SIMILAR PATTERNS OF AMINO ACIDS FOR 1UDU_A_CIAA1003_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aux | SYNAPSIN IA (Bos taurus) |
PF02078(Synapsin)PF02750(Synapsin_C) | 5 | TYR A 129ALA A 127PHE A 130LEU A 116GLN A 145 | None | 0.96A | 1uduA-1auxA:undetectable | 1uduA-1auxA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1djp | GLUTAMINASE-ASPARAGINASE (Pseudomonas sp.7A) |
PF00710(Asparaginase) | 5 | SER A1220VAL A1113LEU A1221ILE A1315MET A1318 | None | 1.24A | 1uduA-1djpA:undetectable | 1uduA-1djpA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1efp | PROTEIN (ELECTRONTRANSFERFLAVOPROTEIN) (Paracoccusdenitrificans) |
PF01012(ETF) | 5 | TYR B 211ILE B 104VAL B 108ALA B 109ILE B 117 | None | 1.08A | 1uduA-1efpB:undetectable | 1uduA-1efpB:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fno | PEPTIDASE T (Salmonellaenterica) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 165VAL A 167PHE A 169LEU A 38ILE A 50 | None | 1.17A | 1uduA-1fnoA:undetectable | 1uduA-1fnoA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ifv | PROTEIN LLR18B (Lupinus luteus) |
PF00407(Bet_v_1) | 5 | ILE A 115VAL A 117ALA A 4PHE A 119LEU A 126 | None | 1.19A | 1uduA-1ifvA:undetectable | 1uduA-1ifvA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1igw | ISOCITRATE LYASE (Escherichiacoli) |
PF00463(ICL) | 5 | TYR A 282SER A 28ILE A 210VAL A 214ALA A 215 | None | 1.00A | 1uduA-1igwA:undetectable | 1uduA-1igwA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jsc | ACETOHYDROXY-ACIDSYNTHASE (Saccharomycescerevisiae) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | SER A 324ILE A 421ALA A 372LEU A 304ILE A 370 | None | 1.13A | 1uduA-1jscA:undetectable | 1uduA-1jscA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kae | HISTIDINOLDEHYDROGENASE (Escherichiacoli) |
PF00815(Histidinol_dh) | 5 | SER A 69VAL A 178ALA A 173ILE A 169PHE A 182 | None | 1.19A | 1uduA-1kaeA:undetectable | 1uduA-1kaeA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m2v | PROTEIN TRANSPORTPROTEIN SEC24 (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | SER B 446ALA B 323LEU B 321ILE B 537PHE B 544 | None | 1.13A | 1uduA-1m2vB:0.8 | 1uduA-1m2vB:14.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m3s | HYPOTHETICAL PROTEINYCKF (Bacillussubtilis) |
PF01380(SIS) | 5 | ILE A 84ALA A 51PHE A 54LEU A 58ILE A 67 | None | 1.10A | 1uduA-1m3sA:undetectable | 1uduA-1m3sA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbb | CYTOCHROME C' (Rhodobactercapsulatus) |
PF01322(Cytochrom_C_2) | 5 | TYR A 13VAL A 51ALA A 52PHE A 55MET A 78 | NBN A 131 ( 4.3A)NBN A 131 (-4.3A)NoneHEM A 130 ( 4.9A)None | 1.28A | 1uduA-1nbbA:0.6 | 1uduA-1nbbA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oqv | TOXIN-COREGULATEDPILUS SUBUNIT (Vibrio cholerae) |
PF05946(TcpA) | 5 | VAL A 194ALA A 195PHE A 196LEU A 40PHE A 88 | None | 1.24A | 1uduA-1oqvA:undetectable | 1uduA-1oqvA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pd1 | PROTEIN TRANSPORTPROTEIN SEC24 (Saccharomycescerevisiae) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | SER A 446ALA A 323LEU A 321ILE A 537PHE A 544 | None | 1.23A | 1uduA-1pd1A:undetectable | 1uduA-1pd1A:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pk8 | RAT SYNAPSIN I (Rattusnorvegicus) |
