SIMILAR PATTERNS OF AMINO ACIDS FOR 1U70_A_MTXA187_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ghs 1,3-BETA-GLUCANASE

(Hordeum vulgare) 		PF00332
(Glyco_hydro_17) 		4 SER A 181
ILE A 180
VAL A 193
THR A 262
 None
 1.19A 1u70A-1ghsA:
0.2		 1u70A-1ghsA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1he3 BILIVERDIN IX BETA
REDUCTASE

(Homo sapiens) 		PF13460
(NAD_binding_10) 		4 SER A 202
ILE A 176
VAL A 149
THR A 191
 None
 1.12A 1u70A-1he3A:
1.8		 1u70A-1he3A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j6u UDP-N-ACETYLMURAMATE
-ALANINE LIGASE MURC

(Thermotoga
maritima) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 SER A 435
ILE A 431
VAL A 343
THR A 331
 None
 1.07A 1u70A-1j6uA:
4.2		 1u70A-1j6uA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lq2 BETA-D-GLUCAN
GLUCOHYDROLASE
ISOENZYME EXO1

(Hordeum vulgare) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 SER A 524
ILE A 523
VAL A 541
THR A 564
 None
 1.23A 1u70A-1lq2A:
undetectable		 1u70A-1lq2A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lrk UDP-GLUCOSE
4-EPIMERASE

(Escherichia
coli) 		PF16363
(GDP_Man_Dehyd) 		4 SER A 171
ILE A 172
VAL A  77
THR A  16
 None
 0.96A 1u70A-1lrkA:
0.8		 1u70A-1lrkA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nff PUTATIVE
OXIDOREDUCTASE
RV2002

(Mycobacterium
tuberculosis) 		PF13561
(adh_short_C2) 		4 SER A 139
ILE A 138
VAL A 234
THR A 201
 None
NAD  A1300 (-4.4A)
None
None
 1.23A 1u70A-1nffA:
1.9		 1u70A-1nffA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1n HYPOTHETICAL
ZINC-TYPE ALCOHOL
DEHYDROGENASE-LIKE
PROTEIN IN PRE5-FET4
INTERGENIC REGION

(Saccharomyces
cerevisiae) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 SER A 295
ILE A 296
VAL A 249
THR A 167
 None
 1.09A 1u70A-1q1nA:
1.8		 1u70A-1q1nA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qnh PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Plasmodium
falciparum) 		PF00160
(Pro_isomerase) 		4 SER A  27
ILE A  29
VAL A 134
THR A 122
 None
 1.18A 1u70A-1qnhA:
undetectable		 1u70A-1qnhA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sqe HYPOTHETICAL PROTEIN
PG130

(Staphylococcus
aureus) 		PF03992
(ABM) 		4 SER A 110
ILE A 108
VAL A  67
THR A  71
 None
 0.79A 1u70A-1sqeA:
undetectable		 1u70A-1sqeA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmr ISOPULLULANASE

(Aspergillus
niger) 		PF03718
(Glyco_hydro_49)
PF17433
(Glyco_hydro_49N) 		4 SER A 113
ILE A 112
VAL A  74
THR A  40
 None
 1.23A 1u70A-1wmrA:
undetectable		 1u70A-1wmrA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg0 B-PHYCOERYTHRIN BETA
CHAIN

(Rhodomonas sp.
CS24) 		PF00502
(Phycobilisome) 		4 SER C  32
ILE C  31
VAL C  41
THR C 153
 None
None
None
PEB  C 258 (-4.3A)
 1.21A 1u70A-1xg0C:
undetectable		 1u70A-1xg0C:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytk NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE FROM
THERMOPLASMA
ACIDOPHILUM

(Thermoplasma
acidophilum) 		PF01729
(QRPTase_C) 		4 SER A 296
ILE A 295
VAL A 163
THR A 179
 None
None
None
NCN  A 401 (-3.1A)
 1.05A 1u70A-1ytkA:
undetectable		 1u70A-1ytkA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zkp HYPOTHETICAL PROTEIN
BA1088

