SIMILAR PATTERNS OF AMINO ACIDS FOR 1VQ1_A_SAMA301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b2p PROTEIN (LECTIN)

(Hyacinthoides
hispanica) 		PF01453
(B_lectin) 		3 GLY A  57
ASP A  39
ASN A  55
 None
 0.61A 1vq1A-1b2pA:
undetectable		 1vq1A-1b2pA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dus MJ0882

(Methanocaldococcus
jannaschii) 		PF05175
(MTS) 		3 GLY A  63
ASP A  84
ASN A 129
 None
 0.18A 1vq1A-1dusA:
18.9		 1vq1A-1dusA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		3 GLY A 153
ASP A  82
ASN A 155
 None
 0.64A 1vq1A-1e0tA:
4.0		 1vq1A-1e0tA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1h BOTULINUM NEUROTOXIN
TYPE A LIGHT CHAIN

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		3 GLY A  56
ASP A  57
ASN A  52
 None
 0.60A 1vq1A-1e1hA:
undetectable		 1vq1A-1e1hA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4e VANCOMYCIN/TEICOPLAN
IN A-TYPE RESISTANCE
PROTEIN VANA

(Enterococcus
faecium) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		3 GLY B 216
ASP B 232
ASN B 304
 None
None
ADP  B 350 (-3.3A)
 0.61A 1vq1A-1e4eB:
undetectable		 1vq1A-1e4eB:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5g COMPLEMENT CONTROL
PROTEIN C3

(Vaccinia virus) 		PF00084
(Sushi) 		3 GLY A  38
ASP A  91
ASN A  36
 None
 0.65A 1vq1A-1e5gA:
undetectable		 1vq1A-1e5gA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1elt ELASTASE

(Salmo salar) 		PF00089
(Trypsin) 		3 GLY A 190
ASP A 194
ASN A 188
 None
 0.47A 1vq1A-1eltA:
undetectable		 1vq1A-1eltA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1im8 YECO

(Haemophilus
influenzae) 		PF13649
(Methyltransf_25) 		3 GLY A  63
ASP A  88
ASN A 131
 SAI  A 302 (-3.8A)
SAI  A 302 (-2.8A)
SAI  A 302 (-4.1A)
 0.56A 1vq1A-1im8A:
11.8		 1vq1A-1im8A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jpc AGGLUTININ

(Galanthus
nivalis) 		PF01453
(B_lectin) 		3 GLY A  46
ASP A  28
ASN A  44
 MAN  A 115 ( 4.7A)
MAN  A 115 (-3.1A)
MAN  A 117 (-3.1A)
 0.52A 1vq1A-1jpcA:
undetectable		 1vq1A-1jpcA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jpc AGGLUTININ

(Galanthus
nivalis) 		PF01453
(B_lectin) 		3 GLY A  78
ASP A  59
ASN A  76
 MAN  A 113 ( 4.8A)
MAN  A 113 (-3.2A)
MAN  A 114 (-3.1A)
 0.53A 1vq1A-1jpcA:
undetectable		 1vq1A-1jpcA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1la2 MYO-INOSITOL-1-PHOSP
HATE SYNTHASE

(Saccharomyces
cerevisiae) 		PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5) 		3 GLY A  72
ASP A 148
ASN A  77
 NAD  A 900 (-3.3A)
NAD  A 900 (-3.0A)
NAD  A 900 (-2.9A)
 0.51A 1vq1A-1la2A:
undetectable		 1vq1A-1la2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lxy ARGININE DEIMINASE

(Mycoplasma
arginini) 		PF02274
(Amidinotransf) 		3 GLY A 228
ASP A 216
ASN A 260
 None
 0.62A 1vq1A-1lxyA:
undetectable		 1vq1A-1lxyA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne2 HYPOTHETICAL PROTEIN
TA1320

(Thermoplasma
acidophilum) 		PF06325
(PrmA) 		3 GLY A  56
ASP A  78
ASN A 114
 None
 0.33A 1vq1A-1ne2A:
14.1		 1vq1A-1ne2A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT

(Mycobacterium
tuberculosis) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		3 GLY A 575
ASP A 576
ASN A 396
 None
 0.64A 1vq1A-1nl3A:
undetectable		 1vq1A-1nl3A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Achromobacter
xylosoxidans) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 GLY O 227
ASP O 226
ASN O 230
 None
 0.52A 1vq1A-1obfO:
3.3		 1vq1A-1obfO:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qdm PROPHYTEPSIN

