SIMILAR PATTERNS OF AMINO ACIDS FOR 1UPF_C_URFC999

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1brw PROTEIN (PYRIMIDINE
NUCLEOSIDE
PHOSPHORYLASE)

(Geobacillus
stearothermophilus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 ALA A 214
TYR A 429
ILE A 236
ASP A 238
 None
 1.04A 1upfC-1brwA:
undetectable		 1upfC-1brwA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2f MALY PROTEIN

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 MET A 306
ALA A 303
TYR A 301
ILE A 302
 None
 1.15A 1upfC-1d2fA:
4.1		 1upfC-1d2fA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fa7 GLYOXALASE I

(Escherichia
coli) 		PF00903
(Glyoxalase) 		4 ALA A  42
TYR A  20
ILE A  17
ASP A 115
 None
 1.14A 1upfC-1fa7A:
undetectable		 1upfC-1fa7A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g29 MALTOSE TRANSPORT
PROTEIN MALK

(Thermococcus
litoralis) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 ALA 1 124
TYR 1  99
ILE 1 102
ASP 1 117
 None
 0.89A 1upfC-1g291:
undetectable		 1upfC-1g291:
23.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1i5e URACIL
PHOSPHORIBOSYLTRANSF
ERASE

([Bacillus]
caldolyticus) 		PF14681
(UPRTase) 		5 MET A 133
ALA A 135
TYR A 193
ILE A 194
ASP A 200
 U5P  A 250 (-4.7A)
U5P  A 250 (-3.2A)
U5P  A 250 (-4.5A)
U5P  A 250 (-4.4A)
U5P  A 250 (-4.4A)
 0.58A 1upfC-1i5eA:
27.8		 1upfC-1i5eA:
36.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfu M-CALPAIN LARGE
SUBUNIT

(Homo sapiens) 		PF00648
(Peptidase_C2)
PF01067
(Calpain_III)
PF13833
(EF-hand_8) 		4 ALA L 630
TYR L 611
ILE L 610
ASP L 615
 None
 1.14A 1upfC-1kfuL:
undetectable		 1upfC-1kfuL:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kke SIGMA 1 PROTEIN

(Mammalian
orthoreovirus) 		PF01664
(Reo_sigma1) 		4 MET A 309
ALA A 301
TYR A 298
ILE A 300
 None
 1.16A 1upfC-1kkeA:
undetectable		 1upfC-1kkeA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nj8 PROLINE-TRNA
SYNTHETASE

(Methanocaldococcus
jannaschii) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09181
(ProRS-C_2) 		4 ALA A  56
TYR A 125
ILE A 124
ASP A  49
 None
 1.12A 1upfC-1nj8A:
undetectable		 1upfC-1nj8A:
19.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1o5o URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Thermotoga
maritima) 		PF14681
(UPRTase) 		5 MET A 133
ALA A 135
TYR A 193
ILE A 194
ASP A 200
 U5P  A 600 (-4.5A)
U5P  A 600 (-3.4A)
U5P  A 600 (-4.4A)
U5P  A 600 (-4.0A)
U5P  A 600 (-4.0A)
 0.50A 1upfC-1o5oA:
27.5		 1upfC-1o5oA:
36.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofe FERREDOXIN-DEPENDENT
GLUTAMATE SYNTHASE 2

(Synechocystis
sp. PCC 6803) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		4 ALA A 989
TYR A 987
ILE A 988
ASP A 907
 None
 1.15A 1upfC-1ofeA:
2.7		 1upfC-1ofeA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvj PYROGENIC EXOTOXIN B

(Streptococcus
pyogenes) 		PF01640
(Peptidase_C10)
PF13734
(Inhibitor_I69) 		4 ALA A 260
TYR A 240
ILE A 245
ASP A 267
 None
 1.15A 1upfC-1pvjA:
undetectable		 1upfC-1pvjA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ry2 ACETYL-COENZYME A
SYNTHETASE 1

(Saccharomyces
cerevisiae) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 ALA A 503
TYR A 469
ILE A 569
ASP A 559
 None
AMP  A 720 (-4.8A)
None
AMP  A 720 (-2.2A)
 1.13A 1upfC-1ry2A:
3.2		 1upfC-1ry2A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uwi BETA-GALACTOSIDASE

