SIMILAR PATTERNS OF AMINO ACIDS FOR 1XOZ_A_CIAA501_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bxz | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Thermoanaerobacterbrockii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 263ILE A 262ILE A 240VAL A 170ILE A 227 | None | 0.93A | 1xozA-1bxzA:undetectable | 1xozA-1bxzA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dqs | PROTEIN(3-DEHYDROQUINATESYNTHASE) (Aspergillusnidulans) |
PF01761(DHQ_synthase) | 5 | TYR A 323ILE A 196PHE A 188LEU A 180MET A 144 | None | 1.14A | 1xozA-1dqsA:undetectable | 1xozA-1dqsA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e5m | BETA KETOACYL ACYLCARRIER PROTEINSYNTHASE II (Synechocystissp. PCC 6803) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | ALA A 84ILE A 17ILE A 241VAL A 355LEU A 31 | None | 1.13A | 1xozA-1e5mA:undetectable | 1xozA-1e5mA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fno | PEPTIDASE T (Salmonellaenterica) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 165VAL A 167PHE A 169LEU A 38ILE A 50 | None | 1.13A | 1xozA-1fnoA:undetectable | 1xozA-1fnoA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqb | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Clostridiumbeijerinckii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A1191ILE A1194ILE A1164PHE A1156ILE A1265 | None | 1.03A | 1xozA-1jqbA:undetectable | 1xozA-1jqbA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcl | CYCLODEXTRINGLYCOSYLTRANSFERASE (Bacilluscirculans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 5 | ALA A 644GLN A 586VAL A 589PHE A 591LEU A 606 | MPD A1701 ( 4.0A)NoneNoneNoneNone | 1.05A | 1xozA-1kclA:undetectable | 1xozA-1kclA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mox | EPIDERMAL GROWTHFACTOR RECEPTOR (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 5 | ALA A 448ILE A 451ILE A 439VAL A 437ILE A 402 | None | 1.11A | 1xozA-1moxA:undetectable | 1xozA-1moxA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nhc | POLYGALACTURONASE I (Aspergillusniger) |
PF00295(Glyco_hydro_28) | 5 | ALA A 157ILE A 158PHE A 220LEU A 231ILE A 212 | None | 1.08A | 1xozA-1nhcA:undetectable | 1xozA-1nhcA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1okg | POSSIBLE3-MERCAPTOPYRUVATESULFURTRANSFERASE (Leishmaniamajor) |
PF00581(Rhodanese)PF09122(DUF1930) | 5 | TYR A 101ALA A 55ILE A 56ILE A 30LEU A 64 | None | 1.03A | 1xozA-1okgA:undetectable | 1xozA-1okgA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p8r | ARGINASE 1 (Rattusnorvegicus) |
PF00491(Arginase) | 5 | ILE A 208VAL A 123PHE A 231LEU A 299ILE A 264 | None | 0.99A | 1xozA-1p8rA:undetectable | 1xozA-1p8rA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q15 | CARA (Pectobacteriumcarotovorum) |
PF00733(Asn_synthase)PF09147(DUF1933) | 5 | ALA A 321ILE A 306ILE A 315LEU A 486ILE A 488 | None | 1.12A | 1xozA-1q15A:undetectable | 1xozA-1q15A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qmo | MANNOSE BINDINGLECTIN, FRIL (Lablabpurpureus) |
PF00139(Lectin_legB) | 5 | ALA E 180ILE A 72VAL E 137LEU A 108ILE A 92 | None | 1.13A | 1xozA-1qmoE:undetectable | 1xozA-1qmoE:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qy9 | HYPOTHETICAL PROTEINYDDE (Escherichiacoli) |