(Hordeum vulgare) 		PF00026
(Asp)
PF03489
(SapB_2)
PF05184
(SapB_1) 		3 GLY A 225
ASP A  36
ASN A  15
 None
 0.66A 1vq1A-1qdmA:
undetectable		 1vq1A-1qdmA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu9 YJGF PROTEIN

(Escherichia
coli) 		PF01042
(Ribonuc_L-PSP) 		3 GLY A  69
ASP A  70
ASN A  99
 None
 0.59A 1vq1A-1qu9A:
undetectable		 1vq1A-1qu9A:
17.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sg9 HEMK PROTEIN

(Thermotoga
maritima) 		PF05175
(MTS) 		3 GLY A 129
ASP A 151
ASN A 197
 SAM  A 301 (-3.3A)
SAM  A 301 (-2.9A)
GLN  A 400 ( 3.1A)
 0.10A 1vq1A-1sg9A:
39.6		 1vq1A-1sg9A:
95.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tid ANTI-SIGMA F FACTOR

(Geobacillus
stearothermophilus) 		PF13581
(HATPase_c_2) 		3 GLY A 129
ASP A  81
ASN A 127
 None
ATP  A 200 (-4.0A)
None
 0.58A 1vq1A-1tidA:
undetectable		 1vq1A-1tidA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tp8 AGGLUTININ ALPHA
CHAIN

(Artocarpus
hirsutus) 		PF01419
(Jacalin) 		3 GLY A  26
ASP A  27
ASN A  20
 None
 0.58A 1vq1A-1tp8A:
undetectable		 1vq1A-1tp8A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9n MALATE DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF02615
(Ldh_2) 		3 GLY A  92
ASP A  91
ASN A 126
 None
 0.65A 1vq1A-1v9nA:
undetectable		 1vq1A-1v9nA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vko INOSITOL-3-PHOSPHATE
SYNTHASE

(Caenorhabditis
elegans) 		PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5) 		3 GLY A  71
ASP A 148
ASN A  76
 NAD  A 601 (-3.2A)
NAD  A 601 (-2.7A)
NAD  A 601 ( 2.9A)
 0.51A 1vq1A-1vkoA:
undetectable		 1vq1A-1vkoA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vm7 RIBOKINASE

(Thermotoga
maritima) 		PF00294
(PfkB) 		3 GLY A 216
ASP A 217
ASN A 178
 None
 0.62A 1vq1A-1vm7A:
3.7		 1vq1A-1vm7A:
27.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wuf HYPOTHETICAL PROTEIN
LIN2664

(Listeria
innocua) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLY A1347
ASP A1110
ASN A1345
 None
 0.59A 1vq1A-1wufA:
undetectable		 1vq1A-1wufA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ynq OXIDOREDUCTASE

(Bacillus
halodurans) 		PF00248
(Aldo_ket_red) 		3 GLY A  54
ASP A  49
ASN A  56
 None
 0.54A 1vq1A-1ynqA:
undetectable		 1vq1A-1ynqA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5h L-LYSINE
2,3-AMINOMUTASE

(Clostridium
subterminale) 		PF04055
(Radical_SAM)
PF12544
(LAM_C) 		3 GLY A 264
ASP A 267
ASN A  73
 None
 0.58A 1vq1A-2a5hA:
undetectable		 1vq1A-2a5hA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aj4 GALACTOKINASE

(Saccharomyces
cerevisiae) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C)
PF10509
(GalKase_gal_bdg) 		3 GLY A 308
ASP A 312
ASN A 306
 None
 0.66A 1vq1A-2aj4A:
undetectable		 1vq1A-2aj4A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ark FLAVODOXIN

(Aquifex
aeolicus) 		PF00258
(Flavodoxin_1) 		3 GLY A 116
ASP A  84
ASN A 114
 None
 0.48A 1vq1A-2arkA:
2.6		 1vq1A-2arkA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3t PROTEIN
METHYLTRANSFERASE
HEMK

