SIMILAR PATTERNS OF AMINO ACIDS FOR 1W5U_B_DVAB6_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bqy | PLASMINOGENACTIVATOR (Trimeresurusstejnegeri) |
PF00089(Trypsin) | 3 | TRP A 215ALA A 55VAL A 99 | NoneNone0GJ A 1 ( 4.2A) | 0.76A | 1w5uA-1bqyA:undetectable1w5uB-1bqyA:undetectable | 1w5uA-1bqyA:7.011w5uB-1bqyA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d6m | DNA TOPOISOMERASEIII (Escherichiacoli) |
PF01131(Topoisom_bac)PF01751(Toprim) | 3 | TRP A 240ALA A 238VAL A 224 | None | 0.90A | 1w5uA-1d6mA:undetectable1w5uB-1d6mA:undetectable | 1w5uA-1d6mA:3.411w5uB-1d6mA:3.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fon | PROCARBOXYPEPTIDASEA-S6 (Bos taurus) |
PF00089(Trypsin) | 3 | TRP A 12ALA A 112VAL A 109 | None | 0.97A | 1w5uA-1fonA:undetectable1w5uB-1fonA:undetectable | 1w5uA-1fonA:6.101w5uB-1fonA:6.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkt | HEAT-SHOCKTRANSCRIPTION FACTOR (Drosophilamelanogaster) |
PF00447(HSF_DNA-bind) | 3 | TRP A 68ALA A 60VAL A 57 | None | 0.97A | 1w5uA-1hktA:undetectable1w5uB-1hktA:undetectable | 1w5uA-1hktA:17.021w5uB-1hktA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hzv | NITRITE REDUCTASE (Pseudomonasaeruginosa) |
PF02239(Cytochrom_D1)PF13442(Cytochrome_CBB3) | 3 | TRP A 246ALA A 48VAL A 53 | None | 0.91A | 1w5uA-1hzvA:undetectable1w5uB-1hzvA:undetectable | 1w5uA-1hzvA:4.441w5uB-1hzvA:4.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ile | ISOLEUCYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00133(tRNA-synt_1)PF08264(Anticodon_1) | 3 | TRP A 679ALA A 797VAL A 799 | None | 1.00A | 1w5uA-1ileA:undetectable1w5uB-1ileA:undetectable | 1w5uA-1ileA:1.971w5uB-1ileA:1.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j5s | URONATE ISOMERASE (Thermotogamaritima) |
PF02614(UxaC) | 3 | TRP A 44ALA A 53VAL A 50 | None | 0.97A | 1w5uA-1j5sA:undetectable1w5uB-1j5sA:undetectable | 1w5uA-1j5sA:5.241w5uB-1j5sA:5.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfw | CHITINASE B (Arthrobactersp. TAD20) |
PF00704(Glyco_hydro_18) | 3 | TRP A 378ALA A 335VAL A 338 | None | 0.85A | 1w5uA-1kfwA:undetectable1w5uB-1kfwA:undetectable | 1w5uA-1kfwA:3.191w5uB-1kfwA:3.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l1l | RIBONUCLEOSIDETRIPHOSPHATEREDUCTASE (Lactobacillusleichmannii) |
PF02867(Ribonuc_red_lgC) | 3 | TRP A 120ALA A 321VAL A 163 | None | 0.96A | 1w5uA-1l1lA:undetectable1w5uB-1l1lA:undetectable | 1w5uA-1l1lA:2.701w5uB-1l1lA:2.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l1l | RIBONUCLEOSIDETRIPHOSPHATEREDUCTASE (Lactobacillusleichmannii) |
PF02867(Ribonuc_red_lgC) | 3 | TRP A 642ALA A 646VAL A 547 | None | 0.92A | 1w5uA-1l1lA:undetectable1w5uB-1l1lA:undetectable | 1w5uA-1l1lA:2.701w5uB-1l1lA:2.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7u | ADSORPTION PROTEINP2 (Salmonellavirus PRD1) |
PF09214(Prd1-P2) | 3 | TRP A 501ALA A 499VAL A 6 | None | 0.99A | 1w5uA-1n7uA:undetectable1w5uB-1n7uA:undetectable | 1w5uA-1n7uA:2.711w5uB-1n7uA:2.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odo | PUTATIVE CYTOCHROMEP450 154A1 (Streptomycescoelicolor) |
PF00067(p450) | 3 | TRP A 81ALA A 184VAL A 174 | PIM A1408 (-4.6A)NoneNone | 0.74A | 1w5uA-1odoA:undetectable1w5uB-1odoA:undetectable | 1w5uA-1odoA:14.861w5uB-1odoA:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ppr | PERIDININ-CHLOROPHYLL PROTEIN (Amphidiniumcarterae) |
