SIMILAR PATTERNS OF AMINO ACIDS FOR 1USQ_B_CLMB1143

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a87 COLICIN N

(Escherichia
coli) 		PF01024
(Colicin) 		4 PRO A 101
PRO A 106
GLY A 107
TYR A 109
 None
 0.82A 1usqB-1a87A:
undetectable		 1usqB-1a87A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ad9 IGG CTM01 FAB (HEAVY
CHAIN)

(Homo sapiens) 		no annotation 4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.82A 1usqB-1ad9H:
1.0		 1usqB-1ad9H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cic PROTEIN (IG HEAVY
CHAIN V REGIONS)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.83A 1usqB-1cicB:
0.0		 1usqB-1cicB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d4e FLAVOCYTOCHROME C
FUMARATE REDUCTASE

(Shewanella
oneidensis) 		PF00890
(FAD_binding_2)
PF14537
(Cytochrom_c3_2) 		4 PRO A 160
GLY A 134
ILE A 130
GLY A 132
 None
FAD  A 600 (-3.1A)
None
FAD  A 600 (-3.4A)
 0.80A 1usqB-1d4eA:
0.0		 1usqB-1d4eA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1de4 HEMOCHROMATOSIS
PROTEIN

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 PRO A 236
GLY A 238
GLY A 240
TYR A 242
 None
 0.67A 1usqB-1de4A:
0.2		 1usqB-1de4A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1emt IGG ANTIBODY (HEAVY
CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.82A 1usqB-1emtH:
0.0		 1usqB-1emtH:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1for IGG2A-KAPPA 17-IA
FAB (HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.69A 1usqB-1forH:
0.0		 1usqB-1forH:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fpt IGG2A-KAPPA C3 FAB
(HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.74A 1usqB-1fptH:
1.3		 1usqB-1fptH:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iaw TYPE II RESTRICTION
ENZYME NAEI

(Lechevalieria
aerocolonigenes) 		PF09126
(NaeI) 		4 PRO A 267
GLY A 270
ILE A 218
GLY A 214
 None
 0.82A 1usqB-1iawA:
undetectable		 1usqB-1iawA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jv5 IG CHAIN HEAVY CHAIN
PRECURSOR V REGION

(Homo sapiens) 		PF07686
(V-set) 		4 GLY B 354
PRO B 353
ILE B 351
GLY B 356
 None
 0.77A 1usqB-1jv5B:
undetectable		 1usqB-1jv5B:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ko0 DIAMINOPIMELATE
DECARBOXYLASE

(Escherichia
coli) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 GLY A 270
PRO A 269
ILE A 267
GLY A 226
 PLP  A 540 (-3.3A)
None
None
PLP  A 540 (-3.6A)
 0.82A 1usqB-1ko0A:
undetectable		 1usqB-1ko0A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lbu MURAMOYL-PENTAPEPTID
E CARBOXYPEPTIDASE

(Streptomyces
albus) 		PF01471
(PG_binding_1)
PF08291
(Peptidase_M15_3) 		5 PRO A 190
GLY A 188
PRO A 209
ILE A 213
GLY A 186
 None
 1.27A 1usqB-1lbuA:
undetectable		 1usqB-1lbuA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lqt FPRA

(Mycobacterium
tuberculosis) 		PF07992
(Pyr_redox_2) 		4 PRO A  45
GLY A  12
ILE A   8
GLY A  10
 ACT  A1871 ( 4.1A)
FAD  A2457 (-3.6A)
None
FAD  A2457 (-3.2A)
 0.84A 1usqB-1lqtA:
undetectable		 1usqB-1lqtA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mex FAB 29G12 HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.77A 1usqB-1mexH:
undetectable		 1usqB-1mexH:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mj8 IMMUNOGLOBULIN
MS6-126

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqB-1mj8H:
undetectable		 1usqB-1mj8H:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pls PLECKSTRIN HOMOLOGY
DOMAIN

(Homo sapiens) 		PF00169
(PH) 		4 PRO A  44
GLY A  46
ILE A  33
TYR A  36
 None
 0.83A 1usqB-1plsA:
undetectable		 1usqB-1plsA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q0y FAB 9B1, HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.78A 1usqB-1q0yH:
undetectable		 1usqB-1q0yH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rvf FAB 17-IA

