SIMILAR PATTERNS OF AMINO ACIDS FOR 1X8V_A_ESLA471

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bc7 PROTEIN (ETS-DOMAIN
PROTEIN)

(Homo sapiens) 		PF00178
(Ets) 		4 TYR C  82
PHE C  33
ALA C  38
LEU C  59
 None
 1.11A 1x8vA-1bc7C:
undetectable		 1x8vA-1bc7C:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8z TUBBY PROTEIN

(Mus musculus) 		PF01167
(Tub) 		4 PHE A 498
PHE A 454
ALA A 490
LEU A 285
 None
 1.09A 1x8vA-1c8zA:
0.0		 1x8vA-1c8zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cwu ENOYL ACP REDUCTASE

(Brassica napus) 		PF13561
(adh_short_C2) 		4 TYR A 198
PHE A 246
ALA A 240
MET A 250
 TDB  A 502 (-4.5A)
None
TDB  A 502 ( 3.1A)
None
 1.04A 1x8vA-1cwuA:
undetectable		 1x8vA-1cwuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ddz CARBONIC ANHYDRASE

(Porphyridium
purpureum) 		PF00484
(Pro_CA) 		4 TYR A 444
PHE A 422
ALA A 174
HIS A 205
 None
None
None
ZN  A   1 (-3.2A)
 1.09A 1x8vA-1ddzA:
0.0		 1x8vA-1ddzA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		4 PHE A 149
ALA A 185
LEU A  63
MET A  68
 None
 1.05A 1x8vA-1dl5A:
0.0		 1x8vA-1dl5A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hbx ETS-DOMAIN PROTEIN
ELK-4

(Homo sapiens) 		PF00178
(Ets) 		4 TYR G  82
PHE G  33
ALA G  38
LEU G  59
 None
 1.16A 1x8vA-1hbxG:
undetectable		 1x8vA-1hbxG:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hfu LACCASE 1

(Coprinopsis
cinerea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 PHE A 245
ALA A 249
HIS A 215
LEU A 282
 None
 0.95A 1x8vA-1hfuA:
0.0		 1x8vA-1hfuA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7q ANTHRANILATE
SYNTHASE

(Serratia
marcescens) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		4 PHE A 158
PHE A 173
ALA A 126
LEU A 121
 None
 1.03A 1x8vA-1i7qA:
undetectable		 1x8vA-1i7qA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8t UDP-GALACTOPYRANOSE
MUTASE

(Escherichia
coli) 		PF03275
(GLF)
PF13450
(NAD_binding_8) 		4 TYR A 181
PHE A 182
PHE A  78
ALA A  55
 None
 0.94A 1x8vA-1i8tA:
undetectable		 1x8vA-1i8tA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mdf 2,3-DIHYDROXYBENZOAT
E-AMP LIGASE

(Bacillus
subtilis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 PHE A 322
ALA A 264
LEU A 282
MET A 287
 None
 1.03A 1x8vA-1mdfA:
undetectable		 1x8vA-1mdfA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sfn CONSERVED
HYPOTHETICAL PROTEIN

(Deinococcus
radiodurans) 		PF05899
(Cupin_3) 		4 PHE A1023
ARG A1008
ALA A1210
LEU A1191
 None
 1.18A 1x8vA-1sfnA:
undetectable		 1x8vA-1sfnA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1thg LIPASE 2

(Galactomyces
candidus) 		PF00135
(COesterase) 		4 TYR A 333
ALA A 224
HIS A 225
LEU A 253
 None
 1.16A 1x8vA-1thgA:
undetectable		 1x8vA-1thgA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tza APAG PROTEIN

(Shewanella
oneidensis) 		PF04379
(DUF525) 		4 TYR A  28
PHE A  30
ALA A  56
LEU A 124
 TYR  A  28 ( 1.3A)
PHE  A  30 ( 1.3A)
ALA  A  56 ( 0.0A)
LEU  A 124 ( 0.6A)
 1.14A 1x8vA-1tzaA:
undetectable		 1x8vA-1tzaA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ACTIN-RELATED
PROTEIN 2
ARP2/3 COMPLEX 16KDA
SUBUNIT

(Bos taurus) 		PF00022
(Actin)
PF04699
(P16-Arc) 		4 PHE G  11
ARG G  12
ALA B 279
LEU B 182
 None
 1.12A 1x8vA-1u2vG:
undetectable		 1x8vA-1u2vG:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vyh PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT

(Mus musculus) 		PF00400
(WD40) 		4 ARG C 241
ALA C 210
HIS C 191
MET C 188
 None
 1.12A 1x8vA-1vyhC:
undetectable		 1x8vA-1vyhC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9d ENDOPLASMIC
RETICULUM
MANNOSYL-OLIGOSACCHA
RIDE
1,2-ALPHA-MANNOSIDAS
E

(Homo sapiens) 		PF01532
(Glyco_hydro_47) 		4 TYR A 684
PHE A 605
ARG A 609
LEU A 345
 None
 1.17A 1x8vA-1x9dA:
undetectable		 1x8vA-1x9dA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9g EXO-INULINASE

(Aspergillus
awamori) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 PHE A 441
PHE A 447
ALA A 516
LEU A 392
 None
 0.96A 1x8vA-1y9gA:
undetectable		 1x8vA-1y9gA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7m ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Lactococcus
lactis) 		PF13393
(tRNA-synt_His) 		4 TYR A 125
PHE A 111
ARG A  82
MET A  15
 None
 1.13A 1x8vA-1z7mA:
undetectable		 1x8vA-1z7mA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adc POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 1

(Homo sapiens) 		PF00076
(RRM_1)
PF13893
(RRM_5) 		4 TYR A 361
PHE A 438
HIS A 512
LEU A 508
 None
None
U  B 535 ( 4.3A)
None
 1.16A 1x8vA-2adcA:
undetectable		 1x8vA-2adcA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2anl PLASMEPSIN IV

(Plasmodium
malariae) 		PF00026
(Asp) 		4 PHE A 244
PHE A 241
LEU A 278
MET A 286
 None
 1.02A 1x8vA-2anlA:
undetectable		 1x8vA-2anlA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asn NITROPHORIN 2

(Rhodnius
prolixus) 		PF02087
(Nitrophorin) 		4 PHE X  18
PHE X  42
ALA X 116
LEU X  12
 None
HEM  X 201 ( 4.0A)
None
None
 1.17A 1x8vA-2asnX:
undetectable		 1x8vA-2asnX:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dkh 3-HYDROXYBENZOATE
HYDROXYLASE

(Comamonas
testosteroni) 		PF01494
(FAD_binding_3)
PF07976
(Phe_hydrox_dim) 		4 TYR A 202
PHE A 345
HIS A 390
LEU A 341
 None
 1.07A 1x8vA-2dkhA:
0.4		 1x8vA-2dkhA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fr1 ERYTHROMYCIN
SYNTHASE, ERYAI

(Saccharopolyspora
erythraea) 		PF08659
(KR) 		4 TYR A1898
PHE A1894
PHE A1856
ALA A1802
 None
 1.05A 1x8vA-2fr1A:
undetectable		 1x8vA-2fr1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3r ZGC 92866

(Danio rerio) 		PF04051
(TRAPP) 		4 PHE B  98
PHE B  33
ALA B 141
LEU B 170
 None
 1.06A 1x8vA-2j3rB:
undetectable		 1x8vA-2j3rB:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3w ZGC 92866

(Danio rerio) 		PF04051
(TRAPP) 		4 PHE B  98
PHE B  33
ALA B 141
LEU B 170
 None
 1.08A 1x8vA-2j3wB:
undetectable		 1x8vA-2j3wB:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2khz C-MYC-RESPONSIVE
PROTEIN RCL

(Rattus
norvegicus) 		PF05014
(Nuc_deoxyrib_tr) 		4 TYR A  28
PHE A  14
ALA A  49
HIS A  45
 None
 1.07A 1x8vA-2khzA:
undetectable		 1x8vA-2khzA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o0m TRANSCRIPTIONAL
REGULATOR, SORC
FAMILY

(Enterococcus
faecalis) 		PF04198
(Sugar-bind) 		4 TYR A 275
PHE A 277
ARG A 253
LEU A 297
 None
 0.83A 1x8vA-2o0mA:
undetectable		 1x8vA-2o0mA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o0m TRANSCRIPTIONAL
REGULATOR, SORC
FAMILY

