SIMILAR PATTERNS OF AMINO ACIDS FOR 1UNJ_F_DVAF2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cj2 | PROTEIN(P-HYDROXYBENZOATEHYDROXYLASE) (Pseudomonasfluorescens) |
PF01494(FAD_binding_3) | 3 | THR A 192PRO A 194THR A 217 | None | 0.84A | 1unjF-1cj2A:undetectable | 1unjF-1cj2A:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cpt | CYTOCHROME P450-TERP (Pseudomonas sp.) |
PF00067(p450) | 3 | THR A 109PRO A 107THR A 111 | None | 0.78A | 1unjF-1cptA:undetectable | 1unjF-1cptA:5.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3d | [NIFE] HYDROGENASELARGE SUBUNIT (Desulfovibriodesulfuricans) |
PF00374(NiFeSe_Hases) | 3 | THR B 493PRO B 491THR B 492 | NoneFNE B 543 (-3.7A)FNE B 543 (-3.8A) | 0.83A | 1unjF-1e3dB:undetectable | 1unjF-1e3dB:4.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e8t | HEMAGGLUTININ-NEURAMINIDASE (Avianavulavirus 1) |
PF00423(HN) | 3 | THR A 396PRO A 392THR A 394 | None | 0.86A | 1unjF-1e8tA:undetectable | 1unjF-1e8tA:5.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3p | ANTIBODY FABFRAGMENT (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | THR H 64PRO H 60THR H 62 | None | 0.76A | 1unjF-1h3pH:undetectable | 1unjF-1h3pH:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 3 | THR A 555PRO A 553THR A 554 | None | 0.79A | 1unjF-1h7wA:undetectable | 1unjF-1h7wA:1.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3u | ASPARTASE (Bacillus sp.YM55-1) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 3 | THR A 149PRO A 146THR A 147 | None | 0.81A | 1unjF-1j3uA:undetectable | 1unjF-1j3uA:2.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 3 | THR A 97PRO A 95THR A 99 | None | 0.85A | 1unjF-1jioA:undetectable | 1unjF-1jioA:7.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kj0 | SERINE PROTEASEINHIBITOR I (Schistocercagregaria) |
PF05375(Pacifastin_I) | 3 | THR A 5PRO A 21THR A 20 | None | 0.86A | 1unjF-1kj0A:undetectable | 1unjF-1kj0A:38.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qaf | PROTEIN (COPPERAMINE OXIDASE) (Escherichiacoli) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3)PF07833(Cu_amine_oxidN1) | 3 | THR A 687PRO A 614THR A 688 | None | 0.77A | 1unjF-1qafA:undetectable | 1unjF-1qafA:2.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qyi | HYPOTHETICAL PROTEIN (Staphylococcusaureus) |
PF13242(Hydrolase_like) | 3 | THR A 245PRO A 241THR A 243 | None | 0.71A | 1unjF-1qyiA:undetectable | 1unjF-1qyiA:2.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rin | PEA LECTIN (Pisum sativum) |
PF00139(Lectin_legB) | 3 | THR A 26PRO A 13THR A 27 | None | 0.80A | 1unjF-1rinA:undetectable | 1unjF-1rinA:8.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tf1 | NEGATIVE REGULATOROF ALLANTOIN ANDGLYOXYLATEUTILIZATION OPERONS (Escherichiacoli) |
PF01614(IclR) | 3 | THR A 100PRO A 98THR A 99 | None | 0.85A | 1unjF-1tf1A:undetectable | 1unjF-1tf1A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tg5 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Arabidopsisthaliana) |
PF00903(Glyoxalase) | 3 | THR A 95PRO A 93THR A 94 | None | 0.83A | 1unjF-1tg5A:undetectable | 1unjF-1tg5A:3.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujt | KIAA1568 PROTEIN (Homo sapiens) |
