SIMILAR PATTERNS OF AMINO ACIDS FOR 1XIU_A_9CRA201
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1air | PECTATE LYASE C (Dickeyachrysanthemi) |
PF00544(Pec_lyase_C) | 5 | ILE A 33ALA A 36ALA A 35ALA A 49VAL A 82 | None | 0.97A | 1xiuA-1airA:undetectable | 1xiuA-1airA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dqu | ISOCITRATE LYASE (Aspergillusnidulans) |
PF00463(ICL) | 5 | ILE A 166ALA A 192ALA A 191LEU A 59ALA A 56 | None | 0.99A | 1xiuA-1dquA:undetectable | 1xiuA-1dquA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dwa | MYROSINASE MA1 (Sinapis alba) |
PF00232(Glyco_hydro_1) | 5 | ALA M 34LEU M 455ALA M 456VAL M 179LEU M 124 | None | 0.98A | 1xiuA-1dwaM:undetectable | 1xiuA-1dwaM:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e19 | CARBAMATE KINASE (Pyrococcusfuriosus) |
PF00696(AA_kinase) | 6 | ILE A 37ALA A 34LEU A 97ALA A 96VAL A 5LEU A 234 | None | 0.98A | 1xiuA-1e19A:undetectable | 1xiuA-1e19A:24.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fc4 | 2-AMINO-3-KETOBUTYRATE CONENZYME ALIGASE (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | ILE A 238ALA A 255ALA A 256LEU A 100ALA A 97 | None | 0.88A | 1xiuA-1fc4A:undetectable | 1xiuA-1fc4A:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n60 | CARBON MONOXIDEDEHYDROGENASE SMALLCHAIN (Oligotrophacarboxidovorans) |
PF00111(Fer2)PF01799(Fer2_2) | 5 | ILE A 149ALA A 152ALA A 153LEU A 90ALA A 89 | None | 0.93A | 1xiuA-1n60A:undetectable | 1xiuA-1n60A:19.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uhl | RETINOIC ACIDRECEPTOR RXR-BETA (Homo sapiens) |
PF00104(Hormone_recep) | 11 | CYH A 340ALA A 342ALA A 343GLN A 346PHE A 384ARG A 387LEU A 397ALA A 398VAL A 413CYH A 503LEU A 507 | NoneMEI A1001 (-3.1A)MEI A1001 (-3.3A)NoneMEI A1001 (-4.5A)MEI A1001 (-3.6A)MEI A1001 ( 4.4A)MEI A1001 (-3.4A)MEI A1001 (-4.1A)MEI A1001 (-4.0A)MEI A1001 (-4.6A) | 0.65A | 1xiuA-1uhlA:31.3 | 1xiuA-1uhlA:76.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uhl | RETINOIC ACIDRECEPTOR RXR-BETA (Homo sapiens) |
PF00104(Hormone_recep) | 11 | ILE A 339CYH A 340ALA A 342ALA A 343GLN A 346PHE A 384ARG A 387LEU A 397ALA A 398VAL A 413CYH A 503 | MEI A1001 (-3.8A)NoneMEI A1001 (-3.1A)MEI A1001 (-3.3A)NoneMEI A1001 (-4.5A)MEI A1001 (-3.6A)MEI A1001 ( 4.4A)MEI A1001 (-3.4A)MEI A1001 (-4.1A)MEI A1001 (-4.0A) | 0.60A | 1xiuA-1uhlA:31.3 | 1xiuA-1uhlA:76.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xls | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 12 | ILE A 268CYH A 269ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYH A 432LEU A 436 | 9CR A 801 (-3.9A)9CR A 801 ( 4.5A)9CR A 801 (-3.6A)9CR A 801 (-3.5A)9CR A 801 (-4.7A)9CR A 801 (-4.3A)9CR A 801 (-2.6A)9CR A 801 (-4.1A)9CR A 801 (-3.3A)9CR A 801 ( 4.3A)9CR A 801 ( 3.7A)9CR A 801 (-4.7A) | 0.37A | 1xiuA-1xlsA:31.6 | 1xiuA-1xlsA:82.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xv9 | ORPHAN NUCLEARRECEPTOR NR1I3 (Homo sapiens) |