(Bacillus
anthracis) 		PF12706
(Lactamase_B_2) 		4 SER A 128
ILE A 127
VAL A 150
THR A 210
 None
 1.21A 1u70A-1zkpA:
undetectable		 1u70A-1zkpA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ahw PUTATIVE ENZYME YDIF

(Escherichia
coli) 		PF01144
(CoA_trans) 		4 SER A  80
ILE A  79
VAL A  88
THR A 158
 None
 1.22A 1u70A-2ahwA:
undetectable		 1u70A-2ahwA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyg BETA-1, 3-GLUCANANSE

(Musa acuminata) 		PF00332
(Glyco_hydro_17) 		4 SER A 215
ILE A 214
VAL A 228
THR A 296
 None
 0.98A 1u70A-2cygA:
undetectable		 1u70A-2cygA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D

(Methanothermobacter
thermautotrophicus) 		PF00710
(Asparaginase) 		4 SER A  94
ILE A  95
VAL A 198
THR A 183
 None
 1.15A 1u70A-2d6fA:
undetectable		 1u70A-2d6fA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f9z CHEMOTAXIS PROTEIN
CHEC

(Thermotoga
maritima) 		PF04509
(CheC) 		4 SER A  37
ILE A  36
VAL A 174
THR A  82
 None
 1.25A 1u70A-2f9zA:
undetectable		 1u70A-2f9zA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwn DIHYDROOROTASE

(Porphyromonas
gingivalis) 		PF01979
(Amidohydro_1) 		4 SER A 353
ILE A 357
VAL A 302
THR A 255
 None
 1.18A 1u70A-2gwnA:
undetectable		 1u70A-2gwnA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h3g BIOSYNTHETIC PROTEIN

(Bacillus
anthracis) 		PF03309
(Pan_kinase) 		4 SER X 228
ILE X 227
VAL X 128
THR X 242
 None
 1.11A 1u70A-2h3gX:
undetectable		 1u70A-2h3gX:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hsd 3-ALPHA, 20
BETA-HYDROXYSTEROID
DEHYDROGENASE

(Streptomyces
exfoliatus) 		PF13561
(adh_short_C2) 		4 SER A 138
ILE A 137
VAL A 239
THR A 205
 None
NAD  A 256 (-4.6A)
None
None
 1.14A 1u70A-2hsdA:
2.1		 1u70A-2hsdA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqa MINOR AMPULLATE
FIBROIN 1

(Nephila
antipodiana) 		PF12042
(RP1-2) 		4 SER A 112
ILE A 111
VAL A  58
THR A 128
 None
 1.05A 1u70A-2mqaA:
undetectable		 1u70A-2mqaA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pod MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME

(Burkholderia
pseudomallei) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 SER A 221
ILE A 247
VAL A 266
THR A 240
 None
 0.96A 1u70A-2podA:
undetectable		 1u70A-2podA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppv UNCHARACTERIZED
PROTEIN

(Staphylococcus
epidermidis) 		PF01933
(UPF0052) 		4 SER A 281
ILE A 283
VAL A 273
THR A 224
 None
 1.20A 1u70A-2ppvA:
1.8		 1u70A-2ppvA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq6 UDP-GLUCURONOSYL/UDP
-GLUCOSYLTRANSFERASE

(Medicago
truncatula) 		PF00201
(UDPGT) 		4 SER A 251
ILE A 252
VAL A 223
THR A 131
 None
 0.75A 1u70A-2pq6A:
undetectable		 1u70A-2pq6A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1u CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG

(Aeropyrum
pernix) 		PF09079
(Cdc6_C)
PF13191
(AAA_16) 		4 SER A 310
ILE A 311
VAL A 385
THR A 299
 None
 1.24A 1u70A-2v1uA:
undetectable		 1u70A-2v1uA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vt2 REDOX-SENSING
TRANSCRIPTIONAL
REPRESSOR REX

(Bacillus
subtilis) 		PF02629
(CoA_binding)
PF06971
(Put_DNA-bind_N) 		4 SER A 114
ILE A 113
VAL A 148
THR A 162
 None
 1.24A 1u70A-2vt2A:
2.2		 1u70A-2vt2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwb PUTATIVE
O-SIALOGLYCOPROTEIN
ENDOPEPTIDASE