PF02078(Synapsin)PF02750(Synapsin_C) | 5 | TYR A 129ALA A 127PHE A 130LEU A 116GLN A 145 | None | 0.95A | 1uduA-1pk8A:undetectable | 1uduA-1pk8A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1spi | FRUCTOSE1,6-BISPHOSPHATASE (Spinaciaoleracea) |
PF00316(FBPase) | 5 | SER A 46ALA A 105PHE A 91LEU A 95ILE A 103 | None | 1.11A | 1uduA-1spiA:undetectable | 1uduA-1spiA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1veu | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE 1 INTERACTINGPROTEIN 1 (Mus musculus) |
PF08923(MAPKK1_Int) | 5 | SER A 15VAL A 35ALA A 36LEU A 19ILE A 93 | None | 1.29A | 1uduA-1veuA:undetectable | 1uduA-1veuA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vpx | PROTEIN(TRANSALDOLASE (EC2.2.1.2)) (Thermotogamaritima) |
PF00923(TAL_FSA) | 5 | ILE A 160ALA A 174ILE A 165MET A 184PHE A 4 | GOL A 219 ( 4.7A)NoneNoneNoneNone | 1.22A | 1uduA-1vpxA:undetectable | 1uduA-1vpxA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z7e | PROTEIN ARNA (Escherichiacoli) |
PF00551(Formyl_trans_N)PF01370(Epimerase)PF02911(Formyl_trans_C) | 5 | ILE A 88ALA A 7PHE A 82LEU A 19ILE A 29 | None | 1.29A | 1uduA-1z7eA:undetectable | 1uduA-1z7eA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkl | HIGH-AFFINITYCAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 7A (Homo sapiens) |
PF00233(PDEase_I) | 7 | TYR A 211VAL A 380PHE A 384LEU A 401ILE A 409GLN A 413PHE A 416 | IBM A 503 (-4.6A)IBM A 503 (-4.7A)IBM A 503 (-4.5A)NoneNoneIBM A 503 (-3.0A)IBM A 503 (-3.4A) | 0.88A | 1uduA-1zklA:34.1 | 1uduA-1zklA:28.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ful | EUKARYOTICTRANSLATIONINITIATION FACTOR 5 (Saccharomycescerevisiae) |
PF02020(W2) | 5 | ILE A 328ALA A 385PHE A 388LEU A 392MET A 362 | None | 1.10A | 1uduA-2fulA:undetectable | 1uduA-2fulA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g8l | 287AA LONGHYPOTHETICAL PROTEIN (Pyrococcushorikoshii) |
PF01937(DUF89) | 5 | ILE A 105VAL A 101ALA A 100PHE A 97ILE A 166 | None | 1.10A | 1uduA-2g8lA:undetectable | 1uduA-2g8lA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3b | HUMAN CANCER-RELATEDNTPASE (Homo sapiens) |
PF03266(NTPase_1) | 5 | ILE A 138VAL A 4PHE A 166LEU A 176ILE A 18 | None | 1.17A | 1uduA-2i3bA:undetectable | 1uduA-2i3bA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o34 | HYPOTHETICAL PROTEIN (Desulfovibriovulgaris) |
no annotation | 5 | ILE A 108VAL A 112ALA A 113PHE A 116LEU A 44 | None | 1.25A | 1uduA-2o34A:undetectable | 1uduA-2o34A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ocd | L-ASPARAGINASE I (Vibrio cholerae) |
PF00710(Asparaginase) | 5 | VAL A 205PHE A 105LEU A 101ILE A 208GLN A 69 | None | 1.06A | 1uduA-2ocdA:undetectable | 1uduA-2ocdA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r7a | BACTERIAL HEMEBINDING PROTEIN (Shigelladysenteriae) |
PF01497(Peripla_BP_2) | 5 | SER A 54ILE A 26VAL A 28ALA A 29ILE A 65 | None | 1.26A | 1uduA-2r7aA:undetectable | 1uduA-2r7aA:19.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2r8q | CLASS IPHOSPHODIESTERASEPDEB1 (Leishmaniamajor) |
