SIMILAR PATTERNS OF AMINO ACIDS FOR 1WSV_A_THHA3001_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brw PROTEIN (PYRIMIDINE
NUCLEOSIDE
PHOSPHORYLASE)

(Geobacillus
stearothermophilus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		3 ASP A 352
GLU A 213
TYR A 429
 None
 0.69A 1wsvA-1brwA:
undetectable		 1wsvA-1brwA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1clx XYLANASE A

(Cellvibrio
japonicus) 		PF00331
(Glyco_hydro_10) 		3 ASP A 134
GLU A 246
TYR A 178
 None
 0.82A 1wsvA-1clxA:
0.0		 1wsvA-1clxA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1t LYSYL-TRNA
SYNTHETASE, HEAT
INDUCIBLE

(Escherichia
coli) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		3 ASP A 431
GLU A 441
TYR A 456
 None
 0.70A 1wsvA-1e1tA:
0.0		 1wsvA-1e1tA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h81 POLYAMINE OXIDASE

(Zea mays) 		PF01593
(Amino_oxidase) 		3 ASP A 195
GLU A 317
TYR A 165
 None
 0.75A 1wsvA-1h81A:
0.0		 1wsvA-1h81A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kho ALPHA-TOXIN

(Clostridium
perfringens) 		PF00882
(Zn_dep_PLPC)
PF01477
(PLAT) 		3 ASP A 356
GLU A 267
TYR A 338
 None
 0.83A 1wsvA-1khoA:
undetectable		 1wsvA-1khoA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 2

(Streptomyces
coelicolor) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 ASP B 192
GLU B 131
TYR B 137
 None
 0.76A 1wsvA-1tqyB:
0.0		 1wsvA-1tqyB:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
RE-EXPORTER

(Saccharomyces
cerevisiae) 		PF03378
(CAS_CSE1)
PF03810
(IBN_N)
PF08506
(Cse1) 		3 ASP C 360
GLU C 571
TYR C 513
 None
 0.68A 1wsvA-1wa5C:
undetectable		 1wsvA-1wa5C:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkb LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		3 ASP A 555
GLU A 164
TYR A 538
 None
 0.73A 1wsvA-1wkbA:
0.2		 1wsvA-1wkbA:
17.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wop AMINOMETHYLTRANSFERA
SE

(Thermotoga
maritima) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		3 ASP A  96
GLU A 195
TYR A 168
 FFO  A2887 (-3.1A)
FFO  A2887 (-2.8A)
None
 0.83A 1wsvA-1wopA:
50.1		 1wsvA-1wopA:
34.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1wsv AMINOMETHYLTRANSFERA
SE

(Homo sapiens) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		3 ASP A 101
GLU A 204
TYR A 371
 ASP  A 101 (-0.6A)
GLU  A 204 (-0.5A)
TYR  A 371 (-1.3A)
 0.02A 1wsvA-1wsvA:
66.6		 1wsvA-1wsvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wu8 HYPOTHETICAL PROTEIN
PH0463

(Pyrococcus
horikoshii) 		PF01887
(SAM_adeno_trans) 		3 ASP A 228
GLU A 210
TYR A 212
 None
 0.78A 1wsvA-1wu8A:
undetectable		 1wsvA-1wu8A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		3 ASP A 555
GLU A 164
TYR A 538
 None
 0.76A 1wsvA-1wz2A:
undetectable		 1wsvA-1wz2A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yqe HYPOTHETICAL UPF0204
PROTEIN AF0625

(Archaeoglobus
fulgidus) 		PF04414
(tRNA_deacylase) 		3 ASP A  10
GLU A 135
TYR A 116
 None
 0.66A 1wsvA-1yqeA:
undetectable		 1wsvA-1yqeA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2apl HYPOTHETICAL PROTEIN
PG0816

(Porphyromonas
gingivalis) 		PF08989
(DUF1896) 		3 ASP A 120
GLU A  64
TYR A  19
 None
 0.85A 1wsvA-2aplA:
undetectable		 1wsvA-2aplA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d8b TWINFILIN-1