PF02567(PhzC-PhzF) | 5 | ALA A 48ILE A 60VAL A 82LEU A 87ILE A 107 | None | 1.14A | 1xozA-1qy9A:undetectable | 1xozA-1qy9A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r1a | HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP1)HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP2)HUMAN RHINOVIRUS 1ACOAT PROTEIN(SUBUNIT VP3) (Rhinovirus A) |
PF00073(Rhv) | 5 | ILE 3 44VAL 3 40PHE 1 116LEU 1 115ILE 2 185 | None | 1.14A | 1xozA-1r1a3:undetectable | 1xozA-1r1a3:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6u | TRYPTOPHANYL-TRNASYNTHETASE (Homo sapiens) |
PF00579(tRNA-synt_1b) | 5 | ALA A 285ILE A 254VAL A 258ILE A 278PHE A 267 | None | 0.99A | 1xozA-1r6uA:undetectable | 1xozA-1r6uA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urd | MALTOSE-BINDINGPROTEIN (Alicyclobacillusacidocaldarius) |
PF01547(SBP_bac_1) | 5 | ALA A 377ILE A 376GLN A 373ILE A 237MET A 172 | None | 1.03A | 1xozA-1urdA:undetectable | 1xozA-1urdA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrm | HYPOTHETICAL PROTEINTM1553 (Thermotogamaritima) |
PF02424(ApbE) | 5 | ALA A 205ILE A 204ILE A 225VAL A 216LEU A 53 | NoneMPD A 1 ( 4.2A)NoneNoneNone | 0.97A | 1xozA-1vrmA:undetectable | 1xozA-1vrmA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ys4 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Methanocaldococcusjannaschii) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 5 | ALA A 150ILE A 151GLN A 141ILE A 138MET A 119 | None | 0.86A | 1xozA-1ys4A:undetectable | 1xozA-1ys4A:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkl | HIGH-AFFINITYCAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 7A (Homo sapiens) |
PF00233(PDEase_I) | 6 | TYR A 211VAL A 380PHE A 384ILE A 409GLN A 413PHE A 416 | IBM A 503 (-4.6A)IBM A 503 (-4.7A)IBM A 503 (-4.5A)NoneIBM A 503 (-3.0A)IBM A 503 (-3.4A) | 0.82A | 1xozA-1zklA:38.4 | 1xozA-1zklA:29.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkl | HIGH-AFFINITYCAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 7A (Homo sapiens) |
PF00233(PDEase_I) | 6 | TYR A 211VAL A 380PHE A 384LEU A 401GLN A 413PHE A 416 | IBM A 503 (-4.6A)IBM A 503 (-4.7A)IBM A 503 (-4.5A)NoneIBM A 503 (-3.0A)IBM A 503 (-3.4A) | 0.87A | 1xozA-1zklA:38.4 | 1xozA-1zklA:29.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fnc | MALTOSE ABCTRANSPORTER,PERIPLASMICMALTOSE-BINDINGPROTEIN (Thermotogamaritima) |
PF13416(SBP_bac_8) | 5 | ILE A 288ILE A 9VAL A 34ILE A 279PHE A 287 | None | 0.99A | 1xozA-2fncA:undetectable | 1xozA-2fncA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ho4 | HALOACIDDEHALOGENASE-LIKEHYDROLASE DOMAINCONTAINING 2 (Mus musculus) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 5 | ALA A 250ILE A 254VAL A 12PHE A 44MET A 41 | None | 1.12A | 1xozA-2ho4A:undetectable | 1xozA-2ho4A:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3b | HUMAN CANCER-RELATEDNTPASE (Homo sapiens) |
PF03266(NTPase_1) | 5 | ILE A 138VAL A 4PHE A 166LEU A 176ILE A 18 | None | 1.05A | 1xozA-2i3bA:undetectable | 1xozA-2i3bA:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iy9 | SUBA (Escherichiacoli) |
