SIMILAR PATTERNS OF AMINO ACIDS FOR 1YA4_C_CTXC3_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4o DNA NUCLEOTIDE
EXCISION REPAIR
ENZYME UVRB

(Thermus
thermophilus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF12344
(UvrB) 		4 LEU A  25
PRO A 325
ILE A  50
LEU A  53
 None
 1.02A 1ya4C-1c4oA:
undetectable		 1ya4C-1c4oA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dll TETANUS TOXIN

(Clostridium
tetani) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 LEU A 889
PRO A 910
ILE A 934
LEU A1072
 None
 1.02A 1ya4C-1dllA:
undetectable		 1ya4C-1dllA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h74 HOMOSERINE KINASE

(Methanocaldococcus
jannaschii) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 LEU A 170
PRO A  32
ILE A 266
LEU A  27
 None
 1.06A 1ya4C-1h74A:
undetectable		 1ya4C-1h74A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ije ELONGATION FACTOR
1-BETA

(Saccharomyces
cerevisiae) 		PF00736
(EF1_GNE) 		4 LEU B1184
PRO B1129
ILE B1170
LEU B1125
 None
 0.96A 1ya4C-1ijeB:
undetectable		 1ya4C-1ijeB:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5s PENICILLIN G ACYLASE
BETA SUBUNIT

(Escherichia
coli) 		PF01804
(Penicil_amidase) 		4 LEU B 296
PRO B 448
ILE B 346
LEU B 347
 None
 1.17A 1ya4C-1k5sB:
0.2		 1ya4C-1k5sB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kdx CBP

(Mus musculus) 		PF02172
(KIX) 		4 LEU A 603
PRO A 613
ILE A 657
LEU A 607
 None
 1.14A 1ya4C-1kdxA:
3.6		 1ya4C-1kdxA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1poy SPERMIDINE/PUTRESCIN
E-BINDING PROTEIN

(Escherichia
coli) 		PF13416
(SBP_bac_8) 		4 LEU 1  29
PRO 1  82
ILE 1 275
LEU 1 274
 None
 1.15A 1ya4C-1poy1:
0.9		 1ya4C-1poy1:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q20 SULFOTRANSFERASE
FAMILY, CYTOSOLIC,
2B, MEMBER 1 ISOFORM
B

(Homo sapiens) 		PF00685
(Sulfotransfer_1) 		4 LEU A 121
PRO A  89
ILE A  83
LEU A  84
 None
 1.01A 1ya4C-1q20A:
0.2		 1ya4C-1q20A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6j LANOSTEROL SYNTHASE

(Homo sapiens) 		PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N) 		4 LEU A 131
PRO A 168
ILE A 163
LEU A 164
 None
 1.08A 1ya4C-1w6jA:
0.0		 1ya4C-1w6jA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y56 SARCOSINE OXIDASE

(Pyrococcus
horikoshii) 		PF01266
(DAO) 		4 LEU B  91
PRO B 113
ILE B 117
LEU B 116
 None
 1.10A 1ya4C-1y56B:
0.7		 1ya4C-1y56B:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abj BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE,
CYTOSOLIC

(Homo sapiens) 		PF01063
(Aminotran_4) 		4 LEU A 261
PRO A 206
ILE A 341
LEU A 202
 None
 1.10A 1ya4C-2abjA:
undetectable		 1ya4C-2abjA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d86 VAV-3 PROTEIN

(Homo sapiens) 		PF11971
(CAMSAP_CH) 		4 LEU A  18
PRO A 137
ILE A 116
LEU A 119
 None
 1.04A 1ya4C-2d86A:
undetectable		 1ya4C-2d86A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmt METHIONYL-TRNA FMET
FORMYLTRANSFERASE

(Escherichia
coli) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 LEU A 286
PRO A 234
ILE A 214
LEU A 238
 None
 1.12A 1ya4C-2fmtA:
undetectable		 1ya4C-2fmtA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2him L-ASPARAGINASE 1

(Escherichia
coli) 		PF00710
(Asparaginase) 		4 LEU A  35
PRO A  26
ILE A  15
LEU A 121
 None
 0.98A 1ya4C-2himA:
undetectable		 1ya4C-2himA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hqm GLUTATHIONE
REDUCTASE

