SIMILAR PATTERNS OF AMINO ACIDS FOR 1WRK_B_TFPB203_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cby DELTA-ENDOTOXIN CYTB

(Bacillus
thuringiensis) 		PF01338
(Bac_thur_toxin) 		4 PHE A  75
LEU A 220
PHE A  43
SER A 174
 None
 1.28A 1wrkB-1cbyA:
undetectable		 1wrkB-1cbyA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl2 CLASS I
ALPHA-1,2-MANNOSIDAS
E

(Saccharomyces
cerevisiae) 		PF01532
(Glyco_hydro_47) 		4 PHE A 523
LEU A  93
PHE A 442
MET A 441
 None
 1.22A 1wrkB-1dl2A:
undetectable		 1wrkB-1dl2A:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 PHE A1098
LEU A1048
PHE A1139
MET A1224
 None
 1.08A 1wrkB-1foeA:
undetectable		 1wrkB-1foeA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1foe T-LYMPHOMA INVASION
AND METASTASIS
INDUCING PROTEIN 1

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 PHE A1294
PHE A1296
MET A1264
SER A1143
 None
 1.29A 1wrkB-1foeA:
undetectable		 1wrkB-1foeA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ka8 PUTATIVE P4-SPECIFIC
DNA PRIMASE

(Enterobacteria
phage P4) 		PF03288
(Pox_D5) 		4 PHE A   8
LEU A  89
PHE A  59
MET A  23
 None
 1.33A 1wrkB-1ka8A:
undetectable		 1wrkB-1ka8A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lwh 4-ALPHA-GLUCANOTRANS
FERASE

(Thermotoga
maritima) 		PF00128
(Alpha-amylase)
PF09178
(DUF1945) 		4 PHE A 205
LEU A  90
PHE A 201
MET A 191
 None
 0.92A 1wrkB-1lwhA:
undetectable		 1wrkB-1lwhA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1njk HYPOTHETICAL PROTEIN
YBAW

(Escherichia
coli) 		PF13279
(4HBT_2) 		4 PHE A 106
LEU A  76
MET A  44
SER A  40
 None
 1.24A 1wrkB-1njkA:
undetectable		 1wrkB-1njkA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nty TRIPLE FUNCTIONAL
DOMAIN PROTEIN

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 PHE A1296
LEU A1241
PHE A1321
MET A1398
 None
 0.97A 1wrkB-1ntyA:
undetectable		 1wrkB-1ntyA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ti8 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 PHE A 245
LEU A 235
PHE A 125
MET A 123
 None
 1.22A 1wrkB-1ti8A:
undetectable		 1wrkB-1ti8A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5k MICROTUBULE-ASSOCIAT
ED PROTEIN, RP/EB
FAMILY, MEMBER 1

(Mus musculus) 		PF00307
(CH) 		4 PHE A 108
LEU A  21
PHE A 104
SER A  33
 None
 1.22A 1wrkB-1v5kA:
undetectable		 1wrkB-1v5kA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wgp PROBABLE CYCLIC
NUCLEOTIDE-GATED ION
CHANNEL 6

(Arabidopsis
thaliana) 		PF00027
(cNMP_binding) 		4 PHE A  52
LEU A  86
PHE A  14
MET A  17
 None
 1.24A 1wrkB-1wgpA:
undetectable		 1wrkB-1wgpA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdz METHYLTRANSFERASE
GIDB

(Bacillus
subtilis) 		PF02527
(GidB) 		4 PHE A  55
LEU A 116
PHE A   6
SER A  18
 None
 1.17A 1wrkB-1xdzA:
0.0		 1wrkB-1xdzA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yoc HYPOTHETICAL PROTEIN
PA1835

(Pseudomonas
aeruginosa) 		PF14539
(DUF4442) 		4 PHE A  34
PHE A  16
MET A   4
SER A   2
 None
 1.24A 1wrkB-1yocA:
undetectable		 1wrkB-1yocA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2acv TRITERPENE
UDP-GLUCOSYL
TRANSFERASE UGT71G1

(Medicago
truncatula) 		PF00201
(UDPGT) 		4 PHE A  29
LEU A 457
PHE A  14
SER A  10
 None
 1.28A 1wrkB-2acvA:
undetectable		 1wrkB-2acvA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayu NUCLEOSOME ASSEMBLY
PROTEIN

