SIMILAR PATTERNS OF AMINO ACIDS FOR 1XOQ_B_ROFB501_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bdg | HEXOKINASE (Schistosomamansoni) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | MET A 43ASN A 235GLN A 291 | NoneGLC A 501 (-3.8A)GLC A 501 ( 4.2A) | 1.03A | 1xoqB-1bdgA:undetectable | 1xoqB-1bdgA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1og6 | HYPOTHETICALOXIDOREDUCTASE YDHF (Escherichiacoli) |
PF00248(Aldo_ket_red) | 3 | MET A 134ASN A 179GLN A 198 | None | 0.95A | 1xoqB-1og6A:undetectable | 1xoqB-1og6A:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rfv | PYRIDOXAL KINASE (Ovis aries) |
PF08543(Phos_pyr_kin) | 3 | MET A 221ASN A 251GLN A 205 | None | 0.94A | 1xoqB-1rfvA:undetectable | 1xoqB-1rfvA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tjy | SUGAR TRANSPORTPROTEIN (Salmonellaenterica) |
PF13407(Peripla_BP_4) | 3 | MET A 139ASN A 129GLN A 271 | None | 0.88A | 1xoqB-1tjyA:undetectable | 1xoqB-1tjyA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uc4 | DIOL DEHYDRASE ALPHASUBUNIT (Klebsiellaoxytoca) |
PF02286(Dehydratase_LU) | 3 | MET A 129ASN A 334GLN A 140 | None | 0.90A | 1xoqB-1uc4A:undetectable | 1xoqB-1uc4A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uli | BIPHENYL DIOXYGENASELARGE SUBUNITBIPHENYL DIOXYGENASESMALL SUBUNIT (Rhodococcusjostii;Rhodococcusjostii) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A)PF00866(Ring_hydroxyl_B) | 3 | MET A 82ASN A 112GLN B 70 | None | 1.01A | 1xoqB-1uliA:undetectable | 1xoqB-1uliA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6c | ALKALINE SERINEPROTEASE (Pseudoalteromonassp. AS-11) |
PF00082(Peptidase_S8)PF02225(PA) | 3 | MET A 370ASN A 235GLN A 285 | None | 1.05A | 1xoqB-1v6cA:undetectable | 1xoqB-1v6cA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve1 | O-ACETYLSERINESULFHYDRYLASE (Thermusthermophilus) |
PF00291(PALP) | 3 | MET A 96ASN A 72GLN A 141 | NonePLP A 413 (-3.6A)None | 0.73A | 1xoqB-1ve1A:undetectable | 1xoqB-1ve1A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5y | YKUV PROTEIN (Bacillussubtilis) |
PF00578(AhpC-TSA) | 3 | MET A 133ASN A 52GLN A 92 | None | 0.89A | 1xoqB-2b5yA:undetectable | 1xoqB-2b5yA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cqg | TAR DNA-BINDINGPROTEIN-43 (Homo sapiens) |
PF00076(RRM_1) | 3 | MET A 162ASN A 179GLN A 182 | None | 1.01A | 1xoqB-2cqgA:undetectable | 1xoqB-2cqgA:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e28 | PYRUVATE KINASE (Geobacillusstearothermophilus) |
PF00224(PK)PF00391(PEP-utilizers)PF02887(PK_C) | 3 | MET A 329ASN A 301GLN A 261 | None | 1.05A | 1xoqB-2e28A:undetectable | 1xoqB-2e28A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi8 | SULFATASE-MODIFYINGFACTOR 1 (Homo sapiens) |
PF03781(FGE-sulfatase) | 3 | MET X 161ASN X 259GLN X 262 | None CA X1017 (-3.3A) CA X1017 (-4.1A) | 0.93A | 1xoqB-2hi8X:undetectable | 1xoqB-2hi8X:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jep | XYLOGLUCANASE (Paenibacilluspabuli) |
PF00150(Cellulase) | 3 | MET A 180ASN A 146GLN A 150 | None | 1.05A | 1xoqB-2jepA:undetectable | 1xoqB-2jepA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nzt | HEXOKINASE-2 (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | MET A 491ASN A 683GLN A 739 | NoneGLC A1003 (-3.6A)GLC A1003 (-4.3A) | 0.82A | 1xoqB-2nztA:undetectable | 1xoqB-2nztA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qjp | CYTOCHROME B (Rhodobactersphaeroides) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 3 | MET A 84ASN A 99GLN A 58 | NoneNoneHEM A 502 (-4.2A) | 1.03A | 1xoqB-2qjpA:undetectable | 1xoqB-2qjpA:21.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qyk | CYCLIC AMP-SPECIFICPHOSPHODIESTERASEHSPDE4A10 (Homo sapiens) |