PF00041(fn3) | 3 | THR A 111PRO A 29THR A 112 | None | 0.79A | 1unjF-1ujtA:undetectable | 1unjF-1ujtA:9.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zrt | CYTOCHROME B (Rhodobactercapsulatus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 3 | THR C 37PRO C 36THR C 241 | None | 0.78A | 1unjF-1zrtC:undetectable | 1unjF-1zrtC:5.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b42 | XYLANASE INHIBITOR-I (Triticumaestivum) |
PF14541(TAXi_C)PF14543(TAXi_N) | 3 | THR A 106PRO A 2THR A 107 | None | 0.85A | 1unjF-2b42A:undetectable | 1unjF-2b42A:3.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d07 | G/TMISMATCH-SPECIFICTHYMINE DNAGLYCOSYLASE (Homo sapiens) |
PF03167(UDG) | 3 | THR A 196PRO A 198THR A 121 | None | 0.84A | 1unjF-2d07A:undetectable | 1unjF-2d07A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kgy | POSSIBLE EXPORTEDPROTEIN (Mycobacteriumtuberculosis) |
no annotation | 3 | THR A 17PRO A 15THR A 16 | None | 0.82A | 1unjF-2kgyA:undetectable | 1unjF-2kgyA:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ksk | SUGARCANE DEFENSIN 5 (Saccharumofficinarum) |
PF00304(Gamma-thionin) | 3 | THR A 2PRO A 5THR A 4 | None | 0.86A | 1unjF-2kskA:undetectable | 1unjF-2kskA:8.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nnu | REGULATORY PROTEINE2 (Alphapapillomavirus9) |
PF00508(PPV_E2_N) | 3 | THR A 104PRO A 106THR A 107 | None | 0.80A | 1unjF-2nnuA:undetectable | 1unjF-2nnuA:5.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pff | FATTY ACID SYNTHASESUBUNIT BETA (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF16073(SAT) | 3 | THR B 56PRO B 54THR B 55 | None | 0.78A | 1unjF-2pffB:undetectable | 1unjF-2pffB:1.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r6f | EXCINUCLEASE ABCSUBUNIT A (Geobacillusstearothermophilus) |
PF00005(ABC_tran) | 3 | THR A 857PRO A 855THR A 856 | None | 0.85A | 1unjF-2r6fA:undetectable | 1unjF-2r6fA:2.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9q | ROUNDABOUT HOMOLOG 1 (Homo sapiens) |
PF07679(I-set)PF13927(Ig_3) | 3 | THR A 230PRO A 186THR A 228 | None | 0.77A | 1unjF-2v9qA:undetectable | 1unjF-2v9qA:10.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vf8 | EXCINUCLEASE ABCSUBUNIT A (Deinococcusradiodurans) |
PF00005(ABC_tran) | 3 | THR A 762PRO A 760THR A 761 | None | 0.86A | 1unjF-2vf8A:undetectable | 1unjF-2vf8A:1.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3q | INTERLEUKIN-15RECEPTOR ALPHA CHAIN (Homo sapiens) |
no annotation | 3 | THR B 57PRO B 59THR B 58 | None | 0.83A | 1unjF-2z3qB:undetectable | 1unjF-2z3qB:9.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z5l | TYLACTONE SYNTHASESTARTER MODULE ANDMODULES 1 & 2 (Streptomycesfradiae) |
PF08659(KR) | 3 | THR A 37PRO A 35THR A 36 | None | 0.80A | 1unjF-2z5lA:undetectable | 1unjF-2z5lA:6.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z5x | AMINE OXIDASE[FLAVIN-CONTAINING]A (Homo sapiens) |
PF01593(Amino_oxidase) | 3 | THR A 278PRO A 274THR A 276 | NoneFAD A 600 ( 4.9A)None | 0.73A | 1unjF-2z5xA:undetectable | 1unjF-2z5xA:1.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 3 | THR A 113PRO A 117THR A 115 | None | 0.81A | 1unjF-3ai7A:undetectable | 1unjF-3ai7A:1.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases) | 3 | THR A 547PRO A 545THR A 546 | NoneCYN A 605 ( 3.6A)CYN A 605 (-3.7A) | 0.80A | 1unjF-3ayxA:undetectable | 1unjF-3ayxA:1.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg6 | ADSEVERIN (Homo sapiens) |