(Mus musculus) 		PF00241
(Cofilin_ADF) 		3 ASP A  79
GLU A  51
TYR A 104
 None
 0.84A 1wsvA-2d8bA:
undetectable		 1wsvA-2d8bA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3n ALPHA-GLUCOSIDASE

(Sulfolobus
solfataricus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 ASP A 157
GLU A 536
TYR A 544
 None
 0.76A 1wsvA-2g3nA:
undetectable		 1wsvA-2g3nA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gs8 MEVALONATE
PYROPHOSPHATE
DECARBOXYLASE

(Streptococcus
pyogenes) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		3 ASP A 194
GLU A  23
TYR A  19
 None
None
EDO  A 509 (-4.6A)
 0.83A 1wsvA-2gs8A:
0.9		 1wsvA-2gs8A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwg 4-OXALOMESACONATE
HYDRATASE

(Rhodopseudomonas
palustris) 		PF04909
(Amidohydro_2) 		3 ASP A 268
GLU A 317
TYR A 322
 None
 0.78A 1wsvA-2gwgA:
undetectable		 1wsvA-2gwgA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzs RNA POLYMERASE II
MEDIATOR COMPLEX
SUBUNIT 18

(Saccharomyces
cerevisiae) 		PF09637
(Med18) 		3 ASP B 297
GLU B 212
TYR B 215
 None
 0.77A 1wsvA-2hzsB:
2.2		 1wsvA-2hzsB:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqf CATALASE

(Helicobacter
pylori) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 ASP A 194
GLU A 440
TYR A 175
 None
 0.82A 1wsvA-2iqfA:
undetectable		 1wsvA-2iqfA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jdx PROTEIN
(L-ARGININE:GLYCINE
AMIDINOTRANSFERASE)

(Homo sapiens) 		no annotation 3 ASP A 298
GLU A 101
TYR A 227
 None
 0.85A 1wsvA-2jdxA:
undetectable		 1wsvA-2jdxA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oo4 NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 2

(Homo sapiens) 		PF00066
(Notch)
PF06816
(NOD)
PF07684
(NODP) 		3 ASP A1454
GLU A1617
TYR A1592
 CA  A5001 (-3.4A)
None
None
 0.45A 1wsvA-2oo4A:
undetectable		 1wsvA-2oo4A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prd PYROPHOSPHATE
PHOSPHOHYDROLASE

(Thermus
thermophilus) 		PF00719
(Pyrophosphatase) 		3 ASP A  65
GLU A  31
TYR A 139
 None
None
SO4  A 175 (-4.3A)
 0.81A 1wsvA-2prdA:
undetectable		 1wsvA-2prdA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qqp LARGE CAPSID PROTEIN

(Providence
virus) 		PF03566
(Peptidase_A21) 		3 ASP A 365
GLU A 166
TYR A 202
 None
 0.83A 1wsvA-2qqpA:
undetectable		 1wsvA-2qqpA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uxs INORGANIC
PYROPHOSPHATASE

(Mycobacterium
tuberculosis) 		PF00719
(Pyrophosphatase) 		3 ASP A  59
GLU A  15
TYR A 133
 None
None
PO4  A1167 (-4.6A)
 0.82A 1wsvA-2uxsA:
undetectable		 1wsvA-2uxsA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vat ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE

(Acremonium
chrysogenum) 		PF00561
(Abhydrolase_1) 		3 ASP A  34
GLU A  10
TYR A  39
 None
 0.80A 1wsvA-2vatA:
undetectable		 1wsvA-2vatA:
25.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wae PENICILLIN-BINDING
PROTEIN 2B

(Streptococcus
pneumoniae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		3 ASP A 580
GLU A 484
TYR A 531
 None
 0.85A 1wsvA-2waeA:
undetectable		 1wsvA-2waeA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wau ERYTHROCYTE MEMBRANE
PROTEIN 1 (PFEMP1)