(Enterococcus
faecalis) 		PF04198
(Sugar-bind) 		4 TYR A 275
PHE A 277
HIS A 241
LEU A 297
 None
 1.14A 1x8vA-2o0mA:
undetectable		 1x8vA-2o0mA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8r POLYPHOSPHATE KINASE

(Porphyromonas
gingivalis) 		PF02503
(PP_kinase)
PF13089
(PP_kinase_N)
PF13090
(PP_kinase_C) 		4 TYR A 512
PHE A 504
ALA A 438
LEU A 495
 None
 0.95A 1x8vA-2o8rA:
undetectable		 1x8vA-2o8rA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q0z PROTEIN PRO2281

(Homo sapiens) 		PF02889
(Sec63) 		4 TYR X 207
PHE X 203
ARG X 236
ALA X 305
 None
 1.13A 1x8vA-2q0zX:
undetectable		 1x8vA-2q0zX:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Staphylococcus
saprophyticus) 		PF13407
(Peripla_BP_4) 		4 PHE A  77
PHE A  69
ALA A 305
LEU A 323
 None
 1.17A 1x8vA-2qu7A:
undetectable		 1x8vA-2qu7A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5s PROCESSED GLYCEROL
PHOSPHATE
LIPOTEICHOIC ACID
SYNTHASE

(Staphylococcus
aureus) 		PF00884
(Sulfatase) 		4 TYR A 477
PHE A 500
PHE A 260
HIS A 483
 None
 1.04A 1x8vA-2w5sA:
undetectable		 1x8vA-2w5sA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xf2 CATALASE

(Penicillium
janthinellum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 PHE A 253
ALA A 236
HIS A 204
LEU A 531
 None
 0.99A 1x8vA-2xf2A:
undetectable		 1x8vA-2xf2A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfg ENDOGLUCANASE 1

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9) 		4 PHE A 347
ALA A 257
HIS A 288
LEU A 326
 None
 1.04A 1x8vA-2xfgA:
undetectable		 1x8vA-2xfgA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn8 PUTATIVE CYTOCHROME
P450 125

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 TYR A 294
PHE A 284
ALA A 303
MET A 281
 None
 1.16A 1x8vA-2xn8A:
27.6		 1x8vA-2xn8A:
26.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzg ALANYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD) 		4 TYR A 251
PHE A  66
HIS A  78
LEU A 169
 None
 1.16A 1x8vA-2zzgA:
undetectable		 1x8vA-2zzgA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aat ASPARTATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 TYR A 256
PHE A  79
ALA A 253
LEU A  87
 None
 1.18A 1x8vA-3aatA:
undetectable		 1x8vA-3aatA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3am3 ENOYL-ACP REDUCTASE

(Plasmodium
falciparum) 		PF13561
(adh_short_C2) 		4 TYR A 277
PHE A 368
ALA A 319
MET A 372
 TCL  A 802 (-4.4A)
TCL  A 802 (-4.8A)
TCL  A 802 ( 3.3A)
None
 1.08A 1x8vA-3am3A:
undetectable		 1x8vA-3am3A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bb8 CDP-4-KETO-6-DEOXY-D
-GLUCOSE-3-DEHYDRASE

(Yersinia
pseudotuberculosis) 		PF01041
(DegT_DnrJ_EryC1) 		4 PHE A 231
ALA A 205
HIS A 166
LEU A 174
 None
 1.10A 1x8vA-3bb8A:
undetectable		 1x8vA-3bb8A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cue TRANSPORT PROTEIN
PARTICLE 31 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF04051
(TRAPP) 		4 PHE B  66
ARG B 254
HIS B  74
MET B  69
 None
 1.15A 1x8vA-3cueB:
undetectable		 1x8vA-3cueB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ffh HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Listeria
innocua) 		PF00155
(Aminotran_1_2) 		4 TYR A 233
PHE A  86
ALA A 236
LEU A  79
 None
 1.11A 1x8vA-3ffhA:
undetectable		 1x8vA-3ffhA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzs UNCHARACTERIZED SUSD
SUPERFAMILY PROTEIN

(Bacteroides
fragilis) 		PF12741
(SusD-like) 		4 TYR A 406
PHE A 393
ALA A 317
LEU A 456
 None
 1.02A 1x8vA-3gzsA:
undetectable		 1x8vA-3gzsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 TYR A1067
PHE A1066
LEU A1015
MET A1020
 None
 1.03A 1x8vA-3jb9A:
undetectable		 1x8vA-3jb9A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx2 PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43