(Saccharomyces
cerevisiae) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 438
PRO A 380
ILE A 448
LEU A 449
 None
 1.15A 1ya4C-2hqmA:
undetectable		 1ya4C-2hqmA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6x HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Porphyromonas
gingivalis) 		PF13419
(HAD_2) 		4 LEU A 106
PRO A 125
ILE A  14
LEU A  13
 None
 1.03A 1ya4C-2i6xA:
undetectable		 1ya4C-2i6xA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jkm FOCAL ADHESION
KINASE 1

(Gallus gallus) 		PF07714
(Pkinase_Tyr) 		4 LEU A 651
PRO A 622
ILE A 615
LEU A 616
 None
 1.14A 1ya4C-2jkmA:
undetectable		 1ya4C-2jkmA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l25 UNCHARACTERIZED
PROTEIN

(Bordetella
bronchiseptica) 		PF13554
(DUF4128) 		4 LEU A  15
PRO A 113
ILE A 130
LEU A  91
 None
 1.16A 1ya4C-2l25A:
undetectable		 1ya4C-2l25A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og2 PUTATIVE SIGNAL
RECOGNITION PARTICLE
RECEPTOR

(Arabidopsis
thaliana) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 LEU A 150
PRO A 246
ILE A 131
LEU A 214
 None
 1.17A 1ya4C-2og2A:
2.1		 1ya4C-2og2A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2orz NEUROPILIN-1

(Rattus
norvegicus) 		PF00754
(F5_F8_type_C) 		4 LEU A 464
PRO A 398
ILE A 426
LEU A 333
 None
 1.12A 1ya4C-2orzA:
undetectable		 1ya4C-2orzA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbf PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE
BETA-ASPARTATE
METHYLTRANSFERASE

(Plasmodium
falciparum) 		PF01135
(PCMT) 		4 LEU A  94
PRO A  80
ILE A  75
LEU A  74
 SAH  A 301 ( 4.9A)
None
None
None
 1.16A 1ya4C-2pbfA:
undetectable		 1ya4C-2pbfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q50 GLYOXYLATE
REDUCTASE/HYDROXYPYR
UVATE REDUCTASE

(Homo sapiens) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A 254
PRO A 127
ILE A 241
LEU A 268
 None
 1.11A 1ya4C-2q50A:
undetectable		 1ya4C-2q50A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjw UNCHARACTERIZED
PROTEIN XCC1541

(Xanthomonas
campestris) 		no annotation 4 LEU A  77
PRO A  16
ILE A  65
LEU A  62
 None
 1.09A 1ya4C-2qjwA:
10.0		 1ya4C-2qjwA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wa5 FILAMIN-B

(Homo sapiens) 		PF00307
(CH) 		4 LEU A  53
PRO A 126
ILE A 118
LEU A 117
 None
 0.94A 1ya4C-2wa5A:
undetectable		 1ya4C-2wa5A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xik SERINE/THREONINE
PROTEIN KINASE 25

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 201
PRO A 242
ILE A 270
LEU A 264
 None
None
EDO  A1293 (-4.7A)
None
 1.07A 1ya4C-2xikA:
undetectable		 1ya4C-2xikA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv5 YJEQ PROTEIN

(Aquifex
aeolicus) 		PF03193
(RsgA_GTPase) 		4 LEU A 163
PRO A 224
ILE A 181
LEU A 185
 None
 0.87A 1ya4C-2yv5A:
undetectable		 1ya4C-2yv5A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiz DNA POLYMERASE
SLIDING CLAMP B

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A  19
PRO A  53
ILE A 241
LEU A 240
 None
 1.13A 1ya4C-3aizA:
undetectable		 1ya4C-3aizA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermotoga
maritima) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 LEU B 177
PRO B 162
ILE B 119
LEU B 106
 None
 1.03A 1ya4C-3al0B:
undetectable		 1ya4C-3al0B:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anp TRANSCRIPTIONAL
REPRESSOR, TETR
FAMILY

(Thermus
thermophilus) 		no annotation 4 LEU C  68
PRO C  82
ILE C 132
LEU C 131
 None
 1.16A 1ya4C-3anpC:
undetectable		 1ya4C-3anpC:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjq PHAGE-RELATED
PROTEIN