PF00626(Gelsolin) | 3 | THR A 704PRO A 700THR A 702 | None | 0.76A | 1unjF-3fg6A:undetectable | 1unjF-3fg6A:3.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1q | ETHANOLAMINEUTILIZATION PROTEINEUTJ (Carboxydothermushydrogenoformans) |
PF14450(FtsA) | 3 | THR A 166PRO A 165THR A 147 | None | 0.81A | 1unjF-3h1qA:undetectable | 1unjF-3h1qA:4.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hag | CAPSID PROTEIN (OrthohepevirusA) |
PF03014(SP2) | 3 | THR A 217PRO A 219THR A 218 | None | 0.86A | 1unjF-3hagA:undetectable | 1unjF-3hagA:2.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hd8 | XYLANASE INHIBITOR (Triticumaestivum) |
PF14541(TAXi_C)PF14543(TAXi_N) | 3 | THR A 108PRO A 4THR A 109 | None | 0.84A | 1unjF-3hd8A:undetectable | 1unjF-3hd8A:3.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 3 | THR A 196PRO A 198THR A 197 | None | 0.86A | 1unjF-3hmjA:undetectable | 1unjF-3hmjA:0.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hoa | THERMOSTABLECARBOXYPEPTIDASE 1 (Thermusthermophilus) |
PF02074(Peptidase_M32) | 3 | THR A 259PRO A 246THR A 260 | None | 0.76A | 1unjF-3hoaA:undetectable | 1unjF-3hoaA:2.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ik4 | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Herpetosiphonaurantiacus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | THR A 4PRO A 2THR A 3 | None | 0.85A | 1unjF-3ik4A:undetectable | 1unjF-3ik4A:3.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ikm | DNA POLYMERASESUBUNIT GAMMA-1 (Homo sapiens) |
PF00476(DNA_pol_A) | 3 | THR A 638PRO A 635THR A 636 | None | 0.63A | 1unjF-3ikmA:undetectable | 1unjF-3ikmA:0.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k9d | ALDEHYDEDEHYDROGENASE (Listeriamonocytogenes) |
PF00171(Aldedh) | 3 | THR A 124PRO A 121THR A 122 | None CL A 465 (-4.1A) CL A 465 (-4.1A) | 0.82A | 1unjF-3k9dA:undetectable | 1unjF-3k9dA:3.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxm | ASPARTATECARBAMOYLTRANSFERASE (Yersinia pestis) |
PF00185(OTCace)PF02729(OTCace_N) | 3 | THR A 139PRO A 136THR A 137 | None | 0.86A | 1unjF-3lxmA:undetectable | 1unjF-3lxmA:3.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgg | METHYLTRANSFERASE (Methanosarcinamazei) |
PF13847(Methyltransf_31) | 3 | THR A 254PRO A 150THR A 248 | None | 0.83A | 1unjF-3mggA:undetectable | 1unjF-3mggA:7.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mh9 | LIPOPROTEIN LPRG (Mycobacteriumtuberculosis) |
no annotation | 3 | THR C 114PRO C 117THR C 116 | None | 0.80A | 1unjF-3mh9C:undetectable | 1unjF-3mh9C:5.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mha | LIPOPROTEIN LPRG (Mycobacteriumtuberculosis) |
PF07161(LppX_LprAFG) | 3 | THR A 114PRO A 117THR A 116 | None | 0.82A | 1unjF-3mhaA:undetectable | 1unjF-3mhaA:6.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3my7 | ALCOHOLDEHYDROGENASE/ACETALDEHYDE DEHYDROGENASE (Vibrioparahaemolyticus) |