PF00233(PDEase_I) | 3 | MET A 485ASN A 533GLN A 581 | NoneNPV A 3 (-4.4A)NPV A 3 (-3.1A) | 0.32A | 1xoqB-2qykA:51.9 | 1xoqB-2qykA:82.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2r8q | CLASS IPHOSPHODIESTERASEPDEB1 (Leishmaniamajor) |
PF00233(PDEase_I) | 3 | MET A 797ASN A 838GLN A 887 | NoneIBM A 3 (-4.5A)IBM A 3 (-3.3A) | 0.58A | 1xoqB-2r8qA:39.4 | 1xoqB-2r8qA:30.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vzn | VENOM ALLERGEN 3 (Solenopsisinvicta) |
PF00188(CAP) | 3 | MET A 131ASN A 35GLN A 90 | None | 0.81A | 1xoqB-2vznA:undetectable | 1xoqB-2vznA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xa7 | AP-2 COMPLEX SUBUNITBETA (Homo sapiens) |
PF01602(Adaptin_N) | 3 | MET B 110ASN B 89GLN B 59 | None | 1.00A | 1xoqB-2xa7B:undetectable | 1xoqB-2xa7B:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yiu | CYTOCHROME B (Paracoccusdenitrificans) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 3 | MET A 84ASN A 99GLN A 58 | NoneNoneHEM A 500 (-4.4A) | 0.95A | 1xoqB-2yiuA:undetectable | 1xoqB-2yiuA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwu | OUTER MEMBRANE USHERPROTEIN FIMD,N-TERMINAL DOMAIN (Escherichiacoli) |
PF13954(PapC_N) | 3 | MET D 44ASN D 122GLN D 117 | None | 0.92A | 1xoqB-3bwuD:undetectable | 1xoqB-3bwuD:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE ALPHA SUBUNIT (Methanosarcinabarkeri) |
PF03063(Prismane) | 3 | MET A 168ASN A 251GLN A 322 | None | 0.82A | 1xoqB-3cf4A:undetectable | 1xoqB-3cf4A:16.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ecn | HIGH AFFINITYCAMP-SPECIFIC ANDIBMX-INSENSITIVE3',5'-CYCLICPHOSPHODIESTERASE 8A (Homo sapiens) |
PF00233(PDEase_I) | 3 | MET A 670ASN A 729GLN A 778 | IBM A 3 (-4.5A)NoneIBM A 3 (-3.4A) | 0.34A | 1xoqB-3ecnA:45.0 | 1xoqB-3ecnA:33.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eoe | PYRUVATE KINASE (Toxoplasmagondii) |
PF00224(PK)PF02887(PK_C) | 3 | MET A 363ASN A 335GLN A 295 | None | 1.03A | 1xoqB-3eoeA:undetectable | 1xoqB-3eoeA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fhx | PYRIDOXAL KINASE (Homo sapiens) |
PF08543(Phos_pyr_kin) | 3 | MET A 221ASN A 251GLN A 205 | None | 0.97A | 1xoqB-3fhxA:undetectable | 1xoqB-3fhxA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fy6 | INTEGRON CASSETTEPROTEIN (Vibrio cholerae) |
no annotation | 3 | MET A 28ASN A 71GLN A 55 | None | 0.91A | 1xoqB-3fy6A:undetectable | 1xoqB-3fy6A:17.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g4g | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4D (Homo sapiens) |
PF00233(PDEase_I) | 3 | MET A 439ASN A 487GLN A 535 | D71 A 901 ( 4.0A)D71 A 901 (-4.5A)D71 A 901 (-3.1A) | 0.58A | 1xoqB-3g4gA:52.7 | 1xoqB-3g4gA:81.