(Escherichia
coli) 		PF13847
(Methyltransf_31) 		3 GLY A 117
ASP A 140
ASN A 183
 SAH  A 300 (-3.4A)
SAH  A 300 (-3.1A)
SAH  A 300 (-3.9A)
 0.22A 1vq1A-2b3tA:
30.1		 1vq1A-2b3tA:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1d SOXA

(Paracoccus
denitrificans) 		no annotation 3 GLY A 215
ASP A  27
ASN A 213
 None
 0.58A 1vq1A-2c1dA:
undetectable		 1vq1A-2c1dA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfc 2-(R)-HYDROXYPROPYL-
COM DEHYDROGENASE

(Xanthobacter
autotrophicus) 		PF13561
(adh_short_C2) 		3 GLY A   9
ASP A  33
ASN A  14
 NAD  A1251 (-3.5A)
NAD  A1251 (-2.7A)
NAD  A1251 (-2.7A)
 0.58A 1vq1A-2cfcA:
6.6		 1vq1A-2cfcA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2a ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Staphylococcus
aureus) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		3 GLY B 117
ASP B 156
ASN B 102
 None
 0.63A 1vq1A-2f2aB:
undetectable		 1vq1A-2f2aB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT

(Thermus
thermophilus) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		3 GLY A 686
ASP A 687
ASN A 409
 None
 0.67A 1vq1A-2ipcA:
3.4		 1vq1A-2ipcA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf4 PERIPLASMIC
TREHALASE

(Escherichia
coli) 		PF01204
(Trehalase) 		3 GLY A 244
ASP A 243
ASN A 247
 None
 0.54A 1vq1A-2jf4A:
undetectable		 1vq1A-2jf4A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2krb EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT B

(Homo sapiens) 		PF00076
(RRM_1) 		3 GLY A  83
ASP A  82
ASN A  22
 None
 0.67A 1vq1A-2krbA:
undetectable		 1vq1A-2krbA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mki CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 4

(Homo sapiens) 		PF16367
(RRM_7) 		3 GLY A 198
ASP A 194
ASN A 224
 None
 0.55A 1vq1A-2mkiA:
undetectable		 1vq1A-2mkiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8e DNA MISMATCH REPAIR
PROTEIN MSH6

(Homo sapiens) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		3 GLY B 770
ASP B1058
ASN B 534
 None
 0.65A 1vq1A-2o8eB:
2.4		 1vq1A-2o8eB:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p35 TRANS-ACONITATE
2-METHYLTRANSFERASE

(Agrobacterium
fabrum) 		PF13489
(Methyltransf_23) 		3 GLY A  38
ASP A  61
ASN A  99
 SAH  A 301 (-3.6A)
SAH  A 301 (-2.7A)
SAH  A 301 (-3.8A)
 0.59A 1vq1A-2p35A:
11.4		 1vq1A-2p35A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pgg RNA-DIRECTED RNA
POLYMERASE

(Infectious
bursal disease
virus) 		PF04197
(Birna_RdRp) 		3 GLY A 481
ASP A 467
ASN A 423
 None
 0.66A 1vq1A-2pggA:
2.6		 1vq1A-2pggA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjd RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE C

(Escherichia
coli) 		PF05175
(MTS)
PF08468
(MTS_N) 		3 GLY A 204
ASP A 227
ASN A 268
 None
 0.54A 1vq1A-2pjdA:
18.2		 1vq1A-2pjdA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 3 GLY A 524
ASP A 525
ASN A 494
 None
 0.54A 1vq1A-2po4A:
undetectable		 1vq1A-2po4A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w5f ENDO-1,4-BETA-XYLANA
SE Y

(Ruminiclostridium
thermocellum) 		PF00331
(Glyco_hydro_10)
PF02018
(CBM_4_9) 		3 GLY A  64
ASP A 173
ASN A  62
 None
CD  A1559 (-2.1A)
None
 0.53A 1vq1A-2w5fA:
undetectable		 1vq1A-2w5fA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wed PENICILLOPEPSIN

(Penicillium
janthinellum) 		PF00026
(Asp) 		3 GLY A 207
ASP A 206
ASN A 194
 None
 0.66A 1vq1A-2wedA:
undetectable		 1vq1A-2wedA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wrt GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME 51

(Fasciola
hepatica) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		3 GLY A 138
ASP A 139
ASN A 135
 None
 0.60A 1vq1A-2wrtA:
undetectable		 1vq1A-2wrtA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt4 MCBG-LIKE PROTEIN