(Saccharomyces
cerevisiae) 		PF00956
(NAP) 		4 PHE A 233
LEU A 193
PHE A 316
SER A 311
 None
 1.25A 1wrkB-2ayuA:
undetectable		 1wrkB-2ayuA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0d 2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE

(Pseudomonas
fluorescens) 		PF00561
(Abhydrolase_1) 		4 PHE A 104
PHE A 191
MET A 190
SER A 186
 None
 1.04A 1wrkB-2d0dA:
0.2		 1wrkB-2d0dA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4y FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 1

(Salmonella
enterica) 		no annotation 4 PHE A 308
LEU A 132
PHE A 304
SER A 108
 None
 1.34A 1wrkB-2d4yA:
undetectable		 1wrkB-2d4yA:
14.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2d58 ALLOGRAFT
INFLAMMATORY FACTOR
1

(Homo sapiens) 		no annotation 4 PHE A  57
LEU A  77
PHE A 106
MET A 110
 None
 1.17A 1wrkB-2d58A:
8.5		 1wrkB-2d58A:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2f2p CALMODULIN FUSED
WITH
CALMODULIN-BINDING
DOMAIN OF
CALCINEURIN

(Bos taurus) 		PF13499
(EF-hand_7) 		4 PHE A  19
LEU A  39
PHE A  68
MET A  72
 None
 1.02A 1wrkB-2f2pA:
11.5		 1wrkB-2f2pA:
61.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7c BETA-GLUCOSIDASE A

(Thermotoga
maritima) 		PF00232
(Glyco_hydro_1) 		4 PHE A 267
LEU A 176
PHE A 241
MET A 242
 None
 1.11A 1wrkB-2j7cA:
undetectable		 1wrkB-2j7cA:
11.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2k7d CALCIUM-BINDING
PROTEIN 1

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 PHE A 111
LEU A 131
PHE A 161
MET A 165
 None
 1.34A 1wrkB-2k7dA:
9.1		 1wrkB-2k7dA:
39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ptm HYPERPOLARIZATION-AC
TIVATED (IH) CHANNEL

(Strongylocentrotus
purpuratus) 		PF00027
(cNMP_binding) 		4 PHE A 545
PHE A 584
MET A 582
SER A 636
 None
 1.32A 1wrkB-2ptmA:
undetectable		 1wrkB-2ptmA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qw8 EUGENOL SYNTHASE 1

(Ocimum
basilicum) 		PF05368
(NmrA) 		4 PHE A 125
LEU A 265
PHE A  85
SER A 311
 NO3  A 902 (-4.9A)
None
NAP  A 401 ( 3.5A)
None
 1.37A 1wrkB-2qw8A:
undetectable		 1wrkB-2qw8A:
14.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rob CALMODULIN

(Glycine max) 		PF13499
(EF-hand_7) 		4 PHE A  92
LEU A 112
PHE A 141
MET A 145
 None
 1.04A 1wrkB-2robA:
11.3		 1wrkB-2robA:
40.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uy1 CLEAVAGE STIMULATION
FACTOR 77

(Encephalitozoon
cuniculi) 		PF05843
(Suf) 		4 PHE A 327
LEU A 449
PHE A 343
SER A 353
 None
 0.92A 1wrkB-2uy1A:
undetectable		 1wrkB-2uy1A:
10.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w49 TROPONIN C, SKELETAL
MUSCLE

(Gallus gallus) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		4 PHE 0  28
LEU 0  48
PHE 0  77
MET 0  81
 None
 0.85A 1wrkB-2w490:
13.0		 1wrkB-2w490:
64.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y0n MALE-SPECIFIC LETHAL
1 HOMOLOG
MALE-SPECIFIC LETHAL
3 HOMOLOG

(Homo sapiens;
Mus musculus) 		PF05712
(MRG)
no annotation 		4 PHE E 577
LEU A 459
PHE A 472
MET A 470
 None
 1.33A 1wrkB-2y0nE:
undetectable		 1wrkB-2y0nE:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1u HYDROGENASE
EXPRESSION/FORMATION
PROTEIN HYPE

(Desulfovibrio
vulgaris) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 PHE A  25
LEU A  96
PHE A  29
MET A 112
 None
 1.28A 1wrkB-2z1uA:
undetectable		 1wrkB-2z1uA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z2r NUCLEOSOME ASSEMBLY
PROTEIN