PF00171(Aldedh) | 3 | THR A 119PRO A 116THR A 117 | None CL A 453 ( 4.6A) CL A 453 ( 4.4A) | 0.79A | 1unjF-3my7A:undetectable | 1unjF-3my7A:3.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nre | ALDOSE 1-EPIMERASE (Escherichiacoli) |
PF01263(Aldose_epim) | 3 | THR A 225PRO A 228THR A 226 | None | 0.84A | 1unjF-3nreA:undetectable | 1unjF-3nreA:10.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nz4 | PHENYLALANINEAMMONIA-LYASE (Taxuscanadensis) |
PF00221(Lyase_aromatic) | 3 | THR A 129PRO A 125THR A 127 | None | 0.71A | 1unjF-3nz4A:undetectable | 1unjF-3nz4A:1.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3op7 | AMINOTRANSFERASECLASS I AND II (Streptococcussuis) |
PF00155(Aminotran_1_2) | 3 | THR A 154PRO A 152THR A 153 | None | 0.86A | 1unjF-3op7A:undetectable | 1unjF-3op7A:2.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p40 | NEUROFASCIN (Homo sapiens) |
PF13927(Ig_3) | 3 | THR A 367PRO A 366THR A 410 | None | 0.82A | 1unjF-3p40A:undetectable | 1unjF-3p40A:2.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q1y | LIN2199 PROTEIN (Listeriainnocua) |
PF00294(PfkB) | 3 | THR A 270PRO A 266THR A 268 | None | 0.76A | 1unjF-3q1yA:undetectable | 1unjF-3q1yA:5.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rgw | MEMBRANE-BOUNDHYDROGENASE (NIFE)LARGE SUBUNIT HOXG (Cupriavidusnecator) |
PF00374(NiFeSe_Hases) | 3 | THR L 554PRO L 552THR L 553 | NoneNFU L1004 (-3.6A)NFU L1004 (-3.8A) | 0.81A | 1unjF-3rgwL:undetectable | 1unjF-3rgwL:1.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sc2 | SERINECARBOXYPEPTIDASE II(CPDW-II) (Triticumaestivum) |
PF00450(Peptidase_S10) | 3 | THR B 346PRO B 342THR B 344 | None | 0.68A | 1unjF-3sc2B:undetectable | 1unjF-3sc2B:7.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usc | HYDROGENASE-1 LARGECHAIN (Escherichiacoli) |
PF00374(NiFeSe_Hases) | 3 | THR L 533PRO L 531THR L 532 | NoneFCO L 601 (-3.5A)FCO L 601 (-3.7A) | 0.77A | 1unjF-3uscL:undetectable | 1unjF-3uscL:2.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpx | LIPASE (Ustilago maydis) |
PF03583(LIP) | 3 | THR A 23PRO A 25THR A 24 | None | 0.86A | 1unjF-3zpxA:undetectable | 1unjF-3zpxA:3.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aio | LIMIT DEXTRINASE (Hordeum vulgare) |
PF02922(CBM_48)PF11852(DUF3372) | 3 | THR A 69PRO A 65THR A 67 | None | 0.84A | 1unjF-4aioA:undetectable | 1unjF-4aioA:1.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4av6 | K(+)-STIMULATEDPYROPHOSPHATE-ENERGIZED SODIUM PUMP (Thermotogamaritima) |
PF03030(H_PPase) | 3 | THR A 423PRO A 420THR A 421 | None | 0.78A | 1unjF-4av6A:undetectable | 1unjF-4av6A:2.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btp | P1 (Pseudomonasphage phi8) |
no annotation | 3 | THR A 297PRO A 299THR A 295 | None | 0.71A | 1unjF-4btpA:undetectable | 1unjF-4btpA:3.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3o | HYDROGENASE-1 LARGESUBUNIT (Salmonellaenterica) |
PF00374(NiFeSe_Hases) | 3 | THR A 536PRO A 534THR A 535 | NoneNFU A1004 (-3.8A)NFU A1004 (-3.7A) | 0.80A | 1unjF-4c3oA:undetectable | 1unjF-4c3oA:2.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eog | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrococcusfuriosus) |
PF09455(Cas_DxTHG) | 3 | THR A 176PRO A 173THR A 174 | None | 0.85A | 1unjF-4eogA:undetectable | 1unjF-4eogA:5.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1h | TYROSYL-DNAPHOSPHODIESTERASE 2 (Danio rerio) |