PF00082(Peptidase_S8) | 5 | ALA A 251ILE A 249ILE A 277VAL A 281ILE A 146 | None | 1.10A | 1xozA-2iy9A:undetectable | 1xozA-2iy9A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6l | ALDEHYDEDEHYDROGENASE FAMILY7 MEMBER A1 (Homo sapiens) |
PF00171(Aldedh) | 5 | ALA A 130ILE A 126ILE A 183LEU A 267ILE A 163 | None | 1.08A | 1xozA-2j6lA:undetectable | 1xozA-2j6lA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qgh | DIAMINOPIMELATEDECARBOXYLASE (Helicobacterpylori) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 5 | ALA A 164ILE A 134VAL A 182PHE A 220LEU A 252 | None | 1.01A | 1xozA-2qghA:undetectable | 1xozA-2qghA:27.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2r8q | CLASS IPHOSPHODIESTERASEPDEB1 (Leishmaniamajor) |
PF00233(PDEase_I) | 5 | TYR A 680VAL A 853PHE A 857GLN A 887PHE A 890 | IBM A 3 ( 4.7A)IBM A 3 ( 4.8A)IBM A 3 (-4.9A)IBM A 3 (-3.3A)IBM A 3 (-3.6A) | 0.49A | 1xozA-2r8qA:40.5 | 1xozA-2r8qA:30.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xvg | ALPHA XYLOSIDASE (Cellvibriojaponicus) |
PF01055(Glyco_hydro_31)PF16338(DUF4968)PF17137(DUF5110) | 5 | ALA A 82ILE A 403VAL A 134PHE A 136LEU A 145 | None | 1.13A | 1xozA-2xvgA:undetectable | 1xozA-2xvgA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zuk | ALPHA-AMINO-EPSILON-CAPROLACTAM RACEMASE (Achromobacterobae) |
PF00202(Aminotran_3) | 5 | ALA A 280ILE A 284VAL A 236PHE A 203ILE A 233 | None | 1.00A | 1xozA-2zukA:undetectable | 1xozA-2zukA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai2 | NADPH-SORBOSEREDUCTASE (Gluconobacterfrateurii) |
PF13561(adh_short_C2) | 5 | ALA A 10ILE A 12ILE A 88VAL A 238ILE A 185 | None | 1.06A | 1xozA-3ai2A:undetectable | 1xozA-3ai2A:20.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b2r | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 11 | TYR A 612ALA A 767ILE A 768GLN A 775ILE A 778VAL A 782PHE A 786ILE A 813MET A 816GLN A 817PHE A 820 | VDN A 1 (-4.8A)VDN A 1 ( 3.8A)VDN A 1 (-4.5A)VDN A 1 ( 4.4A)NoneVDN A 1 ( 4.7A)NoneVDN A 1 ( 4.2A)VDN A 1 (-4.0A)VDN A 1 (-3.0A)VDN A 1 (-3.6A) | 0.53A | 1xozA-3b2rA:45.7 | 1xozA-3b2rA:94.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bjc | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 11 | TYR A 612ALA A 767ILE A 768GLN A 775ILE A 778VAL A 782PHE A 786ILE A 813MET A 816GLN A 817PHE A 820 | NoneWAN A 901 ( 3.9A)WAN A 901 ( 4.9A)WAN A 901 ( 4.6A)NoneWAN A 901 ( 4.9A)WAN A 901 (-4.8A)WAN A 901 ( 4.3A)WAN A 901 (-4.3A)WAN A 901 (-3.1A)WAN A 901 (-3.7A) | 0.68A | 1xozA-3bjcA:48.2 | 1xozA-3bjcA:46.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d9y | PROFILIN (Schizosaccharomycespombe) |
PF00235(Profilin) | 5 | ALA A 110ILE A 88PHE A 36LEU A 38ILE A 21 | None | 1.04A | 1xozA-3d9yA:undetectable | 1xozA-3d9yA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ddj | CBSDOMAIN-CONTAININGPROTEIN (Sulfolobussolfataricus) |
PF00571(CBS) | 5 | ALA A 96ILE A 99ILE A 3LEU A 45ILE A 42 | NoneNoneNonePEG A 279 (-4.9A)None | 1.14A | 1xozA-3ddjA:undetectable | 1xozA-3ddjA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e1k | GALACTOSE/LACTOSEMETABOLISMREGULATORY PROTEINGAL80 (Kluyveromyceslactis) |
PF01408(GFO_IDH_MocA) | 5 | ILE A 388VAL A 91PHE A 22ILE A 87PHE A 47 | None | 1.02A | 1xozA-3e1kA:undetectable | 1xozA-3e1kA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebj | POLYMERASE ACIDICPROTEIN (Influenza Avirus) |