(Bordetella
bronchiseptica) 		PF03864
(Phage_cap_E) 		4 LEU A 131
PRO A 176
ILE A 307
LEU A 306
 None
 0.82A 1ya4C-3bjqA:
undetectable		 1ya4C-3bjqA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwk PENICILLIN-BINDING
PROTEIN 2

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF00912
(Transgly) 		4 LEU A 556
PRO A 674
ILE A 447
LEU A 451
 None
 1.09A 1ya4C-3dwkA:
undetectable		 1ya4C-3dwkA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9y ACETOLACTATE
SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A 175
PRO A 161
ILE A 192
LEU A 251
 None
 1.10A 1ya4C-3e9yA:
undetectable		 1ya4C-3e9yA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed4 ARYLSULFATASE

(Escherichia
coli) 		PF00884
(Sulfatase) 		4 LEU A 393
PRO A  43
ILE A 128
LEU A 131
 None
 0.97A 1ya4C-3ed4A:
undetectable		 1ya4C-3ed4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hcj PEPTIDE METHIONINE
SULFOXIDE REDUCTASE

(Xanthomonas
campestris) 		PF01641
(SelR) 		4 LEU A 131
PRO A  37
ILE A 100
LEU A 109
 None
 1.09A 1ya4C-3hcjA:
undetectable		 1ya4C-3hcjA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hoc FILAMIN-A

(Homo sapiens) 		PF00307
(CH) 		4 LEU A  80
PRO A 153
ILE A 145
LEU A 144
 None
 0.91A 1ya4C-3hocA:
undetectable		 1ya4C-3hocA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hz6 XYLULOKINASE

(Chromobacterium
violaceum) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 LEU A 196
PRO A 128
ILE A 134
LEU A 135
 None
 0.98A 1ya4C-3hz6A:
undetectable		 1ya4C-3hz6A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4s HISTIDINE TRIAD
PROTEIN

(Bradyrhizobium
japonicum) 		PF01230
(HIT) 		4 LEU A 105
PRO A 143
ILE A 116
LEU A 114
 None
 1.07A 1ya4C-3i4sA:
undetectable		 1ya4C-3i4sA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ilw DNA GYRASE SUBUNIT A

(Mycobacterium
tuberculosis) 		PF00521
(DNA_topoisoIV) 		4 LEU A 205
PRO A 167
ILE A 373
LEU A 370
 None
 0.84A 1ya4C-3ilwA:
undetectable		 1ya4C-3ilwA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksc LEGA CLASS

(Pisum sativum) 		PF00190
(Cupin_1) 		4 LEU A  15
PRO A  20
ILE A 382
LEU A 413
 None
 1.07A 1ya4C-3kscA:
undetectable		 1ya4C-3kscA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgx D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1

(Streptococcus
pyogenes) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A  21
PRO A 190
ILE A 229
LEU A 232
 None
 1.05A 1ya4C-3lgxA:
undetectable		 1ya4C-3lgxA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkt MULTI ANTIMICROBIAL
EXTRUSION PROTEIN
(NA(+)/DRUG
ANTIPORTER)
MATE-LIKE MDR EFFLUX
PUMP

(Vibrio cholerae) 		PF01554
(MatE) 		4 LEU A 101
PRO A 247
ILE A 239
LEU A 238
 None
 1.12A 1ya4C-3mktA:
undetectable		 1ya4C-3mktA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntx CYTOPLASMIC
L-ASPARAGINASE I

(Yersinia pestis) 		PF00710
(Asparaginase) 		4 LEU A  35
PRO A  26
ILE A  15
LEU A 121
 None
 0.99A 1ya4C-3ntxA:
undetectable		 1ya4C-3ntxA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqc UFM1-SPECIFIC
PROTEASE 2

(Mus musculus) 		PF07910
(Peptidase_C78) 		4 LEU A 260
PRO A 441
ILE A 416
LEU A 415
 None
 1.14A 1ya4C-3oqcA:
undetectable		 1ya4C-3oqcA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pw9 UPF0603 PROTEIN
AT1G54780,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF04536
(TPM_phosphatase) 		4 LEU A 194
PRO A 230
ILE A 226
LEU A 222
 None
 1.16A 1ya4C-3pw9A:
undetectable		 1ya4C-3pw9A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufi HYPOTHETICAL PROTEIN
BACOVA_04980