(Saccharomyces
cerevisiae) 		no annotation 4 PHE B 480
ARG B 237
ALA B 200
LEU B 227
 None
 1.05A 1x8vA-3kx2B:
undetectable		 1x8vA-3kx2B:
19.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3l4d STEROL 14-ALPHA
DEMETHYLASE

(Leishmania
infantum) 		PF00067
(p450) 		4 PHE A 104
PHE A 109
ALA A 290
LEU A 355
 None
TPF  A 490 (-4.5A)
TPF  A 490 ( 3.4A)
TPF  A 490 (-4.4A)
 1.18A 1x8vA-3l4dA:
38.6		 1x8vA-3l4dA:
32.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3l4d STEROL 14-ALPHA
DEMETHYLASE

(Leishmania
infantum) 		PF00067
(p450) 		4 TYR A 102
PHE A 104
ALA A 290
LEU A 355
 HEM  A 481 (-4.7A)
None
TPF  A 490 ( 3.4A)
TPF  A 490 (-4.4A)
 0.85A 1x8vA-3l4dA:
38.6		 1x8vA-3l4dA:
32.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7z PROBABLE EXOSOME
COMPLEX EXONUCLEASE
2

(Sulfolobus
solfataricus) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		4 TYR A 149
ARG A  38
ALA A 156
LEU A 110
 None
 1.16A 1x8vA-3l7zA:
undetectable		 1x8vA-3l7zA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ljy PUTATIVE ADHESIN

(Parabacteroides
distasonis) 		PF10988
(DUF2807) 		4 TYR A  54
PHE A 119
ALA A 109
LEU A 125
 None
 1.15A 1x8vA-3ljyA:
undetectable		 1x8vA-3ljyA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mvc GLOBIN PROTEIN 6

(Caenorhabditis
elegans) 		PF00042
(Globin) 		4 PHE A 225
ALA A 282
HIS A 286
LEU A 303
 None
HEM  A 500 ( 4.0A)
HEM  A 500 (-3.2A)
HEM  A 500 (-4.6A)
 1.15A 1x8vA-3mvcA:
1.6		 1x8vA-3mvcA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pay PUTATIVE ADHESIN

(Bacteroides
ovatus) 		PF08842
(Mfa2) 		4 TYR A 292
PHE A 289
ALA A 276
MET A 270
 None
 1.15A 1x8vA-3payA:
undetectable		 1x8vA-3payA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT

(Rhodopseudomonas
palustris) 		PF00016
(RuBisCO_large) 		4 TYR A 108
PHE A 112
PHE A 308
LEU A  87
 None
 1.18A 1x8vA-3qfwA:
undetectable		 1x8vA-3qfwA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3

(Saccharomyces
cerevisiae;
Schizosaccharomyces
pombe) 		PF11976
(Rad60-SLD)
no annotation 		4 TYR B 803
ARG A  69
ALA A  62
LEU B 774
 CL  A1002 (-4.9A)
CL  A1002 ( 3.3A)
None
None
 1.01A 1x8vA-3tixB:
undetectable		 1x8vA-3tixB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uuf LIP1, SECRETORY
LIPASE (FAMILY 3)

(Malassezia
globosa) 		PF01764
(Lipase_3) 		4 TYR A 196
PHE A 198
ALA A  95
LEU A  47
 None
 1.15A 1x8vA-3uufA:
undetectable		 1x8vA-3uufA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6q TYROSINASE

(Aspergillus
oryzae) 		PF00264
(Tyrosinase) 		4 TYR A 145
ARG A 153
ALA A 149
LEU A 378
 None
 1.10A 1x8vA-3w6qA:
undetectable		 1x8vA-3w6qA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wh9 ENDO-BETA-1,4-MANNAN
ASE

(Aspergillus
niger) 		PF00150
(Cellulase) 		4 TYR A 143
PHE A 133
HIS A  73
MET A 118
 None
 1.08A 1x8vA-3wh9A:
undetectable		 1x8vA-3wh9A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		4 PHE A 279
ARG A 658
ALA A 670
MET A 251
 None
 1.19A 1x8vA-3x1lA:
undetectable		 1x8vA-3x1lA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1