PF00233(PDEase_I) | 5 | TYR A 680VAL A 853PHE A 857GLN A 887PHE A 890 | IBM A 3 ( 4.7A)IBM A 3 ( 4.8A)IBM A 3 (-4.9A)IBM A 3 (-3.3A)IBM A 3 (-3.6A) | 0.58A | 1uduA-2r8qA:37.0 | 1uduA-2r8qA:30.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wan | PULLULANASE (Bacillusacidopullulyticus) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 5 | TYR A 554SER A 636VAL A 552PHE A 621LEU A 648 | None | 1.19A | 1uduA-2wanA:undetectable | 1uduA-2wanA:15.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wjs | LAMININ SUBUNITALPHA-2 (Mus musculus) |
PF00054(Laminin_G_1) | 5 | ILE A2635VAL A2633PHE A2631LEU A2595ILE A2546 | None | 1.28A | 1uduA-2wjsA:undetectable | 1uduA-2wjsA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xio | PUTATIVEDEOXYRIBONUCLEASETATDN1 (Homo sapiens) |
PF01026(TatD_DNase) | 5 | SER A 214VAL A 273ALA A 272LEU A 281PHE A 195 | None | 1.12A | 1uduA-2xioA:undetectable | 1uduA-2xioA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y25 | MYOMESIN (Homo sapiens) |
PF07679(I-set) | 5 | SER A1657ILE A1584VAL A1582LEU A1578PHE A1631 | None | 1.24A | 1uduA-2y25A:undetectable | 1uduA-2y25A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a52 | COLD-ACTIVE ALKALINEPHOSPHATASE (Shewanella sp.AP1) |
PF00245(Alk_phosphatase) | 5 | SER A 276ILE A 191ALA A 229LEU A 275ILE A 226 | None | 1.29A | 1uduA-3a52A:undetectable | 1uduA-3a52A:22.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b2r | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 9 | TYR A 612ILE A 778VAL A 782ALA A 783PHE A 786ILE A 813MET A 816GLN A 817PHE A 820 | VDN A 1 (-4.8A)NoneVDN A 1 ( 4.7A)VDN A 1 ( 4.0A)NoneVDN A 1 ( 4.2A)VDN A 1 (-4.0A)VDN A 1 (-3.0A)VDN A 1 (-3.6A) | 0.74A | 1uduA-3b2rA:43.4 | 1uduA-3b2rA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8a | HEXOKINASE-1 (Saccharomycescerevisiae) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 5 | SER X 479VAL X 206ALA X 207LEU X 480ILE X 466 | None | 1.19A | 1uduA-3b8aX:undetectable | 1uduA-3b8aX:21.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bjc | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 9 | TYR A 612ILE A 778VAL A 782ALA A 783PHE A 786ILE A 813MET A 816GLN A 817PHE A 820 | NoneNoneWAN A 901 ( 4.9A)WAN A 901 (-3.6A)WAN A 901 (-4.8A)WAN A 901 ( 4.3A)WAN A 901 (-4.3A)WAN A 901 (-3.1A)WAN A 901 (-3.7A) | 0.65A | 1uduA-3bjcA:44.6 | 1uduA-3bjcA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctm | CARBONYL REDUCTASE (Candidaparapsilosis) |
PF13561(adh_short_C2) | 5 | TYR A 254ILE A 46VAL A 50ALA A 51ILE A 63 | None | 1.01A | 1uduA-3ctmA:undetectable | 1uduA-3ctmA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d89 | RIESKEDOMAIN-CONTAININGPROTEIN (Mus musculus) |
PF13806(Rieske_2) | 5 | ILE A 55VAL A 42ALA A 52LEU A 89ILE A 119 | None | 1.23A | 1uduA-3d89A:undetectable | 1uduA-3d89A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d89 | RIESKEDOMAIN-CONTAININGPROTEIN (Mus musculus) |
PF13806(Rieske_2) | 5 | VAL A 42ALA A 52PHE A 44LEU A 89ILE A 119 | None | 1.27A | 1uduA-3d89A:undetectable | 1uduA-3d89A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ez9 | PARA (Salmonellaenterica) |