PF00104(Hormone_recep) | 5 | ALA B 197ALA B 198LEU B 267ALA B 266LEU B 342 | None | 0.92A | 1xiuA-1xv9B:18.9 | 1xiuA-1xv9B:27.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yfm | FUMARASE (Saccharomycescerevisiae) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 5 | ILE A 391ALA A 176ALA A 177GLN A 180LEU A 70 | None | 0.98A | 1xiuA-1yfmA:undetectable | 1xiuA-1yfmA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z05 | TRANSCRIPTIONALREGULATOR, ROKFAMILY (Vibrio cholerae) |
PF00480(ROK) | 5 | ILE A 299CYH A 300ALA A 302ALA A 303LEU A 288 | None | 0.53A | 1xiuA-1z05A:undetectable | 1xiuA-1z05A:20.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1z5x | ULTRASPIRACLEPROTEIN (USP) AHOMOLOGUE OF RXR (Bemisia tabaci) |
PF00104(Hormone_recep) | 6 | ILE U 303CYH U 304ALA U 306ALA U 307LEU U 365ALA U 362 | None | 0.93A | 1xiuA-1z5xU:21.7 | 1xiuA-1z5xU:67.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z6r | MLC PROTEIN (Escherichiacoli) |
PF00480(ROK) | 5 | CYH A 301ALA A 303ALA A 304LEU A 290VAL A 271 | None | 0.88A | 1xiuA-1z6rA:undetectable | 1xiuA-1z6rA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk7 | MERCURIC REDUCTASE (Pseudomonasaeruginosa) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 6 | ALA A 452ALA A 451GLN A 453LEU A 434ALA A 435VAL A 356 | NoneNoneGOL A3003 ( 3.8A)NoneNoneNone | 1.30A | 1xiuA-1zk7A:undetectable | 1xiuA-1zk7A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpn | GLYCEROL KINASE (Thermusthermophilus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ALA A 57ALA A 58ALA A 29VAL A 163LEU A 171 | None | 0.82A | 1xiuA-2dpnA:undetectable | 1xiuA-2dpnA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fv2 | RCD1 REQUIRED FORCELLDIFFERENTIATION1HOMOLOG (Homo sapiens) |
PF04078(Rcd1) | 5 | ALA A 85GLN A 82LEU A 130ALA A 129LEU A 51 | None | 0.69A | 1xiuA-2fv2A:undetectable | 1xiuA-2fv2A:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g28 | PYRUVATEDEHYDROGENASE E1COMPONENT (Escherichiacoli) |
PF00456(Transketolase_N) | 5 | CYH A 611ALA A 613ALA A 614LEU A 196LEU A 623 | None | 0.64A | 1xiuA-2g28A:undetectable | 1xiuA-2g28A:15.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gl8 | RETINOIC ACIDRECEPTOR RXR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | PHE A 92ARG A 95LEU A 105ALA A 106VAL A 121CYH A 211 | None | 0.81A | 1xiuA-2gl8A:28.0 | 1xiuA-2gl8A:78.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iec | UNCHARACTERIZEDPROTEIN CONSERVED INARCHAEA (Methanopyruskandleri) |
PF04038(DHNA) | 5 | ILE A 49ALA A 52ALA A 53GLN A 56VAL A 66 | None | 1.00A | 1xiuA-2iecA:undetectable | 1xiuA-2iecA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jsw | TALIN-1 (Mus musculus) |
PF01608(I_LWEQ) | 5 | ILE A2345ALA A2348ALA A2349ALA A2466LEU A2326 | None | 1.01A | 1xiuA-2jswA:undetectable | 1xiuA-2jswA:23.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nxx | ULTRASPIRACLE (USP,NR2B4) (Triboliumcastaneum) |
