SIMILAR PATTERNS OF AMINO ACIDS FOR 1XR2_B_C2FB1201_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bm8 | TRANSCRIPTION FACTORMBP1 (Saccharomycescerevisiae) |
PF04383(KilA-N) | 4 | SER A 11ARG A 9TRP A 77GLU A 64 | None | 1.22A | 1xr2B-1bm8A:0.0 | 1xr2B-1bm8A:8.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ehi | D-ALANINE:D-LACTATELIGASE (Leuconostocmesenteroides) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 4 | LYS A 180THR A 244SER A 187GLU A 216 | ADP A 781 (-2.6A)NoneADP A 781 (-3.5A)ADP A 781 (-3.7A) | 1.42A | 1xr2B-1ehiA:0.0 | 1xr2B-1ehiA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kut | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (Thermotogamaritima) |
PF01259(SAICAR_synt) | 4 | LYS A 170THR A 71SER A 188GLU A 172 | None | 1.29A | 1xr2B-1kutA:0.0 | 1xr2B-1kutA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mb1 | MLU1-BOX BINDINGPROTEIN (Saccharomycescerevisiae) |
PF04383(KilA-N) | 4 | SER A 11ARG A 9TRP A 77GLU A 64 | None | 1.22A | 1xr2B-1mb1A:0.0 | 1xr2B-1mb1A:10.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1u1h | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Arabidopsisthaliana) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | LYS A 18TRP A 514SER A 517TRP A 567 | None | 0.62A | 1xr2B-1u1hA:48.3 | 1xr2B-1u1hA:41.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xpg | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Thermotogamaritima) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 8 | LYS A 18LYS A 104THR A 466TRP A 486SER A 489ARG A 493TRP A 539GLU A 583 | C2F A1882 (-2.4A)C2F A1882 ( 3.3A)NoneNoneC2F A1882 (-3.0A)C2F A1882 ( 3.5A)C2F A1882 (-3.7A)C2F A1882 (-3.0A) | 0.73A | 1xr2B-1xpgA:64.2 | 1xr2B-1xpgA:99.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w37 | ORNITHINECARBAMOYLTRANSFERASE, CATABOLIC (Lactobacillushilgardii) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | LYS A 37THR A 180SER A 326GLU A 153 | None | 1.48A | 1xr2B-2w37A:0.5 | 1xr2B-2w37A:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xtz | GUANINENUCLEOTIDE-BINDINGPROTEIN ALPHA-1SUBUNIT (Arabidopsisthaliana) |
PF00503(G-alpha) | 4 | LYS A 59LYS A 288THR A 194GLU A 247 | NoneGSP A1382 (-3.1A)NoneNone | 1.48A | 1xr2B-2xtzA:1.7 | 1xr2B-2xtzA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | LYS A1248THR A 209SER A 70ARG A 226 | ALF A 501 (-2.1A)NoneADP A 502 (-2.9A)None | 1.08A | 1xr2B-3cmuA:undetectable | 1xr2B-3cmuA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | LYS A2248THR A1209SER A1070ARG A1226 | ALF A1501 (-2.3A)NoneADP A1502 (-2.9A)None | 1.07A | 1xr2B-3cmuA:undetectable | 1xr2B-3cmuA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | LYS A3248THR A2209SER A2070ARG A2226 | ALF A2501 (-2.2A)NoneADP A2502 (-2.6A)None | 1.08A | 1xr2B-3cmuA:undetectable | 1xr2B-3cmuA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | LYS A4248THR A3209SER A3070ARG A3226 | ALF A3501 (-2.3A)NoneADP A3502 (-2.7A)None | 1.06A | 1xr2B-3cmuA:undetectable | 1xr2B-3cmuA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | LYS A5248THR A4209SER A4070ARG A4226 | ALF A4501 (-2.6A)NoneADP A4502 (-2.7A)None | 1.07A | 1xr2B-3cmuA:undetectable | 1xr2B-3cmuA:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3czp | PUTATIVEPOLYPHOSPHATE KINASE2 (Pseudomonasaeruginosa) |
PF03976(PPK2) | 4 | LYS A 311TRP A 408SER A 364ARG A 363 | GOL A 610 (-4.9A)NoneNoneNone | 1.25A | 1xr2B-3czpA:undetectable | 1xr2B-3czpA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ho8 | PYRUVATE CARBOXYLASE (Staphylococcusaureus) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | LYS A 741THR A 611SER A 806GLU A 849 | MN A2002 (-3.1A)NoneNoneNone | 1.31A | 1xr2B-3ho8A:9.2 | 1xr2B-3ho8A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ld8 | BIFUNCTIONALARGININE DEMETHYLASEANDLYSYL-HYDROXYLASEJMJD6 (Homo sapiens) |
PF02373(JmjC) | 4 | LYS A 100THR A 193SER A 135GLU A 103 | SO4 A 343 ( 4.7A)NoneSO4 A 343 ( 4.9A)None | 1.31A | 1xr2B-3ld8A:undetectable | 1xr2B-3ld8A:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nib | TEG14 (uncultured soilbacterium) |