PF13614(AAA_31) | 5 | SER A 316ILE A 393VAL A 389ALA A 388PHE A 385 | None | 1.24A | 1uduA-3ez9A:undetectable | 1uduA-3ez9A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ezq | PROTEIN FADDTUMOR NECROSISFACTOR RECEPTORSUPERFAMILY MEMBER 6 (Homo sapiens) |
PF00531(Death) | 5 | TYR A 232ILE A 236VAL B 103ALA B 100LEU B 165 | None | 1.23A | 1uduA-3ezqA:undetectable | 1uduA-3ezqA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f6m | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Yersinia pestis) |
PF02542(YgbB) | 5 | ILE A 148VAL A 41ALA A 42ILE A 98PHE A 7 | None | 1.19A | 1uduA-3f6mA:undetectable | 1uduA-3f6mA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 5 | SER A1678ILE A1386ALA A1393ILE A1400PHE A 992 | None | 1.28A | 1uduA-3hmjA:undetectable | 1uduA-3hmjA:10.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hwr | 2-DEHYDROPANTOATE2-REDUCTASE (Cupriaviduspinatubonensis) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | TYR A 196ILE A 238ALA A 184LEU A 264ILE A 180 | BCN A 301 (-4.5A)NoneNoneNoneNone | 1.12A | 1uduA-3hwrA:undetectable | 1uduA-3hwrA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3o | SHORT CHAINDEHYDROGENASE (Bacillusanthracis) |
PF13561(adh_short_C2) | 5 | TYR A 262ILE A 56VAL A 60PHE A 64ILE A 73 | NoneNAE A 311 (-3.8A)NoneNoneNone | 1.21A | 1uduA-3i3oA:undetectable | 1uduA-3i3oA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ilr | HEPARIN LYASE I (Bacteroidesthetaiotaomicron) |
PF14099(Polysacc_lyase) | 5 | TYR A 90ILE A 31VAL A 37ALA A 38ILE A 47 | None | 1.28A | 1uduA-3ilrA:undetectable | 1uduA-3ilrA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j97 | VESICLE-FUSINGATPASE (Cricetulusgriseus) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2) | 5 | VAL A 60ALA A 61PHE A 62LEU A 72ILE A 74 | None | 1.28A | 1uduA-3j97A:undetectable | 1uduA-3j97A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kly | PUTATIVE FORMATETRANSPORTER 1 (Vibrio cholerae) |
PF01226(Form_Nir_trans) | 5 | ILE A 238ALA A 226PHE A 225LEU A 132MET A 218 | None | 1.16A | 1uduA-3klyA:undetectable | 1uduA-3klyA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kv1 | TRANSCRIPTIONALREPRESSOR (Aliivibriofischeri) |
PF04198(Sugar-bind) | 5 | SER A 44ILE A 243VAL A 245ALA A 22ILE A 24 | GOL A 284 (-3.2A)NoneNoneNoneNone | 1.17A | 1uduA-3kv1A:undetectable | 1uduA-3kv1A:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kw0 | CYSTEINE PEPTIDASE (Bacillus cereus) |
PF05708(Peptidase_C92) | 5 | TYR A 14SER A 93ILE A 18ILE A 191PHE A 27 | None | 1.08A | 1uduA-3kw0A:undetectable | 1uduA-3kw0A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lg3 | ISOCITRATE LYASE (Yersinia pestis) |
PF00463(ICL) | 5 | TYR A 283SER A 29ILE A 211VAL A 215ALA A 216 | None | 1.03A | 1uduA-3lg3A:undetectable | 1uduA-3lg3A:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ls2 | S-FORMYLGLUTATHIONEHYDROLASE (Pseudoalteromonashaloplanktis) |
PF00756(Esterase) | 5 | SER A 264ILE A 143ALA A 169PHE A 170PHE A 61 | None | 1.26A | 1uduA-3ls2A:undetectable | 1uduA-3ls2A:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nm1 | THIAMINEBIOSYNTHETICBIFUNCTIONAL ENZYME ([Candida]glabrata) |