(Bacteroides
ovatus) 		PF13149
(Mfa_like_1) 		4 LEU A 232
PRO A 286
ILE A 249
LEU A 250
 None
 1.10A 1ya4C-3ufiA:
undetectable		 1ya4C-3ufiA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8b PUTATIVE
DEHYDROGENASE,
POSSIBLY
3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE

(Sinorhizobium
meliloti) 		PF13561
(adh_short_C2) 		4 LEU A  59
PRO A   6
ILE A  10
LEU A   9
 None
 1.15A 1ya4C-3v8bA:
4.4		 1ya4C-3v8bA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4acq ALPHA-2-MACROGLOBULI
N

(Homo sapiens) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 LEU A1046
PRO A1119
ILE A1068
LEU A1070
 None
 1.01A 1ya4C-4acqA:
undetectable		 1ya4C-4acqA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aio LIMIT DEXTRINASE

(Hordeum vulgare) 		PF02922
(CBM_48)
PF11852
(DUF3372) 		4 LEU A 361
PRO A 410
ILE A 420
LEU A 417
 None
 0.98A 1ya4C-4aioA:
undetectable		 1ya4C-4aioA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 LEU A 347
PRO A 264
ILE A 287
LEU A 286
 None
 1.15A 1ya4C-4av6A:
undetectable		 1ya4C-4av6A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7l FILAMIN-B

(Homo sapiens) 		PF00307
(CH)
PF00630
(Filamin) 		4 LEU A  53
PRO A 126
ILE A 118
LEU A 117
 None
 0.96A 1ya4C-4b7lA:
undetectable		 1ya4C-4b7lA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT

(Carboxydothermus
hydrogenoformans) 		PF03599
(CdhD)
PF04060
(FeS) 		4 LEU A 292
PRO A  91
ILE A 304
LEU A 303
 None
 1.07A 1ya4C-4c1nA:
undetectable		 1ya4C-4c1nA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dji PROBABLE
GLUTAMATE/GAMMA-AMIN
OBUTYRATE ANTIPORTER

(Escherichia
coli) 		PF13520
(AA_permease_2) 		4 LEU A 138
PRO A 127
ILE A 104
LEU A 107
 None
 1.15A 1ya4C-4djiA:
undetectable		 1ya4C-4djiA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eq5 DNA LIGASE

(Thermococcus
sibiricus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 LEU A 442
PRO A 526
ILE A 522
LEU A 534
 None
 1.01A 1ya4C-4eq5A:
undetectable		 1ya4C-4eq5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4faj PRGZ

(Enterococcus
faecalis) 		PF00496
(SBP_bac_5) 		4 LEU A 191
PRO A  75
ILE A 107
LEU A  94
 None
 1.08A 1ya4C-4fajA:
undetectable		 1ya4C-4fajA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gax AMORPHA-4,11-DIENE
SYNTHASE

(Artemisia annua) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 109
PRO A 503
ILE A  83
LEU A  87
 None
 1.10A 1ya4C-4gaxA:
2.5		 1ya4C-4gaxA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h8e UNDECAPRENYL
PYROPHOSPHATE
SYNTHASE

(Staphylococcus
aureus) 		PF01255
(Prenyltransf) 		4 LEU A 212
PRO A  25
ILE A  30
LEU A 199
 None
 1.12A 1ya4C-4h8eA:
undetectable		 1ya4C-4h8eA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jej GERANYLGERANYLGLYCER
YL PHOSPHATE
SYNTHASE

(Flavobacterium
johnsoniae) 		PF01884
(PcrB) 		4 LEU A 103
PRO A  87
ILE A 112
LEU A 111
 None
PGE  A 302 ( 3.2A)
None
None
 0.96A 1ya4C-4jejA:
undetectable		 1ya4C-4jejA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jwo PHOSPHATE BINDING
PROTEIN