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		3 ASP A2430
GLU A2517
TYR A2413
 None
 0.80A 1wsvA-2wauA:
undetectable		 1wsvA-2wauA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		3 ASP A 139
GLU A 117
TYR A 123
 None
EDO  A1753 (-2.8A)
None
 0.76A 1wsvA-2xijA:
undetectable		 1wsvA-2xijA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y6p 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Aquifex
aeolicus) 		PF02348
(CTP_transf_3) 		3 ASP A 133
GLU A  96
TYR A 170
 None
None
IPA  A1236 ( 4.0A)
 0.81A 1wsvA-2y6pA:
undetectable		 1wsvA-2y6pA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y96 DUAL SPECIFICITY
PHOSPHATASE DUPD1

(Homo sapiens) 		PF00782
(DSPc) 		3 ASP A 139
GLU A  57
TYR A 161
 None
 0.78A 1wsvA-2y96A:
undetectable		 1wsvA-2y96A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		3 ASP A 380
GLU A 155
TYR A 239
 CA  A1525 ( 3.4A)
None
None
 0.81A 1wsvA-2yeqA:
undetectable		 1wsvA-2yeqA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yew E1 ENVELOPE
GLYCOPROTEIN

(Barmah Forest
virus) 		PF01589
(Alpha_E1_glycop) 		3 ASP B 202
GLU B 246
TYR B 180
 None
 0.84A 1wsvA-2yewB:
undetectable		 1wsvA-2yewB:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayf NITRIC OXIDE
REDUCTASE

(Geobacillus
stearothermophilus) 		PF00115
(COX1) 		3 ASP A 125
GLU A 108
TYR A 162
 None
 0.72A 1wsvA-3ayfA:
undetectable		 1wsvA-3ayfA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dl1 PUTATIVE
METAL-DEPENDENT
HYDROLASE

(Klebsiella
pneumoniae) 		PF06167
(Peptidase_M90) 		3 ASP A 134
GLU A 212
TYR A 220
 None
 0.83A 1wsvA-3dl1A:
undetectable		 1wsvA-3dl1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzb PREPHENATE
DEHYDROGENASE

(Streptococcus
thermophilus) 		PF02153
(PDH) 		3 ASP A  38
GLU A  59
TYR A  79
 None
 0.81A 1wsvA-3dzbA:
undetectable		 1wsvA-3dzbA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0s UNCHARACTERIZED
PROTEIN

(Chlorobaculum
tepidum) 		PF05235
(CHAD) 		3 ASP A 330
GLU A 476
TYR A 308
 None
 0.78A 1wsvA-3e0sA:
undetectable		 1wsvA-3e0sA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e2s PROLINE
DEHYDROGENASE

(Escherichia
coli) 		PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 ASP A 370
GLU A 559
TYR A 466
 PRO  A   1 ( 3.8A)
FAD  A2001 (-2.8A)
None
 0.83A 1wsvA-3e2sA:
undetectable		 1wsvA-3e2sA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ea0 ATPASE, PARA FAMILY

(Chlorobaculum
tepidum) 		PF13614
(AAA_31) 		3 ASP A 234
GLU A 173
TYR A 118
 None
 0.86A 1wsvA-3ea0A:
undetectable		 1wsvA-3ea0A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emj INORGANIC
PYROPHOSPHATASE

(Rickettsia
prowazekii) 		PF00719
(Pyrophosphatase) 		3 ASP A  65
GLU A  20
TYR A 141
 None
 0.81A 1wsvA-3emjA:
undetectable		 1wsvA-3emjA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdc MULTICOPPER OXIDASE

(Arthrobacter
sp. FB24) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ASP A 173
GLU A 164
TYR A 242
 None
 0.77A 1wsvA-3gdcA:
undetectable		 1wsvA-3gdcA:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gir AMINOMETHYLTRANSFERA
SE

(Bartonella
henselae) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		3 ASP A 108
GLU A 201
TYR A 369
 None
 0.27A 1wsvA-3girA:
50.0		 1wsvA-3girA:
40.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goc ENDONUCLEASE V

(Streptomyces
avermitilis) 		PF04493
(Endonuclease_5) 		3 ASP A 217
GLU A  93
TYR A 116
 MG  A 301 (-3.2A)
None
None
 0.83A 1wsvA-3gocA:
undetectable		 1wsvA-3gocA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm7 ALLANTOINASE