PF00603(Flu_PA) | 5 | ALA A 17ILE A 13ILE A 38LEU A 109PHE A 46 | None | 1.08A | 1xozA-3ebjA:undetectable | 1xozA-3ebjA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ecd | SERINEHYDROXYMETHYLTRANSFERASE 2 (Burkholderiapseudomallei) |
PF00464(SHMT) | 5 | ALA A 210ILE A 209VAL A 228LEU A 202ILE A 176 | None | 0.96A | 1xozA-3ecdA:undetectable | 1xozA-3ecdA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efb | PROBABLE SOR-OPERONREGULATOR (Shigellaflexneri) |
PF04198(Sugar-bind) | 5 | ALA A 232ILE A 231ILE A 162LEU A 100ILE A 93 | None | 1.11A | 1xozA-3efbA:undetectable | 1xozA-3efbA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehc | SNOAL-LIKEPOLYKETIDE CYCLASE (Agrobacteriumfabrum) |
PF07366(SnoaL) | 5 | ALA A 121ILE A 122GLN A 125LEU A 57PHE A 85 | None | 0.95A | 1xozA-3ehcA:undetectable | 1xozA-3ehcA:16.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 5 | ALA B 135ILE B 131ILE B 243VAL B 247LEU B 370 | None | 1.00A | 1xozA-3ejbB:undetectable | 1xozA-3ejbB:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fpl | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Clostridiumbeijerinckii;Thermoanaerobacterbrockii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 263ILE A 262ILE A 240VAL A 170ILE A 227 | None | 0.88A | 1xozA-3fplA:undetectable | 1xozA-3fplA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fsr | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Clostridiumbeijerinckii;Thermoanaerobacterbrockii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 191ILE A 194ILE A 164PHE A 156ILE A 265 | None | 1.01A | 1xozA-3fsrA:undetectable | 1xozA-3fsrA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g85 | TRANSCRIPTIONALREGULATOR (LACIFAMILY) (Clostridiumacetobutylicum) |
PF13377(Peripla_BP_3) | 5 | ILE A 307ILE A 149VAL A 161PHE A 326ILE A 299 | None | 0.98A | 1xozA-3g85A:undetectable | 1xozA-3g85A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gy9 | GCN5-RELATEDN-ACETYLTRANSFERASE (Exiguobacteriumsibiricum) |
PF13673(Acetyltransf_10) | 5 | ALA A 53ILE A 5LEU A 125ILE A 78MET A 101 | None | 1.02A | 1xozA-3gy9A:undetectable | 1xozA-3gy9A:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 5 | TYR A1332ILE A1211VAL A1215LEU A1291ILE A1200 | None | 1.13A | 1xozA-3hmjA:undetectable | 1xozA-3hmjA:11.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htx | HEN1 (Arabidopsisthaliana) |
PF13847(Methyltransf_31) | 5 | ALA A 312ILE A 320ILE A 224LEU A 255ILE A 249 | None | 1.05A | 1xozA-3htxA:undetectable | 1xozA-3htxA:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | ALA A 397ILE A 394ILE A 291PHE A 256GLN A 293 | None | 0.94A | 1xozA-3i04A:undetectable | 1xozA-3i04A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3o | SHORT CHAINDEHYDROGENASE (Bacillusanthracis) |
PF13561(adh_short_C2) | 5 | TYR A 262ILE A 56VAL A 60PHE A 64ILE A 73 | NoneNAE A 311 (-3.8A)NoneNoneNone | 1.11A | 1xozA-3i3oA:undetectable | 1xozA-3i3oA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibj | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I)PF01590(GAF)PF13185(GAF_2) | 5 | TYR A 655ILE A 822ILE A 855GLN A 859PHE A 862 | None | 0.86A | 1xozA-3ibjA:38.3 | 1xozA-3ibjA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jaf | GLYCINE RECEPTORSUBUNIT ALPHAZ1 (Danio rerio) |