(Lupinus luteus) 		PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N) 		4 PHE A 270
ALA A 343
LEU A 314
MET A 273
 None
 1.07A 1x8vA-3zk4A:
undetectable		 1x8vA-3zk4A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zpn PHOTOSYSTEM II
REACTION CENTER
PSB28 PROTEIN

(Thermosynechococcus
elongatus) 		PF03912
(Psb28) 		4 TYR A 102
PHE A  98
ALA A   3
MET A  56
 None
 0.93A 1x8vA-3zpnA:
undetectable		 1x8vA-3zpnA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0k CULLIN-4A

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		4 PHE A 449
HIS A 412
LEU A 366
MET A 361
 None
 1.15A 1x8vA-4a0kA:
3.5		 1x8vA-4a0kA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aez MITOTIC SPINDLE
CHECKPOINT COMPONENT
MAD3

(Schizosaccharomyces
pombe) 		PF08311
(Mad3_BUB1_I) 		4 TYR C 191
PHE C 187
ARG C 197
ALA C 157
 None
 1.08A 1x8vA-4aezC:
undetectable		 1x8vA-4aezC:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aez MITOTIC SPINDLE
CHECKPOINT COMPONENT
MAD3

(Schizosaccharomyces
pombe) 		PF08311
(Mad3_BUB1_I) 		4 TYR C 191
PHE C 187
ARG C 197
ALA C 169
 None
 1.13A 1x8vA-4aezC:
undetectable		 1x8vA-4aezC:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aj9 CATALASE-3

(Neurospora
crassa) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 PHE A 291
ALA A 274
HIS A 242
LEU A 569
 None
 1.05A 1x8vA-4aj9A:
undetectable		 1x8vA-4aj9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmh ACETYLTRANSFERASE

(Streptomyces
sviceus) 		PF00583
(Acetyltransf_1) 		4 TYR A 138
PHE A 134
ALA A 100
HIS A 187
 None
 1.17A 1x8vA-4bmhA:
undetectable		 1x8vA-4bmhA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddw REVERSE GYRASE

(Thermotoga
maritima) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 PHE A 437
PHE A 445
ALA A 404
LEU A 424
 None
 0.99A 1x8vA-4ddwA:
undetectable		 1x8vA-4ddwA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e14 KYNURENINE
FORMAMIDASE

(Drosophila
melanogaster) 		PF07859
(Abhydrolase_3) 		4 PHE A 248
ALA A 158
HIS A 161
LEU A 125
 None
SEB  A 157 ( 3.3A)
None
None
 0.96A 1x8vA-4e14A:
undetectable		 1x8vA-4e14A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4elj RETINOBLASTOMA-ASSOC
IATED PROTEIN

(Homo sapiens) 		PF01857
(RB_B)
PF01858
(RB_A)
PF11934
(DUF3452) 		4 TYR A 225
PHE A 226
ALA A 201
LEU A 303
 None
 1.08A 1x8vA-4eljA:
undetectable		 1x8vA-4eljA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irt UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF15892
(BNR_4) 		4 TYR A 197
PHE A  40
ARG A 333
HIS A 110
 None
 1.08A 1x8vA-4irtA:
undetectable		 1x8vA-4irtA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6n AMINODEOXYCHORISMATE
LYASE

(Saccharomyces
cerevisiae) 		PF01063
(Aminotran_4) 		4 TYR A 258
PHE A 288
LEU A 326
MET A 296
 PLP  A 500 (-3.6A)
None
PLP  A 500 (-4.1A)
None
 1.11A 1x8vA-4k6nA:
undetectable		 1x8vA-4k6nA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kk1 TUBEROUS SCLEROSIS 1
PROTEIN HOMOLOG

(Schizosaccharomyces
pombe) 		PF04388
(Hamartin) 		4 TYR A 276
PHE A 354
HIS A 392
LEU A 388
 None
 1.06A 1x8vA-4kk1A:
undetectable		 1x8vA-4kk1A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o4o PHYCOCYANOBILIN
LYASE CPCT

(Nostoc sp. PCC
7120) 		PF06206
(CpeT) 		4 PHE A 152
PHE A  18
ARG A 186
LEU A  72
 None
 1.16A 1x8vA-4o4oA:
undetectable		 1x8vA-4o4oA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qb9 ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN

(Mycolicibacterium
smegmatis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 TYR A 219
ARG A 177
ALA A 246
LEU A 239
 None
 1.08A 1x8vA-4qb9A:
undetectable		 1x8vA-4qb9A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s17 GLUTAMINE SYNTHETASE

(Bifidobacterium
adolescentis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 PHE A  80
ARG A  25
LEU A 256
MET A 203
 None
 1.14A 1x8vA-4s17A:
undetectable		 1x8vA-4s17A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Drosophila
melanogaster) 		PF07034
(ORC3_N) 		4 PHE C 318
PHE C 326
ALA C 289
HIS C 291
 None
 0.95A 1x8vA-4xgcC:
undetectable		 1x8vA-4xgcC:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xpr ALPHA-GLUCOSIDASE

(Pseudopedobacter
saltans) 		PF01055
(Glyco_hydro_31)
PF17137
(DUF5110) 		4 TYR A 100
PHE A 450
PHE A 137
ALA A 212
 EDO  A1001 (-4.5A)
EDO  A1001 (-4.8A)
None
None
 1.13A 1x8vA-4xprA:
undetectable		 1x8vA-4xprA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu5 IMMUNE INHIBITOR A,
METALLOPROTEASE

(Bacillus cereus) 		PF05547
(Peptidase_M6) 		4 PHE A 193
ARG A  56
ALA A 373
LEU A 210
 None
 1.12A 1x8vA-4yu5A:
undetectable		 1x8vA-4yu5A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5apa ASPARTYL/ASPARAGINYL
BETA-HYDROXYLASE

(Homo sapiens) 		PF05118
(Asp_Arg_Hydrox) 		4 TYR A 667
PHE A 612
ALA A 640
MET A 605
 None
 1.04A 1x8vA-5apaA:
undetectable		 1x8vA-5apaA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 TYR A 315
PHE A 329
ALA A 122
LEU A 293
 None
 1.09A 1x8vA-5ereA:
undetectable		 1x8vA-5ereA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		4 TYR A 334
PHE A 330
ALA A 306
LEU A 374
 None
 0.95A 1x8vA-5ghkA:
undetectable		 1x8vA-5ghkA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hhl RETRON-TYPE REVERSE
TRANSCRIPTASE

([Eubacterium]
rectale) 		PF00078
(RVT_1) 		4 TYR A 102
PHE A 106
ALA A  95
LEU A 202
 None
 1.04A 1x8vA-5hhlA:
undetectable		 1x8vA-5hhlA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hlb PENICILLIN-BINDING
PROTEIN 1B

(Escherichia
coli) 		PF00905
(Transpeptidase)
PF00912
(Transgly)
PF14814
(UB2H) 		4 PHE A 480
ARG A 660
ALA A 667
LEU A 757
 None
 1.16A 1x8vA-5hlbA:
undetectable		 1x8vA-5hlbA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5in8 ARISTOLOCHENE
SYNTHASE

(Aspergillus
terreus) 		no annotation 4 TYR A  61
PHE A  62
LEU A 177
MET A 182
 None
 1.15A 1x8vA-5in8A:
undetectable		 1x8vA-5in8A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iqk BETA-LACTAMASE RM3

(uncultured
bacterium) 		PF00753
(Lactamase_B) 		4 PHE A 222
ARG A 295
HIS A 110
LEU A 153
 None
None
ZN  A 401 (-3.1A)
None
 1.09A 1x8vA-5iqkA:
undetectable		 1x8vA-5iqkA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j4f UNCHARACTERIZED
PROTEIN

(Helicobacter
pylori) 		no annotation 4 PHE A  59
ALA A  44
HIS A  42
LEU A  94
 None
 1.18A 1x8vA-5j4fA:
undetectable		 1x8vA-5j4fA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7z PUTATIVE SECRETED
ENDOGLYCOSYLCERAMIDA
SE

(Rhodococcus
hoagii) 		PF00150
(Cellulase) 		4 TYR A 410
PHE A 408
HIS A  54
LEU A  52
 None
 1.11A 1x8vA-5j7zA:
undetectable		 1x8vA-5j7zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jlc LANOSTEROL 14-ALPHA
DEMETHYLASE

([Candida]
glabrata) 		PF00067
(p450) 		4 TYR A 127
PHE A 242
PHE A 237
LEU A 384
 1YN  A 602 ( 3.8A)
1YN  A 602 ( 4.5A)
1YN  A 602 (-4.5A)
HEM  A 601 (-3.6A)
 1.04A 1x8vA-5jlcA:
34.6		 1x8vA-5jlcA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jz8 ASPARTYL/ASPARAGINYL
BETA-HYDROXYLASE