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1v | GLUCOKINASE (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | MET X 37ASN X 231GLN X 287 | NoneGLC X 500 (-3.8A)GLC X 500 (-4.2A) | 0.90A | 1xoqB-3h1vX:undetectable | 1xoqB-3h1vX:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhs | PHENOLOXIDASESUBUNIT 2 (Manduca sexta) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 3 | MET A 673ASN A 663GLN A 527 | None | 1.06A | 1xoqB-3hhsA:undetectable | 1xoqB-3hhsA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkz | DNA-DIRECTED RNAPOLYMERASE SUBUNITA'DNA-DIRECTED RNAPOLYMERASE SUBUNIT B (Sulfolobussolfataricus;Sulfolobussolfataricus) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4)PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 3 | MET A 646ASN A 739GLN B 662 | None | 1.05A | 1xoqB-3hkzA:undetectable | 1xoqB-3hkzA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hm8 | HEXOKINASE-3 (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | MET A 504ASN A 689GLN A 745 | NoneGLC A1001 (-3.8A)GLC A1001 (-3.8A) | 0.93A | 1xoqB-3hm8A:undetectable | 1xoqB-3hm8A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju7 | PUTATIVEPLP-DEPENDENTAMINOTRANSFERASE (Bacillus cereus) |
PF01041(DegT_DnrJ_EryC1) | 3 | MET A 246ASN A 51GLN A 176 | None | 1.00A | 1xoqB-3ju7A:undetectable | 1xoqB-3ju7A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kv0 | HET-C2 (Podosporaanserina) |
PF08718(GLTP) | 3 | MET A 51ASN A 124GLN A 180 | None | 1.06A | 1xoqB-3kv0A:undetectable | 1xoqB-3kv0A:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kwp | PREDICTEDMETHYLTRANSFERASE (Lactobacillusbrevis) |
PF00590(TP_methylase) | 3 | MET A 28ASN A 49GLN A 63 | None | 1.04A | 1xoqB-3kwpA:undetectable | 1xoqB-3kwpA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lw2 | PLASMINOGENACTIVATOR INHIBITOR1 (Mus musculus) |
PF00079(Serpin) | 3 | MET A 62ASN A 167GLN A 322 | None | 1.02A | 1xoqB-3lw2A:undetectable | 1xoqB-3lw2A:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ml0 | PENICILLIN GACYLASE, BETASUBUNIT (Alcaligenesfaecalis) |
PF01804(Penicil_amidase) | 3 | MET B 320ASN B 335GLN B 331 | None | 0.91A | 1xoqB-3ml0B:undetectable | 1xoqB-3ml0B:20.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n3z | HIGH AFFINITYCGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 9A (Homo sapiens) |
PF00233(PDEase_I) | 3 | MET A 365ASN A 405GLN A 453 | NoneIBM A 1 (-3.5A)IBM A 1 (-3.5A) | 0.88A | 1xoqB-3n3zA:41.3 | 1xoqB-3n3zA:30.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o1h | PERIPLASMIC PROTEINTORT (Vibrioparahaemolyticus) |
PF00532(Peripla_BP_1) | 3 | MET B 52ASN B 120GLN B 77 | NoneTMO B 1 ( 4.5A)None | 0.96A | 1xoqB-3o1hB:undetectable | 1xoqB-3o1hB:26.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3o57 | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4B (Homo sapiens) |
PF00233(PDEase_I) | 3 | MET A 347ASN A 395GLN A 443 | ZG2 A 506 (-3.9A)ZG2 A 506 (-4.3A)ZG2 A 506 (-3.3A) | 0.29A | 1xoqB-3o57A:51.8 | 1xoqB-3o57A:82.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ono | RIBOSE/GALACTOSEISOMERASE (Vibrioparahaemolyticus) |
PF02502(LacAB_rpiB)PF12408(DUF3666) | 3 | MET A 1ASN A 106GLN A 103 | None | 0.98A | 1xoqB-3onoA:undetectable | 1xoqB-3onoA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9o | EXOTOXIN A (Vibrio cholerae) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 3 | MET A 46ASN A 164GLN A 26 | None | 1.04A | 1xoqB-3q9oA:undetectable | 1xoqB-3q9oA:21.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3sl5 | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4D (Homo sapiens) |