(Planctopirus
limnophila) 		PF12727
(PBP_like) 		4 LEU A 160
PRO A 181
ILE A 145
LEU A 235
 None
 0.73A 1ya4C-4jwoA:
undetectable		 1ya4C-4jwoA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf7 NUP188

(Thermothelomyces
thermophila) 		PF10487
(Nup188) 		4 LEU A 588
PRO A 409
ILE A 554
LEU A 551
 None
 1.05A 1ya4C-4kf7A:
1.5		 1ya4C-4kf7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ljs PERIPLASMIC BINDING
PROTEIN

(Veillonella
parvula) 		PF01497
(Peripla_BP_2) 		4 LEU A  77
PRO A 311
ILE A 191
LEU A 190
 None
 1.17A 1ya4C-4ljsA:
undetectable		 1ya4C-4ljsA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mvt E3 SUMO-PROTEIN
LIGASE PIAS3

(Homo sapiens) 		PF02891
(zf-MIZ)
PF14324
(PINIT) 		4 LEU A 334
PRO A 297
ILE A 387
LEU A 388
 None
 1.16A 1ya4C-4mvtA:
undetectable		 1ya4C-4mvtA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nb5 DNA BINDING PROTEIN

(Mycobacterium
tuberculosis) 		no annotation 4 LEU A  41
PRO A  99
ILE A  77
LEU A  76
 None
 0.99A 1ya4C-4nb5A:
undetectable		 1ya4C-4nb5A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5a LACI FAMILY
TRANSCRIPTION
REGULATOR

(Bifidobacterium
animalis) 		PF13377
(Peripla_BP_3) 		4 LEU A  96
PRO A 166
ILE A 316
LEU A 313
 None
 0.94A 1ya4C-4o5aA:
2.4		 1ya4C-4o5aA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9f HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MCBR

(Escherichia
coli) 		PF00392
(GntR)
PF07729
(FCD) 		4 LEU A 215
PRO A  75
ILE A  85
LEU A  82
 None
 0.88A 1ya4C-4p9fA:
undetectable		 1ya4C-4p9fA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pel PENICILLIN G ACYLASE
SUBUNIT BETA

(Kluyvera
cryocrescens) 		PF01804
(Penicil_amidase) 		4 LEU B 296
PRO B 448
ILE B 346
LEU B 347
 None
 1.08A 1ya4C-4pelB:
undetectable		 1ya4C-4pelB:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pju COHESIN SUBUNIT SA-2
DOUBLE-STRAND-BREAK
REPAIR PROTEIN RAD21
HOMOLOG

(Homo sapiens) 		PF08514
(STAG)
no annotation 		4 LEU A 825
PRO B 376
ILE A 794
LEU A 795
 None
 0.96A 1ya4C-4pjuA:
undetectable		 1ya4C-4pjuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q73 PROLINE
DEHYDROGENASE

(Bradyrhizobium
diazoefficiens) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 LEU A 309
PRO A 229
ILE A 388
LEU A 336
 None
 1.16A 1ya4C-4q73A:
undetectable		 1ya4C-4q73A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s38 4-HYDROXY-3-METHYLBU
T-2-EN-1-YL
DIPHOSPHATE SYNTHASE

(Thermus
thermophilus) 		PF04551
(GcpE) 		4 LEU A 393
PRO A 348
ILE A 380
LEU A 381
 None
 0.97A 1ya4C-4s38A:
undetectable		 1ya4C-4s38A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u60 STRUCTURAL PROTEIN
VP1

(Human
polyomavirus 8) 		PF00718
(Polyoma_coat) 		4 LEU A 296
PRO A 162
ILE A  96
LEU A  98
 None
 1.14A 1ya4C-4u60A:
undetectable		 1ya4C-4u60A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w4t MXAA

(Stigmatella
aurantiaca) 		PF07993
(NAD_binding_4) 		4 LEU A1232
PRO A1143
ILE A1239
LEU A1269
 None
 1.17A 1ya4C-4w4tA:
0.8		 1ya4C-4w4tA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd2 AROMATIC-AMINO-ACID
TRANSAMINASE TYRB