PF02110(HK)PF02581(TMP-TENI) | 5 | ILE A 472VAL A 493LEU A 537ILE A 253PHE A 486 | None | 1.08A | 1uduA-3nm1A:undetectable | 1uduA-3nm1A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ors | N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDEMUTASE (Staphylococcusaureus) |
PF00731(AIRC) | 5 | VAL A 81ALA A 74LEU A 69MET A 44PHE A 47 | None | 1.20A | 1uduA-3orsA:undetectable | 1uduA-3orsA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qan | 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE1 (Bacillushalodurans) |
PF00171(Aldedh) | 5 | VAL A 422ALA A 423PHE A 424LEU A 337MET A 385 | None | 1.27A | 1uduA-3qanA:undetectable | 1uduA-3qanA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qnb | OXACILLINASE (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | SER A 172ILE A 112VAL A 188LEU A 178ILE A 76 | EDO A 10 (-2.7A)NoneNoneNoneNone | 1.23A | 1uduA-3qnbA:undetectable | 1uduA-3qnbA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3s | OXIDOREDUCTASE (Salmonellaenterica) |
PF13561(adh_short_C2) | 5 | TYR A 269ILE A 61ALA A 66LEU A 53ILE A 78 | NoneNAD A 300 (-3.7A)NoneNoneNone | 1.08A | 1uduA-3r3sA:undetectable | 1uduA-3r3sA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjy | ENDOGLUCANASEFNCEL5A (Fervidobacteriumnodosum) |
PF00150(Cellulase) | 5 | ILE A 145VAL A 149ALA A 150PHE A 153LEU A 160 | None | 0.73A | 1uduA-3rjyA:undetectable | 1uduA-3rjyA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr0 | GUANYLATE KINASE (Coxiellaburnetii) |
PF00625(Guanylate_kin) | 5 | ILE A 178VAL A 174ALA A 173PHE A 170ILE A 121 | None | 0.99A | 1uduA-3tr0A:undetectable | 1uduA-3tr0A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vth | HYDROGENASEMATURATION FACTOR (Caldanaerobactersubterraneus) |
PF00708(Acylphosphatase)PF01300(Sua5_yciO_yrdC)PF07503(zf-HYPF) | 5 | SER A 670ILE A 559ALA A 606ILE A 551PHE A 600 | None | 1.25A | 1uduA-3vthA:undetectable | 1uduA-3vthA:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1j | L-SERYL-TRNA(SEC)SELENIUM TRANSFERASE (Aquifexaeolicus) |
PF03841(SelA) | 5 | SER A 250ILE A 302VAL A 296PHE A 268ILE A 276 | None | 1.18A | 1uduA-3w1jA:undetectable | 1uduA-3w1jA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zmr | CELLULASE (GLYCOSYLHYDROLASE FAMILY 5) (Bacteroidesovatus) |
PF00150(Cellulase)PF13004(BACON) | 5 | ILE A 250ALA A 293PHE A 292LEU A 290ILE A 247 | None | 1.16A | 1uduA-3zmrA:undetectable | 1uduA-3zmrA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b96 | CELLULOSE BINDINGDOMAIN-CONTAININGPROTEIN ([Clostridium]clariflavum) |
PF00942(CBM_3) | 5 | VAL A 57ALA A 56PHE A 55LEU A 86PHE A 25 | None | 1.21A | 1uduA-4b96A:undetectable | 1uduA-4b96A:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxi | ACCESSORY GENEREGULATOR PROTEIN C (Staphylococcusaureus) |
PF14501(HATPase_c_5) | 5 | ILE A 311VAL A 354ALA A 355PHE A 365ILE A 315 | None | 1.29A | 1uduA-4bxiA:undetectable | 1uduA-4bxiA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cd8 | ENDO-BETA-1,4-MANNANASE (Alicyclobacillusacidocaldarius) |