(Xanthomonas
albilineans) 		PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4) 		3 GLY A 149
ASP A 129
ASN A 167
 None
 0.60A 1vq1A-2xt4A:
undetectable		 1vq1A-2xt4A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yo3 GENERAL CONTROL
PROTEIN GCN4,
PUTATIVE INNER
MEMBRANE PROTEIN,
GENERAL CONTROL
PROTEIN GCN4

(Saccharomyces
cerevisiae;
Salmonella
enterica) 		PF05662
(YadA_stalk) 		3 GLY A1331
ASP A1332
ASN A1329
 None
 0.64A 1vq1A-2yo3A:
undetectable		 1vq1A-2yo3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0e MANNOSE/SIALIC
ACID-BINDING LECTIN

(Polygonatum
cyrtonema) 		PF01453
(B_lectin) 		3 GLY A  47
ASP A  29
ASN A  45
 SO4  A 112 ( 3.7A)
SO4  A 112 ( 2.7A)
None
 0.60A 1vq1A-3a0eA:
undetectable		 1vq1A-3a0eA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bs9 NUCLEOLYSIN TIA-1
ISOFORM P40

(Homo sapiens) 		PF00076
(RRM_1) 		3 GLY A 100
ASP A 101
ASN A 169
 None
 0.65A 1vq1A-3bs9A:
undetectable		 1vq1A-3bs9A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli) 		PF07517
(SecA_DEAD) 		3 GLY A 579
ASP A 580
ASN A 415
 None
 0.65A 1vq1A-3bxzA:
3.4		 1vq1A-3bxzA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE

(Trichormus
variabilis) 		PF08241
(Methyltransf_11) 		3 GLY A  46
ASP A  67
ASN A 105
 None
 0.38A 1vq1A-3ccfA:
12.0		 1vq1A-3ccfA:
27.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cjt RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE

(Thermus
thermophilus) 		PF06325
(PrmA) 		3 GLY A 128
ASP A 149
ASN A 191
 SAH  A 258 (-3.1A)
SAH  A 258 (-2.8A)
SAH  A 258 ( 3.8A)
 0.26A 1vq1A-3cjtA:
16.9		 1vq1A-3cjtA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cz8 PUTATIVE
SPORULATION-SPECIFIC
GLYCOSYLASE YDHD

(Bacillus
subtilis) 		PF00704
(Glyco_hydro_18) 		3 GLY A 139
ASP A 140
ASN A 184
 None
 0.66A 1vq1A-3cz8A:
undetectable		 1vq1A-3cz8A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkh LACCASE-1

(Melanocarpus
albomyces) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 GLY A 558
ASP A 556
ASN A 109
 None
 0.60A 1vq1A-3dkhA:
undetectable		 1vq1A-3dkhA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dpr PROTEIN VP2

(Rhinovirus A) 		PF00073
(Rhv) 		3 GLY B  19
ASP B  20
ASN B  61
 None
 0.65A 1vq1A-3dprB:
undetectable		 1vq1A-3dprB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dx5 UNCHARACTERIZED
PROTEIN ASBF

(Bacillus
anthracis) 		PF01261
(AP_endonuc_2) 		3 GLY A  36
ASP A  69
ASN A  41
 None
 0.61A 1vq1A-3dx5A:
undetectable		 1vq1A-3dx5A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzw AGGLUTININ

(Narcissus
pseudonarcissus) 		PF01453
(B_lectin) 		3 GLY A  46
ASP A  28
ASN A  44
 MAN  A 113 ( 4.7A)
MAN  A 113 (-3.1A)
None
 0.58A 1vq1A-3dzwA:
undetectable		 1vq1A-3dzwA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzw AGGLUTININ

(Narcissus
pseudonarcissus) 		PF01453
(B_lectin) 		3 GLY A  78
ASP A  59
ASN A  76
 MAN  A 115 ( 4.8A)
MAN  A 115 (-2.9A)
None
 0.55A 1vq1A-3dzwA:
undetectable		 1vq1A-3dzwA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8s PUTATIVE SAM
DEPENDENT
METHYLTRANSFERASE