(Saccharomyces
cerevisiae) 		PF00956
(NAP) 		4 PHE A 233
LEU A 193
PHE A 316
SER A 311
 None
 1.23A 1wrkB-2z2rA:
undetectable		 1wrkB-2z2rA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwa LEUCINE CARBOXYL
METHYLTRANSFERASE 2

(Saccharomyces
cerevisiae) 		PF04072
(LCM)
PF13418
(Kelch_4) 		4 PHE A 339
LEU A 253
PHE A 336
SER A 315
 None
 1.12A 1wrkB-2zwaA:
undetectable		 1wrkB-2zwaA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afb PUTATIVE CHITINASE

(Pyrococcus
furiosus) 		no annotation 4 PHE A 523
LEU A 505
PHE A 552
MET A 572
 None
 1.15A 1wrkB-3afbA:
undetectable		 1wrkB-3afbA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2d CD180 ANTIGEN

(Homo sapiens) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 PHE A 180
LEU A 140
PHE A 206
SER A 189
 None
 1.07A 1wrkB-3b2dA:
undetectable		 1wrkB-3b2dA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0r C3-DEGRADING
PROTEINASE (CPPA
PROTEIN)

(Streptococcus
pneumoniae) 		PF14506
(CppA_N)
PF14507
(CppA_C) 		4 PHE A 238
LEU A 164
PHE A 226
SER A 214
 None
 1.23A 1wrkB-3e0rA:
undetectable		 1wrkB-3e0rA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e57 UNCHARACTERIZED
PROTEIN TM1382

(Thermotoga
maritima) 		PF00293
(NUDIX) 		4 PHE A  32
LEU A 144
PHE A 128
SER A 187
 None
 1.35A 1wrkB-3e57A:
undetectable		 1wrkB-3e57A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fs3 NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE

(Plasmodium
falciparum) 		PF00956
(NAP) 		4 PHE A 150
LEU A 107
PHE A 229
SER A 224
 None
 1.33A 1wrkB-3fs3A:
undetectable		 1wrkB-3fs3A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1n E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A4132
PHE A4081
MET A4073
SER A4070
 None
 1.14A 1wrkB-3g1nA:
undetectable		 1wrkB-3g1nA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyw NUCLEOSOME ASSEMBLY
PROTEIN 1, PUTATIVE

(Plasmodium
falciparum) 		PF00956
(NAP) 		4 PHE A 150
LEU A 107
PHE A 229
SER A 224
 None
 1.37A 1wrkB-3gywA:
undetectable		 1wrkB-3gywA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0r ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Aquifex
aeolicus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 PHE B  78
LEU B 101
PHE B  24
MET B  23
 None
 1.26A 1wrkB-3h0rB:
undetectable		 1wrkB-3h0rB:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hol TBPB

(Actinobacillus
pleuropneumoniae) 		PF01298
(TbpB_B_D)
PF17483
(TbpB_C)
PF17484
(TbpB_A) 		4 PHE A 194
LEU A 207
PHE A 226
SER A 252
 None
 1.19A 1wrkB-3holA:
undetectable		 1wrkB-3holA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwk METHYLCITRATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF00285
(Citrate_synt) 		4 PHE A 333
PHE A 279
MET A 321
SER A 323
 None
 1.36A 1wrkB-3hwkA:
undetectable		 1wrkB-3hwkA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		4 PHE A 494
LEU A 440
MET A 547
SER A 432
 None
 1.35A 1wrkB-3i04A:
undetectable		 1wrkB-3i04A:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iz3 VIRAL STRUCTURAL
PROTEIN 5

(Cypovirus 1) 		no annotation 4 PHE D 179
LEU D 252
PHE D  31
MET D 226
 None
 1.15A 1wrkB-3iz3D:
undetectable		 1wrkB-3iz3D:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermus
thermophilus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 PHE F  76
LEU F  99
PHE F  21
MET F  20
 None
 1.29A 1wrkB-3kfuF:
undetectable		 1wrkB-3kfuF:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m5h HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 PHE A 245
LEU A 235
PHE A 125
MET A 123
 None
 1.37A 1wrkB-3m5hA:
undetectable		 1wrkB-3m5hA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntl ACID
GLUCOSE-1-PHOSPHATE
PHOSPHATASE

