SIMILAR PATTERNS OF AMINO ACIDS FOR 1VE3_B_SAMB301_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cb8 | PROTEIN(CHONDROITINASE AC) (Pedobacterheparinus) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 5 | GLY A 394ILE A 276SER A 279ILE A 390SER A 357 | None | 1.16A | 1ve3B-1cb8A:undetectable | 1ve3B-1cb8A:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1deu | PROCATHEPSIN X (Homo sapiens) |
PF00112(Peptidase_C1) | 5 | ALA A 185GLY A 186ALA A 16ILE A 151SER A 183 | None | 1.14A | 1ve3B-1deuA:undetectable | 1ve3B-1deuA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ef7 | CATHEPSIN X (Homo sapiens) |
PF00112(Peptidase_C1) | 5 | ALA A 185GLY A 186ALA A 16ILE A 151SER A 183 | None | 1.15A | 1ve3B-1ef7A:undetectable | 1ve3B-1ef7A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eth | TRIACYLGLYCEROLACYL-HYDROLASE (Sus scrofa) |
PF00151(Lipase)PF01477(PLAT) | 5 | TYR A 271GLY A 175ALA A 197ILE A 75HIS A 148 | None | 1.09A | 1ve3B-1ethA:undetectable | 1ve3B-1ethA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8w | NADH PEROXIDASE (Enterococcusfaecalis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 165GLY A 161ALA A 169ILE A 208PHE A 332 | None | 1.14A | 1ve3B-1f8wA:4.0 | 1ve3B-1f8wA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpl | LIPASE (Equus caballus) |
PF00151(Lipase)PF01477(PLAT) | 5 | TYR A 270GLY A 174ALA A 196ILE A 74HIS A 147 | None | 1.16A | 1ve3B-1hplA:undetectable | 1ve3B-1hplA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jc9 | TECHYLECTIN-5A (Tachypleustridentatus) |
PF00147(Fibrinogen_C) | 5 | GLY A 212SER A 193ILE A 240HIS A 187PHE A 184 | None | 1.15A | 1ve3B-1jc9A:undetectable | 1ve3B-1jc9A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jji | CARBOXYLESTERASE (Archaeoglobusfulgidus) |
PF07859(Abhydrolase_3) | 5 | TYR A 85GLY A 163ILE A 185ALA A 247SER A 170 | None | 1.10A | 1ve3B-1jjiA:2.5 | 1ve3B-1jjiA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jkm | BREFELDIN A ESTERASE (Bacillussubtilis) |
PF07859(Abhydrolase_3) | 5 | TYR A 233GLY A 126ILE A 131HIS A 338PHE A 259 | None | 1.15A | 1ve3B-1jkmA:2.6 | 1ve3B-1jkmA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcw | CERULOPLASMIN (Homo sapiens) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | GLY A 536ILE A 357ALA A 359ILE A 530SER A 522 | None | 1.09A | 1ve3B-1kcwA:undetectable | 1ve3B-1kcwA:12.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kph | CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPIDSYNTHASE 1 (Mycobacteriumtuberculosis) |
PF02353(CMAS) | 5 | TYR A 16GLY A 74ILE A 136HIS A 141PHE A 142 | SAH A1900 ( 4.2A)SAH A1900 (-3.2A)SAH A1900 (-4.2A)SAH A1900 (-4.4A)SAH A1900 ( 4.6A) | 1.06A | 1ve3B-1kphA:16.9 | 1ve3B-1kphA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lvl | DIHYDROLIPOAMIDEDEHYDROGENASE (Pseudomonasputida) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 324GLY A 320ILE A 326ALA A 328ILE A 22 | None | 1.02A | 1ve3B-1lvlA:4.1 | 1ve3B-1lvlA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qv0 | OBELIN (Obelialongissima) |