(Mus musculus) 		PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.69A 1usqB-1rvfH:
undetectable		 1usqB-1rvfH:
18.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ut1 DR HEMAGGLUTININ
STRUCTURAL SUBUNIT

(Escherichia
coli) 		PF04619
(Adhesin_Dr) 		6 PRO A  40
GLY A  42
PRO A  43
ILE A 111
GLY A 113
TYR A 115
 EDO  A1143 ( 4.3A)
None
None
None
None
None
 0.50A 1usqB-1ut1A:
27.4		 1usqB-1ut1A:
99.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wt5 ANTI EGFR ANTIBODY
FV REGION

(Homo sapiens) 		PF07686
(V-set) 		4 GLY A  54
PRO A  53
ILE A  51
GLY A  56
 None
 0.84A 1usqB-1wt5A:
undetectable		 1usqB-1wt5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yed IGG1 FAB FRAGMENT
(D.2.4)

(Mus musculus) 		no annotation 4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.79A 1usqB-1yedH:
undetectable		 1usqB-1yedH:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yee IGG2A FAB FRAGMENT
(D2.5)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.81A 1usqB-1yeeH:
undetectable		 1usqB-1yeeH:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ae0 MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE A

(Escherichia
coli) 		PF03562
(MltA)
PF06725
(3D) 		5 PRO X 104
GLY X 314
PRO X 315
GLY X 318
TYR X 102
 None
 1.04A 1usqB-2ae0X:
undetectable		 1usqB-2ae0X:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cqv MYOSIN LIGHT CHAIN
KINASE, SMOOTH
MUSCLE AND
NON-MUSCLE ISOZYMES

(Homo sapiens) 		PF07679
(I-set) 		4 GLY A   7
PRO A   8
ILE A  37
GLY A  33
 None
 0.71A 1usqB-2cqvA:
undetectable		 1usqB-2cqvA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2czt PROSTAGLANDIN-H2
D-ISOMERASE

(Mus musculus) 		PF00061
(Lipocalin) 		4 PRO A  98
PRO A 102
GLY A 103
TYR A 105
 None
 0.58A 1usqB-2cztA:
undetectable		 1usqB-2cztA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e27 ANTI-CIGUATOXIN
ANTIBODY, HEAVY
CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 GLY H  53
PRO H 521
ILE H  51
GLY H  55
 None
 0.79A 1usqB-2e27H:
undetectable		 1usqB-2e27H:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eh7 HUMANIZED KR127 FAB,
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 1usqB-2eh7H:
undetectable		 1usqB-2eh7H:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 PRO A 522
ILE A 504
GLY A 506
TYR A 508
 None
 0.64A 1usqB-2eyqA:
undetectable		 1usqB-2eyqA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp4 6-PHOSPHOGLUCONATE
DEHYDRATASE

(Shewanella
oneidensis) 		PF00920
(ILVD_EDD) 		4 PRO A 177
GLY A 179
PRO A 180
ILE A 344
 None
 0.78A 1usqB-2gp4A:
undetectable		 1usqB-2gp4A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jis CYSTEINE SULFINIC
ACID DECARBOXYLASE

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 PRO A  87
GLY A  85
ILE A  33
GLY A  36
 None
 0.83A 1usqB-2jisA:
undetectable		 1usqB-2jisA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pb7 E3 UBIQUITIN-PROTEIN
LIGASE UHRF1

(Homo sapiens) 		PF02182
(SAD_SRA) 		4 GLY A 588
PRO A 589
ILE A 598
GLY A 594
 None
 0.47A 1usqB-2pb7A:
undetectable		 1usqB-2pb7A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00106
(adh_short)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PRO A1071
GLY A1069
GLY A1074
TYR A1072
 None
 0.75A 1usqB-2pffA:
undetectable		 1usqB-2pffA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 PRO A 241
GLY A 243
GLY A 227
TYR A 229
 None
 0.69A 1usqB-2pncA:
undetectable		 1usqB-2pncA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qmw PREPHENATE
DEHYDRATASE

(Staphylococcus
aureus) 		PF00800
(PDT) 		5 PRO A  30
GLY A   7
PRO A   8
ILE A 129
GLY A  10
 None
 1.44A 1usqB-2qmwA:
undetectable		 1usqB-2qmwA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4s ANTIBODY FOR BETA2
ADRENOCEPTOR, HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.69A 1usqB-2r4sH:
undetectable		 1usqB-2r4sH:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ri6 2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE

(Paraburkholderia
xenovorans) 		PF12697
(Abhydrolase_6) 		4 GLY A  43
PRO A  44
ILE A 194
GLY A  45
 MLI  A   2 (-3.5A)
None
None
None
 0.78A 1usqB-2ri6A:
undetectable		 1usqB-2ri6A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwe ANTI-VEGF-B
MONOCLONAL ANTIBODY

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY E  53
PRO E  52
ILE E  51
GLY E  55
 None
 0.75A 1usqB-2vweE:
undetectable		 1usqB-2vweE:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y05 PROSTAGLANDIN
REDUCTASE 1

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 PRO A 252
GLY A 254
PRO A 255
ILE A 227
 None
 0.69A 1usqB-2y05A:
undetectable		 1usqB-2y05A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y27 PHENYLACETATE-COENZY
ME A LIGASE

(Burkholderia
cenocepacia) 		PF00501
(AMP-binding)
PF14535
(AMP-binding_C_2) 		4 GLY A 244
PRO A 245
ILE A 236
GLY A 238
 GOL  A 505 (-3.9A)
GOL  A 505 (-3.7A)
GOL  A 505 ( 4.5A)
GOL  A 505 ( 3.4A)
 0.85A 1usqB-2y27A:
undetectable		 1usqB-2y27A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y4o PHENYLACETATE-COENZY
ME A LIGASE

(Burkholderia
cenocepacia) 		PF00501
(AMP-binding)
PF14535
(AMP-binding_C_2) 		4 GLY A 248
PRO A 249
ILE A 240
GLY A 242
 DLL  A1441 ( 4.4A)
DLL  A1441 ( 4.0A)
DLL  A1441 (-4.7A)
DLL  A1441 (-4.1A)
 0.80A 1usqB-2y4oA:
undetectable		 1usqB-2y4oA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA

(Homo sapiens) 		PF04321
(RmlD_sub_bind) 		5 PRO A 221
PRO A 310
ILE A 313
GLY A 314
TYR A 186
 None
 1.44A 1usqB-2ydyA:
undetectable		 1usqB-2ydyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxe PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Methanocaldococcus
jannaschii) 		PF01135
(PCMT) 		4 PRO A 206
GLY A 156
PRO A 157
GLY A 178
 None
 0.72A 1usqB-2yxeA:
undetectable		 1usqB-2yxeA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z4q ANTI EGFR ANTIBODY
FAB, HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.76A 1usqB-2z4qB:
undetectable		 1usqB-2z4qB:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9g PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrobaculum
aerophilum) 		PF07995
(GSDH) 		4 PRO A  53
GLY A  55
GLY A  57
TYR A  59
 None
 0.48A 1usqB-3a9gA:
undetectable		 1usqB-3a9gA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwh E3 UBIQUITIN-PROTEIN
LIGASE UHRF1

(Homo sapiens) 		PF02182
(SAD_SRA) 		4 GLY A 588
PRO A 589
ILE A 598
GLY A 594
 None
 0.65A 1usqB-3dwhA:
undetectable		 1usqB-3dwhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus musculus) 		PF07686
(V-set) 		4 GLY F1053
PRO F1052
ILE F1051
GLY F1055
 None
 0.81A 1usqB-3esuF:
undetectable		 1usqB-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuu PUTATIVE
METALLOPEPTIDASE

(Chelativorans
sp. BNC1) 		PF07171
(MlrC_C)
PF07364
(DUF1485) 		4 GLY A 307
PRO A 308
ILE A  21
GLY A  72
 None
 0.80A 1usqB-3iuuA:
undetectable		 1usqB-3iuuA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j8v H16.14J HEAVY CHAIN

(Mus musculus) 		no annotation 4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 1usqB-3j8vH:
undetectable		 1usqB-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j8w H263.A2 HEAVY CHAIN

(Mus musculus) 		no annotation 4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.78A 1usqB-3j8wH:
undetectable		 1usqB-3j8wH:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j8z H16.1A HEAVY CHAIN

(Mus musculus) 		no annotation 4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.76A 1usqB-3j8zH:
undetectable		 1usqB-3j8zH:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ntc FAB HEAVY CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.84A 1usqB-3ntcH:
undetectable		 1usqB-3ntcH:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwr A RUBISCO-LIKE
PROTEIN