PF00104(Hormone_recep) | 5 | PHE A 259ARG A 262LEU A 272ALA A 273CYH A 378 | None | 0.69A | 1xiuA-2nxxA:26.2 | 1xiuA-2nxxA:67.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oi2 | MEVALONATE KINASE (Streptococcuspneumoniae) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | ILE A 79ALA A 99ALA A 98LEU A 57ALA A 60 | None | 0.96A | 1xiuA-2oi2A:undetectable | 1xiuA-2oi2A:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p6w | PUTATIVEGLYCOSYLTRANSFERASE(MANNOSYLTRANSFERASE) INVOLVED INGLYCOSYLATING THEPBCV-1 MAJOR CAPSIDPROTEIN (ParameciumbursariaChlorella virus1) |
PF05637(Glyco_transf_34) | 5 | ILE A 61ALA A 64ALA A 65LEU A 9VAL A 136 | None | 0.95A | 1xiuA-2p6wA:undetectable | 1xiuA-2p6wA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q2e | TYPE 2 DNATOPOISOMERASE 6SUBUNIT B (Methanosarcinamazei) |
PF02518(HATPase_c)PF09239(Topo-VIb_trans) | 5 | ILE B 277CYH B 278ALA B 280ALA B 281PHE B 304 | None | 0.97A | 1xiuA-2q2eB:undetectable | 1xiuA-2q2eB:17.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q60 | RETINOID X RECEPTOR (Polyandrocarpamisakiensis) |
PF00104(Hormone_recep) | 5 | PHE A 188ARG A 191ALA A 202VAL A 217CYH A 307 | None | 0.73A | 1xiuA-2q60A:27.0 | 1xiuA-2q60A:69.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q8w | POKEWEED ANTIVIRALPROTEIN (Phytolaccaacinosa) |
PF00161(RIP) | 5 | ILE A 214ALA A 217ARG A 240LEU A 222ALA A 221 | None | 0.96A | 1xiuA-2q8wA:undetectable | 1xiuA-2q8wA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qpm | CYTOKININDEHYDROGENASE 1 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 5 | ILE A 315ALA A 313LEU A 301ALA A 302VAL A 360 | None | 0.98A | 1xiuA-2qpmA:undetectable | 1xiuA-2qpmA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vml | PHYCOCYANIN ALPHACHAINPHYCOCYANIN BETACHAIN (Gloeobacterviolaceus) |
PF00502(Phycobilisome) | 5 | ALA A 40ALA A 41ALA A 150VAL B 31LEU B 24 | None | 0.85A | 1xiuA-2vmlA:undetectable | 1xiuA-2vmlA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsx | EUKARYOTICINITIATION FACTOR 4FSUBUNIT P150 (Saccharomycescerevisiae) |
PF02854(MIF4G) | 5 | ILE E 652ALA E 656LEU E 614VAL E 673LEU E 753 | None | 0.93A | 1xiuA-2vsxE:undetectable | 1xiuA-2vsxE:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | ILE A 62ALA A 66ALA A 65LEU A 84ALA A 81 | None | 1.01A | 1xiuA-2xaxA:undetectable | 1xiuA-2xaxA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zuf | ARGINYL-TRNASYNTHETASE (Pyrococcushorikoshii) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 6 | ILE A 394ALA A 397GLN A 399LEU A 410ALA A 407LEU A 322 | None | 1.27A | 1xiuA-2zufA:undetectable | 1xiuA-2zufA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afg | SUBTILISIN-LIKESERINE PROTEASE (Thermococcuskodakarensis) |
PF00082(Peptidase_S8)PF04151(PPC) | 5 | ILE A 368ALA A 415ALA A 416LEU A 388ALA A 387 | None | 0.92A | 1xiuA-3afgA:undetectable | 1xiuA-3afgA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3am6 | RHODOPSIN-2 (Acetabulariaacetabulum) |
PF01036(Bac_rhodopsin) | 5 | ILE A 44ALA A 47VAL A 95CYH A 218LEU A 219 | NoneNoneNoneNoneCLR A 401 ( 4.6A) | 0.88A | 1xiuA-3am6A:undetectable | 1xiuA-3am6A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ci0 | PSEUDOPILIN GSPK (Escherichiacoli) |