no annotation | 5 | TYR A 262VAL A 310ALA A 311PHE A 314GLN A 42 | None | 0.80A | 1uduA-4cd8A:undetectable | 1uduA-4cd8A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cn8 | PROXIMAL THREADMATRIX PROTEIN 1 (Mytilusgalloprovincialis) |
PF00092(VWA) | 5 | ILE A 407VAL A 416ALA A 394LEU A 435ILE A 392 | None | 1.21A | 1uduA-4cn8A:undetectable | 1uduA-4cn8A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dpg | LYSINE--TRNA LIGASE (Homo sapiens) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 5 | ILE A 564ALA A 555PHE A 557ILE A 551MET A 549 | None | 1.26A | 1uduA-4dpgA:undetectable | 1uduA-4dpgA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e09 | PLASMID PARTITIONINGPROTEIN PARF (Escherichiacoli) |
PF01656(CbiA) | 5 | ALA A 161PHE A 162LEU A 197ILE A 137PHE A 6 | None | 1.19A | 1uduA-4e09A:undetectable | 1uduA-4e09A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fin | ETTA (YJJK) ABCFFAMILY PROTEIN (Escherichiacoli) |
PF00005(ABC_tran)PF12848(ABC_tran_Xtn) | 5 | ILE A 229VAL A 37ALA A 214LEU A 185PHE A 29 | None | 1.22A | 1uduA-4finA:undetectable | 1uduA-4finA:21.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4htz | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 6 | TYR A 655ILE A 822PHE A 830ILE A 855GLN A 859PHE A 862 | None | 0.68A | 1uduA-4htzA:39.1 | 1uduA-4htzA:35.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k6e | MRNA-DECAPPINGENZYME SUBUNIT 2 (Saccharomycescerevisiae) |
PF00293(NUDIX) | 5 | ALA A 108PHE A 131LEU A 120ILE A 110PHE A 207 | None | 1.06A | 1uduA-4k6eA:undetectable | 1uduA-4k6eA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4khb | UNCHARACTERIZEDPROTEIN POB3N (Chaetomiumthermophilum) |
no annotation | 5 | ILE D 145VAL D 147PHE D 149LEU D 175PHE D 127 | None | 1.25A | 1uduA-4khbD:undetectable | 1uduA-4khbD:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9z | HUMAN PROTEIN KINASEC THETA (Homo sapiens) |
PF00069(Pkinase)PF00433(Pkinase_C) | 5 | SER A 433ILE A 518ALA A 521LEU A 432MET A 458 | NoneNonePZW A 801 ( 4.6A)NonePZW A 801 (-4.4A) | 1.13A | 1uduA-4q9zA:undetectable | 1uduA-4q9zA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qed | ELXO (Staphylococcusepidermidis) |
PF13561(adh_short_C2) | 5 | ILE A 15VAL A 19ALA A 20PHE A 23ILE A 32 | NAP A 300 (-3.7A)NoneNoneNoneNone | 0.63A | 1uduA-4qedA:undetectable | 1uduA-4qedA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y61 | SLIT AND NTRK-LIKEPROTEIN 2 (Mus musculus) |
PF13855(LRR_8) | 5 | TYR B 138ILE B 164VAL B 162ILE B 208MET B 209 | None | 0.97A | 1uduA-4y61B:undetectable | 1uduA-4y61B:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yb9 | SOLUTE CARRIERFAMILY 2,FACILITATED GLUCOSETRANSPORTER MEMBER 5 (Bos taurus) |
PF00083(Sugar_tr) | 5 | ILE D 172VAL D 176ALA D 177PHE D 180LEU D 198 | None | 0.91A | 1uduA-4yb9D:undetectable | 1uduA-4yb9D:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ye2 | CAPPING ENZYMEPROTEIN (Rotavirus A) |
PF05213(Corona_NS2A) | 5 | ILE A 798VAL A 767LEU A 771ILE A 795PHE A 721 | NoneNoneNoneA2P A 901 (-3.9A)None | 1.28A | 1uduA-4ye2A:undetectable | 1uduA-4ye2A:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a22 | VESICULAR STOMATITISVIRUS L POLYMERASE (Vesicularstomatitisvirus) |