(Paraburkholderia
fungorum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 PRO A 388
GLY A 390
PRO A 391
ILE A 384
GLY A 394
 None
 1.22A 1usqB-3nwrA:
undetectable		 1usqB-3nwrA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.79A 1usqB-3nz8A:
undetectable		 1usqB-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps9 TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC

(Escherichia
coli) 		PF01266
(DAO)
PF05430
(Methyltransf_30) 		4 PRO A 299
GLY A 273
ILE A 269
GLY A 271
 None
FAD  A 669 (-3.3A)
None
FAD  A 669 (-3.5A)
 0.70A 1usqB-3ps9A:
undetectable		 1usqB-3ps9A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvc TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC

(Yersinia pestis) 		PF01266
(DAO)
PF05430
(Methyltransf_30) 		4 PRO A 299
GLY A 273
ILE A 269
GLY A 271
 None
FAD  A 690 (-3.3A)
None
FAD  A 690 (-3.3A)
 0.78A 1usqB-3pvcA:
undetectable		 1usqB-3pvcA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qum FAB 5D3D11 HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.83A 1usqB-3qumH:
undetectable		 1usqB-3qumH:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rcn BETA-N-ACETYLHEXOSAM
INIDASE

(Paenarthrobacter
aurescens) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b) 		4 PRO A 399
GLY A 381
ILE A 386
GLY A 385
 None
 0.80A 1usqB-3rcnA:
undetectable		 1usqB-3rcnA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))

(Marinobacter
hydrocarbonoclasticus) 		PF00171
(Aldedh) 		4 GLY A 389
PRO A 390
ILE A 327
GLY A 284
 None
 0.73A 1usqB-3rh9A:
undetectable		 1usqB-3rh9A:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t3o METAL DEPENDENT
HYDROLASE

(Thermus
thermophilus) 		PF07521
(RMMBL)
PF12706
(Lactamase_B_2) 		4 GLY A 360
PRO A 331
GLY A 332
TYR A 362
 None
 0.82A 1usqB-3t3oA:
undetectable		 1usqB-3t3oA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tt1 MOUSE MONOCLONAL
1GG2A FAB FRAGMENT,
KAPPA LIGHT CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.80A 1usqB-3tt1H:
undetectable		 1usqB-3tt1H:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v76 FLAVOPROTEIN

(Sinorhizobium
meliloti) 		PF03486
(HI0933_like) 		4 PRO A  40
GLY A  14
ILE A  10
GLY A  12
 None
FDA  A 547 (-3.4A)
None
FDA  A 547 (-3.4A)
 0.78A 1usqB-3v76A:
undetectable		 1usqB-3v76A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbd SINGLE CHAIN FV
FRAGMENT OF MAB735

(Mus musculus) 		PF07686
(V-set) 		4 GLY A 181
PRO A 180
ILE A 178
GLY A 183
 None
 0.82A 1usqB-3wbdA:
undetectable		 1usqB-3wbdA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ze6 PERIPLASMIC [NIFESE]
HYDROGENASE, SMALL
SUBUNIT

(Desulfovibrio
vulgaris) 		PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C) 		5 PRO A 160
GLY A 158
PRO A 157
ILE A 156
GLY A 119
 SF4  A 286 (-3.7A)
None
None
None
SF4  A 286 (-3.6A)
 1.50A 1usqB-3ze6A:
undetectable		 1usqB-3ze6A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ala FAB 2H12 HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.79A 1usqB-4alaH:
undetectable		 1usqB-4alaH:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmh HEAVY CHAIN OF
SAR650984-FAB
FRAGMENT

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.80A 1usqB-4cmhB:
undetectable		 1usqB-4cmhB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7u ENDOGLUCANASE II

(Neurospora
crassa) 		PF03443
(Glyco_hydro_61) 		4 GLY A  85
PRO A  86
ILE A 219
GLY A 114
 None
 0.84A 1usqB-4d7uA:
undetectable		 1usqB-4d7uA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(unidentified) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLY A 313
PRO A 314
ILE A 368
GLY A 316
 None
 0.85A 1usqB-4e4uA:
undetectable		 1usqB-4e4uA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eis POLYSACCHARIDE
MONOOXYGENASE-3