(Pseudomonas
putida) 		PF13489
(Methyltransf_23) 		3 GLY A  59
ASP A  80
ASN A 122
 SAH  A 300 (-4.2A)
SAH  A 300 (-2.7A)
SAH  A 300 (-3.8A)
 0.54A 1vq1A-3e8sA:
11.3		 1vq1A-3e8sA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ee1 EFFECTOR PROTEIN
VIRA

(Shigella
flexneri) 		PF06872
(EspG) 		3 GLY A  76
ASP A  75
ASN A 130
 None
 0.66A 1vq1A-3ee1A:
undetectable		 1vq1A-3ee1A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fna POSSIBLE ARABINOSE
5-PHOSPHATE
ISOMERASE

(Escherichia
coli) 		PF00571
(CBS) 		3 GLY A 245
ASP A 262
ASN A 243
 None
 0.67A 1vq1A-3fnaA:
undetectable		 1vq1A-3fnaA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1w SUGAR ABC
TRANSPORTER

(Bacillus
halodurans) 		PF13407
(Peripla_BP_4) 		3 GLY A 239
ASP A 242
ASN A 235
 None
 0.60A 1vq1A-3g1wA:
4.6		 1vq1A-3g1wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gef LAMIN-A/C

(Homo sapiens) 		PF00932
(LTD) 		3 GLY A 474
ASP A 476
ASN A 524
 None
 0.64A 1vq1A-3gefA:
undetectable		 1vq1A-3gefA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3grz RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE

(Lactobacillus
delbrueckii) 		PF06325
(PrmA) 		3 GLY A 184
ASP A 206
ASN A 248
 GOL  A 322 ( 3.7A)
GOL  A 322 (-3.5A)
None
 0.24A 1vq1A-3grzA:
16.0		 1vq1A-3grzA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iay DNA POLYMERASE DELTA
CATALYTIC SUBUNIT

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 GLY A 930
ASP A 953
ASN A 932
 None
 0.65A 1vq1A-3iayA:
undetectable		 1vq1A-3iayA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibz PUTATIVE TELLURIUM
RESISTANT LIKE
PROTEIN TERD

(Streptomyces
coelicolor) 		PF02342
(TerD) 		3 GLY A  28
ASP A  88
ASN A 126
 CA  A 193 ( 4.9A)
CA  A 193 (-2.3A)
None
 0.62A 1vq1A-3ibzA:
undetectable		 1vq1A-3ibzA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jc7 DNA REPLICATION
COMPLEX GINS PROTEIN
SLD5

(Saccharomyces
cerevisiae) 		PF05916
(Sld5)
PF16922
(SLD5_C) 		3 GLY D 104
ASP D 107
ASN D 100
 None
 0.50A 1vq1A-3jc7D:
undetectable		 1vq1A-3jc7D:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mml ALLOPHANATE
HYDROLASE SUBUNIT 2
ALLOPHANATE
HYDROLASE SUBUNIT 1

(Mycolicibacterium
smegmatis;
Mycolicibacterium
smegmatis) 		PF02626
(CT_A_B)
PF02682
(CT_C_D) 		3 GLY A 183
ASP A 186
ASN B   8
 None
 0.62A 1vq1A-3mmlA:
undetectable		 1vq1A-3mmlA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3na6 SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE

(Ruegeria sp.
TM1040) 		PF04952
(AstE_AspA) 		3 GLY A  59
ASP A  60
ASN A  57
 None
 0.64A 1vq1A-3na6A:
undetectable		 1vq1A-3na6A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		3 GLY A 299
ASP A 300
ASN A 323
 None
 0.56A 1vq1A-3nnkA:
4.1		 1vq1A-3nnkA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o31 THERMONICOTIANAMINE
SYNTHASE

(Methanothermobacter
thermautotrophicus) 		PF03059
(NAS) 		3 GLY A 173
ASP A 172
ASN A 175
 None
 0.63A 1vq1A-3o31A:
12.0		 1vq1A-3o31A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		3 GLY A 750
ASP A 753
ASN A 746
 None
 0.59A 1vq1A-3opyA:
undetectable		 1vq1A-3opyA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8s JACALIN

(Artocarpus
heterophyllus) 		PF01419
(Jacalin) 		3 GLY A  50
ASP A  51
ASN A  44
 None
 0.59A 1vq1A-3p8sA:
undetectable		 1vq1A-3p8sA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pg5 UNCHARACTERIZED
PROTEIN