(Enterobacter
cloacae) 		PF00328
(His_Phos_2) 		4 PHE A 320
LEU A 295
PHE A 380
MET A 384
 None
 1.37A 1wrkB-3ntlA:
undetectable		 1wrkB-3ntlA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5a DIHEME CYTOCHROME C
NAPB
PERIPLASMIC NITRATE
REDUCTASE

(Cupriavidus
necator) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF03892
(NapB)
PF04879
(Molybdop_Fe4S4) 		4 PHE A 715
LEU B  21
PHE A 769
SER A 772
 None
 1.14A 1wrkB-3o5aA:
undetectable		 1wrkB-3o5aA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozq SERPIN48

(Tenebrio
molitor) 		PF00079
(Serpin) 		4 PHE A  24
LEU A  94
PHE A  79
SER A  63
 None
 1.30A 1wrkB-3ozqA:
undetectable		 1wrkB-3ozqA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psi TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14635
(HHH_7)
PF14639
(YqgF)
PF14641
(HTH_44)
PF14878
(DLD) 		4 PHE A 962
LEU A 973
PHE A 954
SER A 932
 None
 1.37A 1wrkB-3psiA:
undetectable		 1wrkB-3psiA:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pt7 HEMOGLOBIN II

(Phacoides
pectinatus) 		PF00042
(Globin) 		4 LEU A 143
PHE A  69
MET A  73
SER A  75
 None
HEM  A 500 ( 4.8A)
HEM  A 500 (-3.7A)
None
 1.22A 1wrkB-3pt7A:
undetectable		 1wrkB-3pt7A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q8y NUCLEOSIDE
DIPHOSPHATE KINASE

(Staphylococcus
aureus) 		PF00334
(NDK) 		4 PHE A 131
LEU A  32
PHE A   5
SER A  84
 None
 1.36A 1wrkB-3q8yA:
undetectable		 1wrkB-3q8yA:
18.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3qrx CENTRIN
MELITTIN

(Apis mellifera;
Chlamydomonas
reinhardtii) 		PF01372
(Melittin)
PF13499
(EF-hand_7) 		4 PHE A 110
LEU B   9
PHE A 159
MET A 163
 None
 1.32A 1wrkB-3qrxA:
11.8		 1wrkB-3qrxA:
42.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r11 ENZYME OF ENOLASE
SUPERFAMILY

(Francisella
philomiragia) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PHE A 353
LEU A 270
PHE A 355
SER A  33
 None
 1.26A 1wrkB-3r11A:
undetectable		 1wrkB-3r11A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjo ENDOPLASMIC
RETICULUM
AMINOPEPTIDASE 1

(Homo sapiens) 		PF11838
(ERAP1_C) 		4 PHE A 702
LEU A 664
PHE A 699
MET A 683
 None
 1.37A 1wrkB-3rjoA:
undetectable		 1wrkB-3rjoA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw8 DENN
DOMAIN-CONTAINING
PROTEIN 1B

(Homo sapiens) 		PF02141
(DENN)
PF03455
(dDENN)
PF03456
(uDENN) 		4 PHE A 319
LEU A 284
PHE A 341
SER A 346
 None
 1.35A 1wrkB-3tw8A:
undetectable		 1wrkB-3tw8A:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u0k RCAMP

(Entacmaea
quadricolor) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		4 PHE A 313
LEU A 333
PHE A 362
MET A 366
 None
 1.13A 1wrkB-3u0kA:
10.1		 1wrkB-3u0kA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvq GLUTAMATE-PYRUVATE
AMINOTRANSFERASE
ALAA

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 PHE A 205
LEU A 231
PHE A 235
MET A 252
 None
 1.08A 1wrkB-4cvqA:
undetectable		 1wrkB-4cvqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d47 LEVANSUCRASE

(Erwinia
amylovora) 		PF02435
(Glyco_hydro_68) 		4 PHE A 207
LEU A 259
PHE A 293
SER A 324
 None
 1.03A 1wrkB-4d47A:
undetectable		 1wrkB-4d47A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eco UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		no annotation 4 PHE A 716
LEU A 763
PHE A 721
SER A 705
 None
 1.33A 1wrkB-4ecoA:
undetectable		 1wrkB-4ecoA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eei ADENYLOSUCCINATE
LYASE