PF03372(Exo_endo_phos) | 3 | THR A 211PRO A 209THR A 210 | None | 0.73A | 1unjF-4f1hA:undetectable | 1unjF-4f1hA:29.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fd0 | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidescaccae) |
PF07523(Big_3)PF13306(LRR_5) | 3 | THR A 217PRO A 192THR A 193 | None | 0.75A | 1unjF-4fd0A:undetectable | 1unjF-4fd0A:9.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fd0 | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidescaccae) |
PF07523(Big_3)PF13306(LRR_5) | 3 | THR A 217PRO A 192THR A 194 | None | 0.86A | 1unjF-4fd0A:undetectable | 1unjF-4fd0A:9.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdw | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidesovatus) |
PF07523(Big_3)PF13306(LRR_5) | 3 | THR A 217PRO A 192THR A 194 | None | 0.85A | 1unjF-4fdwA:undetectable | 1unjF-4fdwA:4.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ffc | 4-AMINOBUTYRATEAMINOTRANSFERASE(GABT) (Mycobacteroidesabscessus) |
PF00202(Aminotran_3) | 3 | THR A 73PRO A 423THR A 72 | None | 0.86A | 1unjF-4ffcA:undetectable | 1unjF-4ffcA:3.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fnq | ALPHA-GALACTOSIDASEAGAB (Geobacillusstearothermophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 3 | THR A 268PRO A 186THR A 187 | None | 0.81A | 1unjF-4fnqA:undetectable | 1unjF-4fnqA:1.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h16 | SHORT CHAIN ALCOHOLDEHYDROGENASE-RELATED DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 3 | THR A 148PRO A 145THR A 149 | P6G A 305 ( 4.5A)NoneNone | 0.85A | 1unjF-4h16A:undetectable | 1unjF-4h16A:3.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k24 | ANTI-UPAR ANTIBODY,HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | THR H 117PRO H 147THR H 116 | None | 0.72A | 1unjF-4k24H:undetectable | 1unjF-4k24H:7.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lpq | ERFK/YBIS/YCFS/YNHGFAMILY PROTEIN (Xylanimonascellulosilytica) |
PF01471(PG_binding_1)PF03734(YkuD) | 3 | THR A 248PRO A 250THR A 249 | None | 0.86A | 1unjF-4lpqA:undetectable | 1unjF-4lpqA:6.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mzy | NICOTINATEPHOSPHORIBOSYLTRANSFERASE (Enterococcusfaecalis) |
PF04095(NAPRTase) | 3 | THR A 358PRO A 360THR A 359 | NoneNoneMLA A 517 (-3.9A) | 0.83A | 1unjF-4mzyA:undetectable | 1unjF-4mzyA:6.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n8g | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Chromohalobactersalexigens) |
PF03480(DctP) | 3 | THR A 202PRO A 198THR A 200 | None | 0.84A | 1unjF-4n8gA:undetectable | 1unjF-4n8gA:7.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovj | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Alicyclobacillusacidocaldarius) |
PF13416(SBP_bac_8) | 3 | THR A 259PRO A 255THR A 257 | None | 0.73A | 1unjF-4ovjA:undetectable | 1unjF-4ovjA:4.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmh | PECTINESTERASE (Sitophilusoryzae) |
PF01095(Pectinesterase) | 3 | THR A 111PRO A 113THR A 143 | None | 0.76A | 1unjF-4pmhA:undetectable | 1unjF-4pmhA:3.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ry1 | PERIPLASMIC SOLUTEBINDING PROTEIN (Pectobacteriumatrosepticum) |