(Sulfolobus
solfataricus) 		PF00232
(Glyco_hydro_1) 		4 ALA A 292
TYR A 237
ILE A 240
ASP A 104
 None
 1.14A 1upfC-1uwiA:
2.5		 1upfC-1uwiA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v43 SUGAR-BINDING
TRANSPORT
ATP-BINDING PROTEIN

(Pyrococcus
horikoshii) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 ALA A 127
TYR A 102
ILE A 105
ASP A 120
 None
 0.97A 1upfC-1v43A:
undetectable		 1upfC-1v43A:
23.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1v9s URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Thermus
thermophilus) 		PF14681
(UPRTase) 		5 MET A 132
ALA A 134
TYR A 192
ILE A 193
ASP A 199
 None
SO4  A 517 (-3.3A)
None
None
SO4  A 514 ( 4.4A)
 0.47A 1upfC-1v9sA:
27.0		 1upfC-1v9sA:
37.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vb3 THREONINE SYNTHASE

(Escherichia
coli) 		PF00291
(PALP)
PF14821
(Thr_synth_N) 		4 ALA A 259
TYR A 225
ILE A 223
ASP A 252
 None
None
None
SO4  A 501 (-4.9A)
 1.16A 1upfC-1vb3A:
undetectable		 1upfC-1vb3A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcd MAJOR STRUCTURAL
PROTEIN VP2

(Infectious
bursal disease
virus) 		PF01766
(Birna_VP2) 		4 ALA J 232
TYR J 206
ILE J 308
ASP J 235
 None
 1.06A 1upfC-1wcdJ:
undetectable		 1upfC-1wcdJ:
19.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1xtt PROBABLE URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF14681
(UPRTase) 		5 MET A 142
ALA A 144
TYR A 202
ILE A 203
ASP A 209
 U5P  A1250 (-4.5A)
U5P  A1250 (-3.4A)
U5P  A1250 (-4.4A)
U5P  A1250 (-4.1A)
U5P  A1250 (-4.1A)
 0.51A 1upfC-1xttA:
24.0		 1upfC-1xttA:
34.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0f RAB14, MEMBER RAS
ONCOGENE FAMILY

(Homo sapiens) 		PF00071
(Ras) 		4 MET A  89
ALA A  87
ILE A 119
ASP A 108
 None
 1.09A 1upfC-1z0fA:
3.7		 1upfC-1z0fA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csg PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF07350
(DUF1479) 		4 ALA A 365
TYR A 184
ILE A 182
ASP A 390
 None
 1.17A 1upfC-2csgA:
undetectable		 1upfC-2csgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d62 MULTIPLE
SUGAR-BINDING
TRANSPORT
ATP-BINDING PROTEIN

(Pyrococcus
horikoshii) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 ALA A 127
TYR A 102
ILE A 105
ASP A 120
 None
 0.95A 1upfC-2d62A:
undetectable		 1upfC-2d62A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dk8 DNA-DIRECTED RNA
POLYMERASE III 39
KDA POLYPEPTIDE

(Mus musculus) 		PF05158
(RNA_pol_Rpc34) 		4 ALA A  50
TYR A  71
ILE A  19
ASP A  32
 None
 1.17A 1upfC-2dk8A:
undetectable		 1upfC-2dk8A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e2d METALLOPROTEINASE
INHIBITOR 2

(Bos taurus) 		PF00965
(TIMP) 		4 MET C1096
ALA C1090
ILE C1017
ASP C1102
 None
 1.06A 1upfC-2e2dC:
undetectable		 1upfC-2e2dC:
19.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2e55 URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Aquifex
aeolicus) 		PF14681
(UPRTase) 		4 MET A 130
ALA A 132
TYR A 190
ILE A 191
 None
SO4  A1301 (-3.1A)
None
None
 1.04A 1upfC-2e55A:
25.7		 1upfC-2e55A:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ehj URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Escherichia
coli) 		PF14681
(UPRTase) 		5 MET A 132
ALA A 134
TYR A 192
ILE A 193
ASP A 199
 None
SO4  A 210 (-3.5A)
None
None
None
 0.89A 1upfC-2ehjA:
26.9		 1upfC-2ehjA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0o SER/THR PHOSPHATASE