PF00946(Mononeg_RNA_pol)PF14314(Methyltrans_Mon)PF14318(Mononeg_mRNAcap) | 5 | SER A 891ILE A 122VAL A 126LEU A 892MET A 833 | None | 1.26A | 1uduA-5a22A:undetectable | 1uduA-5a22A:9.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b25 | CALCIUM/CALMODULIN-DEPENDENT3',5'-CYCLICNUCLEOTIDEPHOSPHODIESTERASE 1B (Homo sapiens) |
PF00233(PDEase_I) | 5 | TYR A 222PHE A 392LEU A 409GLN A 421PHE A 424 | NoneGOL A 607 (-3.9A)GOL A 607 (-4.6A)4QJ A 603 (-3.0A)4QJ A 603 (-3.5A) | 1.05A | 1uduA-5b25A:33.8 | 1uduA-5b25A:28.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dpt | PLECKSTRIN HOMOLOGYDOMAIN-CONTAININGFAMILY M MEMBER 1,GAMMA-AMINOBUTYRICACIDRECEPTOR-ASSOCIATEDPROTEIN-LIKE1,GAMMA-AMINOBUTYRICACIDRECEPTOR-ASSOCIATEDPROTEIN-LIKE 1 (Homo sapiens) |
PF02991(Atg8) | 5 | ILE A 39VAL A 114ALA A 115PHE A 85LEU A 83 | None | 1.18A | 1uduA-5dptA:undetectable | 1uduA-5dptA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5esz | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE,ENVELOPEGLYCOPROTEIN GP160 (Haemophilusinfluenzae;Humanimmunodeficiencyvirus 1) |
PF00516(GP120)PF02542(YgbB) | 5 | ILE C 305VAL C 204ALA C 205ILE C 255PHE C 119 | None | 1.16A | 1uduA-5eszC:undetectable | 1uduA-5eszC:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ftz | CHITIN BINDINGPROTEIN (Streptomyceslividans) |
PF03067(LPMO_10) | 5 | SER A 172VAL A 199PHE A 201LEU A 174PHE A 150 | None | 1.18A | 1uduA-5ftzA:undetectable | 1uduA-5ftzA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gmt | ALGINATE LYASE (Aplysia kurodai) |
no annotation | 5 | SER A 149ILE A 158VAL A 157ILE A 143GLN A 165 | None | 1.20A | 1uduA-5gmtA:undetectable | 1uduA-5gmtA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h0k | UNCHARACTERIZEDPROTEIN (Pedobacterheparinus) |
PF16265(DUF4918) | 5 | TYR A 46SER A 55VAL A 8PHE A 4GLN A 165 | None | 1.21A | 1uduA-5h0kA:undetectable | 1uduA-5h0kA:20.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5h2r | PHOSPHODIESTERASE (Trypanosomabrucei) |
no annotation | 5 | TYR A 668VAL A 841PHE A 845GLN A 875PHE A 878 | LLN A1003 ( 4.8A)LLN A1003 (-4.6A)LLN A1003 (-4.6A)LLN A1003 (-3.0A)LLN A1003 (-3.8A) | 0.70A | 1uduA-5h2rA:36.7 | 1uduA-5h2rA:32.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h4r | BETA-1,3-1,4-GLUCANASE (Caldicellulosiruptorsp. F32) |
PF00150(Cellulase) | 5 | ILE A 166VAL A 170ALA A 171PHE A 174LEU A 181 | None | 0.67A | 1uduA-5h4rA:undetectable | 1uduA-5h4rA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | SER A 60ILE A 30VAL A 32ALA A 33ILE A 35 | None | 1.21A | 1uduA-5ip9A:undetectable | 1uduA-5ip9A:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ivw | GENERALTRANSCRIPTION FACTORIIH SUBUNIT 3 (Homo sapiens) |
PF03850(Tfb4) | 5 | SER 3 35ILE 3 60VAL 3 15LEU 3 34MET 3 119 | None | 1.28A | 1uduA-5ivw3:undetectable | 1uduA-5ivw3:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jy1 | PUTATIVE SHORT-CHAINDEHYDROGENASE/REDUCTASE (Paraburkholderiaxenovorans) |