(Neurospora
crassa) 		PF03443
(Glyco_hydro_61) 		4 GLY B  84
PRO B  85
ILE B 217
GLY B 117
 None
 0.85A 1usqB-4eisB:
undetectable		 1usqB-4eisB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj4 UNCHARACTERIZED
PROTEIN

(Halobacterium
salinarum) 		PF07920
(DUF1684) 		4 PRO A 138
GLY A 140
GLY A 144
TYR A  64
 None
 0.83A 1usqB-4fj4A:
undetectable		 1usqB-4fj4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gmk RIBOSE-5-PHOSPHATE
ISOMERASE A

(Lactobacillus
salivarius) 		PF06026
(Rib_5-P_isom_A) 		4 GLY A 220
PRO A 221
ILE A 214
GLY A 216
 None
 0.71A 1usqB-4gmkA:
undetectable		 1usqB-4gmkA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j8r HEAVY CHAIN OF POM2
FAB

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  53
PRO B  52
ILE B  51
GLY B  55
 None
 0.81A 1usqB-4j8rB:
undetectable		 1usqB-4j8rB:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kaq RITUXIMAB HEAVY
CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.74A 1usqB-4kaqH:
undetectable		 1usqB-4kaqH:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ki5 MURINE MONOCLONAL
G99 FAB HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY E  54
PRO E  53
ILE E  51
GLY E  56
 GLY  E  54 ( 0.0A)
PRO  E  53 ( 1.1A)
ILE  E  51 ( 0.7A)
GLY  E  56 ( 0.0A)
 0.77A 1usqB-4ki5E:
undetectable		 1usqB-4ki5E:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kuc MAB6C2 FAB-LIGHT
CHAIN

(Mus musculus) 		no annotation 4 GLY H  73
PRO H  72
ILE H  70
GLY H  75
 None
 0.74A 1usqB-4kucH:
undetectable		 1usqB-4kucH:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lcc BETA-2-MICROGLOBULIN
, MHC CLASS
I-RELATED PROTEIN

(Bos taurus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 PRO C 345
GLY C 347
GLY C 349
TYR C 351
 None
 0.73A 1usqB-4lccC:
undetectable		 1usqB-4lccC:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mt1 DRUG EFFLUX PROTEIN

(Neisseria
gonorrhoeae) 		PF00873
(ACR_tran) 		4 GLY A  51
PRO A  50
ILE A  48
GLY A  86
 None
 0.77A 1usqB-4mt1A:
undetectable		 1usqB-4mt1A:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mx8 PERIPLASMIC BINDING
PROTEIN

(Xylanimonas
cellulosilytica) 		PF01497
(Peripla_BP_2) 		5 PRO A 218
GLY A 181
ILE A 184
GLY A 183
TYR A 211
 None
 1.31A 1usqB-4mx8A:
undetectable		 1usqB-4mx8A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0y IGH526 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.85A 1usqB-4n0yH:
undetectable		 1usqB-4n0yH:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5f PUTATIVE ACYL-COA
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 GLY A  96
PRO A  97
ILE A 234
GLY A 100
 None
 0.79A 1usqB-4n5fA:
undetectable		 1usqB-4n5fA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN

(Homo sapiens) 		PF00129
(MHC_I)
PF07654
(C1-set) 		4 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.83A 1usqB-4nqeA:
undetectable		 1usqB-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsx U3 SMALL NUCLEOLAR
RNA-ASSOCIATED
PROTEIN 21

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 GLY A 538
ILE A 525
GLY A 527
TYR A 529
 None
 0.62A 1usqB-4nsxA:
undetectable		 1usqB-4nsxA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ol9 PUTATIVE
2-DEHYDROPANTOATE
2-REDUCTASE

(Mycobacterium
tuberculosis) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 GLY A   9
PRO A  10
ILE A  39
GLY A  14
 NAP  A 301 (-3.3A)
ACT  A 303 ( 3.4A)
None
None
 0.72A 1usqB-4ol9A:
undetectable		 1usqB-4ol9A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uok FAB FRAGMENT HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY A 272
PRO A 271
ILE A 269
GLY A 274
 None
 0.84A 1usqB-4uokA:
undetectable		 1usqB-4uokA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yji ARYL ACYLAMIDASE