PF03934(T2SSK) | 5 | ILE K 218ALA K 221LEU K 119ALA K 118LEU K 271 | None | 1.02A | 1xiuA-3ci0K:undetectable | 1xiuA-3ci0K:24.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cir | FUMARATE REDUCTASEIRON-SULFUR SUBUNIT (Escherichiacoli) |
PF13085(Fer2_3)PF13183(Fer4_8) | 5 | CYH B 154ALA B 156ALA B 157LEU B 93ALA B 94 | SF4 B 246 (-2.2A)NoneNoneNoneNone | 1.01A | 1xiuA-3cirB:undetectable | 1xiuA-3cirB:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d0q | PROTEIN CALG3 (Micromonosporaechinospora) |
PF06722(DUF1205) | 5 | ILE A 233ALA A 236ALA A 237ALA A 334LEU A 246 | None | 0.93A | 1xiuA-3d0qA:undetectable | 1xiuA-3d0qA:21.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 12 | ILE A 268CYH A 269ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYH A 432LEU A 436 | 9CR A7223 (-3.9A)None9CR A7223 (-3.5A)9CR A7223 (-4.2A)9CR A7223 (-4.6A)9CR A7223 (-4.5A)9CR A7223 (-3.7A)9CR A7223 (-3.8A)9CR A7223 ( 4.7A)9CR A7223 ( 4.5A)9CR A7223 (-3.8A)9CR A7223 ( 4.7A) | 0.67A | 1xiuA-3dzuA:30.3 | 1xiuA-3dzuA:62.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5k | RIBOSOME-INACTIVATING PROTEINPD-L1/PD-L2 (Phytolaccadioica) |
PF00161(RIP) | 5 | ILE A 214ALA A 217ARG A 240LEU A 222ALA A 221 | None | 0.95A | 1xiuA-3h5kA:undetectable | 1xiuA-3h5kA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hve | GIGAXONIN (Homo sapiens) |
PF00651(BTB)PF07707(BACK) | 5 | ILE A 47ALA A 50ALA A 51LEU B 20ALA B 19 | None | 0.68A | 1xiuA-3hveA:undetectable | 1xiuA-3hveA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hve | GIGAXONIN (Homo sapiens) |
PF00651(BTB)PF07707(BACK) | 5 | ILE A 47ALA A 50LEU B 20ALA B 19LEU A 87 | None | 0.79A | 1xiuA-3hveA:undetectable | 1xiuA-3hveA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hve | GIGAXONIN (Homo sapiens) |
PF00651(BTB)PF07707(BACK) | 5 | ILE B 47ALA B 50ALA B 51LEU A 20ALA A 19 | None | 0.73A | 1xiuA-3hveB:undetectable | 1xiuA-3hveB:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hve | GIGAXONIN (Homo sapiens) |
PF00651(BTB)PF07707(BACK) | 5 | ILE B 47ALA B 50LEU A 20ALA A 19LEU B 87 | None | 0.95A | 1xiuA-3hveB:undetectable | 1xiuA-3hveB:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic5 | PUTATIVESACCHAROPINEDEHYDROGENASE (Ruegeriapomeroyi) |
PF03435(Sacchrp_dh_NADP) | 5 | ILE A 82ALA A 85ALA A 86LEU A 60ALA A 61 | None | 0.83A | 1xiuA-3ic5A:undetectable | 1xiuA-3ic5A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipc | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (AMINO ACID) (Agrobacteriumfabrum) |
PF13458(Peripla_BP_6) | 5 | ILE A 286ALA A 289ALA A 290LEU A 305ALA A 304 | None | 0.83A | 1xiuA-3ipcA:undetectable | 1xiuA-3ipcA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iv7 | ALCOHOLDEHYDROGENASE IV (Corynebacteriumglutamicum) |
PF00465(Fe-ADH) | 5 | ALA A 347ALA A 348LEU A 357CYH A 244LEU A 247 | None | 1.02A | 1xiuA-3iv7A:undetectable | 1xiuA-3iv7A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jru | PROBABLE CYTOSOLAMINOPEPTIDASE (Xanthomonasoryzae) |
no annotation | 5 | ALA B 139ALA B 138LEU B 3ALA B 2VAL B 21 | None | 1.00A | 1xiuA-3jruB:undetectable | 1xiuA-3jruB:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ktc | XYLOSE ISOMERASE (Pectobacteriumatrosepticum) |