PF13416(SBP_bac_8) | 3 | THR A 301PRO A 303THR A 165 | None | 0.84A | 1unjF-4ry1A:undetectable | 1unjF-4ry1A:3.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 3 | THR A 166PRO A 168THR A 162 | None | 0.81A | 1unjF-4s3jA:undetectable | 1unjF-4s3jA:2.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzb | NITROGENASEMOLYBDENUM-IRONPROTEIN ALPHA CHAIN (Azotobactervinelandii) |
PF00148(Oxidored_nitro) | 3 | THR A 305PRO A 302THR A 303 | None | 0.84A | 1unjF-4wzbA:undetectable | 1unjF-4wzbA:4.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xnz | LIGHT CHAIN OFANTIBODY VRC06B (Homo sapiens) |
no annotation | 3 | THR L 97PRO L 8THR L 10 | None | 0.74A | 1unjF-4xnzL:undetectable | 1unjF-4xnzL:8.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xvh | CARBOHYDRATEESTERASE FAMILY 2(CE2) (Chaetomium) |
PF13472(Lipase_GDSL_2) | 3 | THR A 285PRO A 287THR A 288 | None | 0.80A | 1unjF-4xvhA:undetectable | 1unjF-4xvhA:3.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6f | GATING RING OFPOTASSIUM CHANNELSUBFAMILY T MEMBER 1 (Gallus gallus) |
PF03493(BK_channel_a) | 3 | THR C 973PRO C 975THR C 974 | None | 0.85A | 1unjF-5a6fC:undetectable | 1unjF-5a6fC:1.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bw8 | UBIQUITIN-LIKEPROTEIN MDY2 (Saccharomycescerevisiae) |
PF16843(Get5_bdg) | 3 | THR D 23PRO D 25THR D 21 | None | 0.77A | 1unjF-5bw8D:undetectable | 1unjF-5bw8D:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bwy | PLASMEPSIN-2 (Plasmodiumfalciparum) |
PF00026(Asp) | 3 | THR A 116PRO A 113THR A 114 | None | 0.86A | 1unjF-5bwyA:undetectable | 1unjF-5bwyA:2.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dis | MALTOSE-BINDINGPERIPLASMICPROTEIN,NUCLEAR PORECOMPLEX PROTEINNUP214 (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8) | 3 | THR D1946PRO D1943THR D1944 | None | 0.82A | 1unjF-5disD:undetectable | 1unjF-5disD:2.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dyn | PUTATIVE PEPTIDASE (Bacteroidesfragilis) |
PF03415(Peptidase_C11) | 3 | THR B 282PRO B 278THR B 388 | None | 0.83A | 1unjF-5dynB:undetectable | 1unjF-5dynB:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5giv | CARBOXYPEPTIDASE 1 (Deinococcusradiodurans) |
PF02074(Peptidase_M32) | 3 | THR A 249PRO A 236THR A 250 | None | 0.83A | 1unjF-5givA:undetectable | 1unjF-5givA:1.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5has | SEC7 (Thielaviaterrestris) |
PF12783(Sec7_N)PF16213(DCB) | 3 | THR A 64PRO A 62THR A 66 | None | 0.82A | 1unjF-5hasA:undetectable | 1unjF-5hasA:2.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hs8 | HTH-TYPETRANSCRIPTIONALREGULATOR YODB (Bacillussubtilis) |
PF01638(HxlR) | 3 | THR A 39PRO A 43THR A 41 | None | 0.70A | 1unjF-5hs8A:undetectable | 1unjF-5hs8A:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ify | GLUCOSE-1-PHOSPHATETHYMIDYLYLTRANSFERASE (Burkholderiavietnamiensis) |
PF00483(NTP_transferase) | 3 | THR A 56PRO A 83THR A 81 | None | 0.85A | 1unjF-5ifyA:undetectable | 1unjF-5ifyA:6.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j44 | SERINE PROTEASE SEPAAUTOTRANSPORTER (Shigellaflexneri) |