PF00036(EF-hand_1)PF13202(EF-hand_5) | 5 | TYR A 190ALA A 186GLY A 188ARG A 173HIS A 175 | CZH A 201 (-4.3A)NoneNoneNoneCZH A 201 (-3.5A) | 1.05A | 1ve3B-1qv0A:undetectable | 1ve3B-1qv0A:24.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ve3 | HYPOTHETICAL PROTEINPH0226 (Pyrococcushorikoshii) |
PF13649(Methyltransf_25) | 6 | ALA A 46ILE A 68SER A 69ALA A 94ARG A 95ILE A 108 | SAM A 302 (-3.4A)SAM A 302 (-3.7A)SAM A 302 (-4.7A)SAM A 302 (-3.3A)NoneNone | 1.27A | 1ve3B-1ve3A:35.3 | 1ve3B-1ve3A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ve3 | HYPOTHETICAL PROTEINPH0226 (Pyrococcushorikoshii) |
PF13649(Methyltransf_25) | 12 | TYR A 7TYR A 13ALA A 46GLY A 48ILE A 68SER A 69ALA A 94ARG A 95ILE A 110SER A 112HIS A 115PHE A 116 | SAM A 302 (-4.6A)SAM A 302 (-3.4A)SAM A 302 (-3.4A)SAM A 302 (-3.6A)SAM A 302 (-3.7A)SAM A 302 (-4.7A)SAM A 302 (-3.3A)NoneSAM A 302 (-3.8A)SAM A 302 (-3.3A)SAM A 302 (-3.8A)SAM A 302 (-4.4A) | 0.49A | 1ve3B-1ve3A:35.3 | 1ve3B-1ve3A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl5 | UNKNOWN CONSERVEDPROTEIN BH2331 (Bacillushalodurans) |
PF08241(Methyltransf_11) | 5 | ALA A 50GLY A 52ALA A 99HIS A 120PHE A 121 | None | 1.00A | 1ve3B-1vl5A:21.3 | 1ve3B-1vl5A:26.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w1w | STRUCTURALMAINTENANCE OFCHROMOSOME 1 (Saccharomycescerevisiae) |
PF02463(SMC_N) | 5 | ALA A1172ARG A1176ILE A1188SER A 30PHE A 28 | None | 1.12A | 1ve3B-1w1wA:undetectable | 1ve3B-1w1wA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w8j | MYOSIN VA (Gallus gallus) |
PF00063(Myosin_head) | 5 | TYR A 658ILE A 438SER A 162ILE A 433SER A 158 | None | 1.06A | 1ve3B-1w8jA:undetectable | 1ve3B-1w8jA:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y14 | DNA-DIRECTED RNAPOLYMERASE II 32 KDAPOLYPEPTIDE (Saccharomycescerevisiae) |
PF03874(RNA_pol_Rpb4) | 5 | ALA A 178GLY A 181SER A 53ALA A 49ILE A 195 | None | 1.10A | 1ve3B-1y14A:undetectable | 1ve3B-1y14A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ado | MEDIATOR OF DNADAMAGE CHECKPOINTPROTEIN 1 (Homo sapiens) |
PF16770(RTT107_BRCT_5) | 5 | TYR A2025GLY A2023ALA A2074ILE A2017PHE A2064 | None | 0.96A | 1ve3B-2adoA:undetectable | 1ve3B-2adoA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dis | UNNAMED PROTEINPRODUCT (Homo sapiens) |
PF00076(RRM_1) | 5 | TYR A 59ALA A 55ILE A 40ARG A 22ILE A 84 | None | 1.08A | 1ve3B-2disA:undetectable | 1ve3B-2disA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9z | CHEMOTAXIS PROTEINCHEC (Thermotogamaritima) |
PF04509(CheC) | 5 | GLY A 80SER A 183ALA A 53ILE A 59PHE A 149 | None | 0.95A | 1ve3B-2f9zA:undetectable | 1ve3B-2f9zA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fzw | ALCOHOLDEHYDROGENASE CLASSIII CHI CHAIN (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 280GLY A 260ALA A 276SER A 264PHE A 197 | None | 1.16A | 1ve3B-2fzwA:5.8 | 1ve3B-2fzwA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gj3 | NITROGEN FIXATIONREGULATORY PROTEIN (Azotobactervinelandii) |
PF00989(PAS) | 5 | TYR A 110GLY A 59ALA A 50ILE A 72HIS A 133 | NoneNoneNoneNoneFAD A 500 ( 4.8A) | 1.09A | 1ve3B-2gj3A:undetectable | 1ve3B-2gj3A:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h1n | OLIGOENDOPEPTIDASE F (Geobacillusstearothermophilus) |