PF00233(PDEase_I) | 3 | MET A 273ASN A 321GLN A 369 | MET A 273 (-0.0A)ASN A 321 (-0.6A)GLN A 369 (-0.6A) | 0.31A | 1xoqB-3sl5A:53.4 | 1xoqB-3sl5A:94.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3snx | PUTATIVE SUSD-LIKECARBOHYDRATE BINDINGPROTEIN (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 3 | MET A 356ASN A 222GLN A 204 | None | 0.89A | 1xoqB-3snxA:undetectable | 1xoqB-3snxA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swh | PROTEIN UNC-13HOMOLOG A (Rattusnorvegicus) |
PF10540(Membr_traf_MHD) | 3 | MET A1231ASN A1210GLN A1208 | None | 0.94A | 1xoqB-3swhA:undetectable | 1xoqB-3swhA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t95 | AUTOINDUCER2-BINDING PROTEINLSRB (Yersinia pestis) |
PF13407(Peripla_BP_4) | 3 | MET A 138ASN A 128GLN A 270 | None | 0.96A | 1xoqB-3t95A:undetectable | 1xoqB-3t95A:25.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr9 | DIHYDROPTEROATESYNTHASE (Coxiellaburnetii) |
PF00809(Pterin_bind) | 3 | MET A 240ASN A 206GLN A 132 | PT1 A1001 ( 4.2A)NonePT1 A1001 ( 3.4A) | 1.01A | 1xoqB-3tr9A:undetectable | 1xoqB-3tr9A:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3trj | PHOSPHOHEPTOSEISOMERASE (Francisellatularensis) |
PF13580(SIS_2) | 3 | MET A 155ASN A 126GLN A 99 | None | 0.98A | 1xoqB-3trjA:undetectable | 1xoqB-3trjA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uug | MULTIPLESUGAR-BINDINGPERIPLASMIC RECEPTORCHVE (Agrobacteriumfabrum) |
PF13407(Peripla_BP_4) | 3 | MET A 175ASN A 108GLN A 241 | NoneNoneBDP A 331 ( 4.1A) | 1.04A | 1xoqB-3uugA:undetectable | 1xoqB-3uugA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8b | PUTATIVEDEHYDROGENASE,POSSIBLY3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 3 | MET A 69ASN A 89GLN A 164 | None | 0.98A | 1xoqB-3v8bA:undetectable | 1xoqB-3v8bA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8d | CHOLESTEROL7-ALPHA-MONOOXYGENASE (Homo sapiens) |
PF00067(p450) | 3 | MET A 435ASN A 81GLN A 60 | NoneSO4 A 603 (-3.7A)None | 0.92A | 1xoqB-3v8dA:undetectable | 1xoqB-3v8dA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w0l | GLUCOKINASE (Xenopus laevis) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | MET A 30ASN A 224GLN A 280 | None | 0.89A | 1xoqB-3w0lA:undetectable | 1xoqB-3w0lA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zei | O-ACETYLSERINESULFHYDRYLASE (Mycobacteriumtuberculosis) |
PF00291(PALP) | 3 | MET A 98ASN A 74GLN A 144 | NonePLP A1301 (-3.8A)AWH A1302 (-3.3A) | 0.90A | 1xoqB-3zeiA:undetectable | 1xoqB-3zeiA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aec | CYSTEINE SYNTHASE,MITOCHONDRIAL (Arabidopsisthaliana) |
PF00291(PALP) | 3 | MET A 209ASN A 185GLN A 255 | NonePLP A 500 (-3.8A)None | 0.82A | 1xoqB-4aecA:undetectable | 1xoqB-4aecA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4af0 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Cryptococcusneoformans) |
PF00478(IMPDH)PF00571(CBS) | 3 | MET B 351ASN B 317GLN B 323 | MOA B1526 ( 4.7A)MOA B1526 ( 3.6A)None | 1.01A | 1xoqB-4af0B:undetectable | 1xoqB-4af0B:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 3 | MET A1486ASN A1412GLN A1469 | None | 0.92A | 1xoqB-4bedA:undetectable | 1xoqB-4bedA:12.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1t | SUGAR TRANSPORTERSOLUTE-BINDINGPROTEIN (Bifidobacteriumanimalis) |
PF01547(SBP_bac_1) | 3 | MET A 274ASN A 39GLN A 71 | NoneXYP A1003 (-3.3A)None | 1.03A | 1xoqB-4c1tA:undetectable | 1xoqB-4c1tA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cyf | PANTETHEINASE (Homo sapiens) |