PF02931(Neur_chan_LBD)PF02932(Neur_chan_memb) | 5 | TYR A 357ALA A 298ILE A 299ILE A 301LEU A 248 | None | 1.07A | 1xozA-3jafA:undetectable | 1xozA-3jafA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm4 | CATECHOL2,3-DIOXYGENASE (Rhodococcusjostii) |
PF00903(Glyoxalase) | 6 | TYR A 222ALA A 231ILE A 148VAL A 150LEU A 57PHE A 27 | None | 1.35A | 1xozA-3lm4A:undetectable | 1xozA-3lm4A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxu | TRIPEPTIDYL-PEPTIDASE 2 (Drosophilamelanogaster) |
PF00082(Peptidase_S8)PF12580(TPPII)PF12583(TPPII_N) | 5 | ALA X 41ILE X 40ILE X 337VAL X 366ILE X 491 | None | 1.10A | 1xozA-3lxuX:undetectable | 1xozA-3lxuX:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qbw | ANHYDRO-N-ACETYLMURAMIC ACID KINASE (Pseudomonasaeruginosa) |
PF03702(AnmK) | 5 | ALA A 59ILE A 56ILE A 110VAL A 108PHE A 106 | None | 0.87A | 1xozA-3qbwA:undetectable | 1xozA-3qbwA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rj9 | ALCOHOLDEHYDROGENASE (Scaptodrosophilalebanonensis) |
PF00106(adh_short) | 5 | ALA A 134ILE A 133ILE A 89VAL A 8ILE A 78 | None | 1.09A | 1xozA-3rj9A:undetectable | 1xozA-3rj9A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqr | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Coxiellaburnetii) |
PF00551(Formyl_trans_N) | 5 | ILE A 111ILE A 180VAL A 184PHE A 188LEU A 86 | None | 0.89A | 1xozA-3tqrA:undetectable | 1xozA-3tqrA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tw0 | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcusagalactiae) |
PF00092(VWA) | 5 | TYR A 529ALA A 363ILE A 366ILE A 379ILE A 259 | None | 1.04A | 1xozA-3tw0A:undetectable | 1xozA-3tw0A:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v94 | CYCLIC NUCLEOTIDESPECIFICPHOSPHODIESTERASE (Trypanosomacruzi) |
PF00233(PDEase_I) | 5 | TYR A 367ALA A 524PHE A 542GLN A 570PHE A 573 | WYQ A 701 (-4.5A)NoneWYQ A 701 (-4.7A)WYQ A 701 (-3.3A)WYQ A 701 (-3.4A) | 0.68A | 1xozA-3v94A:37.1 | 1xozA-3v94A:27.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vqi | ATG5 (Kluyveromycesmarxianus) |
PF04106(APG5) | 5 | TYR A 267ILE A 262VAL A 88ILE A 13MET A 39 | None | 1.13A | 1xozA-3vqiA:undetectable | 1xozA-3vqiA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vva | ALTERNATIVE OXIDASE,MITOCHONDRIAL (Trypanosomabrucei) |
PF01786(AOX) | 5 | ALA A 226ILE A 227ILE A 110VAL A 115LEU A 172 | None | 0.84A | 1xozA-3vvaA:undetectable | 1xozA-3vvaA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zok | 3-DEHYDROQUINATESYNTHASE (Actinidiachinensis) |
PF01761(DHQ_synthase) | 5 | ALA A 283VAL A 200PHE A 211LEU A 353ILE A 205 | None | 1.06A | 1xozA-3zokA:undetectable | 1xozA-3zokA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxy | SUBTILISIN-LIKEPROTEIN (Prochlorondidemni) |
PF00082(Peptidase_S8) | 5 | ALA A 197ILE A 195ILE A 223VAL A 227ILE A 115 | None | 1.11A | 1xozA-3zxyA:undetectable | 1xozA-3zxyA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ain | GLYCINE BETAINETRANSPORTER BETP (Corynebacteriumglutamicum) |