PF01432(Peptidase_M3) | 5 | ALA A 324GLY A 322ILE A 63ILE A 145HIS A 61 | None | 1.01A | 1ve3B-2h1nA:undetectable | 1ve3B-2h1nA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6l | ALDEHYDEDEHYDROGENASE FAMILY7 MEMBER A1 (Homo sapiens) |
PF00171(Aldedh) | 5 | ALA A 394ALA A 397ARG A 308HIS A 392PHE A 409 | None | 1.07A | 1ve3B-2j6lA:4.5 | 1ve3B-2j6lA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pby | GLUTAMINASE (Geobacilluskaustophilus) |
PF04960(Glutaminase) | 5 | GLY A 242ILE A 115ALA A 119ILE A 66SER A 65 | None | 1.09A | 1ve3B-2pbyA:undetectable | 1ve3B-2pbyA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph3 | 3-OXOACYL-[ACYLCARRIER PROTEIN]REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 5 | ALA A 18GLY A 14SER A 10ALA A 46ARG A 47 | None | 1.02A | 1ve3B-2ph3A:2.1 | 1ve3B-2ph3A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pp3 | L-TALARATE/GALACTARATE DEHYDRATASE (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | GLY A 77ILE A 135ALA A 93ILE A 62SER A 79 | None | 1.07A | 1ve3B-2pp3A:undetectable | 1ve3B-2pp3A:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qae | DIHYDROLIPOYLDEHYDROGENASE (Trypanosomacruzi) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 334GLY A 330ILE A 336ALA A 338ILE A 19 | None | 1.13A | 1ve3B-2qaeA:4.4 | 1ve3B-2qaeA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yuj | UBIQUITIN FUSIONDEGRADATION 1-LIKE (Homo sapiens) |
PF03152(UFD1) | 5 | TYR A 60GLY A 78ILE A 179SER A 178ARG A 144 | None | 1.03A | 1ve3B-2yujA:undetectable | 1ve3B-2yujA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zzr | UNSATURATEDGLUCURONYL HYDROLASE (Streptococcusagalactiae) |
PF07470(Glyco_hydro_88) | 5 | TYR A 347ALA A 307ALA A 250SER A 289PHE A 279 | None | 1.07A | 1ve3B-2zzrA:undetectable | 1ve3B-2zzrA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axx | 458AA LONGHYPOTHETICALENDO-1,4-BETA-GLUCANASE (Pyrococcushorikoshii) |
PF00150(Cellulase) | 5 | TYR A 299GLY A 345ILE A 389SER A 378PHE A 69 | None | 1.13A | 1ve3B-3axxA:undetectable | 1ve3B-3axxA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bus | METHYLTRANSFERASE (Lechevalieriaaerocolonigenes) |
PF08241(Methyltransf_11) | 6 | GLY A 71ILE A 92SER A 93ALA A 120SER A 138HIS A 141 | SAH A 274 (-3.4A)SAH A 274 (-4.0A)NoneSAH A 274 (-3.5A)NoneSAH A 274 (-4.0A) | 0.81A | 1ve3B-3busA:19.1 | 1ve3B-3busA:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxo | N,N-DIMETHYLTRANSFERASE (Streptomycesvenezuelae) |
PF13649(Methyltransf_25) | 5 | ALA A 46GLY A 48SER A 69ARG A 91SER A 108 | SAM A 238 (-3.2A)SAM A 238 ( 3.7A)SAM A 238 (-4.6A)SAM A 238 (-4.1A)SAM A 238 (-3.2A) | 0.85A | 1ve3B-3bxoA:18.7 | 1ve3B-3bxoA:25.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cny | INOSITOL CATABOLISMPROTEIN IOLE (Lactobacillusplantarum) |
PF01261(AP_endonuc_2) | 5 | ALA A 106GLY A 72ALA A 149HIS A 94PHE A 91 | NoneNoneNoneEDO A 302 ( 3.7A)None | 1.03A | 1ve3B-3cnyA:undetectable | 1ve3B-3cnyA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ege | PUTATIVEMETHYLTRANSFERASEFROM ANTIBIOTICBIOSYNTHESIS PATHWAY (Trichormusvariabilis) |
