU B 273
 None
 1.30A 1yajB-4iyoB:
undetectable		 1yajB-4iyoB:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lcm TRANSESTERASE

(Aspergillus
terreus) 		PF00144
(Beta-lactamase) 		4 GLY A 277
SER A 274
VAL A 282
LEU A 382
 None
 1.34A 1yajB-4lcmA:
undetectable		 1yajB-4lcmA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okd ISOAMYLASE

(Chlamydomonas
reinhardtii) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 GLY A 678
SER A 683
VAL A 788
LEU A 734
 None
 1.36A 1yajB-4okdA:
1.1		 1yajB-4okdA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4o DNA POLYMERASE BETA

(Leishmania
infantum) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		4 GLY A 341
SER A 279
VAL A 212
LEU A 240
 None
 1.26A 1yajB-4p4oA:
undetectable		 1yajB-4p4oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4peq RIBONUCLEASE/ANGIOGE
NIN INHIBITOR 1

(Bos taurus) 		PF13516
(LRR_6) 		4 GLY B 245
SER B 251
VAL B 274
LEU B 242
 None
 0.89A 1yajB-4peqB:
undetectable		 1yajB-4peqB:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4phs PUTATIVE
GLYCOSYLTRANSFERASE
(GALT1)

(Streptococcus
parasanguinis) 		PF08759
(GT-D) 		4 GLY A 110
SER A  63
VAL A  27
LEU A  71
 None
 1.36A 1yajB-4phsA:
undetectable		 1yajB-4phsA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4a UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288

(Thermotoga
maritima) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 GLY B 388
SER B 392
VAL B 568
LEU B 586
 None
 1.05A 1yajB-4q4aB:
undetectable		 1yajB-4q4aB:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288

(Thermotoga
maritima) 		PF00005
(ABC_tran) 		4 GLY A 388
SER A 392
VAL A 568
LEU A 586
 None
 1.03A 1yajB-4q7lA:
undetectable		 1yajB-4q7lA:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qww ACETYLCHOLINESTERASE

(Bungarus
fasciatus) 		PF00135
(COesterase) 		4 GLY A 437
SER A 329
VAL A 324
LEU A 430
 None
 0.88A 1yajB-4qwwA:
48.2		 1yajB-4qwwA:
35.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r20 CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2

(Danio rerio) 		PF00067
(p450) 		4 GLY A 382
SER A 380
VAL A  92
LEU A  70
 None
 1.28A 1yajB-4r20A:
undetectable		 1yajB-4r20A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uvq THIAZOLINE
OXIDASE/SUBTILISIN-L
IKE PROTEASE

(Prochloron sp.) 		no annotation 4 GLY A1047
SER A1019
VAL A1042
LEU A1172
 None
 1.32A 1yajB-4uvqA:
undetectable		 1yajB-4uvqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x4j PUTATIVE OXYGENASE

(Amycolatopsis
orientalis) 		PF01494
(FAD_binding_3) 		4 GLY A 150
SER A 156
VAL A 162
LEU A 148
 None
 1.35A 1yajB-4x4jA:
undetectable		 1yajB-4x4jA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x7m TARM

(Staphylococcus
aureus) 		PF00534
(Glycos_transf_1) 		4 GLY A 356
SER A 325
VAL A 360
LEU A 379
 UDP  A 500 (-3.2A)
None
None
None
 1.35A 1yajB-4x7mA:
3.7		 1yajB-4x7mA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0n PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Streptobacillus
moniliformis) 		PF13407
(Peripla_BP_4) 		4 GLY A 242
SER A 246
VAL A 256
LEU A 171
 None
 1.15A 1yajB-4z0nA:
3.7		 1yajB-4z0nA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5adv ENTEROCHELIN UPTAKE
PERIPLASMIC BINDING
PROTEIN

(Campylobacter
jejuni) 		PF01497
(Peripla_BP_2) 		4 GLY A  59
SER A 297
VAL A 150
LEU A 137
 None
 1.20A 1yajB-5advA:
undetectable		 1yajB-5advA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq2 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Pseudomonas
aeruginosa) 		PF00275
(EPSP_synthase) 		4 GLY A 168
SER A 165
VAL A 194
LEU A  97
 None
EPU  A 501 (-2.8A)
None
None
 1.24A 1yajB-5bq2A:
undetectable		 1yajB-5bq2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d3q DYNAMIN-1,DYNAMIN-1