PF02028(BCCT) | 5 | ALA A 66ILE A 69ILE A 243VAL A 247LEU A 506 | None | 0.91A | 1xozA-4ainA:undetectable | 1xozA-4ainA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzi | SEC23P (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | ALA A 269ILE A 160ILE A 284LEU A 238ILE A 144 | None | 0.99A | 1xozA-4bziA:undetectable | 1xozA-4bziA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d8m | PESTICIDAL CRYSTALPROTEIN CRY5BA (Bacillusthuringiensis) |
PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | ILE A 664ILE A 678VAL A 676PHE A 674LEU A 631 | None | 1.02A | 1xozA-4d8mA:2.5 | 1xozA-4d8mA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4djt | GTP-BINDING NUCLEARPROTEIN GSP1 (Encephalitozooncuniculi) |
PF00071(Ras) | 5 | ALA A 152ILE A 150VAL A 18LEU A 99ILE A 131 | GDP A 301 (-3.7A)NoneGDP A 301 (-3.9A)NoneNone | 1.04A | 1xozA-4djtA:undetectable | 1xozA-4djtA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4esj | TYPE-2 RESTRICTIONENZYME DPNI (Streptococcuspneumoniae) |
PF06044(DpnI) | 5 | ILE A 236GLN A 233ILE A 192PHE A 117PHE A 177 | None | 1.09A | 1xozA-4esjA:undetectable | 1xozA-4esjA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gni | PUTATIVE HEAT SHOCKPROTEIN (Chaetomiumthermophilum) |
PF00012(HSP70) | 5 | ALA A 153ILE A 155ILE A 16VAL A 139ILE A 47 | None | 1.11A | 1xozA-4gniA:undetectable | 1xozA-4gniA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h6w | N-TERMINALCYANOBACTIN PROTEASE (Planktothrixagardhii) |
PF00082(Peptidase_S8) | 5 | ALA A 200ILE A 198ILE A 226VAL A 230ILE A 118 | None | 1.14A | 1xozA-4h6wA:undetectable | 1xozA-4h6wA:25.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4htz | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 5 | TYR A 655ILE A 822PHE A 830ILE A 855GLN A 859 | None | 0.73A | 1xozA-4htzA:43.9 | 1xozA-4htzA:34.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4htz | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 5 | TYR A 655PHE A 830ILE A 855GLN A 859PHE A 862 | None | 0.40A | 1xozA-4htzA:43.9 | 1xozA-4htzA:34.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwi | HEAT SHOCK COGNATE71 KDA PROTEIN (Homo sapiens) |
PF00012(HSP70) | 5 | ILE A 334ILE A 209VAL A 207PHE A 205LEU A 200 | None | 1.11A | 1xozA-4hwiA:undetectable | 1xozA-4hwiA:22.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4i15 | CLASS 1PHOSPHODIESTERASEPDEB1 (Trypanosomabrucei) |
PF00233(PDEase_I) | 5 | TYR A 668VAL A 840PHE A 844GLN A 874PHE A 877 | None | 0.61A | 1xozA-4i15A:39.5 | 1xozA-4i15A:30.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6f | SERINE/THREONINE-PROTEIN KINASE PLK2 (Homo sapiens) |
PF00069(Pkinase) | 5 | ALA A 307ILE A 311VAL A 182LEU A 208ILE A 189 | None | 0.93A | 1xozA-4i6fA:undetectable | 1xozA-4i6fA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcl | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Paenibacillusmacerans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 5 | ALA A 645GLN A 587VAL A 590PHE A 592LEU A 607 | None | 1.04A | 1xozA-4jclA:undetectable | 1xozA-4jclA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jmk | DUAL SPECIFICITYPROTEIN PHOSPHATASE8 (Homo sapiens) |