(Anopheles
gambiae) 		PF00481
(PP2C) 		4 MET A 570
ALA A 572
ILE A 520
ASP A 553
 None
 0.79A 1upfC-2i0oA:
undetectable		 1upfC-2i0oA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwb METHICILLIN
RESISTANCE MECR1
PROTEIN

(Staphylococcus
aureus) 		PF00905
(Transpeptidase) 		4 MET A 501
TYR A 459
ILE A 463
ASP A 403
 None
 1.17A 1upfC-2iwbA:
undetectable		 1upfC-2iwbA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kfk BUD EMERGENCE
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00564
(PB1) 		4 ALA A  35
TYR A  12
ILE A  34
ASP A  77
 None
 1.10A 1upfC-2kfkA:
undetectable		 1upfC-2kfkA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n8y ALPHA-ACTININ-1

(Homo sapiens) 		PF00036
(EF-hand_1)
PF08726
(EFhand_Ca_insen) 		4 MET A 864
ALA A 862
TYR A 859
ILE A 861
 None
 1.11A 1upfC-2n8yA:
undetectable		 1upfC-2n8yA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Archaeoglobus
fulgidus) 		PF00005
(ABC_tran) 		4 ALA A 111
TYR A  88
ILE A  91
ASP A 104
 None
 1.04A 1upfC-2onkA:
undetectable		 1upfC-2onkA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oox HYPOTHETICAL PROTEIN
C1556.08C IN
CHROMOSOME I

(Schizosaccharomyces
pombe) 		no annotation 4 MET G 200
ALA G 198
TYR G 232
ILE G 221
 None
 0.92A 1upfC-2ooxG:
undetectable		 1upfC-2ooxG:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pc1 ACETYLTRANSFERASE,
GNAT FAMILY

(Streptococcus
agalactiae) 		no annotation 4 ALA A  79
TYR A  77
ILE A  80
ASP A 129
 None
None
None
SO4  A 183 ( 4.8A)
 1.00A 1upfC-2pc1A:
undetectable		 1upfC-2pc1A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w92 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D

(Streptococcus
pneumoniae) 		PF03644
(Glyco_hydro_85) 		4 ALA A 515
TYR A 254
ILE A 514
ASP A 491
 None
 1.16A 1upfC-2w92A:
undetectable		 1upfC-2w92A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yjp PUTATIVE ABC
TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN, AMINO ACID

(Neisseria
gonorrhoeae) 		PF00497
(SBP_bac_3) 		4 MET A 254
ALA A 252
ILE A 251
ASP A  84
 None
 0.91A 1upfC-2yjpA:
undetectable		 1upfC-2yjpA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyz SUGAR ABC
TRANSPORTER,
ATP-BINDING PROTEIN

(Thermotoga
maritima) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 MET A 198
ALA A 201
ILE A 204
ASP A 219
 None
 0.83A 1upfC-2yyzA:
undetectable		 1upfC-2yyzA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z23 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Yersinia pestis) 		PF00496
(SBP_bac_5) 		4 ALA A  10
TYR A 494
ILE A 515
ASP A 242
 None
 0.84A 1upfC-2z23A:
undetectable		 1upfC-2z23A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajx 3-HEXULOSE-6-PHOSPHA
TE SYNTHASE

(Mycobacterium
gastri) 		PF00215
(OMPdecase) 		4 ALA A1188
TYR A1190
ILE A1189
ASP A1008
 None
 1.17A 1upfC-3ajxA:
undetectable		 1upfC-3ajxA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bvp TP901-1 INTEGRASE

(Lactococcus
phage TP901-1) 		PF00239
(Resolvase) 		4 ALA A   6
TYR A   8
ILE A   7
ASP A  47
 None
 1.10A 1upfC-3bvpA:
undetectable		 1upfC-3bvpA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3caw O-SUCCINYLBENZOATE
SYNTHASE

(Bdellovibrio
bacteriovorus) 		no annotation 4 MET A 150
ALA A 146
ILE A 145
ASP A 117
 None
 0.97A 1upfC-3cawA:
2.5		 1upfC-3cawA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE EPSILON SUBUNIT