PF02429(PCP) | 3 | TRP M 186ALA M 238VAL M 241 | PID M 624 ( 3.6A)NonePID M 624 (-4.2A) | 0.90A | 1w5uA-1pprM:undetectable1w5uB-1pprM:undetectable | 1w5uA-1pprM:7.101w5uB-1pprM:7.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qfc | PROTEIN (PURPLE ACIDPHOSPHATASE) (Rattusnorvegicus) |
PF00149(Metallophos) | 3 | TRP A 15ALA A 241VAL A 12 | None | 0.90A | 1w5uA-1qfcA:undetectable1w5uB-1qfcA:undetectable | 1w5uA-1qfcA:5.001w5uB-1qfcA:5.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhq | PROTEIN (AURACYANIN) (Chloroflexusaurantiacus) |
PF00127(Copper-bind) | 3 | TRP A 59ALA A 23VAL A 21 | None | 0.85A | 1w5uA-1qhqA:undetectable1w5uB-1qhqA:undetectable | 1w5uA-1qhqA:6.431w5uB-1qhqA:6.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rbl | RIBULOSE 1,5BISPHOSPHATECARBOXYLASE/OXYGENASE (LARGE CHAIN) (Synechococcuselongatus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | TRP A 70ALA A 15VAL A 69 | None | 0.90A | 1w5uA-1rblA:undetectable1w5uB-1rblA:undetectable | 1w5uA-1rblA:4.081w5uB-1rblA:4.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1to3 | PUTATIVE ALDOLASEYIHT (Salmonellaenterica) |
PF01791(DeoC) | 3 | TRP A 256ALA A 274VAL A 255 | None | 0.86A | 1w5uA-1to3A:undetectable1w5uB-1to3A:undetectable | 1w5uA-1to3A:6.401w5uB-1to3A:6.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5w | HYPOTHETICAL UPF0244PROTEIN YJJX (Escherichiacoli) |
PF01931(NTPase_I-T) | 3 | TRP A 75ALA A 77VAL A 8 | None | 0.92A | 1w5uA-1u5wA:undetectable1w5uB-1u5wA:undetectable | 1w5uA-1u5wA:6.181w5uB-1u5wA:6.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 3 | TRP A 365ALA A 174VAL A 369 | None | 0.83A | 1w5uA-1u7gA:undetectable1w5uB-1u7gA:undetectable | 1w5uA-1u7gA:5.191w5uB-1u7gA:5.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1up2 | CELA1 PROTEIN (Mycobacteriumtuberculosis) |
PF01341(Glyco_hydro_6) | 3 | TRP A 186ALA A 137VAL A 139 | None | 0.88A | 1w5uA-1up2A:undetectable1w5uB-1up2A:undetectable | 1w5uA-1up2A:6.251w5uB-1up2A:6.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y43 | ASPERGILLOPEPSIN IIHEAVY CHAIN (Aspergillusniger) |
PF01828(Peptidase_A4) | 3 | TRP B 107ALA B 9VAL B 11 | None | 0.47A | 1w5uA-1y43B:undetectable1w5uB-1y43B:undetectable | 1w5uA-1y43B:6.131w5uB-1y43B:6.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a7w | PHOSPHORIBOSYL-ATPPYROPHOSPHATASE (Chromobacteriumviolaceum) |
PF01503(PRA-PH) | 3 | TRP A 68ALA A 45VAL A 64 | None | 0.75A | 1w5uA-2a7wA:undetectable1w5uB-2a7wA:undetectable | 1w5uA-2a7wA:8.041w5uB-2a7wA:8.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2btd | PTS-DEPENDENTDIHYDROXYACETONEKINASE (Escherichiacoli) |
PF02734(Dak2) | 3 | TRP A 134ALA A 123VAL A 117 | NoneADP A1211 ( 4.4A)None | 0.92A | 1w5uA-2btdA:undetectable1w5uB-2btdA:undetectable | 1w5uA-2btdA:7.521w5uB-2btdA:7.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cwf | DELTA1-PIPERIDEINE-2-CARBOXYLATEREDUCTASE (Pseudomonassyringae groupgenomosp. 3) |
PF02615(Ldh_2) | 3 | TRP A 70ALA A 67VAL A 71 | None | 0.92A | 1w5uA-2cwfA:undetectable1w5uB-2cwfA:undetectable | 1w5uA-2cwfA:6.221w5uB-2cwfA:6.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3y | URACIL-DNAGLYCOSYLASE (Thermusthermophilus) |