PF08241(Methyltransf_11) | 5 | GLY A 43SER A 64ALA A 84ILE A 100HIS A 105 | EDO A 261 ( 3.9A)NoneNoneNoneEDO A 261 ( 4.6A) | 0.85A | 1ve3B-3egeA:16.1 | 1ve3B-3egeA:27.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hkz | DNA-DIRECTED RNAPOLYMERASE SUBUNIT B (Sulfolobussolfataricus) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | TYR B 314ILE B 190ALA B 168ILE B 521HIS B 300 | None | 1.16A | 1ve3B-3hkzB:undetectable | 1ve3B-3hkzB:12.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3im8 | MALONYL ACYL CARRIERPROTEIN TRANSACYLASE (Streptococcuspneumoniae) |
PF00698(Acyl_transf_1) | 5 | ALA A 9GLY A 88ALA A 13ILE A 272SER A 69 | None | 1.11A | 1ve3B-3im8A:undetectable | 1ve3B-3im8A:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kd9 | COENZYME A DISULFIDEREDUCTASE (Pyrococcushorikoshii) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 168GLY A 171ALA A 164HIS A 203PHE A 330 | None | 1.13A | 1ve3B-3kd9A:4.4 | 1ve3B-3kd9A:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kkl | PROBABLE CHAPERONEPROTEIN HSP33 (Saccharomycescerevisiae) |
no annotation | 5 | ALA A 231ILE A 229SER A 226ILE A 134PHE A 38 | None | 1.16A | 1ve3B-3kklA:3.6 | 1ve3B-3kklA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kpx | APOPHOTOPROTEINCLYTIN-3 (Clytia gregaria) |
PF13202(EF-hand_5) | 5 | TYR A 193ALA A 189GLY A 191ARG A 176HIS A 178 | NoneNoneNoneNoneCZH A 201 (-3.3A) | 1.07A | 1ve3B-3kpxA:undetectable | 1ve3B-3kpxA:22.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3l8d | METHYLTRANSFERASE (Bacillusthuringiensis) |
PF08241(Methyltransf_11) | 5 | GLY A 63ILE A 83SER A 84ILE A 123SER A 125 | None | 1.00A | 1ve3B-3l8dA:18.6 | 1ve3B-3l8dA:30.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lib | HYPOTHETICAL SENSORYTRANSDUCTIONHISTIDINE KINASE (Methanosarcinamazei) |
PF02743(dCache_1) | 5 | TYR A 155GLY A 196SER A 72ALA A 86PHE A 131 | None | 1.00A | 1ve3B-3libA:undetectable | 1ve3B-3libA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1l | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Mycobacteriumtuberculosis) |
PF13561(adh_short_C2) | 5 | ALA A 387ILE A 444ALA A 389ARG A 445ILE A 370 | None | 0.92A | 1ve3B-3m1lA:7.3 | 1ve3B-3m1lA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oks | 4-AMINOBUTYRATETRANSAMINASE (Mycolicibacteriumsmegmatis) |
PF00202(Aminotran_3) | 6 | TYR A 322ALA A 328GLY A 324ILE A 294SER A 301ALA A 331 | None | 1.34A | 1ve3B-3oksA:undetectable | 1ve3B-3oksA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oms | PHNB PROTEIN (Bacillus cereus) |
PF06983(3-dmu-9_3-mt) | 5 | ALA A 18GLY A 16ILE A 66SER A 68ALA A 54 | None | 0.99A | 1ve3B-3omsA:undetectable | 1ve3B-3omsA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3px2 | N-METHYLTRANSFERASE (Streptomycesfradiae) |
PF13649(Methyltransf_25) | 5 | ALA A 58GLY A 60SER A 81ARG A 103SER A 120 | SAH A 263 (-3.5A)SAH A 263 (-3.3A)SAH A 263 (-4.7A)SAH A 263 ( 4.7A)SAH A 263 (-3.3A) | 0.82A | 1ve3B-3px2A:19.7 | 1ve3B-3px2A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q8n | 4-AMINOBUTYRATETRANSAMINASE (Mycolicibacteriumsmegmatis) |
PF00202(Aminotran_3) | 6 | TYR A 323ALA A 329GLY A 325ILE A 295SER A 302ALA A 332 | None | 1.34A | 1ve3B-3q8nA:2.0 | 1ve3B-3q8nA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qhb | SYMERYTHRIN (Cyanophoraparadoxa) |