(Methanosarcina
barkeri) 		PF02552
(CO_dh) 		4 MET G  89
ALA G  87
TYR G  84
ILE G  85
 ACY  G 171 ( 4.4A)
None
ACY  A 818 ( 4.9A)
None
 1.15A 1upfC-3cf4G:
3.1		 1upfC-3cf4G:
19.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dmp URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Burkholderia
pseudomallei) 		PF14681
(UPRTase) 		5 MET A 137
ALA A 139
TYR A 199
ILE A 200
ASP A 206
 None
 0.60A 1upfC-3dmpA:
26.1		 1upfC-3dmpA:
37.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqn GLUCAN
1,3-BETA-GLUCOSIDASE

(Phanerochaete
chrysosporium) 		PF12708
(Pectate_lyase_3) 		4 ALA A 413
TYR A 434
ILE A 414
ASP A 430
 None
 1.11A 1upfC-3eqnA:
undetectable		 1upfC-3eqnA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdb PUTATIVE
UNCHARACTERIZED
PROTEIN SPR0440

(Streptococcus
pneumoniae) 		PF03644
(Glyco_hydro_85) 		4 ALA A 515
TYR A 254
ILE A 514
ASP A 491
 None
 1.15A 1upfC-3gdbA:
undetectable		 1upfC-3gdbA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7f SERINE
HYDROXYMETHYLTRANSFE
RASE 1

(Mycobacterium
tuberculosis) 		PF00464
(SHMT) 		4 ALA A 105
TYR A 243
ILE A 247
ASP A 219
 None
 0.98A 1upfC-3h7fA:
3.7		 1upfC-3h7fA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hag CAPSID PROTEIN

(Orthohepevirus
A) 		PF03014
(SP2) 		4 ALA A 339
TYR A 413
ILE A 425
ASP A 422
 None
 1.04A 1upfC-3hagA:
undetectable		 1upfC-3hagA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq0 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 MET A 218
ALA A 214
TYR A 395
ILE A 275
 None
 1.12A 1upfC-3jq0A:
undetectable		 1upfC-3jq0A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l22 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 MET A 228
ALA A 224
TYR A 350
ILE A 273
 None
 1.09A 1upfC-3l22A:
undetectable		 1upfC-3l22A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mca PROTEIN DOM34

(Schizosaccharomyces
pombe) 		PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		4 ALA B 225
TYR B 220
ILE B 221
ASP B 187
 None
 0.96A 1upfC-3mcaB:
undetectable		 1upfC-3mcaB:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwt NUCLEOPROTEIN

(Lassa
mammarenavirus) 		PF00843
(Arena_nucleocap)
PF17290
(Arena_ncap_C) 		4 MET A 388
ALA A 401
ILE A 400
ASP A 466
 None
 1.17A 1upfC-3mwtA:
undetectable		 1upfC-3mwtA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nrk LIC12922

(Leptospira
interrogans) 		PF13145
(Rotamase_2)
PF13624
(SurA_N_3) 		4 ALA A  55
TYR A 346
ILE A  54
ASP A  96
 None
 1.07A 1upfC-3nrkA:
undetectable		 1upfC-3nrkA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q7b NUCLEOPROTEIN

(Lassa
mammarenavirus) 		PF17290
(Arena_ncap_C) 		4 MET A 388
ALA A 401
ILE A 400
ASP A 466
 None
 1.17A 1upfC-3q7bA:
undetectable		 1upfC-3q7bA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpi CHLORITE DISMUTASE

(Nitrobacter
winogradskyi) 		PF06778
(Chlor_dismutase) 		4 ALA A 124
TYR A 121
ILE A 125
ASP A 157
 None
None
HEM  A1001 ( 4.3A)
None
 0.98A 1upfC-3qpiA:
undetectable		 1upfC-3qpiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6x OUTER CAPSID PROTEIN
SIGMA-1

(Mammalian
orthoreovirus) 		PF01664
(Reo_sigma1) 		4 MET A 309
ALA A 301
TYR A 298
ILE A 300
 None
 1.11A 1upfC-3s6xA:
undetectable		 1upfC-3s6xA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uyj LYSINE-SPECIFIC
DEMETHYLASE 8

(Homo sapiens) 		PF13621
(Cupin_8) 		4 ALA A 230
TYR A 225
ILE A 226
ASP A 288
 None
 1.16A 1upfC-3uyjA:
undetectable		 1upfC-3uyjA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zs6 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Burkholderia
pseudomallei) 		PF00496
(SBP_bac_5) 		4 ALA A  49
TYR A 531
ILE A 552
ASP A 279
 None
 0.94A 1upfC-3zs6A:
undetectable		 1upfC-3zs6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3g DNA-BINDING PROTEIN
SMUBP-2

