SIMILAR PATTERNS OF AMINO ACIDS FOR 1YA4_A_CTXA11_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a5i | PLASMINOGENACTIVATOR (Desmodusrotundus) |
PF00089(Trypsin) | 4 | MET A 202LEU A 210GLY A 211LEU A 162 | None | 0.90A | 1ya4A-1a5iA:undetectable | 1ya4A-1a5iA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ev1 | ECHOVIRUS 1 (Enterovirus B) |
PF00073(Rhv) | 4 | PRO 2 56LEU 2 91GLY 2 90PRO 2 247 | None | 0.93A | 1ya4A-1ev12:undetectable | 1ya4A-1ev12:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1u | TYROSYL-TRNASYNTHETASE (Methanocaldococcusjannaschii) |
PF00579(tRNA-synt_1b) | 4 | LEU A 69GLY A 105LEU A 79PRO A 37 | None | 0.77A | 1ya4A-1j1uA:undetectable | 1ya4A-1j1uA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m0w | GLUTATHIONESYNTHETASE (Saccharomycescerevisiae) |
PF03199(GSH_synthase)PF03917(GSH_synth_ATP) | 4 | LEU A 336GLY A 337LYS A 346LEU A 350 | None | 0.88A | 1ya4A-1m0wA:undetectable | 1ya4A-1m0wA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqt | POLYPROTEIN CAPSIDPROTEIN (Enterovirus B) |
PF00073(Rhv) | 4 | PRO B 56LEU B 91GLY B 90PRO B 247 | None | 0.94A | 1ya4A-1mqtB:undetectable | 1ya4A-1mqtB:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfi | I-KAPPA-B-ALPHA (Homo sapiens) |
PF00023(Ank)PF12796(Ank_2) | 4 | PRO E 137LEU E 163GLY E 161LEU E 131 | None | 0.79A | 1ya4A-1nfiE:undetectable | 1ya4A-1nfiE:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1puc | P13SUC1 (Schizosaccharomycespombe) |
PF01111(CKS) | 4 | PRO A 52LEU A 74GLY A 75LEU A 10 | None | 0.85A | 1ya4A-1pucA:undetectable | 1ya4A-1pucA:10.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qb3 | CYCLIN-DEPENDENTKINASES REGULATORYSUBUNIT (Saccharomycescerevisiae) |
PF01111(CKS) | 4 | PRO A 55LEU A 77GLY A 78LEU A 13 | None | 0.82A | 1ya4A-1qb3A:undetectable | 1ya4A-1qb3A:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1svc | PROTEIN (NUCLEARFACTOR KAPPA-B(NF-KB)) (Homo sapiens) |
PF00554(RHD_DNA_bind)PF16179(RHD_dimer) | 4 | PRO P 83LEU P 140GLY P 141LEU P 215 | None | 0.93A | 1ya4A-1svcP:undetectable | 1ya4A-1svcP:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t61 | TYPE IV COLLAGEN (Bos taurus) |
PF01413(C4) | 4 | MET A 145LEU A 47GLY A 48LEU A 165 | None | 0.85A | 1ya4A-1t61A:undetectable | 1ya4A-1t61A:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u6z | EXOPOLYPHOSPHATASE (Escherichiacoli) |
PF02541(Ppx-GppA) | 4 | LEU A 441GLY A 442LEU A 486PRO A 455 | None | 0.74A | 1ya4A-1u6zA:undetectable | 1ya4A-1u6zA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urj | MAJOR DNA-BINDINGPROTEIN (Humanalphaherpesvirus1) |
PF00747(Viral_DNA_bp) | 4 | LEU A 672GLY A 673LEU A 668PRO A 247 | None | 0.92A | 1ya4A-1urjA:undetectable | 1ya4A-1urjA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uyv | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF01039(Carboxyl_trans) | 4 | LEU A1860GLY A1859LEU A1950PRO A1835 | None | 0.95A | 1ya4A-1uyvA:undetectable | 1ya4A-1uyvA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xeu | INTERNALIN C (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 4 | LEU A 180GLY A 181LEU A 189PRO A 238 | None | 0.86A | 1ya4A-1xeuA:undetectable | 1ya4A-1xeuA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xkw | FE(III)-PYOCHELINRECEPTOR (Pseudomonasaeruginosa) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | LEU A 536GLY A 583LEU A 538PRO A 76 | LDA A2002 (-4.9A)NoneLDA A2001 ( 4.5A)None | 0.94A | 1ya4A-1xkwA:undetectable | 1ya4A-1xkwA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yzw | GFP-LIKENON-FLUORESCENTCHROMOPROTEIN (Heteractiscrispa) |