PF00795(CN_hydrolase) | 3 | MET A 239ASN A 86GLN A 187 | None | 0.82A | 1xoqB-4cyfA:undetectable | 1xoqB-4cyfA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dpk | MALONYL-COA/SUCCINYL-COA REDUCTASE (Sulfurisphaeratokodaii) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 3 | MET A 26ASN A 109GLN A 156 | None | 1.06A | 1xoqB-4dpkA:undetectable | 1xoqB-4dpkA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dwe | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF15421(Polysacc_deac_3) | 3 | MET A 420ASN A 447GLN A 155 | None | 1.03A | 1xoqB-4dweA:undetectable | 1xoqB-4dweA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e5v | PUTATIVE THUA-LIKEPROTEIN (Parabacteroidesmerdae) |
PF06283(ThuA) | 3 | MET A 260ASN A 37GLN A 42 | None | 1.03A | 1xoqB-4e5vA:undetectable | 1xoqB-4e5vA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f9o | HEXOKINASE-1 (Homo sapiens) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | MET A 491ASN A 683GLN A 739 | NoneBGC A1003 (-3.9A)BGC A1003 (-4.4A) | 0.78A | 1xoqB-4f9oA:undetectable | 1xoqB-4f9oA:16.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4i15 | CLASS 1PHOSPHODIESTERASEPDEB1 (Trypanosomabrucei) |
PF00233(PDEase_I) | 3 | MET A 785ASN A 825GLN A 874 | None | 0.69A | 1xoqB-4i15A:38.7 | 1xoqB-4i15A:32.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jzn | ANTI-HCV E2 FABHC84-1 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | MET A 81ASN A 85GLN A 65 | None | 1.05A | 1xoqB-4jznA:undetectable | 1xoqB-4jznA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kds | PLASMINOGENACTIVATOR INHIBITOR1 (Oncorhynchusmykiss) |
PF00079(Serpin) | 3 | MET A 287ASN A 28GLN A 316 | None | 0.92A | 1xoqB-4kdsA:undetectable | 1xoqB-4kdsA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l5n | URACIL-DNAGLYCOSYLASEEARLY PROTEIN GP1B (Humanalphaherpesvirus1;Bacillus virusphi29) |
PF03167(UDG)no annotation | 3 | MET C 14ASN C 42GLN A 95 | NoneACT A 301 ( 4.9A)None | 1.04A | 1xoqB-4l5nC:undetectable | 1xoqB-4l5nC:10.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgl | GLYCINEDEHYDROGENASE[DECARBOXYLATING] (Synechocystissp. PCC 6803) |
PF02347(GDC-P) | 3 | MET A 177ASN A 210GLN A 599 | None | 1.05A | 1xoqB-4lglA:undetectable | 1xoqB-4lglA:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4li3 | CYSTEINE SYNTHASE (Haemophilusinfluenzae) |
PF00291(PALP) | 3 | MET X 96ASN X 72GLN X 143 | NoneLLP X 42 ( 3.8A)LLP X 42 ( 4.9A) | 0.92A | 1xoqB-4li3X:undetectable | 1xoqB-4li3X:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mmo | SSO-CP2METALLO-CARBOXYPETIDASE (Sulfolobussolfataricus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 3 | MET A 359ASN A 70GLN A 381 | None | 0.99A | 1xoqB-4mmoA:undetectable | 1xoqB-4mmoA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnp | N-ACETYLNEURAMINATE-BINDING PROTEIN (Fusobacteriumnucleatum) |
PF03480(DctP) | 3 | MET A 54ASN A 44GLN A 16 | None | 1.04A | 1xoqB-4mnpA:undetectable | 1xoqB-4mnpA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qs9 | HEXOKINASE-1 (Arabidopsisthaliana) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 3 | MET A 62ASN A 256GLN A 312 | NoneBGC A 501 (-3.7A)BGC A 501 ( 4.4A) | 0.77A | 1xoqB-4qs9A:undetectable | 1xoqB-4qs9A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9o | PUTATIVE ALDO/KETOREDUCTASE (Salmonellaenterica) |
PF00248(Aldo_ket_red) | 3 | MET A 134ASN A 179GLN A 198 | None | 0.86A | 1xoqB-4r9oA:undetectable | 1xoqB-4r9oA:23.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4to8 | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE,CLASS II (Staphylococcusaureus) |