(Homo sapiens) 		PF13086
(AAA_11)
PF13087
(AAA_12) 		4 MET A 423
ALA A 427
ILE A 211
ASP A 400
 None
 1.04A 1upfC-4b3gA:
undetectable		 1upfC-4b3gA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d72 GLYCOSIDE HYDROLASE

(Streptococcus
pneumoniae) 		PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C) 		4 MET A 527
ALA A 524
ILE A 562
ASP A 566
 None
FUC  A2007 ( 4.0A)
None
None
 1.09A 1upfC-4d72A:
undetectable		 1upfC-4d72A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dth VGRG PROTEIN

(Vibrio cholerae) 		PF16671
(ACD) 		4 ALA A 230
TYR A 236
ILE A 237
ASP A 241
 None
 1.12A 1upfC-4dthA:
undetectable		 1upfC-4dthA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eun THERMORESISTANT
GLUCOKINASE

(Janibacter sp.
HTCC2649) 		PF01202
(SKI) 		4 MET A  49
ALA A  47
ILE A  46
ASP A  59
 None
 0.69A 1upfC-4eunA:
undetectable		 1upfC-4eunA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9z NUCLEOPROTEIN

(Lassa
mammarenavirus) 		PF17290
(Arena_ncap_C) 		4 MET A 388
ALA A 401
ILE A 400
ASP A 466
 None
None
None
G  F   6 ( 4.6A)
 1.12A 1upfC-4g9zA:
undetectable		 1upfC-4g9zA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jh8 METALLOTHIOL
TRANSFERASE FOSB

(Bacillus cereus) 		PF00903
(Glyoxalase) 		4 ALA A  38
TYR A  22
ILE A  19
ASP A 108
 None
 1.14A 1upfC-4jh8A:
undetectable		 1upfC-4jh8A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kcb ARABINAN
ENDO-1,5-ALPHA-L-ARA
BINOSIDASE

(uncultured
bacterium) 		PF04616
(Glyco_hydro_43) 		4 ALA A 122
TYR A 111
ILE A 123
ASP A 142
 None
 1.11A 1upfC-4kcbA:
undetectable		 1upfC-4kcbA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7t NANU SIALIC ACID
BINDING PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 MET A 211
ALA A 207
TYR A 388
ILE A 268
 None
 1.13A 1upfC-4l7tA:
undetectable		 1upfC-4l7tA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ldp NDP-FOROSAMYLTRANSFE
RASE

(Saccharopolyspora
spinosa) 		PF06722
(DUF1205) 		4 ALA A 204
TYR A 221
ILE A 222
ASP A 155
 None
 1.17A 1upfC-4ldpA:
undetectable		 1upfC-4ldpA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lhs UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF14606
(Lipase_GDSL_3)
PF14607
(GxDLY) 		4 ALA A 353
TYR A 350
ILE A 354
ASP A 243
 None
 1.14A 1upfC-4lhsA:
3.1		 1upfC-4lhsA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nb0 METALLOTHIOL
TRANSFERASE FOSB

(Staphylococcus
aureus) 		PF00903
(Glyoxalase) 		4 ALA A  38
TYR A  22
ILE A  19
ASP A 108
 None
 0.99A 1upfC-4nb0A:
undetectable		 1upfC-4nb0A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oon PENICILLIN-BINDING
PROTEIN 1A

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase)
PF00912
(Transgly)
PF17092
(PCB_OB) 		4 MET A 267
ALA A 265
TYR A 263
ILE A 264
 None
 1.04A 1upfC-4oonA:
undetectable		 1upfC-4oonA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pe5 GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B

(Rattus
norvegicus) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 ALA B 244
TYR B 239
ILE B 240
ASP B 211
 None
 1.11A 1upfC-4pe5B:
5.8		 1upfC-4pe5B:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tll RECEPTOR SUBUNIT
GLUN2B

(Xenopus laevis) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 ALA B 239
TYR B 234
ILE B 235
ASP B 206
 None
 1.18A 1upfC-4tllB:
5.1		 1upfC-4tllB:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tq5 PRENYLTRANSFERASE