PF03167(UDG) | 3 | TRP A 39ALA A 116VAL A 43 | None | 0.76A | 1w5uA-2d3yA:undetectable1w5uB-2d3yA:undetectable | 1w5uA-2d3yA:8.731w5uB-2d3yA:8.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4w | GLYCEROL KINASE (Cellulomonassp.) |
PF00370(FGGY_N)PF02782(FGGY_C) | 3 | TRP A 102ALA A 85VAL A 101 | MPD A 1 ( 3.9A)NoneNone | 0.88A | 1w5uA-2d4wA:undetectable1w5uB-2d4wA:undetectable | 1w5uA-2d4wA:4.981w5uB-2d4wA:4.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ffi | 2-PYRONE-4,6-DICARBOXYLIC ACIDHYDROLASE, PUTATIVE (Pseudomonasputida) |
PF04909(Amidohydro_2) | 3 | TRP A 233ALA A 215VAL A 198 | None | 0.97A | 1w5uA-2ffiA:undetectable1w5uB-2ffiA:undetectable | 1w5uA-2ffiA:5.681w5uB-2ffiA:5.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lpu | KMATG10 (Kluyveromycesmarxianus) |
PF03987(Autophagy_act_C) | 3 | TRP A 133ALA A 120VAL A 122 | None | 1.00A | 1w5uA-2lpuA:undetectable1w5uB-2lpuA:undetectable | 1w5uA-2lpuA:8.261w5uB-2lpuA:8.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk8 | CAI-1 AUTOINDUCERSYNTHASE (Vibrio cholerae) |
PF00155(Aminotran_1_2) | 3 | TRP A 109ALA A 111VAL A 113 | None | 0.99A | 1w5uA-2wk8A:undetectable1w5uB-2wk8A:undetectable | 1w5uA-2wk8A:5.561w5uB-2wk8A:5.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axx | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 3 | TRP A 323ALA A 271VAL A 298 | None | 0.78A | 1w5uA-3axxA:undetectable1w5uB-3axxA:undetectable | 1w5uA-3axxA:3.231w5uB-3axxA:3.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e2s | PROLINEDEHYDROGENASE (Escherichiacoli) |
PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | TRP A 438ALA A 405VAL A 455 | FAD A2001 (-3.6A)NoneNone | 0.84A | 1w5uA-3e2sA:undetectable1w5uB-3e2sA:undetectable | 1w5uA-3e2sA:1.861w5uB-3e2sA:1.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fsc | QDTC (Thermoanaerobacteriumthermosaccharolyticum) |
PF00132(Hexapep) | 3 | TRP A 239ALA A 195VAL A 178 | None | 0.98A | 1w5uA-3fscA:undetectable1w5uB-3fscA:undetectable | 1w5uA-3fscA:13.891w5uB-3fscA:13.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i2t | EPIDERMAL GROWTHFACTOR RECEPTOR,ISOFORM A (Drosophilamelanogaster) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 3 | TRP A 457ALA A 405VAL A 430 | None | 0.91A | 1w5uA-3i2tA:undetectable1w5uB-3i2tA:undetectable | 1w5uA-3i2tA:3.281w5uB-3i2tA:3.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3njb | ENOYL-COA HYDRATASE (Mycolicibacteriumsmegmatis) |
PF00378(ECH_1) | 3 | TRP A 177ALA A 281VAL A 283 | None | 0.84A | 1w5uA-3njbA:undetectable1w5uB-3njbA:undetectable | 1w5uA-3njbA:6.801w5uB-3njbA:6.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oft | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 3 | TRP A 61ALA A 342VAL A 340 | HEM A 417 (-4.1A)NoneNone | 0.46A | 1w5uA-3oftA:undetectable1w5uB-3oftA:undetectable | 1w5uA-3oftA:19.641w5uB-3oftA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oq3 | INTERFERON ALPHA-5 (Mus musculus) |
PF00143(Interferon) | 3 | TRP A 149ALA A 14VAL A 19 | None | 0.97A | 1w5uA-3oq3A:undetectable1w5uB-3oq3A:undetectable | 1w5uA-3oq3A:9.021w5uB-3oq3A:9.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usc | HYDROGENASE-1 LARGECHAIN (Escherichiacoli) |
PF00374(NiFeSe_Hases) | 3 | TRP L 515ALA L 517VAL L 502 | None | 0.93A | 1w5uA-3uscL:undetectable1w5uB-3uscL:undetectable | 1w5uA-3uscL:5.261w5uB-3uscL:5.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ut2 | CATALASE-PEROXIDASE2 (Magnaportheoryzae) |