PF01353(GFP) | 4 | LEU A 5GLY A 4LEU A 111PRO A 35 | None | 0.76A | 1ya4A-1yzwA:undetectable | 1ya4A-1yzwA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z0u | PROBABLE INORGANICPOLYPHOSPHATE/ATP-NAD KINASE (Archaeoglobusfulgidus) |
PF01513(NAD_kinase) | 4 | PRO A 169LEU A 75GLY A 74LYS A 244 | NoneNAP A3076 (-4.3A)NAP A3076 ( 4.9A)None | 0.81A | 1ya4A-1z0uA:2.5 | 1ya4A-1z0uA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ch1 | 3-HYDROXYKYNURENINETRANSAMINASE (Anophelesgambiae) |
PF00266(Aminotran_5) | 4 | PRO A 215LEU A 207GLY A 208LEU A 268 | None | 0.94A | 1ya4A-2ch1A:undetectable | 1ya4A-2ch1A:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6e | 5'-NUCLEOTIDASE SURE (Thermusthermophilus) |
PF01975(SurE) | 4 | LEU A 119GLY A 117LEU A 229PRO A 158 | None | 0.82A | 1ya4A-2e6eA:undetectable | 1ya4A-2e6eA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hb6 | LEUCINEAMINOPEPTIDASE 1 (Caenorhabditiselegans) |
PF00883(Peptidase_M17) | 4 | PRO A 103LEU A 17GLY A 16LEU A 71 | None | 0.85A | 1ya4A-2hb6A:3.0 | 1ya4A-2hb6A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hmf | PROBABLEASPARTOKINASE (Methanocaldococcusjannaschii) |
PF00696(AA_kinase)PF01842(ACT)PF13840(ACT_7) | 4 | PRO A 188LEU A 151GLY A 153LEU A 178 | None | 0.74A | 1ya4A-2hmfA:undetectable | 1ya4A-2hmfA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pok | PEPTIDASE,M20/M25/M40 FAMILY (Streptococcuspneumoniae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | PRO A 303LEU A 251GLY A 250LEU A 339 | None | 0.85A | 1ya4A-2pokA:2.3 | 1ya4A-2pokA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyj | DNA POLYMERASE (Bacillus virusphi29) |
PF03175(DNA_pol_B_2) | 4 | TRP A 81GLY A 67LEU A 74PRO A 404 | None | 0.85A | 1ya4A-2pyjA:undetectable | 1ya4A-2pyjA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rd5 | ACETYLGLUTAMATEKINASE-LIKE PROTEIN (Arabidopsisthaliana) |
PF00696(AA_kinase) | 4 | PRO A 177LEU A 134GLY A 136LEU A 167 | None | 0.69A | 1ya4A-2rd5A:undetectable | 1ya4A-2rd5A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rkb | SERINEDEHYDRATASE-LIKE (Homo sapiens) |
PF00291(PALP) | 4 | PRO A 166LEU A 186GLY A 185LEU A 169 | None | 0.94A | 1ya4A-2rkbA:undetectable | 1ya4A-2rkbA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v0f | CHROMODOMAIN-HELICASE-DNA-BINDINGPROTEIN 7 (Homo sapiens) |
PF07533(BRK) | 4 | TRP A2685LEU A2704GLY A2706PRO A2633 | None | 0.92A | 1ya4A-2v0fA:undetectable | 1ya4A-2v0fA:11.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v7b | BENZOATE-COENZYME ALIGASE (Paraburkholderiaxenovorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | PRO A 87GLY A 239LEU A 256PRO A 247 | None | 0.79A | 1ya4A-2v7bA:2.6 | 1ya4A-2v7bA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x17 | PUTATIVE FERRITINHOMOLOG (Pyrococcusfuriosus) |
PF00210(Ferritin) | 4 | PRO 0 83LEU 0 36GLY 0 38LEU 0 151 | None | 0.90A | 1ya4A-2x170:undetectable | 1ya4A-2x170:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdq | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT B (Thermosynechococcuselongatus) |