PF02915(Rubrerythrin) | 5 | ALA A 120GLY A 116ALA A 124ILE A 103PHE A 64 | None | 1.13A | 1ve3B-3qhbA:undetectable | 1ve3B-3qhbA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpc | CUTINASE (Fusarium solani) |
PF01083(Cutinase) | 5 | ALA A 126GLY A 122ALA A 116SER A 129PHE A 102 | NoneMIR A 120 ( 4.0A)NoneNoneNone | 1.14A | 1ve3B-3qpcA:2.1 | 1ve3B-3qpcA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5p | RIBOSE 5-PHOSPHATEISOMERASE (Giardiaintestinalis) |
PF02502(LacAB_rpiB) | 5 | ALA A 105GLY A 107ILE A 62ALA A 103ILE A 69 | None | 1.10A | 1ve3B-3s5pA:undetectable | 1ve3B-3s5pA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s8m | ENOYL-ACP REDUCTASE (Xanthomonasoryzae) |
PF07055(Eno-Rase_FAD_bd)PF12241(Enoyl_reductase)PF12242(Eno-Rase_NADH_b) | 5 | ALA A 62GLY A 64ILE A 28ALA A 98PHE A 94 | None | 1.14A | 1ve3B-3s8mA:6.2 | 1ve3B-3s8mA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sdo | NITRILOTRIACETATEMONOOXYGENASE (Burkholderiapseudomallei) |
PF00296(Bac_luciferase) | 5 | ALA A 225ILE A 222SER A 217ALA A 252ILE A 212 | None | 1.15A | 1ve3B-3sdoA:undetectable | 1ve3B-3sdoA:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3toj | SET1/ASH2 HISTONEMETHYLTRANSFERASECOMPLEX SUBUNIT ASH2 (Homo sapiens) |
PF00622(SPRY) | 5 | TYR A 364GLY A 345SER A 473ALA A 318ILE A 396 | None | 1.05A | 1ve3B-3tojA:undetectable | 1ve3B-3tojA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uf0 | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Beutenbergiacavernae) |
PF13561(adh_short_C2) | 5 | ALA A 185GLY A 187ILE A 141ALA A 183SER A 146 | NoneNoneNAP A 274 (-4.3A)NoneNone | 1.01A | 1ve3B-3uf0A:6.7 | 1ve3B-3uf0A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3urh | DIHYDROLIPOYLDEHYDROGENASE (Sinorhizobiummeliloti) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 334GLY A 330ILE A 336ALA A 338ILE A 19 | None | 1.13A | 1ve3B-3urhA:undetectable | 1ve3B-3urhA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zu4 | PUTATIVE REDUCTASEYPO4104/Y4119/YP_4011 (Yersinia pestis) |
PF07055(Eno-Rase_FAD_bd)PF12241(Enoyl_reductase)PF12242(Eno-Rase_NADH_b) | 5 | ALA A 62GLY A 64ILE A 28ALA A 98PHE A 94 | None | 1.14A | 1ve3B-3zu4A:6.1 | 1ve3B-3zu4A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4atq | 4-AMINOBUTYRATETRANSAMINASE (Paenarthrobacteraurescens) |
PF00202(Aminotran_3) | 6 | TYR A 325ALA A 331GLY A 327ILE A 297SER A 304ALA A 334 | None | 1.35A | 1ve3B-4atqA:undetectable | 1ve3B-4atqA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avy | PROBABLE SHORT-CHAINDEHYDROGENASE (Pseudomonasaeruginosa) |
PF13561(adh_short_C2) | 5 | ALA A 175GLY A 177ILE A 131ALA A 173SER A 136 | None | 1.07A | 1ve3B-4avyA:6.7 | 1ve3B-4avyA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 5 | GLY V 957ILE V 800ALA V 802ILE V 951SER V 943 | None | 1.07A | 1ve3B-4bxsV:undetectable | 1ve3B-4bxsV:10.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d72 | GLYCOSIDE HYDROLASE (Streptococcuspneumoniae) |