PF00141(peroxidase) | 3 | TRP A 365ALA A 418VAL A 363 | None | 0.87A | 1w5uA-3ut2A:undetectable1w5uB-3ut2A:undetectable | 1w5uA-3ut2A:3.081w5uB-3ut2A:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w36 | NAPH1 (Streptomycessp. CNQ525) |
no annotation | 3 | TRP A 146ALA A 186VAL A 98 | None | 0.96A | 1w5uA-3w36A:undetectable1w5uB-3w36A:undetectable | 1w5uA-3w36A:4.621w5uB-3w36A:4.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w6m | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 3 | TRP A 323ALA A 271VAL A 298 | None | 0.77A | 1w5uA-3w6mA:undetectable1w5uB-3w6mA:undetectable | 1w5uA-3w6mA:3.531w5uB-3w6mA:3.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwe | OXIDIZED POLYVINYLALCOHOL HYDROLASE (Pseudomonas sp.VM15C) |
no annotation | 3 | TRP A 60ALA A 50VAL A 92 | None | 0.98A | 1w5uA-3wweA:undetectable1w5uB-3wweA:undetectable | 1w5uA-3wweA:4.601w5uB-3wweA:4.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akk | NITRATE REGULATORYPROTEIN (Klebsiellaoxytoca) |
PF03861(ANTAR)PF08376(NIT) | 3 | TRP A 56ALA A 124VAL A 118 | None | 0.95A | 1w5uA-4akkA:undetectable1w5uB-4akkA:undetectable | 1w5uA-4akkA:3.241w5uB-4akkA:3.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akk | NITRATE REGULATORYPROTEIN (Klebsiellaoxytoca) |
PF03861(ANTAR)PF08376(NIT) | 3 | TRP A 56ALA A 125VAL A 118 | None | 0.86A | 1w5uA-4akkA:undetectable1w5uB-4akkA:undetectable | 1w5uA-4akkA:3.241w5uB-4akkA:3.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cs6 | AMINOGLYCOSIDEADENYLTRANSFERASE (Salmonellaenterica) |
PF01909(NTP_transf_2)PF13427(DUF4111) | 3 | TRP A 173ALA A 177VAL A 179 | None | 0.99A | 1w5uA-4cs6A:undetectable1w5uB-4cs6A:undetectable | 1w5uA-4cs6A:8.551w5uB-4cs6A:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dcc | PUTATIVE HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacteroidesthetaiotaomicron) |
PF13419(HAD_2) | 3 | TRP A 200ALA A 196VAL A 16 | None | 0.97A | 1w5uA-4dccA:undetectable1w5uB-4dccA:undetectable | 1w5uA-4dccA:5.631w5uB-4dccA:5.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4di1 | ENOYL-COA HYDRATASEECHA17 (Mycobacteriummarinum) |
PF00378(ECH_1) | 3 | TRP A 192ALA A 49VAL A 98 | None | 0.86A | 1w5uA-4di1A:undetectable1w5uB-4di1A:undetectable | 1w5uA-4di1A:17.391w5uB-4di1A:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eb0 | LCC (unculturedbacterium) |
PF12695(Abhydrolase_5) | 3 | TRP A 259ALA A 160VAL A 185 | None | 1.00A | 1w5uA-4eb0A:undetectable1w5uB-4eb0A:undetectable | 1w5uA-4eb0A:16.671w5uB-4eb0A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4epa | PESTICIN RECEPTOR (Yersinia pestis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | TRP A 513ALA A 468VAL A 470 | None | 0.81A | 1w5uA-4epaA:undetectable1w5uB-4epaA:undetectable | 1w5uA-4epaA:2.151w5uB-4epaA:2.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fom | POLIOVIRUSRECEPTOR-RELATEDPROTEIN 3 (Homo sapiens) |
PF07686(V-set)PF08205(C2-set_2) | 3 | TRP A 70ALA A 68VAL A 168 | NAG A 415 ( 4.1A)NoneNAG A 415 ( 4.6A) | 0.93A | 1w5uA-4fomA:undetectable1w5uB-4fomA:undetectable | 1w5uA-4fomA:4.861w5uB-4fomA:4.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ftd | UNCHARACTERIZEDPROTEIN (Bacteroideseggerthii) |