(Burkholderia
cenocepacia) 		PF00155
(Aminotran_1_2) 		4 LEU A 380
PRO A 184
ILE A 369
LEU A  31
 None
 0.99A 1ya4C-4wd2A:
undetectable		 1ya4C-4wd2A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wyr ACETYL-COA
ACETYLTRANSFERASE

(Clostridium
acetobutylicum) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 LEU A 358
PRO A 271
ILE A 258
LEU A 256
 None
 0.93A 1ya4C-4wyrA:
undetectable		 1ya4C-4wyrA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xeu TRANSKETOLASE

(Pseudomonas
aeruginosa) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A  40
PRO A  52
ILE A  71
LEU A  74
 None
EDO  A 701 (-4.8A)
None
None
 1.07A 1ya4C-4xeuA:
undetectable		 1ya4C-4xeuA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y85 MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE 8

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 193
PRO A 116
ILE A 108
LEU A 110
 None
 1.15A 1ya4C-4y85A:
undetectable		 1ya4C-4y85A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgz ANTIZYME INHIBITOR 1

(Homo sapiens) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 LEU A 212
PRO A 272
ILE A 268
LEU A 232
 None
 1.00A 1ya4C-4zgzA:
undetectable		 1ya4C-4zgzA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ax0 RHODOPSIN I

(Acetabularia
acetabulum) 		PF01036
(Bac_rhodopsin) 		4 LEU A  98
PRO A 189
ILE A 182
LEU A 181
 None
RET  A 301 (-4.1A)
None
None
 1.06A 1ya4C-5ax0A:
undetectable		 1ya4C-5ax0A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bqn BOTULINUM NEUROTOXIN
TYPE D,BOTULINUM
NEUROTOXIN TYPE D

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		4 LEU A 424
PRO A  61
ILE A 165
LEU A 166
 None
 1.14A 1ya4C-5bqnA:
undetectable		 1ya4C-5bqnA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f38 ACETYL-COA
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 LEU B 359
PRO B 272
ILE B 259
LEU B 257
 None
 0.92A 1ya4C-5f38B:
undetectable		 1ya4C-5f38B:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9s SERINE--PYRUVATE
AMINOTRANSFERASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		4 LEU A 219
PRO A  34
ILE A 279
LEU A 276
 None
 1.14A 1ya4C-5f9sA:
undetectable		 1ya4C-5f9sA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fv0 ESSC

(Geobacillus
thermodenitrificans) 		PF01580
(FtsK_SpoIIIE) 		4 LEU A1319
PRO A1476
ILE A1297
LEU A1298
 None
 1.12A 1ya4C-5fv0A:
undetectable		 1ya4C-5fv0A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h65 PROTECTION OF
TELOMERES PROTEIN 1

(Homo sapiens) 		no annotation 4 LEU A 483
PRO A 491
ILE A 455
LEU A 454
 None
 1.11A 1ya4C-5h65A:
undetectable		 1ya4C-5h65A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idb NATTERIN-3

(Crassostrea
gigas) 		no annotation 4 LEU B  48
PRO B  41
ILE B 111
LEU B  28
 BMA  B1001 ( 4.9A)
None
None
None
 1.08A 1ya4C-5idbB:
undetectable		 1ya4C-5idbB:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lq4 CYAGOX

(Cyanothece sp.
PCC 7425) 		PF00881
(Nitroreductase) 		4 LEU A 191
PRO A  92
ILE A 145
LEU A 143
 None
 1.07A 1ya4C-5lq4A:
undetectable		 1ya4C-5lq4A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m3c DIGUANYLATE CYCLASE

(Pseudomonas
aeruginosa) 		no annotation 4 LEU A1080
PRO A1100
ILE A1086
LEU A1085
 None
 1.07A 1ya4C-5m3cA:
undetectable		 1ya4C-5m3cA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mji BRAMP DOMAIN PROTEIN

(Streptomyces
davaonensis) 		PF03358
(FMN_red) 		4 LEU A 149
PRO A  90
ILE A 103
LEU A 104
 None
7O6  A 301 (-4.2A)
None
None
 1.14A 1ya4C-5mjiA:
undetectable		 1ya4C-5mjiA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz6 SEPARASE