(Bacillus
halodurans) 		PF01979
(Amidohydro_1) 		3 ASP A 315
GLU A 220
TYR A 211
 ZN  A 447 (-2.8A)
None
None
 0.84A 1wsvA-3hm7A:
undetectable		 1wsvA-3hm7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 4

(Thermus
thermophilus) 		PF00346
(Complex1_49kDa) 		3 ASP 4  86
GLU 4 282
TYR 4 257
 None
 0.83A 1wsvA-3i9v4:
undetectable		 1wsvA-3i9v4:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ks7 PUTATIVE PUTATIVE
PNGASE F

(Bacteroides
fragilis) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		3 ASP A 369
GLU A 373
TYR A 410
 None
EDO  A 420 ( 3.5A)
None
 0.85A 1wsvA-3ks7A:
undetectable		 1wsvA-3ks7A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lo0 INORGANIC
PYROPHOSPHATASE

(Ehrlichia
chaffeensis) 		PF00719
(Pyrophosphatase) 		3 ASP A  66
GLU A  21
TYR A 142
 None
 0.77A 1wsvA-3lo0A:
undetectable		 1wsvA-3lo0A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ojy COMPLEMENT COMPONENT
C8 BETA CHAIN

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00090
(TSP_1)
PF01823
(MACPF) 		3 ASP B 244
GLU B 192
TYR B 224
 None
 0.80A 1wsvA-3ojyB:
undetectable		 1wsvA-3ojyB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4o UNCHARACTERIZED
PROTEIN MJ0754

(Methanocaldococcus
jannaschii) 		PF09968
(DUF2202) 		3 ASP A 119
GLU A 170
TYR A 161
 None
 0.80A 1wsvA-3q4oA:
undetectable		 1wsvA-3q4oA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sz4 EXONUCLEASE

(Laribacter
hongkongensis) 		PF09588
(YqaJ) 		3 ASP A  90
GLU A 192
TYR A  39
 None
 0.78A 1wsvA-3sz4A:
undetectable		 1wsvA-3sz4A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tca AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN

(Mus musculus) 		PF00169
(PH)
PF00788
(RA) 		3 ASP A 428
GLU A 299
TYR A 277
 None
 0.79A 1wsvA-3tcaA:
undetectable		 1wsvA-3tcaA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A

(Bacillus
subtilis) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		3 ASP A 825
GLU A 502
TYR A 911
 None
 0.84A 1wsvA-3u44A:
undetectable		 1wsvA-3u44A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uto TWITCHIN

(Caenorhabditis
elegans) 		PF00041
(fn3)
PF00069
(Pkinase)
PF07679
(I-set) 		3 ASP A 440
GLU A   8
TYR A  41
 None
 0.73A 1wsvA-3utoA:
1.0		 1wsvA-3utoA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8s ADP-DEPENDENT
GLUCOKINASE

(Thermococcus
litoralis) 		PF04587
(ADP_PFK_GK) 		3 ASP A 451
GLU A 308
TYR A 354
 GLC  A 468 (-2.9A)
GOL  A1468 (-2.9A)
AMP  A1472 ( 4.0A)
 0.79A 1wsvA-4b8sA:
undetectable		 1wsvA-4b8sA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		3 ASP A 704
GLU A 849
TYR A 927
 None
 0.79A 1wsvA-4bedA:
undetectable		 1wsvA-4bedA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2i LARGE T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF06431
(Polyoma_lg_T_C) 		3 ASP A 429
GLU A 473
TYR A 531
 None
 0.65A 1wsvA-4e2iA:
undetectable		 1wsvA-4e2iA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gtn ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Acinetobacter
sp. ADP1) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		3 ASP A 244
GLU A 273
TYR A 333
 None
 0.80A 1wsvA-4gtnA:
undetectable		 1wsvA-4gtnA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hka TRYPTOPHAN
2,3-DIOXYGENASE

(Drosophila
melanogaster) 		PF03301
(Trp_dioxygenase) 		3 ASP A 165
GLU A 180
TYR A 344
 None
 0.82A 1wsvA-4hkaA:
undetectable		 1wsvA-4hkaA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkl BETA-GLUCURONIDASE