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 GLY A 202
SER A 175
VAL A 219
LEU A 227
 None
 0.92A 1yajB-5d3qA:
undetectable		 1yajB-5d3qA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsm EXO-BETA-D-GLUCOSAMI
NIDASE

(Thermococcus
kodakarensis) 		PF02449
(Glyco_hydro_42) 		4 GLY A 704
SER A 366
VAL A 672
LEU A 740
 None
 1.31A 1yajB-5gsmA:
undetectable		 1yajB-5gsmA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2g DIAMINOPIMELATE
EPIMERASE

(Corynebacterium
glutamicum) 		PF01678
(DAP_epimerase) 		4 GLY A 222
SER A 220
VAL A 245
LEU A 263
 None
 1.25A 1yajB-5h2gA:
undetectable		 1yajB-5h2gA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy7 PUTATIVE PRE-MRNA
SPLICING PROTEIN

(Chaetomium
thermophilum) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 GLY A 999
SER A 982
VAL A1008
LEU A 989
 None
 1.25A 1yajB-5hy7A:
undetectable		 1yajB-5hy7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 GLY B 467
SER B 475
VAL B 479
LEU B 416
 None
 1.30A 1yajB-5ip9B:
undetectable		 1yajB-5ip9B:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kte DIVALENT METAL
CATION TRANSPORTER
MNTH

(Deinococcus
radiodurans) 		PF01566
(Nramp) 		4 GLY A 324
SER A 328
VAL A 179
LEU A 321
 None
 1.18A 1yajB-5kteA:
undetectable		 1yajB-5kteA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC

(Oryza sativa) 		PF01593
(Amino_oxidase) 		4 GLY A 525
SER A 521
VAL A 370
LEU A 562
 None
 1.32A 1yajB-5mogA:
undetectable		 1yajB-5mogA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr HETERODISULFIDE
REDUCTASE, SUBUNIT A

(Methanothermococcus
thermolithotrophicus) 		PF07992
(Pyr_redox_2)
PF13187
(Fer4_9) 		4 GLY A 179
SER A 177
VAL A 206
LEU A 199
 None
 1.22A 1yajB-5odrA:
undetectable		 1yajB-5odrA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w94 MAU2 CHROMATID
COHESION FACTOR
HOMOLOG

(Saccharomyces
cerevisiae) 		PF10345
(Cohesin_load) 		4 GLY A 164
SER A 180
VAL A 142
LEU A 135
 None
 1.27A 1yajB-5w94A:
undetectable		 1yajB-5w94A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Komagataella
phaffii) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 GLY B 460
SER B 468
VAL B 472
LEU B 409
 None
 1.32A 1yajB-5xogB:
undetectable		 1yajB-5xogB:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bja ACETYL-COA
ACETYLTRANSFERASE A

(Ascaris suum) 		no annotation 4 GLY A 256
SER A 119
VAL A  36
LEU A  25
 None
 1.36A 1yajB-6bjaA:
undetectable		 1yajB-6bjaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c7v -

(-) 		no annotation 4 GLY A  36
SER A  40
VAL A  69
LEU A  10
 None
 1.27A 1yajB-6c7vA:
undetectable		 1yajB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c80 CYTOKININ OXIDASE
LUCKX1.1

(Linum
usitatissimum) 		no annotation 4 GLY A 229
SER A 179
VAL A 202
LEU A 516
 FAD  A 601 ( 3.7A)
FAD  A 601 (-3.4A)
None
None
 1.37A 1yajB-6c80A:
undetectable		 1yajB-6c80A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cn1 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Pseudomonas
putida) 		no annotation 4 GLY A 168
SER A 165
VAL A 194
LEU A  97
 None
EPU  A 501 (-2.5A)
None
None
 1.25A 1yajB-6cn1A:
undetectable		 1yajB-6cn1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e9p -

(-) 		no annotation 4 GLY A 129
SER A  97
VAL A  58
LEU A 124
 None
 1.13A 1yajB-6e9pA:
undetectable		 1yajB-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fpe TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN TSAB
TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE

(Thermotoga
maritima;
Thermotoga
maritima) 		no annotation
no annotation 		4 GLY A  79
SER B  99
VAL B  74
LEU B  59
 None
 1.00A 1yajB-6fpeA:
undetectable		 1yajB-6fpeA:
undetectable