PF01261(AP_endonuc_2) | 5 | ILE A 292ALA A 295LEU A 324ALA A 323VAL A 230 | None | 1.00A | 1xiuA-3ktcA:undetectable | 1xiuA-3ktcA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0m | HIT FAMILY PROTEIN (Mycolicibacteriumsmegmatis) |
PF01230(HIT) | 5 | ILE A 67ALA A 70ALA A 71LEU A 136ALA A 135 | None | 0.70A | 1xiuA-3o0mA:undetectable | 1xiuA-3o0mA:24.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o10 | SACSIN (Homo sapiens) |
PF05168(HEPN) | 5 | ALA A4487ALA A4488LEU A4451ALA A4447LEU A4519 | None | 0.92A | 1xiuA-3o10A:undetectable | 1xiuA-3o10A:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oks | 4-AMINOBUTYRATETRANSAMINASE (Mycolicibacteriumsmegmatis) |
PF00202(Aminotran_3) | 5 | ILE A 327ALA A 331ALA A 330LEU A 298ALA A 295 | None | 1.00A | 1xiuA-3oksA:undetectable | 1xiuA-3oksA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtp | ENOLASE 1 (Entamoebahistolytica) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ILE A 116CYH A 117ALA A 119ALA A 120LEU A 135 | None | 0.82A | 1xiuA-3qtpA:undetectable | 1xiuA-3qtpA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT N (Escherichiacoli) |
no annotation | 5 | ILE N 250ALA N 249LEU N 119ALA N 120LEU N 306 | None | 0.85A | 1xiuA-3rkoN:undetectable | 1xiuA-3rkoN:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1s | RESTRICTIONENDONUCLEASE BPUSI (Bacilluspumilus) |
PF02384(N6_Mtase)PF15516(BpuSI_N) | 5 | ILE A 28CYH A 29ALA A 31ALA A 32GLN A 35 | None | 0.92A | 1xiuA-3s1sA:undetectable | 1xiuA-3s1sA:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uc2 | HYPOTHETICAL PROTEINWITHIMMUNOGLOBULIN-LIKEFOLD (Pseudomonasaeruginosa) |
PF14467(DUF4426) | 5 | ILE A 59ALA A 103GLN A 104PHE A 105LEU A 88 | None | 0.96A | 1xiuA-3uc2A:undetectable | 1xiuA-3uc2A:24.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3upn | PENICILLIN-BINDINGPROTEIN A (Mycobacteriumtuberculosis) |
PF00905(Transpeptidase) | 5 | ALA A 231ALA A 232LEU A 298ALA A 297LEU A 274 | None | 0.91A | 1xiuA-3upnA:undetectable | 1xiuA-3upnA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxw | ADIPONECTIN RECEPTORPROTEIN 2 (Homo sapiens) |
PF03006(HlyIII) | 5 | ILE A 322ALA A 325ALA A 326LEU A 283ALA A 279 | None | 0.70A | 1xiuA-3wxwA:undetectable | 1xiuA-3wxwA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a7w | URIDYLATE KINASE (Helicobacterpylori) |
PF00696(AA_kinase) | 5 | ILE A 39ALA A 36LEU A 94ALA A 93VAL A 10 | None | 0.85A | 1xiuA-4a7wA:undetectable | 1xiuA-4a7wA:25.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4au0 | EXOGLUCANASE 2 (Trichodermareesei) |
PF01341(Glyco_hydro_6) | 5 | ALA A 280ALA A 279GLN A 281LEU A 336VAL A 323 | None | 0.99A | 1xiuA-4au0A:undetectable | 1xiuA-4au0A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8b | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1 (Saccharomycescerevisiae) |
PF16417(CNOT1_TTP_bind)PF16418(CNOT1_HEAT)PF16419(CNOT1_HEAT_N) | 6 | ILE A 741ALA A 744ALA A 745LEU A 714ALA A 715VAL A 728 | None | 1.14A | 1xiuA-4b8bA:undetectable | 1xiuA-4b8bA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1k | TRIOSEPHOSPHATEISOMERASE (Burkholderiathailandensis) |