PF15416(DUF4623) | 3 | TRP A 334ALA A 362VAL A 323 | None | 0.87A | 1w5uA-4ftdA:undetectable1w5uB-4ftdA:undetectable | 1w5uA-4ftdA:2.431w5uB-4ftdA:2.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hi4 | AEROTAXIS TRANSDUCERAER2 (Pseudomonasaeruginosa) |
PF13188(PAS_8) | 3 | TRP A 283ALA A 184VAL A 202 | None | 0.58A | 1w5uA-4hi4A:undetectable1w5uB-4hi4A:undetectable | 1w5uA-4hi4A:8.741w5uB-4hi4A:8.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i9r | CELLULAR RETINOICACID-BINDING PROTEIN2 (Homo sapiens) |
PF00061(Lipocalin) | 3 | TRP A 32ALA A 35VAL A 33 | RET A 201 (-4.5A)NoneNone | 0.93A | 1w5uA-4i9rA:undetectable1w5uB-4i9rA:undetectable | 1w5uA-4i9rA:10.481w5uB-4i9rA:10.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j4j | DNA DC->DU-EDITINGENZYME APOBEC-3F (Homo sapiens) |
PF08210(APOBEC_N) | 3 | TRP A 277ALA A 250VAL A 242 | None | 0.83A | 1w5uA-4j4jA:undetectable1w5uB-4j4jA:undetectable | 1w5uA-4j4jA:5.671w5uB-4j4jA:5.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jpq | UNCHARACTERIZEDPROTEIN (Bacteroidesuniformis) |
PF16011(CBM9_2) | 3 | TRP A 185ALA A 101VAL A 103 | None | 0.94A | 1w5uA-4jpqA:undetectable1w5uB-4jpqA:undetectable | 1w5uA-4jpqA:8.111w5uB-4jpqA:8.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2j | AMINOTRANSFERASE (Streptomyceslavendulae) |
PF00155(Aminotran_1_2) | 3 | TRP A 236ALA A 239VAL A 85 | None | 0.97A | 1w5uA-4m2jA:undetectable1w5uB-4m2jA:undetectable | 1w5uA-4m2jA:3.691w5uB-4m2jA:3.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7r | ANAMORSIN (Homo sapiens) |
PF08241(Methyltransf_11) | 3 | TRP A 40ALA A 37VAL A 68 | None | 0.93A | 1w5uA-4m7rA:undetectable1w5uB-4m7rA:undetectable | 1w5uA-4m7rA:9.911w5uB-4m7rA:9.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mkv | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Pisum sativum) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 3 | TRP A 70ALA A 15VAL A 69 | None | 0.85A | 1w5uA-4mkvA:undetectable1w5uB-4mkvA:undetectable | 1w5uA-4mkvA:3.791w5uB-4mkvA:3.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mpt | PUTATIVELEU/ILE/VAL-BINDINGPROTEIN (Bordetellapertussis) |
PF13458(Peripla_BP_6) | 3 | TRP A 285ALA A 298VAL A 301 | None | 0.94A | 1w5uA-4mptA:undetectable1w5uB-4mptA:undetectable | 1w5uA-4mptA:5.631w5uB-4mptA:5.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 3 | TRP A 310ALA A 277VAL A 326 | P5F A1101 (-3.6A)NoneNone | 0.76A | 1w5uA-4nmeA:undetectable1w5uB-4nmeA:undetectable | 1w5uA-4nmeA:2.231w5uB-4nmeA:2.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o8a | BIFUNCTIONAL PROTEINPUTA (Escherichiacoli) |
PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | TRP A 438ALA A 405VAL A 455 | FAD A2001 (-3.5A)NoneNone | 0.82A | 1w5uA-4o8aA:undetectable1w5uB-4o8aA:undetectable | 1w5uA-4o8aA:3.021w5uB-4o8aA:3.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4og1 | ENOYL-COAHYDRATASE/ISOMERASE (Novosphingobiumaromaticivorans) |
PF00378(ECH_1) | 3 | TRP A 103ALA A 154VAL A 125 | None | 0.93A | 1w5uA-4og1A:undetectable1w5uB-4og1A:undetectable | 1w5uA-4og1A:7.561w5uB-4og1A:7.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ojz | PUTATIVE ALGINATELYASE (Saccharophagusdegradans) |