(bacterium
CSBL00001) 		PF01425
(Amidase) 		4 GLY A 225
ILE A 227
GLY A 180
TYR A 116
 None
 0.83A 1usqB-4yjiA:
undetectable		 1usqB-4yjiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfq L,D-TRANSPEPTIDASE 5

(Mycobacterium
tuberculosis) 		PF03734
(YkuD) 		4 PRO A 242
GLY A 244
GLY A 246
TYR A 248
 None
 0.68A 1usqB-4zfqA:
undetectable		 1usqB-4zfqA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zso ANTIBODY HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.84A 1usqB-4zsoB:
undetectable		 1usqB-4zsoB:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cma ANTIBODY CH8H9 FAB
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.74A 1usqB-5cmaB:
undetectable		 1usqB-5cmaB:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1p ATP-DEPENDENT RNA
LIGASE

(Methanothermobacter
thermautotrophicus) 		PF09414
(RNA_ligase) 		4 PRO A 165
GLY A 168
PRO A 169
GLY A 154
 None
 0.84A 1usqB-5d1pA:
undetectable		 1usqB-5d1pA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eb5 HNL ISOENZYME 5

(Prunus dulcis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 PRO A 288
GLY A 273
ILE A 283
GLY A 271
 None
 0.82A 1usqB-5eb5A:
undetectable		 1usqB-5eb5A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f3j ANTIBODY 2D10 SINGLE
CHAIN VARIABLE
FRAGMENT

(Mus musculus) 		PF07686
(V-set) 		4 GLY C 223
PRO C 222
ILE C 220
GLY C 225
 None
 0.81A 1usqB-5f3jC:
undetectable		 1usqB-5f3jC:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g56 CARBOHYDRATE BINDING
FAMILY 6

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase)
PF03422
(CBM_6) 		4 PRO A 515
GLY A 566
GLY A 441
TYR A 443
 None
 0.78A 1usqB-5g56A:
1.7		 1usqB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g56 CARBOHYDRATE BINDING
FAMILY 6

(Ruminiclostridium
thermocellum) 		PF00150
(Cellulase)
PF03422
(CBM_6) 		4 PRO A 604
GLY A 606
GLY A 608
TYR A 610
 None
 0.80A 1usqB-5g56A:
1.7		 1usqB-5g56A:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz1 FRUCTOSE-1,6-BISPHOS
PHATASE

(Physcomitrella
patens) 		PF00316
(FBPase) 		5 PRO A 248
PRO A 376
ILE A 214
GLY A 216
TYR A 218
 None
 1.47A 1usqB-5iz1A:
undetectable		 1usqB-5iz1A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jm6 AMINOPEPTIDASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF02127
(Peptidase_M18) 		5 PRO A  51
GLY A 497
PRO A 496
ILE A 479
GLY A 499
 None
 1.33A 1usqB-5jm6A:
undetectable		 1usqB-5jm6A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jsy PERIPLASMIC [NIFESE]
HYDROGENASE, SMALL
SUBUNIT

(Desulfovibrio
vulgaris) 		PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C) 		5 PRO A 160
GLY A 158
PRO A 157
ILE A 156
GLY A 119
 SF4  A 303 ( 4.0A)
None
None
None
SF4  A 303 (-3.6A)
 1.47A 1usqB-5jsyA:
undetectable		 1usqB-5jsyA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kvd ZV-2 ANTIBODY FAB
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 1usqB-5kvdH:
undetectable		 1usqB-5kvdH:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5myx FAB C#24 HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  54
PRO B  53
ILE B  51
GLY B  56
 None
 0.80A 1usqB-5myxB:
undetectable		 1usqB-5myxB:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nlt CVAA9A

(Collariella
virescens) 		no annotation 4 GLY A  81
PRO A  82
ILE A 216
GLY A 109
 None
 0.84A 1usqB-5nltA:
undetectable		 1usqB-5nltA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ufv GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN

(Thermothelomyces
thermophila) 		PF03443
(Glyco_hydro_61) 		4 GLY A  78
PRO A  79
ILE A 219
GLY A 108
 None
 0.74A 1usqB-5ufvA:
undetectable		 1usqB-5ufvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w5x 3C10 FAB' HEAVY
CHAIN

(Rattus
norvegicus) 		no annotation 4 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.79A 1usqB-5w5xH:
undetectable		 1usqB-5w5xH:
undetectable