(Streptococcus
agalactiae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 ASP A  46
GLU A 157
TYR A 330
 None
 0.74A 1wsvA-4jklA:
undetectable		 1wsvA-4jklA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kd5 ABC-TYPE TRANSPORT
SYSTEM,
MOLYBDENUM-SPECIFIC
EXTRACELLULAR
SOLUTE-BINDING
PROTEIN

(Clostridioides
difficile) 		no annotation 3 ASP C 120
GLU C 223
TYR C 205
 None
 0.80A 1wsvA-4kd5C:
undetectable		 1wsvA-4kd5C:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kvg AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN

(Mus musculus) 		PF00169
(PH)
PF00788
(RA) 		3 ASP B 428
GLU B 299
TYR B 277
 EDO  B 501 (-2.8A)
None
None
 0.74A 1wsvA-4kvgB:
undetectable		 1wsvA-4kvgB:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o8a BIFUNCTIONAL PROTEIN
PUTA

(Escherichia
coli) 		PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 ASP A 370
GLU A 559
TYR A 466
 FAD  A2001 ( 3.7A)
FAD  A2001 (-2.7A)
None
 0.74A 1wsvA-4o8aA:
undetectable		 1wsvA-4o8aA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmk TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN EXOU

(Pseudomonas
fluorescens) 		PF01734
(Patatin) 		3 ASP A 240
GLU A 630
TYR A 613
 None
 0.76A 1wsvA-4qmkA:
undetectable		 1wsvA-4qmkA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9x COPPER HOMEOSTASIS
PROTEIN CUTC

(Bacillus
anthracis) 		PF03932
(CutC) 		3 ASP A 123
GLU A   3
TYR A  29
 None
 0.76A 1wsvA-4r9xA:
undetectable		 1wsvA-4r9xA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uym 14-ALPHA STEROL
DEMETHYLASE

(Aspergillus
fumigatus) 		PF00067
(p450) 		3 ASP A 435
GLU A 466
TYR A 442
 None
 0.67A 1wsvA-4uymA:
undetectable		 1wsvA-4uymA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0e PUTATIVE DIOXYGENASE

(Mycobacteroides
abscessus) 		PF02668
(TauD) 		3 ASP A 256
GLU A  44
TYR A  11
 MPD  A 402 (-3.5A)
None
None
 0.80A 1wsvA-4y0eA:
undetectable		 1wsvA-4y0eA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdl O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Homo sapiens) 		PF05889
(SepSecS) 		3 ASP A 201
GLU A 211
TYR A 245
 None
 0.79A 1wsvA-4zdlA:
undetectable		 1wsvA-4zdlA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zm6 N-ACETYL-BETA-D
GLUCOSAMINIDASE

(Rhizomucor
miehei) 		PF00583
(Acetyltransf_1)
PF00933
(Glyco_hydro_3) 		3 ASP A 190
GLU A  82
TYR A 501
 None
 0.70A 1wsvA-4zm6A:
undetectable		 1wsvA-4zm6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bza BETA-N-ACETYLHEXOSAM
INIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3) 		3 ASP A 171
GLU A  65
TYR A  35
 CD  A 502 (-2.3A)
None
None
 0.81A 1wsvA-5bzaA:
undetectable		 1wsvA-5bzaA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d8g TRYPTOPHANASE

(Escherichia
coli) 		PF01212
(Beta_elim_lyase) 		3 ASP A 172
GLU A 182
TYR A 220
 None
 0.84A 1wsvA-5d8gA:
undetectable		 1wsvA-5d8gA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzq TOXIN-LIKE PROTEIN

(Paenibacillus
larvae) 		PF03496
(ADPrib_exo_Tox) 		3 ASP A  76
GLU A 113
TYR A 106
 None
 0.79A 1wsvA-5dzqA:
undetectable		 1wsvA-5dzqA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B