PF05426(Alginate_lyase)PF07940(Hepar_II_III) | 3 | TRP A 47ALA A 41VAL A 105 | None | 0.94A | 1w5uA-4ojzA:undetectable1w5uB-4ojzA:undetectable | 1w5uA-4ojzA:3.591w5uB-4ojzA:3.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqr | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 3 | TRP A 48ALA A 290VAL A 308 | None | 0.93A | 1w5uA-4oqrA:undetectable1w5uB-4oqrA:undetectable | 1w5uA-4oqrA:3.201w5uB-4oqrA:3.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqs | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 3 | TRP A 48ALA A 290VAL A 308 | None | 0.93A | 1w5uA-4oqsA:undetectable1w5uB-4oqsA:undetectable | 1w5uA-4oqsA:3.201w5uB-4oqsA:3.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvi | GH62 HYDROLASE (Mycothermusthermophilus) |
PF03664(Glyco_hydro_62) | 3 | TRP A 34ALA A 288VAL A 290 | None | 0.74A | 1w5uA-4pviA:undetectable1w5uB-4pviA:undetectable | 1w5uA-4pviA:3.271w5uB-4pviA:3.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q73 | PROLINEDEHYDROGENASE (Bradyrhizobiumdiazoefficiens) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | TRP A 346ALA A 313VAL A 363 | FAD A2001 (-3.6A)NoneNone | 0.82A | 1w5uA-4q73A:undetectable1w5uB-4q73A:undetectable | 1w5uA-4q73A:2.581w5uB-4q73A:2.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9b | NOVEL ANTIGENRECEPTOR (Ginglymostomacirratum) |
PF07654(C1-set) | 3 | TRP A 258ALA A 263VAL A 254 | None | 0.97A | 1w5uA-4q9bA:undetectable1w5uB-4q9bA:undetectable | 1w5uA-4q9bA:10.391w5uB-4q9bA:10.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r12 | PUTATIVEUNCHARACTERIZEDPROTEIN (Dictyosteliumpurpureum) |
PF05450(Nicastrin) | 3 | TRP A 291ALA A 566VAL A 213 | None | 0.95A | 1w5uA-4r12A:undetectable1w5uB-4r12A:undetectable | 1w5uA-4r12A:2.431w5uB-4r12A:2.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tz5 | PUTATIVE SECRETEDPROTEIN (Streptomycessp. SirexAA-E) |
no annotation | 3 | TRP A 170ALA A 190VAL A 172 | None | 0.98A | 1w5uA-4tz5A:undetectable1w5uB-4tz5A:undetectable | 1w5uA-4tz5A:3.341w5uB-4tz5A:3.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zyo | ACYL-COA DESATURASE (Homo sapiens) |
no annotation | 3 | TRP A 123ALA A 207VAL A 211 | None | 1.00A | 1w5uA-4zyoA:undetectable1w5uB-4zyoA:undetectable | 1w5uA-4zyoA:4.471w5uB-4zyoA:4.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a7m | BETA-XYLOSIDASE (Trichodermareesei) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 3 | TRP A 501ALA A 578VAL A 529 | None | 0.63A | 1w5uA-5a7mA:undetectable1w5uB-5a7mA:undetectable | 1w5uA-5a7mA:1.951w5uB-5a7mA:1.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II SUBUNITALPHA (Methanothermobactermarburgensis) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 3 | TRP A 229ALA A 166VAL A 213 | None | 0.72A | 1w5uA-5a8rA:undetectable1w5uB-5a8rA:undetectable | 1w5uA-5a8rA:4.081w5uB-5a8rA:4.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aca | VP1 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 3 | TRP 1 89ALA 1 50VAL 1 173 | None | 0.96A | 1w5uA-5aca1:undetectable1w5uB-5aca1:undetectable | 1w5uA-5aca1:10.611w5uB-5aca1:10.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5afu | DYNACTIN (Sus scrofa) |
PF00022(Actin) | 3 | TRP J 387ALA J 121VAL J 95 | None | 0.98A | 1w5uA-5afuJ:undetectable1w5uB-5afuJ:undetectable | 1w5uA-5afuJ:2.931w5uB-5afuJ:2.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cju | ISOBUTYRYL-COAMUTASE FUSED (Cupriavidusmetallidurans) |