PF00121(TIM) | 5 | ILE A 246CYH A 247ALA A 249ALA A 250ALA A 220 | None | 0.81A | 1xiuA-4g1kA:undetectable | 1xiuA-4g1kA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ia4 | AQUAPORIN (Spinaciaoleracea) |
PF00230(MIP) | 5 | ALA A 257ALA A 258GLN A 261LEU A 110ALA A 111 | None | 0.80A | 1xiuA-4ia4A:undetectable | 1xiuA-4ia4A:22.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 12 | ILE D 268CYH D 269ALA D 271ALA D 272GLN D 275PHE D 313ARG D 316LEU D 326ALA D 327VAL D 342CYH D 432LEU D 436 | None | 0.55A | 1xiuA-4j5xD:30.5 | 1xiuA-4j5xD:77.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jz7 | CARBAMATE KINASE (Giardiaintestinalis) |
PF00696(AA_kinase) | 5 | ILE A 39ALA A 36ALA A 35ALA A 96VAL A 7 | None | 0.87A | 1xiuA-4jz7A:undetectable | 1xiuA-4jz7A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ks8 | SERINE/THREONINE-PROTEIN KINASE PAK 6 (Homo sapiens) |
PF00069(Pkinase) | 5 | ILE A 503GLN A 660LEU A 631VAL A 493LEU A 667 | None | 0.95A | 1xiuA-4ks8A:undetectable | 1xiuA-4ks8A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m88 | EXTRACELLULARLIGAND-BINDINGRECEPTOR (Verminephrobactereiseniae) |
PF13458(Peripla_BP_6) | 5 | ILE A 191ALA A 188ALA A 187LEU A 215ALA A 214 | None | 1.01A | 1xiuA-4m88A:undetectable | 1xiuA-4m88A:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn1 | TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 5 | ILE A 12ALA A 15ALA A 16GLN A 19ALA A 35 | None | 0.54A | 1xiuA-4nn1A:undetectable | 1xiuA-4nn1A:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p47 | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Ochrobactrumanthropi) |
PF03480(DctP) | 5 | ILE A 260ALA A 264ALA A 263LEU A 144ALA A 145 | None | 1.00A | 1xiuA-4p47A:undetectable | 1xiuA-4p47A:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rp8 | ASCORBATE-SPECIFICPERMEASE IICCOMPONENT ULAA (Escherichiacoli) |
PF03611(EIIC-GAT) | 5 | ILE A 160CYH A 161ALA A 163LEU A 110ALA A 111 | None | 0.97A | 1xiuA-4rp8A:undetectable | 1xiuA-4rp8A:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rrj | PROBABLETHREONINE--TRNALIGASE 2 (Aeropyrumpernix) |
PF08915(tRNA-Thr_ED) | 5 | ILE A 58ALA A 55ALA A 54LEU A 99ALA A 98 | None | 0.92A | 1xiuA-4rrjA:undetectable | 1xiuA-4rrjA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uqg | DNA POLYMERASE (Geobacillusstearothermophilus) |
PF00476(DNA_pol_A) | 5 | ILE A 804ALA A 801ALA A 800GLN A 797LEU A 862 | None | 0.97A | 1xiuA-4uqgA:undetectable | 1xiuA-4uqgA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1u | LYND (Lyngbyaaestuarii) |
PF02624(YcaO) | 6 | ILE A 264ALA A 261ALA A 260LEU A 134ALA A 133LEU A 286 | None | 1.24A | 1xiuA-4v1uA:undetectable | 1xiuA-4v1uA:14.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1u | LYND (Lyngbyaaestuarii) |
PF02624(YcaO) | 6 | ILE A 264ALA A 261GLN A 258LEU A 134ALA A 133LEU A 286 | None | 1.37A | 1xiuA-4v1uA:undetectable | 1xiuA-4v1uA:14.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xbo | TRNA(CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ (Escherichiacoli) |