PF08306(Glyco_hydro_98M)PF08307(Glyco_hydro_98C) | 5 | ALA A 792ILE A 816ARG A 827SER A 638PHE A 769 | None | 1.11A | 1ve3B-4d72A:undetectable | 1ve3B-4d72A:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4euf | PUTATIVE REDUCTASECA_C0462 (Clostridiumacetobutylicum) |
PF07055(Eno-Rase_FAD_bd)PF12241(Enoyl_reductase)PF12242(Eno-Rase_NADH_b) | 5 | ALA A 61GLY A 63ILE A 28ALA A 98PHE A 94 | None | 1.08A | 1ve3B-4eufA:5.9 | 1ve3B-4eufA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g6c | BETA-HEXOSAMINIDASE1 (Burkholderiacenocepacia) |
PF00933(Glyco_hydro_3) | 5 | ALA A 273GLY A 277SER A 232ALA A 269SER A 252 | None | 0.96A | 1ve3B-4g6cA:undetectable | 1ve3B-4g6cA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hp8 | 2-DEOXY-D-GLUCONATE3-DEHYDROGENASE (Agrobacteriumfabrum) |
PF13561(adh_short_C2) | 5 | ALA A 181GLY A 183ILE A 137ALA A 179SER A 142 | NoneNoneNAP A 301 (-4.5A)NoneNone | 1.03A | 1ve3B-4hp8A:6.9 | 1ve3B-4hp8A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iuy | SHORT CHAINDEHYDROGENASE/REDUCTASE (Acinetobacterbaumannii) |
PF00106(adh_short) | 5 | ALA A 188GLY A 190ILE A 144ALA A 186SER A 149 | None | 0.88A | 1ve3B-4iuyA:6.7 | 1ve3B-4iuyA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kh9 | HYPOTHETICAL PROTEIN (Legionellapneumophila) |
PF16024(DUF4785) | 5 | GLY A 66ILE A 171SER A 172ILE A 271SER A 83 | None | 1.13A | 1ve3B-4kh9A:undetectable | 1ve3B-4kh9A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kqc | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Brachyspiramurdochii) |
PF13407(Peripla_BP_4) | 5 | GLY A 112ILE A 297ALA A 47ILE A 87PHE A 60 | None | 1.16A | 1ve3B-4kqcA:undetectable | 1ve3B-4kqcA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9j | RYANODINE RECEPTOR 1 (Oryctolaguscuniculus) |
no annotation | 5 | TYR C1122GLY C1103SER C1193ALA C1077ILE C1153 | None | 1.15A | 1ve3B-4p9jC:undetectable | 1ve3B-4p9jC:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdr | NEUROPILIN-2 (Homo sapiens) |
PF00754(F5_F8_type_C) | 5 | ALA A 519GLY A 505ALA A 517ILE A 583SER A 579 | None | 1.11A | 1ve3B-4qdrA:undetectable | 1ve3B-4qdrA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r8x | URICASE (Bacillusfastidiosus) |
PF01014(Uricase) | 5 | GLY A 268ILE A 166ALA A 232ARG A 229ILE A 244 | None | 1.09A | 1ve3B-4r8xA:undetectable | 1ve3B-4r8xA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rjk | ACETOLACTATESYNTHASE (Bacillussubtilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 196GLY A 194ALA A 200ILE A 329HIS A 335 | None | 1.14A | 1ve3B-4rjkA:2.2 | 1ve3B-4rjkA:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u1g | RETICULOCYTE BINDINGPROTEIN 5 (Plasmodiumfalciparum) |
no annotation | 5 | GLY A 336ILE A 193SER A 192ALA A 205ILE A 213 | None | 1.16A | 1ve3B-4u1gA:undetectable | 1ve3B-4u1gA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u4e | THIOLASE (Sphaerobacterthermophilus) |
PF02803(Thiolase_C) | 5 | ALA A 55GLY A 75ILE A 57SER A 58ILE A 85 | None | 1.12A | 1ve3B-4u4eA:undetectable | 1ve3B-4u4eA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjl | INACTIVE DIPEPTIDYLPEPTIDASE 10 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | GLY A 654ILE A 566ILE A 721SER A 672PHE A 777 | None | 1.09A | 1ve3B-4wjlA:undetectable | 1ve3B-4wjlA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8n | SET1/ASH2 HISTONEMETHYLTRANSFERASECOMPLEX SUBUNIT ASH2 (Homo sapiens) |