(Homo sapiens) 		PF05118
(Asp_Arg_Hydrox)
PF13181
(TPR_8)
PF13432
(TPR_16) 		4 TYR A 667
PHE A 612
ALA A 640
MET A 605
 None
ACT  A 803 (-4.8A)
None
None
 1.00A 1x8vA-5jz8A:
undetectable		 1x8vA-5jz8A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldt MOMP PORIN

(Campylobacter
jejuni) 		PF05538
(Campylo_MOMP) 		4 PHE A  50
PHE A 405
ALA A  46
LEU A  85
 None
 1.09A 1x8vA-5ldtA:
undetectable		 1x8vA-5ldtA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lun 2-OXOGLUTARATE-DEPEN
DENT
ETHYLENE/SUCCINATE-F
ORMING ENZYME

(Pseudomonas
savastanoi) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		4 PHE A  58
ARG A 321
ALA A  80
LEU A  63
 None
 1.10A 1x8vA-5lunA:
0.9		 1x8vA-5lunA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mvh BACCELL_00856

(Bacteroides
cellulosilyticus) 		PF15892
(BNR_4) 		4 TYR A 197
PHE A  40
ARG A 333
HIS A 110
 None
 1.08A 1x8vA-5mvhA:
undetectable		 1x8vA-5mvhA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 4 PHE A 563
ALA A 588
HIS A 583
LEU A 571
 None
 1.06A 1x8vA-5nd1A:
undetectable		 1x8vA-5nd1A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5unc PHOSPHOENOLPYRUVATE
PHOSPHOMUTASE

(Streptomyces
platensis) 		PF13714
(PEP_mutase) 		4 TYR A 231
PHE A 137
ALA A 250
HIS A 252
 None
None
TLA  A 401 (-3.5A)
None
 1.02A 1x8vA-5uncA:
undetectable		 1x8vA-5uncA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyh CBSA

(Xanthomonas
oryzae) 		no annotation 4 TYR A 245
PHE A 314
ARG A 247
LEU A 232
 None
 1.10A 1x8vA-5xyhA:
undetectable		 1x8vA-5xyhA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2v RUBISCO OPERON
TRANSCRIPTIONAL
REGULATOR

(Synechocystis
sp. PCC 6803) 		no annotation 4 PHE A 286
PHE A 161
ALA A 103
LEU A 125
 None
 1.02A 1x8vA-5y2vA:
undetectable		 1x8vA-5y2vA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2w RUBISCO OPERON
TRANSCRIPTIONAL
REGULATOR

(Synechocystis
sp. PCC 6803) 		no annotation 4 PHE A 286
PHE A 161
ALA A 103
LEU A 125
 None
 1.03A 1x8vA-5y2wA:
undetectable		 1x8vA-5y2wA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yem CATALASE

(Mycothermus
thermophilus) 		no annotation 4 PHE A 271
ALA A 254
HIS A 222
LEU A 550
 None
 1.11A 1x8vA-5yemA:
undetectable		 1x8vA-5yemA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yo8 TETRAPRENYL-BETA-CUR
CUMENE SYNTHASE

(Bacillus
alcalophilus) 		no annotation 4 TYR A  80
PHE A  76
ALA A 111
LEU A 160
 None
 1.09A 1x8vA-5yo8A:
undetectable		 1x8vA-5yo8A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yti FLAGELLAR HOOK
ASSOCIATED PROTEIN
TYPE 3 FLGL

(Legionella
pneumophila) 		no annotation 4 PHE A 136
ARG A 163
ALA A  72
LEU A 345
 None
 1.15A 1x8vA-5ytiA:
undetectable		 1x8vA-5ytiA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5

(Oryctolagus
cuniculus) 		no annotation 4 PHE A 537
PHE A 504
LEU A 568
MET A 570
 None
 1.18A 1x8vA-6b5vA:
0.5		 1x8vA-6b5vA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gun -

(-) 		no annotation 4 TYR A  54
PHE A 172
PHE A 295
MET A 171
 None
 1.11A 1x8vA-6gunA:
undetectable		 1x8vA-6gunA:
undetectable