PF01116(F_bP_aldolase) | 3 | MET A 57ASN A 233GLN A 22 | NoneFLC A 302 (-4.2A)None | 1.06A | 1xoqB-4to8A:undetectable | 1xoqB-4to8A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tv7 | HTH-TYPETRANSCRIPTIONALREGULATORY PROTEINGABR (Bacillussubtilis) |
PF00155(Aminotran_1_2)PF00392(GntR) | 3 | MET A 200ASN A 214GLN A 186 | None | 1.03A | 1xoqB-4tv7A:undetectable | 1xoqB-4tv7A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w66 | GLUTATHIONES-TRANSFERASE DOMAINPROTEIN (Haliangiumochraceum) |
PF14497(GST_C_3) | 3 | MET A 222ASN A 118GLN A 130 | None | 1.01A | 1xoqB-4w66A:undetectable | 1xoqB-4w66A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wvm | STONUSTOXIN SUBUNITBETA (Synanceiahorrida) |
PF00622(SPRY)PF13765(PRY) | 3 | MET B 69ASN B 95GLN B 96 | None | 1.05A | 1xoqB-4wvmB:undetectable | 1xoqB-4wvmB:17.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4wzi | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4B (Homo sapiens) |
PF00233(PDEase_I) | 3 | MET A 519ASN A 567GLN A 615 | None | 0.43A | 1xoqB-4wziA:52.6 | 1xoqB-4wziA:48.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xfe | TRAP DICARBOXYLATETRANSPORTER SUBUNITDCTP (Pseudomonasputida) |
PF03480(DctP) | 3 | MET A 265ASN A 326GLN A 330 | None | 0.78A | 1xoqB-4xfeA:undetectable | 1xoqB-4xfeA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhp | PARM HYBRID FUSIONPROTEIN (Bacillusthuringiensis) |
no annotation | 3 | MET A 134ASN A 194GLN A 415 | None | 1.06A | 1xoqB-4xhpA:undetectable | 1xoqB-4xhpA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg8 | ENDOGLUCANASE (Perinereisbrevicirris) |
PF00759(Glyco_hydro_9) | 3 | MET A 237ASN A 272GLN A 246 | None | 0.99A | 1xoqB-4zg8A:undetectable | 1xoqB-4zg8A:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dvj | BINDING PROTEINCOMPONENT OF ABCSUGAR TRANSPORTER (Pseudomonasputida) |
PF01547(SBP_bac_1) | 3 | MET A 129ASN A 141GLN A 332 | None | 1.01A | 1xoqB-5dvjA:undetectable | 1xoqB-5dvjA:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epg | ALDEHYDE OXIDASE (Homo sapiens) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 3 | MET A 753ASN A 436GLN A1235 | FES A3001 (-4.9A)NoneNone | 1.03A | 1xoqB-5epgA:undetectable | 1xoqB-5epgA:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fl7 | ATP SYNTHASE SUBUNITALPHA (Yarrowialipolytica) |
PF00006(ATP-synt_ab)PF00306(ATP-synt_ab_C)PF02874(ATP-synt_ab_N) | 3 | MET A 409ASN A 211GLN A 456 | None | 1.02A | 1xoqB-5fl7A:undetectable | 1xoqB-5fl7A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | SUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | MET B 753ASN B 98GLN B 72 | None | 0.88A | 1xoqB-5fq6B:undetectable | 1xoqB-5fq6B:15.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5h2r | PHOSPHODIESTERASE (Trypanosomabrucei) |
no annotation | 3 | MET A 785ASN A 826GLN A 875 | LLN A1003 (-4.0A)LLN A1003 (-4.4A)LLN A1003 (-3.0A) | 0.40A | 1xoqB-5h2rA:39.2 | 1xoqB-5h2rA:32.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h60 | TRANSFERASE (Escherichiacoli) |
no annotation | 3 | MET A 276ASN A 256GLN A 50 | NoneNoneUDP A 401 (-4.6A) | 1.04A | 1xoqB-5h60A:undetectable | 1xoqB-5h60A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jkj | ESTERASE E22 (unculturedbacterium) |