(Corynebacterium
diphtheriae) 		PF13614
(AAA_31) 		3 GLY A 162
ASP A  39
ASN A   8
 None
 0.65A 1vq1A-3pg5A:
undetectable		 1vq1A-3pg5A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q87 N6 ADENINE SPECIFIC
DNA METHYLASE

(Encephalitozoon
cuniculi) 		PF05175
(MTS) 		3 GLY B  31
ASP B  51
ASN B  85
 SAM  B 300 (-3.5A)
SAM  B 300 (-2.9A)
SAM  B 300 (-3.9A)
 0.31A 1vq1A-3q87B:
17.7		 1vq1A-3q87B:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3se7 VANA

(-) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		3 GLY A 213
ASP A 229
ASN A 301
 None
None
ATP  A 400 ( 2.9A)
 0.52A 1vq1A-3se7A:
undetectable		 1vq1A-3se7A:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suj CERATO-PLATANIN 1

(Moniliophthora
perniciosa) 		PF07249
(Cerato-platanin) 		3 GLY A  56
ASP A  57
ASN A  31
 None
 0.65A 1vq1A-3sujA:
undetectable		 1vq1A-3sujA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3te6 REGULATORY PROTEIN
SIR3

(Saccharomyces
cerevisiae) 		no annotation 3 GLY A 797
ASP A 581
ASN A 794
 None
 0.30A 1vq1A-3te6A:
undetectable		 1vq1A-3te6A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thz DNA MISMATCH REPAIR
PROTEIN MSH2

(Homo sapiens) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		3 GLY A 338
ASP A 603
ASN A 343
 None
 0.66A 1vq1A-3thzA:
2.9		 1vq1A-3thzA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u37 ACETYL-XYLAN
ESTERASE EST2A

(Butyrivibrio
proteoclasticus) 		PF13472
(Lipase_GDSL_2) 		3 GLY A 194
ASP A 196
ASN A 202
 None
 0.62A 1vq1A-3u37A:
undetectable		 1vq1A-3u37A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5n PUTATIVE
RHAMNOSIDASE

(Streptomyces
avermitilis) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		3 GLY A 696
ASP A 697
ASN A 690
 None
 0.65A 1vq1A-3w5nA:
undetectable		 1vq1A-3w5nA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wia NITRITE REDUCTASE

(Geobacillus
kaustophilus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 GLY A 276
ASP A 256
ASN A 234
 None
 0.50A 1vq1A-3wiaA:
undetectable		 1vq1A-3wiaA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wkq NITRITE REDUCTASE

(Geobacillus
thermodenitrificans) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 GLY A 276
ASP A 256
ASN A 234
 None
 0.50A 1vq1A-3wkqA:
undetectable		 1vq1A-3wkqA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wme ATP-BINDING
CASSETTE, SUB-FAMILY
B, MEMBER 1

(Cyanidioschyzon
merolae) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		3 GLY A 635
ASP A 634
ASN A 470
 None
 0.62A 1vq1A-3wmeA:
2.6		 1vq1A-3wmeA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4afr METACASPASE

(Trypanosoma
brucei) 		PF00656
(Peptidase_C14) 		3 GLY A  19
ASP A  16
ASN A  24
 None
 0.59A 1vq1A-4afrA:
undetectable		 1vq1A-4afrA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc7 ALKYLDIHYDROXYACETON
EPHOSPHATE SYNTHASE,
PEROXISOMAL

(Cavia porcellus) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		3 GLY A 327
ASP A 331
ASN A 324
 None
 0.52A 1vq1A-4bc7A:
undetectable		 1vq1A-4bc7A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d5g CYCLOHEXANE-1,2-DION
E HYDROLASE

(Azoarcus sp.
BH72) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 GLY A 290
ASP A 284
ASN A 562
 None
 0.66A 1vq1A-4d5gA:
2.5		 1vq1A-4d5gA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dcm RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G

(Escherichia
coli) 		PF05175
(MTS) 		3 GLY A 236
ASP A 259
ASN A 305
 SAM  A 401 (-3.5A)
SAM  A 401 (-2.9A)
SAM  A 401 (-3.8A)
 0.27A 1vq1A-4dcmA:
17.1		 1vq1A-4dcmA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4j ARGININE DEIMINASE