PF00148(Oxidored_nitro) | 4 | PRO B 246MET B 247LEU B 188PRO B 408 | None | 0.92A | 1ya4A-2xdqB:undetectable | 1ya4A-2xdqB:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y0h | PROBABLE PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | PRO A 113LEU A 180GLY A 198LEU A 150 | None | 0.77A | 1ya4A-2y0hA:undetectable | 1ya4A-2y0hA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c3p | METHYLTRANSFERASE (Geobactersulfurreducens) |
PF01596(Methyltransf_3) | 4 | LEU A 142GLY A 138LEU A 155PRO A 62 | None | 0.78A | 1ya4A-3c3pA:undetectable | 1ya4A-3c3pA:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cav | 3-OXO-5-BETA-STEROID4-DEHYDROGENASE (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | PRO A 189LEU A 185GLY A 184LYS A 182 | None | 0.91A | 1ya4A-3cavA:undetectable | 1ya4A-3cavA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cc1 | PUTATIVEALPHA-N-ACETYLGALACTOSAMINIDASE (Bacillushalodurans) |
PF16499(Melibiase_2) | 4 | MET A 315LEU A 276GLY A 277LEU A 331 | None | 0.94A | 1ya4A-3cc1A:undetectable | 1ya4A-3cc1A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE ALPHA SUBUNIT (Methanosarcinabarkeri) |
PF03063(Prismane) | 4 | PRO A 692LEU A 621GLY A 617LEU A 695 | None | 0.75A | 1ya4A-3cf4A:2.1 | 1ya4A-3cf4A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8p | ACETYLTRANSFERASE OFGNAT FAMILY (Staphylococcusaureus) |
PF13673(Acetyltransf_10) | 4 | TRP A 55LEU A 99GLY A 95LEU A 80 | NoneNoneEDO A 168 ( 4.4A)EDO A 167 (-4.4A) | 0.68A | 1ya4A-3d8pA:undetectable | 1ya4A-3d8pA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e6q | PUTATIVE5-CARBOXYMETHYL-2-HYDROXYMUCONATEISOMERASE (Pseudomonasaeruginosa) |
PF02962(CHMI) | 4 | PRO A 2LEU A 80GLY A 81LEU A 29 | None | 0.83A | 1ya4A-3e6qA:undetectable | 1ya4A-3e6qA:13.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3epd | PROTEIN VP2 (Enterovirus C) |
PF00073(Rhv) | 4 | PRO 2 56LEU 2 91GLY 2 90PRO 2 254 | None | 0.92A | 1ya4A-3epd2:undetectable | 1ya4A-3epd2:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3epf | PROTEIN VP2 (Enterovirus C) |
PF00073(Rhv) | 4 | PRO 2 56LEU 2 91GLY 2 90PRO 2 254 | None | 0.95A | 1ya4A-3epf2:undetectable | 1ya4A-3epf2:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hcj | PEPTIDE METHIONINESULFOXIDE REDUCTASE (Xanthomonascampestris) |
PF01641(SelR) | 4 | LEU A 109GLY A 110LEU A 131PRO A 74 | None | 0.83A | 1ya4A-3hcjA:undetectable | 1ya4A-3hcjA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hdo | HISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Geobactermetallireducens) |
PF00155(Aminotran_1_2) | 4 | PRO A 112LEU A 133GLY A 135LEU A 160 | None | 0.81A | 1ya4A-3hdoA:undetectable | 1ya4A-3hdoA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkz | DNA-DIRECTED RNAPOLYMERASE SUBUNIT B (Sulfolobussolfataricus) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 4 | PRO B 148LEU B 23GLY B 22LEU B 423 | None | 0.95A | 1ya4A-3hkzB:undetectable | 1ya4A-3hkzB:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hvd | PROTECTIVE ANTIGEN (Bacillusanthracis) |
PF03495(Binary_toxB)PF17475(Binary_toxB_2)PF17476(Binary_toxB_3) | 4 | LEU A 187GLY A 191LEU A 203PRO A 254 | None | 0.73A | 1ya4A-3hvdA:undetectable | 1ya4A-3hvdA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2j | PROTEIN VP2 (Enterovirus B) |
PF00073(Rhv) | 4 | PRO C 47LEU C 82GLY C 81PRO C 238 | None | 0.91A | 1ya4A-3j2jC:undetectable | 1ya4A-3j2jC:18.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k9b | LIVERCARBOXYLESTERASE 1 (Homo sapiens) |