(Methanocaldococcus
jannaschii) 		PF00814
(Peptidase_M22)
PF01163
(RIO1) 		4 SER A 379
ILE A 376
VAL A 192
THR A 453
 None
 1.06A 1u70A-2vwbA:
undetectable		 1u70A-2vwbA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vz9 FATTY ACID SYNTHASE

(Sus scrofa) 		PF00107
(ADH_zinc_N)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08242
(Methyltransf_12)
PF08659
(KR)
PF14765
(PS-DH)
PF16197
(KAsynt_C_assoc) 		4 SER A1056
ILE A1057
VAL A1089
THR A 972
 None
 1.21A 1u70A-2vz9A:
undetectable		 1u70A-2vz9A:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbe BIPOLAR KINESIN
KRP-130

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 SER C 145
ILE C 144
VAL C 227
THR C 313
 None
 1.15A 1u70A-2wbeC:
undetectable		 1u70A-2wbeC:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wge 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 1

(Mycobacterium
tuberculosis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 SER A 175
ILE A 178
VAL A 359
THR A  32
 None
 1.00A 1u70A-2wgeA:
undetectable		 1u70A-2wgeA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0f WSAF

(Geobacillus
stearothermophilus) 		no annotation 4 SER A 404
ILE A 406
VAL A 199
THR A 217
 None
 1.03A 1u70A-2x0fA:
undetectable		 1u70A-2x0fA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B

(Thermotoga
maritima) 		PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 SER B 166
ILE B 164
VAL B 227
THR B 262
 None
 1.23A 1u70A-3al0B:
undetectable		 1u70A-3al0B:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bz5 INTERNALIN-J

(Listeria
monocytogenes) 		PF12799
(LRR_4) 		4 SER A 103
ILE A 105
VAL A  75
THR A  84
 None
 1.06A 1u70A-3bz5A:
undetectable		 1u70A-3bz5A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ch2 SERINE-REPEAT
ANTIGEN PROTEIN

(Plasmodium
falciparum) 		PF00112
(Peptidase_C1) 		4 SER X 816
ILE X 814
VAL X 764
THR X 607
 None
 1.13A 1u70A-3ch2X:
undetectable		 1u70A-3ch2X:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ckk TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE

(Homo sapiens) 		PF02390
(Methyltransf_4) 		4 SER A 109
ILE A  78
VAL A  82
THR A 208
 None
SAM  A 301 (-3.8A)
None
SAM  A 301 (-2.8A)
 0.96A 1u70A-3ckkA:
undetectable		 1u70A-3ckkA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fyd PROBABLE
DIMETHYLADENOSINE
TRANSFERASE

(Methanocaldococcus
jannaschii) 		PF00398
(RrnaAD) 		4 SER A 107
ILE A 110
VAL A  98
THR A  45
 None
 1.01A 1u70A-3fydA:
undetectable		 1u70A-3fydA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g2p PCZA361.24

(Amycolatopsis
orientalis) 		PF13649
(Methyltransf_25) 		4 SER A 139
ILE A 142
VAL A 268
THR A  60
 None
 1.00A 1u70A-3g2pA:
undetectable		 1u70A-3g2pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gaf 7-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE

(Brucella
abortus) 		PF13561
(adh_short_C2) 		4 SER A 145
ILE A 144
VAL A 246
THR A 213
 None
 1.23A 1u70A-3gafA:
undetectable		 1u70A-3gafA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3grk ENOYL-(ACYL-CARRIER-
PROTEIN) REDUCTASE
(NADH)

(Brucella
melitensis) 		PF13561
(adh_short_C2) 		4 SER A 191
ILE A 190
VAL A 223
THR A 197
 None
 1.21A 1u70A-3grkA:
undetectable		 1u70A-3grkA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gry DIMETHYLADENOSINE
TRANSFERASE

(Methanocaldococcus
jannaschii) 		PF00398
(RrnaAD) 		4 SER A 107
ILE A 110
VAL A  98
THR A  45
 None
 0.89A 1u70A-3gryA:
undetectable		 1u70A-3gryA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2u KINESIN-LIKE PROTEIN
KLP10A