(Mycoplasma
penetrans) 		PF02274
(Amidinotransf) 		3 GLY A 272
ASP A 260
ASN A 304
 None
 0.63A 1vq1A-4e4jA:
undetectable		 1vq1A-4e4jA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3n UNCHARACTERIZED ACR,
COG1565 SUPERFAMILY

(Burkholderia
thailandensis) 		PF02636
(Methyltransf_28) 		3 GLY A 349
ASP A 352
ASN A 347
 None
 0.53A 1vq1A-4f3nA:
10.2		 1vq1A-4f3nA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g41 MTA/SAH NUCLEOSIDASE

(Streptococcus
pyogenes) 		PF01048
(PNP_UDP_1) 		3 GLY A 143
ASP A  93
ASN A 167
 GLY  A 143 ( 0.0A)
ASP  A  93 ( 0.6A)
ASN  A 167 ( 0.6A)
 0.62A 1vq1A-4g41A:
undetectable		 1vq1A-4g41A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gek TRNA
(CMO5U34)-METHYLTRAN
SFERASE

(Escherichia
coli) 		PF13649
(Methyltransf_25) 		3 GLY A  64
ASP A  89
ASN A 132
 GEK  A 302 (-3.7A)
GEK  A 302 (-2.8A)
GEK  A 302 (-3.7A)
 0.61A 1vq1A-4gekA:
12.2		 1vq1A-4gekA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4isc METHYLTRANSFERASE

(Pseudomonas
syringae group
genomosp. 3) 		PF05401
(NodS) 		3 GLY A  50
ASP A  71
ASN A  53
 BME  A 301 ( 4.7A)
None
None
 0.66A 1vq1A-4iscA:
10.7		 1vq1A-4iscA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iwn TRNA
(CMO5U34)-METHYLTRAN
SFERASE

(Escherichia
coli) 		PF13649
(Methyltransf_25) 		3 GLY A  64
ASP A  89
ASN A 132
 GEK  A 301 (-3.6A)
GEK  A 301 (-2.8A)
GEK  A 301 (-3.7A)
 0.59A 1vq1A-4iwnA:
12.4		 1vq1A-4iwnA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnd CA(2+)/CALMODULIN-DE
PENDENT PROTEIN
KINASE PHOSPHATASE

(Caenorhabditis
elegans) 		PF00481
(PP2C) 		3 GLY A 371
ASP A 374
ASN A 416
 None
 0.61A 1vq1A-4jndA:
2.3		 1vq1A-4jndA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4krg PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
1

(Haemonchus
contortus) 		PF08241
(Methyltransf_11) 		3 GLY A  59
ASP A  80
ASN A 122
 SAH  A 502 (-3.6A)
SAH  A 502 (-2.5A)
SAH  A 502 (-3.9A)
 0.46A 1vq1A-4krgA:
10.7		 1vq1A-4krgA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mju NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 GLY A 297
ASP A 293
ASN A 344
 CA  A 502 (-4.7A)
None
None
 0.59A 1vq1A-4mjuA:
undetectable		 1vq1A-4mjuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mu9 GLYCOSIDE HYDROLASE
FAMILY 73

(Bacteroides
thetaiotaomicron) 		PF03663
(Glyco_hydro_76) 		3 GLY A 358
ASP A 374
ASN A 365
 None
 0.54A 1vq1A-4mu9A:
undetectable		 1vq1A-4mu9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mzu WXCM-LIKE PROTEIN

(Shewanella
denitrificans) 		PF00132
(Hexapep)
PF05523
(FdtA) 		3 GLY A  14
ASP A  15
ASN A  12
 None
 0.67A 1vq1A-4mzuA:
undetectable		 1vq1A-4mzuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnp LIPOPROTEIN

(Staphylococcus
aureus) 		PF01297
(ZnuA) 		3 GLY A  51
ASP A  52
ASN A  48
 None
 0.59A 1vq1A-4nnpA:
undetectable		 1vq1A-4nnpA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nuz ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F2

(Streptococcus
pyogenes) 		no annotation 3 GLY A 408
ASP A 407
ASN A 374
 None
 0.57A 1vq1A-4nuzA:
2.3		 1vq1A-4nuzA:
19.54