PF00685(Sulfotransfer_1) | 4 | LYS A 65SER A 9ARG A 90GLU A 43 | NoneNoneGOL A 278 (-3.4A)None | 1.39A | 1xr2B-3nibA:undetectable | 1xr2B-3nibA:17.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ppc | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Candidaalbicans) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | LYS A 19TRP A 523SER A 526GLU A 620 | None | 0.90A | 1xr2B-3ppcA:48.8 | 1xr2B-3ppcA:42.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ppc | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Candidaalbicans) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | LYS A 19TRP A 523SER A 526TRP A 576 | None | 0.59A | 1xr2B-3ppcA:48.8 | 1xr2B-3ppcA:42.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbk | RIG-I HELICASEDOMAIN (Mus musculus) |
PF00271(Helicase_C)PF04851(ResIII) | 4 | LYS A 611LYS A 751THR A 507SER A 745 | None | 1.21A | 1xr2B-3tbkA:undetectable | 1xr2B-3tbkA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3top | MALTASE-GLUCOAMYLASE, INTESTINAL (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 4 | LYS A1460THR A1528SER A1166GLU A1543 | ACR A 1 ( 3.7A)ACR A 1 ( 4.6A)NoneNone | 1.42A | 1xr2B-3topA:8.0 | 1xr2B-3topA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tvi | ASPARTOKINASE (Clostridiumacetobutylicum) |
PF00696(AA_kinase)PF01842(ACT) | 4 | LYS A 294SER A 238ARG A 235GLU A 343 | None | 1.16A | 1xr2B-3tviA:3.5 | 1xr2B-3tviA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4a | JMB19063 (compostmetagenome) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | THR A 197SER A 491ARG A 139GLU A 145 | None | 1.44A | 1xr2B-3u4aA:4.6 | 1xr2B-3u4aA:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eel | BETA-PHOSPHOGLUCOMUTASE-RELATED PROTEIN (Deinococcusradiodurans) |
PF13419(HAD_2) | 4 | LYS A 146THR A 88SER A 113GLU A 170 | CIT A 301 (-2.8A)NoneCIT A 301 (-3.3A)CIT A 301 ( 4.5A) | 1.30A | 1xr2B-4eelA:undetectable | 1xr2B-4eelA:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1n | KPAGO (Vanderwaltozymapolyspora) |
PF02171(Piwi) | 4 | LYS A 432SER A 336ARG A 325GLU A 341 | None | 1.25A | 1xr2B-4f1nA:3.5 | 1xr2B-4f1nA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kr9 | PROBABLE TRNASULFURTRANSFERASE (Thermotogamaritima) |
PF02568(ThiI)PF02926(THUMP) | 4 | LYS A 60THR A 332SER A 231GLU A 202 | None | 1.43A | 1xr2B-4kr9A:undetectable | 1xr2B-4kr9A:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5o | POLYMERASE PA (Influenza Avirus) |
PF00603(Flu_PA) | 4 | TRP A 188SER A 194ARG A 125GLU A 26 | NoneEDO A 305 (-4.0A)NoneX48 A 308 (-3.5A) | 1.02A | 1xr2B-4m5oA:undetectable | 1xr2B-4m5oA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nes | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Methanocaldococcusjannaschii) |
PF02350(Epimerase_2) | 4 | THR A 96SER A 122ARG A 311GLU A 157 | UD1 A 400 (-4.1A)NoneNoneNone | 1.49A | 1xr2B-4nesA:2.6 | 1xr2B-4nesA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nxk | ABP, A GH27BETA-L-ARABINOPYRANOSIDASE (Geobacillusstearothermophilus) |
PF16499(Melibiase_2) | 4 | THR A 319TRP A 340TRP A 260GLU A 390 | None | 1.49A | 1xr2B-4nxkA:undetectable | 1xr2B-4nxkA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzs | SIMILARITY TOHELICASE MOT1ECU04_1440 PROTEIN (Encephalitozooncuniculi;Encephalitozooncuniculi) |
no annotationPF00352(TBP) | 4 | LYS D 41LYS C 168SER C 91GLU C 144 | None | 1.30A | 1xr2B-4wzsD:undetectable | 1xr2B-4wzsD:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z4l | CELLOBIOSE2-EPIMERASE (Caldicellulosiruptorsaccharolyticus) |