(Francisella
tularensis) 		PF00206
(Lyase_1) 		4 PHE A 359
PHE A 355
MET A 409
SER A 387
 None
 1.28A 1wrkB-4eeiA:
undetectable		 1wrkB-4eeiA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw6 HYPOTHETICAL
PROTEIN, IPT/TIG
DOMAIN PROTEIN

(Bacteroides
ovatus) 		PF01833
(TIG) 		4 PHE A 201
LEU A 147
PHE A 178
SER A 438
 None
 1.32A 1wrkB-4hw6A:
undetectable		 1wrkB-4hw6A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2y RGECO1

(Discosoma sp.;
Gallus gallus;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		4 PHE A 395
LEU A 415
PHE A 444
MET A 448
 None
 1.35A 1wrkB-4i2yA:
11.0		 1wrkB-4i2yA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iik ADENOSINE
MONOPHOSPHATE-PROTEI
N HYDROLASE SIDD

(Legionella
pneumophila) 		no annotation 4 PHE A 123
LEU A 131
PHE A 169
MET A 171
 None
 1.17A 1wrkB-4iikA:
undetectable		 1wrkB-4iikA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iuw NEUTRAL
ENDOPEPTIDASE

(Lactobacillus
rhamnosus) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		4 PHE A 232
LEU A 115
PHE A 416
SER A 408
 None
 1.31A 1wrkB-4iuwA:
undetectable		 1wrkB-4iuwA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ivi CARBOXYLESTERASE

(uncultured
bacterium) 		PF00144
(Beta-lactamase) 		4 LEU A 245
PHE A 256
MET A 298
SER A 300
 None
 1.15A 1wrkB-4iviA:
undetectable		 1wrkB-4iviA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m69 MIXED LINEAGE KINASE
DOMAIN-LIKE PROTEIN

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		4 PHE B 385
LEU B 450
PHE B 324
SER B 248
 None
 1.35A 1wrkB-4m69B:
undetectable		 1wrkB-4m69B:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mk0 BETA-ADRENERGIC
RECEPTOR KINASE 1

(Homo sapiens) 		PF00069
(Pkinase)
PF00169
(PH)
PF00615
(RGS) 		4 PHE A 171
LEU A  47
PHE A 165
SER A  60
 None
 1.25A 1wrkB-4mk0A:
undetectable		 1wrkB-4mk0A:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN

(Pseudomonas
aeruginosa) 		PF03480
(DctP) 		4 PHE A 122
LEU A 131
PHE A 113
SER A  95
 None
 1.29A 1wrkB-4nf0A:
undetectable		 1wrkB-4nf0A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o3x TRANSFERRIN BINDING
PROTEIN B

(Actinobacillus
pleuropneumoniae) 		PF01298
(TbpB_B_D)
PF17484
(TbpB_A) 		4 PHE B 194
LEU B 207
PHE B 226
SER B 252
 None
 1.12A 1wrkB-4o3xB:
undetectable		 1wrkB-4o3xB:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o4x TBPB

(Glaesserella
parasuis) 		PF01298
(TbpB_B_D)
PF17483
(TbpB_C)
PF17484
(TbpB_A) 		4 PHE A 199
LEU A 212
PHE A 231
SER A 257
 None
 1.21A 1wrkB-4o4xA:
undetectable		 1wrkB-4o4xA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6t GLYCOSYL HYDROLASE,
FAMILY 18

(Pseudomonas
protegens) 		PF00704
(Glyco_hydro_18) 		4 PHE A 162
LEU A 132
PHE A 159
SER A 180
 None
 1.23A 1wrkB-4q6tA:
undetectable		 1wrkB-4q6tA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s1t URIDYLATE-SPECIFIC
ENDORIBONUCLEASE

(Human
coronavirus
229E) 		PF06471
(NSP11) 		4 PHE A 233
LEU A 251
PHE A 222
MET A 210
 None
 1.24A 1wrkB-4s1tA:
undetectable		 1wrkB-4s1tA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udb MINERALOCORTICOID
RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 PHE A 829
LEU A 938
PHE A 835
MET A 840
 CV7  A1987 (-4.9A)
CV7  A1987 ( 3.9A)
None
CV7  A1987 ( 3.7A)
 1.36A 1wrkB-4udbA:
undetectable		 1wrkB-4udbA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wlh KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 1