PF01642(MM_CoA_mutase)PF02310(B12-binding)PF03308(ArgK) | 3 | TRP A 368ALA A 355VAL A 391 | None | 0.85A | 1w5uA-5cjuA:undetectable1w5uB-5cjuA:undetectable | 1w5uA-5cjuA:2.131w5uB-5cjuA:2.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5clw | 1,4-ALPHA-GLUCAN-BRANCHING ENZYME (Homo sapiens) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 3 | TRP A 548ALA A 483VAL A 485 | None | 0.95A | 1w5uA-5clwA:undetectable1w5uB-5clwA:undetectable | 1w5uA-5clwA:2.521w5uB-5clwA:2.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7l | CONTACTIN-2 (Mus musculus) |
PF00041(fn3) | 3 | TRP A 835ALA A 819VAL A 821 | None | 1.00A | 1w5uA-5e7lA:undetectable1w5uB-5e7lA:undetectable | 1w5uA-5e7lA:10.671w5uB-5e7lA:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ebb | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3A (Homo sapiens) |
PF00149(Metallophos) | 3 | TRP A 107ALA A 318VAL A 43 | None | 0.99A | 1w5uA-5ebbA:undetectable1w5uB-5ebbA:undetectable | 1w5uA-5ebbA:3.981w5uB-5ebbA:3.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ewn | STRUCTURAL PROTEIN (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | TRP A 351ALA A 376VAL A 369 | None | 0.87A | 1w5uA-5ewnA:undetectable1w5uB-5ewnA:undetectable | 1w5uA-5ewnA:6.371w5uB-5ewnA:6.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fca | ACIDSPHINGOMYELINASE-LIKE PHOSPHODIESTERASE3A (Mus musculus) |
PF00149(Metallophos) | 3 | TRP A 104ALA A 315VAL A 40 | None | 1.00A | 1w5uA-5fcaA:undetectable1w5uB-5fcaA:undetectable | 1w5uA-5fcaA:5.501w5uB-5fcaA:5.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g06 | EXOSOME COMPLEXCOMPONENT RRP4 (Saccharomycescerevisiae) |
PF14382(ECR1_N)PF15985(KH_6) | 3 | TRP H 124ALA H 117VAL H 119 | None | 0.71A | 1w5uA-5g06H:undetectable1w5uB-5g06H:undetectable | 1w5uA-5g06H:4.711w5uB-5g06H:4.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzh | ENDO-BETA-1,2-GLUCANASE (Chitinophagapinensis) |
PF10091(Glycoamylase) | 3 | TRP A 120ALA A 52VAL A 69 | NoneNoneIOD A 506 ( 4.7A) | 1.00A | 1w5uA-5gzhA:undetectable1w5uB-5gzhA:undetectable | 1w5uA-5gzhA:3.111w5uB-5gzhA:3.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibv | CAPSID POLYPROTEINVP90 (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | TRP A 351ALA A 376VAL A 369 | None | 0.97A | 1w5uA-5ibvA:undetectable1w5uB-5ibvA:undetectable | 1w5uA-5ibvA:6.861w5uB-5ibvA:6.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf7 | BIFUNCTIONAL PROTEINPUTA (Sinorhizobiummeliloti) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 3 | TRP A 374ALA A 341VAL A 391 | FAD A2001 (-3.6A)NoneNone | 0.83A | 1w5uA-5kf7A:undetectable1w5uB-5kf7A:undetectable | 1w5uA-5kf7A:1.641w5uB-5kf7A:1.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 3 | TRP B 473ALA B 478VAL B 472 | None | 0.64A | 1w5uA-5kohB:undetectable1w5uB-5kohB:undetectable | 1w5uA-5kohB:3.101w5uB-5kohB:3.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lpe | KALLIKREIN-10 (Homo sapiens) |
PF00089(Trypsin) | 3 | TRP A 29ALA A 43VAL A 45 | None | 0.84A | 1w5uA-5lpeA:undetectable1w5uB-5lpeA:undetectable | 1w5uA-5lpeA:11.251w5uB-5lpeA:11.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanotorrisformicicus) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 3 | TRP A 229ALA A 166VAL A 213 | None | 0.69A | 1w5uA-5n28A:undetectable1w5uB-5n28A:undetectable | 1w5uA-5n28A:2.321w5uB-5n28A:2.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ndx | GLYCOSYL HYDROLASE (Rhizobiumleguminosarum) |