PF00588(SpoU_methylase) | 6 | ALA A 53ALA A 22LEU A 49ALA A 50VAL A 40LEU A 9 | None | 1.08A | 1xiuA-4xboA:undetectable | 1xiuA-4xboA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xbo | TRNA(CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ (Escherichiacoli) |
PF00588(SpoU_methylase) | 6 | ILE A 57ALA A 53ALA A 22LEU A 49ALA A 50LEU A 9 | None | 1.43A | 1xiuA-4xboA:undetectable | 1xiuA-4xboA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgj | UNCHARACTERIZEDPROTEIN (Pectobacteriumatrosepticum) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | ILE A 211ALA A 214ALA A 215LEU A 183ALA A 184 | None | 0.75A | 1xiuA-4xgjA:undetectable | 1xiuA-4xgjA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgj | UNCHARACTERIZEDPROTEIN (Pectobacteriumatrosepticum) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | ILE A 211ALA A 214ALA A 215LEU A 183LEU A 224 | None | 0.99A | 1xiuA-4xgjA:undetectable | 1xiuA-4xgjA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gt5 | PECTATE LYASE (Paenibacillussp. 0602) |
no annotation | 5 | ILE A 117ALA A 116ALA A 115PHE A 132LEU A 39 | None | 0.95A | 1xiuA-5gt5A:undetectable | 1xiuA-5gt5A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hj5 | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Vibrio cholerae) |
PF01182(Glucosamine_iso) | 5 | ILE A 20ALA A 17ALA A 16LEU A 52ALA A 51 | None | 0.99A | 1xiuA-5hj5A:undetectable | 1xiuA-5hj5A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5htv | PUTATIVE XYLULOSEKINASE (Arabidopsisthaliana) |
PF00370(FGGY_N)PF02782(FGGY_C) | 6 | ALA A 239ALA A 422LEU A 242ALA A 243CYH A 231LEU A 161 | None | 1.26A | 1xiuA-5htvA:undetectable | 1xiuA-5htvA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irm | UNCHARACTERIZEDPROTEIN (Oryctolaguscuniculus) |
PF05729(NACHT)PF13516(LRR_6) | 5 | ALA A 900GLN A 897LEU A 927ALA A 926LEU A 871 | None | 1.00A | 1xiuA-5irmA:undetectable | 1xiuA-5irmA:14.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j5v | IMMUNITY PROTEINCDII (Escherichiacoli) |
no annotation | 5 | ILE C 30ALA C 46GLN C 49PHE C 27LEU C 35 | None | 0.95A | 1xiuA-5j5vC:undetectable | 1xiuA-5j5vC:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m49 | AMINOTRANSFERASECLASS-III (Rhizobiumfreirei) |
PF00202(Aminotran_3) | 5 | ILE A 199ALA A 201ALA A 202VAL A 194LEU A 187 | None | 0.98A | 1xiuA-5m49A:undetectable | 1xiuA-5m49A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mzy | GLUTACONATECOA-TRANSFERASEFAMILY, SUBUNIT A (Myxococcusxanthus) |
PF01144(CoA_trans) | 5 | ALA A 189ALA A 190PHE A 157LEU A 113ALA A 116 | None | 1.00A | 1xiuA-5mzyA:undetectable | 1xiuA-5mzyA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0g | PRECORRIN-8XMETHYLMUTASE (Rhodobactercapsulatus) |
no annotation | 6 | ILE A 73ALA A 71ALA A 130LEU A 67ALA A 66VAL A 80 | None | 1.20A | 1xiuA-5n0gA:undetectable | 1xiuA-5n0gA:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nzb | PROFILIN-2 (Betula pendula) |