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 PHE A 347
LEU A 422
PHE A 366
MET A 370
 None
 1.10A 1wrkB-4wlhA:
undetectable		 1wrkB-4wlhA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wp0 KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 1

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 PHE A 347
LEU A 422
PHE A 366
MET A 370
 None
 1.17A 1wrkB-4wp0A:
undetectable		 1wrkB-4wp0A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztc AMINOTRANSFERASE
HOMOLOG

(Campylobacter
jejuni) 		PF01041
(DegT_DnrJ_EryC1) 		4 PHE A 267
LEU A 317
PHE A 269
SER A 364
 None
 1.29A 1wrkB-4ztcA:
undetectable		 1wrkB-4ztcA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a53 RIBOSOME BIOGENESIS
PROTEIN RPF2

(Saccharomyces
cerevisiae) 		PF04427
(Brix) 		4 PHE C 102
LEU C 230
MET C  90
SER C  92
 None
 1.35A 1wrkB-5a53C:
undetectable		 1wrkB-5a53C:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5buv PUTATIVE EPIMERASE

(Yersinia
enterocolitica) 		PF00908
(dTDP_sugar_isom) 		4 PHE A 154
LEU A  83
PHE A 152
MET A  62
 None
 1.26A 1wrkB-5buvA:
undetectable		 1wrkB-5buvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eaw DNA REPLICATION
ATP-DEPENDENT
HELICASE/NUCLEASE
DNA2

(Mus musculus) 		PF08696
(Dna2)
PF13086
(AAA_11)
PF13087
(AAA_12) 		4 PHE A 167
LEU A 298
PHE A 175
MET A 226
 None
 1.32A 1wrkB-5eawA:
undetectable		 1wrkB-5eawA:
6.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fi0 PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1
PROTEIN,PHOSPHATIDYL
INOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1 PROTEIN

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 PHE A 113
LEU A 131
PHE A 142
MET A 230
 None
 1.31A 1wrkB-5fi0A:
undetectable		 1wrkB-5fi0A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fms INTRAFLAGELLAR
TRANSPORT PROTEIN 52
HOMOLOG

(Mus musculus) 		PF09822
(ABC_transp_aux) 		4 PHE A 238
LEU A 225
MET A  86
SER A 216
 None
 1.13A 1wrkB-5fmsA:
undetectable		 1wrkB-5fmsA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5got LOW MOLECULAR WEIGHT
PHOSPHOTYROSINE
PHOSPHATASE FAMILY
PROTEIN

(Streptococcus
pyogenes) 		PF01451
(LMWPc) 		4 PHE A 108
PHE A   6
MET A  22
SER A  24
 None
 1.25A 1wrkB-5gotA:
undetectable		 1wrkB-5gotA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqf LACTO-N-BIOSIDASE

(Bifidobacterium
longum) 		no annotation 4 PHE A 498
LEU A 465
PHE A 503
SER A 485
 None
 1.32A 1wrkB-5gqfA:
undetectable		 1wrkB-5gqfA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hl3 LMO2470 PROTEIN

(Listeria
monocytogenes) 		PF00560
(LRR_1)
PF12354
(Internalin_N)
PF13855
(LRR_8) 		4 PHE A 215
LEU A 209
PHE A 193
SER A 165
 None
 1.34A 1wrkB-5hl3A:
undetectable		 1wrkB-5hl3A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idi 1,4-BETA-D-GLUCAN
GLUCOHYDROLASE

(Thermotoga
neapolitana) 		PF00232
(Glyco_hydro_1) 		4 PHE A 265
LEU A 174
PHE A 239
MET A 240
 None
 0.98A 1wrkB-5idiA:
undetectable		 1wrkB-5idiA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lp8 E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		no annotation 4 PHE B4132
PHE B4081
MET B4073
SER B4070
 None
 1.37A 1wrkB-5lp8B:
undetectable		 1wrkB-5lp8B:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m28 MALE1

(Lactobacillus
casei) 		PF13416
(SBP_bac_8) 		4 PHE A 352
LEU A 171
PHE A 380
SER A 192
 None
 1.15A 1wrkB-5m28A:
undetectable		 1wrkB-5m28A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n28 METHYL-COENZYME M
REDUCTASE SUBUNIT
ALPHA