PF02395(Peptidase_S6) | 3 | THR A 54PRO A 62THR A 56 | None | 0.86A | 1unjF-5j44A:undetectable | 1unjF-5j44A:1.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j78 | ACETALDEHYDEDEHYDROGENASE(ACETYLATING) (Parageobacillusthermoglucosidasius) |
PF00171(Aldedh) | 3 | THR A 146PRO A 143THR A 144 | NoneACT A1005 (-3.9A)ACT A1005 (-3.3A) | 0.78A | 1unjF-5j78A:undetectable | 1unjF-5j78A:2.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jfm | ALDEHYDEDEHYDROGENASE (Rhodopseudomonaspalustris) |
PF00171(Aldedh) | 3 | THR A 203PRO A 200THR A 201 | None | 0.79A | 1unjF-5jfmA:undetectable | 1unjF-5jfmA:3.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lj3 | PRE-MRNA-SPLICINGFACTOR BUD31 (Saccharomycescerevisiae) |
PF01125(G10) | 3 | THR L 24PRO L 21THR L 22 | None | 0.84A | 1unjF-5lj3L:undetectable | 1unjF-5lj3L:7.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqz | PUTATIVEBRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE (Archaeoglobusfulgidus) |
no annotation | 3 | THR A 199PRO A 201THR A 228 | NoneNoneTAM A 303 (-3.9A) | 0.83A | 1unjF-5mqzA:undetectable | 1unjF-5mqzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ngk | GLUCOSYLCERAMIDASE (Bacteroidesthetaiotaomicron) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 3 | THR A 69PRO A 67THR A 68 | None | 0.78A | 1unjF-5ngkA:undetectable | 1unjF-5ngkA:1.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o2v | NUCLEOLYSIN TIA-1ISOFORM P40 (Homo sapiens) |
PF00076(RRM_1) | 3 | THR A 83PRO A 6THR A 82 | None | 0.86A | 1unjF-5o2vA:undetectable | 1unjF-5o2vA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5of4 | GENERALTRANSCRIPTION FACTORIIH SUBUNIT4,P52,GENERALTRANSCRIPTION FACTORIIH SUBUNIT 4 (Homo sapiens) |
no annotation | 3 | THR D 388PRO D 385THR D 386 | None | 0.67A | 1unjF-5of4D:undetectable | 1unjF-5of4D:10.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tte | E3 UBIQUITIN-PROTEINLIGASE ARIH1 (Homo sapiens) |
PF01485(IBR) | 3 | THR B 131PRO B 127THR B 129 | None | 0.76A | 1unjF-5tteB:undetectable | 1unjF-5tteB:9.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udh | E3 UBIQUITIN-PROTEINLIGASE ARIH1 (Homo sapiens) |
PF01485(IBR) | 3 | THR A 131PRO A 127THR A 129 | None | 0.80A | 1unjF-5udhA:undetectable | 1unjF-5udhA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujz | SCFV (Homo sapiens) |
PF07686(V-set) | 3 | THR G 104PRO G 8THR G 10 | None | 0.73A | 1unjF-5ujzG:undetectable | 1unjF-5ujzG:3.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w1u | CARBOXYLIC ESTERHYDROLASE (Culexquinquefasciatus) |
PF00135(COesterase) | 3 | THR A 502PRO A 504THR A 505 | None | 0.70A | 1unjF-5w1uA:undetectable | 1unjF-5w1uA:2.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyn | PLATINUM SENSITIVITYPROTEIN 3 (Saccharomycescerevisiae) |
no annotation | 3 | THR A 209PRO A 181THR A 182 | None | 0.85A | 1unjF-5xynA:undetectable | 1unjF-5xynA:3.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PHOSPHATIDYLINOSITOL4-KINASE III ALPHA(PI4KA) (Homo sapiens) |
no annotation | 3 | THR A1076PRO A1073THR A1074 | None | 0.85A | 1unjF-6bq1A:undetectable | 1unjF-6bq1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cri | - (-) |
no annotation | 3 | THR M 154PRO M 150THR M 152 | None | 0.85A | 1unjF-6criM:undetectable | 1unjF-6criM:undetectable |