PF00622(SPRY) | 5 | TYR A 364GLY A 345SER A 473ALA A 318ILE A 396 | None | 1.06A | 1ve3B-4x8nA:undetectable | 1ve3B-4x8nA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4za2 | 2-DEOXY-D-GLUCONATE3-DEHYDROGENASE (Pectobacteriumcarotovorum) |
PF13561(adh_short_C2) | 5 | ALA A 187GLY A 189ILE A 143ALA A 185SER A 148 | None | 1.07A | 1ve3B-4za2A:6.2 | 1ve3B-4za2A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zch | TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B (Homo sapiens) |
PF00229(TNF) | 5 | ALA A 256GLY A 205SER A 105ILE A 203PHE A 353 | None | 1.14A | 1ve3B-4zchA:undetectable | 1ve3B-4zchA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 5 | ALA A 395GLY A 391ILE A 397ALA A 399SER A 184 | None | 1.13A | 1ve3B-5aexA:undetectable | 1ve3B-5aexA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cm2 | TRNAMETHYLTRANSFERASE (Yarrowialipolytica) |
PF08241(Methyltransf_11) | 5 | GLY Z 66SER Z 85ALA Z 106ILE Z 122PHE Z 128 | None | 0.86A | 1ve3B-5cm2Z:17.1 | 1ve3B-5cm2Z:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ew5 | COLICIN-E9 (Escherichiacoli) |
PF03515(Cloacin) | 5 | GLY A 219ILE A 233SER A 234ALA A 212SER A 279 | None | 1.09A | 1ve3B-5ew5A:undetectable | 1ve3B-5ew5A:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gm2 | O-METHYLRANSFERASE (Streptomycesblastmyceticus) |
PF08241(Methyltransf_11) | 6 | GLY A 87SER A 109ALA A 136ILE A 152SER A 154HIS A 157 | SAH A 301 (-3.1A)NoneSAH A 301 (-3.4A)SAH A 301 (-4.1A)SAH A 301 (-4.4A)SAH A 301 ( 4.3A) | 0.65A | 1ve3B-5gm2A:18.4 | 1ve3B-5gm2A:25.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jd4 | LAE6 (unculturedbacterium) |
PF07859(Abhydrolase_3) | 5 | ALA A 156GLY A 158ALA A 183ILE A 115PHE A 313 | None | 1.04A | 1ve3B-5jd4A:undetectable | 1ve3B-5jd4A:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jyd | SHORT CHAINDEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | GLY A 77ILE A 81ALA A 286ILE A 115HIS A 56 | NoneNAD A 901 (-3.8A)NoneNoneNone | 0.96A | 1ve3B-5jydA:6.3 | 1ve3B-5jydA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kj2 | HISTONEACETYLTRANSFERASEP300 (Homo sapiens) |
PF08214(HAT_KAT11) | 5 | TYR A1585ILE A1517SER A1516SER A1497PHE A1343 | None | 1.07A | 1ve3B-5kj2A:undetectable | 1ve3B-5kj2A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lkz | HISTONEACETYLTRANSFERASEP300,HISTONEACETYLTRANSFERASEP300 (Homo sapiens) |
PF00439(Bromodomain)PF06001(DUF902)PF08214(HAT_KAT11) | 5 | TYR A1585ILE A1517SER A1516SER A1497PHE A1343 | None | 1.14A | 1ve3B-5lkzA:2.6 | 1ve3B-5lkzA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mi0 | RETICULOCYTEBINDING-LIKE PROTEIN5,RETICULOCYTEBINDING PROTEIN 5 (Plasmodiumfalciparum) |
no annotation | 5 | GLY A 336ILE A 193SER A 192ALA A 205ILE A 213 | None | 1.13A | 1ve3B-5mi0A:undetectable | 1ve3B-5mi0A:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nop | ATTACHMENTGLYCOPROTEIN (Mojianghenipavirus) |