(Drosophila
melanogaster) 		PF00225
(Kinesin) 		4 SER K 503
ILE K 506
VAL K 416
THR K 404
 None
 1.25A 1u70A-3j2uK:
undetectable		 1u70A-3j2uK:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 SER X1151
ILE X1150
VAL X1143
THR X1100
 None
 1.01A 1u70A-3jb9X:
undetectable		 1u70A-3jb9X:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkl PROBABLE CHAPERONE
PROTEIN HSP33

(Saccharomyces
cerevisiae) 		no annotation 4 SER A   9
ILE A   8
VAL A 101
THR A 211
 None
 1.18A 1u70A-3kklA:
undetectable		 1u70A-3kklA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l76 ASPARTOKINASE

(Synechocystis
sp. PCC 6803) 		PF00696
(AA_kinase)
PF01842
(ACT)
PF13840
(ACT_7) 		4 SER A 569
ILE A 568
VAL A 435
THR A 198
 None
LYS  A 603 (-4.5A)
None
None
 1.21A 1u70A-3l76A:
undetectable		 1u70A-3l76A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1g PUTATIVE GLUTATHIONE
S-TRANSFERASE

(Corynebacterium
glutamicum) 		PF13409
(GST_N_2)
PF13410
(GST_C_2) 		4 SER A  87
ILE A  86
VAL A 147
THR A 134
 None
 1.24A 1u70A-3m1gA:
undetectable		 1u70A-3m1gA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n23 SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1

(Sus scrofa) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		4 SER A 200
ILE A 199
VAL A 184
THR A 240
 None
 1.10A 1u70A-3n23A:
undetectable		 1u70A-3n23A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nap CAPSID PROTEIN

(Triatoma virus) 		PF08762
(CRPV_capsid) 		4 SER A 238
ILE A 237
VAL A 253
THR A 257
 None
 1.25A 1u70A-3napA:
undetectable		 1u70A-3napA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3now UNC-45 PROTEIN,
SD10334P

(Drosophila
melanogaster) 		PF11701
(UNC45-central) 		4 SER A 648
ILE A 652
VAL A 578
THR A 544
 None
 1.25A 1u70A-3nowA:
undetectable		 1u70A-3nowA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE BETA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 SER B 443
ILE B 442
VAL B 450
THR B 426
 None
 1.18A 1u70A-3opyB:
undetectable		 1u70A-3opyB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qat MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Bartonella
henselae) 		PF00698
(Acyl_transf_1) 		4 SER A  69
ILE A  73
VAL A  90
THR A 273
 None
 1.00A 1u70A-3qatA:
undetectable		 1u70A-3qatA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN

(Bacteroides
caccae) 		PF12667
(NigD_N)
PF17415
(NigD_C) 		4 SER A  95
ILE A  93
VAL A  36
THR A 101
 None
None
None
CL  A 262 ( 4.3A)
 1.10A 1u70A-3qwnA:
undetectable		 1u70A-3qwnA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3svt SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCT
ASE

(Mycobacterium
ulcerans) 		PF13561
(adh_short_C2) 		4 SER A 146
ILE A 145
VAL A 248
THR A 215
 None
 1.18A 1u70A-3svtA:
undetectable		 1u70A-3svtA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sx2 PUTATIVE
3-KETOACYL-(ACYL-CAR
RIER-PROTEIN)
REDUCTASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 SER A 155
ILE A 154
VAL A 206
THR A 216
 None
NAD  A 300 (-4.7A)
NAD  A 300 (-4.1A)
None
 1.17A 1u70A-3sx2A:
undetectable		 1u70A-3sx2A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsn 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE

(Campylobacter
jejuni) 		PF04166
(PdxA) 		4 SER A   7
ILE A   6
VAL A 330
THR A 334
 None
 1.05A 1u70A-3tsnA:
undetectable		 1u70A-3tsnA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vf1 11R-LIPOXYGENASE

(Gersemia
fruticosa) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 SER A  22
ILE A  23
VAL A 114
THR A 130
 None
 1.09A 1u70A-3vf1A:
undetectable		 1u70A-3vf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E

(Streptomyces
cinnabarigriseus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 SER A 235
ILE A 238
VAL A 252
THR A 318
 None
None
NAP  A1447 (-3.8A)
None
 1.20A 1u70A-4a0sA:
2.2		 1u70A-4a0sA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a7p UDP-GLUCOSE
DEHYDROGENASE