(Neotoma lepida) 		PF00067
(p450) 		3 ASP A 266
GLU A 250
TYR A 244
 None
 0.81A 1wsvA-5e0eA:
undetectable		 1wsvA-5e0eA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e32 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		3 ASP A  77
GLU A 255
TYR A 258
 None
 0.84A 1wsvA-5e32A:
undetectable		 1wsvA-5e32A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f0l VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 26A

(Homo sapiens) 		PF03643
(Vps26) 		3 ASP B 142
GLU B  94
TYR B 107
 None
EDO  B 409 (-3.3A)
None
 0.79A 1wsvA-5f0lB:
undetectable		 1wsvA-5f0lB:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1n MHC CLASS I ANTIGEN

(Canis lupus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		3 ASP A 102
GLU A 213
TYR A 210
 None
 0.81A 1wsvA-5f1nA:
undetectable		 1wsvA-5f1nA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihw SERINE-ASPARTATE
REPEAT-CONTAINING
PROTEIN E

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C) 		3 ASP A 342
GLU A 449
TYR A 554
 None
 0.85A 1wsvA-5ihwA:
undetectable		 1wsvA-5ihwA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5it9 RIBOSOMAL PROTEIN
RACK1

(Kluyveromyces
lactis) 		PF01092
(Ribosomal_S6e) 		3 ASP g  77
GLU g 101
TYR g  62
 None
 0.84A 1wsvA-5it9g:
undetectable		 1wsvA-5it9g:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k50 L-THREONINE
3-DEHYDROGENASE

(Trypanosoma
brucei) 		no annotation 3 ASP A1058
GLU A1068
TYR A1110
 None
 0.84A 1wsvA-5k50A:
undetectable		 1wsvA-5k50A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kd5 METALLOPEPTIDASE

(Bacteroides
thetaiotaomicron) 		PF13402
(Peptidase_M60)
PF17291
(M60-like_N) 		3 ASP A 518
GLU A 478
TYR A 351
 None
 0.82A 1wsvA-5kd5A:
undetectable		 1wsvA-5kd5A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		3 ASP A 306
GLU A 492
TYR A 402
 TFB  A2003 ( 3.5A)
FAD  A2001 (-2.7A)
None
 0.73A 1wsvA-5kf7A:
undetectable		 1wsvA-5kf7A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqo NON-REDUCING END
BETA-L-ARABINOFURANO
SIDASE

(Bacteroides
thetaiotaomicron) 		PF07944
(Glyco_hydro_127) 		3 ASP A 346
GLU A 381
TYR A 336
 None
 0.82A 1wsvA-5mqoA:
undetectable		 1wsvA-5mqoA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ool 39S RIBOSOMAL
PROTEIN L37,
MITOCHONDRIAL
39S RIBOSOMAL
PROTEIN L41,
MITOCHONDRIAL
39S RIBOSOMAL
PROTEIN L24,
MITOCHONDRIAL

(Homo sapiens;
Homo sapiens;
Homo sapiens) 		PF07147
(PDCD9)
PF09809
(MRP-L27)
PF00467
(KOW)
PF17136
(ribosomal_L24) 		3 ASP 5  84
GLU 9  55
TYR V 210
 C  A1707 ( 4.6A)
None
None
 0.75A 1wsvA-5ool5:
undetectable		 1wsvA-5ool5:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sy5 ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
NEURONAL PAS
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus;
Mus musculus) 		PF00010
(HLH)
PF00989
(PAS)
PF14598
(PAS_11)
PF00010
(HLH)
PF00989
(PAS)
PF08447
(PAS_3) 		3 ASP A 161
GLU B 164
TYR B  94
 None
 0.84A 1wsvA-5sy5A:
undetectable		 1wsvA-5sy5A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t0h 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 2

(Homo sapiens) 		PF00004
(AAA) 		3 ASP f 393
GLU f 468
TYR f 441
 None
 0.86A 1wsvA-5t0hf:
undetectable		 1wsvA-5t0hf:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tlq THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA

(Pseudomonas
aeruginosa) 		PF01323
(DSBA) 		3 ASP A  89
GLU A  44
TYR A  35
 None
 0.69A 1wsvA-5tlqA:
undetectable		 1wsvA-5tlqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u3n DH511.12P FAB HEAVY
CHAIN
DH511.12P FAB LIGHT
CHAIN