PF00423(HN) | 5 | GLY A 352ILE A 355ALA A 289ILE A 580SER A 567 | None | 1.04A | 1ve3B-5nopA:undetectable | 1ve3B-5nopA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5osn | CAPSID PROTEIN (Enterovirus E) |
PF00073(Rhv) | 5 | ALA B 165GLY B 163ILE B 167ILE B 207HIS B 170 | None | 1.00A | 1ve3B-5osnB:undetectable | 1ve3B-5osnB:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w5y | RNA POLYMERASEI-SPECIFICTRANSCRIPTIONINITIATION FACTORRRN6 (Saccharomycescerevisiae) |
PF10214(Rrn6) | 5 | ALA O 426SER O 429ILE O 423SER O 437PHE O 489 | None | 1.10A | 1ve3B-5w5yO:undetectable | 1ve3B-5w5yO:12.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7k | OXAG (Penicilliumoxalicum) |
no annotation | 6 | ALA A 54GLY A 56ILE A 83SER A 84ALA A 110PHE A 132 | SAH A 301 (-3.4A)SAH A 301 (-3.4A)SAH A 301 (-3.9A)NoneSAH A 301 (-3.4A)SAH A 301 (-4.6A) | 0.84A | 1ve3B-5w7kA:20.2 | 1ve3B-5w7kA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7k | OXAG (Penicilliumoxalicum) |
no annotation | 6 | TYR A 20ALA A 54ILE A 83SER A 84ALA A 110PHE A 132 | SAH A 301 (-4.6A)SAH A 301 (-3.4A)SAH A 301 (-3.9A)NoneSAH A 301 (-3.4A)SAH A 301 (-4.6A) | 1.11A | 1ve3B-5w7kA:20.2 | 1ve3B-5w7kA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7m | GLANDICOLINE BO-METHYLTRANSFERASEROQN (Penicilliumrubens) |
no annotation | 5 | ALA A 54GLY A 56ILE A 83SER A 84ALA A 110 | SAH A 301 (-3.3A)SAH A 301 (-3.3A)SAH A 301 (-3.5A)NoneSAH A 301 (-3.5A) | 0.47A | 1ve3B-5w7mA:20.0 | 1ve3B-5w7mA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7m | GLANDICOLINE BO-METHYLTRANSFERASEROQN (Penicilliumrubens) |
no annotation | 5 | ALA A 54GLY A 56ILE A 83SER A 84PHE A 132 | SAH A 301 (-3.3A)SAH A 301 (-3.3A)SAH A 301 (-3.5A)NoneSAH A 301 (-4.5A) | 0.88A | 1ve3B-5w7mA:20.0 | 1ve3B-5w7mA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 5 | ALA A 151ILE A 147ILE A 65SER A 67PHE A 69 | None | 1.13A | 1ve3B-5wugA:undetectable | 1ve3B-5wugA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxi | CYTOCHROME P450 2C9 (Homo sapiens) |
no annotation | 5 | ALA A 82GLY A 79ILE A 389SER A 390ALA A 86 | None | 1.12A | 1ve3B-5xxiA:undetectable | 1ve3B-5xxiA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yb7 | L-AMINO ACIDOXIDASE/MONOOXYGENASE (Pseudomonas sp.AIU 813) |
no annotation | 5 | ALA A 472GLY A 471ALA A 515ILE A 461SER A 363 | FAD A 601 (-3.4A)NoneORN A 602 ( 3.5A)NoneFAD A 601 (-3.6A) | 1.15A | 1ve3B-5yb7A:undetectable | 1ve3B-5yb7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cip | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Moorellathermoacetica) |
no annotation | 5 | TYR A1038ALA A 986GLY A1065ALA A 877SER A 984 | None | 1.15A | 1ve3B-6cipA:3.8 | 1ve3B-6cipA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ei3 | PROTON-DEPENDENTOLIGOPEPTIDETRANSPORTER FAMILYPROTEIN (Xanthomonascampestris) |
no annotation | 5 | ALA A 129GLY A 131ARG A 37ILE A 100PHE A 69 | None | 1.06A | 1ve3B-6ei3A:undetectable | 1ve3B-6ei3A:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fvs | CYS-LOOPLIGAND-GATED IONCHANNEL (endosymbiont ofTevniajerichonana) |
no annotation | 5 | ALA A 229GLY A 231ILE A 226ILE A 209PHE A 217 | NoneBNG A 401 ( 2.9A)NoneBNG A 401 ( 4.8A)None | 1.13A | 1ve3B-6fvsA:undetectable | 1ve3B-6fvsA:undetectable |