(Sphingomonas
elodea) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 SER A 338
ILE A 340
VAL A 387
THR A 430
 None
 1.18A 1u70A-4a7pA:
undetectable		 1u70A-4a7pA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4btg MAJOR INNER PROTEIN
P1

(Pseudomonas
virus phi6) 		no annotation 4 SER A 539
ILE A 535
VAL A  31
THR A  17
 None
 1.02A 1u70A-4btgA:
undetectable		 1u70A-4btgA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e13 DIKETOREDUCTASE

(Acinetobacter
baylyi) 		PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 SER A 248
ILE A 247
VAL A 239
THR A 276
 1PE  A 306 (-3.1A)
1PE  A 306 ( 3.9A)
1PE  A 306 (-4.6A)
None
 1.19A 1u70A-4e13A:
undetectable		 1u70A-4e13A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6l AUSA REDUCTASE
DOMAIN PROTEIN

(Staphylococcus
aureus) 		no annotation 4 SER B2171
ILE B2226
VAL B2193
THR B2187
 None
 1.13A 1u70A-4f6lB:
undetectable		 1u70A-4f6lB:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gvl TRKA DOMAIN PROTEIN

(Geobacter
sulfurreducens) 		PF02080
(TrkA_C)
PF02254
(TrkA_N) 		4 SER A 304
ILE A 306
VAL A 519
THR A 537
 None
 0.97A 1u70A-4gvlA:
2.5		 1u70A-4gvlA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iis BETA-1,3-GLUCANASE
FORM 'RRII GLN 2'

(Hevea
brasiliensis) 		PF00332
(Glyco_hydro_17) 		4 SER A 191
ILE A 190
VAL A 204
THR A 271
 None
 1.04A 1u70A-4iisA:
undetectable		 1u70A-4iisA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnd CA(2+)/CALMODULIN-DE
PENDENT PROTEIN
KINASE PHOSPHATASE

(Caenorhabditis
elegans) 		PF00481
(PP2C) 		4 SER A 401
ILE A 404
VAL A 417
THR A 263
 None
 1.24A 1u70A-4jndA:
undetectable		 1u70A-4jndA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mow GLUCOSE
1-DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF13561
(adh_short_C2) 		4 SER A 140
ILE A 139
VAL A 243
THR A 210
 None
 1.16A 1u70A-4mowA:
undetectable		 1u70A-4mowA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nbt 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Acholeplasma
laidlawii) 		PF13561
(adh_short_C2) 		4 SER A 132
ILE A 131
VAL A 234
THR A 201
 None
NAD  A 301 (-3.9A)
None
None
 1.15A 1u70A-4nbtA:
undetectable		 1u70A-4nbtA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4odi PHOSPHOGLYCERATE
MUTASE PGMII

(Toxoplasma
gondii) 		PF00300
(His_Phos_1) 		4 SER A 187
ILE A 188
VAL A 196
THR A  89
 None
 1.14A 1u70A-4odiA:
1.7		 1u70A-4odiA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okm TERPENE SYNTHASE
METAL-BINDING
DOMAIN-CONTAINING
PROTEIN

(Streptomyces
pristinaespiralis) 		no annotation 4 SER A 322
ILE A 306
VAL A   7
THR A 329
 None
 1.24A 1u70A-4okmA:
undetectable		 1u70A-4okmA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q34 UNCHARACTERIZED
PROTEIN

(Parabacteroides
distasonis) 		PF12697
(Abhydrolase_6) 		4 SER A 215
ILE A 262
VAL A 222
THR A 237
 None
 1.13A 1u70A-4q34A:
undetectable		 1u70A-4q34A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rer 5'-AMP-ACTIVATED
PROTEIN KINASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00571
(CBS) 		4 SER G  54
ILE G 114
VAL G  83
THR G 163
 None
 1.19A 1u70A-4rerG:
undetectable		 1u70A-4rerG:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4umg PROTEIN LIN-41