(Caenorhabditis
elegans) 		PF03568
(Peptidase_C50) 		4 LEU 1 806
PRO 1 587
ILE 1 732
LEU 1 748
 None
 1.17A 1ya4C-5mz61:
undetectable		 1ya4C-5mz61:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN

(Chaetomium
thermophilum) 		PF06427
(UDP-g_GGTase) 		4 LEU A 373
PRO A 883
ILE A 361
LEU A 360
 None
 1.17A 1ya4C-5mzoA:
undetectable		 1ya4C-5mzoA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n0c TETANUS TOXIN

(Clostridium
tetani) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 LEU A 889
PRO A 910
ILE A 934
LEU A1072
 None
 1.06A 1ya4C-5n0cA:
undetectable		 1ya4C-5n0cA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nno ALDEHYDE
DEHYDROGENASE

(Trypanosoma
brucei) 		PF00171
(Aldedh) 		4 LEU A  49
PRO A   9
ILE A 134
LEU A 131
 None
 1.09A 1ya4C-5nnoA:
undetectable		 1ya4C-5nnoA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0x PUTATIVE FERRIC
REDUCTASE

(Cylindrospermum
stagnale) 		PF08022
(FAD_binding_8)
PF08030
(NAD_binding_6) 		4 LEU A 533
PRO A 467
ILE A 550
LEU A 547
 None
 1.03A 1ya4C-5o0xA:
undetectable		 1ya4C-5o0xA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uoh CARBOXYLESTERASE A

(Mycobacterium
tuberculosis) 		PF00561
(Abhydrolase_1) 		4 LEU A 217
PRO A 108
ILE A  92
LEU A  91
 None
 1.04A 1ya4C-5uohA:
13.9		 1ya4C-5uohA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w75 ELONGATION FACTOR TU

(Thermotoga
neapolitana) 		no annotation 4 LEU A 157
PRO A 129
ILE A  18
LEU A 104
 None
 1.10A 1ya4C-5w75A:
undetectable		 1ya4C-5w75A:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x03 HTH-TYPE
TRANSCRIPTIONAL
REGULATORY PROTEIN
GABR

(Bacillus
subtilis) 		PF00155
(Aminotran_1_2) 		4 LEU A 415
PRO A 203
ILE A 446
LEU A 445
 None
 1.10A 1ya4C-5x03A:
undetectable		 1ya4C-5x03A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt0 ARCHAEAL RIBOSOMAL
STALK PROTEIN AP1
PROBABLE TRANSLATION
INITIATION FACTOR
IF-2

(Aeropyrum
pernix) 		no annotation 4 LEU A 226
PRO A 207
ILE A 196
LEU B 105
 None
 1.13A 1ya4C-5yt0A:
undetectable		 1ya4C-5yt0A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN

(Human
immunodeficiency
virus 1;
Influenza A
virus) 		no annotation 4 LEU A  70
PRO A  58
ILE A 267
LEU A 112
 None
 1.17A 1ya4C-6a0zA:
undetectable		 1ya4C-6a0zA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bcq TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY M
MEMBER 4

(Mus musculus) 		no annotation 4 LEU B 510
PRO B 501
ILE B 474
LEU B 477
 None
 0.99A 1ya4C-6bcqB:
undetectable		 1ya4C-6bcqB:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bwc POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
CAPD

(Bacillus
thuringiensis) 		no annotation 4 LEU A  60
PRO A  30
ILE A  10
LEU A   9
 None
 1.18A 1ya4C-6bwcA:
1.5		 1ya4C-6bwcA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
PROTEIN, CAS5E
FAMILY

(Thermobifida
fusca) 		no annotation 4 LEU M 162
PRO M  66
ILE M 185
LEU M 184
 None
 1.13A 1ya4C-6c66M:
undetectable		 1ya4C-6c66M:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN

(Homo sapiens) 		no annotation 4 LEU A 508
PRO A 482
ILE A 550
LEU A 486
 None
 1.01A 1ya4C-6ei1A:
undetectable		 1ya4C-6ei1A:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3

(Homo sapiens) 		no annotation 4 LEU A 401
PRO A  45
ILE A  30
LEU A  41
 None
 1.10A 1ya4C-6en4A:
undetectable		 1ya4C-6en4A:
10.44