no annotation | 5 | ILE A 27ALA A 102GLN A 101LEU A 128VAL A 7 | None | 1.00A | 1xiuA-5nzbA:undetectable | 1xiuA-5nzbA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oaf | RUVB-LIKE 1 (Homo sapiens) |
no annotation | 5 | ALA A 82GLN A 85PHE A 93LEU A 87VAL A 66 | None | 1.00A | 1xiuA-5oafA:undetectable | 1xiuA-5oafA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ohs | - (-) |
no annotation | 5 | ILE A 257ALA A 260PHE A 541LEU A 538ALA A 539 | None | 0.79A | 1xiuA-5ohsA:undetectable | 1xiuA-5ohsA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 12 | ILE A 268CYH A 269ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327VAL A 342CYH A 432LEU A 436 | 9CR A 503 (-4.0A)9CR A 503 ( 4.4A)9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-4.3A)9CR A 503 (-3.4A)None9CR A 503 (-3.3A)9CR A 503 ( 4.8A) | 0.50A | 1xiuA-5uanA:30.3 | 1xiuA-5uanA:62.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uwa | PROBABLEPHOSPHOLIPID-BINDINGPROTEIN MLAC (Escherichiacoli) |
PF05494(MlaC) | 5 | ALA A 108GLN A 107LEU A 109ALA A 110VAL A 68 | 8ND A 301 ( 3.9A)NoneNoneNone8ND A 301 ( 4.6A) | 0.95A | 1xiuA-5uwaA:undetectable | 1xiuA-5uwaA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve8 | KAP123 (Kluyveromyceslactis) |
no annotation | 5 | ILE A 302ALA A 305ALA A 306LEU A 262ALA A 265 | None | 0.95A | 1xiuA-5ve8A:undetectable | 1xiuA-5ve8A:12.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyd | PHOSPHODIESTERASE (Salpingoecarosetta) |
no annotation | 6 | ALA A 119ALA A 118LEU A 92ALA A 88VAL A 55LEU A 182 | None | 1.18A | 1xiuA-5vydA:undetectable | 1xiuA-5vydA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | ILE B 247ALA B 229LEU B 378VAL B 277LEU B 354 | None | 0.99A | 1xiuA-5xogB:undetectable | 1xiuA-5xogB:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | RIBOSOMAL PROTEINS19E, PUTATIVE (Trichomonasvaginalis) |
PF01090(Ribosomal_S19e) | 5 | ILE T 68ALA T 65ALA T 64LEU T 25ALA T 26 | None | 0.96A | 1xiuA-5xyiT:undetectable | 1xiuA-5xyiT:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | RIBOSOMAL PROTEINS19E, PUTATIVE (Trichomonasvaginalis) |
PF01090(Ribosomal_S19e) | 5 | ILE T 68ALA T 65LEU T 25ALA T 26LEU T 111 | None | 0.99A | 1xiuA-5xyiT:undetectable | 1xiuA-5xyiT:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zya | SPLICING FACTOR 3BSUBUNIT 1 (Homo sapiens) |
no annotation | 5 | ALA C 672GLN C 669LEU C 712ALA C 711LEU C 644 | None | 1.00A | 1xiuA-5zyaC:undetectable | 1xiuA-5zyaC:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6chj | DIACYLGLYCEROLO-ACYLTRANSFERASE (Marinobacterhydrocarbonoclasticus) |
no annotation | 5 | CYH A 270ALA A 272ALA A 273VAL A 421LEU A 425 | None | 0.77A | 1xiuA-6chjA:undetectable | 1xiuA-6chjA:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 5 | ILE A 129ALA A 132ALA A 133LEU A 267ALA A 266 | None | 0.59A | 1xiuA-6d95A:undetectable | 1xiuA-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6euv | POLYMERASE BASICPROTEIN 2 (Influenza Avirus) |
no annotation | 5 | ILE A 310CYH A 311ALA A 313ALA A 314VAL A 518 | None | 1.02A | 1xiuA-6euvA:undetectable | 1xiuA-6euvA:20.81 |