(Archaeoglobus
fulgidus) 		PF01040
(UbiA) 		4 ALA A 159
TYR A 139
ILE A 135
ASP A 152
 None
 0.76A 1upfC-4tq5A:
undetectable		 1upfC-4tq5A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udn PERIPLASMIC SOLUTE
BINDING PROTEIN

(Candidatus
Liberibacter
asiaticus) 		PF01297
(ZnuA) 		4 ALA A 233
TYR A 240
ILE A 218
ASP A 226
 None
 0.97A 1upfC-4udnA:
undetectable		 1upfC-4udnA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wn9 NITROGENASE
MOLYBDENUM-IRON
PROTEIN ALPHA CHAIN

(Clostridium
pasteurianum) 		PF00148
(Oxidored_nitro) 		4 MET A 272
ALA A 270
TYR A 268
ILE A 269
 None
 1.11A 1upfC-4wn9A:
undetectable		 1upfC-4wn9A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x0r INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX2

(Homo sapiens) 		no annotation 4 MET B 155
ALA B 152
TYR B 212
ILE B 209
 None
 0.94A 1upfC-4x0rB:
undetectable		 1upfC-4x0rB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ycs UNCHARACTERIZED
PROTEIN

(Clostridioides
difficile) 		PF02608
(Bmp) 		4 MET A  65
ALA A  69
ILE A 136
ASP A  56
 GOL  A 201 ( 4.3A)
None
None
None
 1.08A 1upfC-4ycsA:
2.4		 1upfC-4ycsA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yn1 FUSOLIN

(Anomala cuprea
entomopoxvirus) 		PF03067
(LPMO_10) 		4 MET A  33
ALA A  37
ILE A 113
ASP A 230
 EDO  A 405 ( 3.5A)
None
None
None
 1.10A 1upfC-4yn1A:
undetectable		 1upfC-4yn1A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aoc ESTERASE

(Thermogutta
terrifontis) 		PF07859
(Abhydrolase_3) 		4 MET A  75
ALA A  71
TYR A  69
ASP A 269
 None
None
EDO  A1292 (-4.1A)
None
 0.92A 1upfC-5aocA:
2.3		 1upfC-5aocA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awp ISOMALTODEXTRANASE

(Arthrobacter
globiformis) 		no annotation 4 MET A 314
ALA A 342
TYR A  36
ILE A 341
 None
 0.99A 1upfC-5awpA:
undetectable		 1upfC-5awpA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7z LACTOYLGLUTATHIONE
LYASE

(Zea mays) 		PF00903
(Glyoxalase) 		4 ALA A  64
TYR A  42
ILE A  39
ASP A 137
 None
 1.08A 1upfC-5d7zA:
undetectable		 1upfC-5d7zA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d7z LACTOYLGLUTATHIONE
LYASE

(Zea mays) 		PF00903
(Glyoxalase) 		4 ALA A 194
TYR A 172
ILE A 169
ASP A 271
 None
 1.06A 1upfC-5d7zA:
undetectable		 1upfC-5d7zA:
20.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e38 URACIL
PHOSPHORIBOSYLTRANSF
ERASE

(Mycobacterium
tuberculosis) 		PF14681
(UPRTase) 		5 MET A 131
ALA A 133
TYR A 191
ILE A 192
ASP A 198
 None
 0.61A 1upfC-5e38A:
25.0		 1upfC-5e38A:
33.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9u GLYCOSYLTRANSFERASE-
STABILIZING PROTEIN
GTF2

(Streptococcus
gordonii) 		no annotation 4 ALA B 370
TYR B 389
ILE B 377
ASP B 386
 None
 1.01A 1upfC-5e9uB:
undetectable		 1upfC-5e9uB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f6q METALLOTHIOL
TRANSFERASE FOSB 2

(Bacillus
anthracis) 		PF00903
(Glyoxalase) 		4 ALA A  38
TYR A  22
ILE A  19
ASP A 108
 None
 1.03A 1upfC-5f6qA:
undetectable		 1upfC-5f6qA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f75 THIOCYANATE
DEHYDROGENASE

(Thioalkalivibrio
paradoxus) 		no annotation 4 ALA A 466
TYR A 448
ILE A 464
ASP A 515
 None
 1.03A 1upfC-5f75A:
undetectable		 1upfC-5f75A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB

(Cyanothece sp.
ATCC 51142) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		4 ALA A 148
TYR A 193
ILE A 195
ASP A 207
 None
 1.07A 1upfC-5gr1A:
undetectable		 1upfC-5gr1A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gtq LUCIFERIN
REGENERATING ENZYME

(Photinus
pyralis) 		PF08450
(SGL) 		4 MET A 125
ALA A 157
ILE A 158
ASP A 128
 None
None
MPD  A 405 ( 4.6A)
None
 1.12A 1upfC-5gtqA:
undetectable		 1upfC-5gtqA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jh8 PROBABLE CHITINASE

(Chromobacterium
violaceum) 		PF00704
(Glyco_hydro_18) 		4 ALA A 207
TYR A 287
ILE A 210
ASP A 199
 None
 1.18A 1upfC-5jh8A:
2.1		 1upfC-5jh8A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lq3 CMEB

(Campylobacter
jejuni) 		PF00873
(ACR_tran) 		4 MET A 625
ALA A 623
ILE A 574
ASP A 590
 None
 1.17A 1upfC-5lq3A:
undetectable		 1upfC-5lq3A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 ALA A 792
TYR A 787
ILE A 788
ASP A 754
 None
 1.13A 1upfC-5m59A:
2.2		 1upfC-5m59A:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m60 BETA-1,3-GLUCANASE

(Chaetomium
thermophilum) 		PF12708
(Pectate_lyase_3) 		4 ALA A 430
TYR A 451
ILE A 431
ASP A 447
 None
 1.12A 1upfC-5m60A:
undetectable		 1upfC-5m60A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofn DNA PRIMASE SMALL
SUBUNIT PRIS

(Sulfolobus
solfataricus) 		no annotation 4 MET A  94
ALA A 189
TYR A 185
ASP A  32
 None
 1.16A 1upfC-5ofnA:
undetectable		 1upfC-5ofnA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t8y EPOXYQUEUOSINE
REDUCTASE

(Bacillus
subtilis) 		PF08331
(DUF1730)
PF13484
(Fer4_16)
PF13646
(HEAT_2) 		4 MET A 172
ALA A 170
ILE A  73
ASP A 114
 None
 0.91A 1upfC-5t8yA:
undetectable		 1upfC-5t8yA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2a AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Brucella canis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 ALA A 370
TYR A 372
ILE A 439
ASP A 436
 None
 1.17A 1upfC-5u2aA:
3.1		 1upfC-5u2aA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ua5 5-HL

(African swine
fever virus) 		PF00452
(Bcl-2) 		4 ALA A  98
TYR A  23
ILE A  20
ASP A  47
 None
 1.08A 1upfC-5ua5A:
undetectable		 1upfC-5ua5A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5up2 N-METHYL-D-ASPARTATE
RECEPTOR SUBUNIT
NR2A

(Xenopus laevis) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 ALA B 235
TYR B 230
ILE B 231
ASP B 204
 None
 1.15A 1upfC-5up2B:
5.2		 1upfC-5up2B:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w6l RTX
REPEAT-CONTAINING
CYTOTOXIN

(Vibrio
vulnificus) 		no annotation 4 MET A3999
ALA A4004
ILE A3848
ASP A3721
 TYR  A4000 ( 3.4A)
ALA  A4004 ( 0.0A)
ILE  A3848 ( 0.7A)
ASP  A3721 ( 0.6A)
 1.15A 1upfC-5w6lA:
undetectable		 1upfC-5w6lA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wy3 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 MET A 346
ALA A 344
ILE A 343
ASP A 310
 None
 0.88A 1upfC-5wy3A:
undetectable		 1upfC-5wy3A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5t ALPHA-KETOGLUTARIC
SEMIALDEHYDE
DEHYDROGENASE

(Azospirillum
brasilense) 		PF00171
(Aldedh) 		4 MET A  74
ALA A  78
ILE A 114
ASP A 119
 None
 0.95A 1upfC-5x5tA:
undetectable		 1upfC-5x5tA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cjq -

(-) 		no annotation 4 ALA A 305
TYR A 404
ILE A 407
ASP A 312
 None
 1.16A 1upfC-6cjqA:
undetectable		 1upfC-6cjqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d95 -

(-) 		no annotation 4 ALA A 283
TYR A 274
ILE A 174
ASP A 126
 None
 1.00A 1upfC-6d95A:
2.4		 1upfC-6d95A:
undetectable