PF00135(COesterase) | 4 | PRO A1360MET A1361LEU A1368LEU A1418 | None | 0.80A | 1ya4A-3k9bA:69.0 | 1ya4A-3k9bA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k9b | LIVERCARBOXYLESTERASE 1 (Homo sapiens) |
PF00135(COesterase) | 5 | TRP A1357PRO A1360LEU A1368LEU A1418PRO A1461 | None | 0.57A | 1ya4A-3k9bA:69.0 | 1ya4A-3k9bA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m6m | RPFF PROTEINSENSORY/REGULATORYPROTEIN RPFC (Xanthomonascampestris) |
PF00072(Response_reg)PF00378(ECH_1) | 4 | MET D 530LEU A 136GLY A 137LEU A 194 | NoneNoneEDO A 902 (-3.6A)None | 0.83A | 1ya4A-3m6mD:3.0 | 1ya4A-3m6mD:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mso | STEROIDDELTA-ISOMERASE (Pseudomonasaeruginosa) |
PF12680(SnoaL_2) | 4 | MET A 56LEU A 29GLY A 28LEU A 33 | None | 0.81A | 1ya4A-3msoA:undetectable | 1ya4A-3msoA:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mzk | PROTEIN TRANSPORTPROTEIN SEC16 (Saccharomycescerevisiae) |
PF12931(Sec16_C)PF12932(Sec16) | 4 | MET B1134LEU B1128LYS B1155LEU B1151 | None | 0.94A | 1ya4A-3mzkB:undetectable | 1ya4A-3mzkB:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfd | ACYL-COADEHYDROGENASE (Mycolicibacteriumthermoresistibile) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | LEU A 107GLY A 111LYS A 116LEU A 120 | None | 0.91A | 1ya4A-3pfdA:undetectable | 1ya4A-3pfdA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtp | ENOLASE 1 (Entamoebahistolytica) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 279GLY A 278LYS A 274LEU A 259 | None | 0.71A | 1ya4A-3qtpA:undetectable | 1ya4A-3qtpA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qy2 | CYCLIN-DEPENDENTKINASES REGULATORYSUBUNIT (Saccharomycescerevisiae) |
PF01111(CKS) | 4 | PRO A 55LEU A 77GLY A 78LEU A 13 | None | 0.80A | 1ya4A-3qy2A:undetectable | 1ya4A-3qy2A:12.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3slk | POLYKETIDE SYNTHASEEXTENDER MODULE 2 (Saccharopolysporaspinosa) |
PF08240(ADH_N)PF08659(KR)PF13602(ADH_zinc_N_2) | 4 | TRP A 682GLY A 599LYS A 621LEU A 663 | NoneNDP A 802 (-3.7A)NDP A 802 (-2.5A)None | 0.91A | 1ya4A-3slkA:2.5 | 1ya4A-3slkA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tex | PROTECTIVE ANTIGEN (Bacillusanthracis) |
PF03495(Binary_toxB)PF07691(PA14)PF17475(Binary_toxB_2)PF17476(Binary_toxB_3) | 4 | LEU A 187GLY A 191LEU A 203PRO A 254 | None | 0.69A | 1ya4A-3texA:undetectable | 1ya4A-3texA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v30 | DNA-BINDING PROTEINRFXANK (Homo sapiens) |
PF12796(Ank_2)PF13606(Ank_3) | 4 | PRO A 150LEU A 176GLY A 174LEU A 144 | None | 0.94A | 1ya4A-3v30A:undetectable | 1ya4A-3v30A:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8v | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE L (Escherichiacoli) |
PF01170(UPF0020)PF02926(THUMP)PF10672(Methyltrans_SAM) | 4 | PRO A 310LEU A 329GLY A 330LEU A 344 | None | 0.92A | 1ya4A-3v8vA:undetectable | 1ya4A-3v8vA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5a | NUCLEOSIDE-TRIPHOSPHATASE 1 (Toxoplasmagondii) |
PF01150(GDA1_CD39) | 4 | MET A 325LEU A 335GLY A 334LEU A 453 | None | 0.91A | 1ya4A-4a5aA:undetectable | 1ya4A-4a5aA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4amm | DYNE8 (Micromonosporachersina) |