no annotation | 3 | TRP A 116ALA A 168VAL A 120 | None | 0.97A | 1w5uA-5ndxA:undetectable1w5uB-5ndxA:undetectable | 1w5uA-5ndxA:undetectable1w5uB-5ndxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o7g | ALPHA/BETA HYDROLASEFAMILY PROTEIN (Bacilluscoagulans) |
no annotation | 3 | TRP A 80ALA A 71VAL A 65 | None | 0.94A | 1w5uA-5o7gA:undetectable1w5uB-5o7gA:undetectable | 1w5uA-5o7gA:undetectable1w5uB-5o7gA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o82 | INTRACELLULAREXO-ALPHA-(1->5)-L-ARABINOFURANOSIDASE (Chaetomiumthermophilum) |
no annotation | 3 | TRP A 224ALA A 226VAL A 228 | None | 0.97A | 1w5uA-5o82A:undetectable1w5uB-5o82A:undetectable | 1w5uA-5o82A:undetectable1w5uB-5o82A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5okz | EXOSOME COMPLEXCOMPONENT RRP4 (Saccharomycescerevisiae) |
PF14382(ECR1_N)PF15985(KH_6) | 3 | TRP H 124ALA H 117VAL H 119 | None | 0.78A | 1w5uA-5okzH:undetectable1w5uB-5okzH:undetectable | 1w5uA-5okzH:5.081w5uB-5okzH:5.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sv0 | BIOPOLYMER TRANSPORTPROTEIN EXBB (Escherichiacoli) |
no annotation | 3 | TRP B 150ALA B 19VAL B 22 | None | 0.92A | 1w5uA-5sv0B:undetectable1w5uB-5sv0B:undetectable | 1w5uA-5sv0B:8.731w5uB-5sv0B:8.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tkm | DNA DC->DU-EDITINGENZYME APOBEC-3B (Homo sapiens) |
PF08210(APOBEC_N) | 3 | TRP A 94ALA A 67VAL A 59 | None | 0.80A | 1w5uA-5tkmA:undetectable1w5uB-5tkmA:undetectable | 1w5uA-5tkmA:6.541w5uB-5tkmA:6.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ui3 | DIHYDRODIPICOLINATESYNTHASE (Chlamydomonasreinhardtii) |
no annotation | 3 | TRP D 201ALA D 211VAL D 218 | None | 0.99A | 1w5uA-5ui3D:undetectable1w5uB-5ui3D:undetectable | 1w5uA-5ui3D:undetectable1w5uB-5ui3D:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uld | TRANSPORTER, NADCFAMILY (Vibrio cholerae) |
PF00939(Na_sulph_symp) | 3 | TRP A 59ALA A 63VAL A 66 | None | 0.71A | 1w5uA-5uldA:undetectable1w5uB-5uldA:undetectable | 1w5uA-5uldA:2.971w5uB-5uldA:2.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur2 | BIFUNCTIONAL PROTEINPUTA (Bdellovibriobacteriovorus) |
PF00171(Aldedh)PF01619(Pro_dh) | 3 | TRP A 305ALA A 272VAL A 321 | P5F A1001 (-3.7A)NoneNone | 0.84A | 1w5uA-5ur2A:undetectable1w5uB-5ur2A:undetectable | 1w5uA-5ur2A:2.821w5uB-5ur2A:2.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vf4 | UNCHARACTERIZEDPROTEIN (Thermusaquaticus) |
PF03781(FGE-sulfatase) | 3 | TRP A 201ALA A 90VAL A 373 | None | 0.83A | 1w5uA-5vf4A:undetectable1w5uB-5vf4A:undetectable | 1w5uA-5vf4A:6.061w5uB-5vf4A:6.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsx | CHITINASE (Thermococcuschitonophagus) |
no annotation | 3 | TRP A 682ALA A 646VAL A 680 | None | 0.87A | 1w5uA-5xsxA:undetectable1w5uB-5xsxA:undetectable | 1w5uA-5xsxA:undetectable1w5uB-5xsxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yim | SDEA (Legionellapneumophila) |
no annotation | 3 | TRP A 394ALA A 399VAL A 401 | None | 0.82A | 1w5uA-5yimA:undetectable1w5uB-5yimA:undetectable | 1w5uA-5yimA:undetectable1w5uB-5yimA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a2f | - (-) |
no annotation | 3 | TRP A 324ALA A 326VAL A 330 | None | 0.94A | 1w5uA-6a2fA:undetectable1w5uB-6a2fA:undetectable | 1w5uA-6a2fA:undetectable1w5uB-6a2fA:undetectable |