(Homo sapiens;
Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		3 ASP H  53
GLU H  96
TYR L  96
 None
 0.77A 1wsvA-5u3nH:
undetectable		 1wsvA-5u3nH:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8f ORIGIN RECOGNITION
COMPLEX SUBUNIT 3
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		no annotation
PF13401
(AAA_22)
PF14630
(ORC5_C) 		3 ASP C 207
GLU E 426
TYR E 443
 None
 0.74A 1wsvA-5v8fC:
undetectable		 1wsvA-5v8fC:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wug BETA-GLUCOSIDASE

(Paenibacillus
barengoltzii) 		no annotation 3 ASP A 282
GLU A 410
TYR A 352
 None
 0.86A 1wsvA-5wugA:
undetectable		 1wsvA-5wugA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7u TREHALOSE SYNTHASE

(Thermobaculum
terrenum) 		no annotation 3 ASP A 202
GLU A 311
TYR A 373
 TRS  A 600 (-2.8A)
None
None
 0.78A 1wsvA-5x7uA:
undetectable		 1wsvA-5x7uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2z LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 3 ASP B 240
GLU B 383
TYR B 433
 None
 0.83A 1wsvA-5y2zB:
undetectable		 1wsvA-5y2zB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 3 ASP B 240
GLU B 383
TYR B 433
 None
 0.84A 1wsvA-5y31B:
undetectable		 1wsvA-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yj6 DOCKERIN TYPE I
REPEAT-CONTAINING
PROTEIN

(Ruminiclostridium
thermocellum) 		no annotation 3 ASP A 297
GLU A  87
TYR A 431
 None
None
33O  A 801 (-4.5A)
 0.68A 1wsvA-5yj6A:
undetectable		 1wsvA-5yj6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cnk IGG1 KAPPA LIGHT
CHAIN
IGG1 HEAVY CHAIN

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		3 ASP F   1
GLU G  51
TYR G 103
 None
 0.82A 1wsvA-6cnkF:
undetectable		 1wsvA-6cnkF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cza -

(-) 		no annotation 3 ASP A 561
GLU A 730
TYR A 809
 MGD  A 903 (-3.0A)
MGD  A 902 ( 4.1A)
MGD  A 903 (-4.1A)
 0.84A 1wsvA-6czaA:
undetectable		 1wsvA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoq DIPEPTIDYL PEPTIDASE
9

(Homo sapiens) 		no annotation 3 ASP A 251
GLU A 690
TYR A 644
 None
 0.81A 1wsvA-6eoqA:
undetectable		 1wsvA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eyu BACTERIORHODOPSIN

(Candidatus
Nanosalina sp.
J07AB43) 		no annotation 3 ASP A 102
GLU A 154
TYR A 163
 MUN  A 311 ( 4.4A)
None
None
 0.82A 1wsvA-6eyuA:
undetectable		 1wsvA-6eyuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f0k POLYSULPHIDE
REDUCTASE NRFD
ACTD
ACTF

(Rhodothermus
marinus;
Rhodothermus
marinus;
Rhodothermus
marinus) 		no annotation
no annotation
no annotation 		3 ASP C 253
GLU D 122
TYR F 284
 None
 0.79A 1wsvA-6f0kC:
undetectable		 1wsvA-6f0kC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8z ALPHA-1,2-MANNOSIDAS
E, PUTATIVE

(Bacteroides
thetaiotaomicron) 		no annotation 3 ASP A 131
GLU A 117
TYR A 125
 None
 0.81A 1wsvA-6f8zA:
undetectable		 1wsvA-6f8zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 ASP B 409
GLU A1058
TYR A1066
 None
 0.75A 1wsvA-6f9nB:
undetectable		 1wsvA-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ged PRGB

(Enterococcus
faecalis) 		no annotation 3 ASP A 310
GLU A 455
TYR A 490
 None
NA  A 601 (-2.9A)
EDO  A 602 ( 4.8A)
 0.80A 1wsvA-6gedA:
undetectable		 1wsvA-6gedA:
undetectable