PF00561(Abhydrolase_1) | 3 | MET A 358ASN A 320GLN A 203 | None | 0.81A | 1xoqB-5jkjA:undetectable | 1xoqB-5jkjA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l8s | AMINO ACYL PEPTIDASE (Sporosarcinapsychrophila) |
PF00326(Peptidase_S9) | 3 | MET A 341ASN A 331GLN A 327 | None | 0.93A | 1xoqB-5l8sA:undetectable | 1xoqB-5l8sA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ls6 | HISTONE-LYSINEN-METHYLTRANSFERASEEZH2,HISTONE-LYSINEN-METHYLTRANSFERASEEZH2,HISTONE-LYSINEN-METHYLTRANSFERASEEZH2POLYCOMB PROTEINSUZ12 (Homo sapiens;Homo sapiens) |
PF00856(SET)PF11616(EZH2_WD-Binding)PF09733(VEFS-Box) | 3 | MET A 439ASN C 651GLN C 685 | None | 0.98A | 1xoqB-5ls6A:undetectable | 1xoqB-5ls6A:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lun | 2-OXOGLUTARATE-DEPENDENTETHYLENE/SUCCINATE-FORMING ENZYME (Pseudomonassavastanoi) |
PF03171(2OG-FeII_Oxy)PF14226(DIOX_N) | 3 | MET A 313ASN A 218GLN A 256 | ARG A 403 ( 4.6A)NoneNone | 0.97A | 1xoqB-5lunA:undetectable | 1xoqB-5lunA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m28 | MALE1 (Lactobacilluscasei) |
PF13416(SBP_bac_8) | 3 | MET A 120ASN A 105GLN A 300 | None | 0.89A | 1xoqB-5m28A:undetectable | 1xoqB-5m28A:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ncs | SERPIN (Tannerellaforsythia) |
PF00079(Serpin) | 3 | MET A 231ASN A 378GLN A 247 | None | 0.88A | 1xoqB-5ncsA:undetectable | 1xoqB-5ncsA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ohj | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4B (Homo sapiens) |
no annotation | 3 | MET A 519ASN A 567GLN A 615 | 9VE A 801 (-3.8A)9VE A 801 (-4.1A)9VE A 801 (-3.2A) | 0.31A | 1xoqB-5ohjA:51.9 | 1xoqB-5ohjA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wh6 | CAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 4D (Homo sapiens) |
no annotation | 3 | MET A 273ASN A 321GLN A 369 | AKJ A 601 ( 3.9A)AKJ A 601 (-4.3A)AKJ A 601 (-3.0A) | 0.11A | 1xoqB-5wh6A:55.1 | 1xoqB-5wh6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xa2 | CYSTEINE SYNTHASE (Planctopiruslimnophila) |
PF00291(PALP) | 3 | MET A 98ASN A 74GLN A 143 | NoneLLP A 44 ( 3.8A)LLP A 44 ( 4.8A) | 0.71A | 1xoqB-5xa2A:undetectable | 1xoqB-5xa2A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y7f | UGGT (Thermomycesdupontii) |
PF01501(Glyco_transf_8) | 3 | MET A1321ASN A1431GLN A1445 | None | 0.98A | 1xoqB-5y7fA:undetectable | 1xoqB-5y7fA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ygu | DIAMINOPIMELATEEPIMERASE (Escherichiacoli) |
no annotation | 3 | MET A 118ASN A 11GLN A 44 | NoneIOD A 308 (-4.5A)None | 0.71A | 1xoqB-5yguA:undetectable | 1xoqB-5yguA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yy0 | CYTOSOLICNIFE-HYDROGENASE,ALPHA SUBUNIT (Thermococcuskodakarensis) |
no annotation | 3 | MET A 269ASN A 307GLN A 204 | None | 1.01A | 1xoqB-5yy0A:undetectable | 1xoqB-5yy0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6au1 | PUTATIVE HEMINSTORAGE PROTEIN (Bordetellabronchiseptica) |
no annotation | 3 | MET A 584ASN A 547GLN A 564 | None | 0.86A | 1xoqB-6au1A:undetectable | 1xoqB-6au1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6epd | PROTEASOME SUBUNITBETA TYPE-4 (Rattusnorvegicus) |
no annotation | 3 | MET 7 70ASN 7 90GLN 7 113 | None | 1.03A | 1xoqB-6epd7:undetectable | 1xoqB-6epd7:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fsa | - (-) |
no annotation | 3 | MET A 439ASN A 232GLN A 288 | None MG A2001 ( 4.5A)None | 1.05A | 1xoqB-6fsaA:undetectable | 1xoqB-6fsaA:undetectable |