PF00698(Acyl_transf_1) | 4 | PRO A 644LEU A 860GLY A 856LEU A 637 | None | 0.89A | 1ya4A-4ammA:undetectable | 1ya4A-4ammA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ays | AMYLOSUCRASE (Deinococcusradiodurans) |
PF00128(Alpha-amylase) | 4 | LEU A 114GLY A 115LEU A 547PRO A 485 | None | 0.92A | 1ya4A-4aysA:undetectable | 1ya4A-4aysA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ce5 | AT-OMEGATA (Aspergillusterreus) |
PF01063(Aminotran_4) | 4 | PRO A 202LEU A 187GLY A 185LEU A 204 | None | 0.93A | 1ya4A-4ce5A:undetectable | 1ya4A-4ce5A:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cmf | AMINOTRANSFERASE ([Nectria]haematococca) |
PF01063(Aminotran_4) | 4 | PRO A 201LEU A 186GLY A 184LEU A 203 | None | 0.93A | 1ya4A-4cmfA:undetectable | 1ya4A-4cmfA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp8 | ALLOPHANATEHYDROLASE (Pseudomonas sp.ADP) |
PF01425(Amidase) | 4 | MET A 386LEU A 456GLY A 457LEU A 297 | None | 0.86A | 1ya4A-4cp8A:undetectable | 1ya4A-4cp8A:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d1e | ALPHA-ACTININ-2 (Homo sapiens) |
PF00307(CH)PF00435(Spectrin)PF08726(EFhand_Ca_insen) | 4 | LEU A 186GLY A 183LEU A 229PRO A 240 | NoneMLZ A 181 ( 4.3A)NoneMLZ A 239 ( 2.6A) | 0.95A | 1ya4A-4d1eA:undetectable | 1ya4A-4d1eA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dol | AT1G53520 (Arabidopsisthaliana) |
PF02431(Chalcone) | 4 | PRO A 30LEU A 173GLY A 172LEU A 155 | None | 0.90A | 1ya4A-4dolA:undetectable | 1ya4A-4dolA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fsp | PROBABLE PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | PRO A 112LEU A 183GLY A 201LEU A 149 | None | 0.76A | 1ya4A-4fspA:undetectable | 1ya4A-4fspA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gb3 | COAT PROTEIN 2 (Enterovirus B) |
PF00073(Rhv) | 4 | PRO 2 56LEU 2 91GLY 2 90PRO 2 249 | None | 0.86A | 1ya4A-4gb32:undetectable | 1ya4A-4gb32:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jn7 | ENOLASE (Agrobacteriumtumefaciens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | PRO A 218LEU A 230GLY A 228LEU A 238 | None | 0.91A | 1ya4A-4jn7A:2.6 | 1ya4A-4jn7A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kxz | GC1008 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | PRO H 133LEU H 196GLY H 197LEU H 145 | None | 0.92A | 1ya4A-4kxzH:undetectable | 1ya4A-4kxzH:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ldz | TRANSCRIPTIONALREGULATORY PROTEINDESR (Bacillussubtilis) |
PF00072(Response_reg)PF00196(GerE) | 4 | MET A 53LEU A 17GLY A 18LEU A 109 | None | 0.61A | 1ya4A-4ldzA:3.6 | 1ya4A-4ldzA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4le1 | TRANSCRIPTIONALREGULATORY PROTEINDESR (Bacillussubtilis) |
PF00072(Response_reg) | 4 | MET A 53LEU A 17GLY A 18LEU A 109 | None | 0.87A | 1ya4A-4le1A:3.7 | 1ya4A-4le1A:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lx1 | UNCONVENTIONALMYOSIN-VA (Homo sapiens) |
PF01843(DIL) | 4 | PRO A1507LEU A1845GLY A1846LEU A1493 | None | 0.89A | 1ya4A-4lx1A:undetectable | 1ya4A-4lx1A:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nwp | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF02962(CHMI) | 4 | PRO E 2LEU E 80GLY E 81LEU E 29 | SO4 E 204 (-4.2A)NoneNoneNone | 0.91A | 1ya4A-4nwpE:undetectable | 1ya4A-4nwpE:13.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nxk | ABP, A GH27BETA-L-ARABINOPYRANOSIDASE (Geobacillusstearothermophilus) |