(Caenorhabditis
elegans) 		PF00630
(Filamin) 		4 SER A 699
ILE A 808
VAL A 785
THR A 714
 None
 1.06A 1u70A-4umgA:
undetectable		 1u70A-4umgA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wuv 2-HYDROXYCYCLOHEXANE
CARBOXYL-COA
DEHYDROGENASE

(Haemophilus
influenzae) 		PF00106
(adh_short) 		4 SER A 167
ILE A 166
VAL A 275
THR A 241
 None
NAD  A 301 (-3.9A)
None
None
 1.16A 1u70A-4wuvA:
undetectable		 1u70A-4wuvA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y1b ANTE

(Streptomyces
sp. NRRL 2288) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 SER A 216
ILE A 219
VAL A 233
THR A 306
 None
None
NAP  A 501 (-3.9A)
NAP  A 501 (-3.9A)
 1.04A 1u70A-4y1bA:
2.2		 1u70A-4y1bA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydq PROLINE--TRNA LIGASE

(Plasmodium
falciparum) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09180
(ProRS-C_1) 		4 SER A 282
ILE A 281
VAL A 389
THR A 513
 None
 1.08A 1u70A-4ydqA:
undetectable		 1u70A-4ydqA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c41 RIBOKINASE

(Homo sapiens) 		PF00294
(PfkB) 		4 SER A  94
ILE A  93
VAL A  20
THR A 159
 None
 1.23A 1u70A-5c41A:
undetectable		 1u70A-5c41A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cef ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Cryptococcus
neoformans) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 SER A 208
ILE A 207
VAL A 194
THR A  17
 None
 0.91A 1u70A-5cefA:
undetectable		 1u70A-5cefA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzs SHIKIMATE
DEHYDROGENASE
(NADP(+))

(Clostridioides
difficile) 		PF08501
(Shikimate_dh_N) 		4 SER A 243
ILE A 246
VAL A  85
THR A 135
 None
 1.10A 1u70A-5dzsA:
2.0		 1u70A-5dzsA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejs MYOSIN-I HEAVY CHAIN

(Dictyostelium
discoideum) 		PF00373
(FERM_M)
PF00784
(MyTH4)
PF09380
(FERM_C) 		4 SER A2099
ILE A2100
VAL A2144
THR A2273
 None
 1.25A 1u70A-5ejsA:
undetectable		 1u70A-5ejsA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz TUBULIN GAMMA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 SER C 262
ILE C 260
VAL C 318
THR C 382
 None
 1.23A 1u70A-5flzC:
undetectable		 1u70A-5flzC:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 SER A 131
ILE A 129
VAL A  96
THR A  92
 None
 1.01A 1u70A-5fr8A:
undetectable		 1u70A-5fr8A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsw RNA DEPENDENT RNA
POLYMERASE QDE-1

(Thielavia
terrestris) 		PF05183
(RdRP) 		4 SER A 590
ILE A 592
VAL A 721
THR A 708
 None
 1.23A 1u70A-5fswA:
undetectable		 1u70A-5fswA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iob BETA-GLUCOSIDASE-REL
ATED GLYCOSIDASES

(Corynebacterium
glutamicum) 		PF00933
(Glyco_hydro_3) 		4 SER A 358
ILE A 360
VAL A  79
THR A 318
 None
 1.13A 1u70A-5iobA:
undetectable		 1u70A-5iobA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iv9 LPS-ASSEMBLY
LIPOPROTEIN LPTE
LPS-ASSEMBLY PROTEIN
LPTD

(Klebsiella
pneumoniae) 		PF03968
(OstA)
PF04390
(LptE)
PF04453
(OstA_C) 		4 SER B  81
ILE B  82
VAL B 122
THR A 614
 None
 1.04A 1u70A-5iv9B:
undetectable		 1u70A-5iv9B:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jod PROPLASMEPSIN IV

(Plasmodium
falciparum) 		PF00026
(Asp) 		4 SER A 278
ILE A 280
VAL A 246
THR A 219
 None
 1.24A 1u70A-5jodA:
undetectable		 1u70A-5jodA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kk5 CRISPR-ASSOCIATED
ENDONUCLEASE CPF1