PF07221(GlcNAc_2-epim) | 4 | THR A 185TRP A 98SER A 55ARG A 56 | None | 1.24A | 1xr2B-4z4lA:undetectable | 1xr2B-4z4lA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo6 | LIN1840 PROTEIN (Listeriainnocua) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | THR A 207SER A 476ARG A 146GLU A 152 | NoneNoneNoneBGC A 802 ( 4.9A) | 1.36A | 1xr2B-4zo6A:4.4 | 1xr2B-4zo6A:22.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ztx | COBALAMIN-INDEPENDENT METHIONINESYNTHASE (Neurosporacrassa) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 5 | LYS A 19LYS A 115TRP A 518SER A 521GLU A 615 | None | 1.37A | 1xr2B-4ztxA:51.5 | 1xr2B-4ztxA:40.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ztx | COBALAMIN-INDEPENDENT METHIONINESYNTHASE (Neurosporacrassa) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 5 | LYS A 19LYS A 115TRP A 518SER A 521TRP A 571 | None | 0.98A | 1xr2B-4ztxA:51.5 | 1xr2B-4ztxA:40.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3f | DYNAMIN 3 (Homo sapiens) |
PF00169(PH)PF00350(Dynamin_N)PF01031(Dynamin_M)PF02212(GED) | 4 | LYS A 376LYS A 472ARG A 369GLU A 468 | None | 1.47A | 1xr2B-5a3fA:undetectable | 1xr2B-5a3fA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5amq | RNA POLYMERASE L (Californiaencephalitisorthobunyavirus) |
PF04196(Bunya_RdRp)PF15518(L_protein_N) | 4 | THR A 811SER A 233ARG A 235GLU A 224 | None | 1.25A | 1xr2B-5amqA:undetectable | 1xr2B-5amqA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eaw | DNA REPLICATIONATP-DEPENDENTHELICASE/NUCLEASEDNA2 (Mus musculus) |
PF08696(Dna2)PF13086(AAA_11)PF13087(AAA_12) | 4 | LYS A 357SER A 88ARG A 84GLU A 354 | None | 1.43A | 1xr2B-5eawA:undetectable | 1xr2B-5eawA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eyw | TRIOSEPHOSPHATEISOMERASE (Litopenaeusvannamei) |
PF00121(TIM) | 4 | LYS A 14THR A 176SER A 97GLU A 133 | PGA A 301 (-2.7A)NoneNoneNone | 1.30A | 1xr2B-5eywA:3.6 | 1xr2B-5eywA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks8 | PYRUVATE CARBOXYLASESUBUNIT BETA (Methylobacillusflagellatus) |
PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | LYS C 174THR C 50SER C 238GLU C 281 | MN C2002 ( 2.7A)NoneNoneNone | 1.23A | 1xr2B-5ks8C:2.3 | 1xr2B-5ks8C:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tf0 | GLYCOSYL HYDROLASEFAMILY 3 N-TERMINALDOMAIN PROTEIN (Bacteroidesintestinalis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | THR A 229SER A 528ARG A 167GLU A 173 | None | 1.35A | 1xr2B-5tf0A:undetectable | 1xr2B-5tf0A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyw | PYRUVATE CARBOXYLASE (Lactococcuslactis) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | LYS A 703THR A 573SER A 767GLU A 810 | MN A1201 (-3.1A)NoneNoneNone | 1.34A | 1xr2B-5vywA:undetectable | 1xr2B-5vywA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wkn | NUCLEOPROTEIN (Mammalianrubulavirus 5) |
no annotation | 4 | LYS A 225SER A 67ARG A 69GLU A 126 | None | 1.32A | 1xr2B-5wknA:undetectable | 1xr2B-5wknA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wq8 | TYPE II SECRETIONSYSTEM PROTEIN D (Vibrio cholerae) |
PF00263(Secretin)PF03958(Secretin_N) | 4 | LYS A 483THR A 460ARG A 477GLU A 503 | None | 1.37A | 1xr2B-5wq8A:undetectable | 1xr2B-5wq8A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xzb | CYCLIC GMP-AMPSYNTHASE (Mus musculus) |
PF03281(Mab-21) | 4 | LYS A 409THR A 295SER A 420GLU A 371 | None | 1.41A | 1xr2B-5xzbA:undetectable | 1xr2B-5xzbA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y81 | TRANSCRIPTION-ASSOCIATED PROTEIN 1 (Saccharomycescerevisiae) |
no annotation | 4 | THR B2836ARG B3439TRP B3542GLU B2641 | None | 1.16A | 1xr2B-5y81B:undetectable | 1xr2B-5y81B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zib | - (-) |
no annotation | 4 | LYS A 337SER A 169ARG A 168GLU A 193 | None | 1.32A | 1xr2B-5zibA:undetectable | 1xr2B-5zibA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT C (Flavobacteriumjohnsoniae) |
no annotation | 4 | THR C 277TRP C 85SER C 122GLU C 116 | None | 1.43A | 1xr2B-6btmC:undetectable | 1xr2B-6btmC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxn | DIPHTHAMIDEBIOSYNTHESIS ENZYMEDPH2 (CandidatusMethanoperedensnitroreducens) |
no annotation | 4 | LYS A 32THR A 233SER A 53GLU A 29 | None | 1.10A | 1xr2B-6bxnA:undetectable | 1xr2B-6bxnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c5b | METHYLTRANSFERASE (Lysobacterantibioticus) |
no annotation | 4 | THR A 127SER A 258ARG A 257GLU A 311 | None | 1.12A | 1xr2B-6c5bA:undetectable | 1xr2B-6c5bA:undetectable |