PF13561(adh_short_C2) | 5 | ILE A 18VAL A 22ALA A 23PHE A 26ILE A 35 | NAD A 301 (-3.8A)NoneNoneNoneNone | 0.77A | 1uduA-5jy1A:undetectable | 1uduA-5jy1A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jyd | SHORT CHAINDEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | TYR A 289ILE A 81ALA A 86LEU A 73ILE A 98 | NoneNAD A 901 (-3.8A)NoneNoneNone | 1.16A | 1uduA-5jydA:undetectable | 1uduA-5jydA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jyd | SHORT CHAINDEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | TYR A 289ILE A 81ALA A 86PHE A 89ILE A 98 | NoneNAD A 901 (-3.8A)NoneNoneNone | 1.09A | 1uduA-5jydA:undetectable | 1uduA-5jydA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l75 | LIPOPOLYSACCHARIDEABC TRANSPORTER,ATP-BINDING PROTEINLPTB (Klebsiellapneumoniae) |
PF00005(ABC_tran)PF12399(BCA_ABC_TP_C) | 5 | SER A 23ILE A 192VAL A 32ALA A 207ILE A 209 | NoneNone PT A 301 (-4.9A)NoneNone | 1.20A | 1uduA-5l75A:undetectable | 1uduA-5l75A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | 2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESISPROTEIN PHLC (Pseudomonasprotegens) |
no annotation | 5 | SER C 274ILE C 377VAL C 379ALA C 295ILE C 313 | None | 1.16A | 1uduA-5mg5C:undetectable | 1uduA-5mg5C:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ore | OCTOPINE-BINDINGPERIPLASMIC PROTEIN (Agrobacteriumtumefaciens) |
no annotation | 5 | SER A 193VAL A 115ALA A 114ILE A 210MET A 215 | None | 1.14A | 1uduA-5oreA:undetectable | 1uduA-5oreA:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u7z | ACID CERAMIDASE (Homo sapiens) |
no annotation | 5 | TYR B 233ILE B 236ALA B 277ILE B 249PHE A 136 | None | 1.21A | 1uduA-5u7zB:undetectable | 1uduA-5u7zB:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wa0 | PUTATIVE SULFITEOXIDASE (Sinorhizobiummeliloti) |
no annotation | 6 | SER A 290VAL A 124ALA A 344PHE A 311ILE A 68PHE A 64 | None | 1.17A | 1uduA-5wa0A:undetectable | 1uduA-5wa0A:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x68 | KYNURENINE3-MONOOXYGENASE (Homo sapiens) |
no annotation | 5 | ILE A 215ALA A 225LEU A 197ILE A 199PHE A 261 | None | 1.27A | 1uduA-5x68A:undetectable | 1uduA-5x68A:14.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ygr | DIAMINOPROPIONATEAMMONIA LYASE (Salmonellaenterica) |
no annotation | 5 | SER A 348ILE A 261VAL A 263LEU A 297PHE A 242 | LLP A 78 ( 4.4A)NoneNoneNoneNone | 1.22A | 1uduA-5ygrA:undetectable | 1uduA-5ygrA:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6am0 | KLLA0F23980P (Kluyveromyceslactis) |
no annotation | 5 | ALA A 107PHE A 130LEU A 119ILE A 109PHE A 206 | None | 1.07A | 1uduA-6am0A:undetectable | 1uduA-6am0A:13.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byx | SHORT ULVAN LYASE (Alteromonas sp.LOR) |
no annotation | 5 | TYR A 94SER A 115VAL A 153ALA A 152LEU A 114 | None | 1.25A | 1uduA-6byxA:undetectable | 1uduA-6byxA:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c4m | YERSINOPINEDEHYDROGENASE (Yersinia pestis) |
no annotation | 5 | SER C 126VAL C 94ALA C 93LEU C 119ILE C 91 | NoneNAP C 501 (-3.7A)NAP C 501 (-4.8A)NoneNone | 1.27A | 1uduA-6c4mC:undetectable | 1uduA-6c4mC:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dd6 | PHOTOLYASE PHRB (Agrobacteriumtumefaciens) |
no annotation | 5 | ILE A 126VAL A 101ALA A 18ILE A 16GLN A 11 | None | 1.28A | 1uduA-6dd6A:undetectable | 1uduA-6dd6A:undetectable |