SIMILAR PATTERNS OF AMINO ACIDS FOR 1W5U_D_DVAD6_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2leq	UNCHARACTERIZED PROTEIN (Cytophaga hutchinsonii)	PF08327 (AHSA1)	4	TRP A 21 TRP A 43 ALA A 23 VAL A 25	None	1.40A	1w5uC-2leqA: undetectable 1w5uD-2leqA: undetectable	1w5uC-2leqA: 8.20 1w5uD-2leqA: 8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3a0h	PHOTOSYSTEM II D2 PROTEIN (Thermosynechococcus vulcanus)	PF00124 (Photo_RC)	4	TRP D 48 TRP D 111 ALA D 177 VAL D 78	PHO D1039 ( 3.5A) None None None	1.50A	1w5uC-3a0hD: undetectable 1w5uD-3a0hD: undetectable	1w5uC-3a0hD: 4.00 1w5uD-3a0hD: 4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ewn	STRUCTURAL PROTEIN (Mamastrovirus 1)	PF03115 (Astro_capsid_N)	4	TRP A 351 TRP A 324 ALA A 376 VAL A 353	None	1.17A	1w5uC-5ewnA: undetectable 1w5uD-5ewnA: undetectable	1w5uC-5ewnA: 6.37 1w5uD-5ewnA: 6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ibv	CAPSID POLYPROTEIN VP90 (Mamastrovirus 1)	PF03115 (Astro_capsid_N)	4	TRP A 351 TRP A 324 ALA A 376 VAL A 353	None	1.22A	1w5uC-5ibvA: undetectable 1w5uD-5ibvA: undetectable	1w5uC-5ibvA: 6.86 1w5uD-5ibvA: 6.86

[["1W5U_D_DVAD6_0","2leq","Cytophaga hutchinsonii","UNCHARACTERIZED PROTEIN","PF08327(AHSA1)",4,"TRP A  21;TRP A  43;ALA A  23;VAL A  25","None","1.40A","1w5uC-2leqA:undetectable;1w5uD-2leqA:undetectable","1w5uC-2leqA:8.20;1w5uD-2leqA:8.20"],["1W5U_D_DVAD6_0","3a0h","Thermosynechococcus vulcanus","PHOTOSYSTEM II D2 PROTEIN","PF00124(Photo_RC)",4,"TRP D  48;TRP D 111;ALA D 177;VAL D  78","PHO D1039 ( 3.5A);None;None;None","1.50A","1w5uC-3a0hD:undetectable;1w5uD-3a0hD:undetectable","1w5uC-3a0hD:4.00;1w5uD-3a0hD:4.00"],["1W5U_D_DVAD6_0","5ewn","Mamastrovirus 1","STRUCTURAL PROTEIN","PF03115(Astro_capsid_N)",4,"TRP A 351;TRP A 324;ALA A 376;VAL A 353","None","1.17A","1w5uC-5ewnA:undetectable;1w5uD-5ewnA:undetectable","1w5uC-5ewnA:6.37;1w5uD-5ewnA:6.37"],["1W5U_D_DVAD6_0","5ibv","Mamastrovirus 1","CAPSID POLYPROTEIN VP90","PF03115(Astro_capsid_N)",4,"TRP A 351;TRP A 324;ALA A 376;VAL A 353","None","1.22A","1w5uC-5ibvA:undetectable;1w5uD-5ibvA:undetectable","1w5uC-5ibvA:6.86;1w5uD-5ibvA:6.86"]]