PF00782(DSPc) | 5 | ALA A 248ILE A 250PHE A 289LEU A 221ILE A 258 | SO4 A 501 (-3.8A)SO4 A 501 (-4.6A)NoneNoneNone | 1.06A | 1xozA-4jmkA:undetectable | 1xozA-4jmkA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5o | POLYMERASE PA (Influenza Avirus) |
PF00603(Flu_PA) | 5 | ALA A 17ILE A 13ILE A 38LEU A 109PHE A 46 | NoneNoneX48 A 306 ( 4.9A)NoneNone | 1.00A | 1xozA-4m5oA:undetectable | 1xozA-4m5oA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nfz | POLYMERASE PA (Influenza Avirus) |
PF00603(Flu_PA) | 5 | ALA A 17ILE A 13ILE A 38LEU A 109PHE A 46 | None | 0.97A | 1xozA-4nfzA:undetectable | 1xozA-4nfzA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4onr | DECORIN-BINDINGPROTEIN DBPA (Borreliellaburgdorferi) |
PF02352(Decorin_bind) | 5 | ILE A 96ILE A 156VAL A 138LEU A 126PHE A 92 | None | 1.10A | 1xozA-4onrA:undetectable | 1xozA-4onrA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pb0 | AB53 HEAVY CHAINAB53 LIGHT CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | ILE H 89PHE L 98LEU L 36ILE L 85GLN L 38 | None | 1.08A | 1xozA-4pb0H:undetectable | 1xozA-4pb0H:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ru5 | TAILSPIKE GP27 (Pseudomonasphage phi297) |
no annotation | 5 | ALA A 430ILE A 460ILE A 415VAL A 425ILE A 481 | None | 1.14A | 1xozA-4ru5A:undetectable | 1xozA-4ru5A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u1r | ATP-DEPENDENT6-PHOSPHOFRUCTOKINASE, PLATELET TYPE (Homo sapiens) |
PF00365(PFK) | 5 | ALA A 190ILE A 194GLN A 309ILE A 174LEU A 239 | None | 0.96A | 1xozA-4u1rA:undetectable | 1xozA-4u1rA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bqm | SOMATOLIBERIN,BOTULINUM NEUROTOXIN TYPED (Clostridiumbotulinum;Homo sapiens) |
PF07952(Toxin_trans) | 5 | ALA B 799ILE B 800ILE B 640PHE B 643PHE B 671 | None | 0.89A | 1xozA-5bqmB:undetectable | 1xozA-5bqmB:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6n | ACYL-COA SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00501(AMP-binding) | 5 | GLN A 185ILE A 199PHE A 95LEU A 91ILE A 82 | None | 0.98A | 1xozA-5d6nA:undetectable | 1xozA-5d6nA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dtu | PRP28 (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | TYR A 488ALA A 329ILE A 307ILE A 302ILE A 271 | None | 1.14A | 1xozA-5dtuA:undetectable | 1xozA-5dtuA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eor | ANTI VACCINIA VIRUSA27 ANTIBODY 8E3HEAVY CHAINANTI VACCINIA VIRUSA27 ANTIBODY 8E3LIGHT CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | ALA H 92ILE H 93PHE L 107ILE L 90GLN L 39 | None | 1.08A | 1xozA-5eorH:undetectable | 1xozA-5eorH:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey9 | LONG-CHAIN-FATTY-ACID--AMP LIGASE FADD32 (Mycobacteriummarinum) |
PF00501(AMP-binding) | 5 | GLN A 184ILE A 198PHE A 95LEU A 91ILE A 82 | None | 1.02A | 1xozA-5ey9A:undetectable | 1xozA-5ey9A:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT THETA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 5 | ILE q 318VAL q 305LEU q 344ILE q 284MET q 287 | None | 1.00A | 1xozA-5gw5q:undetectable | 1xozA-5gw5q:21.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5h2r | PHOSPHODIESTERASE (Trypanosomabrucei) |