PF16499(Melibiase_2) | 4 | MET A 329LEU A 290GLY A 291LEU A 345 | None | 0.95A | 1ya4A-4nxkA:undetectable | 1ya4A-4nxkA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r04 | TOXIN A (Clostridioidesdifficile) |
PF11713(Peptidase_C80)PF12918(TcdB_N)PF12919(TcdA_TcdB)PF12920(TcdA_TcdB_pore) | 4 | PRO A1137LEU A1166GLY A1167PRO A1225 | None | 0.83A | 1ya4A-4r04A:undetectable | 1ya4A-4r04A:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ras | OXIDOREDUCTASE,NAD-BINDING/IRON-SULFUR CLUSTER-BINDINGPROTEIN (Nitratireductorpacificus) |
PF12838(Fer4_7)PF13486(Dehalogenase) | 4 | LEU A 363GLY A 360LEU A 46PRO A 127 | None | 0.92A | 1ya4A-4rasA:0.0 | 1ya4A-4rasA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ric | FANCONI-ASSOCIATEDNUCLEASE 1 (Homo sapiens) |
PF08774(VRR_NUC) | 4 | LEU A 916GLY A 843LEU A 870PRO A 585 | None | 0.89A | 1ya4A-4ricA:2.6 | 1ya4A-4ricA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3p | 4-ALPHA-GLUCANOTRANSFERASE (Escherichiacoli) |
PF02446(Glyco_hydro_77) | 4 | LEU A 621GLY A 620LEU A 590PRO A 533 | None | 0.85A | 1ya4A-4s3pA:undetectable | 1ya4A-4s3pA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tll | RECEPTOR SUBUNITGLUN2B (Xenopus laevis) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 4 | PRO B 117LEU B 119GLY B 291LEU B 334 | None | 0.94A | 1ya4A-4tllB:undetectable | 1ya4A-4tllB:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4trq | NUCLEAR MRNA EXPORTPROTEIN THP1 (Saccharomycescerevisiae) |
PF01399(PCI) | 4 | PRO B 273MET B 271LEU B 231LEU B 330 | None | 0.86A | 1ya4A-4trqB:undetectable | 1ya4A-4trqB:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xny | HEAVY CHAIN OFANTIBODY VRC08C (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | PRO H 126LEU H 189GLY H 190LEU H 138 | None | 0.96A | 1ya4A-4xnyH:undetectable | 1ya4A-4xnyH:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xpr | ALPHA-GLUCOSIDASE (Pseudopedobactersaltans) |
PF01055(Glyco_hydro_31)PF17137(DUF5110) | 4 | PRO A 633MET A 634GLY A 710LEU A 664 | NoneEDO A1004 ( 4.8A)NoneNone | 0.91A | 1ya4A-4xprA:undetectable | 1ya4A-4xprA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xyw | O-ANTIGENBIOSYNTHESISGLYCOSYLTRANSFERASEWBNH (Escherichiacoli) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 4 | TRP A 19LEU A 258GLY A 257LEU A 263 | None | 0.91A | 1ya4A-4xywA:3.2 | 1ya4A-4xywA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ztx | COBALAMIN-INDEPENDENT METHIONINESYNTHASE (Neurosporacrassa) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | PRO A 735LEU A 751GLY A 749LEU A 739 | None | 0.84A | 1ya4A-4ztxA:undetectable | 1ya4A-4ztxA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7s | CYSTEINE DESULFURASE (Thermococcusonnurineus) |
PF00266(Aminotran_5) | 4 | PRO A 218MET A 219LEU A 277GLY A 273 | LLP A 216 ( 4.0A)NoneNoneNone | 0.86A | 1ya4A-5b7sA:undetectable | 1ya4A-5b7sA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csl | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2)PF08326(ACC_central) | 4 | LEU A1860GLY A1859LEU A1950PRO A1835 | None | 0.87A | 1ya4A-5cslA:undetectable | 1ya4A-5cslA:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e94 | ANTIBODY FABFRAGMENT HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | PRO B 136LEU B 199GLY B 200LEU B 148 | None | 0.83A | 1ya4A-5e94B:undetectable | 1ya4A-5e94B:17.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fv4 | CARBOXYLIC ESTERHYDROLASE (Sus scrofa) |