(Acidaminococcus
sp. BV3L6) 		no annotation 4 SER A 778
ILE A 779
VAL A1027
THR A1046
 None
 1.02A 1u70A-5kk5A:
undetectable		 1u70A-5kk5A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mkt RENIN-1

(Mus musculus) 		no annotation 4 SER A 236
ILE A 235
VAL A 265
THR A  56
 None
 1.25A 1u70A-5mktA:
undetectable		 1u70A-5mktA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqc VP1
VP3

(Black queen
cell virus) 		PF08762
(CRPV_capsid)
no annotation 		4 SER C 119
ILE C 117
VAL A 109
THR C  22
 None
 1.25A 1u70A-5mqcC:
undetectable		 1u70A-5mqcC:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tge PHAGE TERMINASE
LARGE SUBUNIT

(Thermus virus
P74-26) 		PF17289
(Terminase_6C) 		4 SER A 382
ILE A 381
VAL A 371
THR A 367
 None
 1.07A 1u70A-5tgeA:
undetectable		 1u70A-5tgeA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uja BOVINE MULTIDRUG
RESISTANCE PROTEIN 1
(MRP1),MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1

(Bos taurus) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 SER A 604
ILE A 603
VAL A 477
THR A 556
 None
 1.16A 1u70A-5ujaA:
undetectable		 1u70A-5ujaA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um6 UBIQUITIN-ACTIVATING
ENZYME E1 1

(Schizosaccharomyces
pombe) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		4 SER A 161
ILE A 162
VAL A 127
THR A 143
 None
 1.10A 1u70A-5um6A:
undetectable		 1u70A-5um6A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vad BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE

(Homo sapiens) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09180
(ProRS-C_1) 		4 SER A1044
ILE A1043
VAL A1151
THR A1277
 None
 1.16A 1u70A-5vadA:
undetectable		 1u70A-5vadA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR

(Cavia
porcellus;
Escherichia
virus T4) 		no annotation 4 SER A 202
ILE A 206
VAL A 226
THR A  55
 None
 1.20A 1u70A-5x33A:
undetectable		 1u70A-5x33A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgc RAP1 GTPASE-GDP
DISSOCIATION
STIMULATOR 1

(Homo sapiens) 		PF00514
(Arm) 		4 SER A 422
ILE A 425
VAL A 398
THR A 355
 None
 1.24A 1u70A-5xgcA:
undetectable		 1u70A-5xgcA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xio PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE)

(Cryptosporidium
parvum) 		no annotation 4 SER A 254
ILE A 253
VAL A 361
THR A 485
 None
 1.09A 1u70A-5xioA:
undetectable		 1u70A-5xioA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xip PROLYL-TRNA
SYNTHETASE, PUTATIVE

(Eimeria tenella) 		no annotation 4 SER A 282
ILE A 281
VAL A 389
THR A 513
 None
 1.17A 1u70A-5xipA:
undetectable		 1u70A-5xipA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwq FUNGAL CHITINASE
FROM RHIZOMUCOR
MIEHEI (NATIVE
PROTEIN)

(Rhizomucor
miehei) 		no annotation 4 SER A 385
ILE A 384
VAL A 281
THR A 316
 None
 1.11A 1u70A-5xwqA:
undetectable		 1u70A-5xwqA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yb7 L-AMINO ACID
OXIDASE/MONOOXYGENAS
E

(Pseudomonas sp.
AIU 813) 		no annotation 4 SER A 106
ILE A  15
VAL A 250
THR A 232
 None
 1.19A 1u70A-5yb7A:
undetectable		 1u70A-5yb7A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c3p ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8

(Homo sapiens) 		no annotation 4 SER E1422
ILE E1423
VAL E1533
THR E1541
 None
 1.21A 1u70A-6c3pE:
undetectable		 1u70A-6c3pE:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f45 -

(-) 		no annotation 4 SER D  38
ILE D  37
VAL D  30
THR D  73
 None
 1.18A 1u70A-6f45D:
undetectable		 1u70A-6f45D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARD
CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARE

(Acetobacterium
woodii) 		no annotation 4 SER A 145
ILE A 148
VAL A 179
THR B  95
 None
None
None
FAD  B 301 (-2.7A)
 0.99A 1u70A-6fahA:
2.2		 1u70A-6fahA:
19.88