(Methanotorris
formicicus) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		4 PHE A 100
LEU A 289
PHE A 531
SER A 339
 None
 1.10A 1wrkB-5n28A:
undetectable		 1wrkB-5n28A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfg PROCARDOSIN-B,PROCAR
DOSIN-B

(Cynara
cardunculus) 		no annotation 4 PHE A  79
LEU A  86
PHE A 218
MET A 189
 None
 1.34A 1wrkB-5nfgA:
undetectable		 1wrkB-5nfgA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nrm DOCCEL5: TYPE I
DOCKERIN REPEAT
DOMAIN FROM A.
CELLULOLYTICUS
FAMILY 5
ENDOGLUCANASE
WP_010249057 S51I,
L52N MUTANT
ENDOGLUCANASE

(Acetivibrio
cellulolyticus) 		no annotation 4 PHE B  55
LEU B  27
PHE B  19
SER A  34
 None
 1.37A 1wrkB-5nrmB:
undetectable		 1wrkB-5nrmB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o33 KALIRIN

(Rattus
norvegicus) 		PF00621
(RhoGEF) 		4 PHE B1296
LEU B1241
PHE B1321
MET B1398
 None
 0.98A 1wrkB-5o33B:
undetectable		 1wrkB-5o33B:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5of2 SPORE
COAT-ASSOCIATED
PROTEIN N

(Bacillus
subtilis) 		no annotation 4 LEU A 224
PHE A 228
MET A  85
SER A 142
 None
 1.24A 1wrkB-5of2A:
undetectable		 1wrkB-5of2A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t88 PROLYL ENDOPEPTIDASE

(Pyrococcus
furiosus) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 PHE A 399
PHE A 413
MET A 411
SER A 324
 None
 1.05A 1wrkB-5t88A:
undetectable		 1wrkB-5t88A:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4z REPRESSOR OF RNA
POLYMERASE III
TRANSCRIPTION

(Citrus sinensis) 		PF09174
(Maf1) 		4 PHE A 117
LEU A  16
PHE A 113
SER A 191
 None
 1.28A 1wrkB-5u4zA:
undetectable		 1wrkB-5u4zA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u6o POTASSIUM/SODIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 1

(Homo sapiens) 		PF00027
(cNMP_binding)
PF00520
(Ion_trans)
PF08412
(Ion_trans_N) 		4 PHE A 476
PHE A 514
MET A 512
SER A 565
 None
 1.18A 1wrkB-5u6oA:
undetectable		 1wrkB-5u6oA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuu BETA-ADRENERGIC
RECEPTOR KINASE 1

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		4 PHE A 171
LEU A  47
PHE A 165
SER A  60
 None
 1.19A 1wrkB-5uuuA:
undetectable		 1wrkB-5uuuA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v2d DIOXYGENASE

(Pseudomonas
brassicacearum) 		no annotation 4 LEU A 148
PHE A 468
MET A 470
SER A 473
 None
 1.34A 1wrkB-5v2dA:
undetectable		 1wrkB-5v2dA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7d ACYLOXYACYL
HYDROLASE

(Mus musculus) 		no annotation 4 PHE A 446
LEU A  41
PHE A 447
SER A 377
 PX8  A 610 ( 4.2A)
PX8  A 610 ( 4.5A)
None
None
 1.33A 1wrkB-5w7dA:
undetectable		 1wrkB-5w7dA:
17.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w88 TROPONIN C, TROPONIN
I

(Homo sapiens) 		PF00992
(Troponin)
PF13833
(EF-hand_8) 		4 PHE A  27
LEU A  48
PHE A  77
MET A  81
 9XG  A 201 (-3.8A)
9XG  A 201 ( 4.8A)
9XG  A 201 (-3.8A)
9XG  A 201 ( 4.6A)
 1.17A 1wrkB-5w88A:
11.5		 1wrkB-5w88A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ao8 ARGININE--TRNA
LIGASE

(Neisseria
gonorrhoeae) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 PHE A 499
LEU A 519
PHE A 148
SER A 141
 None
 1.34A 1wrkB-6ao8A:
undetectable		 1wrkB-6ao8A:
10.18