PF00135(COesterase) | 4 | TRP A 339PRO A 342GLY A 352LEU A 399 | None | 0.46A | 1ya4A-5fv4A:66.5 | 1ya4A-5fv4A:78.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5fv4 | CARBOXYLIC ESTERHYDROLASE (Sus scrofa) |
PF00135(COesterase) | 5 | TRP A 339PRO A 342LEU A 349LEU A 399PRO A 442 | None | 0.59A | 1ya4A-5fv4A:66.5 | 1ya4A-5fv4A:78.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gy3 | GLUCANASE (Klebsiellapneumoniae) |
PF01270(Glyco_hydro_8) | 4 | TRP A 326LEU A 324LEU A 61PRO A 308 | None | 0.89A | 1ya4A-5gy3A:undetectable | 1ya4A-5gy3A:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hm5 | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 4 | LEU A 760GLY A 759LYS A 796LEU A 792 | None | 0.87A | 1ya4A-5hm5A:undetectable | 1ya4A-5hm5A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ho9 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF16369(GH43_C) | 4 | PRO A 578LEU A 565GLY A 566LEU A 563 | SO4 A 710 (-4.0A)NoneNoneNone | 0.95A | 1ya4A-5ho9A:undetectable | 1ya4A-5ho9A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hp6 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF13385(Laminin_G_3)PF16369(GH43_C) | 4 | PRO A 578LEU A 565GLY A 566LEU A 563 | None | 0.92A | 1ya4A-5hp6A:undetectable | 1ya4A-5hp6A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdm | MAJOR TEGUMENTPROTEIN (Humangammaherpesvirus4) |
PF12818(Tegument_dsDNA) | 4 | LEU D 551GLY D 550LEU D 466PRO D 572 | None | 0.95A | 1ya4A-5kdmD:undetectable | 1ya4A-5kdmD:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2r | FUMARATE HYDRATASE (Leishmaniamajor) |
PF05681(Fumerase)PF05683(Fumerase_C) | 4 | PRO A 446LEU A 510GLY A 511LEU A 413 | None | 0.74A | 1ya4A-5l2rA:undetectable | 1ya4A-5l2rA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l56 | PLEXIN-A1 (Mus musculus) |
PF01403(Sema)PF01437(PSI)PF01833(TIG) | 4 | PRO A1176GLY A1060LEU A1184PRO A1053 | None | 0.83A | 1ya4A-5l56A:undetectable | 1ya4A-5l56A:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8q | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homo sapiens) |
no annotation | 4 | PRO A 639LEU A 880GLY A 830LEU A 627 | None | 0.95A | 1ya4A-5u8qA:undetectable | 1ya4A-5u8qA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udm | PHAGE-ASSOCIATEDCELL WALL HYDROLASE (Streptococcuspyogenes) |
no annotation | 4 | TRP B 48MET B 184GLY B 37LEU B 54 | None | 0.92A | 1ya4A-5udmB:undetectable | 1ya4A-5udmB:10.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uff | RBC36 (Petromyzonmarinus) |
no annotation | 4 | LEU A 85GLY A 86LEU A 64PRO A 113 | None | 0.90A | 1ya4A-5uffA:undetectable | 1ya4A-5uffA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyl | INNER TEGUMENTPROTEIN (Humanalphaherpesvirus1) |
PF03970(Herpes_UL37_1) | 4 | LEU A 113GLY A 112LEU A 533PRO A 227 | None | 0.80A | 1ya4A-5vylA:undetectable | 1ya4A-5vylA:23.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w1u | CARBOXYLIC ESTERHYDROLASE (Culexquinquefasciatus) |
PF00135(COesterase) | 4 | MET A 529GLY A 397LEU A 539PRO A 350 | None | 0.77A | 1ya4A-5w1uA:39.2 | 1ya4A-5w1uA:30.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xpg | UNCHARACTERIZEDPROTEIN (Thermusthermophilus) |
no annotation | 4 | LEU A 455GLY A 453LEU A 346PRO A 431 | None | 0.96A | 1ya4A-5xpgA:undetectable | 1ya4A-5xpgA:10.78 |