no annotation | 5 | TYR A 668VAL A 841PHE A 845GLN A 875PHE A 878 | LLN A1003 ( 4.8A)LLN A1003 (-4.6A)LLN A1003 (-4.6A)LLN A1003 (-3.0A)LLN A1003 (-3.8A) | 0.67A | 1xozA-5h2rA:40.5 | 1xozA-5h2rA:32.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j9h | ENVELOPMENTPOLYPROTEIN (Puumalaorthohantavirus) |
PF01561(Hanta_G2) | 5 | ILE A 943VAL A 938PHE A 936ILE A 722PHE A 804 | None | 1.14A | 1xozA-5j9hA:undetectable | 1xozA-5j9hA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH DEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2,NADHDEHYDROGENASE[UBIQUINONE] 1SUBUNIT C2NADH-UBIQUINONEOXIDOREDUCTASE CHAIN2 (Bos taurus) |
PF00346(Complex1_49kDa)PF00361(Proton_antipo_M)PF06444(NADH_dehy_S2_C) | 5 | ALA d 47ILE d 48ILE N 239VAL N 242MET N 215 | None | 1.08A | 1xozA-5lc5d:undetectable | 1xozA-5lc5d:9.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m49 | AMINOTRANSFERASECLASS-III (Rhizobiumfreirei) |
PF00202(Aminotran_3) | 5 | ALA A 280ILE A 284VAL A 236PHE A 203ILE A 233 | None | 0.96A | 1xozA-5m49A:undetectable | 1xozA-5m49A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0s | GLUCOSYLCERAMIDASE (Thermoanaerobacteriumxylanolyticum) |
PF04685(DUF608)PF12215(Glyco_hydr_116N)PF17168(DUF5127) | 5 | ILE A 211ILE A 332VAL A 272LEU A 376PHE A 336 | None | 1.12A | 1xozA-5o0sA:undetectable | 1xozA-5o0sA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v41 | POLYKETIDE SYNTHASEPKS13 (TERMINATIONPOLYKETIDE SYNTHASE) (Mycobacteriumtuberculosis) |
PF00975(Thioesterase) | 5 | ALA A1702ILE A1703ILE A1707VAL A1711LEU A1491 | None | 1.11A | 1xozA-5v41A:undetectable | 1xozA-5v41A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5veh | KYNURENINEAMINOTRANSFERASE (Aedes aegypti) |
no annotation | 5 | ALA A 267ILE A 250VAL A 219ILE A 237MET A 243 | None | 1.02A | 1xozA-5vehA:undetectable | 1xozA-5vehA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yfp | EXOCYST COMPLEXCOMPONENT EXO84EXOCYST COMPLEXCOMPONENT SEC5 (Saccharomycescerevisiae) |
no annotation | 5 | ALA B 968VAL H 691LEU H 633ILE H 668PHE H 675 | None | 1.13A | 1xozA-5yfpB:undetectable | 1xozA-5yfpB:11.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysq | TM0415 (Thermotogamaritima) |
no annotation | 5 | ALA A 31ILE A 32VAL A 65PHE A 67PHE A 57 | None | 0.92A | 1xozA-5ysqA:undetectable | 1xozA-5ysqA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bxn | DIPHTHAMIDEBIOSYNTHESIS ENZYMEDPH2 (CandidatusMethanoperedensnitroreducens) |
no annotation | 5 | ALA A 35ILE A 38ILE A 52VAL A 50ILE A 73 | None | 1.07A | 1xozA-6bxnA:undetectable | 1xozA-6bxnA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d35 | SMOOTHENED,SOLUBLECYTOCHROMEB562,SMOOTHENED (Escherichiacoli;Xenopus laevis) |
no annotation | 5 | ALA A 468ILE A 469GLN A 165LEU A 46ILE A 50 | None | 1.04A | 1xozA-6d35A:undetectable | 1xozA-6d35A:11.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ejj | WLAC PROTEIN (Campylobacterjejuni) |
no annotation | 5 | ALA A 221ILE A 220ILE A 189LEU A 313MET A 200 | UDP A 401 ( 4.0A)NoneNoneNoneNone | 0.99A | 1xozA-6ejjA:undetectable | 1xozA-6ejjA:11.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkh | ATP SYNTHASE SUBUNITALPHA, CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 5 | ALA C 113ILE C 109ILE C 98PHE C 250ILE C 259 | None | 0.99A | 1xozA-6fkhC:undetectable | 1xozA-6fkhC:10.67 |